Human Phenotype Ontology

Input	HPO ID	HPO term	Distance	Gene	Gene id entrez	HGNC ID	DiseaseId	DiseaseName	Frequency	ClinVar variants
HPO disease - gene - phenotype typical associations:
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	ABCC9 CL E G H	10060	60	OMIM:619719	INTELLECTUAL DISABILITY AND MYOPATHY SYNDROME; IDMYS		254
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	ACSL4 CL E G H	2182	3571	OMIM:300387	MENTAL RETARDATION, X-LINKED 63; MRX63		19
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	ADCY5 CL E G H	111	236	OMIM:606703	Dyskinesia, familial, with facial myokymia		25
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	ADCY5 CL E G H	111	236	OMIM:619651	NEURODEVELOPMENTAL DISORDER WITH HYPERKINETIC MOVEMENTS AND DYSKINESIA; NEDHYD		25
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	ADGRV1 CL E G H	84059	17416	ORPHA:36387	Generalized epilepsy with febrile seizures-plus		530
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	ADGRV1 CL E G H	84059	17416	ORPHA:231178	Usher syndrome type 2		530
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	ADNP CL E G H	23394	15766	ORPHA:404448	ADNP syndrome		47
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	AIP CL E G H	9049	358	ORPHA:963	Acromegaly		95
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	AIP CL E G H	9049	358	OMIM:219090	Pituitary adenoma 4, ACTH-secreting, somatic	.	95
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	ALAD CL E G H	210	395	ORPHA:100924	Porphyria due to ALA dehydratase deficiency	HP:0040283 - Occasional	62
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	ALDH4A1 CL E G H	8659	406	ORPHA:79101	Hyperprolinemia type 2		74
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	ALDH5A1 CL E G H	7915	408	OMIM:271980	Succinic semialdehyde dehydrogenase deficiency		108
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	ALG14 CL E G H	199857	28287	OMIM:619031	INTELLECTUAL DEVELOPMENTAL DISORDER WITH EPILEPSY, BEHAVIORAL ABNORMALITIES, AND COARSE FACIES; IDDEBF		12
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	ANG CL E G H	283	483	ORPHA:803	Amyotrophic lateral sclerosis		32
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	ANXA11 CL E G H	311	535	ORPHA:803	Amyotrophic lateral sclerosis
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	AP1G1 CL E G H	164	555	OMIM:619467	USMANI-RIAZUDDIN SYNDROME, AUTOSOMAL DOMINANT; USRISD
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	APC2 CL E G H	10297	24036	ORPHA:821	Sotos syndrome		1
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	AR CL E G H	367	644	ORPHA:95706	Non-syndromic posterior hypospadias		125
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	ARID2 CL E G H	196528	18037	OMIM:617808	Coffin-siris syndrome 6		25
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	ARSG CL E G H	22901	24102	ORPHA:231183	Usher syndrome type 3
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	ARVCF CL E G H	421	728	ORPHA:567	22q11.2 deletion syndrome		1
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	ASH1L CL E G H	55870	19088	OMIM:617796	Mental retardation, autosomal dominant 52		1
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	ATP1A3 CL E G H	478	801	OMIM:128235	Dystonia 12		150
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	ATP1A3 CL E G H	478	801	ORPHA:71517	Rapid-onset dystonia-parkinsonism		150
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	ATRX CL E G H	546	886	ORPHA:96253	Cushing disease		169
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	ATXN2 CL E G H	6311	10555	ORPHA:803	Amyotrophic lateral sclerosis		11
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	BAZ1B CL E G H	9031	961	ORPHA:904	Williams syndrome
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	BCL11B CL E G H	64919	13222	OMIM:618092	INTELLECTUAL DEVELOPMENTAL DISORDER WITH SPEECH DELAY, DYSMORPHIC FACIES, AND T-CELL ABNORMALITIES		3
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	BCL7B CL E G H	9275	1005	ORPHA:904	Williams syndrome
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	BMPR1A CL E G H	657	1076	ORPHA:440437	Familial colorectal cancer Type X		385
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	BPTF CL E G H	2186	3581	ORPHA:529962	17q24.2 microdeletion syndrome		2
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	BRAF CL E G H	673	1097	ORPHA:96253	Cushing disease		276
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	BRD4 CL E G H	23476	13575	ORPHA:199	Cornelia de Lange syndrome
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	BUD23 CL E G H	114049	16405	ORPHA:904	Williams syndrome
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	C9ORF72 CL E G H	203228	28337	ORPHA:803	Amyotrophic lateral sclerosis		56
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	C9ORF72 CL E G H	203228	28337	ORPHA:401901	Huntington disease-like syndrome due to C9ORF72 expansions		56
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	C9ORF72 CL E G H	203228	28337	ORPHA:100070	Progressive non-fluent aphasia		56
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	CABP4 CL E G H	57010	1386	ORPHA:98784	Autosomal dominant nocturnal frontal lobe epilepsy		94
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	CACNA1A CL E G H	773	1388	OMIM:141500	Migraine, familial hemiplegic, 1		449
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	CACNA1H CL E G H	8912	1395	ORPHA:64280	Childhood absence epilepsy		75
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	CASR CL E G H	846	1514	ORPHA:428	Autosomal dominant hypocalcemia		272
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	CCND1 CL E G H	595	1582	ORPHA:892	Von Hippel-Lindau disease		1
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	CCNF CL E G H	899	1591	ORPHA:803	Amyotrophic lateral sclerosis
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	CDC42BPB CL E G H	9578	1738	OMIM:619841
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	CDH2 CL E G H	1000	1759	OMIM:618929	AGENESIS OF CORPUS CALLOSUM, CARDIAC, OCULAR, AND GENITAL SYNDROME; ACOGS
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	CDH23 CL E G H	64072	13733	ORPHA:96253	Cushing disease		636
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	CDH23 CL E G H	64072	13733	ORPHA:231169	Usher syndrome type 1		636
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	CDKL5 CL E G H	6792	11411	ORPHA:3095	Atypical Rett syndrome		405
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	CDKN2A CL E G H	1029	1787	ORPHA:1501	Adrenocortical carcinoma		289
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	CDON CL E G H	50937	17104	ORPHA:93925	Alobar holoprosencephaly		200
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	CDON CL E G H	50937	17104	ORPHA:93924	Lobar holoprosencephaly		200
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	CDON CL E G H	50937	17104	ORPHA:93926	Midline interhemispheric variant of holoprosencephaly		200
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	CDON CL E G H	50937	17104	ORPHA:220386	Semilobar holoprosencephaly		200
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	CEACAM3 CL E G H	1084	1815	ORPHA:586	Cystic fibrosis
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	CEACAM6 CL E G H	4680	1818	ORPHA:586	Cystic fibrosis		1
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	CEP78 CL E G H	84131	25740	ORPHA:231183	Usher syndrome type 3		9
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	CFAP410 CL E G H	755	1260	ORPHA:803	Amyotrophic lateral sclerosis
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	CFTR CL E G H	1080	1884	ORPHA:586	Cystic fibrosis		1371
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	CHCHD10 CL E G H	400916	15559	ORPHA:803	Amyotrophic lateral sclerosis		11
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	CHD7 CL E G H	55636	20626	ORPHA:432	Normosmic congenital hypogonadotropic hypogonadism		515
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	CHD8 CL E G H	57680	20153	OMIM:615032	AUTISM, SUSCEPTIBILITY TO, 18; AUTS18		72
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	CHMP2B CL E G H	25978	24537	ORPHA:803	Amyotrophic lateral sclerosis		42
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	CHMP2B CL E G H	25978	24537	ORPHA:100070	Progressive non-fluent aphasia		42
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	CHRNA2 CL E G H	1135	1956	ORPHA:98784	Autosomal dominant nocturnal frontal lobe epilepsy		188
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	CHRNA4 CL E G H	1137	1958	ORPHA:98784	Autosomal dominant nocturnal frontal lobe epilepsy		225
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	CHRNB2 CL E G H	1141	1962	ORPHA:98784	Autosomal dominant nocturnal frontal lobe epilepsy		88
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	CIB2 CL E G H	10518	24579	ORPHA:231169	Usher syndrome type 1		15
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	CIC CL E G H	23152	14214	OMIM:617600	Mental retardation, autosomal dominant 45		39
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	CIZ1 CL E G H	25792	16744	ORPHA:420492	Adult-onset cervical dystonia, DYT23 type		16
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	CLCA4 CL E G H	22802	2018	ORPHA:586	Cystic fibrosis
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	CLCN3 CL E G H	1182	2021	OMIM:619512	NEURODEVELOPMENTAL DISORDER WITH HYPOTONIA AND BRAIN ABNORMALITIES; NEDHYBA		2
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	CLCN4 CL E G H	1183	2022	ORPHA:485350	CLCN4-related X-linked intellectual disability syndrome		45
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	CLCN4 CL E G H	1183	2022	OMIM:300114	Raynaud-Claes syndrome		45
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	CLIP2 CL E G H	7461	2586	ORPHA:904	Williams syndrome
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	CLN3 CL E G H	1201	2074	OMIM:204200	Ceroid lipofuscinosis, neuronal, 3		216
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	CLN3 CL E G H	1201	2074	ORPHA:228346	CLN3 disease		216
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	CLN5 CL E G H	1203	2076	ORPHA:228360	CLN5 disease		141
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	CLRN1 CL E G H	7401	12605	ORPHA:231183	Usher syndrome type 3		60
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	CLTRN CL E G H	57393	29437	ORPHA:2116	Hartnup disease
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	COL7A1 CL E G H	1294	2214	ORPHA:89842	Autosomal recessive generalized dystrophic epidermolysis bullosa, intermediate form		263
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	COL7A1 CL E G H	1294	2214	ORPHA:79408	Autosomal recessive generalized dystrophic epidermolysis bullosa, severe form		263
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	COMT CL E G H	1312	2228	ORPHA:567	22q11.2 deletion syndrome		6
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	COMT CL E G H	1312	2228	OMIM:167870	Panic disorder 1		6
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	COQ2 CL E G H	27235	25223	ORPHA:227510	Multiple system atrophy, cerebellar type		54
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	COQ2 CL E G H	27235	25223	ORPHA:98933	Multiple system atrophy, parkinsonian type		54
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	COX1 CL E G H	4512	7419	ORPHA:550	MELAS
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	COX2 CL E G H	4513	7421	ORPHA:550	MELAS
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	COX3 CL E G H	4514	7422	ORPHA:550	MELAS
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	CPOX CL E G H	1371	2321	OMIM:121300	Coproporphyria		72
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	CREBBP CL E G H	1387	2348	ORPHA:353281	Rubinstein-Taybi syndrome due to 16p13.3 microdeletion	HP:0040282 - Frequent	291
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	CREBBP CL E G H	1387	2348	ORPHA:353277	Rubinstein-Taybi syndrome due to CREBBP mutations	HP:0040282 - Frequent	291
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	CRH CL E G H	1392	2355	ORPHA:98784	Autosomal dominant nocturnal frontal lobe epilepsy		1
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	CTNNB1 CL E G H	1499	2514	ORPHA:1501	Adrenocortical carcinoma		88
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	DAO CL E G H	1610	2671	ORPHA:803	Amyotrophic lateral sclerosis
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	DCTN1 CL E G H	1639	2711	ORPHA:803	Amyotrophic lateral sclerosis		86
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	DCTN1 CL E G H	1639	2711	OMIM:168605	Perry syndrome		86
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	DCTN4 CL E G H	51164	15518	ORPHA:586	Cystic fibrosis
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	DDB1 CL E G H	1642	2717	OMIM:619426	WHITE-KERNOHAN SYNDROME; WHIKERS
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	DEAF1 CL E G H	10522	14677	ORPHA:819	Smith-Magenis syndrome		33
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	DEPDC5 CL E G H	9681	18423	ORPHA:98784	Autosomal dominant nocturnal frontal lobe epilepsy		172
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	DISP1 CL E G H	84976	19711	ORPHA:93925	Alobar holoprosencephaly		22
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	DISP1 CL E G H	84976	19711	ORPHA:93924	Lobar holoprosencephaly		22
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	DISP1 CL E G H	84976	19711	ORPHA:93926	Midline interhemispheric variant of holoprosencephaly		22
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	DISP1 CL E G H	84976	19711	ORPHA:220386	Semilobar holoprosencephaly		22
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	DLAT CL E G H	1737	2896	ORPHA:79244	Pyruvate dehydrogenase E2 deficiency		82
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	DLL1 CL E G H	28514	2908	ORPHA:93925	Alobar holoprosencephaly		3
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	DLL1 CL E G H	28514	2908	ORPHA:93924	Lobar holoprosencephaly		3
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	DLL1 CL E G H	28514	2908	ORPHA:93926	Midline interhemispheric variant of holoprosencephaly		3
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	DLL1 CL E G H	28514	2908	ORPHA:220386	Semilobar holoprosencephaly		3
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	DLST CL E G H	1743	2911	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	DNAJC30 CL E G H	84277	16410	ORPHA:904	Williams syndrome
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	DNAJC6 CL E G H	9829	15469	ORPHA:2828	Young-onset Parkinson disease		6
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	DNMT3A CL E G H	1788	2978	ORPHA:276621	Sporadic pheochromocytoma/secreting paraganglioma		44
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	DNMT3A CL E G H	1788	2978	ORPHA:404443	Tatton-Brown-Rahman syndrome		44
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	DPH1 CL E G H	1801	3003	ORPHA:459061	Craniofacial dysplasia-short stature-ectodermal anomalies-intellectual disability syndrome		3
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	DRD2 CL E G H	1813	3023	ORPHA:36899	Myoclonus-dystonia syndrome		16
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	DUSP6 CL E G H	1848	3072	ORPHA:432	Normosmic congenital hypogonadotropic hypogonadism		4
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	DYRK1A CL E G H	1859	3091	ORPHA:268261	DYRK1A-related intellectual disability syndrome due to 21q22.13q22.2 microdeletion		134
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	DYRK1A CL E G H	1859	3091	ORPHA:464311	Intellectual disability syndrome due to a DYRK1A point mutation		134
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	EDNRA CL E G H	1909	3179	ORPHA:586	Cystic fibrosis		3
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	EHMT1 CL E G H	79813	24650	ORPHA:96147	Kleefstra syndrome due to 9q34 microdeletion		223
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	EIF2AK1 CL E G H	27102	24921	OMIM:618878	LEUKOENCEPHALOPATHY, MOTOR DELAY, SPASTICITY, AND DYSARTHRIA SYNDROME; LEMSPAD
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	EIF4H CL E G H	7458	12741	ORPHA:904	Williams syndrome
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	ELN CL E G H	2006	3327	ORPHA:904	Williams syndrome		172
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	ELN CL E G H	2006	3327	OMIM:194050	Williams-Beuren syndrome		172
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	EMC10 CL E G H	284361	27609	OMIM:619264	NEURODEVELOPMENTAL DISORDER WITH DYSMORPHIC FACIES AND VARIABLE SEIZURES; NEDDFAS
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	EP300 CL E G H	2033	3373	ORPHA:353284	Rubinstein-Taybi syndrome due to EP300 haploinsufficiency	HP:0040282 - Frequent	250
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	EPAS1 CL E G H	2034	3374	ORPHA:276621	Sporadic pheochromocytoma/secreting paraganglioma		112
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	EPCAM CL E G H	4072	11529	ORPHA:144	Lynch syndrome		170
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	EPHA4 CL E G H	2043	3388	ORPHA:803	Amyotrophic lateral sclerosis		4
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	ERBB4 CL E G H	2066	3432	ORPHA:803	Amyotrophic lateral sclerosis		15
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	ESPN CL E G H	83715	13281	ORPHA:231169	Usher syndrome type 1		33
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	FA2H CL E G H	79152	21197	ORPHA:329308	Fatty acid hydroxylase-associated neurodegeneration		76
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	FAN1 CL E G H	22909	29170	ORPHA:144	Lynch syndrome		15
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	FGF17 CL E G H	8822	3673	ORPHA:432	Normosmic congenital hypogonadotropic hypogonadism		3
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	FGF8 CL E G H	2253	3686	ORPHA:93925	Alobar holoprosencephaly		17
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	FGF8 CL E G H	2253	3686	ORPHA:93924	Lobar holoprosencephaly		17
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	FGF8 CL E G H	2253	3686	ORPHA:93926	Midline interhemispheric variant of holoprosencephaly		17
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	FGF8 CL E G H	2253	3686	ORPHA:432	Normosmic congenital hypogonadotropic hypogonadism		17
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	FGF8 CL E G H	2253	3686	ORPHA:220386	Semilobar holoprosencephaly		17
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	FGFR1 CL E G H	2260	3688	ORPHA:93924	Lobar holoprosencephaly		172
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	FGFR1 CL E G H	2260	3688	ORPHA:432	Normosmic congenital hypogonadotropic hypogonadism		172
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	FGFR1 CL E G H	2260	3688	ORPHA:220386	Semilobar holoprosencephaly		172
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	FH CL E G H	2271	3700	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma		301
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	FIG4 CL E G H	9896	16873	ORPHA:803	Amyotrophic lateral sclerosis		111
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	FIG4 CL E G H	9896	16873	ORPHA:208441	Bilateral parasagittal parieto-occipital polymicrogyria	HP:0040283 - Occasional	111
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	FKBP6 CL E G H	8468	3722	ORPHA:904	Williams syndrome
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	FLII CL E G H	2314	3750	ORPHA:819	Smith-Magenis syndrome
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	FLT4 CL E G H	2324	3767	OMIM:618780	CONGENITAL HEART DEFECTS, MULTIPLE TYPES, 7; CHTD7		90
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	FMO3 CL E G H	2328	3771	ORPHA:468726	Severe primary trimethylaminuria		55
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	FMR1 CL E G H	2332	3775	ORPHA:908	Fragile X syndrome		30
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	FMR1 CL E G H	2332	3775	OMIM:300623	Fragile X tremor/ataxia syndrome		30
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	FMR1 CL E G H	2332	3775	ORPHA:93256	Fragile X-associated tremor/ataxia syndrome		30
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	FMR1 CL E G H	2332	3775	ORPHA:449291	Symptomatic form of fragile X syndrome in female carriers		30
