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Examples Gene: MT-ND1, POLG, Region: M:1-1000 Variant: m.8993T>G, 1:g.10042757T>C rs3888511 MSCV_0000006, ClinVar: RCV000000015, Disease: Leigh syndrome, Phenotype: Retinopathy

MSeqDR Mitochondrial Disease Portal

*:HP: HPO terms, UMDF: 1= Disease, ND: NAMDC terms.
Most Studied CPEO, Complex I Deficiency, COXPD1, Leigh, LHON, MELAS, MERRF, Myopathy, SANDO

Disease Browser
Parent Node: Metabolism, Inborn Errors (D008661)
Parent Node: Mitochondrial Diseases (D028361)
..Starting node ..Mitochondrial Complex II Deficiency (C565375)
Child Nodes:
Sister Nodes:
..3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 Deficiency (C567784) L: 00105;
..Acyl-CoA Dehydrogenase Family, Member 9, Deficiency of (C567006) L: 00419;
..Ataxia and Polyneuropathy, Adult-Onset (C564020)
..Ataxia Neuropathy Spectrum (C579922)
..Bjornstad syndrome (C537633) L: 00084;
..Carbamoyl-Phosphate Synthase I Deficiency Disease (D020165) L: 00085;
..Carnitine Palmitoyltransferase II Deficiency, Late-Onset (C563461) L: 00486;
..Carnitine Palmitoyltransferase II Deficiency, Lethal Neonatal (C563463) L: 00487;
..Childhood Myocerebrohepatopathy Spectrum (C579990)
..Coenzyme Q10 Deficiency (C564403)
..Combined Oxidative Phosphorylation Deficiency 4 (C565690) L: 00098;
..Combined Oxidative Phosphorylation Deficiency 5 (C567126) L: 00099;
..Cowden-Like Syndrome (C567337)
..Cytochrome-c Oxidase Deficiency (D030401) 2 C:2 L: 00012;
..Deoxyguanosine Kinase Deficiency (C580039)
..ENCEPHALOPATHY DUE TO DEFECTIVE MITOCHONDRIAL AND PEROXISOMAL FISSION 1 (OMIM:614388) L: 00014;
..ENCEPHALOPATHY DUE TO DEFECTIVE MITOCHONDRIAL AND PEROXISOMAL FISSION 2 (OMIM:617086) L: 00525;
..Finnish lethal neonatal metabolic syndrome (C537934) L: 00104;
..Friedreich Ataxia (D005621) 6 C:1
..Hypermetabolism due to Defect in Mitochondria (C565498)
..Hypomyelination, Global Cerebral (C567847) L: 00107;
..Hypotonia-Cystinuria Syndrome (C564710) L: 00416;
..Kearns-Sayre Syndrome (D007625) 1 L: 00143;
..Leigh Disease (D007888) 12 C:3 L: 00015;
..Leukodystrophy, Hypomyelinating, 4 (C567390) L: 00421;
..Leukoencephalopathy with Brainstem and Spinal Cord Involvement and Lactate Elevation (C567009) L: 00418;
..LIPOYLTRANSFERASE 1 DEFICIENCY (OMIM:616299)
..Medium Chain 3-Ketoacyl-CoA Thiolase Deficiency (C566566)
..Mitochondrial complex I deficiency (C537475) L: 00011;
..Mitochondrial Complex II Deficiency (C565375) L: 00016;
..Mitochondrial Complex III Deficiency (C565128) L: 00018; 00019; 00020; 00021; 00022; 00507; 00508; 00528;
..MITOCHONDRIAL COMPLEX V (ATP SYNTHASE) DEFICIENCY, NUCLEAR TYPE 1 (OMIM:604273) L: 00023;
..MITOCHONDRIAL COMPLEX V (ATP SYNTHASE) DEFICIENCY, NUCLEAR TYPE 2 (OMIM:614052) L: 00024;
..MITOCHONDRIAL COMPLEX V (ATP SYNTHASE) DEFICIENCY, NUCLEAR TYPE 3 (OMIM:614053) L: 00025;
..MITOCHONDRIAL COMPLEX V (ATP SYNTHASE) DEFICIENCY, NUCLEAR TYPE 4 (OMIM:615228) L: 00010;
..MITOCHONDRIAL DNA DEPLETION SYNDROME 3 (HEPATOCEREBRAL TYPE) (OMIM:251880) L: 00031;
..MITOCHONDRIAL DNA DEPLETION SYNDROME 4A (ALPERS TYPE) (OMIM:203700) L: 00032;
..Mitochondrial DNA Depletion Syndrome, Myopathic Form (C563698)
..Mitochondrial Myopathies (D017240) 33 C:22 L: 00400;
..Mitochondrial Phosphate Carrier Deficiency (C563665) L: 00040;
..MITOCHONDRIAL PYRUVATE CARRIER DEFICIENCY (OMIM:614741) L: 00041;
..Multiple Acyl Coenzyme A Dehydrogenase Deficiency (D054069) 1 L: 00439;
..Multiple Mitochondrial Dysfunctions Syndrome (C565304) L: 00013; 00043; 00530;
..Myopathy with Giant Abnormal Mitochondria (C564971)
..Myopathy, Cataract, Hypogonadism Syndrome (C563578)
..Navajo neurohepatopathy (C538344) 1 C:1 L: 00035;
..Noninsulin-dependent diabetes mellitus with deafness (C536246)
..Ophthalmoplegic Neuromuscular Disorder with Abnormal Mitochondria (C564925)
..Optic Atrophy, Autosomal Dominant (D029241) L: 00073;
..Optic Atrophy, Hereditary, Leber (D029242) 1 L: 00072; 00492;
..Parkinson Disease, Mitochondrial (C564015) L: 00170;
..Phosphoenolpyruvate Carboxykinase Deficiency, Mitochondrial (C564890)
..Progressive External Ophthalmoplegia With Hypogonadism (C563576)
..Progressive External Ophthalmoplegia with Mitochondrial DNA Deletions, Autosomal Dominant, 1 (C563575) L: 00117;
..Progressive External Ophthalmoplegia With Mitochondrial Dna Deletions, Autosomal Dominant, 5 (C567768) L: 00049;
..Proximal Myopathy with Focal Depletion of Mitochondria (C563453)
..Pyruvate Carboxylase Deficiency Disease (D015324) 1 L: 00398;
..Pyruvate Dehydrogenase Complex Deficiency Disease (D015325) 4 C:3 L: 00442;
..Sarcosinemia (C537236)
..Spinocerebellar Ataxia with Epilepsy (C564395)
..Succinate-Coa Ligase Deficiency (C580473)
..VDAC Deficiency (C565767)
..VLCAD deficiency (C536353) L: 00436;
..Wolfram Syndrome 2 (C565733) L: 00490;
Human Disease MESH is developed by UMLS. Further data from MedGen, OMIM,ClinVar, CTD

Term ID:

8083

Name:

Mitochondrial Complex II Deficiency

Definition:

Alternative IDs:

DO:DOID:0060537|OMIM:252011

ParentIDs:

MESH:D008661|MESH:D028361

TreeNumbers:

C16.320.565/C565375 |C18.452.648/C565375 |C18.452.660/C565375

Synonyms:

Succinate CoQ Reductase Deficiency

Slim Mappings:

Genetic disease (inborn)|Metabolic disease

Reference:

MedGen: C565375
MeSH: C565375
OMIM: 252011;
MSeqDR : 00016;
Genes: SDHA; SDHAF1;

Phenotypes

1	HP:0000007	Autosomal recessive inheritance
2	HP:0003593	Infantile onset
3	HP:0008316	Abnormal mitochondria in muscle tissue
4	HP:0001251	Ataxia
5	HP:0003487	Babinski sign
6	HP:0100543	Cognitive impairment NAMDC: Cognitive delay
7	HP:0008314	Decreased activity of mitochondrial complex II
8	HP:0002376	Developmental regression
9	HP:0001644	Dilated cardiomyopathy NAMDC: Dilated cardiomyopathy
10	HP:0001332	Dystonia NAMDC: Dystonia
11	HP:0003546	Exercise intolerance NAMDC: Exercise intolerance
12	HP:0001371	Flexion contracture
13	HP:0001347	Hyperreflexia NAMDC: Hyperreactive reflexes (incl. Babinski sign, Hoffman sign)
14	HP:0001639	Hypertrophic cardiomyopathy NAMDC: Hypertrophic cardomyopathy
15	HP:0012240	Increased intramyocellular lipid droplets
16	HP:0002151	Increased serum lactate
17	HP:0030682	Left ventricular noncompaction
18	HP:0001324	Muscle weakness NAMDC: Muscle weakness: diffuse
19	HP:0001336	Myoclonus NAMDC: Myoclonus
20	HP:0001319	Neonatal hypotonia NAMDC: Floppy baby
21	HP:0000639	Nystagmus
22	HP:0000602	Ophthalmoplegia
23	HP:0000648	Optic atrophy
24	HP:0003812	Phenotypic variability
25	HP:0000580	Pigmentary retinopathy NAMDC: Pigmentary retinopathy
26	HP:0006980	Progressive leukoencephalopathy
27	HP:0000508	Ptosis NAMDC: Ptosis
28	HP:0003200	Ragged-red muscle fibers
29	HP:0001250	Seizures NAMDC: Seizures
30	HP:0004322	Short stature NAMDC: Short stature (patient��s height is below the 3rd percentile)
31	HP:0001257	Spasticity NAMDC: Spasticity
32	HP:0004897	Stress/infection-induced lactic acidosis
33	HP:0000505	Visual impairment

Disease Causing ClinVar Variants

Variation_Name	GeneID	GeneSymbol	ClinicalSignificance	dbSNP	RCVaccession	TestedInGTR	PhenotypeIDs	Chromosome	Start	Stop	HGVS_g	OtherIDs	Disease_ClinVar
NM_004168.3(SDHA):c.-115T>C	6389	SDHA	Likely benign	2303741	RCV000313041\|RCV000338764\|RCV000400671;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506\|Human Phenotype Ontology:HP:0002666,MONDO:MONDO:0008233,MedGen:C0031511,OMIM:171300, Orphanet:29072	5	218356	218356	NC_000005.9:g.218356T>C	ClinGen:CA10624324	C0023264 256000 Leigh syndrome;
NM_004168.3(SDHA):c.-84dup	6389	SDHA	Likely benign	35805262	RCV000307350\|RCV000370159\|RCV000399941;	N	MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506\|Human Phenotype Ontology:HP:0002666,MONDO:MONDO:0008233,MedGen:C0031511,OMIM:171300, Orphanet:29072\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	218381	218382	NC_000005.9:g.218387dup	ClinGen:CA10621606	C0023264 256000 Leigh syndrome;
NM_004168.3(SDHA):c.-63G>A	6389	SDHA	Uncertain significance	886060513	RCV000272151\|RCV000329506\|RCV000364389;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506\|Human Phenotype Ontology:HP:0002666,MONDO:MONDO:0008233,MedGen:C0031511,OMIM:171300, Orphanet:29072	5	218408	218408	NC_000005.9:g.218408G>A	ClinGen:CA10621607	C0023264 256000 Leigh syndrome;
NM_004168.4(SDHA):c.-7A>C	6389	SDHA	Conflicting interpretations of pathogenicity	751633537	RCV000411889\|RCV000425129\|RCV000649475\|RCV000756629\|RCV001151933\|RCV001151931\|RCV001151932\|RCV002255377;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MedGen:CN169374\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MedGen:C3661900\|MONDO:MONDO:0009723,MedGen:C00232	5	218464	218464	NC_000005.9:g.218464A>C	ClinGen:CA3172666	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.-4A>G	6389	SDHA	Benign/Likely benign	377134185	RCV000251091\|RCV000266213\|RCV000358590\|RCV000323529\|RCV000572973;	N	MedGen:CN169374\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506\|MONDO:MONDO:0017366,MedGen:C1708353, Orphanet:29072\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:14016	5	218467	218467	NC_000005.9:g.218467A>G	ClinGen:CA3172670	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.-2A>T	6389	SDHA	Conflicting interpretations of pathogenicity	763680697	RCV000564955\|RCV001153196\|RCV001151934\|RCV001153197\|RCV003139877;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0017366,MedGen:C1708353, Orphanet:29072\|MedGen:C366190	5	218469	218469	5:g.218469A>T	ClinGen:CA3172671	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.-1C>T	6389	SDHA	Conflicting interpretations of pathogenicity	560932680	RCV000279041\|RCV000317717\|RCV000380480\|RCV001013984\|RCV003137969;	N	MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0017366,MedGen:C1708353, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C366190	5	218470	218470	NC_000005.9:g.218470C>T	ClinGen:CA3172673	C0023264 256000 Leigh syndrome;
NM_004168.4(SDHA):c.1A>C (p.Met1Leu)	6389	SDHA	Pathogenic	1061517	RCV000009283\|RCV001233940\|RCV002415407\|RCV003450622\|RCV003234897;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|M	5	218471	218471	5:g.218471A>C	ClinGen:CA119881,OMIM:600857.0003	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1A>G (p.Met1Val)	6389	SDHA	Pathogenic/Likely pathogenic	1061517	RCV000230468\|RCV000567727\|RCV000579224\|RCV000656497;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165	5	218471	218471	NC_000005.9:g.218471A>G	ClinGen:CA3172674	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1A>T (p.Met1Leu)	6389	SDHA	Pathogenic/Likely pathogenic	1061517	RCV000410820\|RCV001041479\|RCV002418229\|RCV003237835;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|	5	218471	218471	NC_000005.9:g.218471A>T	ClinGen:CA16042099	C3279992 614165 Paragangliomas 5;
NM_004168.4(SDHA):c.1del (p.Met1fs)	6389	SDHA	Pathogenic	1085307796	RCV000490141\|RCV001046092;	N	MedGen:CN517202\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	218471	218471	NC_000005.9:g.218471del	ClinGen:CA645293865
NM_004168.4(SDHA):c.7_24dup (p.Ser8_Arg9insGlyValArgGlyLeuSer)	6389	SDHA	Uncertain significance	-1	RCV003040638;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	218471	218472	NC_000005.9:g.218477_218494dup	-
NM_004168.4(SDHA):c.2T>C (p.Met1Thr)	6389	SDHA	Pathogenic/Likely pathogenic	750380279	RCV000462474\|RCV000662887\|RCV001017951;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	218472	218472	NC_000005.9:g.218472T>C	ClinGen:CA16611812	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.2T>G (p.Met1Arg)	6389	SDHA	Pathogenic/Likely pathogenic	750380279	RCV000478025\|RCV000649438\|RCV001257552\|RCV002438178\|RCV002506172;	N	MedGen:C3661900\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|Human Phenotype Ontology:HP:0002859,MONDO:MONDO:0005212,MeSH:D012208,MedGen:C0035412, Orphanet:780\|MONDO:MONDO:00	5	218472	218472	5:g.218472T>G	ClinGen:CA16618195	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.2T>A (p.Met1Lys)	6389	SDHA	Pathogenic	750380279	RCV000706101\|RCV002440542\|RCV003148837;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	218472	218472	5:g.218472T>A	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.3G>C (p.Met1Ile)	6389	SDHA	Pathogenic	2126522051	RCV001962939;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	218473	218473	218473	-
NM_004168.4(SDHA):c.3G>T (p.Met1Ile)	6389	SDHA	Pathogenic	2126522051	RCV001930243\|RCV003167128;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	218473	218473	218473	-
NM_004168.4(SDHA):c.4T>C (p.Ser2Pro)	6389	SDHA	Uncertain significance	758327622	RCV001954520;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	218474	218474	218474	-
NM_004168.4(SDHA):c.4T>G (p.Ser2Ala)	6389	SDHA	Uncertain significance	758327622	RCV001902064;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	218474	218474	218474	-
NM_004168.4(SDHA):c.5dup (p.Val4fs)	6389	SDHA	Pathogenic	-1	RCV002357983\|RCV003098098;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	218474	218475	218474	-
NM_004168.4(SDHA):c.5C>T (p.Ser2Leu)	6389	SDHA	Conflicting interpretations of pathogenicity	780064103	RCV000473246\|RCV000569083\|RCV001153199\|RCV001153200\|RCV001153198\|RCV003225073;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506\|MO	5	218475	218475	NC_000005.9:g.218475C>T	ClinGen:CA3172677	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.5C>A (p.Ser2Ter)	6389	SDHA	Pathogenic	780064103	RCV000797937;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	218475	218475	5:g.218475C>A	-
NM_004168.4(SDHA):c.6G>A (p.Ser2=)	6389	SDHA	Likely benign	751383247	RCV000976847\|RCV002363492;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	218476	218476	5:g.218476G>A	-
NM_004168.4(SDHA):c.6G>C (p.Ser2=)	6389	SDHA	Likely benign	751383247	RCV001025905\|RCV001446069;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	218476	218476	5:g.218476G>C	-
NM_004168.4(SDHA):c.6G>T (p.Ser2=)	6389	SDHA	Likely benign	751383247	RCV001025906\|RCV002069027;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	218476	218476	5:g.218476G>T	-
NM_004168.4(SDHA):c.7G>C (p.Gly3Arg)	6389	SDHA	Uncertain significance	756415935	RCV001064968\|RCV002418534;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	218477	218477	5:g.218477G>C	-
NM_004168.4(SDHA):c.7G>T (p.Gly3Trp)	6389	SDHA	Uncertain significance	756415935	RCV001350608;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	218477	218477	218477	-
NM_004168.4(SDHA):c.8G>C (p.Gly3Ala)	6389	SDHA	Uncertain significance	1398198098	RCV000703530\|RCV002369948;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	218478	218478	5:g.218478G>C	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.9G>T (p.Gly3=)	6389	SDHA	Likely benign	1252447154	RCV000570635\|RCV000873441;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	218479	218479	5:g.218479G>T	ClinGen:CA442689528	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.9G>C (p.Gly3=)	6389	SDHA	Likely benign	1252447154	RCV001462291\|RCV003160874;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	218479	218479	218479	-
NM_004168.4(SDHA):c.9G>A (p.Gly3=)	6389	SDHA	Likely benign	-1	RCV002383152\|RCV003094918;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	218479	218479		-
NM_004168.4(SDHA):c.10G>T (p.Val4Phe)	6389	SDHA	Uncertain significance	778069799	RCV001017300\|RCV001873289;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	218480	218480	5:g.218480G>T	-
NM_004168.4(SDHA):c.10G>A (p.Val4Ile)	6389	SDHA	Uncertain significance	778069799	RCV001243739\|RCV002430036\|RCV003473824;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	218480	218480	5:g.218480G>A	-
NM_004168.4(SDHA):c.12C>T (p.Val4=)	6389	SDHA	Likely benign	749406988	RCV000468506\|RCV002383905;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	218482	218482	NC_000005.9:g.218482C>T	ClinGen:CA3172681	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.13C>T (p.Arg5Trp)	6389	SDHA	Uncertain significance	770866830	RCV000473159\|RCV001011369\|RCV002506135\|RCV003226934;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072;	5	218483	218483	NC_000005.9:g.218483C>T	ClinGen:CA16612037	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.13C>G (p.Arg5Gly)	6389	SDHA	Uncertain significance	770866830	RCV001241674\|RCV002393625;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	218483	218483	5:g.218483C>G	-
NM_004168.4(SDHA):c.13C>A (p.Arg5=)	6389	SDHA	Likely benign	770866830	RCV001464905\|RCV002396097;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	218483	218483	218483	-
NM_004168.4(SDHA):c.14G>A (p.Arg5Gln)	6389	SDHA	Uncertain significance	779027774	RCV000691271\|RCV002388232\|RCV002499232;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072;	5	218484	218484	NC_000005.9:g.218484G>A	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.15G>A (p.Arg5=)	6389	SDHA	Likely benign	1260744894	RCV002190206;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	218485	218485	218485	-
NM_004168.4(SDHA):c.16G>A (p.Gly6Ser)	6389	SDHA	Uncertain significance	1352756438	RCV001220326;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	218486	218486	5:g.218486G>A	-
NM_004168.4(SDHA):c.16G>C (p.Gly6Arg)	6389	SDHA	Conflicting interpretations of pathogenicity	1352756438	RCV001893473\|RCV002397867;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	218486	218486	218486	-
NM_004168.4(SDHA):c.17G>A (p.Gly6Asp)	6389	SDHA	Conflicting interpretations of pathogenicity	187964306	RCV000216190\|RCV000224380\|RCV000282383\|RCV000374489\|RCV000411625\|RCV000349064\|RCV000573807\|RCV001080211;	N	MedGen:CN169374\|MedGen:C3661900\|MONDO:MONDO:0017366,MedGen:C1708353, Orphanet:29072\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:2560	5	218487	218487	NC_000005.9:g.218487G>A	ClinGen:CA358571	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.17G>C (p.Gly6Ala)	6389	SDHA	Conflicting interpretations of pathogenicity	187964306	RCV001068961\|RCV002411605;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	218487	218487	5:g.218487G>C	-
NM_004168.4(SDHA):c.17G>T (p.Gly6Val)	6389	SDHA	Uncertain significance	187964306	RCV001053064\|RCV002409443;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	218487	218487	5:g.218487G>T	-
NM_004168.4(SDHA):c.17_18insA (p.Leu7fs)	6389	SDHA	Pathogenic	-1	RCV002881583;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	218487	218488	NC_000005.9:g.218487_218488insA	-
NM_004168.4(SDHA):c.18C>A (p.Gly6=)	6389	SDHA	Likely benign	775847689	RCV000556103\|RCV002413608;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	218488	218488	NC_000005.9:g.218488C>A	ClinGen:CA442689535	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.18C>T (p.Gly6=)	6389	SDHA	Likely benign	775847689	RCV000701813\|RCV001013607;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	218488	218488	NC_000005.9:g.218488C>T	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.19C>T (p.Leu7=)	6389	SDHA	Likely benign	760964443	RCV000943379\|RCV001013999;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	218489	218489	5:g.218489C>T	-
NM_004168.4(SDHA):c.19C>G (p.Leu7Val)	6389	SDHA	Uncertain significance	760964443	RCV001039293;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	218489	218489	5:g.218489C>G	-
NM_004168.4(SDHA):c.20T>C (p.Leu7Pro)	6389	SDHA	Uncertain significance	1734500083	RCV001216867\|RCV002418744;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	218490	218490	5:g.218490T>C	-
NM_004168.4(SDHA):c.22T>C (p.Ser8Pro)	6389	SDHA	Uncertain significance	768328967	RCV001041680;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	218492	218492	5:g.218492T>C	-
NM_004168.4(SDHA):c.23C>G (p.Ser8Trp)	6389	SDHA	Uncertain significance	878854631	RCV000228753\|RCV001762532\|RCV002444900\|RCV003475075;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642	5	218493	218493	5:g.218493C>G	ClinGen:CA10582417	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.23C>T (p.Ser8Leu)	6389	SDHA	Uncertain significance	878854631	RCV001970237\|RCV003339859;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	218493	218493	218493	-
NM_004168.4(SDHA):c.23C>A (p.Ser8Ter)	6389	SDHA	Pathogenic	878854631	RCV001993135\|RCV003303493;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	218493	218493	218493	-
NM_004168.4(SDHA):c.24G>C (p.Ser8=)	6389	SDHA	Likely benign	1060505007	RCV000573332\|RCV001429572;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	218494	218494	NC_000005.9:g.218494G>C	ClinGen:CA16611815	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.25C>G (p.Arg9Gly)	6389	SDHA	Uncertain significance	776218604	RCV000649459\|RCV003303065;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	218495	218495	NC_000005.9:g.218495C>G	ClinGen:CA359007301	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.25C>T (p.Arg9Trp)	6389	SDHA	Uncertain significance	776218604	RCV001225154;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	218495	218495	5:g.218495C>T	-