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	FOXH1 CL E G H	8928	3814	ORPHA:93925	Alobar holoprosencephaly		48
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	FOXH1 CL E G H	8928	3814	ORPHA:93924	Lobar holoprosencephaly		48
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	FOXH1 CL E G H	8928	3814	ORPHA:93926	Midline interhemispheric variant of holoprosencephaly		48
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	FOXH1 CL E G H	8928	3814	ORPHA:220386	Semilobar holoprosencephaly		48
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	FOXP1 CL E G H	27086	3823	ORPHA:391372	Intellectual disability-severe speech delay-mild dysmorphism syndrome		184
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	FOXP1 CL E G H	27086	3823	OMIM:613670	Mental retardation with language impairment and with or without autistic features		184
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	FRMD5 CL E G H	84978	28214	OMIM:620094
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	FTSJ1 CL E G H	24140	13254	OMIM:309549	Mental retardation, X-linked 9		13
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	FUS CL E G H	2521	4010	ORPHA:803	Amyotrophic lateral sclerosis		105
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	FUZ CL E G H	80199	26219	ORPHA:1136	Arnold-Chiari malformation type II		3
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	GABBR2 CL E G H	9568	4507	ORPHA:3095	Atypical Rett syndrome		5
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	GABRA1 CL E G H	2554	4075	ORPHA:64280	Childhood absence epilepsy		134
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	GABRA1 CL E G H	2554	4075	ORPHA:33069	Dravet syndrome		134
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	GABRB3 CL E G H	2562	4083	ORPHA:64280	Childhood absence epilepsy		57
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	GABRD CL E G H	2563	4084	ORPHA:36387	Generalized epilepsy with febrile seizures-plus		10
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	GABRG2 CL E G H	2566	4087	ORPHA:64280	Childhood absence epilepsy		139
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	GABRG2 CL E G H	2566	4087	ORPHA:33069	Dravet syndrome		139
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	GABRG2 CL E G H	2566	4087	ORPHA:36387	Generalized epilepsy with febrile seizures-plus		139
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	GABRG2 CL E G H	2566	4087	ORPHA:1945	Rolandic epilepsy		139
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	GALT CL E G H	2592	4135	ORPHA:79239	Classic galactosemia		351
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	GAS1 CL E G H	2619	4165	ORPHA:93925	Alobar holoprosencephaly		2
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	GAS1 CL E G H	2619	4165	ORPHA:93924	Lobar holoprosencephaly		2
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	GAS1 CL E G H	2619	4165	ORPHA:93926	Midline interhemispheric variant of holoprosencephaly		2
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	GAS1 CL E G H	2619	4165	ORPHA:220386	Semilobar holoprosencephaly		2
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	GCH1 CL E G H	2643	4193	ORPHA:98808	Autosomal dominant dopa-responsive dystonia		86
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	GCLC CL E G H	2729	4311	ORPHA:586	Cystic fibrosis		2
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	GLA CL E G H	2717	4296	ORPHA:324	Fabry disease		291
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	GLE1 CL E G H	2733	4315	ORPHA:803	Amyotrophic lateral sclerosis		45
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	GLI2 CL E G H	2736	4318	ORPHA:93925	Alobar holoprosencephaly		173
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	GLI2 CL E G H	2736	4318	ORPHA:93924	Lobar holoprosencephaly		173
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	GLI2 CL E G H	2736	4318	ORPHA:93926	Midline interhemispheric variant of holoprosencephaly		173
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	GLI2 CL E G H	2736	4318	ORPHA:220386	Semilobar holoprosencephaly		173
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	GLT8D1 CL E G H	55830	24870	ORPHA:803	Amyotrophic lateral sclerosis
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	GM2A CL E G H	2760	4367	ORPHA:309246	GM2 gangliosidosis, AB variant	HP:0040281 - Very frequent	69
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	GNA11 CL E G H	2767	4379	ORPHA:428	Autosomal dominant hypocalcemia		16
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	GNAS CL E G H	2778	4392	OMIM:219080	ACTH-independent macronodular adrenal hyperplasia		101
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	GNAS CL E G H	2778	4392	ORPHA:79443	Pseudohypoparathyroidism type 1A		101
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	GNAS CL E G H	2778	4392	ORPHA:94089	Pseudohypoparathyroidism type 1B		101
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	GNAS CL E G H	2778	4392	ORPHA:79444	Pseudohypoparathyroidism type 1C		101
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	GNB1 CL E G H	2782	4396	OMIM:616973	Mental retardation, autosomal dominant 42		12
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	GNRH1 CL E G H	2796	4419	ORPHA:432	Normosmic congenital hypogonadotropic hypogonadism		15
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	GNRHR CL E G H	2798	4421	ORPHA:432	Normosmic congenital hypogonadotropic hypogonadism		92
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	GP1BB CL E G H	2812	4440	ORPHA:567	22q11.2 deletion syndrome		8
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	GPR101 CL E G H	83550	14963	ORPHA:963	Acromegaly		5
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	GRIK2 CL E G H	2898	4580	OMIM:619580	NEURODEVELOPMENTAL DISORDER WITH IMPAIRED LANGUAGE AND ATAXIA AND WITH OR WITHOUT SEIZURES; NEDLAS		32
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	GRIN2A CL E G H	2903	4585	ORPHA:98818	Landau-Kleffner syndrome		434
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	GRIN2A CL E G H	2903	4585	ORPHA:1945	Rolandic epilepsy		434
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	GRN CL E G H	2896	4601	ORPHA:100070	Progressive non-fluent aphasia		126
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	GSTM3 CL E G H	2947	4635	ORPHA:586	Cystic fibrosis		1
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	GTF2I CL E G H	2969	4659	ORPHA:904	Williams syndrome		1
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	GTF2IRD1 CL E G H	9569	4661	ORPHA:904	Williams syndrome		1
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	GTF2IRD2 CL E G H	84163	30775	ORPHA:904	Williams syndrome		1
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	H1-4 CL E G H	3008	4718	OMIM:617537	Rahman syndrome
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	HARS1 CL E G H	3035	4816	ORPHA:231183	Usher syndrome type 3
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	HCN1 CL E G H	348980	4845	ORPHA:36387	Generalized epilepsy with febrile seizures-plus		54
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	HDAC8 CL E G H	55869	13315	ORPHA:199	Cornelia de Lange syndrome		37
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	HEXB CL E G H	3074	4879	ORPHA:309169	Sandhoff disease, adult form		80
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	HFE CL E G H	3077	4886	ORPHA:586	Cystic fibrosis		38
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	HIRA CL E G H	7290	4916	ORPHA:567	22q11.2 deletion syndrome		3
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	HIVEP2 CL E G H	3097	4921	OMIM:616977	Mental retardation, autosomal dominant 43		13
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	HLA-DQA1 CL E G H	3117	4942	OMIM:212750	Celiac disease, susceptibility to, 1
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	HLA-DQB1 CL E G H	3119	4944	OMIM:212750	Celiac disease, susceptibility to, 1
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	HLA-DQB1 CL E G H	3119	4944	OMIM:123400	Creutzfeldt-Jakob disease
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	HMBS CL E G H	3145	4982	ORPHA:79276	Acute intermittent porphyria		81
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	HMBS CL E G H	3145	4982	OMIM:176000	Porphyria, acute intermittent		81
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	HMOX1 CL E G H	3162	5013	ORPHA:586	Cystic fibrosis		3
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	HNRNPA1 CL E G H	3178	5031	ORPHA:803	Amyotrophic lateral sclerosis		31
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	HNRNPH2 CL E G H	3188	5042	OMIM:300986	MENTAL RETARDATION, X-LINKED, SYNDROMIC, BAIN TYPE; MRXSB		3
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	HS6ST1 CL E G H	9394	5201	ORPHA:432	Normosmic congenital hypogonadotropic hypogonadism		8
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	HSPG2 CL E G H	3339	5273	ORPHA:800	Schwartz-Jampel syndrome		345
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	HTR2A CL E G H	3356	5293	OMIM:164230	Obsessive-Compulsive disorder 1		4
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	HTRA1 CL E G H	5654	9476	OMIM:600142	Autosomal recessive cerebral arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL)		34
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	HTRA2 CL E G H	27429	14348	ORPHA:2828	Young-onset Parkinson disease		39
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	HTT CL E G H	3064	4851	ORPHA:399	Huntington disease		12
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	IFNG CL E G H	3458	5438	ORPHA:805	Tuberous sclerosis complex		23
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	IGF1R CL E G H	3480	5465	OMIM:270450	Insulin-Like growth factor I, resistance to		268
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	IMPDH2 CL E G H	3615	6053	ORPHA:98808	Autosomal dominant dopa-responsive dystonia		1
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	IQSEC2 CL E G H	23096	29059	ORPHA:819	Smith-Magenis syndrome		119
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	JMJD1C CL E G H	221037	12313	ORPHA:567	22q11.2 deletion syndrome		2
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	JPH3 CL E G H	57338	14203	OMIM:606438	Huntington disease-like 2		2
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	JRK CL E G H	8629	6199	ORPHA:64280	Childhood absence epilepsy
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	KANSL1 CL E G H	284058	24565	ORPHA:363958	17q21.31 microdeletion syndrome		283
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	KANSL1 CL E G H	284058	24565	OMIM:610443	Koolen-De Vries syndrome		283
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	KANSL1 CL E G H	284058	24565	ORPHA:363965	Koolen-De Vries syndrome due to a point mutation		283
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	KCNN2 CL E G H	3781	6291	OMIM:619725	NEURODEVELOPMENTAL DISORDER WITH OR WITHOUT VARIABLE MOVEMENT OR BEHAVIORAL ABNORMALITIES; NEDMAB
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	KCNN4 CL E G H	3783	6293	ORPHA:586	Cystic fibrosis		3
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	KCNT1 CL E G H	57582	18865	ORPHA:98784	Autosomal dominant nocturnal frontal lobe epilepsy		321
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	KCTD17 CL E G H	79734	25705	OMIM:616398	Dystonia 26, myoclonic		1
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	KCTD17 CL E G H	79734	25705	ORPHA:36899	Myoclonus-dystonia syndrome		1
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	KIF1B CL E G H	23095	16636	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma		202
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	KISS1 CL E G H	3814	6341	ORPHA:432	Normosmic congenital hypogonadotropic hypogonadism		3
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	KISS1R CL E G H	84634	4510	ORPHA:432	Normosmic congenital hypogonadotropic hypogonadism		14
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	KMT2A CL E G H	4297	7132	ORPHA:319182	Wiedemann-Steiner syndrome		91
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	KMT2B CL E G H	9757	15840	ORPHA:589618	Dystonia 28		11
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	KMT2E CL E G H	55904	18541	OMIM:618512	O'donnell-Luria-Rodan syndrome		1
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	KPTN CL E G H	11133	6404	ORPHA:397612	Macrocephaly-developmental delay syndrome		13
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	KPTN CL E G H	11133	6404	OMIM:615637	Mental retardation, autosomal recessive 41		13
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	KRAS CL E G H	3845	6407	ORPHA:144	Lynch syndrome		196
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	LARP7 CL E G H	51574	24912	OMIM:615071	Alazami syndrome		16
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	LARP7 CL E G H	51574	24912	ORPHA:319671	Alazami syndrome		16
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	LGI3 CL E G H	203190	18711	OMIM:620007
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	LIMK1 CL E G H	3984	6613	ORPHA:904	Williams syndrome
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	LRRK2 CL E G H	120892	18618	ORPHA:2828	Young-onset Parkinson disease		221
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	MAMLD1 CL E G H	10046	2568	ORPHA:95706	Non-syndromic posterior hypospadias		5
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	MAN2B1 CL E G H	4125	6826	ORPHA:309288	Alpha-mannosidosis, adult form		136
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	MAN2B1 CL E G H	4125	6826	ORPHA:309282	Alpha-mannosidosis, infantile form		136
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	MAPK1 CL E G H	5594	6871	OMIM:619087	NOONAN SYNDROME 13; NS13		2
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	MAPT CL E G H	4137	6893	ORPHA:100070	Progressive non-fluent aphasia		140
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	MATR3 CL E G H	9782	6912	ORPHA:803	Amyotrophic lateral sclerosis		80
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	MAX CL E G H	4149	6913	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma		84
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	MBD5 CL E G H	55777	20444	OMIM:156200	Mental retardation, autosomal dominant 1		252
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	MDH2 CL E G H	4191	6971	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma		4
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	MECP2 CL E G H	4204	6990	ORPHA:3095	Atypical Rett syndrome		950
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	MECP2 CL E G H	4204	6990	OMIM:300260	Mental retardation, x-linked syndromic, Lubs type		950
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	MECP2 CL E G H	4204	6990	ORPHA:3077	X-linked intellectual disability-psychosis-macroorchidism syndrome	HP:0040283 - Occasional	950
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	MED12L CL E G H	116931	16050	OMIM:618872	NIZON-ISIDOR SYNDROME; NIZIDS
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	MEN1 CL E G H	4221	7010	ORPHA:97279	Insulinoma		462
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	METTL27 CL E G H	155368	19068	ORPHA:904	Williams syndrome		1
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	MIF CL E G H	4282	7097	ORPHA:586	Cystic fibrosis		1
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	MIR17HG CL E G H	407975	23564	ORPHA:391646	Feingold syndrome type 2		1
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	MLH1 CL E G H	4292	7127	ORPHA:144	Lynch syndrome		1819
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	MLH3 CL E G H	27030	7128	ORPHA:144	Lynch syndrome		131
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	MLXIPL CL E G H	51085	12744	ORPHA:904	Williams syndrome		1
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	MLXIPL CL E G H	51085	12744	OMIM:194050	Williams-Beuren syndrome		1
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	MMP1 CL E G H	4312	7155	ORPHA:79408	Autosomal recessive generalized dystrophic epidermolysis bullosa, severe form		6
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	MSH2 CL E G H	4436	7325	ORPHA:144	Lynch syndrome		2162
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	MSH6 CL E G H	2956	7329	ORPHA:144	Lynch syndrome		2232
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	MSTO1 CL E G H	55154	29678	ORPHA:502423	Mitochondrial myopathy-cerebellar ataxia-pigmentary retinopathy syndrome
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	MSTO1 CL E G H	55154	29678	OMIM:617675	Myopathy, mitochondrial, and ataxia
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	MYO7A CL E G H	4647	7606	ORPHA:231169	Usher syndrome type 1		516
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	MYO7A CL E G H	4647	7606	ORPHA:231178	Usher syndrome type 2		516
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	NAGS CL E G H	162417	17996	ORPHA:927	Hyperammonemia due to N-acetylglutamate synthase deficiency		36
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	NCF1 CL E G H	653361	7660	ORPHA:904	Williams syndrome		13
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	ND1 CL E G H	4535	7455	ORPHA:550	MELAS
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	ND4 CL E G H	4538	7459	ORPHA:550	MELAS
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	ND5 CL E G H	4540	7461	ORPHA:550	MELAS
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	ND6 CL E G H	4541	7462	ORPHA:550	MELAS
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	NDP CL E G H	4693	7678	ORPHA:649	Norrie disease		39
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	NEFH CL E G H	4744	7737	ORPHA:803	Amyotrophic lateral sclerosis		24
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	NEK1 CL E G H	4750	7744	ORPHA:803	Amyotrophic lateral sclerosis		101
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	NEXMIF CL E G H	340533	29433	OMIM:300912	Mental retardation, X-linked 98		52
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	NF1 CL E G H	4763	7765	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma		1952
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	NFASC CL E G H	23114	29866	OMIM:618356	Neurodevelopmental disorder with central and peripheral motor dysfunction
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	NFIB CL E G H	4781	7785	OMIM:618286	Macrocephaly, acquired, with impaired intellectual development		1
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	NFIX CL E G H	4784	7788	ORPHA:420179	Malan overgrowth syndrome		40
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	NFIX CL E G H	4784	7788	OMIM:614753	Sotos syndrome 2		40
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	NIPBL CL E G H	25836	28862	ORPHA:199	Cornelia de Lange syndrome		494
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	NKX2-1 CL E G H	7080	11825	OMIM:118700	Chorea, benign hereditary		51
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	NODAL CL E G H	4838	7865	ORPHA:93925	Alobar holoprosencephaly		45
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	NODAL CL E G H	4838	7865	ORPHA:93924	Lobar holoprosencephaly		45
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	NODAL CL E G H	4838	7865	ORPHA:93926	Midline interhemispheric variant of holoprosencephaly		45
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	NODAL CL E G H	4838	7865	ORPHA:220386	Semilobar holoprosencephaly		45
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	NONO CL E G H	4841	7871	ORPHA:466791	Macrocephaly-intellectual disability-left ventricular non compaction syndrome		10
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	NOTCH3 CL E G H	4854	7883	ORPHA:136	Cerebral autosomal dominant arteriopathy-subcortical infarcts-leukoencephalopathy		144
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	NR3C1 CL E G H	2908	7978	ORPHA:96253	Cushing disease		79
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	NR3C1 CL E G H	2908	7978	OMIM:615962	Glucocorticoid resistance, generalized		79
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	NR4A2 CL E G H	4929	7981	ORPHA:98808	Autosomal dominant dopa-responsive dystonia		27
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	NSD1 CL E G H	64324	14234	ORPHA:821	Sotos syndrome		544