NM_004168.4(SDHA):c.26G>A (p.Arg9Gln)	6389	SDHA	Uncertain significance	761508577	RCV000691725;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	218496	218496	NC_000005.9:g.218496G>A	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.26G>T (p.Arg9Leu)	6389	SDHA	Uncertain significance	761508577	RCV001041332;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	218496	218496	5:g.218496G>T	-
NM_004168.4(SDHA):c.27G>A (p.Arg9=)	6389	SDHA	Likely benign	2126522501	RCV002112961\|RCV002434494;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	218497	218497	218497	-
NM_004168.4(SDHA):c.28del (p.Leu10fs)	6389	SDHA	Pathogenic	1579369841	RCV000810724;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	218498	218498	5:g.218498_218498del	-
NM_004168.4(SDHA):c.28C>T (p.Leu10=)	6389	SDHA	Likely benign	879099314	RCV001452779;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	218498	218498	218498	-
NM_004168.4(SDHA):c.29T>C (p.Leu10Pro)	6389	SDHA	Uncertain significance	2126522536	RCV001901686;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	218499	218499	218499	-
NM_004168.4(SDHA):c.32T>A (p.Leu11Gln)	6389	SDHA	Uncertain significance	1139422	RCV001054132;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	218502	218502	5:g.218502T>A	-
NM_004168.4(SDHA):c.33G>T (p.Leu11=)	6389	SDHA	Likely benign	1139423	RCV002169794\|RCV002454347;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	218503	218503	218503	-
NM_004168.4(SDHA):c.34A>G (p.Ser12Gly)	6389	SDHA	Uncertain significance	1734501874	RCV001213050\|RCV002451462;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	218504	218504	5:g.218504A>G	-
NM_004168.4(SDHA):c.36C>A (p.Ser12Arg)	6389	SDHA	Uncertain significance	1734502045	RCV001036917;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	218506	218506	5:g.218506C>A	-
NM_004168.4(SDHA):c.39T>C (p.Ala13=)	6389	SDHA	Likely benign	2126522607	RCV001417596\|RCV003298700;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	218509	218509	218509	-
NM_004168.4(SDHA):c.40C>A (p.Arg14=)	6389	SDHA	Likely benign	1192077362	RCV000549482\|RCV001021865;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	218510	218510	NC_000005.9:g.218510C>A	ClinGen:CA442689557	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.46_52dup (p.Leu18fs)	6389	SDHA	Pathogenic/Likely pathogenic	1560980939	RCV000696009\|RCV003128647;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MedGen:CN517202	5	218510	218511	5:g.218510_218511insGGCGCCT	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.40C>T (p.Arg14Trp)	6389	SDHA	Uncertain significance	1192077362	RCV001221686\|RCV002322073\|RCV002484205;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; M	5	218510	218510	5:g.218510C>T	-
NM_004168.4(SDHA):c.40C>G (p.Arg14Gly)	6389	SDHA	Uncertain significance	1192077362	RCV001248215\|RCV002322164;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	218510	218510	5:g.218510C>G	-
NM_004168.4(SDHA):c.44G>C (p.Arg15Pro)	6389	SDHA	Uncertain significance	1060503707	RCV000470530\|RCV002255398;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	218514	218514	NC_000005.9:g.218514G>C	ClinGen:CA16611820	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.44G>T (p.Arg15Leu)	6389	SDHA	Uncertain significance	-1	RCV002305344;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	218514	218514	218514	-
NM_004168.4(SDHA):c.45C>T (p.Arg15=)	6389	SDHA	Likely benign	1060505002	RCV001478123\|RCV002341121;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	218515	218515	NC_000005.9:g.218515C>T	ClinGen:CA16612038	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.46C>T (p.Leu16=)	6389	SDHA	Likely benign	1579369903	RCV000921727;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	218516	218516	5:g.218516C>T	-
NM_004168.4(SDHA):c.48G>A (p.Leu16=)	6389	SDHA	Likely benign	2126522691	RCV002040196;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	218518	218518	218518	-
NM_004168.4(SDHA):c.48G>C (p.Leu16=)	6389	SDHA	Likely benign	2126522691	RCV002139955\|RCV002337357;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	218518	218518	218518	-
NM_004168.4(SDHA):c.49G>A (p.Ala17Thr)	6389	SDHA	Uncertain significance	-1	RCV002592748;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	218519	218519	NC_000005.9:g.218519G>A	-
NM_004168.4(SDHA):c.51G>A (p.Ala17=)	6389	SDHA	Likely benign	764698195	RCV001023712\|RCV001082535\|RCV002501254;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0031006,MedGen:C5543254,OMIM:619259; MONDO:MONDO:001	5	218521	218521	5:g.218521G>A	-
NM_004168.4(SDHA):c.52C>G (p.Leu18Val)	6389	SDHA	Uncertain significance	1553996372	RCV000572314\|RCV001204645;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	218522	218522	5:g.218522C>G	ClinGen:CA359007420	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.53T>A (p.Leu18Gln)	6389	SDHA	Uncertain significance	-1	RCV002615182;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	218523	218523	NC_000005.9:g.218523T>A	-
NM_004168.4(SDHA):c.54G>T (p.Leu18=)	6389	SDHA	Likely benign	-1	RCV003098967;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	218524	218524		-
NM_004168.4(SDHA):c.55G>A (p.Ala19Thr)	6389	SDHA	Conflicting interpretations of pathogenicity	1560980986	RCV000696776\|RCV002343493;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	218525	218525	5:g.218525G>A	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.56C>G (p.Ala19Gly)	6389	SDHA	Uncertain significance	2126522773	RCV002030327;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	218526	218526	218526	-
NM_004168.4(SDHA):c.57C>G (p.Ala19=)	6389	SDHA	Likely benign	749948037	RCV000842001\|RCV001024546\|RCV001084132;	N	MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	218527	218527	NC_000005.9:g.218527C>G	ClinGen:CA3172691	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.58A>G (p.Lys20Glu)	6389	SDHA	Uncertain significance	1734504263	RCV001298669\|RCV002357093;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	218528	218528	218528	-
NM_004168.4(SDHA):c.60G>T (p.Lys20Asn)	6389	SDHA	Uncertain significance	-1	RCV002943742\|RCV003308370;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	218530	218530	NC_000005.9:g.218530G>T	-
NM_004168.4(SDHA):c.60G>A (p.Lys20=)	6389	SDHA	Likely benign	-1	RCV002953545;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	218530	218530		-
NM_004168.4(SDHA):c.61G>A (p.Ala21Thr)	6389	SDHA	Uncertain significance	1553996375	RCV000556549;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	218531	218531	NC_000005.9:g.218531G>A	ClinGen:CA359007466	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.62C>T (p.Ala21Val)	6389	SDHA	Uncertain significance	2126522821	RCV001884830;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	218532	218532	218532	-
NM_004168.4(SDHA):c.62C>A (p.Ala21Glu)	6389	SDHA	Uncertain significance	2126522821	RCV002005224;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	218532	218532	218532	-
NM_004168.4(SDHA):c.63G>A (p.Ala21=)	6389	SDHA	Uncertain significance	587781942	RCV000130309\|RCV001304201;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	218533	218533	5:g.218533G>A	ClinGen:CA166153	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.63G>T (p.Ala21=)	6389	SDHA	Conflicting interpretations of pathogenicity	587781942	RCV001025228\|RCV001350507;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	218533	218533	5:g.218533G>T	-
NM_004168.4(SDHA):c.63+2del	6389	SDHA	Likely pathogenic	1579369969	RCV000810130\|RCV003166289;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	218535	218535	5:g.218535_218535del	-
NM_004168.4(SDHA):c.63+3del	6389	SDHA	Uncertain significance	1734505446	RCV001306930\|RCV003473853;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	218536	218536	218535	-
NM_004168.4(SDHA):c.63+4A>G	6389	SDHA	Uncertain significance	-1	RCV002937422;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	218537	218537	NC_000005.9:g.218537A>G	-
NM_004168.4(SDHA):c.63+7C>A	6389	SDHA	Uncertain significance	-1	RCV002811695;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	218540	218540	NC_000005.9:g.218540C>A	-
NM_004168.4(SDHA):c.63+8C>T	6389	SDHA	Likely benign	766358430	RCV000227123\|RCV003437021;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MedGen:C3661900	5	218541	218541	5:g.218541C>T	ClinGen:CA3172693	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.63+8C>A	6389	SDHA	Likely benign	766358430	RCV001416091;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	218541	218541	218541	-
NM_004168.4(SDHA):c.63+9G>A	6389	SDHA	Likely benign	751401688	RCV001487956;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	218542	218542	218542	-
NM_004168.4(SDHA):c.63+10T>C	6389	SDHA	Likely benign	2126522948	RCV002122156;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	218543	218543	218543	-
NM_004168.4(SDHA):c.63+10T>G	6389	SDHA	Likely benign	-1	RCV002710981;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	218543	218543	NC_000005.9:g.218543T>G	-
NM_004168.4(SDHA):c.63+13C>G	6389	SDHA	Likely benign	-1	RCV003073033;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	218546	218546	NC_000005.9:g.218546C>G	-
NM_004168.4(SDHA):c.63+14G>A	6389	SDHA	Likely benign	2126522961	RCV002088131;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	218547	218547	218547	-
NM_004168.4(SDHA):c.63+16G>C	6389	SDHA	Likely benign	1252759825	RCV002170220;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	218549	218549	218549	-
NM_004168.4(SDHA):c.63+18A>G	6389	SDHA	Likely benign	2126522991	RCV002213285;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	218551	218551	218551	-
NM_004168.4(SDHA):c.63+19C>A	6389	SDHA	Likely benign	1553996384	RCV000601436\|RCV002063079;	N	MedGen:CN169374\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	218552	218552	5:g.218552C>A	ClinGen:CA658796482	CN169374 not specified;
NM_004168.4(SDHA):c.63+20C>T	6389	SDHA	Likely benign	1734507324	RCV002199683;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	218553	218553	218553	-
NM_004168.4(SDHA):c.64-13_64-5del	6389	SDHA	Likely benign	1382759501	RCV002179809;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223575	223583	223574	-
NM_004168.4(SDHA):c.64-19G>A	6389	SDHA	Likely benign	1490248268	RCV002108542;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223578	223578	223578	-
NM_004168.4(SDHA):c.64-17G>A	6389	SDHA	Likely benign	-1	RCV003047990;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223580	223580	NC_000005.9:g.223580G>A	-
NM_004168.4(SDHA):c.64-15C>T	6389	SDHA	Likely benign	1388748464	RCV002217907;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223582	223582	223582	-
NM_004168.4(SDHA):c.64-13T>G	6389	SDHA	Likely benign	2126539312	RCV002195305;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	223584	223584	223584	-
NM_004168.4(SDHA):c.64-12C>T	6389	SDHA	Likely benign	769476810	RCV002215344;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	223585	223585	223585	-
NM_004168.4(SDHA):c.64-11T>C	6389	SDHA	Likely benign	2126539331	RCV001994610;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223586	223586	223586	-
NM_004168.4(SDHA):c.64-10G>A	6389	SDHA	Likely benign	1553997159	RCV000649470;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223587	223587	5:g.223587G>A	ClinGen:CA658796483	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.64-10G>C	6389	SDHA	Likely benign	1553997159	RCV001411778;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223587	223587	223587	-
NM_004168.4(SDHA):c.64-7T>C	6389	SDHA	Likely benign	1579379588	RCV001476978;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	223590	223590	5:g.223590T>C	-
NM_004168.4(SDHA):c.64-7T>G	6389	SDHA	Uncertain significance	1579379588	RCV001298651;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223590	223590	223590	-
NM_004168.4(SDHA):c.64-4C>T	6389	SDHA	Likely benign	-1	RCV002589961;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223593	223593	NC_000005.9:g.223593C>T	-
NM_004168.4(SDHA):c.64-3C>T	6389	SDHA	Uncertain significance	772607568	RCV000216659\|RCV000533456;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	223594	223594	5:g.223594C>T	ClinGen:CA3172711	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.64-2A>G	6389	SDHA	Pathogenic/Likely pathogenic	762456298	RCV001036409\|RCV001528244\|RCV002363550;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	223595	223595	5:g.223595A>G	-
NM_004168.4(SDHA):c.64-2A>C	6389	SDHA	Likely pathogenic	-1	RCV002628429;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223595	223595	NC_000005.9:g.223595A>C	-
NM_004168.4(SDHA):c.64T>C (p.Trp22Arg)	6389	SDHA	Uncertain significance	2126539375	RCV002033210;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223597	223597	223597	-
NM_004168.4(SDHA):c.65G>A (p.Trp22Ter)	6389	SDHA	Pathogenic	2126539382	RCV001946937;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223598	223598	223598	-
NM_004168.4(SDHA):c.70A>G (p.Thr24Ala)	6389	SDHA	Conflicting interpretations of pathogenicity	1579379632	RCV000816218\|RCV003166352;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	223603	223603	5:g.223603A>G	-
NM_004168.4(SDHA):c.71C>G (p.Thr24Arg)	6389	SDHA	Uncertain significance	-1	RCV003049788;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223604	223604	NC_000005.9:g.223604C>G	-
NM_004168.4(SDHA):c.72A>C (p.Thr24=)	6389	SDHA	Likely benign	2126539424	RCV001440236;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	223605	223605	223605	-
NM_004168.4(SDHA):c.72A>G (p.Thr24=)	6389	SDHA	Likely benign	2126539424	RCV001445168;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223605	223605	223605	-
NM_004168.4(SDHA):c.74T>C (p.Val25Ala)	6389	SDHA	Uncertain significance	2126539437	RCV001965794;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223607	223607	223607	-
NM_004168.4(SDHA):c.75G>A (p.Val25=)	6389	SDHA	Likely benign	774378936	RCV002178106\|RCV002391170;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	223608	223608	223608	-
NM_004168.4(SDHA):c.79C>G (p.Gln27Glu)	6389	SDHA	Uncertain significance	1734829878	RCV001039324;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	223612	223612	5:g.223612C>G	-
NM_004168.4(SDHA):c.79C>T (p.Gln27Ter)	6389	SDHA	Pathogenic	1734829878	RCV001385763\|RCV002420861;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	223612	223612	223612	-
NM_004168.4(SDHA):c.81A>G (p.Gln27=)	6389	SDHA	Likely benign	759523671	RCV002129162\|RCV002427696;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	223614	223614	223614	-
NM_004168.4(SDHA):c.83dup (p.Gly29fs)	6389	SDHA	Pathogenic	1734830402	RCV001037616;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	223615	223616	5:g.223615_223616insC	-
NM_004168.4(SDHA):c.83C>T (p.Thr28Ile)	6389	SDHA	Uncertain significance	1171584124	RCV001935291;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	223616	223616	223616	-
NM_004168.4(SDHA):c.84A>G (p.Thr28=)	6389	SDHA	Likely benign	1553997162	RCV000603424\|RCV001494315\|RCV002448860;	N	MedGen:CN169374\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	223617	223617	5:g.223617A>G	ClinGen:CA442689802	CN169374 not specified;
NM_004168.4(SDHA):c.86G>A (p.Gly29Glu)	6389	SDHA	Uncertain significance	1436200566	RCV000542539\|RCV001018205\|RCV001755880;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	5	223619	223619	NC_000005.9:g.223619G>A	ClinGen:CA359008107	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.88A>G (p.Thr30Ala)	6389	SDHA	Uncertain significance	2126539529	RCV002040499;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223621	223621	223621	-
NM_004168.4(SDHA):c.89C>T (p.Thr30Ile)	6389	SDHA	Uncertain significance	1560985157	RCV000699826\|RCV002369914\|RCV003472232;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	223622	223622	5:g.223622C>T	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.90C>G (p.Thr30=)	6389	SDHA	Likely benign	2126539545	RCV001489023;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223623	223623	223623	-
NM_004168.4(SDHA):c.92G>A (p.Arg31Gln)	6389	SDHA	Conflicting interpretations of pathogenicity	752532780	RCV000225880\|RCV000410721\|RCV000571153\|RCV001589187\|RCV002478861\|RCV003475078;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|	5	223625	223625	NC_000005.9:g.223625G>A	ClinGen:CA3172716	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.94G>C (p.Gly32Arg)	6389	SDHA	Uncertain significance	1734831542	RCV001318592;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223627	223627	223627	-
NM_004168.4(SDHA):c.96T>C (p.Gly32=)	6389	SDHA	Likely benign	2126539605	RCV002167795\|RCV002372846;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	223629	223629	223629	-
NM_004168.4(SDHA):c.98T>C (p.Phe33Ser)	6389	SDHA	Uncertain significance	1734831975	RCV001218025;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223631	223631	5:g.223631T>C	-
NM_004168.4(SDHA):c.99_108del (p.Phe33fs)	6389	SDHA	Pathogenic	1734832099	RCV001223903;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223631	223640	5:g.223631_223640del	-
NM_004168.4(SDHA):c.101A>G (p.His34Arg)	6389	SDHA	Uncertain significance	757478250	RCV001009716\|RCV001226605;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223634	223634	5:g.223634A>G	-
NM_004168.4(SDHA):c.102C>T (p.His34=)	6389	SDHA	Likely benign	2126539644	RCV002117682\|RCV002382369;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	223635	223635	223635	-
NM_004168.4(SDHA):c.106A>G (p.Thr36Ala)	6389	SDHA	Uncertain significance	750500173	RCV000218672\|RCV000559108\|RCV002509312\|RCV003475003;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MedGen:C3661900\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642	5	223639	223639	5:g.223639A>G	ClinGen:CA3172719	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.106A>T (p.Thr36Ser)	6389	SDHA	Uncertain significance	750500173	RCV000688361\|RCV001017190\|RCV003472191;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	223639	223639	5:g.223639A>T	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.107C>T (p.Thr36Ile)	6389	SDHA	Uncertain significance	1440814662	RCV000563141\|RCV001242428\|RCV003471906;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	223640	223640	5:g.223640C>T	ClinGen:CA359008161	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.108T>C (p.Thr36=)	6389	SDHA	Likely benign	1301747916	RCV001399952;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223641	223641	223641	-
NM_004168.4(SDHA):c.109G>A (p.Val37Ile)	6389	SDHA	Conflicting interpretations of pathogenicity	758426529	RCV000229719\|RCV000574162\|RCV000662820\|RCV003441813;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|	5	223642	223642	5:g.223642G>A	ClinGen:CA3172720	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.112G>C (p.Asp38His)	6389	SDHA	Uncertain significance	1553997174	RCV000649394;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223645	223645	NC_000005.9:g.223645G>C	ClinGen:CA359008177	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.112G>A (p.Asp38Asn)	6389	SDHA	Uncertain significance	1553997174	RCV001929371;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	223645	223645	223645	-
NM_004168.4(SDHA):c.113A>T (p.Asp38Val)	6389	SDHA	Benign/Likely benign	34635677	RCV000210535\|RCV000295347\|RCV000245657\|RCV000352522\|RCV000387287\|RCV000567706\|RCV000757746\|RCV001262690\|RCV003316169;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0017366,MedGen:C1708353, Orphanet:29072\|MedGen:CN169374\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506\|	5	223646	223646	NC_000005.9:g.223646A>T	UniProtKB:P31040#VAR_049215,ClinGen:CA358585	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.114T>C (p.Asp38=)	6389	SDHA	Likely benign	-1	RCV002452677\|RCV003094291;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223647	223647		-
NM_004168.4(SDHA):c.119A>G (p.Asn40Ser)	6389	SDHA	Uncertain significance	1734833856	RCV001222957;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223652	223652	5:g.223652A>G	-
NM_004168.4(SDHA):c.120C>G (p.Asn40Lys)	6389	SDHA	Uncertain significance	1579379803	RCV001010348\|RCV001862766;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223653	223653	5:g.223653C>G	-
NM_004168.4(SDHA):c.120C>T (p.Asn40=)	6389	SDHA	Likely benign	1579379803	RCV001010349\|RCV001492667;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223653	223653	5:g.223653C>T	-
NM_004168.4(SDHA):c.120C>A (p.Asn40Lys)	6389	SDHA	Uncertain significance	1579379803	RCV001234262;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223653	223653	5:g.223653C>A	-
NM_004168.4(SDHA):c.121A>C (p.Lys41Gln)	6389	SDHA	Uncertain significance	1061520	RCV001212961\|RCV002365956;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	223654	223654	5:g.223654A>C	-
NM_004168.4(SDHA):c.124_125dup (p.Ala43fs)	6389	SDHA	Pathogenic	1385076821	RCV001389282;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223654	223655	223654	-
NM_004168.4(SDHA):c.123G>A (p.Lys41=)	6389	SDHA	Likely benign	1553997185	RCV000552529\|RCV001010515;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	223656	223656	NC_000005.9:g.223656G>A	ClinGen:CA442689950	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.125G>A (p.Arg42Lys)	6389	SDHA	Uncertain significance	747557411	RCV000649445\|RCV002424509;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	223658	223658	NC_000005.9:g.223658G>A	ClinGen:CA3172721	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.126G>A (p.Arg42=)	6389	SDHA	Likely benign	2126539845	RCV001395474\|RCV003169961;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	223659	223659	223659	-
NM_004168.4(SDHA):c.127G>A (p.Ala43Thr)	6389	SDHA	Uncertain significance	1579379865	RCV000800127\|RCV001010719;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	223660	223660	5:g.223660G>A	-
NM_004168.4(SDHA):c.131C>A (p.Ser44Tyr)	6389	SDHA	Uncertain significance	1734835164	RCV001224422;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223664	223664	5:g.223664C>A	-
NM_004168.4(SDHA):c.131C>T (p.Ser44Phe)	6389	SDHA	Uncertain significance	1734835164	RCV001212267;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223664	223664	5:g.223664C>T	-
NM_004168.4(SDHA):c.131C>G (p.Ser44Cys)	6389	SDHA	Uncertain significance	-1	RCV003021309;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223664	223664	NC_000005.9:g.223664C>G	-
NM_004168.4(SDHA):c.132T>A (p.Ser44=)	6389	SDHA	Likely benign	-1	RCV002755073;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223665	223665		-
NM_004168.4(SDHA):c.133G>A (p.Ala45Thr)	6389	SDHA	Conflicting interpretations of pathogenicity	140736646	RCV000210508\|RCV000308179\|RCV000347454\|RCV000401643\|RCV000410936\|RCV000572294\|RCV000678682\|RCV001355540\|RCV003330583;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506\|MONDO:MONDO:0017366,MedGen:C1708353, Orphanet:29072\|MONDO:MONDO:0100	5	223666	223666	NC_000005.9:g.223666G>A	ClinGen:CA358573	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.133G>C (p.Ala45Pro)	6389	SDHA	Uncertain significance	140736646	RCV001971036\|RCV002386843;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	223666	223666	223666	-
NM_004168.4(SDHA):c.134C>T (p.Ala45Val)	6389	SDHA	Uncertain significance	1553997190	RCV000571515\|RCV000807154;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223667	223667	NC_000005.9:g.223667C>T	ClinGen:CA359008269	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.136A>G (p.Lys46Glu)	6389	SDHA	Conflicting interpretations of pathogenicity	144599870	RCV000210526\|RCV000250106\|RCV000410409\|RCV000569199\|RCV001705183;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MedGen:CN169374\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672,	5	223669	223669	NC_000005.9:g.223669A>G	ClinGen:CA358581	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.138A>G (p.Lys46=)	6389	SDHA	Likely benign	-1	RCV003035175;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223671	223671		-
NM_004168.4(SDHA):c.141T>C (p.Val47=)	6389	SDHA	Likely benign	748490907	RCV001499538;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223674	223674	223674	-
NM_004168.4(SDHA):c.141T>G (p.Val47=)	6389	SDHA	Likely benign	748490907	RCV002159256;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223674	223674	223674	-
NM_004168.4(SDHA):c.142T>A (p.Ser48Thr)	6389	SDHA	Uncertain significance	-1	RCV003046386;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223675	223675	NC_000005.9:g.223675T>A	-
NM_004168.4(SDHA):c.144A>G (p.Ser48=)	6389	SDHA	Likely benign	-1	RCV003018461;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223677	223677		-
NM_004168.4(SDHA):c.145G>C (p.Asp49His)	6389	SDHA	Uncertain significance	1734836072	RCV001043194\|RCV003236859;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MedGen:C3661900	5	223678	223678	5:g.223678G>C	-
NM_004168.4(SDHA):c.146A>G (p.Asp49Gly)	6389	SDHA	Conflicting interpretations of pathogenicity	80207011	RCV000130407\|RCV000228248\|RCV000410621\|RCV001704054\|RCV001818312;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|	5	223679	223679	5:g.223679A>G	ClinGen:CA166372	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.147T>C (p.Asp49=)	6389	SDHA	Likely benign	2126539950	RCV001425772;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223680	223680	223680	-
NM_004168.4(SDHA):c.148T>G (p.Ser50Ala)	6389	SDHA	Uncertain significance	1560985310	RCV000688888;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223681	223681	NC_000005.9:g.223681T>G	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.149C>A (p.Ser50Tyr)	6389	SDHA	Uncertain significance	369321221	RCV001011909\|RCV001050816;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223682	223682	5:g.223682C>A	-
NM_004168.4(SDHA):c.149C>T (p.Ser50Phe)	6389	SDHA	Uncertain significance	369321221	RCV001011911\|RCV001234880;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223682	223682	5:g.223682C>T	-
NM_004168.4(SDHA):c.149C>G (p.Ser50Cys)	6389	SDHA	Uncertain significance	369321221	RCV001373831;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223682	223682	223682	-
NM_004168.4(SDHA):c.150C>T (p.Ser50=)	6389	SDHA	Conflicting interpretations of pathogenicity	140264486	RCV000531485\|RCV001011952\|RCV003431099;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	5	223683	223683	NC_000005.9:g.223683C>T	ClinGen:CA3172724	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.150_150+1delinsTA	6389	SDHA	Likely pathogenic	2126539987	RCV001379923;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223683	223684	223683	-
NM_004168.4(SDHA):c.150+1G>A	6389	SDHA	Conflicting interpretations of pathogenicity	1057523165	RCV000438780\|RCV000471142\|RCV000568947\|RCV003476016;	N	MedGen:C3661900\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642	5	223684	223684	5:g.223684G>A	ClinGen:CA16604887	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.150+2dup	6389	SDHA	Uncertain significance	1560985349	RCV000689582;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223684	223685	NC_000005.9:g.223685dup	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.150+1G>C	6389	SDHA	Conflicting interpretations of pathogenicity	1057523165	RCV001378129\|RCV003169937;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	223684	223684	223684	-