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	NSD2 CL E G H	7468	12766	OMIM:619695	RAUCH-STEINDL SYNDROME; RAUST		118
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	NSMF CL E G H	26012	29843	ORPHA:432	Normosmic congenital hypogonadotropic hypogonadism		6
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	NTNG1 CL E G H	22854	23319	ORPHA:3095	Atypical Rett syndrome		1
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	OCRL CL E G H	4952	8108	ORPHA:534	Oculocerebrorenal syndrome of Lowe		88
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	OPTN CL E G H	10133	17142	ORPHA:803	Amyotrophic lateral sclerosis		62
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	PAK3 CL E G H	5063	8592	OMIM:300558	MENTAL RETARDATION, X-LINKED 30; MRX30		27
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	PARK7 CL E G H	11315	16369	OMIM:606324	PARKINSON DISEASE 7, AUTOSOMAL RECESSIVE EARLY-ONSET; PARK7		23
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	PARK7 CL E G H	11315	16369	ORPHA:2828	Young-onset Parkinson disease		23
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	PCDH15 CL E G H	65217	14674	ORPHA:231169	Usher syndrome type 1		352
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	PCDH19 CL E G H	57526	14270	ORPHA:33069	Dravet syndrome		225
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	PCDH19 CL E G H	57526	14270	ORPHA:101039	Female restricted epilepsy with intellectual disability		225
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	PDE10A CL E G H	10846	8772	ORPHA:494541	Childhood-onset benign chorea with striatal involvement		5
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	PDE11A CL E G H	50940	8773	OMIM:610475	Pigmented nodular adrenocortical disease, primary, 2		13
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	PDGFB CL E G H	5155	8800	OMIM:615483	Basal ganglia calcification, idiopathic, 5		9
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	PDGFRB CL E G H	5159	8804	OMIM:616592	Kosaki overgrowth syndrome		28
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	PDZD7 CL E G H	79955	26257	ORPHA:231178	Usher syndrome type 2		40
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	PFN1 CL E G H	5216	8881	ORPHA:803	Amyotrophic lateral sclerosis		6
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	PHF21A CL E G H	51317	24156	OMIM:618725	INTELLECTUAL DEVELOPMENTAL DISORDER WITH BEHAVIORAL ABNORMALITIES AND CRANIOFACIAL DYSMORPHISM WITH OR WITHOUT SEIZURES; IDDBCS		2
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	PHIP CL E G H	55023	15673	OMIM:617991	Developmental delay, intellectual disability, obesity, and dysmorphic features		11
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	PIK3CA CL E G H	5290	8975	ORPHA:144	Lynch syndrome		162
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	PINK1 CL E G H	65018	14581	OMIM:605909	Parkinson disease 6, autosomal recessive early-onset		55
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	PINK1 CL E G H	65018	14581	ORPHA:2828	Young-onset Parkinson disease		55
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	PLCH1 CL E G H	23007	29185	ORPHA:93925	Alobar holoprosencephaly
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	PMS1 CL E G H	5378	9121	ORPHA:144	Lynch syndrome		56
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	PMS2 CL E G H	5395	9122	ORPHA:144	Lynch syndrome		1121
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	PODXL CL E G H	5420	9171	ORPHA:2828	Young-onset Parkinson disease		6
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	POGZ CL E G H	23126	18801	OMIM:616364	White-Sutton syndrome		35
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	POLG CL E G H	5428	9179	ORPHA:254892	Autosomal dominant progressive external ophthalmoplegia		464
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	POLG2 CL E G H	11232	9180	ORPHA:254892	Autosomal dominant progressive external ophthalmoplegia		45
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	POLG2 CL E G H	11232	9180	OMIM:619425	MITOCHONDRIAL DNA DEPLETION SYNDROME 16B (NEUROOPHTHALMIC TYPE); MTDPS16B		45
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	PON1 CL E G H	5444	9204	ORPHA:803	Amyotrophic lateral sclerosis		4
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	PON2 CL E G H	5445	9205	ORPHA:803	Amyotrophic lateral sclerosis		2
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	PON3 CL E G H	5446	9206	ORPHA:803	Amyotrophic lateral sclerosis		1
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	PPARGC1A CL E G H	10891	9237	ORPHA:803	Amyotrophic lateral sclerosis		1
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	PPM1D CL E G H	8493	9277	OMIM:617450	Intellectual developmental disorder with gastrointestinal difficulties and high pain threshold		22
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	PPOX CL E G H	5498	9280	ORPHA:79473	Porphyria variegata		41
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	PPP1CB CL E G H	5500	9282	OMIM:617506	Noonan syndrome-like disorder with loose anagen hair 2		9
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	PPP2R2B CL E G H	5521	9305	OMIM:604326	Spinocerebellar ataxia 12		5
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	PQBP1 CL E G H	10084	9330	OMIM:309500	Renpenning syndrome		28
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	PRKAR1A CL E G H	5573	9388	ORPHA:1501	Adrenocortical carcinoma		134
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	PRKAR1A CL E G H	5573	9388	OMIM:610489	Pigmented nodular adrenocortical disease, primary, 1		134
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	PRKAR1B CL E G H	5575	9390	ORPHA:412066	PRKAR1B-related neurodegenerative dementia with intermediate filaments		2
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	PRKN CL E G H	5071	8607	ORPHA:2828	Young-onset Parkinson disease		138
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	PRNP CL E G H	5621	9449	OMIM:123400	Creutzfeldt-Jakob disease		69
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	PRNP CL E G H	5621	9449	ORPHA:280397	Familial Alzheimer-like prion disease		69
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	PRNP CL E G H	5621	9449	OMIM:603218	Huntington disease-like 1		69
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	PRNP CL E G H	5621	9449	ORPHA:282166	Inherited Creutzfeldt-Jakob disease		69
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	PROK2 CL E G H	60675	18455	ORPHA:432	Normosmic congenital hypogonadotropic hypogonadism		9
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	PROKR2 CL E G H	128674	15836	ORPHA:432	Normosmic congenital hypogonadotropic hypogonadism		34
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	PRPH CL E G H	5630	9461	ORPHA:803	Amyotrophic lateral sclerosis		25
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	PRR12 CL E G H	57479	29217	OMIM:619539	NEUROOCULAR SYNDROME; NOC		1
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	PRRT2 CL E G H	112476	30500	OMIM:602066	Convulsions, familial infantile, with paroxysmal choreoathetosis		94
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	PSEN1 CL E G H	5663	9508	ORPHA:100070	Progressive non-fluent aphasia		241
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	PSMD12 CL E G H	5718	9557	ORPHA:529962	17q24.2 microdeletion syndrome		4
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	PTCH1 CL E G H	5727	9585	ORPHA:93925	Alobar holoprosencephaly		665
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	PTCH1 CL E G H	5727	9585	ORPHA:93924	Lobar holoprosencephaly		665
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	PTCH1 CL E G H	5727	9585	ORPHA:93926	Midline interhemispheric variant of holoprosencephaly		665
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	PTCH1 CL E G H	5727	9585	ORPHA:220386	Semilobar holoprosencephaly		665
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	PURA CL E G H	5813	9701	ORPHA:438216	PURA-related severe neonatal hypotonia-seizures-encephalopathy syndrome due to a point mutation		53
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	RAD21 CL E G H	5885	9811	ORPHA:199	Cornelia de Lange syndrome		25
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	RAI1 CL E G H	10743	9834	ORPHA:1713	17p11.2 microduplication syndrome		150
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	RAI1 CL E G H	10743	9834	ORPHA:819	Smith-Magenis syndrome		150
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	RET CL E G H	5979	9967	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma		572
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	RET CL E G H	5979	9967	ORPHA:276621	Sporadic pheochromocytoma/secreting paraganglioma		572
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	RFC2 CL E G H	5982	9970	ORPHA:904	Williams syndrome
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	RIMS2 CL E G H	9699	17283	OMIM:618970	CONE-ROD SYNAPTIC DISORDER SYNDROME, CONGENITAL NONPROGRESSIVE; CRSDS		2
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	RLIM CL E G H	51132	13429	OMIM:300978	Tonne-Kalscheuer syndrome		7
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	RNF125 CL E G H	54941	21150	OMIM:616260	Tenorio syndrome		5
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	RPS20 CL E G H	6224	10405	ORPHA:440437	Familial colorectal cancer Type X		1
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	RREB1 CL E G H	6239	10449	ORPHA:567	22q11.2 deletion syndrome
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	RRM2B CL E G H	50484	17296	ORPHA:254892	Autosomal dominant progressive external ophthalmoplegia		125
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	RRM2B CL E G H	50484	17296	OMIM:613077	Progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal dominant 5		125
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SATB2 CL E G H	23314	21637	ORPHA:251019	2q32q33 microdeletion syndrome		34
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SCN1A CL E G H	6323	10585	ORPHA:33069	Dravet syndrome		1053
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SCN1A CL E G H	6323	10585	ORPHA:36387	Generalized epilepsy with febrile seizures-plus		1053
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SCN1B CL E G H	6324	10586	ORPHA:33069	Dravet syndrome		126
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SCN1B CL E G H	6324	10586	ORPHA:36387	Generalized epilepsy with febrile seizures-plus		126
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SCN2A CL E G H	6326	10588	ORPHA:33069	Dravet syndrome		427
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SCN2A CL E G H	6326	10588	ORPHA:36387	Generalized epilepsy with febrile seizures-plus		427
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SCN9A CL E G H	6335	10597	ORPHA:33069	Dravet syndrome		318
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SCN9A CL E G H	6335	10597	ORPHA:36387	Generalized epilepsy with febrile seizures-plus		318
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SDHA CL E G H	6389	10680	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma		304
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SDHAF2 CL E G H	54949	26034	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma		55
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SDHB CL E G H	6390	10681	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma		237
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SDHB CL E G H	6390	10681	OMIM:115310	Paragangliomas 4		237
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SDHB CL E G H	6390	10681	ORPHA:276621	Sporadic pheochromocytoma/secreting paraganglioma		237
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SDHC CL E G H	6391	10682	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma		147
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SDHC CL E G H	6391	10682	OMIM:605373	Paragangliomas 3		147
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SDHD CL E G H	6392	10683	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma		129
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SDHD CL E G H	6392	10683	OMIM:168000	Paragangliomas 1		129
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SDHD CL E G H	6392	10683	ORPHA:276621	Sporadic pheochromocytoma/secreting paraganglioma		129
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SEC24C CL E G H	9632	10705	ORPHA:567	22q11.2 deletion syndrome
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SEMA4A CL E G H	64218	10729	ORPHA:440437	Familial colorectal cancer Type X		48
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SERPINA1 CL E G H	5265	8941	ORPHA:586	Cystic fibrosis		131
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SETBP1 CL E G H	26040	15573	OMIM:616078	Mental retardation, autosomal dominant 29		143
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SETD1A CL E G H	9739	29010	OMIM:619056	NEURODEVELOPMENTAL DISORDER WITH SPEECH IMPAIRMENT AND DYSMORPHIC FACIES; NEDSID		6
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SETD1B CL E G H	23067	29187	OMIM:619000	INTELLECTUAL DEVELOPMENTAL DISORDER WITH SEIZURES AND LANGUAGE DELAY; IDDSELD
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SETD2 CL E G H	29072	18420	OMIM:616831	Luscan-Lumish syndrome		60
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SETD2 CL E G H	29072	18420	ORPHA:821	Sotos syndrome		60
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SETD5 CL E G H	55209	25566	ORPHA:404440	Intellectual disability-facial dysmorphism syndrome due to SETD5 haploinsufficiency		43
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SGCE CL E G H	8910	10808	OMIM:159900	Dystonia 11, myoclonic		49
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SGCE CL E G H	8910	10808	ORPHA:36899	Myoclonus-dystonia syndrome		49
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SHH CL E G H	6469	10848	ORPHA:93925	Alobar holoprosencephaly		67
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SHH CL E G H	6469	10848	ORPHA:93924	Lobar holoprosencephaly		67
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SHH CL E G H	6469	10848	ORPHA:93926	Midline interhemispheric variant of holoprosencephaly		67
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SHH CL E G H	6469	10848	ORPHA:220386	Semilobar holoprosencephaly		67
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SHQ1 CL E G H	55164	25543	OMIM:619922
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SIN3A CL E G H	25942	19353	OMIM:613406	Witteveen-Kolk syndrome		9
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SIX3 CL E G H	6496	10889	ORPHA:93925	Alobar holoprosencephaly		32
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SIX3 CL E G H	6496	10889	ORPHA:93924	Lobar holoprosencephaly		32
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SIX3 CL E G H	6496	10889	ORPHA:93926	Midline interhemispheric variant of holoprosencephaly		32
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SIX3 CL E G H	6496	10889	ORPHA:220386	Semilobar holoprosencephaly		32
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SLC11A1 CL E G H	6556	10907	ORPHA:586	Cystic fibrosis		2
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SLC25A11 CL E G H	8402	10981	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SLC25A4 CL E G H	291	10990	ORPHA:254892	Autosomal dominant progressive external ophthalmoplegia		68
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SLC26A9 CL E G H	115019	14469	ORPHA:586	Cystic fibrosis		5
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SLC2A1 CL E G H	6513	11005	ORPHA:64280	Childhood absence epilepsy		255
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SLC2A3 CL E G H	6515	11007	ORPHA:399	Huntington disease		1
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SLC35C1 CL E G H	55343	20197	OMIM:266265	Congenital disorder of glycosylation, type IIc		71
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SLC45A1 CL E G H	50651	17939	OMIM:617532	Intellectual developmental disorder with neuropsychiatric features		2
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SLC6A14 CL E G H	11254	11047	ORPHA:586	Cystic fibrosis
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SLC6A19 CL E G H	340024	27960	ORPHA:2116	Hartnup disease		12
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SLC6A4 CL E G H	6532	11050	OMIM:164230	Obsessive-Compulsive disorder 1		52
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SLC7A6OS CL E G H	84138	25807	OMIM:619191	EPILEPSY, PROGRESSIVE MYOCLONIC, 12; EPM12
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SLC9A3 CL E G H	6550	11073	ORPHA:586	Cystic fibrosis		7
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SMC1A CL E G H	8243	11111	ORPHA:3095	Atypical Rett syndrome		135
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SMC1A CL E G H	8243	11111	ORPHA:199	Cornelia de Lange syndrome		135
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SMC1A CL E G H	8243	11111	ORPHA:220386	Semilobar holoprosencephaly		135
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SMC3 CL E G H	9126	2468	ORPHA:199	Cornelia de Lange syndrome		91
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SNCA CL E G H	6622	11138	ORPHA:2828	Young-onset Parkinson disease		65
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SNRPN CL E G H	6638	11164	ORPHA:177907	Prader-Willi syndrome due to translocation		37
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SOD1 CL E G H	6647	11179	ORPHA:803	Amyotrophic lateral sclerosis		53
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SOX5 CL E G H	6660	11201	ORPHA:313892	Developmental and speech delay due to SOX5 deficiency		11
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SOX5 CL E G H	6660	11201	OMIM:616803	Lamb-Shaffer syndrome		11
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SPART CL E G H	23111	18514	ORPHA:101000	Autosomal recessive spastic paraplegia type 20		66
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SPECC1L CL E G H	23384	29022	OMIM:145420	Hypertelorism, Teebi type		6
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SPRY4 CL E G H	81848	15533	ORPHA:432	Normosmic congenital hypogonadotropic hypogonadism		5
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SPTBN1 CL E G H	6711	11275	OMIM:619475	DEVELOPMENTAL DELAY, IMPAIRED SPEECH, AND BEHAVIORAL ABNORMALITIES; DDISBA
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SQSTM1 CL E G H	8878	11280	ORPHA:803	Amyotrophic lateral sclerosis		62
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SRCAP CL E G H	10847	16974	ORPHA:2044	Floating-Harbor syndrome		138
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SRPX2 CL E G H	27286	30668	ORPHA:1945	Rolandic epilepsy		50
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	STAG2 CL E G H	10735	11355	ORPHA:93925	Alobar holoprosencephaly		1
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	STAG2 CL E G H	10735	11355	ORPHA:220386	Semilobar holoprosencephaly		1
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	STAG2 CL E G H	10735	11355	ORPHA:521258	Xq25 microduplication syndrome		1
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	STEEP1 CL E G H	63932	26239	OMIM:301013	MENTAL RETARDATION, X-LINKED 107; MRX107
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	STIL CL E G H	6491	10879	ORPHA:93925	Alobar holoprosencephaly		99
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	STIL CL E G H	6491	10879	ORPHA:93924	Lobar holoprosencephaly		99
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	STIL CL E G H	6491	10879	ORPHA:93926	Midline interhemispheric variant of holoprosencephaly		99
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	STIL CL E G H	6491	10879	ORPHA:220386	Semilobar holoprosencephaly		99
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	STUB1 CL E G H	10273	11427	OMIM:618093	SPINOCEREBELLAR ATAXIA 48; SCA48		14
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	STX16 CL E G H	8675	11431	ORPHA:94089	Pseudohypoparathyroidism type 1B		86
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	STX1A CL E G H	6804	11433	ORPHA:586	Cystic fibrosis
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	STX1A CL E G H	6804	11433	ORPHA:904	Williams syndrome