NM_004168.4(SDHA):c.150+4A>G	6389	SDHA	Uncertain significance	1734837029	RCV001306330\|RCV003166740;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	223687	223687	223687	-
NM_004168.4(SDHA):c.150+5G>T	6389	SDHA	Uncertain significance	770610694	RCV000704406\|RCV003165904;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	223688	223688	NC_000005.9:g.223688G>T	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.150+6T>G	6389	SDHA	Uncertain significance	1060503699	RCV000477184;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	223689	223689	NC_000005.9:g.223689T>G	ClinGen:CA16612042	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.150+7T>G	6389	SDHA	Likely benign	1734837376	RCV001404311;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223690	223690	223690	-
NM_004168.4(SDHA):c.150+9A>G	6389	SDHA	Likely benign	1553997201	RCV000559846;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	223692	223692	NC_000005.9:g.223692A>G	ClinGen:CA658657417	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.150+12C>G	6389	SDHA	Likely benign	773966272	RCV002167536;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223695	223695	223695	-
NM_004168.4(SDHA):c.150+12C>T	6389	SDHA	Likely benign	773966272	RCV002095492;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223695	223695	223695	-
NM_004168.4(SDHA):c.150+17dup	6389	SDHA	Benign	1734837730	RCV002124620;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	223695	223696	223695	-
NM_004168.4(SDHA):c.150+14T>G	6389	SDHA	Likely benign	-1	RCV002602588;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223697	223697	NC_000005.9:g.223697T>G	-
NM_004168.4(SDHA):c.150+15T>C	6389	SDHA	Likely benign	1734837973	RCV002169045;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223698	223698	223698	-
NM_004168.4(SDHA):c.150+18G>C	6389	SDHA	Likely benign	759611800	RCV002220289;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	223701	223701	223701	-
NM_004168.4(SDHA):c.151-20G>T	6389	SDHA	Likely benign	2126542228	RCV002095591;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224455	224455	224455	-
NM_004168.4(SDHA):c.151-20G>C	6389	SDHA	Likely benign	2126542228	RCV002218006;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224455	224455	224455	-
NM_004168.4(SDHA):c.151-18T>G	6389	SDHA	Likely benign	-1	RCV003062782;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224457	224457	NC_000005.9:g.224457T>G	-
NM_004168.4(SDHA):c.151-17G>A	6389	SDHA	Likely benign	-1	RCV002800988;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224458	224458	NC_000005.9:g.224458G>A	-
NM_004168.4(SDHA):c.151-16A>C	6389	SDHA	Likely benign	-1	RCV003061561;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224459	224459	NC_000005.9:g.224459A>C	-
NM_004168.4(SDHA):c.151-15A>G	6389	SDHA	Uncertain significance	-1	RCV003074284;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224460	224460	NC_000005.9:g.224460A>G	-
NM_004168.4(SDHA):c.151-9_151-7del	6389	SDHA	Uncertain significance	2126542243	RCV001929708;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	224464	224466	224463	-
NM_004168.4(SDHA):c.151-9C>G	6389	SDHA	Uncertain significance	1734881724	RCV001339871;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224466	224466	224466	-
NM_004168.4(SDHA):c.151-9C>T	6389	SDHA	Uncertain significance	1734881724	RCV001952261;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	224466	224466	224466	-
NM_004168.4(SDHA):c.151-6T>A	6389	SDHA	Likely benign	1352062665	RCV001225521;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224469	224469	5:g.224469T>A	-
NM_004168.4(SDHA):c.151-3C>T	6389	SDHA	Uncertain significance	-1	RCV003121616;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	224472	224472	NC_000005.9:g.224472C>T	-
NM_004168.4(SDHA):c.151-2A>G	6389	SDHA	Likely pathogenic	-1	RCV003086856\|RCV003455712;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224473	224473	NC_000005.9:g.224473A>G	-
NM_004168.4(SDHA):c.151-1G>C	6389	SDHA	Likely pathogenic	1458851277	RCV000560981\|RCV001859971;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224474	224474	NC_000005.9:g.224474G>C	ClinGen:CA359008365	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.154T>A (p.Ser52Thr)	6389	SDHA	Uncertain significance	150326789	RCV000649450\|RCV002397291\|RCV002499110\|RCV003472047;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154; MO	5	224478	224478	NC_000005.9:g.224478T>A	ClinGen:CA3172743	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.155C>T (p.Ser52Phe)	6389	SDHA	Uncertain significance	377470390	RCV000239368\|RCV000565564\|RCV000764599\|RCV001820793\|RCV003313064\|RCV003475849\|RCV003137852;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154; MO	5	224479	224479	NC_000005.9:g.224479C>T	ClinGen:CA3172744	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.159T>C (p.Ala53=)	6389	SDHA	Likely benign	-1	RCV003065281;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224483	224483		-
NM_004168.4(SDHA):c.160C>T (p.Gln54Ter)	6389	SDHA	Pathogenic	1560985916	RCV001236314\|RCV001565032;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MedGen:CN517202	5	224484	224484	5:g.224484C>T	-
NM_004168.4(SDHA):c.162G>A (p.Gln54=)	6389	SDHA	Likely benign	1468436658	RCV000649463\|RCV002397292;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	224486	224486	NC_000005.9:g.224486G>A	ClinGen:CA442690725	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.163T>C (p.Tyr55His)	6389	SDHA	Benign/Likely benign	142926807	RCV000303103\|RCV000360177\|RCV000399750\|RCV000464569\|RCV000570704\|RCV000606498\|RCV003333981\|RCV003316500;	N	MONDO:MONDO:0017366,MedGen:C1708353, Orphanet:29072\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:00136	5	224487	224487	NC_000005.9:g.224487T>C	ClinGen:CA3172745	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.164A>G (p.Tyr55Cys)	6389	SDHA	Uncertain significance	2126542365	RCV002005698;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224488	224488	224488	-
NM_004168.4(SDHA):c.166C>A (p.Pro56Thr)	6389	SDHA	Uncertain significance	2126542374	RCV001963393\|RCV003475261;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	224490	224490	224490	-
NM_004168.4(SDHA):c.167C>T (p.Pro56Leu)	6389	SDHA	Uncertain significance	-1	RCV002300329;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224491	224491	224491	-
NM_004168.4(SDHA):c.168A>G (p.Pro56=)	6389	SDHA	Likely benign	745316978	RCV001438317\|RCV003284327;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	224492	224492	224492	-
NM_004168.4(SDHA):c.169G>T (p.Val57Leu)	6389	SDHA	Uncertain significance	1060503724	RCV000467197\|RCV001012788\|RCV002481483;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072;	5	224493	224493	NC_000005.9:g.224493G>T	ClinGen:CA16611822	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.169G>A (p.Val57Ile)	6389	SDHA	Uncertain significance	1060503724	RCV002044372;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	224493	224493	224493	-
NM_004168.4(SDHA):c.171dup (p.Val58fs)	6389	SDHA	Pathogenic/Likely pathogenic	1553997323	RCV000657509\|RCV001069584;	N	MedGen:CN517202\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224494	224495	NC_000005.9:g.224495dup	-
NM_004168.4(SDHA):c.170T>A (p.Val57Glu)	6389	SDHA	Uncertain significance	1734883606	RCV001337890;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224494	224494	224494	-
NM_004168.4(SDHA):c.173T>G (p.Val58Gly)	6389	SDHA	Uncertain significance	2126542426	RCV001905645\|RCV002397842;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	224497	224497	224497	-
NM_004168.4(SDHA):c.175G>A (p.Asp59Asn)	6389	SDHA	Uncertain significance	-1	RCV002303964;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224499	224499	224499	-
NM_004168.4(SDHA):c.176A>G (p.Asp59Gly)	6389	SDHA	Uncertain significance	775449731	RCV001921055\|RCV002397910;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	224500	224500	224500	-
NM_004168.4(SDHA):c.181G>T (p.Glu61Ter)	6389	SDHA	Pathogenic	1734884330	RCV001037508;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	224505	224505	5:g.224505G>T	-
NM_004168.4(SDHA):c.188A>T (p.Asp63Val)	6389	SDHA	Uncertain significance	1553997327	RCV000549810\|RCV003159902;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	224512	224512	NC_000005.9:g.224512A>T	ClinGen:CA359008452	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.188A>G (p.Asp63Gly)	6389	SDHA	Uncertain significance	1553997327	RCV000702942\|RCV002406634;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	224512	224512	NC_000005.9:g.224512A>G	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.189T>C (p.Asp63=)	6389	SDHA	Likely benign	2126542493	RCV001489795\|RCV002414187;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	224513	224513	224513	-
NM_004168.4(SDHA):c.190G>A (p.Ala64Thr)	6389	SDHA	Uncertain significance	1734884655	RCV001296934;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224514	224514	224514	-
NM_004168.4(SDHA):c.191C>T (p.Ala64Val)	6389	SDHA	Uncertain significance	760510019	RCV000570877\|RCV001048664;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224515	224515	5:g.224515C>T	ClinGen:CA3172749	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.194T>C (p.Val65Ala)	6389	SDHA	Uncertain significance	-1	RCV002300119;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224518	224518	224518	-
NM_004168.4(SDHA):c.195G>A (p.Val65=)	6389	SDHA	Likely benign	2126542556	RCV002097082;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224519	224519	224519	-
NM_004168.4(SDHA):c.198G>A (p.Val66=)	6389	SDHA	Likely benign	1429525714	RCV002190412\|RCV002423319;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	224522	224522	224522	-
NM_004168.4(SDHA):c.200T>C (p.Val67Ala)	6389	SDHA	Uncertain significance	-1	RCV002933773;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224524	224524	NC_000005.9:g.224524T>C	-
NM_004168.4(SDHA):c.202G>A (p.Gly68Ser)	6389	SDHA	Uncertain significance	-1	RCV003009564;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224526	224526	NC_000005.9:g.224526G>A	-
NM_004168.4(SDHA):c.204C>T (p.Gly68=)	6389	SDHA	Conflicting interpretations of pathogenicity	1055082816	RCV000649420\|RCV002422380\|RCV002485461;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; M	5	224528	224528	5:g.224528C>T	ClinGen:CA442690857	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.205G>A (p.Ala69Thr)	6389	SDHA	Uncertain significance	370481102	RCV000234463\|RCV002418011\|RCV003137848\|RCV003417818;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900\|	5	224529	224529	NC_000005.9:g.224529G>A	ClinGen:CA3172750	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.205G>T (p.Ala69Ser)	6389	SDHA	Uncertain significance	-1	RCV003021160;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224529	224529	NC_000005.9:g.224529G>T	-
NM_004168.4(SDHA):c.209G>C (p.Gly70Ala)	6389	SDHA	Uncertain significance	2126542624	RCV002036381;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	224533	224533	224533	-
NM_004168.4(SDHA):c.214dup (p.Ala72fs)	6389	SDHA	Pathogenic	1734887425	RCV001228059;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224534	224535	5:g.224534_224535insG	-
NM_004168.4(SDHA):c.211G>A (p.Gly71Arg)	6389	SDHA	Uncertain significance	1734887299	RCV001240524;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224535	224535	5:g.224535G>A	-
NM_004168.4(SDHA):c.215C>T (p.Ala72Val)	6389	SDHA	Uncertain significance	1204881025	RCV001885549;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224539	224539	224539	-
NM_004168.4(SDHA):c.216A>G (p.Ala72=)	6389	SDHA	Likely benign	1734887844	RCV001502854\|RCV002424934;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	224540	224540	224540	-
NM_004168.4(SDHA):c.218G>T (p.Gly73Val)	6389	SDHA	Uncertain significance	1553997347	RCV000565207\|RCV001222332;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224542	224542	NC_000005.9:g.224542G>T	ClinGen:CA359008510	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.219C>G (p.Gly73=)	6389	SDHA	Likely benign	776288745	RCV000228306\|RCV001014761;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	224543	224543	5:g.224543C>G	ClinGen:CA3172751	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.220T>C (p.Leu74=)	6389	SDHA	Likely benign	-1	RCV003020674;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224544	224544		-
NM_004168.4(SDHA):c.221T>C (p.Leu74Ser)	6389	SDHA	Uncertain significance	763220651	RCV001049640;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	224545	224545	5:g.224545T>C	-
NM_004168.4(SDHA):c.222G>C (p.Leu74Phe)	6389	SDHA	Uncertain significance	-1	RCV002776502;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224546	224546	NC_000005.9:g.224546G>C	-
NM_004168.4(SDHA):c.223C>T (p.Arg75Ter)	6389	SDHA	Pathogenic/Likely pathogenic	781764920	RCV000191050\|RCV000481058\|RCV000575496\|RCV000684793\|RCV002492875\|RCV003474945;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165	5	224547	224547	5:g.224547C>T	ClinGen:CA276119,OMIM:600857.0010	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.224G>A (p.Arg75Gln)	6389	SDHA	Uncertain significance	751645963	RCV001014928\|RCV001362073;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224548	224548	5:g.224548G>A	-
NM_004168.4(SDHA):c.227C>T (p.Ala76Val)	6389	SDHA	Uncertain significance	1734888838	RCV001984674;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224551	224551	224551	-
NM_004168.4(SDHA):c.228T>G (p.Ala76=)	6389	SDHA	Likely benign	1416043203	RCV001423915\|RCV002456692;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	224552	224552	224552	-
NM_004168.4(SDHA):c.233T>C (p.Phe78Ser)	6389	SDHA	Uncertain significance	-1	RCV002922102;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224557	224557	NC_000005.9:g.224557T>C	-
NM_004168.4(SDHA):c.236G>A (p.Gly79Asp)	6389	SDHA	Uncertain significance	759568419	RCV001048302\|RCV002451194;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	224560	224560	5:g.224560G>A	-
NM_004168.4(SDHA):c.237C>T (p.Gly79=)	6389	SDHA	Likely benign	767927763	RCV002185961;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224561	224561	224561	-
NM_004168.4(SDHA):c.240T>C (p.Leu80=)	6389	SDHA	Likely benign	2126542884	RCV002190922\|RCV002454568;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	224564	224564	224564	-
NM_004168.4(SDHA):c.242C>T (p.Ser81Phe)	6389	SDHA	Uncertain significance	1553997357	RCV000546249;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	224566	224566	NC_000005.9:g.224566C>T	ClinGen:CA359008555	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.242_243insA (p.Ser81_Glu82insTer)	6389	SDHA	Pathogenic	2126542910	RCV001381899\|RCV002456598\|RCV003148988;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224566	224567	224566	-
NM_004168.4(SDHA):c.243T>C (p.Ser81=)	6389	SDHA	Likely benign	-1	RCV002460027\|RCV003101821;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224567	224567		-
NM_004168.4(SDHA):c.245_252del (p.Glu82fs)	6389	SDHA	Pathogenic	1734890180	RCV001218717;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224568	224575	5:g.224568_224575del	-
NM_004168.4(SDHA):c.249A>G (p.Ala83=)	6389	SDHA	Likely benign	1560986107	RCV000976609\|RCV002427407;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	224573	224573	5:g.224573A>G	-
NM_004168.4(SDHA):c.250G>A (p.Gly84Arg)	6389	SDHA	Uncertain significance	2126542993	RCV001982263;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224574	224574	224574	-
NM_004168.4(SDHA):c.250G>C (p.Gly84Arg)	6389	SDHA	Uncertain significance	-1	RCV002792033;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224574	224574	NC_000005.9:g.224574G>C	-
NM_004168.4(SDHA):c.251G>A (p.Gly84Glu)	6389	SDHA	Uncertain significance	199615452	RCV001877331;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	224575	224575	224575	-
NM_004168.4(SDHA):c.253_256dup (p.Asn86delinsIleTer)	6389	SDHA	Pathogenic	1560986132	RCV000698951;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224576	224577	NC_000005.9:g.224577_224580dup	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.252G>T (p.Gly84=)	6389	SDHA	Likely benign	753293451	RCV001243121\|RCV002430032;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	224576	224576	5:g.224576G>T	-
NM_004168.4(SDHA):c.252G>A (p.Gly84=)	6389	SDHA	Likely benign	753293451	RCV001439510\|RCV002456728;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	224576	224576	224576	-
NM_004168.4(SDHA):c.252G>C (p.Gly84=)	6389	SDHA	Likely benign	753293451	RCV001463522;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224576	224576	224576	-
NM_004168.4(SDHA):c.256A>G (p.Asn86Asp)	6389	SDHA	Uncertain significance	200519133	RCV001069653;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224580	224580	5:g.224580A>G	-
NM_004168.4(SDHA):c.257A>G (p.Asn86Ser)	6389	SDHA	Uncertain significance	2126543056	RCV001866664;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	224581	224581	224581	-
NM_004168.4(SDHA):c.260C>T (p.Thr87Ile)	6389	SDHA	Uncertain significance	756543943	RCV000649443\|RCV002440349\|RCV003324782\|RCV003472045;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642	5	224584	224584	NC_000005.9:g.224584C>T	ClinGen:CA3172758	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.261A>G (p.Thr87=)	6389	SDHA	Likely benign	2126543070	RCV002107921;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	224585	224585	224585	-
NM_004168.4(SDHA):c.261A>C (p.Thr87=)	6389	SDHA	Likely benign	-1	RCV003059178\|RCV003170918;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	224585	224585		-
NM_004168.4(SDHA):c.262G>A (p.Ala88Thr)	6389	SDHA	Uncertain significance	2126543077	RCV002046360;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224586	224586	224586	-
NM_004168.4(SDHA):c.263C>G (p.Ala88Gly)	6389	SDHA	Uncertain significance	1734891785	RCV001228307\|RCV001751443;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MedGen:CN517202	5	224587	224587	5:g.224587C>G	-
NM_004168.4(SDHA):c.263C>T (p.Ala88Val)	6389	SDHA	Uncertain significance	1734891785	RCV001997624;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224587	224587	224587	-
NM_004168.4(SDHA):c.266G>A (p.Cys89Tyr)	6389	SDHA	Uncertain significance	138016874	RCV001365305\|RCV002438848\|RCV003473885;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	224590	224590	224590	-
NM_004168.4(SDHA):c.267T>A (p.Cys89Ter)	6389	SDHA	Pathogenic	1579381753	RCV001016312\|RCV001221035;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224591	224591	5:g.224591T>A	-
NM_004168.4(SDHA):c.268G>A (p.Val90Ile)	6389	SDHA	Uncertain significance	2126543120	RCV001873104;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	224592	224592	224592	-
NM_004168.4(SDHA):c.269T>C (p.Val90Ala)	6389	SDHA	Uncertain significance	886060514	RCV000267910\|RCV000297336\|RCV000354574;	N	MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0017366,MedGen:C1708353, Orphanet:29072	5	224593	224593	NC_000005.9:g.224593T>C	ClinGen:CA10624326	C0023264 256000 Leigh syndrome;
NM_004168.4(SDHA):c.272C>T (p.Thr91Ile)	6389	SDHA	Uncertain significance	-1	RCV002644380\|RCV003475517;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	224596	224596	NC_000005.9:g.224596C>T	-
NM_004168.4(SDHA):c.273C>A (p.Thr91=)	6389	SDHA	Likely benign	2126543162	RCV001439489;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224597	224597	224597	-
NM_004168.4(SDHA):c.274A>C (p.Lys92Gln)	6389	SDHA	Uncertain significance	1734892884	RCV001037040;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	224598	224598	5:g.224598A>C	-
NM_004168.4(SDHA):c.275A>G (p.Lys92Arg)	6389	SDHA	Uncertain significance	778267118	RCV002024507;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224599	224599	224599	-
NM_004168.4(SDHA):c.276G>C (p.Lys92Asn)	6389	SDHA	Uncertain significance	375298039	RCV001065659\|RCV002436661;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	224600	224600	5:g.224600G>C	-
NM_004168.4(SDHA):c.276G>A (p.Lys92=)	6389	SDHA	Likely benign	375298039	RCV001451721\|RCV002439066;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	224600	224600	224600	-
NM_004168.4(SDHA):c.278T>C (p.Leu93Pro)	6389	SDHA	Uncertain significance	1326611328	RCV001904024;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224602	224602	224602	-
NM_004168.4(SDHA):c.283C>G (p.Pro95Ala)	6389	SDHA	Uncertain significance	-1	RCV003050739;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224607	224607	NC_000005.9:g.224607C>G	-
NM_004168.4(SDHA):c.284C>G (p.Pro95Arg)	6389	SDHA	Conflicting interpretations of pathogenicity	1553997377	RCV000570222\|RCV000558917;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	224608	224608	NC_000005.9:g.224608C>G	ClinGen:CA359008642	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.285T>C (p.Pro95=)	6389	SDHA	Likely benign	2126543225	RCV002140638\|RCV002434567;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	224609	224609	224609	-
NM_004168.4(SDHA):c.286A>G (p.Thr96Ala)	6389	SDHA	Uncertain significance	-1	RCV002932538;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224610	224610	NC_000005.9:g.224610A>G	-
NM_004168.4(SDHA):c.287C>T (p.Thr96Ile)	6389	SDHA	Uncertain significance	377620054	RCV000231817\|RCV000569754\|RCV000663057\|RCV000761150\|RCV000786220;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|	5	224611	224611	NC_000005.9:g.224611C>T	ClinGen:CA3172761	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.290G>C (p.Arg97Thr)	6389	SDHA	Uncertain significance	371274523	RCV000649462\|RCV002440350\|RCV003420138;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|	5	224614	224614	NC_000005.9:g.224614G>C	ClinGen:CA3172762	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.291G>A (p.Arg97=)	6389	SDHA	Likely benign	-1	RCV002439942\|RCV003102879;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224615	224615		-
NM_004168.4(SDHA):c.293C>T (p.Ser98Leu)	6389	SDHA	Uncertain significance	1579381851	RCV000801045\|RCV001329183\|RCV003166199;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	224617	224617	5:g.224617C>T	-
NM_004168.4(SDHA):c.298_299del (p.Thr100fs)	6389	SDHA	Pathogenic/Likely pathogenic	2126543272	RCV001958646\|RCV002256871;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	224617	224618	224616	-
NM_004168.4(SDHA):c.296A>G (p.His99Arg)	6389	SDHA	Uncertain significance	1579381882	RCV000798855;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224620	224620	5:g.224620A>G	-
NM_004168.4(SDHA):c.297C>T (p.His99=)	6389	SDHA	Likely benign	-1	RCV002442194\|RCV003102941;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224621	224621		-
NM_004168.4(SDHA):c.300T>C (p.Thr100=)	6389	SDHA	Likely benign	771662494	RCV000461867\|RCV001018051;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	224624	224624	NC_000005.9:g.224624T>C	ClinGen:CA3172764	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.303T>G (p.Val101=)	6389	SDHA	Likely benign	2126543357	RCV001456082\|RCV003298782;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	224627	224627	224627	-
NM_004168.4(SDHA):c.303T>C (p.Val101=)	6389	SDHA	Likely benign	-1	RCV003025582;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224627	224627		-
NM_004168.4(SDHA):c.304_305delinsAT (p.Ala102Ile)	6389	SDHA	Uncertain significance	1734896344	RCV001238075;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224628	224629	NC_000005.9:g.224628_224629delinsAT	-
NM_004168.4(SDHA):c.305C>T (p.Ala102Val)	6389	SDHA	Uncertain significance	1240528592	RCV001064465\|RCV003160529;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	224629	224629	5:g.224629C>T	-
NM_004168.4(SDHA):c.306A>G (p.Ala102=)	6389	SDHA	Likely benign	2126543388	RCV001394481\|RCV002449089;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	224630	224630	224630	-
NM_004168.4(SDHA):c.306A>T (p.Ala102=)	6389	SDHA	Likely benign	2126543388	RCV001484330;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224630	224630	224630	-
NM_004168.4(SDHA):c.310_311dup (p.Gln104fs)	6389	SDHA	Pathogenic	876658637	RCV000216352\|RCV002518274;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224631	224632	NC_000005.9:g.224632CA[3]	ClinGen:CA10578625	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.308_309inv (p.Ala103Val)	6389	SDHA	Conflicting interpretations of pathogenicity	-1	RCV001312570\|RCV002319698;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	224632	224633	224632	-
NM_004168.4(SDHA):c.309A>G (p.Ala103=)	6389	SDHA	Benign	1139424	RCV000118318\|RCV000162942\|RCV000261547\|RCV000319629\|RCV000385778\|RCV001509667\|RCV001705861\|RCV003315682;	N	MedGen:CN169374\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506\|MONDO:MONDO:0017366,MedGen:C1708353, Orphanet:29072\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:320	5	224633	224633	5:g.224633A>G	ClinGen:CA155154	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.310C>T (p.Gln104Ter)	6389	SDHA	Pathogenic	1423978863	RCV001018677\|RCV001383484;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224634	224634	5:g.224634C>T	-
NM_004168.4(SDHA):c.312G>A (p.Gln104=)	6389	SDHA	Conflicting interpretations of pathogenicity	2126543437	RCV001939725\|RCV003382703;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	224636	224636	224636	-
NM_004168.4(SDHA):c.312+1G>A	6389	SDHA	Likely pathogenic	2126543441	RCV002018663;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224637	224637	224637	-
NM_004168.4(SDHA):c.312+4A>C	6389	SDHA	Uncertain significance	-1	RCV002320489\|RCV003099215;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224640	224640	224640	-
NM_004168.4(SDHA):c.312+5G>A	6389	SDHA	Uncertain significance	1384659459	RCV001991159;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	224641	224641	224641	-
NM_004168.4(SDHA):c.312+5G>C	6389	SDHA	Uncertain significance	-1	RCV002872079\|RCV003308310;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	224641	224641	NC_000005.9:g.224641G>C	-
NM_004168.4(SDHA):c.312+7G>T	6389	SDHA	Likely benign	2126543454	RCV001399704;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224643	224643	224643	-
NM_004168.4(SDHA):c.312+7G>C	6389	SDHA	Likely benign	2126543454	RCV002071416;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	224643	224643	224643	-
NM_004168.4(SDHA):c.312+11G>C	6389	SDHA	Likely benign	2126543478	RCV002157950;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224647	224647	224647	-
NM_004168.4(SDHA):c.312+15C>A	6389	SDHA	Uncertain significance	1180146041	RCV002013200;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224651	224651	224651	-
NM_004168.4(SDHA):c.312+16C>T	6389	SDHA	Likely benign	771169259	RCV002155618;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224652	224652	224652	-
NM_004168.4(SDHA):c.312+16C>G	6389	SDHA	Likely benign	-1	RCV002610244;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224652	224652	NC_000005.9:g.224652C>G	-
NM_004168.4(SDHA):c.312+17C>T	6389	SDHA	Likely benign	1734898561	RCV002145321;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224653	224653	224653	-
NM_004168.4(SDHA):c.312+18C>T	6389	SDHA	Likely benign	-1	RCV003077835;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224654	224654	NC_000005.9:g.224654C>T	-
NM_004168.4(SDHA):c.312+20C>T	6389	SDHA	Conflicting interpretations of pathogenicity	111533078	RCV002077205\|RCV003238458;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MedGen:C3661900	5	224656	224656	224656	-
NM_004168.4(SDHA):c.312+20C>A	6389	SDHA	Likely benign	111533078	RCV002095679;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	224656	224656	224656	-