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	STX1B CL E G H	112755	18539	ORPHA:36387	Generalized epilepsy with febrile seizures-plus		9
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	SYNJ1 CL E G H	8867	11503	ORPHA:2828	Young-onset Parkinson disease		9
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	TAC3 CL E G H	6866	11521	ORPHA:432	Normosmic congenital hypogonadotropic hypogonadism		6
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	TACR3 CL E G H	6870	11528	ORPHA:432	Normosmic congenital hypogonadotropic hypogonadism		34
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	TAF1 CL E G H	6872	11535	OMIM:300966	MENTAL RETARDATION, X-LINKED, SYNDROMIC 33; MRXS33		21
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	TAF15 CL E G H	8148	11547	ORPHA:803	Amyotrophic lateral sclerosis
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	TANC2 CL E G H	26115	30212	OMIM:618906	INTELLECTUAL DEVELOPMENTAL DISORDER WITH AUTISTIC FEATURES AND LANGUAGE DELAY, WITH OR WITHOUT SEIZURES; IDDALDS
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	TARDBP CL E G H	23435	11571	ORPHA:803	Amyotrophic lateral sclerosis		65
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	TBK1 CL E G H	29110	11584	ORPHA:803	Amyotrophic lateral sclerosis		20
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	TBL2 CL E G H	26608	11586	ORPHA:904	Williams syndrome
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	TBX1 CL E G H	6899	11592	ORPHA:567	22q11.2 deletion syndrome		32
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	TBX1 CL E G H	6899	11592	ORPHA:1727	22q11.2 duplication syndrome		32
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	TCF12 CL E G H	6938	11623	OMIM:619718	HYPOGONADOTROPIC HYPOGONADISM 26 WITH OR WITHOUT ANOSMIA; HH26		28
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	TCF20 CL E G H	6942	11631	OMIM:618430	Developmental delay with variable intellectual impairment and behavioral abnormalities		1
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	TDGF1 CL E G H	6997	11701	ORPHA:93925	Alobar holoprosencephaly		1
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	TDGF1 CL E G H	6997	11701	ORPHA:93924	Lobar holoprosencephaly		1
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	TDGF1 CL E G H	6997	11701	ORPHA:93926	Midline interhemispheric variant of holoprosencephaly		1
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	TDGF1 CL E G H	6997	11701	ORPHA:220386	Semilobar holoprosencephaly		1
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	TERT CL E G H	7015	11730	ORPHA:1501	Adrenocortical carcinoma		238
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	TET3 CL E G H	200424	28313	OMIM:618798	BECK-FAHRNER SYNDROME; BEFAHRS
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	TGFB1 CL E G H	7040	11766	ORPHA:586	Cystic fibrosis		13
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	TGFBR2 CL E G H	7048	11773	ORPHA:144	Lynch syndrome		253
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	TGIF1 CL E G H	7050	11776	ORPHA:93925	Alobar holoprosencephaly		32
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	TGIF1 CL E G H	7050	11776	ORPHA:93924	Lobar holoprosencephaly		32
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	TGIF1 CL E G H	7050	11776	ORPHA:93926	Midline interhemispheric variant of holoprosencephaly		32
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	TGIF1 CL E G H	7050	11776	ORPHA:220386	Semilobar holoprosencephaly		32
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	THOC2 CL E G H	57187	19073	OMIM:300957	Mental retardation, X-linked 12/35		5
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	THOC2 CL E G H	57187	19073	ORPHA:457240	X-linked intellectual disability-short stature-overweight syndrome		5
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	TLK2 CL E G H	11011	11842	OMIM:618050	Mental retardation, autosomal dominant 57		1
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	TLR7 CL E G H	51284	15631	OMIM:301080
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	TMCO1 CL E G H	54499	18188	OMIM:213980	Craniofacial dysmorphism, skeletal anomalies, and mental retardation syndrome		6
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	TMEM106B CL E G H	54664	22407	ORPHA:100070	Progressive non-fluent aphasia
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	TMEM127 CL E G H	55654	26038	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma		131
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	TMEM147 CL E G H	10430	30414	OMIM:620075
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	TMEM270 CL E G H	135886	23018	ORPHA:904	Williams syndrome
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	TOR1A CL E G H	1861	3098	ORPHA:36899	Myoclonus-dystonia syndrome		47
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	TP53 CL E G H	7157	11998	ORPHA:1501	Adrenocortical carcinoma		911
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	TP53 CL E G H	7157	11998	ORPHA:96253	Cushing disease		911
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	TREM2 CL E G H	54209	17761	ORPHA:803	Amyotrophic lateral sclerosis		31
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	TREM2 CL E G H	54209	17761	ORPHA:100070	Progressive non-fluent aphasia		31
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	TREX1 CL E G H	11277	12269	ORPHA:247691	Retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations		56
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	TRIP12 CL E G H	9320	12306	OMIM:617752	Mental retardation, autosomal dominant 49		2
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	TRNF CL E G H	4558	7481	ORPHA:550	MELAS
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	TRNH CL E G H	4564	7487	ORPHA:550	MELAS
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	TRNL1 CL E G H	4567	7490	ORPHA:550	MELAS
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	TRNQ CL E G H	4572	7495	ORPHA:550	MELAS
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	TRNS1 CL E G H	4574	7497	ORPHA:550	MELAS
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	TRNS2 CL E G H	4575	7498	ORPHA:550	MELAS
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	TRNS2 CL E G H	4575	7498	ORPHA:231183	Usher syndrome type 3
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	TRNW CL E G H	4578	7501	ORPHA:550	MELAS
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	TSC1 CL E G H	7248	12362	ORPHA:805	Tuberous sclerosis complex		1090
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	TSC2 CL E G H	7249	12363	ORPHA:805	Tuberous sclerosis complex		2738
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	TTC19 CL E G H	54902	26006	OMIM:615157	Mitochondrial complex III deficiency, nuclear type 2		88
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	TWNK CL E G H	56652	1160	ORPHA:254892	Autosomal dominant progressive external ophthalmoplegia		113
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	UBQLN2 CL E G H	29978	12509	ORPHA:803	Amyotrophic lateral sclerosis		20
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	UCHL1 CL E G H	7345	12513	ORPHA:2828	Young-onset Parkinson disease		21
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	UFD1 CL E G H	7353	12520	ORPHA:567	22q11.2 deletion syndrome
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	UNC13A CL E G H	23025	23150	ORPHA:803	Amyotrophic lateral sclerosis		1
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	UQCRC1 CL E G H	7384	12585	OMIM:619279	PARKINSONISM WITH POLYNEUROPATHY; PKNPY
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	USH1C CL E G H	10083	12597	ORPHA:231169	Usher syndrome type 1		173
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	USH1G CL E G H	124590	16356	ORPHA:231169	Usher syndrome type 1		78
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	USH2A CL E G H	7399	12601	ORPHA:231178	Usher syndrome type 2		777
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	USP48 CL E G H	84196	18533	ORPHA:96253	Cushing disease		1
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	USP8 CL E G H	9101	12631	ORPHA:96253	Cushing disease		7
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	USP8 CL E G H	9101	12631	OMIM:219090	Pituitary adenoma 4, ACTH-secreting, somatic	.	7
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	VAPB CL E G H	9217	12649	ORPHA:803	Amyotrophic lateral sclerosis		116
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	VCP CL E G H	7415	12666	ORPHA:329478	Adult-onset distal myopathy due to VCP mutation		63
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	VCP CL E G H	7415	12666	ORPHA:803	Amyotrophic lateral sclerosis		63
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	VCP CL E G H	7415	12666	ORPHA:100070	Progressive non-fluent aphasia		63
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	VHL CL E G H	7428	12687	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma		490
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	VHL CL E G H	7428	12687	ORPHA:276621	Sporadic pheochromocytoma/secreting paraganglioma		490
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	VHL CL E G H	7428	12687	ORPHA:892	Von Hippel-Lindau disease		490
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	VPS13A CL E G H	23230	1908	ORPHA:2388	Choreoacanthocytosis		130
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	VPS13A CL E G H	23230	1908	OMIM:200150	CHOREOACANTHOCYTOSIS		130
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	VPS13C CL E G H	54832	23594	ORPHA:2828	Young-onset Parkinson disease		8
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	VPS37D CL E G H	155382	18287	ORPHA:904	Williams syndrome
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	WAC CL E G H	51322	17327	OMIM:616708	Desanto-Shinawi syndrome		20
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	WAC CL E G H	51322	17327	ORPHA:284169	Facial dysmorphism-developmental delay-behavioral abnormalities syndrome due to 10p11.21p12.31 microdeletion		20
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	WAC CL E G H	51322	17327	ORPHA:466950	Facial dysmorphism-developmental delay-behavioral abnormalities syndrome due to WAC point mutation		20
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	WARS2 CL E G H	10352	12730	OMIM:619738	PARKINSONISM-DYSTONIA 3, CHILDHOOD-ONSET; PKDYS3		2
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	WDR11 CL E G H	55717	13831	ORPHA:432	Normosmic congenital hypogonadotropic hypogonadism		10
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	WFS1 CL E G H	7466	12762	ORPHA:411590	Wolfram-like syndrome		389
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	WFS1 CL E G H	7466	12762	OMIM:614296	Wolfram-Like syndrome, autosomal dominant		389
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	WHRN CL E G H	25861	16361	ORPHA:231178	Usher syndrome type 2		155
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	XK CL E G H	7504	12811	OMIM:300842	Mcleod syndrome		8
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	YWHAG CL E G H	7532	12852	OMIM:617665	Epileptic encephalopathy, early infantile, 56
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	YY1 CL E G H	7528	12856	OMIM:617557	Gabriele-De vries syndrome		7
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	YY1 CL E G H	7528	12856	ORPHA:506358	Gabriele-de Vries syndrome		7
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	YY1 CL E G H	7528	12856	ORPHA:97279	Insulinoma		7
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	ZBTB20 CL E G H	26137	13503	OMIM:259050	Primrose syndrome		17
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	ZIC2 CL E G H	7546	12873	ORPHA:93925	Alobar holoprosencephaly		34
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	ZIC2 CL E G H	7546	12873	ORPHA:93924	Lobar holoprosencephaly		34
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	ZIC2 CL E G H	7546	12873	ORPHA:93926	Midline interhemispheric variant of holoprosencephaly		34
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	ZIC2 CL E G H	7546	12873	ORPHA:220386	Semilobar holoprosencephaly		34
HP:0100852	HP:0100852	Abnormal fear/anxiety-related behavior	0	ZNRF3 CL E G H	84133	18126	ORPHA:1501	Adrenocortical carcinoma
HP:0100852	HP:0033845	Sense of impending doom	1	CL E G H
HP:0100852	HP:0025253	Claustrophobia	1	CL E G H
HP:0100852	HP:0000739	Anxiety	1	ABCC9 CL E G H	10060	60	OMIM:619719	INTELLECTUAL DISABILITY AND MYOPATHY SYNDROME; IDMYS		254
HP:0100852	HP:0000739	Anxiety	1	ACSL4 CL E G H	2182	3571	OMIM:300387	MENTAL RETARDATION, X-LINKED 63; MRX63		19
HP:0100852	HP:0000739	Anxiety	1	ADCY5 CL E G H	111	236	OMIM:606703	Dyskinesia, familial, with facial myokymia	.	25
HP:0100852	HP:0000739	Anxiety	1	ADCY5 CL E G H	111	236	OMIM:619651	NEURODEVELOPMENTAL DISORDER WITH HYPERKINETIC MOVEMENTS AND DYSKINESIA; NEDHYD		25
HP:0100852	HP:0000739	Anxiety	1	ADGRV1 CL E G H	84059	17416	ORPHA:36387	Generalized epilepsy with febrile seizures-plus	HP:0040284 - Very rare	530
HP:0100852	HP:0000739	Anxiety	1	ADGRV1 CL E G H	84059	17416	ORPHA:231178	Usher syndrome type 2	HP:0040283 - Occasional	530
HP:0100852	HP:0000739	Anxiety	1	ADNP CL E G H	23394	15766	ORPHA:404448	ADNP syndrome	HP:0040282 - Frequent	47
HP:0100852	HP:0000739	Anxiety	1	AIP CL E G H	9049	358	ORPHA:963	Acromegaly	HP:0040282 - Frequent	95
HP:0100852	HP:0000739	Anxiety	1	ALAD CL E G H	210	395	ORPHA:100924	Porphyria due to ALA dehydratase deficiency	HP:0040283 - Occasional	62
HP:0100852	HP:0000739	Anxiety	1	ALDH4A1 CL E G H	8659	406	ORPHA:79101	Hyperprolinemia type 2	HP:0040283 - Occasional	74
HP:0100852	HP:0000739	Anxiety	1	ALDH5A1 CL E G H	7915	408	OMIM:271980	Succinic semialdehyde dehydrogenase deficiency	.	108
HP:0100852	HP:0000739	Anxiety	1	ALG14 CL E G H	199857	28287	OMIM:619031	INTELLECTUAL DEVELOPMENTAL DISORDER WITH EPILEPSY, BEHAVIORAL ABNORMALITIES, AND COARSE FACIES; IDDEBF		12
HP:0100852	HP:0000739	Anxiety	1	ANG CL E G H	283	483	ORPHA:803	Amyotrophic lateral sclerosis	HP:0040282 - Frequent	32
HP:0100852	HP:0000739	Anxiety	1	ANXA11 CL E G H	311	535	ORPHA:803	Amyotrophic lateral sclerosis	HP:0040282 - Frequent
HP:0100852	HP:0000739	Anxiety	1	AP1G1 CL E G H	164	555	OMIM:619467	USMANI-RIAZUDDIN SYNDROME, AUTOSOMAL DOMINANT; USRISD
HP:0100852	HP:0000739	Anxiety	1	APC2 CL E G H	10297	24036	ORPHA:821	Sotos syndrome	HP:0040283 - Occasional	1
HP:0100852	HP:0000739	Anxiety	1	AR CL E G H	367	644	ORPHA:95706	Non-syndromic posterior hypospadias	HP:0040283 - Occasional	125
HP:0100852	HP:0000739	Anxiety	1	ARID2 CL E G H	196528	18037	OMIM:617808	Coffin-siris syndrome 6		25
HP:0100852	HP:0000739	Anxiety	1	ARSG CL E G H	22901	24102	ORPHA:231183	Usher syndrome type 3	HP:0040283 - Occasional
HP:0100852	HP:0000739	Anxiety	1	ARVCF CL E G H	421	728	ORPHA:567	22q11.2 deletion syndrome	HP:0040283 - Occasional	1
HP:0100852	HP:0000739	Anxiety	1	ASH1L CL E G H	55870	19088	OMIM:617796	Mental retardation, autosomal dominant 52	.	1
HP:0100852	HP:0000739	Anxiety	1	ATP1A3 CL E G H	478	801	OMIM:128235	Dystonia 12	.	150
HP:0100852	HP:0000739	Anxiety	1	ATP1A3 CL E G H	478	801	ORPHA:71517	Rapid-onset dystonia-parkinsonism	HP:0040283 - Occasional	150
HP:0100852	HP:0025269	Panic attack	1	ATRX CL E G H	546	886	ORPHA:96253	Cushing disease		169
HP:0100852	HP:0000739	Anxiety	1	ATXN2 CL E G H	6311	10555	ORPHA:803	Amyotrophic lateral sclerosis	HP:0040282 - Frequent	11
HP:0100852	HP:0000739	Anxiety	1	BAZ1B CL E G H	9031	961	ORPHA:904	Williams syndrome	HP:0040281 - Very frequent
HP:0100852	HP:0000739	Anxiety	1	BCL11B CL E G H	64919	13222	OMIM:618092	INTELLECTUAL DEVELOPMENTAL DISORDER WITH SPEECH DELAY, DYSMORPHIC FACIES, AND T-CELL ABNORMALITIES	.	3
HP:0100852	HP:0000739	Anxiety	1	BCL7B CL E G H	9275	1005	ORPHA:904	Williams syndrome	HP:0040281 - Very frequent
HP:0100852	HP:0000739	Anxiety	1	BMPR1A CL E G H	657	1076	ORPHA:440437	Familial colorectal cancer Type X	HP:0040282 - Frequent	385
HP:0100852	HP:0000739	Anxiety	1	BPTF CL E G H	2186	3581	ORPHA:529962	17q24.2 microdeletion syndrome	HP:0040282 - Frequent	2
HP:0100852	HP:0025269	Panic attack	1	BRAF CL E G H	673	1097	ORPHA:96253	Cushing disease		276
HP:0100852	HP:0000739	Anxiety	1	BRD4 CL E G H	23476	13575	ORPHA:199	Cornelia de Lange syndrome	HP:0040282 - Frequent
HP:0100852	HP:0000739	Anxiety	1	BUD23 CL E G H	114049	16405	ORPHA:904	Williams syndrome	HP:0040281 - Very frequent
HP:0100852	HP:0000739	Anxiety	1	C9ORF72 CL E G H	203228	28337	ORPHA:803	Amyotrophic lateral sclerosis	HP:0040282 - Frequent	56
HP:0100852	HP:0000739	Anxiety	1	C9ORF72 CL E G H	203228	28337	ORPHA:401901	Huntington disease-like syndrome due to C9ORF72 expansions	HP:0040283 - Occasional	56
HP:0100852	HP:0000739	Anxiety	1	C9ORF72 CL E G H	203228	28337	ORPHA:100070	Progressive non-fluent aphasia	HP:0040282 - Frequent	56
HP:0100852	HP:0000739	Anxiety	1	CABP4 CL E G H	57010	1386	ORPHA:98784	Autosomal dominant nocturnal frontal lobe epilepsy	HP:0040283 - Occasional	94
HP:0100852	HP:0000739	Anxiety	1	CACNA1A CL E G H	773	1388	OMIM:141500	Migraine, familial hemiplegic, 1	.	449
HP:0100852	HP:0000739	Anxiety	1	CACNA1H CL E G H	8912	1395	ORPHA:64280	Childhood absence epilepsy	HP:0040283 - Occasional	75
HP:0100852	HP:0000739	Anxiety	1	CASR CL E G H	846	1514	ORPHA:428	Autosomal dominant hypocalcemia	HP:0040281 - Very frequent	272
HP:0100852	HP:0000739	Anxiety	1	CCND1 CL E G H	595	1582	ORPHA:892	Von Hippel-Lindau disease	HP:0040283 - Occasional	1
HP:0100852	HP:0000739	Anxiety	1	CCNF CL E G H	899	1591	ORPHA:803	Amyotrophic lateral sclerosis	HP:0040282 - Frequent
HP:0100852	HP:0000739	Anxiety	1	CDC42BPB CL E G H	9578	1738	OMIM:619841
HP:0100852	HP:0000739	Anxiety	1	CDH2 CL E G H	1000	1759	OMIM:618929	AGENESIS OF CORPUS CALLOSUM, CARDIAC, OCULAR, AND GENITAL SYNDROME; ACOGS
HP:0100852	HP:0025269	Panic attack	1	CDH23 CL E G H	64072	13733	ORPHA:96253	Cushing disease		636
HP:0100852	HP:0000739	Anxiety	1	CDH23 CL E G H	64072	13733	ORPHA:231169	Usher syndrome type 1	HP:0040283 - Occasional	636
HP:0100852	HP:0025269	Panic attack	1	CDKL5 CL E G H	6792	11411	ORPHA:3095	Atypical Rett syndrome	HP:0040283 - Occasional	405
HP:0100852	HP:0025269	Panic attack	1	CDKN2A CL E G H	1029	1787	ORPHA:1501	Adrenocortical carcinoma	HP:0040282 - Frequent	289
HP:0100852	HP:0000739	Anxiety	1	CDKN2A CL E G H	1029	1787	ORPHA:1501	Adrenocortical carcinoma	HP:0040282 - Frequent	289
HP:0100852	HP:0000739	Anxiety	1	CDON CL E G H	50937	17104	ORPHA:93925	Alobar holoprosencephaly	HP:0040282 - Frequent	200
HP:0100852	HP:0000739	Anxiety	1	CDON CL E G H	50937	17104	ORPHA:93924	Lobar holoprosencephaly	HP:0040282 - Frequent	200
HP:0100852	HP:0000739	Anxiety	1	CDON CL E G H	50937	17104	ORPHA:93926	Midline interhemispheric variant of holoprosencephaly	HP:0040282 - Frequent	200
HP:0100852	HP:0000739	Anxiety	1	CDON CL E G H	50937	17104	ORPHA:220386	Semilobar holoprosencephaly	HP:0040282 - Frequent	200
HP:0100852	HP:0000739	Anxiety	1	CEACAM3 CL E G H	1084	1815	ORPHA:586	Cystic fibrosis
HP:0100852	HP:0000739	Anxiety	1	CEACAM6 CL E G H	4680	1818	ORPHA:586	Cystic fibrosis		1
HP:0100852	HP:0000739	Anxiety	1	CEP78 CL E G H	84131	25740	ORPHA:231183	Usher syndrome type 3	HP:0040283 - Occasional	9
HP:0100852	HP:0000739	Anxiety	1	CFAP410 CL E G H	755	1260	ORPHA:803	Amyotrophic lateral sclerosis	HP:0040282 - Frequent
HP:0100852	HP:0000739	Anxiety	1	CFTR CL E G H	1080	1884	ORPHA:586	Cystic fibrosis		1371
HP:0100852	HP:0000739	Anxiety	1	CHCHD10 CL E G H	400916	15559	ORPHA:803	Amyotrophic lateral sclerosis	HP:0040282 - Frequent	11
HP:0100852	HP:0000739	Anxiety	1	CHD7 CL E G H	55636	20626	ORPHA:432	Normosmic congenital hypogonadotropic hypogonadism	HP:0040282 - Frequent	515
HP:0100852	HP:0000739	Anxiety	1	CHD8 CL E G H	57680	20153	OMIM:615032	AUTISM, SUSCEPTIBILITY TO, 18; AUTS18		72
HP:0100852	HP:0000739	Anxiety	1	CHMP2B CL E G H	25978	24537	ORPHA:803	Amyotrophic lateral sclerosis	HP:0040282 - Frequent	42
HP:0100852	HP:0000739	Anxiety	1	CHMP2B CL E G H	25978	24537	ORPHA:100070	Progressive non-fluent aphasia	HP:0040282 - Frequent	42
HP:0100852	HP:0000739	Anxiety	1	CHRNA2 CL E G H	1135	1956	ORPHA:98784	Autosomal dominant nocturnal frontal lobe epilepsy	HP:0040283 - Occasional	188
HP:0100852	HP:0000739	Anxiety	1	CHRNA4 CL E G H	1137	1958	ORPHA:98784	Autosomal dominant nocturnal frontal lobe epilepsy	HP:0040283 - Occasional	225