NM_004168.4(SDHA):c.313-19G>T	6389	SDHA	Conflicting interpretations of pathogenicity	185555941	RCV000411801\|RCV000443248\|RCV001528662\|RCV002058842\|RCV003168597;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MedGen:CN169374\|MedGen:C3661900\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,	5	225515	225515	5:g.225515G>T	ClinGen:CA3172796	CN169374 not specified;
NM_004168.4(SDHA):c.313-18A>C	6389	SDHA	Likely benign	1579383789	RCV002170413;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	225516	225516	225516	-
NM_004168.4(SDHA):c.313-13T>C	6389	SDHA	Uncertain significance	-1	RCV002838155;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225521	225521	NC_000005.9:g.225521T>C	-
NM_004168.4(SDHA):c.313-11G>A	6389	SDHA	Uncertain significance	1734951831	RCV001888701;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	225523	225523	225523	-
NM_004168.4(SDHA):c.313-10G>A	6389	SDHA	Likely benign	1579383848	RCV000798776;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225524	225524	5:g.225524G>A	-
NM_004168.4(SDHA):c.313-8G>A	6389	SDHA	Likely benign	1060503710	RCV000458845;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	225526	225526	NC_000005.9:g.225526G>A	ClinGen:CA16611864	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.313-7T>C	6389	SDHA	Likely benign	201972549	RCV000465323\|RCV002323758;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	225527	225527	NC_000005.9:g.225527T>C	ClinGen:CA16612044	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.313-6T>C	6389	SDHA	Likely benign	1579383890	RCV001479131;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225528	225528	5:g.225528T>C	-
NM_004168.4(SDHA):c.313-5T>G	6389	SDHA	Uncertain significance	1060503705	RCV000459906;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	225529	225529	NC_000005.9:g.225529T>G	ClinGen:CA16612045	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.313-4C>T	6389	SDHA	Likely benign	1368657380	RCV000881226\|RCV002320062;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	225530	225530	5:g.225530C>T	-
NM_004168.4(SDHA):c.313-4C>G	6389	SDHA	Likely benign	1368657380	RCV001018765\|RCV001426122;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225530	225530	5:g.225530C>G	-
NM_004168.4(SDHA):c.313-3C>T	6389	SDHA	Conflicting interpretations of pathogenicity	1553997584	RCV000534970\|RCV000572784;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	225531	225531	NC_000005.9:g.225531C>T	ClinGen:CA658657418	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.313G>A (p.Gly105Arg)	6389	SDHA	Uncertain significance	2126546583	RCV001980030;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	225534	225534	225534	-
NM_004168.4(SDHA):c.314_315delinsTT (p.Gly105Val)	6389	SDHA	Uncertain significance	1734953252	RCV001217978;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225535	225536	NC_000005.9:g.225535_225536delinsTT	-
NM_004168.4(SDHA):c.316G>C (p.Gly106Arg)	6389	SDHA	Uncertain significance	1579383936	RCV000797368;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225537	225537	5:g.225537G>C	-
NM_004168.4(SDHA):c.319A>G (p.Ile107Val)	6389	SDHA	Uncertain significance	1060503720	RCV000462764\|RCV000566699;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	225540	225540	NC_000005.9:g.225540A>G	ClinGen:CA16611823	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.320T>A (p.Ile107Asn)	6389	SDHA	Uncertain significance	1734953616	RCV001042880;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	225541	225541	5:g.225541T>A	-
NM_004168.4(SDHA):c.320T>G (p.Ile107Ser)	6389	SDHA	Uncertain significance	1734953616	RCV001238881;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225541	225541	5:g.225541T>G	-
NM_004168.4(SDHA):c.321C>G (p.Ile107Met)	6389	SDHA	Uncertain significance	1734953765	RCV001248524\|RCV002322166;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	225542	225542	5:g.225542C>G	-
NM_004168.4(SDHA):c.322_323del (p.Asn108fs)	6389	SDHA	Pathogenic/Likely pathogenic	2126546657	RCV001931700\|RCV002259153;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	225543	225544	225542	-
NM_004168.4(SDHA):c.323A>G (p.Asn108Ser)	6389	SDHA	Uncertain significance	758086385	RCV000469628\|RCV001019353;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	225544	225544	NC_000005.9:g.225544A>G	ClinGen:CA3172800	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.328G>C (p.Ala110Pro)	6389	SDHA	Uncertain significance	786205209	RCV001351460;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225549	225549	NC_000005.9:g.225549G>C	ClinVar:190221	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.329C>T (p.Ala110Val)	6389	SDHA	Uncertain significance	-1	RCV003042705;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225550	225550	NC_000005.9:g.225550C>T	-
NM_004168.4(SDHA):c.334G>A (p.Gly112Arg)	6389	SDHA	Uncertain significance	751114575	RCV000472280;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225555	225555	NC_000005.9:g.225555G>A	ClinGen:CA3172802	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.336G>C (p.Gly112=)	6389	SDHA	Likely benign	375645919	RCV000548300\|RCV002456217;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	225557	225557	NC_000005.9:g.225557G>C	ClinGen:CA112815542	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.336G>A (p.Gly112=)	6389	SDHA	Likely benign	-1	RCV002857070\|RCV003340541;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	225557	225557		-
NM_004168.4(SDHA):c.337A>G (p.Asn113Asp)	6389	SDHA	Uncertain significance	1450249875	RCV001972890\|RCV003303527;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	225558	225558	225558	-
NM_004168.4(SDHA):c.338A>G (p.Asn113Ser)	6389	SDHA	Uncertain significance	1734955271	RCV001215082;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225559	225559	5:g.225559A>G	-
NM_004168.4(SDHA):c.338A>T (p.Asn113Ile)	6389	SDHA	Uncertain significance	1734955271	RCV001248525\|RCV002451617;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	225559	225559	5:g.225559A>T	-
NM_004168.4(SDHA):c.338A>C (p.Asn113Thr)	6389	SDHA	Uncertain significance	1734955271	RCV001876644;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	225559	225559	225559	-
NM_004168.4(SDHA):c.339C>T (p.Asn113=)	6389	SDHA	Likely benign	-1	RCV002666720;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225560	225560		-
NM_004168.4(SDHA):c.340A>G (p.Met114Val)	6389	SDHA	Uncertain significance	933414586	RCV000649403\|RCV002458123\|RCV002485460;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; M	5	225561	225561	5:g.225561A>G	ClinGen:CA112815549	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.341T>A (p.Met114Lys)	6389	SDHA	Uncertain significance	-1	RCV003026823;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225562	225562	NC_000005.9:g.225562T>A	-
NM_004168.4(SDHA):c.342GGA[2] (p.Glu116del)	6389	SDHA	Uncertain significance	1734955897	RCV001989991;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225563	225565	225562	-
NM_004168.4(SDHA):c.345G>C (p.Glu115Asp)	6389	SDHA	Uncertain significance	368286780	RCV001228080\|RCV002451534;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	225566	225566	5:g.225566G>C	-
NM_004168.4(SDHA):c.345G>A (p.Glu115=)	6389	SDHA	Likely benign	368286780	RCV001469188\|RCV002460161;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	225566	225566	225566	-
NM_004168.4(SDHA):c.348G>A (p.Glu116=)	6389	SDHA	Likely benign	2126546824	RCV002177199\|RCV002454348;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	225569	225569	225569	-
NM_004168.4(SDHA):c.349G>A (p.Asp117Asn)	6389	SDHA	Uncertain significance	2126546832	RCV002028208;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	225570	225570	225570	-
NM_004168.4(SDHA):c.350A>G (p.Asp117Gly)	6389	SDHA	Uncertain significance	1579384062	RCV000818402;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225571	225571	5:g.225571A>G	-
NM_004168.4(SDHA):c.351C>T (p.Asp117=)	6389	SDHA	Likely benign	1579384072	RCV001406492\|RCV002454148;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	225572	225572	5:g.225572C>T	-
NM_004168.4(SDHA):c.353A>G (p.Asn118Ser)	6389	SDHA	Uncertain significance	987288514	RCV001935816\|RCV003167192;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	225574	225574	225574	-
NM_004168.4(SDHA):c.354C>T (p.Asn118=)	6389	SDHA	Likely benign	923803277	RCV000973738\|RCV002337016;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	225575	225575	5:g.225575C>T	-
NM_004168.4(SDHA):c.355T>C (p.Trp119Arg)	6389	SDHA	Uncertain significance	1734957208	RCV001349827;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225576	225576	225576	-
NM_004168.4(SDHA):c.356G>A (p.Trp119Ter)	6389	SDHA	Pathogenic	1734957331	RCV001062355\|RCV001799730\|RCV002451264\|RCV003235460\|RCV003455281;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|Human Phenotype Ontology:HP:0100723,MONDO:MONDO:0011719,MeSH:D046152,MedGen:C0238198,OMIM:606764, Orphanet:44890\|MONDO:MONDO:0015	5	225577	225577	5:g.225577G>A	-
NM_004168.4(SDHA):c.359G>A (p.Arg120Lys)	6389	SDHA	Uncertain significance	2126546923	RCV002033777;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225580	225580	225580	-
NM_004168.4(SDHA):c.360G>A (p.Arg120=)	6389	SDHA	Likely benign	1247649190	RCV001474605\|RCV002456824;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	225581	225581	225581	-
NM_004168.4(SDHA):c.364C>A (p.His122Asn)	6389	SDHA	Uncertain significance	-1	RCV003004949;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225585	225585	NC_000005.9:g.225585C>A	-
NM_004168.4(SDHA):c.365A>G (p.His122Arg)	6389	SDHA	Uncertain significance	1579384131	RCV000816860\|RCV002495158\|RCV003307530;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154; MONDO	5	225586	225586	5:g.225586A>G	-
NM_004168.4(SDHA):c.369C>G (p.Phe123Leu)	6389	SDHA	Uncertain significance	1579384137	RCV001020912\|RCV001373562;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225590	225590	5:g.225590C>G	-
NM_004168.4(SDHA):c.370T>C (p.Tyr124His)	6389	SDHA	Uncertain significance	2126546996	RCV001936982;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	225591	225591	225591	-
NM_004168.4(SDHA):c.371A>G (p.Tyr124Cys)	6389	SDHA	Uncertain significance	935241830	RCV000468036\|RCV002349988;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	225592	225592	NC_000005.9:g.225592A>G	ClinGen:CA16611927	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.372C>T (p.Tyr124=)	6389	SDHA	Likely benign	754393360	RCV000460760\|RCV001020988\|RCV003431041;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	5	225593	225593	NC_000005.9:g.225593C>T	ClinGen:CA3172803	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.373G>A (p.Asp125Asn)	6389	SDHA	Uncertain significance	780654623	RCV000528854\|RCV002350354\|RCV001821586;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN169374	5	225594	225594	NC_000005.9:g.225594G>A	ClinGen:CA3172804	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.373G>C (p.Asp125His)	6389	SDHA	Uncertain significance	780654623	RCV001021015\|RCV001205740;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225594	225594	5:g.225594G>C	-
NM_004168.4(SDHA):c.378del (p.Thr126_Val127insTer)	6389	SDHA	Pathogenic/Likely pathogenic	1553997617	RCV000539370\|RCV001021144\|RCV003151099\|RCV003419981\|RCV003476304;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900\|\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:61364	5	225598	225598	NC_000005.9:g.225599del	ClinGen:CA658657419	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.378C>T (p.Thr126=)	6389	SDHA	Likely benign	756039268	RCV000469212\|RCV002367621;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	225599	225599	NC_000005.9:g.225599C>T	ClinGen:CA3172806	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.379G>A (p.Val127Met)	6389	SDHA	Uncertain significance	777600956	RCV000473055\|RCV000569237;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	225600	225600	NC_000005.9:g.225600G>A	ClinGen:CA3172807	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.386G>A (p.Gly129Asp)	6389	SDHA	Uncertain significance	2126547166	RCV001899967;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225607	225607	225607	-
NM_004168.4(SDHA):c.389C>G (p.Ser130Cys)	6389	SDHA	Uncertain significance	1553997625	RCV000537028\|RCV002358583;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	225610	225610	NC_000005.9:g.225610C>G	ClinGen:CA359009441	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.390C>T (p.Ser130=)	6389	SDHA	Likely benign	748976493	RCV000571960\|RCV000649489;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225611	225611	5:g.225611C>T	ClinGen:CA3172808	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.392_396dup (p.Leu133fs)	6389	SDHA	Pathogenic	2126547233	RCV001866474;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225611	225612	225611	-
NM_004168.4(SDHA):c.391G>A (p.Asp131Asn)	6389	SDHA	Uncertain significance	1324014370	RCV000575285\|RCV000691087\|RCV001800774;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MedGen:C3661900	5	225612	225612	5:g.225612G>A	ClinGen:CA359009446	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.392A>G (p.Asp131Gly)	6389	SDHA	Uncertain significance	2126547239	RCV001902435;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225613	225613	225613	-
NM_004168.4(SDHA):c.396G>T (p.Trp132Cys)	6389	SDHA	Uncertain significance	1734960239	RCV001228234\|RCV003284086\|RCV003473794;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	225617	225617	5:g.225617G>T	-
NM_004168.4(SDHA):c.397C>T (p.Leu133=)	6389	SDHA	Uncertain significance	2126547261	RCV001914418;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225618	225618	225618	-