HP:0100852	HP:0000739	Anxiety	1	CHRNB2 CL E G H	1141	1962	ORPHA:98784	Autosomal dominant nocturnal frontal lobe epilepsy	HP:0040283 - Occasional	88
HP:0100852	HP:0000739	Anxiety	1	CIB2 CL E G H	10518	24579	ORPHA:231169	Usher syndrome type 1	HP:0040283 - Occasional	15
HP:0100852	HP:0000739	Anxiety	1	CIC CL E G H	23152	14214	OMIM:617600	Mental retardation, autosomal dominant 45		39
HP:0100852	HP:0025269	Panic attack	1	CIZ1 CL E G H	25792	16744	ORPHA:420492	Adult-onset cervical dystonia, DYT23 type	HP:0040283 - Occasional	16
HP:0100852	HP:0000739	Anxiety	1	CLCA4 CL E G H	22802	2018	ORPHA:586	Cystic fibrosis
HP:0100852	HP:0000739	Anxiety	1	CLCN3 CL E G H	1182	2021	OMIM:619512	NEURODEVELOPMENTAL DISORDER WITH HYPOTONIA AND BRAIN ABNORMALITIES; NEDHYBA		2
HP:0100852	HP:0000739	Anxiety	1	CLCN4 CL E G H	1183	2022	ORPHA:485350	CLCN4-related X-linked intellectual disability syndrome	HP:0040283 - Occasional	45
HP:0100852	HP:0000739	Anxiety	1	CLCN4 CL E G H	1183	2022	OMIM:300114	Raynaud-Claes syndrome	.	45
HP:0100852	HP:0000739	Anxiety	1	CLIP2 CL E G H	7461	2586	ORPHA:904	Williams syndrome	HP:0040281 - Very frequent
HP:0100852	HP:0000739	Anxiety	1	CLN3 CL E G H	1201	2074	OMIM:204200	Ceroid lipofuscinosis, neuronal, 3	.	216
HP:0100852	HP:0000739	Anxiety	1	CLN3 CL E G H	1201	2074	ORPHA:228346	CLN3 disease		216
HP:0100852	HP:0000739	Anxiety	1	CLN5 CL E G H	1203	2076	ORPHA:228360	CLN5 disease	HP:0040283 - Occasional	141
HP:0100852	HP:0000739	Anxiety	1	CLRN1 CL E G H	7401	12605	ORPHA:231183	Usher syndrome type 3	HP:0040283 - Occasional	60
HP:0100852	HP:0000739	Anxiety	1	CLTRN CL E G H	57393	29437	ORPHA:2116	Hartnup disease	HP:0040281 - Very frequent
HP:0100852	HP:0000739	Anxiety	1	COL7A1 CL E G H	1294	2214	ORPHA:89842	Autosomal recessive generalized dystrophic epidermolysis bullosa, intermediate form	HP:0040283 - Occasional	263
HP:0100852	HP:0000739	Anxiety	1	COL7A1 CL E G H	1294	2214	ORPHA:79408	Autosomal recessive generalized dystrophic epidermolysis bullosa, severe form	HP:0040282 - Frequent	263
HP:0100852	HP:0000739	Anxiety	1	COMT CL E G H	1312	2228	ORPHA:567	22q11.2 deletion syndrome	HP:0040283 - Occasional	6
HP:0100852	HP:0000739	Anxiety	1	COMT CL E G H	1312	2228	OMIM:167870	Panic disorder 1	.	6
HP:0100852	HP:0000739	Anxiety	1	COQ2 CL E G H	27235	25223	ORPHA:227510	Multiple system atrophy, cerebellar type	HP:0040282 - Frequent	54
HP:0100852	HP:0000739	Anxiety	1	COQ2 CL E G H	27235	25223	ORPHA:98933	Multiple system atrophy, parkinsonian type	HP:0040282 - Frequent	54
HP:0100852	HP:0000739	Anxiety	1	COX1 CL E G H	4512	7419	ORPHA:550	MELAS	HP:0040282 - Frequent
HP:0100852	HP:0000739	Anxiety	1	COX2 CL E G H	4513	7421	ORPHA:550	MELAS	HP:0040282 - Frequent
HP:0100852	HP:0000739	Anxiety	1	COX3 CL E G H	4514	7422	ORPHA:550	MELAS	HP:0040282 - Frequent
HP:0100852	HP:0000739	Anxiety	1	CPOX CL E G H	1371	2321	OMIM:121300	Coproporphyria	.	72
HP:0100852	HP:0000756	Agoraphobia	1	CREBBP CL E G H	1387	2348	ORPHA:353281	Rubinstein-Taybi syndrome due to 16p13.3 microdeletion	HP:0040282 - Frequent	291
HP:0100852	HP:0025269	Panic attack	1	CREBBP CL E G H	1387	2348	ORPHA:353281	Rubinstein-Taybi syndrome due to 16p13.3 microdeletion	HP:0040282 - Frequent	291
HP:0100852	HP:0000756	Agoraphobia	1	CREBBP CL E G H	1387	2348	ORPHA:353277	Rubinstein-Taybi syndrome due to CREBBP mutations	HP:0040282 - Frequent	291
HP:0100852	HP:0025269	Panic attack	1	CREBBP CL E G H	1387	2348	ORPHA:353277	Rubinstein-Taybi syndrome due to CREBBP mutations	HP:0040282 - Frequent	291
HP:0100852	HP:0000739	Anxiety	1	CRH CL E G H	1392	2355	ORPHA:98784	Autosomal dominant nocturnal frontal lobe epilepsy	HP:0040283 - Occasional	1
HP:0100852	HP:0000739	Anxiety	1	CTNNB1 CL E G H	1499	2514	ORPHA:1501	Adrenocortical carcinoma	HP:0040282 - Frequent	88
HP:0100852	HP:0025269	Panic attack	1	CTNNB1 CL E G H	1499	2514	ORPHA:1501	Adrenocortical carcinoma	HP:0040282 - Frequent	88
HP:0100852	HP:0000739	Anxiety	1	DAO CL E G H	1610	2671	ORPHA:803	Amyotrophic lateral sclerosis	HP:0040282 - Frequent
HP:0100852	HP:0000739	Anxiety	1	DCTN1 CL E G H	1639	2711	ORPHA:803	Amyotrophic lateral sclerosis	HP:0040282 - Frequent	86
HP:0100852	HP:0000739	Anxiety	1	DCTN1 CL E G H	1639	2711	OMIM:168605	Perry syndrome		86
HP:0100852	HP:0000739	Anxiety	1	DCTN4 CL E G H	51164	15518	ORPHA:586	Cystic fibrosis
HP:0100852	HP:0000739	Anxiety	1	DDB1 CL E G H	1642	2717	OMIM:619426	WHITE-KERNOHAN SYNDROME; WHIKERS
HP:0100852	HP:0000739	Anxiety	1	DEAF1 CL E G H	10522	14677	ORPHA:819	Smith-Magenis syndrome	HP:0040281 - Very frequent	33
HP:0100852	HP:0000739	Anxiety	1	DEPDC5 CL E G H	9681	18423	ORPHA:98784	Autosomal dominant nocturnal frontal lobe epilepsy	HP:0040283 - Occasional	172
HP:0100852	HP:0000739	Anxiety	1	DISP1 CL E G H	84976	19711	ORPHA:93925	Alobar holoprosencephaly	HP:0040282 - Frequent	22
HP:0100852	HP:0000739	Anxiety	1	DISP1 CL E G H	84976	19711	ORPHA:93924	Lobar holoprosencephaly	HP:0040282 - Frequent	22
HP:0100852	HP:0000739	Anxiety	1	DISP1 CL E G H	84976	19711	ORPHA:93926	Midline interhemispheric variant of holoprosencephaly	HP:0040282 - Frequent	22
HP:0100852	HP:0000739	Anxiety	1	DISP1 CL E G H	84976	19711	ORPHA:220386	Semilobar holoprosencephaly	HP:0040282 - Frequent	22
HP:0100852	HP:0000739	Anxiety	1	DLAT CL E G H	1737	2896	ORPHA:79244	Pyruvate dehydrogenase E2 deficiency	HP:0040283 - Occasional	82
HP:0100852	HP:0000739	Anxiety	1	DLL1 CL E G H	28514	2908	ORPHA:93925	Alobar holoprosencephaly	HP:0040282 - Frequent	3
HP:0100852	HP:0000739	Anxiety	1	DLL1 CL E G H	28514	2908	ORPHA:93924	Lobar holoprosencephaly	HP:0040282 - Frequent	3
HP:0100852	HP:0000739	Anxiety	1	DLL1 CL E G H	28514	2908	ORPHA:93926	Midline interhemispheric variant of holoprosencephaly	HP:0040282 - Frequent	3
HP:0100852	HP:0000739	Anxiety	1	DLL1 CL E G H	28514	2908	ORPHA:220386	Semilobar holoprosencephaly	HP:0040282 - Frequent	3
HP:0100852	HP:0000739	Anxiety	1	DLST CL E G H	1743	2911	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma
HP:0100852	HP:0025269	Panic attack	1	DLST CL E G H	1743	2911	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma	HP:0040283 - Occasional
HP:0100852	HP:0000739	Anxiety	1	DNAJC30 CL E G H	84277	16410	ORPHA:904	Williams syndrome	HP:0040281 - Very frequent
HP:0100852	HP:0000739	Anxiety	1	DNAJC6 CL E G H	9829	15469	ORPHA:2828	Young-onset Parkinson disease	HP:0040283 - Occasional	6
HP:0100852	HP:0025269	Panic attack	1	DNAJC6 CL E G H	9829	15469	ORPHA:2828	Young-onset Parkinson disease	HP:0040283 - Occasional	6
HP:0100852	HP:0025269	Panic attack	1	DNMT3A CL E G H	1788	2978	ORPHA:276621	Sporadic pheochromocytoma/secreting paraganglioma	HP:0040283 - Occasional	44
HP:0100852	HP:0000739	Anxiety	1	DNMT3A CL E G H	1788	2978	ORPHA:276621	Sporadic pheochromocytoma/secreting paraganglioma		44
HP:0100852	HP:0000739	Anxiety	1	DNMT3A CL E G H	1788	2978	ORPHA:404443	Tatton-Brown-Rahman syndrome	HP:0040283 - Occasional	44
HP:0100852	HP:0000739	Anxiety	1	DPH1 CL E G H	1801	3003	ORPHA:459061	Craniofacial dysplasia-short stature-ectodermal anomalies-intellectual disability syndrome	HP:0040283 - Occasional	3
HP:0100852	HP:0025269	Panic attack	1	DRD2 CL E G H	1813	3023	ORPHA:36899	Myoclonus-dystonia syndrome	HP:0040282 - Frequent	16
HP:0100852	HP:0000739	Anxiety	1	DRD2 CL E G H	1813	3023	ORPHA:36899	Myoclonus-dystonia syndrome	HP:0040282 - Frequent	16
HP:0100852	HP:0000739	Anxiety	1	DUSP6 CL E G H	1848	3072	ORPHA:432	Normosmic congenital hypogonadotropic hypogonadism	HP:0040282 - Frequent	4
HP:0100852	HP:0000739	Anxiety	1	DYRK1A CL E G H	1859	3091	ORPHA:268261	DYRK1A-related intellectual disability syndrome due to 21q22.13q22.2 microdeletion	HP:0040283 - Occasional	134
HP:0100852	HP:0000739	Anxiety	1	DYRK1A CL E G H	1859	3091	ORPHA:464311	Intellectual disability syndrome due to a DYRK1A point mutation	HP:0040282 - Frequent	134
HP:0100852	HP:0000739	Anxiety	1	EDNRA CL E G H	1909	3179	ORPHA:586	Cystic fibrosis		3
HP:0100852	HP:0000739	Anxiety	1	EHMT1 CL E G H	79813	24650	ORPHA:96147	Kleefstra syndrome due to 9q34 microdeletion	HP:0040283 - Occasional	223
HP:0100852	HP:0000739	Anxiety	1	EIF2AK1 CL E G H	27102	24921	OMIM:618878	LEUKOENCEPHALOPATHY, MOTOR DELAY, SPASTICITY, AND DYSARTHRIA SYNDROME; LEMSPAD
HP:0100852	HP:0000739	Anxiety	1	EIF4H CL E G H	7458	12741	ORPHA:904	Williams syndrome	HP:0040281 - Very frequent
HP:0100852	HP:0000739	Anxiety	1	ELN CL E G H	2006	3327	ORPHA:904	Williams syndrome	HP:0040281 - Very frequent	172
HP:0100852	HP:0000739	Anxiety	1	ELN CL E G H	2006	3327	OMIM:194050	Williams-Beuren syndrome		172
HP:0100852	HP:0000739	Anxiety	1	EMC10 CL E G H	284361	27609	OMIM:619264	NEURODEVELOPMENTAL DISORDER WITH DYSMORPHIC FACIES AND VARIABLE SEIZURES; NEDDFAS
HP:0100852	HP:0025269	Panic attack	1	EP300 CL E G H	2033	3373	ORPHA:353284	Rubinstein-Taybi syndrome due to EP300 haploinsufficiency	HP:0040282 - Frequent	250
HP:0100852	HP:0000756	Agoraphobia	1	EP300 CL E G H	2033	3373	ORPHA:353284	Rubinstein-Taybi syndrome due to EP300 haploinsufficiency	HP:0040282 - Frequent	250
HP:0100852	HP:0025269	Panic attack	1	EPAS1 CL E G H	2034	3374	ORPHA:276621	Sporadic pheochromocytoma/secreting paraganglioma	HP:0040283 - Occasional	112
HP:0100852	HP:0000739	Anxiety	1	EPAS1 CL E G H	2034	3374	ORPHA:276621	Sporadic pheochromocytoma/secreting paraganglioma		112
HP:0100852	HP:0000739	Anxiety	1	EPCAM CL E G H	4072	11529	ORPHA:144	Lynch syndrome	HP:0040282 - Frequent	170
HP:0100852	HP:0000739	Anxiety	1	EPHA4 CL E G H	2043	3388	ORPHA:803	Amyotrophic lateral sclerosis	HP:0040282 - Frequent	4
HP:0100852	HP:0000739	Anxiety	1	ERBB4 CL E G H	2066	3432	ORPHA:803	Amyotrophic lateral sclerosis	HP:0040282 - Frequent	15
HP:0100852	HP:0000739	Anxiety	1	ESPN CL E G H	83715	13281	ORPHA:231169	Usher syndrome type 1	HP:0040283 - Occasional	33
HP:0100852	HP:0000739	Anxiety	1	FA2H CL E G H	79152	21197	ORPHA:329308	Fatty acid hydroxylase-associated neurodegeneration	HP:0040284 - Very rare	76
HP:0100852	HP:0000739	Anxiety	1	FAN1 CL E G H	22909	29170	ORPHA:144	Lynch syndrome	HP:0040282 - Frequent	15
HP:0100852	HP:0000739	Anxiety	1	FGF17 CL E G H	8822	3673	ORPHA:432	Normosmic congenital hypogonadotropic hypogonadism	HP:0040282 - Frequent	3
HP:0100852	HP:0000739	Anxiety	1	FGF8 CL E G H	2253	3686	ORPHA:93925	Alobar holoprosencephaly	HP:0040282 - Frequent	17
HP:0100852	HP:0000739	Anxiety	1	FGF8 CL E G H	2253	3686	ORPHA:93924	Lobar holoprosencephaly	HP:0040282 - Frequent	17
HP:0100852	HP:0000739	Anxiety	1	FGF8 CL E G H	2253	3686	ORPHA:93926	Midline interhemispheric variant of holoprosencephaly	HP:0040282 - Frequent	17
HP:0100852	HP:0000739	Anxiety	1	FGF8 CL E G H	2253	3686	ORPHA:432	Normosmic congenital hypogonadotropic hypogonadism	HP:0040282 - Frequent	17
HP:0100852	HP:0000739	Anxiety	1	FGF8 CL E G H	2253	3686	ORPHA:220386	Semilobar holoprosencephaly	HP:0040282 - Frequent	17
HP:0100852	HP:0000739	Anxiety	1	FGFR1 CL E G H	2260	3688	ORPHA:93924	Lobar holoprosencephaly	HP:0040282 - Frequent	172
HP:0100852	HP:0000739	Anxiety	1	FGFR1 CL E G H	2260	3688	ORPHA:432	Normosmic congenital hypogonadotropic hypogonadism	HP:0040282 - Frequent	172
HP:0100852	HP:0000739	Anxiety	1	FGFR1 CL E G H	2260	3688	ORPHA:220386	Semilobar holoprosencephaly	HP:0040282 - Frequent	172
HP:0100852	HP:0025269	Panic attack	1	FH CL E G H	2271	3700	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma	HP:0040283 - Occasional	301
HP:0100852	HP:0000739	Anxiety	1	FH CL E G H	2271	3700	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma		301
HP:0100852	HP:0000739	Anxiety	1	FIG4 CL E G H	9896	16873	ORPHA:803	Amyotrophic lateral sclerosis	HP:0040282 - Frequent	111
HP:0100852	HP:0000739	Anxiety	1	FKBP6 CL E G H	8468	3722	ORPHA:904	Williams syndrome	HP:0040281 - Very frequent
HP:0100852	HP:0000739	Anxiety	1	FLII CL E G H	2314	3750	ORPHA:819	Smith-Magenis syndrome	HP:0040281 - Very frequent
HP:0100852	HP:0000739	Anxiety	1	FLT4 CL E G H	2324	3767	OMIM:618780	CONGENITAL HEART DEFECTS, MULTIPLE TYPES, 7; CHTD7		90
HP:0100852	HP:0000739	Anxiety	1	FMO3 CL E G H	2328	3771	ORPHA:468726	Severe primary trimethylaminuria	HP:0040283 - Occasional	55
HP:0100852	HP:0000739	Anxiety	1	FMR1 CL E G H	2332	3775	ORPHA:908	Fragile X syndrome	HP:0040283 - Occasional	30
HP:0100852	HP:0000739	Anxiety	1	FMR1 CL E G H	2332	3775	OMIM:300623	Fragile X tremor/ataxia syndrome		30
HP:0100852	HP:0000739	Anxiety	1	FMR1 CL E G H	2332	3775	ORPHA:93256	Fragile X-associated tremor/ataxia syndrome	HP:0040282 - Frequent	30
HP:0100852	HP:0000739	Anxiety	1	FMR1 CL E G H	2332	3775	ORPHA:449291	Symptomatic form of fragile X syndrome in female carriers	HP:0040282 - Frequent	30
HP:0100852	HP:0000739	Anxiety	1	FOXH1 CL E G H	8928	3814	ORPHA:93925	Alobar holoprosencephaly	HP:0040282 - Frequent	48
HP:0100852	HP:0000739	Anxiety	1	FOXH1 CL E G H	8928	3814	ORPHA:93924	Lobar holoprosencephaly	HP:0040282 - Frequent	48
HP:0100852	HP:0000739	Anxiety	1	FOXH1 CL E G H	8928	3814	ORPHA:93926	Midline interhemispheric variant of holoprosencephaly	HP:0040282 - Frequent	48
HP:0100852	HP:0000739	Anxiety	1	FOXH1 CL E G H	8928	3814	ORPHA:220386	Semilobar holoprosencephaly	HP:0040282 - Frequent	48
HP:0100852	HP:0000739	Anxiety	1	FOXP1 CL E G H	27086	3823	ORPHA:391372	Intellectual disability-severe speech delay-mild dysmorphism syndrome	HP:0040282 - Frequent	184
HP:0100852	HP:0000739	Anxiety	1	FOXP1 CL E G H	27086	3823	OMIM:613670	Mental retardation with language impairment and with or without autistic features		184
HP:0100852	HP:0000739	Anxiety	1	FRMD5 CL E G H	84978	28214	OMIM:620094
HP:0100852	HP:0000739	Anxiety	1	FTSJ1 CL E G H	24140	13254	OMIM:309549	Mental retardation, X-linked 9		13
HP:0100852	HP:0000739	Anxiety	1	FUS CL E G H	2521	4010	ORPHA:803	Amyotrophic lateral sclerosis	HP:0040282 - Frequent	105
HP:0100852	HP:0000739	Anxiety	1	FUZ CL E G H	80199	26219	ORPHA:1136	Arnold-Chiari malformation type II	HP:0040283 - Occasional	3
HP:0100852	HP:0025269	Panic attack	1	GABBR2 CL E G H	9568	4507	ORPHA:3095	Atypical Rett syndrome	HP:0040283 - Occasional	5
HP:0100852	HP:0000739	Anxiety	1	GABRA1 CL E G H	2554	4075	ORPHA:64280	Childhood absence epilepsy	HP:0040283 - Occasional	134
HP:0100852	HP:0000739	Anxiety	1	GABRA1 CL E G H	2554	4075	ORPHA:33069	Dravet syndrome	HP:0040282 - Frequent	134
HP:0100852	HP:0000739	Anxiety	1	GABRB3 CL E G H	2562	4083	ORPHA:64280	Childhood absence epilepsy	HP:0040283 - Occasional	57
HP:0100852	HP:0000739	Anxiety	1	GABRD CL E G H	2563	4084	ORPHA:36387	Generalized epilepsy with febrile seizures-plus	HP:0040284 - Very rare	10
HP:0100852	HP:0000739	Anxiety	1	GABRG2 CL E G H	2566	4087	ORPHA:64280	Childhood absence epilepsy	HP:0040283 - Occasional	139
HP:0100852	HP:0000739	Anxiety	1	GABRG2 CL E G H	2566	4087	ORPHA:33069	Dravet syndrome	HP:0040282 - Frequent	139
HP:0100852	HP:0000739	Anxiety	1	GABRG2 CL E G H	2566	4087	ORPHA:36387	Generalized epilepsy with febrile seizures-plus	HP:0040284 - Very rare	139
HP:0100852	HP:0000739	Anxiety	1	GABRG2 CL E G H	2566	4087	ORPHA:1945	Rolandic epilepsy	HP:0040283 - Occasional	139
HP:0100852	HP:0000739	Anxiety	1	GALT CL E G H	2592	4135	ORPHA:79239	Classic galactosemia	HP:0040283 - Occasional	351
HP:0100852	HP:0000739	Anxiety	1	GAS1 CL E G H	2619	4165	ORPHA:93925	Alobar holoprosencephaly	HP:0040282 - Frequent	2
HP:0100852	HP:0000739	Anxiety	1	GAS1 CL E G H	2619	4165	ORPHA:93924	Lobar holoprosencephaly	HP:0040282 - Frequent	2
HP:0100852	HP:0000739	Anxiety	1	GAS1 CL E G H	2619	4165	ORPHA:93926	Midline interhemispheric variant of holoprosencephaly	HP:0040282 - Frequent	2
HP:0100852	HP:0000739	Anxiety	1	GAS1 CL E G H	2619	4165	ORPHA:220386	Semilobar holoprosencephaly	HP:0040282 - Frequent	2
HP:0100852	HP:0000739	Anxiety	1	GCH1 CL E G H	2643	4193	ORPHA:98808	Autosomal dominant dopa-responsive dystonia	HP:0040282 - Frequent	86
HP:0100852	HP:0000739	Anxiety	1	GCLC CL E G H	2729	4311	ORPHA:586	Cystic fibrosis		2
HP:0100852	HP:0000739	Anxiety	1	GLA CL E G H	2717	4296	ORPHA:324	Fabry disease	HP:0040283 - Occasional	291
HP:0100852	HP:0000739	Anxiety	1	GLE1 CL E G H	2733	4315	ORPHA:803	Amyotrophic lateral sclerosis	HP:0040282 - Frequent	45
HP:0100852	HP:0000739	Anxiety	1	GLI2 CL E G H	2736	4318	ORPHA:93925	Alobar holoprosencephaly	HP:0040282 - Frequent	173
HP:0100852	HP:0000739	Anxiety	1	GLI2 CL E G H	2736	4318	ORPHA:93924	Lobar holoprosencephaly	HP:0040282 - Frequent	173
HP:0100852	HP:0000739	Anxiety	1	GLI2 CL E G H	2736	4318	ORPHA:93926	Midline interhemispheric variant of holoprosencephaly	HP:0040282 - Frequent	173
HP:0100852	HP:0000739	Anxiety	1	GLI2 CL E G H	2736	4318	ORPHA:220386	Semilobar holoprosencephaly	HP:0040282 - Frequent	173
HP:0100852	HP:0000739	Anxiety	1	GLT8D1 CL E G H	55830	24870	ORPHA:803	Amyotrophic lateral sclerosis	HP:0040282 - Frequent
HP:0100852	HP:0000739	Anxiety	1	GM2A CL E G H	2760	4367	ORPHA:309246	GM2 gangliosidosis, AB variant	HP:0040282 - Frequent	69
HP:0100852	HP:0000739	Anxiety	1	GNA11 CL E G H	2767	4379	ORPHA:428	Autosomal dominant hypocalcemia	HP:0040281 - Very frequent	16
HP:0100852	HP:0000739	Anxiety	1	GNAS CL E G H	2778	4392	OMIM:219080	ACTH-independent macronodular adrenal hyperplasia	.	101
HP:0100852	HP:0000739	Anxiety	1	GNAS CL E G H	2778	4392	ORPHA:79443	Pseudohypoparathyroidism type 1A	HP:0040283 - Occasional	101
HP:0100852	HP:0000739	Anxiety	1	GNAS CL E G H	2778	4392	ORPHA:94089	Pseudohypoparathyroidism type 1B	HP:0040283 - Occasional	101
HP:0100852	HP:0000739	Anxiety	1	GNAS CL E G H	2778	4392	ORPHA:79444	Pseudohypoparathyroidism type 1C	HP:0040283 - Occasional	101
HP:0100852	HP:0000739	Anxiety	1	GNB1 CL E G H	2782	4396	OMIM:616973	Mental retardation, autosomal dominant 42		12
HP:0100852	HP:0000739	Anxiety	1	GNRH1 CL E G H	2796	4419	ORPHA:432	Normosmic congenital hypogonadotropic hypogonadism	HP:0040282 - Frequent	15
HP:0100852	HP:0000739	Anxiety	1	GNRHR CL E G H	2798	4421	ORPHA:432	Normosmic congenital hypogonadotropic hypogonadism	HP:0040282 - Frequent	92
HP:0100852	HP:0000739	Anxiety	1	GP1BB CL E G H	2812	4440	ORPHA:567	22q11.2 deletion syndrome	HP:0040283 - Occasional	8
HP:0100852	HP:0000739	Anxiety	1	GPR101 CL E G H	83550	14963	ORPHA:963	Acromegaly	HP:0040282 - Frequent	5
HP:0100852	HP:0000739	Anxiety	1	GRIK2 CL E G H	2898	4580	OMIM:619580	NEURODEVELOPMENTAL DISORDER WITH IMPAIRED LANGUAGE AND ATAXIA AND WITH OR WITHOUT SEIZURES; NEDLAS		32
HP:0100852	HP:0000739	Anxiety	1	GRIN2A CL E G H	2903	4585	ORPHA:98818	Landau-Kleffner syndrome	HP:0040283 - Occasional	434
HP:0100852	HP:0000739	Anxiety	1	GRIN2A CL E G H	2903	4585	ORPHA:1945	Rolandic epilepsy	HP:0040283 - Occasional	434
HP:0100852	HP:0000739	Anxiety	1	GRN CL E G H	2896	4601	ORPHA:100070	Progressive non-fluent aphasia	HP:0040282 - Frequent	126
HP:0100852	HP:0000739	Anxiety	1	GSTM3 CL E G H	2947	4635	ORPHA:586	Cystic fibrosis		1
HP:0100852	HP:0000739	Anxiety	1	GTF2I CL E G H	2969	4659	ORPHA:904	Williams syndrome	HP:0040281 - Very frequent	1
HP:0100852	HP:0000739	Anxiety	1	GTF2IRD1 CL E G H	9569	4661	ORPHA:904	Williams syndrome	HP:0040281 - Very frequent	1
HP:0100852	HP:0000739	Anxiety	1	GTF2IRD2 CL E G H	84163	30775	ORPHA:904	Williams syndrome	HP:0040281 - Very frequent	1
HP:0100852	HP:0000739	Anxiety	1	H1-4 CL E G H	3008	4718	OMIM:617537	Rahman syndrome
HP:0100852	HP:0000739	Anxiety	1	HARS1 CL E G H	3035	4816	ORPHA:231183	Usher syndrome type 3	HP:0040283 - Occasional
HP:0100852	HP:0000739	Anxiety	1	HCN1 CL E G H	348980	4845	ORPHA:36387	Generalized epilepsy with febrile seizures-plus	HP:0040284 - Very rare	54
HP:0100852	HP:0000739	Anxiety	1	HDAC8 CL E G H	55869	13315	ORPHA:199	Cornelia de Lange syndrome	HP:0040282 - Frequent	37
HP:0100852	HP:0000739	Anxiety	1	HEXB CL E G H	3074	4879	ORPHA:309169	Sandhoff disease, adult form		80
HP:0100852	HP:0000739	Anxiety	1	HFE CL E G H	3077	4886	ORPHA:586	Cystic fibrosis		38
HP:0100852	HP:0000739	Anxiety	1	HIRA CL E G H	7290	4916	ORPHA:567	22q11.2 deletion syndrome	HP:0040283 - Occasional	3
HP:0100852	HP:0000739	Anxiety	1	HIVEP2 CL E G H	3097	4921	OMIM:616977	Mental retardation, autosomal dominant 43	.	13
HP:0100852	HP:0000739	Anxiety	1	HLA-DQA1 CL E G H	3117	4942	OMIM:212750	Celiac disease, susceptibility to, 1	.
HP:0100852	HP:0000739	Anxiety	1	HLA-DQB1 CL E G H	3119	4944	OMIM:212750	Celiac disease, susceptibility to, 1	.
HP:0100852	HP:0000739	Anxiety	1	HLA-DQB1 CL E G H	3119	4944	OMIM:123400	Creutzfeldt-Jakob disease	.
HP:0100852	HP:0000739	Anxiety	1	HMBS CL E G H	3145	4982	ORPHA:79276	Acute intermittent porphyria	HP:0040283 - Occasional	81
HP:0100852	HP:0000739	Anxiety	1	HMBS CL E G H	3145	4982	OMIM:176000	Porphyria, acute intermittent	.	81
HP:0100852	HP:0000739	Anxiety	1	HMOX1 CL E G H	3162	5013	ORPHA:586	Cystic fibrosis		3
HP:0100852	HP:0000739	Anxiety	1	HNRNPA1 CL E G H	3178	5031	ORPHA:803	Amyotrophic lateral sclerosis	HP:0040282 - Frequent	31
HP:0100852	HP:0000739	Anxiety	1	HNRNPH2 CL E G H	3188	5042	OMIM:300986	MENTAL RETARDATION, X-LINKED, SYNDROMIC, BAIN TYPE; MRXSB		3
HP:0100852	HP:0000739	Anxiety	1	HS6ST1 CL E G H	9394	5201	ORPHA:432	Normosmic congenital hypogonadotropic hypogonadism	HP:0040282 - Frequent	8
HP:0100852	HP:0000739	Anxiety	1	HSPG2 CL E G H	3339	5273	ORPHA:800	Schwartz-Jampel syndrome	HP:0040283 - Occasional	345
HP:0100852	HP:0000739	Anxiety	1	HTR2A CL E G H	3356	5293	OMIM:164230	Obsessive-Compulsive disorder 1		4
HP:0100852	HP:0000739	Anxiety	1	HTRA1 CL E G H	5654	9476	OMIM:600142	Autosomal recessive cerebral arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL)		34
HP:0100852	HP:0025269	Panic attack	1	HTRA2 CL E G H	27429	14348	ORPHA:2828	Young-onset Parkinson disease	HP:0040283 - Occasional	39
HP:0100852	HP:0000739	Anxiety	1	HTRA2 CL E G H	27429	14348	ORPHA:2828	Young-onset Parkinson disease	HP:0040283 - Occasional	39
HP:0100852	HP:0000739	Anxiety	1	HTT CL E G H	3064	4851	ORPHA:399	Huntington disease	HP:0040282 - Frequent	12
HP:0100852	HP:0000739	Anxiety	1	IFNG CL E G H	3458	5438	ORPHA:805	Tuberous sclerosis complex	HP:0040283 - Occasional	23
HP:0100852	HP:0000739	Anxiety	1	IGF1R CL E G H	3480	5465	OMIM:270450	Insulin-Like growth factor I, resistance to	.	268
HP:0100852	HP:0000739	Anxiety	1	IMPDH2 CL E G H	3615	6053	ORPHA:98808	Autosomal dominant dopa-responsive dystonia	HP:0040282 - Frequent	1
HP:0100852	HP:0000739	Anxiety	1	IQSEC2 CL E G H	23096	29059	ORPHA:819	Smith-Magenis syndrome	HP:0040281 - Very frequent	119
HP:0100852	HP:0000739	Anxiety	1	JMJD1C CL E G H	221037	12313	ORPHA:567	22q11.2 deletion syndrome	HP:0040283 - Occasional	2
HP:0100852	HP:0000739	Anxiety	1	JPH3 CL E G H	57338	14203	OMIM:606438	Huntington disease-like 2	.	2
HP:0100852	HP:0000739	Anxiety	1	JRK CL E G H	8629	6199	ORPHA:64280	Childhood absence epilepsy	HP:0040283 - Occasional
HP:0100852	HP:0000739	Anxiety	1	KANSL1 CL E G H	284058	24565	ORPHA:363958	17q21.31 microdeletion syndrome	HP:0040283 - Occasional	283
HP:0100852	HP:0000739	Anxiety	1	KANSL1 CL E G H	284058	24565	OMIM:610443	Koolen-De Vries syndrome		283
HP:0100852	HP:0000739	Anxiety	1	KANSL1 CL E G H	284058	24565	ORPHA:363965	Koolen-De Vries syndrome due to a point mutation	HP:0040283 - Occasional	283
HP:0100852	HP:0025269	Panic attack	1	KCNN2 CL E G H	3781	6291	OMIM:619725	NEURODEVELOPMENTAL DISORDER WITH OR WITHOUT VARIABLE MOVEMENT OR BEHAVIORAL ABNORMALITIES; NEDMAB
HP:0100852	HP:0000739	Anxiety	1	KCNN2 CL E G H	3781	6291	OMIM:619725	NEURODEVELOPMENTAL DISORDER WITH OR WITHOUT VARIABLE MOVEMENT OR BEHAVIORAL ABNORMALITIES; NEDMAB
HP:0100852	HP:0000739	Anxiety	1	KCNN4 CL E G H	3783	6293	ORPHA:586	Cystic fibrosis		3
HP:0100852	HP:0000739	Anxiety	1	KCNT1 CL E G H	57582	18865	ORPHA:98784	Autosomal dominant nocturnal frontal lobe epilepsy	HP:0040283 - Occasional	321
HP:0100852	HP:0000739	Anxiety	1	KCTD17 CL E G H	79734	25705	OMIM:616398	Dystonia 26, myoclonic	HP:0040283 - Occasional	1
HP:0100852	HP:0025269	Panic attack	1	KCTD17 CL E G H	79734	25705	ORPHA:36899	Myoclonus-dystonia syndrome	HP:0040282 - Frequent	1
HP:0100852	HP:0000739	Anxiety	1	KCTD17 CL E G H	79734	25705	ORPHA:36899	Myoclonus-dystonia syndrome	HP:0040282 - Frequent	1
HP:0100852	HP:0000739	Anxiety	1	KIF1B CL E G H	23095	16636	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma		202
HP:0100852	HP:0025269	Panic attack	1	KIF1B CL E G H	23095	16636	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma	HP:0040283 - Occasional	202
HP:0100852	HP:0000739	Anxiety	1	KISS1 CL E G H	3814	6341	ORPHA:432	Normosmic congenital hypogonadotropic hypogonadism	HP:0040282 - Frequent	3
HP:0100852	HP:0000739	Anxiety	1	KISS1R CL E G H	84634	4510	ORPHA:432	Normosmic congenital hypogonadotropic hypogonadism	HP:0040282 - Frequent	14
HP:0100852	HP:0000739	Anxiety	1	KMT2A CL E G H	4297	7132	ORPHA:319182	Wiedemann-Steiner syndrome	HP:0040282 - Frequent	91
HP:0100852	HP:0000739	Anxiety	1	KMT2B CL E G H	9757	15840	ORPHA:589618	Dystonia 28		11
HP:0100852	HP:0000739	Anxiety	1	KMT2E CL E G H	55904	18541	OMIM:618512	O'donnell-Luria-Rodan syndrome	.	1
HP:0100852	HP:0000739	Anxiety	1	KPTN CL E G H	11133	6404	ORPHA:397612	Macrocephaly-developmental delay syndrome	HP:0040282 - Frequent	13
HP:0100852	HP:0000739	Anxiety	1	KPTN CL E G H	11133	6404	OMIM:615637	Mental retardation, autosomal recessive 41	.	13
HP:0100852	HP:0000739	Anxiety	1	KRAS CL E G H	3845	6407	ORPHA:144	Lynch syndrome	HP:0040282 - Frequent	196
HP:0100852	HP:0000739	Anxiety	1	LARP7 CL E G H	51574	24912	OMIM:615071	Alazami syndrome	.	16
HP:0100852	HP:0000739	Anxiety	1	LARP7 CL E G H	51574	24912	ORPHA:319671	Alazami syndrome	HP:0040282 - Frequent	16
HP:0100852	HP:0000739	Anxiety	1	LGI3 CL E G H	203190	18711	OMIM:620007
HP:0100852	HP:0000739	Anxiety	1	LIMK1 CL E G H	3984	6613	ORPHA:904	Williams syndrome	HP:0040281 - Very frequent
HP:0100852	HP:0000739	Anxiety	1	LRRK2 CL E G H	120892	18618	ORPHA:2828	Young-onset Parkinson disease	HP:0040283 - Occasional	221
HP:0100852	HP:0025269	Panic attack	1	LRRK2 CL E G H	120892	18618	ORPHA:2828	Young-onset Parkinson disease	HP:0040283 - Occasional	221
HP:0100852	HP:0000739	Anxiety	1	MAMLD1 CL E G H	10046	2568	ORPHA:95706	Non-syndromic posterior hypospadias	HP:0040283 - Occasional	5
HP:0100852	HP:0000739	Anxiety	1	MAN2B1 CL E G H	4125	6826	ORPHA:309288	Alpha-mannosidosis, adult form	HP:0040283 - Occasional	136
HP:0100852	HP:0000739	Anxiety	1	MAN2B1 CL E G H	4125	6826	ORPHA:309282	Alpha-mannosidosis, infantile form	HP:0040283 - Occasional	136
HP:0100852	HP:0000739	Anxiety	1	MAPK1 CL E G H	5594	6871	OMIM:619087	NOONAN SYNDROME 13; NS13		2
HP:0100852	HP:0000739	Anxiety	1	MAPT CL E G H	4137	6893	ORPHA:100070	Progressive non-fluent aphasia	HP:0040282 - Frequent	140
HP:0100852	HP:0000739	Anxiety	1	MATR3 CL E G H	9782	6912	ORPHA:803	Amyotrophic lateral sclerosis	HP:0040282 - Frequent	80
HP:0100852	HP:0025269	Panic attack	1	MAX CL E G H	4149	6913	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma	HP:0040283 - Occasional	84
HP:0100852	HP:0000739	Anxiety	1	MAX CL E G H	4149	6913	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma		84
HP:0100852	HP:0000739	Anxiety	1	MBD5 CL E G H	55777	20444	OMIM:156200	Mental retardation, autosomal dominant 1		252
HP:0100852	HP:0000739	Anxiety	1	MDH2 CL E G H	4191	6971	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma		4
HP:0100852	HP:0025269	Panic attack	1	MDH2 CL E G H	4191	6971	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma	HP:0040283 - Occasional	4
HP:0100852	HP:0025269	Panic attack	1	MECP2 CL E G H	4204	6990	ORPHA:3095	Atypical Rett syndrome	HP:0040283 - Occasional	950
HP:0100852	HP:0000739	Anxiety	1	MECP2 CL E G H	4204	6990	OMIM:300260	Mental retardation, x-linked syndromic, Lubs type		950
HP:0100852	HP:0000739	Anxiety	1	MED12L CL E G H	116931	16050	OMIM:618872	NIZON-ISIDOR SYNDROME; NIZIDS
HP:0100852	HP:0000739	Anxiety	1	MEN1 CL E G H	4221	7010	ORPHA:97279	Insulinoma	HP:0040283 - Occasional	462
HP:0100852	HP:0000739	Anxiety	1	METTL27 CL E G H	155368	19068	ORPHA:904	Williams syndrome	HP:0040281 - Very frequent	1
HP:0100852	HP:0000739	Anxiety	1	MIF CL E G H	4282	7097	ORPHA:586	Cystic fibrosis		1
HP:0100852	HP:0000739	Anxiety	1	MIR17HG CL E G H	407975	23564	ORPHA:391646	Feingold syndrome type 2	HP:0040283 - Occasional	1
HP:0100852	HP:0000739	Anxiety	1	MLH1 CL E G H	4292	7127	ORPHA:144	Lynch syndrome	HP:0040282 - Frequent	1819
HP:0100852	HP:0000739	Anxiety	1	MLH3 CL E G H	27030	7128	ORPHA:144	Lynch syndrome	HP:0040282 - Frequent	131
HP:0100852	HP:0000739	Anxiety	1	MLXIPL CL E G H	51085	12744	ORPHA:904	Williams syndrome	HP:0040281 - Very frequent	1
HP:0100852	HP:0000739	Anxiety	1	MLXIPL CL E G H	51085	12744	OMIM:194050	Williams-Beuren syndrome		1
HP:0100852	HP:0000739	Anxiety	1	MMP1 CL E G H	4312	7155	ORPHA:79408	Autosomal recessive generalized dystrophic epidermolysis bullosa, severe form	HP:0040282 - Frequent	6
HP:0100852	HP:0000739	Anxiety	1	MSH2 CL E G H	4436	7325	ORPHA:144	Lynch syndrome	HP:0040282 - Frequent	2162
HP:0100852	HP:0000739	Anxiety	1	MSH6 CL E G H	2956	7329	ORPHA:144	Lynch syndrome	HP:0040282 - Frequent	2232
HP:0100852	HP:0000739	Anxiety	1	MSTO1 CL E G H	55154	29678	ORPHA:502423	Mitochondrial myopathy-cerebellar ataxia-pigmentary retinopathy syndrome	HP:0040282 - Frequent
HP:0100852	HP:0000739	Anxiety	1	MSTO1 CL E G H	55154	29678	OMIM:617675	Myopathy, mitochondrial, and ataxia	.
HP:0100852	HP:0000739	Anxiety	1	MYO7A CL E G H	4647	7606	ORPHA:231169	Usher syndrome type 1	HP:0040283 - Occasional	516
HP:0100852	HP:0000739	Anxiety	1	MYO7A CL E G H	4647	7606	ORPHA:231178	Usher syndrome type 2	HP:0040283 - Occasional	516
HP:0100852	HP:0000739	Anxiety	1	NAGS CL E G H	162417	17996	ORPHA:927	Hyperammonemia due to N-acetylglutamate synthase deficiency	HP:0040283 - Occasional	36
HP:0100852	HP:0000739	Anxiety	1	NCF1 CL E G H	653361	7660	ORPHA:904	Williams syndrome	HP:0040281 - Very frequent	13
HP:0100852	HP:0000739	Anxiety	1	ND1 CL E G H	4535	7455	ORPHA:550	MELAS	HP:0040282 - Frequent
HP:0100852	HP:0000739	Anxiety	1	ND4 CL E G H	4538	7459	ORPHA:550	MELAS	HP:0040282 - Frequent
HP:0100852	HP:0000739	Anxiety	1	ND5 CL E G H	4540	7461	ORPHA:550	MELAS	HP:0040282 - Frequent
HP:0100852	HP:0000739	Anxiety	1	ND6 CL E G H	4541	7462	ORPHA:550	MELAS	HP:0040282 - Frequent
HP:0100852	HP:0000739	Anxiety	1	NDP CL E G H	4693	7678	ORPHA:649	Norrie disease	HP:0040282 - Frequent	39
HP:0100852	HP:0000739	Anxiety	1	NEFH CL E G H	4744	7737	ORPHA:803	Amyotrophic lateral sclerosis	HP:0040282 - Frequent	24
HP:0100852	HP:0000739	Anxiety	1	NEK1 CL E G H	4750	7744	ORPHA:803	Amyotrophic lateral sclerosis	HP:0040282 - Frequent	101
HP:0100852	HP:0000739	Anxiety	1	NEXMIF CL E G H	340533	29433	OMIM:300912	Mental retardation, X-linked 98		52
HP:0100852	HP:0000739	Anxiety	1	NF1 CL E G H	4763	7765	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma		1952
HP:0100852	HP:0025269	Panic attack	1	NF1 CL E G H	4763	7765	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma	HP:0040283 - Occasional	1952
HP:0100852	HP:0000739	Anxiety	1	NFASC CL E G H	23114	29866	OMIM:618356	Neurodevelopmental disorder with central and peripheral motor dysfunction	.
HP:0100852	HP:0000739	Anxiety	1	NFIB CL E G H	4781	7785	OMIM:618286	Macrocephaly, acquired, with impaired intellectual development	HP:0040284 - Very rare	1
HP:0100852	HP:0000739	Anxiety	1	NFIX CL E G H	4784	7788	ORPHA:420179	Malan overgrowth syndrome	HP:0040283 - Occasional	40
HP:0100852	HP:0000739	Anxiety	1	NFIX CL E G H	4784	7788	OMIM:614753	Sotos syndrome 2	.	40
HP:0100852	HP:0000739	Anxiety	1	NIPBL CL E G H	25836	28862	ORPHA:199	Cornelia de Lange syndrome	HP:0040282 - Frequent	494
HP:0100852	HP:0000739	Anxiety	1	NKX2-1 CL E G H	7080	11825	OMIM:118700	Chorea, benign hereditary	.	51
HP:0100852	HP:0000739	Anxiety	1	NODAL CL E G H	4838	7865	ORPHA:93925	Alobar holoprosencephaly	HP:0040282 - Frequent	45
HP:0100852	HP:0000739	Anxiety	1	NODAL CL E G H	4838	7865	ORPHA:93924	Lobar holoprosencephaly	HP:0040282 - Frequent	45
HP:0100852	HP:0000739	Anxiety	1	NODAL CL E G H	4838	7865	ORPHA:93926	Midline interhemispheric variant of holoprosencephaly	HP:0040282 - Frequent	45
HP:0100852	HP:0000739	Anxiety	1	NODAL CL E G H	4838	7865	ORPHA:220386	Semilobar holoprosencephaly	HP:0040282 - Frequent	45
HP:0100852	HP:0000739	Anxiety	1	NONO CL E G H	4841	7871	ORPHA:466791	Macrocephaly-intellectual disability-left ventricular non compaction syndrome	HP:0040282 - Frequent	10
HP:0100852	HP:0000739	Anxiety	1	NOTCH3 CL E G H	4854	7883	ORPHA:136	Cerebral autosomal dominant arteriopathy-subcortical infarcts-leukoencephalopathy	HP:0040283 - Occasional	144
HP:0100852	HP:0025269	Panic attack	1	NR3C1 CL E G H	2908	7978	ORPHA:96253	Cushing disease		79
HP:0100852	HP:0000739	Anxiety	1	NR3C1 CL E G H	2908	7978	OMIM:615962	Glucocorticoid resistance, generalized	HP:0040283 - Occasional	79
HP:0100852	HP:0000739	Anxiety	1	NR4A2 CL E G H	4929	7981	ORPHA:98808	Autosomal dominant dopa-responsive dystonia	HP:0040282 - Frequent	27
HP:0100852	HP:0000739	Anxiety	1	NSD1 CL E G H	64324	14234	ORPHA:821	Sotos syndrome	HP:0040283 - Occasional	544
HP:0100852	HP:0000739	Anxiety	1	NSD2 CL E G H	7468	12766	OMIM:619695	RAUCH-STEINDL SYNDROME; RAUST		118
HP:0100852	HP:0000739	Anxiety	1	NSMF CL E G H	26012	29843	ORPHA:432	Normosmic congenital hypogonadotropic hypogonadism	HP:0040282 - Frequent	6
HP:0100852	HP:0025269	Panic attack	1	NTNG1 CL E G H	22854	23319	ORPHA:3095	Atypical Rett syndrome	HP:0040283 - Occasional	1
HP:0100852	HP:0000739	Anxiety	1	OCRL CL E G H	4952	8108	ORPHA:534	Oculocerebrorenal syndrome of Lowe	HP:0040281 - Very frequent	88
HP:0100852	HP:0000739	Anxiety	1	OPTN CL E G H	10133	17142	ORPHA:803	Amyotrophic lateral sclerosis	HP:0040282 - Frequent	62
HP:0100852	HP:0000739	Anxiety	1	PAK3 CL E G H	5063	8592	OMIM:300558	MENTAL RETARDATION, X-LINKED 30; MRX30		27
HP:0100852	HP:0000739	Anxiety	1	PARK7 CL E G H	11315	16369	OMIM:606324	PARKINSON DISEASE 7, AUTOSOMAL RECESSIVE EARLY-ONSET; PARK7		23
HP:0100852	HP:0025269	Panic attack	1	PARK7 CL E G H	11315	16369	ORPHA:2828	Young-onset Parkinson disease	HP:0040283 - Occasional	23
HP:0100852	HP:0000739	Anxiety	1	PARK7 CL E G H	11315	16369	ORPHA:2828	Young-onset Parkinson disease	HP:0040283 - Occasional	23
HP:0100852	HP:0000739	Anxiety	1	PCDH15 CL E G H	65217	14674	ORPHA:231169	Usher syndrome type 1	HP:0040283 - Occasional	352
HP:0100852	HP:0000739	Anxiety	1	PCDH19 CL E G H	57526	14270	ORPHA:33069	Dravet syndrome	HP:0040282 - Frequent	225
HP:0100852	HP:0000739	Anxiety	1	PCDH19 CL E G H	57526	14270	ORPHA:101039	Female restricted epilepsy with intellectual disability	HP:0040282 - Frequent	225
HP:0100852	HP:0000739	Anxiety	1	PDE10A CL E G H	10846	8772	ORPHA:494541	Childhood-onset benign chorea with striatal involvement	HP:0040283 - Occasional	5
HP:0100852	HP:0000739	Anxiety	1	PDE11A CL E G H	50940	8773	OMIM:610475	Pigmented nodular adrenocortical disease, primary, 2	.	13
HP:0100852	HP:0000739	Anxiety	1	PDGFB CL E G H	5155	8800	OMIM:615483	Basal ganglia calcification, idiopathic, 5	.	9
HP:0100852	HP:0000739	Anxiety	1	PDGFRB CL E G H	5159	8804	OMIM:616592	Kosaki overgrowth syndrome	HP:0040283 - Occasional	28
HP:0100852	HP:0000739	Anxiety	1	PDZD7 CL E G H	79955	26257	ORPHA:231178	Usher syndrome type 2	HP:0040283 - Occasional	40
HP:0100852	HP:0000739	Anxiety	1	PFN1 CL E G H	5216	8881	ORPHA:803	Amyotrophic lateral sclerosis	HP:0040282 - Frequent	6
HP:0100852	HP:0000739	Anxiety	1	PHF21A CL E G H	51317	24156	OMIM:618725	INTELLECTUAL DEVELOPMENTAL DISORDER WITH BEHAVIORAL ABNORMALITIES AND CRANIOFACIAL DYSMORPHISM WITH OR WITHOUT SEIZURES; IDDBCS		2
HP:0100852	HP:0000739	Anxiety	1	PHIP CL E G H	55023	15673	OMIM:617991	Developmental delay, intellectual disability, obesity, and dysmorphic features	.	11
HP:0100852	HP:0000739	Anxiety	1	PIK3CA CL E G H	5290	8975	ORPHA:144	Lynch syndrome	HP:0040282 - Frequent	162
HP:0100852	HP:0000739	Anxiety	1	PINK1 CL E G H	65018	14581	OMIM:605909	Parkinson disease 6, autosomal recessive early-onset	.	55
HP:0100852	HP:0000739	Anxiety	1	PINK1 CL E G H	65018	14581	ORPHA:2828	Young-onset Parkinson disease	HP:0040283 - Occasional	55
HP:0100852	HP:0025269	Panic attack	1	PINK1 CL E G H	65018	14581	ORPHA:2828	Young-onset Parkinson disease	HP:0040283 - Occasional	55
HP:0100852	HP:0000739	Anxiety	1	PLCH1 CL E G H	23007	29185	ORPHA:93925	Alobar holoprosencephaly	HP:0040282 - Frequent
HP:0100852	HP:0000739	Anxiety	1	PMS1 CL E G H	5378	9121	ORPHA:144	Lynch syndrome	HP:0040282 - Frequent	56
HP:0100852	HP:0000739	Anxiety	1	PMS2 CL E G H	5395	9122	ORPHA:144	Lynch syndrome	HP:0040282 - Frequent	1121
HP:0100852	HP:0025269	Panic attack	1	PODXL CL E G H	5420	9171	ORPHA:2828	Young-onset Parkinson disease	HP:0040283 - Occasional	6
HP:0100852	HP:0000739	Anxiety	1	PODXL CL E G H	5420	9171	ORPHA:2828	Young-onset Parkinson disease	HP:0040283 - Occasional	6
HP:0100852	HP:0000739	Anxiety	1	POGZ CL E G H	23126	18801	OMIM:616364	White-Sutton syndrome		35
HP:0100852	HP:0000739	Anxiety	1	POLG CL E G H	5428	9179	ORPHA:254892	Autosomal dominant progressive external ophthalmoplegia	HP:0040283 - Occasional	464
HP:0100852	HP:0000739	Anxiety	1	POLG2 CL E G H	11232	9180	ORPHA:254892	Autosomal dominant progressive external ophthalmoplegia	HP:0040283 - Occasional	45
HP:0100852	HP:0000739	Anxiety	1	POLG2 CL E G H	11232	9180	OMIM:619425	MITOCHONDRIAL DNA DEPLETION SYNDROME 16B (NEUROOPHTHALMIC TYPE); MTDPS16B		45
HP:0100852	HP:0000739	Anxiety	1	PON1 CL E G H	5444	9204	ORPHA:803	Amyotrophic lateral sclerosis	HP:0040282 - Frequent	4
HP:0100852	HP:0000739	Anxiety	1	PON2 CL E G H	5445	9205	ORPHA:803	Amyotrophic lateral sclerosis	HP:0040282 - Frequent	2
HP:0100852	HP:0000739	Anxiety	1	PON3 CL E G H	5446	9206	ORPHA:803	Amyotrophic lateral sclerosis	HP:0040282 - Frequent	1
HP:0100852	HP:0000739	Anxiety	1	PPARGC1A CL E G H	10891	9237	ORPHA:803	Amyotrophic lateral sclerosis	HP:0040282 - Frequent	1
HP:0100852	HP:0000739	Anxiety	1	PPM1D CL E G H	8493	9277	OMIM:617450	Intellectual developmental disorder with gastrointestinal difficulties and high pain threshold	.	22
HP:0100852	HP:0000739	Anxiety	1	PPOX CL E G H	5498	9280	ORPHA:79473	Porphyria variegata	HP:0040282 - Frequent	41
HP:0100852	HP:0000739	Anxiety	1	PPP1CB CL E G H	5500	9282	OMIM:617506	Noonan syndrome-like disorder with loose anagen hair 2		9
HP:0100852	HP:0000739	Anxiety	1	PPP2R2B CL E G H	5521	9305	OMIM:604326	Spinocerebellar ataxia 12	.	5
HP:0100852	HP:0000739	Anxiety	1	PQBP1 CL E G H	10084	9330	OMIM:309500	Renpenning syndrome	.	28
HP:0100852	HP:0000739	Anxiety	1	PRKAR1A CL E G H	5573	9388	ORPHA:1501	Adrenocortical carcinoma	HP:0040282 - Frequent	134
HP:0100852	HP:0025269	Panic attack	1	PRKAR1A CL E G H	5573	9388	ORPHA:1501	Adrenocortical carcinoma	HP:0040282 - Frequent	134
HP:0100852	HP:0000739	Anxiety	1	PRKAR1A CL E G H	5573	9388	OMIM:610489	Pigmented nodular adrenocortical disease, primary, 1	.	134
HP:0100852	HP:0000739	Anxiety	1	PRKAR1B CL E G H	5575	9390	ORPHA:412066	PRKAR1B-related neurodegenerative dementia with intermediate filaments	HP:0040282 - Frequent	2
HP:0100852	HP:0000739	Anxiety	1	PRKN CL E G H	5071	8607	ORPHA:2828	Young-onset Parkinson disease	HP:0040283 - Occasional	138
HP:0100852	HP:0025269	Panic attack	1	PRKN CL E G H	5071	8607	ORPHA:2828	Young-onset Parkinson disease	HP:0040283 - Occasional	138
HP:0100852	HP:0000739	Anxiety	1	PRNP CL E G H	5621	9449	OMIM:123400	Creutzfeldt-Jakob disease	.	69
HP:0100852	HP:0000739	Anxiety	1	PRNP CL E G H	5621	9449	ORPHA:280397	Familial Alzheimer-like prion disease	HP:0040281 - Very frequent	69
HP:0100852	HP:0000739	Anxiety	1	PRNP CL E G H	5621	9449	OMIM:603218	Huntington disease-like 1	.	69
HP:0100852	HP:0000739	Anxiety	1	PRNP CL E G H	5621	9449	ORPHA:282166	Inherited Creutzfeldt-Jakob disease	HP:0040282 - Frequent	69
HP:0100852	HP:0000739	Anxiety	1	PROK2 CL E G H	60675	18455	ORPHA:432	Normosmic congenital hypogonadotropic hypogonadism	HP:0040282 - Frequent	9
HP:0100852	HP:0000739	Anxiety	1	PROKR2 CL E G H	128674	15836	ORPHA:432	Normosmic congenital hypogonadotropic hypogonadism	HP:0040282 - Frequent	34
HP:0100852	HP:0000739	Anxiety	1	PRPH CL E G H	5630	9461	ORPHA:803	Amyotrophic lateral sclerosis	HP:0040282 - Frequent	25
HP:0100852	HP:0000739	Anxiety	1	PRR12 CL E G H	57479	29217	OMIM:619539	NEUROOCULAR SYNDROME; NOC		1
HP:0100852	HP:0000739	Anxiety	1	PRRT2 CL E G H	112476	30500	OMIM:602066	Convulsions, familial infantile, with paroxysmal choreoathetosis	.	94
HP:0100852	HP:0000739	Anxiety	1	PSEN1 CL E G H	5663	9508	ORPHA:100070	Progressive non-fluent aphasia	HP:0040282 - Frequent	241
HP:0100852	HP:0000739	Anxiety	1	PSMD12 CL E G H	5718	9557	ORPHA:529962	17q24.2 microdeletion syndrome	HP:0040282 - Frequent	4
HP:0100852	HP:0000739	Anxiety	1	PTCH1 CL E G H	5727	9585	ORPHA:93925	Alobar holoprosencephaly	HP:0040282 - Frequent	665
HP:0100852	HP:0000739	Anxiety	1	PTCH1 CL E G H	5727	9585	ORPHA:93924	Lobar holoprosencephaly	HP:0040282 - Frequent	665
HP:0100852	HP:0000739	Anxiety	1	PTCH1 CL E G H	5727	9585	ORPHA:93926	Midline interhemispheric variant of holoprosencephaly	HP:0040282 - Frequent	665
HP:0100852	HP:0000739	Anxiety	1	PTCH1 CL E G H	5727	9585	ORPHA:220386	Semilobar holoprosencephaly	HP:0040282 - Frequent	665
HP:0100852	HP:0000739	Anxiety	1	PURA CL E G H	5813	9701	ORPHA:438216	PURA-related severe neonatal hypotonia-seizures-encephalopathy syndrome due to a point mutation	HP:0040283 - Occasional	53
HP:0100852	HP:0000739	Anxiety	1	RAD21 CL E G H	5885	9811	ORPHA:199	Cornelia de Lange syndrome	HP:0040282 - Frequent	25
HP:0100852	HP:0000739	Anxiety	1	RAI1 CL E G H	10743	9834	ORPHA:1713	17p11.2 microduplication syndrome	HP:0040282 - Frequent	150
HP:0100852	HP:0000739	Anxiety	1	RAI1 CL E G H	10743	9834	ORPHA:819	Smith-Magenis syndrome	HP:0040281 - Very frequent	150
HP:0100852	HP:0000739	Anxiety	1	RET CL E G H	5979	9967	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma		572
HP:0100852	HP:0025269	Panic attack	1	RET CL E G H	5979	9967	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma	HP:0040283 - Occasional	572
HP:0100852	HP:0025269	Panic attack	1	RET CL E G H	5979	9967	ORPHA:276621	Sporadic pheochromocytoma/secreting paraganglioma	HP:0040283 - Occasional	572
HP:0100852	HP:0000739	Anxiety	1	RET CL E G H	5979	9967	ORPHA:276621	Sporadic pheochromocytoma/secreting paraganglioma		572
HP:0100852	HP:0000739	Anxiety	1	RFC2 CL E G H	5982	9970	ORPHA:904	Williams syndrome	HP:0040281 - Very frequent
HP:0100852	HP:0000739	Anxiety	1	RIMS2 CL E G H	9699	17283	OMIM:618970	CONE-ROD SYNAPTIC DISORDER SYNDROME, CONGENITAL NONPROGRESSIVE; CRSDS		2
HP:0100852	HP:0000739	Anxiety	1	RLIM CL E G H	51132	13429	OMIM:300978	Tonne-Kalscheuer syndrome	.	7
HP:0100852	HP:0000739	Anxiety	1	RNF125 CL E G H	54941	21150	OMIM:616260	Tenorio syndrome	.	5
HP:0100852	HP:0000739	Anxiety	1	RPS20 CL E G H	6224	10405	ORPHA:440437	Familial colorectal cancer Type X	HP:0040282 - Frequent	1
HP:0100852	HP:0000739	Anxiety	1	RREB1 CL E G H	6239	10449	ORPHA:567	22q11.2 deletion syndrome	HP:0040283 - Occasional
HP:0100852	HP:0000739	Anxiety	1	RRM2B CL E G H	50484	17296	ORPHA:254892	Autosomal dominant progressive external ophthalmoplegia	HP:0040283 - Occasional	125
HP:0100852	HP:0000739	Anxiety	1	RRM2B CL E G H	50484	17296	OMIM:613077	Progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal dominant 5	HP:0040283 - Occasional	125
HP:0100852	HP:0000739	Anxiety	1	SATB2 CL E G H	23314	21637	ORPHA:251019	2q32q33 microdeletion syndrome	HP:0040283 - Occasional	34
HP:0100852	HP:0000739	Anxiety	1	SCN1A CL E G H	6323	10585	ORPHA:33069	Dravet syndrome	HP:0040282 - Frequent	1053
HP:0100852	HP:0000739	Anxiety	1	SCN1A CL E G H	6323	10585	ORPHA:36387	Generalized epilepsy with febrile seizures-plus	HP:0040284 - Very rare	1053
HP:0100852	HP:0000739	Anxiety	1	SCN1B CL E G H	6324	10586	ORPHA:33069	Dravet syndrome	HP:0040282 - Frequent	126
HP:0100852	HP:0000739	Anxiety	1	SCN1B CL E G H	6324	10586	ORPHA:36387	Generalized epilepsy with febrile seizures-plus	HP:0040284 - Very rare	126
HP:0100852	HP:0000739	Anxiety	1	SCN2A CL E G H	6326	10588	ORPHA:33069	Dravet syndrome	HP:0040282 - Frequent	427
HP:0100852	HP:0000739	Anxiety	1	SCN2A CL E G H	6326	10588	ORPHA:36387	Generalized epilepsy with febrile seizures-plus	HP:0040284 - Very rare	427
HP:0100852	HP:0000739	Anxiety	1	SCN9A CL E G H	6335	10597	ORPHA:33069	Dravet syndrome	HP:0040282 - Frequent	318
HP:0100852	HP:0000739	Anxiety	1	SCN9A CL E G H	6335	10597	ORPHA:36387	Generalized epilepsy with febrile seizures-plus	HP:0040284 - Very rare	318
HP:0100852	HP:0025269	Panic attack	1	SDHA CL E G H	6389	10680	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma	HP:0040283 - Occasional	304
HP:0100852	HP:0000739	Anxiety	1	SDHA CL E G H	6389	10680	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma		304
HP:0100852	HP:0025269	Panic attack	1	SDHAF2 CL E G H	54949	26034	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma	HP:0040283 - Occasional	55
HP:0100852	HP:0000739	Anxiety	1	SDHAF2 CL E G H	54949	26034	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma		55
HP:0100852	HP:0025269	Panic attack	1	SDHB CL E G H	6390	10681	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma	HP:0040283 - Occasional	237
HP:0100852	HP:0000739	Anxiety	1	SDHB CL E G H	6390	10681	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma		237
HP:0100852	HP:0000739	Anxiety	1	SDHB CL E G H	6390	10681	OMIM:115310	Paragangliomas 4		237
HP:0100852	HP:0025269	Panic attack	1	SDHB CL E G H	6390	10681	ORPHA:276621	Sporadic pheochromocytoma/secreting paraganglioma	HP:0040283 - Occasional	237
HP:0100852	HP:0000739	Anxiety	1	SDHB CL E G H	6390	10681	ORPHA:276621	Sporadic pheochromocytoma/secreting paraganglioma		237
HP:0100852	HP:0025269	Panic attack	1	SDHC CL E G H	6391	10682	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma	HP:0040283 - Occasional	147
HP:0100852	HP:0000739	Anxiety	1	SDHC CL E G H	6391	10682	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma		147
HP:0100852	HP:0000739	Anxiety	1	SDHC CL E G H	6391	10682	OMIM:605373	Paragangliomas 3		147
HP:0100852	HP:0025269	Panic attack	1	SDHD CL E G H	6392	10683	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma	HP:0040283 - Occasional	129
HP:0100852	HP:0000739	Anxiety	1	SDHD CL E G H	6392	10683	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma		129
HP:0100852	HP:0000739	Anxiety	1	SDHD CL E G H	6392	10683	OMIM:168000	Paragangliomas 1		129
HP:0100852	HP:0000739	Anxiety	1	SDHD CL E G H	6392	10683	ORPHA:276621	Sporadic pheochromocytoma/secreting paraganglioma		129
HP:0100852	HP:0025269	Panic attack	1	SDHD CL E G H	6392	10683	ORPHA:276621	Sporadic pheochromocytoma/secreting paraganglioma	HP:0040283 - Occasional	129
HP:0100852	HP:0000739	Anxiety	1	SEC24C CL E G H	9632	10705	ORPHA:567	22q11.2 deletion syndrome	HP:0040283 - Occasional
HP:0100852	HP:0000739	Anxiety	1	SEMA4A CL E G H	64218	10729	ORPHA:440437	Familial colorectal cancer Type X	HP:0040282 - Frequent	48
HP:0100852	HP:0000739	Anxiety	1	SERPINA1 CL E G H	5265	8941	ORPHA:586	Cystic fibrosis		131
HP:0100852	HP:0000739	Anxiety	1	SETBP1 CL E G H	26040	15573	OMIM:616078	Mental retardation, autosomal dominant 29		143
HP:0100852	HP:0000739	Anxiety	1	SETD1A CL E G H	9739	29010	OMIM:619056	NEURODEVELOPMENTAL DISORDER WITH SPEECH IMPAIRMENT AND DYSMORPHIC FACIES; NEDSID		6
HP:0100852	HP:0000739	Anxiety	1	SETD1B CL E G H	23067	29187	OMIM:619000	INTELLECTUAL DEVELOPMENTAL DISORDER WITH SEIZURES AND LANGUAGE DELAY; IDDSELD
HP:0100852	HP:0000739	Anxiety	1	SETD2 CL E G H	29072	18420	OMIM:616831	Luscan-Lumish syndrome	.	60
HP:0100852	HP:0000739	Anxiety	1	SETD2 CL E G H	29072	18420	ORPHA:821	Sotos syndrome	HP:0040283 - Occasional	60
HP:0100852	HP:0000739	Anxiety	1	SETD5 CL E G H	55209	25566	ORPHA:404440	Intellectual disability-facial dysmorphism syndrome due to SETD5 haploinsufficiency	HP:0040283 - Occasional	43
HP:0100852	HP:0000739	Anxiety	1	SGCE CL E G H	8910	10808	OMIM:159900	Dystonia 11, myoclonic	.	49
HP:0100852	HP:0000756	Agoraphobia	1	SGCE CL E G H	8910	10808	OMIM:159900	Dystonia 11, myoclonic	.	49
HP:0100852	HP:0025269	Panic attack	1	SGCE CL E G H	8910	10808	ORPHA:36899	Myoclonus-dystonia syndrome	HP:0040282 - Frequent	49
HP:0100852	HP:0000739	Anxiety	1	SGCE CL E G H	8910	10808	ORPHA:36899	Myoclonus-dystonia syndrome	HP:0040282 - Frequent	49
HP:0100852	HP:0000739	Anxiety	1	SHH CL E G H	6469	10848	ORPHA:93925	Alobar holoprosencephaly	HP:0040282 - Frequent	67
HP:0100852	HP:0000739	Anxiety	1	SHH CL E G H	6469	10848	ORPHA:93924	Lobar holoprosencephaly	HP:0040282 - Frequent	67
HP:0100852	HP:0000739	Anxiety	1	SHH CL E G H	6469	10848	ORPHA:93926	Midline interhemispheric variant of holoprosencephaly	HP:0040282 - Frequent	67
HP:0100852	HP:0000739	Anxiety	1	SHH CL E G H	6469	10848	ORPHA:220386	Semilobar holoprosencephaly	HP:0040282 - Frequent	67
HP:0100852	HP:0000739	Anxiety	1	SHQ1 CL E G H	55164	25543	OMIM:619922
HP:0100852	HP:0000739	Anxiety	1	SIN3A CL E G H	25942	19353	OMIM:613406	Witteveen-Kolk syndrome		9
HP:0100852	HP:0000739	Anxiety	1	SIX3 CL E G H	6496	10889	ORPHA:93925	Alobar holoprosencephaly	HP:0040282 - Frequent	32
HP:0100852	HP:0000739	Anxiety	1	SIX3 CL E G H	6496	10889	ORPHA:93924	Lobar holoprosencephaly	HP:0040282 - Frequent	32
HP:0100852	HP:0000739	Anxiety	1	SIX3 CL E G H	6496	10889	ORPHA:93926	Midline interhemispheric variant of holoprosencephaly	HP:0040282 - Frequent	32
HP:0100852	HP:0000739	Anxiety	1	SIX3 CL E G H	6496	10889	ORPHA:220386	Semilobar holoprosencephaly	HP:0040282 - Frequent	32
HP:0100852	HP:0000739	Anxiety	1	SLC11A1 CL E G H	6556	10907	ORPHA:586	Cystic fibrosis		2
HP:0100852	HP:0000739	Anxiety	1	SLC25A11 CL E G H	8402	10981	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma
HP:0100852	HP:0025269	Panic attack	1	SLC25A11 CL E G H	8402	10981	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma	HP:0040283 - Occasional
HP:0100852	HP:0000739	Anxiety	1	SLC25A4 CL E G H	291	10990	ORPHA:254892	Autosomal dominant progressive external ophthalmoplegia	HP:0040283 - Occasional	68
HP:0100852	HP:0000739	Anxiety	1	SLC26A9 CL E G H	115019	14469	ORPHA:586	Cystic fibrosis		5
HP:0100852	HP:0000739	Anxiety	1	SLC2A1 CL E G H	6513	11005	ORPHA:64280	Childhood absence epilepsy	HP:0040283 - Occasional	255
HP:0100852	HP:0000739	Anxiety	1	SLC2A3 CL E G H	6515	11007	ORPHA:399	Huntington disease	HP:0040282 - Frequent	1
HP:0100852	HP:0000739	Anxiety	1	SLC35C1 CL E G H	55343	20197	OMIM:266265	Congenital disorder of glycosylation, type IIc		71
HP:0100852	HP:0000739	Anxiety	1	SLC45A1 CL E G H	50651	17939	OMIM:617532	Intellectual developmental disorder with neuropsychiatric features	.	2
HP:0100852	HP:0000739	Anxiety	1	SLC6A14 CL E G H	11254	11047	ORPHA:586	Cystic fibrosis
HP:0100852	HP:0000739	Anxiety	1	SLC6A19 CL E G H	340024	27960	ORPHA:2116	Hartnup disease	HP:0040281 - Very frequent	12
HP:0100852	HP:0000739	Anxiety	1	SLC6A4 CL E G H	6532	11050	OMIM:164230	Obsessive-Compulsive disorder 1		52
HP:0100852	HP:0000739	Anxiety	1	SLC7A6OS CL E G H	84138	25807	OMIM:619191	EPILEPSY, PROGRESSIVE MYOCLONIC, 12; EPM12
HP:0100852	HP:0000739	Anxiety	1	SLC9A3 CL E G H	6550	11073	ORPHA:586	Cystic fibrosis		7
HP:0100852	HP:0025269	Panic attack	1	SMC1A CL E G H	8243	11111	ORPHA:3095	Atypical Rett syndrome	HP:0040283 - Occasional	135
HP:0100852	HP:0000739	Anxiety	1	SMC1A CL E G H	8243	11111	ORPHA:199	Cornelia de Lange syndrome	HP:0040282 - Frequent	135
HP:0100852	HP:0000739	Anxiety	1	SMC1A CL E G H	8243	11111	ORPHA:220386	Semilobar holoprosencephaly	HP:0040282 - Frequent	135
HP:0100852	HP:0000739	Anxiety	1	SMC3 CL E G H	9126	2468	ORPHA:199	Cornelia de Lange syndrome	HP:0040282 - Frequent	91
HP:0100852	HP:0025269	Panic attack	1	SNCA CL E G H	6622	11138	ORPHA:2828	Young-onset Parkinson disease	HP:0040283 - Occasional	65
HP:0100852	HP:0000739	Anxiety	1	SNCA CL E G H	6622	11138	ORPHA:2828	Young-onset Parkinson disease	HP:0040283 - Occasional	65
HP:0100852	HP:0000739	Anxiety	1	SNRPN CL E G H	6638	11164	ORPHA:177907	Prader-Willi syndrome due to translocation	HP:0040283 - Occasional	37
HP:0100852	HP:0000739	Anxiety	1	SOD1 CL E G H	6647	11179	ORPHA:803	Amyotrophic lateral sclerosis	HP:0040282 - Frequent	53
HP:0100852	HP:0000739	Anxiety	1	SOX5 CL E G H	6660	11201	ORPHA:313892	Developmental and speech delay due to SOX5 deficiency	HP:0040282 - Frequent	11
HP:0100852	HP:0000739	Anxiety	1	SOX5 CL E G H	6660	11201	OMIM:616803	Lamb-Shaffer syndrome		11
HP:0100852	HP:0025269	Panic attack	1	SPART CL E G H	23111	18514	ORPHA:101000	Autosomal recessive spastic paraplegia type 20	HP:0040283 - Occasional	66
HP:0100852	HP:0000739	Anxiety	1	SPART CL E G H	23111	18514	ORPHA:101000	Autosomal recessive spastic paraplegia type 20	HP:0040283 - Occasional	66
HP:0100852	HP:0025269	Panic attack	1	SPECC1L CL E G H	23384	29022	OMIM:145420	Hypertelorism, Teebi type		6
HP:0100852	HP:0000739	Anxiety	1	SPECC1L CL E G H	23384	29022	OMIM:145420	Hypertelorism, Teebi type	.	6
HP:0100852	HP:0000739	Anxiety	1	SPRY4 CL E G H	81848	15533	ORPHA:432	Normosmic congenital hypogonadotropic hypogonadism	HP:0040282 - Frequent	5
HP:0100852	HP:0000739	Anxiety	1	SPTBN1 CL E G H	6711	11275	OMIM:619475	DEVELOPMENTAL DELAY, IMPAIRED SPEECH, AND BEHAVIORAL ABNORMALITIES; DDISBA
HP:0100852	HP:0000739	Anxiety	1	SQSTM1 CL E G H	8878	11280	ORPHA:803	Amyotrophic lateral sclerosis	HP:0040282 - Frequent	62
HP:0100852	HP:0000739	Anxiety	1	SRCAP CL E G H	10847	16974	ORPHA:2044	Floating-Harbor syndrome	HP:0040283 - Occasional	138
HP:0100852	HP:0000739	Anxiety	1	SRPX2 CL E G H	27286	30668	ORPHA:1945	Rolandic epilepsy	HP:0040283 - Occasional	50
HP:0100852	HP:0000739	Anxiety	1	STAG2 CL E G H	10735	11355	ORPHA:93925	Alobar holoprosencephaly	HP:0040282 - Frequent	1
HP:0100852	HP:0000739	Anxiety	1	STAG2 CL E G H	10735	11355	ORPHA:220386	Semilobar holoprosencephaly	HP:0040282 - Frequent	1
HP:0100852	HP:0000739	Anxiety	1	STAG2 CL E G H	10735	11355	ORPHA:521258	Xq25 microduplication syndrome	HP:0040282 - Frequent	1
HP:0100852	HP:0000739	Anxiety	1	STEEP1 CL E G H	63932	26239	OMIM:301013	MENTAL RETARDATION, X-LINKED 107; MRX107
HP:0100852	HP:0000739	Anxiety	1	STIL CL E G H	6491	10879	ORPHA:93925	Alobar holoprosencephaly	HP:0040282 - Frequent	99
HP:0100852	HP:0000739	Anxiety	1	STIL CL E G H	6491	10879	ORPHA:93924	Lobar holoprosencephaly	HP:0040282 - Frequent	99
HP:0100852	HP:0000739	Anxiety	1	STIL CL E G H	6491	10879	ORPHA:93926	Midline interhemispheric variant of holoprosencephaly	HP:0040282 - Frequent	99
HP:0100852	HP:0000739	Anxiety	1	STIL CL E G H	6491	10879	ORPHA:220386	Semilobar holoprosencephaly	HP:0040282 - Frequent	99
HP:0100852	HP:0000739	Anxiety	1	STUB1 CL E G H	10273	11427	OMIM:618093	SPINOCEREBELLAR ATAXIA 48; SCA48		14
HP:0100852	HP:0000739	Anxiety	1	STX16 CL E G H	8675	11431	ORPHA:94089	Pseudohypoparathyroidism type 1B	HP:0040283 - Occasional	86
HP:0100852	HP:0000739	Anxiety	1	STX1A CL E G H	6804	11433	ORPHA:586	Cystic fibrosis
HP:0100852	HP:0000739	Anxiety	1	STX1A CL E G H	6804	11433	ORPHA:904	Williams syndrome	HP:0040281 - Very frequent
HP:0100852	HP:0000739	Anxiety	1	STX1B CL E G H	112755	18539	ORPHA:36387	Generalized epilepsy with febrile seizures-plus	HP:0040284 - Very rare	9
HP:0100852	HP:0025269	Panic attack	1	SYNJ1 CL E G H	8867	11503	ORPHA:2828	Young-onset Parkinson disease	HP:0040283 - Occasional	9
HP:0100852	HP:0000739	Anxiety	1	SYNJ1 CL E G H	8867	11503	ORPHA:2828	Young-onset Parkinson disease	HP:0040283 - Occasional	9
HP:0100852	HP:0000739	Anxiety	1	TAC3 CL E G H	6866	11521	ORPHA:432	Normosmic congenital hypogonadotropic hypogonadism	HP:0040282 - Frequent	6
HP:0100852	HP:0000739	Anxiety	1	TACR3 CL E G H	6870	11528	ORPHA:432	Normosmic congenital hypogonadotropic hypogonadism	HP:0040282 - Frequent	34
HP:0100852	HP:0000739	Anxiety	1	TAF1 CL E G H	6872	11535	OMIM:300966	MENTAL RETARDATION, X-LINKED, SYNDROMIC 33; MRXS33		21
HP:0100852	HP:0000739	Anxiety	1	TAF15 CL E G H	8148	11547	ORPHA:803	Amyotrophic lateral sclerosis	HP:0040282 - Frequent
HP:0100852	HP:0000739	Anxiety	1	TANC2 CL E G H	26115	30212	OMIM:618906	INTELLECTUAL DEVELOPMENTAL DISORDER WITH AUTISTIC FEATURES AND LANGUAGE DELAY, WITH OR WITHOUT SEIZURES; IDDALDS
HP:0100852	HP:0000739	Anxiety	1	TARDBP CL E G H	23435	11571	ORPHA:803	Amyotrophic lateral sclerosis	HP:0040282 - Frequent	65
HP:0100852	HP:0000739	Anxiety	1	TBK1 CL E G H	29110	11584	ORPHA:803	Amyotrophic lateral sclerosis	HP:0040282 - Frequent	20
HP:0100852	HP:0000739	Anxiety	1	TBL2 CL E G H	26608	11586	ORPHA:904	Williams syndrome	HP:0040281 - Very frequent
HP:0100852	HP:0000739	Anxiety	1	TBX1 CL E G H	6899	11592	ORPHA:567	22q11.2 deletion syndrome	HP:0040283 - Occasional	32
HP:0100852	HP:0000739	Anxiety	1	TBX1 CL E G H	6899	11592	ORPHA:1727	22q11.2 duplication syndrome	HP:0040283 - Occasional	32
HP:0100852	HP:0000739	Anxiety	1	TCF12 CL E G H	6938	11623	OMIM:619718	HYPOGONADOTROPIC HYPOGONADISM 26 WITH OR WITHOUT ANOSMIA; HH26		28
HP:0100852	HP:0000739	Anxiety	1	TCF20 CL E G H	6942	11631	OMIM:618430	Developmental delay with variable intellectual impairment and behavioral abnormalities	.	1
HP:0100852	HP:0000739	Anxiety	1	TDGF1 CL E G H	6997	11701	ORPHA:93925	Alobar holoprosencephaly	HP:0040282 - Frequent	1
HP:0100852	HP:0000739	Anxiety	1	TDGF1 CL E G H	6997	11701	ORPHA:93924	Lobar holoprosencephaly	HP:0040282 - Frequent	1
HP:0100852	HP:0000739	Anxiety	1	TDGF1 CL E G H	6997	11701	ORPHA:93926	Midline interhemispheric variant of holoprosencephaly	HP:0040282 - Frequent	1
HP:0100852	HP:0000739	Anxiety	1	TDGF1 CL E G H	6997	11701	ORPHA:220386	Semilobar holoprosencephaly	HP:0040282 - Frequent	1
HP:0100852	HP:0000739	Anxiety	1	TERT CL E G H	7015	11730	ORPHA:1501	Adrenocortical carcinoma	HP:0040282 - Frequent	238
HP:0100852	HP:0025269	Panic attack	1	TERT CL E G H	7015	11730	ORPHA:1501	Adrenocortical carcinoma	HP:0040282 - Frequent	238
HP:0100852	HP:0000739	Anxiety	1	TET3 CL E G H	200424	28313	OMIM:618798	BECK-FAHRNER SYNDROME; BEFAHRS
HP:0100852	HP:0000739	Anxiety	1	TGFB1 CL E G H	7040	11766	ORPHA:586	Cystic fibrosis		13
HP:0100852	HP:0000739	Anxiety	1	TGFBR2 CL E G H	7048	11773	ORPHA:144	Lynch syndrome	HP:0040282 - Frequent	253
HP:0100852	HP:0000739	Anxiety	1	TGIF1 CL E G H	7050	11776	ORPHA:93925	Alobar holoprosencephaly	HP:0040282 - Frequent	32
HP:0100852	HP:0000739	Anxiety	1	TGIF1 CL E G H	7050	11776	ORPHA:93924	Lobar holoprosencephaly	HP:0040282 - Frequent	32
HP:0100852	HP:0000739	Anxiety	1	TGIF1 CL E G H	7050	11776	ORPHA:93926	Midline interhemispheric variant of holoprosencephaly	HP:0040282 - Frequent	32
HP:0100852	HP:0000739	Anxiety	1	TGIF1 CL E G H	7050	11776	ORPHA:220386	Semilobar holoprosencephaly	HP:0040282 - Frequent	32
HP:0100852	HP:0000739	Anxiety	1	THOC2 CL E G H	57187	19073	OMIM:300957	Mental retardation, X-linked 12/35		5
HP:0100852	HP:0000739	Anxiety	1	THOC2 CL E G H	57187	19073	ORPHA:457240	X-linked intellectual disability-short stature-overweight syndrome	HP:0040283 - Occasional	5
HP:0100852	HP:0000739	Anxiety	1	TLK2 CL E G H	11011	11842	OMIM:618050	Mental retardation, autosomal dominant 57	.	1
HP:0100852	HP:0000739	Anxiety	1	TLR7 CL E G H	51284	15631	OMIM:301080
HP:0100852	HP:0000739	Anxiety	1	TMCO1 CL E G H	54499	18188	OMIM:213980	Craniofacial dysmorphism, skeletal anomalies, and mental retardation syndrome	HP:0040283 - Occasional	6
HP:0100852	HP:0000739	Anxiety	1	TMEM106B CL E G H	54664	22407	ORPHA:100070	Progressive non-fluent aphasia	HP:0040282 - Frequent
HP:0100852	HP:0025269	Panic attack	1	TMEM127 CL E G H	55654	26038	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma	HP:0040283 - Occasional	131
HP:0100852	HP:0000739	Anxiety	1	TMEM127 CL E G H	55654	26038	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma		131
HP:0100852	HP:0000739	Anxiety	1	TMEM147 CL E G H	10430	30414	OMIM:620075
HP:0100852	HP:0000739	Anxiety	1	TMEM270 CL E G H	135886	23018	ORPHA:904	Williams syndrome	HP:0040281 - Very frequent
HP:0100852	HP:0000739	Anxiety	1	TOR1A CL E G H	1861	3098	ORPHA:36899	Myoclonus-dystonia syndrome	HP:0040282 - Frequent	47
HP:0100852	HP:0025269	Panic attack	1	TOR1A CL E G H	1861	3098	ORPHA:36899	Myoclonus-dystonia syndrome	HP:0040282 - Frequent	47
HP:0100852	HP:0025269	Panic attack	1	TP53 CL E G H	7157	11998	ORPHA:1501	Adrenocortical carcinoma	HP:0040282 - Frequent	911
HP:0100852	HP:0000739	Anxiety	1	TP53 CL E G H	7157	11998	ORPHA:1501	Adrenocortical carcinoma	HP:0040282 - Frequent	911
HP:0100852	HP:0025269	Panic attack	1	TP53 CL E G H	7157	11998	ORPHA:96253	Cushing disease		911
HP:0100852	HP:0000739	Anxiety	1	TREM2 CL E G H	54209	17761	ORPHA:803	Amyotrophic lateral sclerosis	HP:0040282 - Frequent	31
HP:0100852	HP:0000739	Anxiety	1	TREM2 CL E G H	54209	17761	ORPHA:100070	Progressive non-fluent aphasia	HP:0040282 - Frequent	31
HP:0100852	HP:0000739	Anxiety	1	TREX1 CL E G H	11277	12269	ORPHA:247691	Retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations	HP:0040283 - Occasional	56
HP:0100852	HP:0000739	Anxiety	1	TRIP12 CL E G H	9320	12306	OMIM:617752	Mental retardation, autosomal dominant 49		2
HP:0100852	HP:0000739	Anxiety	1	TRNF CL E G H	4558	7481	ORPHA:550	MELAS	HP:0040282 - Frequent
HP:0100852	HP:0000739	Anxiety	1	TRNH CL E G H	4564	7487	ORPHA:550	MELAS	HP:0040282 - Frequent
HP:0100852	HP:0000739	Anxiety	1	TRNL1 CL E G H	4567	7490	ORPHA:550	MELAS	HP:0040282 - Frequent
HP:0100852	HP:0000739	Anxiety	1	TRNQ CL E G H	4572	7495	ORPHA:550	MELAS	HP:0040282 - Frequent
HP:0100852	HP:0000739	Anxiety	1	TRNS1 CL E G H	4574	7497	ORPHA:550	MELAS	HP:0040282 - Frequent
HP:0100852	HP:0000739	Anxiety	1	TRNS2 CL E G H	4575	7498	ORPHA:550	MELAS	HP:0040282 - Frequent
HP:0100852	HP:0000739	Anxiety	1	TRNS2 CL E G H	4575	7498	ORPHA:231183	Usher syndrome type 3	HP:0040283 - Occasional
HP:0100852	HP:0000739	Anxiety	1	TRNW CL E G H	4578	7501	ORPHA:550	MELAS	HP:0040282 - Frequent
HP:0100852	HP:0000739	Anxiety	1	TSC1 CL E G H	7248	12362	ORPHA:805	Tuberous sclerosis complex	HP:0040283 - Occasional	1090
HP:0100852	HP:0000739	Anxiety	1	TSC2 CL E G H	7249	12363	ORPHA:805	Tuberous sclerosis complex	HP:0040283 - Occasional	2738
HP:0100852	HP:0000739	Anxiety	1	TTC19 CL E G H	54902	26006	OMIM:615157	Mitochondrial complex III deficiency, nuclear type 2	.	88
HP:0100852	HP:0000739	Anxiety	1	TWNK CL E G H	56652	1160	ORPHA:254892	Autosomal dominant progressive external ophthalmoplegia	HP:0040283 - Occasional	113
HP:0100852	HP:0000739	Anxiety	1	UBQLN2 CL E G H	29978	12509	ORPHA:803	Amyotrophic lateral sclerosis	HP:0040282 - Frequent	20
HP:0100852	HP:0000739	Anxiety	1	UCHL1 CL E G H	7345	12513	ORPHA:2828	Young-onset Parkinson disease	HP:0040283 - Occasional	21
HP:0100852	HP:0025269	Panic attack	1	UCHL1 CL E G H	7345	12513	ORPHA:2828	Young-onset Parkinson disease	HP:0040283 - Occasional	21
HP:0100852	HP:0000739	Anxiety	1	UFD1 CL E G H	7353	12520	ORPHA:567	22q11.2 deletion syndrome	HP:0040283 - Occasional
HP:0100852	HP:0000739	Anxiety	1	UNC13A CL E G H	23025	23150	ORPHA:803	Amyotrophic lateral sclerosis	HP:0040282 - Frequent	1
HP:0100852	HP:0000739	Anxiety	1	UQCRC1 CL E G H	7384	12585	OMIM:619279	PARKINSONISM WITH POLYNEUROPATHY; PKNPY
HP:0100852	HP:0000739	Anxiety	1	USH1C CL E G H	10083	12597	ORPHA:231169	Usher syndrome type 1	HP:0040283 - Occasional	173
HP:0100852	HP:0000739	Anxiety	1	USH1G CL E G H	124590	16356	ORPHA:231169	Usher syndrome type 1	HP:0040283 - Occasional	78
HP:0100852	HP:0000739	Anxiety	1	USH2A CL E G H	7399	12601	ORPHA:231178	Usher syndrome type 2	HP:0040283 - Occasional	777
HP:0100852	HP:0025269	Panic attack	1	USP48 CL E G H	84196	18533	ORPHA:96253	Cushing disease		1
HP:0100852	HP:0025269	Panic attack	1	USP8 CL E G H	9101	12631	ORPHA:96253	Cushing disease		7
HP:0100852	HP:0000739	Anxiety	1	VAPB CL E G H	9217	12649	ORPHA:803	Amyotrophic lateral sclerosis	HP:0040282 - Frequent	116
HP:0100852	HP:0000739	Anxiety	1	VCP CL E G H	7415	12666	ORPHA:329478	Adult-onset distal myopathy due to VCP mutation	HP:0040283 - Occasional	63
HP:0100852	HP:0000739	Anxiety	1	VCP CL E G H	7415	12666	ORPHA:803	Amyotrophic lateral sclerosis	HP:0040282 - Frequent	63
HP:0100852	HP:0000739	Anxiety	1	VCP CL E G H	7415	12666	ORPHA:100070	Progressive non-fluent aphasia	HP:0040282 - Frequent	63
HP:0100852	HP:0000739	Anxiety	1	VHL CL E G H	7428	12687	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma		490
HP:0100852	HP:0025269	Panic attack	1	VHL CL E G H	7428	12687	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma	HP:0040283 - Occasional	490
HP:0100852	HP:0000739	Anxiety	1	VHL CL E G H	7428	12687	ORPHA:276621	Sporadic pheochromocytoma/secreting paraganglioma		490
HP:0100852	HP:0025269	Panic attack	1	VHL CL E G H	7428	12687	ORPHA:276621	Sporadic pheochromocytoma/secreting paraganglioma	HP:0040283 - Occasional	490
HP:0100852	HP:0000739	Anxiety	1	VHL CL E G H	7428	12687	ORPHA:892	Von Hippel-Lindau disease	HP:0040283 - Occasional	490
HP:0100852	HP:0000739	Anxiety	1	VPS13A CL E G H	23230	1908	ORPHA:2388	Choreoacanthocytosis	HP:0040283 - Occasional	130
HP:0100852	HP:0000739	Anxiety	1	VPS13A CL E G H	23230	1908	OMIM:200150	CHOREOACANTHOCYTOSIS	.	130
HP:0100852	HP:0000739	Anxiety	1	VPS13C CL E G H	54832	23594	ORPHA:2828	Young-onset Parkinson disease	HP:0040283 - Occasional	8
HP:0100852	HP:0025269	Panic attack	1	VPS13C CL E G H	54832	23594	ORPHA:2828	Young-onset Parkinson disease	HP:0040283 - Occasional	8
HP:0100852	HP:0000739	Anxiety	1	VPS37D CL E G H	155382	18287	ORPHA:904	Williams syndrome	HP:0040281 - Very frequent
HP:0100852	HP:0000739	Anxiety	1	WAC CL E G H	51322	17327	OMIM:616708	Desanto-Shinawi syndrome	.	20
HP:0100852	HP:0000739	Anxiety	1	WAC CL E G H	51322	17327	ORPHA:284169	Facial dysmorphism-developmental delay-behavioral abnormalities syndrome due to 10p11.21p12.31 microdeletion	HP:0040282 - Frequent	20
HP:0100852	HP:0000739	Anxiety	1	WAC CL E G H	51322	17327	ORPHA:466950	Facial dysmorphism-developmental delay-behavioral abnormalities syndrome due to WAC point mutation	HP:0040282 - Frequent	20
HP:0100852	HP:0000739	Anxiety	1	WARS2 CL E G H	10352	12730	OMIM:619738	PARKINSONISM-DYSTONIA 3, CHILDHOOD-ONSET; PKDYS3		2
HP:0100852	HP:0000739	Anxiety	1	WDR11 CL E G H	55717	13831	ORPHA:432	Normosmic congenital hypogonadotropic hypogonadism	HP:0040282 - Frequent	10
HP:0100852	HP:0000739	Anxiety	1	WFS1 CL E G H	7466	12762	ORPHA:411590	Wolfram-like syndrome	HP:0040281 - Very frequent	389
HP:0100852	HP:0000739	Anxiety	1	WFS1 CL E G H	7466	12762	OMIM:614296	Wolfram-Like syndrome, autosomal dominant	HP:0040283 - Occasional	389
HP:0100852	HP:0000739	Anxiety	1	WHRN CL E G H	25861	16361	ORPHA:231178	Usher syndrome type 2	HP:0040283 - Occasional	155
HP:0100852	HP:0000739	Anxiety	1	XK CL E G H	7504	12811	OMIM:300842	Mcleod syndrome	.	8
HP:0100852	HP:0000739	Anxiety	1	YWHAG CL E G H	7532	12852	OMIM:617665	Epileptic encephalopathy, early infantile, 56	.
HP:0100852	HP:0000739	Anxiety	1	YY1 CL E G H	7528	12856	ORPHA:506358	Gabriele-de Vries syndrome	HP:0040283 - Occasional	7
HP:0100852	HP:0000739	Anxiety	1	YY1 CL E G H	7528	12856	OMIM:617557	Gabriele-De vries syndrome		7
HP:0100852	HP:0000739	Anxiety	1	YY1 CL E G H	7528	12856	ORPHA:97279	Insulinoma	HP:0040283 - Occasional	7
HP:0100852	HP:0000739	Anxiety	1	ZBTB20 CL E G H	26137	13503	OMIM:259050	Primrose syndrome		17
HP:0100852	HP:0000739	Anxiety	1	ZIC2 CL E G H	7546	12873	ORPHA:93925	Alobar holoprosencephaly	HP:0040282 - Frequent	34
HP:0100852	HP:0000739	Anxiety	1	ZIC2 CL E G H	7546	12873	ORPHA:93924	Lobar holoprosencephaly	HP:0040282 - Frequent	34
HP:0100852	HP:0000739	Anxiety	1	ZIC2 CL E G H	7546	12873	ORPHA:93926	Midline interhemispheric variant of holoprosencephaly	HP:0040282 - Frequent	34
HP:0100852	HP:0000739	Anxiety	1	ZIC2 CL E G H	7546	12873	ORPHA:220386	Semilobar holoprosencephaly	HP:0040282 - Frequent	34
HP:0100852	HP:0025269	Panic attack	1	ZNRF3 CL E G H	84133	18126	ORPHA:1501	Adrenocortical carcinoma	HP:0040282 - Frequent
HP:0100852	HP:0000739	Anxiety	1	ZNRF3 CL E G H	84133	18126	ORPHA:1501	Adrenocortical carcinoma	HP:0040282 - Frequent
HP:0100852	HP:0000740	Episodic paroxysmal anxiety	2	DLST CL E G H	1743	2911	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma	HP:0040282 - Frequent
HP:0100852	HP:0000740	Episodic paroxysmal anxiety	2	DNMT3A CL E G H	1788	2978	ORPHA:276621	Sporadic pheochromocytoma/secreting paraganglioma	HP:0040282 - Frequent	44
HP:0100852	HP:0000740	Episodic paroxysmal anxiety	2	EPAS1 CL E G H	2034	3374	ORPHA:276621	Sporadic pheochromocytoma/secreting paraganglioma	HP:0040282 - Frequent	112
HP:0100852	HP:0000740	Episodic paroxysmal anxiety	2	FH CL E G H	2271	3700	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma	HP:0040282 - Frequent	301
HP:0100852	HP:0000740	Episodic paroxysmal anxiety	2	KIF1B CL E G H	23095	16636	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma	HP:0040282 - Frequent	202
HP:0100852	HP:0000740	Episodic paroxysmal anxiety	2	MAX CL E G H	4149	6913	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma	HP:0040282 - Frequent	84
HP:0100852	HP:0000740	Episodic paroxysmal anxiety	2	MDH2 CL E G H	4191	6971	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma	HP:0040282 - Frequent	4
HP:0100852	HP:0000740	Episodic paroxysmal anxiety	2	NF1 CL E G H	4763	7765	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma	HP:0040282 - Frequent	1952
HP:0100852	HP:0000740	Episodic paroxysmal anxiety	2	RET CL E G H	5979	9967	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma	HP:0040282 - Frequent	572
HP:0100852	HP:0000740	Episodic paroxysmal anxiety	2	RET CL E G H	5979	9967	ORPHA:276621	Sporadic pheochromocytoma/secreting paraganglioma	HP:0040282 - Frequent	572
HP:0100852	HP:0000740	Episodic paroxysmal anxiety	2	SDHA CL E G H	6389	10680	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma	HP:0040282 - Frequent	304
HP:0100852	HP:0000740	Episodic paroxysmal anxiety	2	SDHAF2 CL E G H	54949	26034	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma	HP:0040282 - Frequent	55
HP:0100852	HP:0000740	Episodic paroxysmal anxiety	2	SDHB CL E G H	6390	10681	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma	HP:0040282 - Frequent	237
HP:0100852	HP:0000740	Episodic paroxysmal anxiety	2	SDHB CL E G H	6390	10681	OMIM:115310	Paragangliomas 4	.	237
HP:0100852	HP:0000740	Episodic paroxysmal anxiety	2	SDHB CL E G H	6390	10681	ORPHA:276621	Sporadic pheochromocytoma/secreting paraganglioma	HP:0040282 - Frequent	237
HP:0100852	HP:0000740	Episodic paroxysmal anxiety	2	SDHC CL E G H	6391	10682	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma	HP:0040282 - Frequent	147
HP:0100852	HP:0000740	Episodic paroxysmal anxiety	2	SDHC CL E G H	6391	10682	OMIM:605373	Paragangliomas 3	.	147
HP:0100852	HP:0000740	Episodic paroxysmal anxiety	2	SDHD CL E G H	6392	10683	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma	HP:0040282 - Frequent	129
HP:0100852	HP:0000740	Episodic paroxysmal anxiety	2	SDHD CL E G H	6392	10683	OMIM:168000	Paragangliomas 1	.	129
HP:0100852	HP:0000740	Episodic paroxysmal anxiety	2	SDHD CL E G H	6392	10683	ORPHA:276621	Sporadic pheochromocytoma/secreting paraganglioma	HP:0040282 - Frequent	129
HP:0100852	HP:0000740	Episodic paroxysmal anxiety	2	SLC25A11 CL E G H	8402	10981	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma	HP:0040282 - Frequent
HP:0100852	HP:0000740	Episodic paroxysmal anxiety	2	TMEM127 CL E G H	55654	26038	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma	HP:0040282 - Frequent	131
HP:0100852	HP:0000740	Episodic paroxysmal anxiety	2	VHL CL E G H	7428	12687	ORPHA:29072	Hereditary pheochromocytoma-paraganglioma	HP:0040282 - Frequent	490
HP:0100852	HP:0000740	Episodic paroxysmal anxiety	2	VHL CL E G H	7428	12687	ORPHA:276621	Sporadic pheochromocytoma/secreting paraganglioma	HP:0040282 - Frequent	490