NM_004168.4(SDHA):c.397C>G (p.Leu133Val)	6389	SDHA	Uncertain significance	2126547261	RCV003094257\|RCV002259255;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	225618	225618	225618	-
NM_004168.4(SDHA):c.403del (p.Asp135fs)	6389	SDHA	Pathogenic	-1	RCV003070967\|RCV003316881\|RCV003340601;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	225620	225620	NC_000005.9:g.225624del	-
NM_004168.4(SDHA):c.401G>T (p.Gly134Val)	6389	SDHA	Uncertain significance	-1	RCV003060696;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225622	225622	NC_000005.9:g.225622G>T	-
NM_004168.4(SDHA):c.403G>A (p.Asp135Asn)	6389	SDHA	Uncertain significance	1734960553	RCV001152038\|RCV001152037\|RCV001152036\|RCV001206474\|RCV002355125;	N	MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0017366,MedGen:C1708353, Orphanet:29072\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:00136	5	225624	225624	5:g.225624G>A	-
NM_004168.4(SDHA):c.406C>G (p.Gln136Glu)	6389	SDHA	Uncertain significance	1365359024	RCV002024752\|RCV002291797;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225627	225627	225627	-
NM_004168.4(SDHA):c.407A>T (p.Gln136Leu)	6389	SDHA	Uncertain significance	876660259	RCV000213542\|RCV002519727;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225628	225628	5:g.225628A>T	ClinGen:CA10578626	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.408G>A (p.Gln136=)	6389	SDHA	Likely benign	190477316	RCV000469927\|RCV000567403;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	225629	225629	NC_000005.9:g.225629G>A	ClinGen:CA3172811	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.409G>T (p.Asp137Tyr)	6389	SDHA	Uncertain significance	1734961262	RCV001221891\|RCV003380898;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	225630	225630	5:g.225630G>T	-
NM_004168.4(SDHA):c.411T>A (p.Asp137Glu)	6389	SDHA	Uncertain significance	1444399160	RCV000525177;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	225632	225632	NC_000005.9:g.225632T>A	ClinGen:CA359009538	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.411T>G (p.Asp137Glu)	6389	SDHA	Uncertain significance	1444399160	RCV001993997\|RCV002324437\|RCV003475267;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	225632	225632	225632	-
NM_004168.4(SDHA):c.412G>A (p.Ala138Thr)	6389	SDHA	Uncertain significance	-1	RCV002581147;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225633	225633	NC_000005.9:g.225633G>A	-
NM_004168.4(SDHA):c.413C>T (p.Ala138Val)	6389	SDHA	Uncertain significance	1342456775	RCV000542175;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	225634	225634	NC_000005.9:g.225634C>T	ClinGen:CA359009551	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.414C>T (p.Ala138=)	6389	SDHA	Likely benign	1219265195	RCV001455176;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225635	225635	5:g.225635C>T	-
NM_004168.4(SDHA):c.415A>G (p.Ile139Val)	6389	SDHA	Uncertain significance	-1	RCV002653993;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225636	225636	NC_000005.9:g.225636A>G	-
NM_004168.4(SDHA):c.419A>G (p.His140Arg)	6389	SDHA	Uncertain significance	759266253	RCV000457011;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	225640	225640	NC_000005.9:g.225640A>G	ClinGen:CA16611928	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.420C>G (p.His140Gln)	6389	SDHA	Uncertain significance	747232441	RCV001965053;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	225641	225641	225641	-
NM_004168.4(SDHA):c.420C>T (p.His140=)	6389	SDHA	Likely benign	747232441	RCV002072839;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225641	225641	225641	-
NM_004168.4(SDHA):c.421T>G (p.Tyr141Asp)	6389	SDHA	Uncertain significance	1553997643	RCV000570081\|RCV001342949;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225642	225642	5:g.225642T>G	ClinGen:CA359009582	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.421T>C (p.Tyr141His)	6389	SDHA	Uncertain significance	1553997643	RCV000810217\|RCV002290977;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0031006,MedGen:C5543254,OMIM:619259	5	225642	225642	5:g.225642T>C	-
NM_004168.4(SDHA):c.422A>G (p.Tyr141Cys)	6389	SDHA	Uncertain significance	1377816261	RCV002223477\|RCV002258395\|RCV003101271;	N	MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	225643	225643	225643	-
NM_004168.4(SDHA):c.423C>T (p.Tyr141=)	6389	SDHA	Likely benign	768897373	RCV000234606\|RCV000567577;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	225644	225644	NC_000005.9:g.225644C>T	ClinGen:CA3172813	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.424A>G (p.Met142Val)	6389	SDHA	Uncertain significance	776848209	RCV000457452\|RCV001755708\|RCV002329086\|RCV002481481;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165	5	225645	225645	NC_000005.9:g.225645A>G	ClinGen:CA3172814	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.424A>C (p.Met142Leu)	6389	SDHA	Uncertain significance	776848209	RCV001052974;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225645	225645	5:g.225645A>C	-
NM_004168.4(SDHA):c.425_426delinsAC (p.Met142Asn)	6389	SDHA	Uncertain significance	2126547518	RCV001921863;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	225646	225647	225646	-
NM_004168.4(SDHA):c.428C>T (p.Thr143Met)	6389	SDHA	Uncertain significance	200675907	RCV000471253\|RCV001022221\|RCV001821297\|RCV003476129;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN169374\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642	5	225649	225649	NC_000005.9:g.225649C>T	ClinGen:CA16612048	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.429G>A (p.Thr143=)	6389	SDHA	Likely benign	906281170	RCV000550383\|RCV002330949;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	225650	225650	NC_000005.9:g.225650G>A	ClinGen:CA112815664	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.429G>T (p.Thr143=)	6389	SDHA	Likely benign	906281170	RCV001503986;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225650	225650	225650	-
NM_004168.4(SDHA):c.433C>G (p.Gln145Glu)	6389	SDHA	Uncertain significance	765784494	RCV002028300\|RCV002331590;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	225654	225654	225654	-
NM_004168.4(SDHA):c.434A>G (p.Gln145Arg)	6389	SDHA	Uncertain significance	-1	RCV002880440;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225655	225655	NC_000005.9:g.225655A>G	-
NM_004168.4(SDHA):c.436G>C (p.Ala146Pro)	6389	SDHA	Uncertain significance	-1	RCV002303954;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225657	225657	225657	-
NM_004168.4(SDHA):c.436G>A (p.Ala146Thr)	6389	SDHA	Uncertain significance	-1	RCV002909370;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225657	225657	NC_000005.9:g.225657G>A	-
NM_004168.4(SDHA):c.437C>T (p.Ala146Val)	6389	SDHA	Uncertain significance	1060503714	RCV000472132\|RCV003362797;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	225658	225658	NC_000005.9:g.225658C>T	ClinGen:CA16611930	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.439C>T (p.Pro147Ser)	6389	SDHA	Uncertain significance	1734963793	RCV002025413;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	225660	225660	225660	-
NM_004168.4(SDHA):c.440C>A (p.Pro147His)	6389	SDHA	Uncertain significance	763191656	RCV000811030;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225661	225661	5:g.225661C>A	-
NM_004168.4(SDHA):c.441C>T (p.Pro147=)	6389	SDHA	Conflicting interpretations of pathogenicity	201453889	RCV000233726\|RCV000332396\|RCV000389166\|RCV000274933\|RCV000564203;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO	5	225662	225662	5:g.225662C>T	ClinGen:CA3172819	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.441C>A (p.Pro147=)	6389	SDHA	Likely benign	201453889	RCV001480701;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	225662	225662	225662	-
NM_004168.4(SDHA):c.442G>A (p.Ala148Thr)	6389	SDHA	Conflicting interpretations of pathogenicity	375576259	RCV000228365\|RCV000287726\|RCV000345164\|RCV000383376\|RCV000572868\|RCV003475076;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506\|MONDO:MONDO:0017366,MedGen:C1708353, Orphanet:29072\|MONDO:MONDO:0100	5	225663	225663	5:g.225663G>A	ClinGen:CA3172820	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.442G>T (p.Ala148Ser)	6389	SDHA	Uncertain significance	375576259	RCV001895502;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	225663	225663	225663	-
NM_004168.4(SDHA):c.444C>T (p.Ala148=)	6389	SDHA	Likely benign	367618662	RCV000570539\|RCV000649472;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225665	225665	5:g.225665C>T	ClinGen:CA3172821	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.444C>G (p.Ala148=)	6389	SDHA	Likely benign	367618662	RCV002170235\|RCV002331674;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	225665	225665	225665	-
NM_004168.4(SDHA):c.445G>A (p.Ala149Thr)	6389	SDHA	Uncertain significance	575617625	RCV000571754\|RCV000764600\|RCV000702947;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MO	5	225666	225666	5:g.225666G>A	ClinGen:CA3172822	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.446C>T (p.Ala149Val)	6389	SDHA	Uncertain significance	1060503709	RCV000473445;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	225667	225667	NC_000005.9:g.225667C>T	ClinGen:CA16612049	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.447del (p.Val150fs)	6389	SDHA	Pathogenic	2126547751	RCV001956560;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225667	225667	225666	-
NM_004168.4(SDHA):c.447C>T (p.Ala149=)	6389	SDHA	Likely benign	752187837	RCV000567589\|RCV000649485;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225668	225668	5:g.225668C>T	ClinGen:CA3172823	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.447C>G (p.Ala149=)	6389	SDHA	Likely benign	752187837	RCV001484797;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225668	225668	5:g.225668C>G	-
NM_004168.4(SDHA):c.447C>A (p.Ala149=)	6389	SDHA	Likely benign	-1	RCV003047880\|RCV003294401;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	225668	225668		-
NM_004168.4(SDHA):c.448G>A (p.Val150Met)	6389	SDHA	Uncertain significance	542980860	RCV000562589\|RCV000695590\|RCV000764601\|RCV003328100\|RCV003471904;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506; MO	5	225669	225669	NC_000005.9:g.225669G>A	ClinGen:CA3172824	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.450G>A (p.Val150=)	6389	SDHA	Uncertain significance	1734965281	RCV001298738;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225671	225671	225671	-
NM_004168.4(SDHA):c.451G>A (p.Val151Ile)	6389	SDHA	Uncertain significance	143148642	RCV000232272\|RCV002338729\|RCV003417819;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|	5	225672	225672	5:g.225672G>A	ClinGen:CA3172825	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.453C>T (p.Val151=)	6389	SDHA	Likely benign	138917116	RCV000226323\|RCV000603740\|RCV001022667;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MedGen:CN169374\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	225674	225674	5:g.225674C>T	ClinGen:CA3172826	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.453C>A (p.Val151=)	6389	SDHA	Conflicting interpretations of pathogenicity	138917116	RCV000475275\|RCV001022664\|RCV003230266;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225674	225674	NC_000005.9:g.225674C>A	ClinGen:CA3172827	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.453C>G (p.Val151=)	6389	SDHA	Likely benign	138917116	RCV000649486\|RCV001022666;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	225674	225674	5:g.225674C>G	ClinGen:CA442691016	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.454G>A (p.Glu152Lys)	6389	SDHA	Uncertain significance	778737664	RCV000526392\|RCV001022683\|RCV002509437\|RCV003231529\|RCV003476313;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|M	5	225675	225675	NC_000005.9:g.225675G>A	ClinGen:CA3172828	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.454G>C (p.Glu152Gln)	6389	SDHA	Uncertain significance	778737664	RCV001214350;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225675	225675	5:g.225675G>C	-
NM_004168.4(SDHA):c.454G>T (p.Glu152Ter)	6389	SDHA	Pathogenic	778737664	RCV001383931\|RCV002329405;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	225675	225675	225675	-
NM_004168.4(SDHA):c.456G>A (p.Glu152=)	6389	SDHA	Uncertain significance	1579384590	RCV001212300\|RCV003442772\|RCV003473758;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MedGen:C3661900\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	225677	225677	5:g.225677G>A	-
NM_004168.4(SDHA):c.456+1G>A	6389	SDHA	Likely pathogenic	1579384604	RCV001022698\|RCV001204959\|RCV002271609\|RCV002497343;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0031006,MedGen:C5543254,OMIM:619259\|MONDO:MONDO:010	5	225678	225678	5:g.225678G>A	-
NM_004168.4(SDHA):c.456+3G>T	6389	SDHA	Uncertain significance	1362754028	RCV001052520;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225680	225680	5:g.225680G>T	-
NM_004168.4(SDHA):c.456+3_456+4delinsCT	6389	SDHA	Uncertain significance	1734966566	RCV001058233;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225680	225681	NC_000005.9:g.225680_225681delinsCT	-
NM_004168.4(SDHA):c.456+4del	6389	SDHA	Uncertain significance	-1	RCV002898775;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225681	225681	NC_000005.9:g.225681del	-
NM_004168.4(SDHA):c.456+4A>T	6389	SDHA	Uncertain significance	-1	RCV002881498;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225681	225681	NC_000005.9:g.225681A>T	-
NM_004168.4(SDHA):c.456+6G>T	6389	SDHA	Conflicting interpretations of pathogenicity	371735891	RCV000230222\|RCV000662807\|RCV000998344\|RCV002255137\|RCV002518337;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672,	5	225683	225683	5:g.225683G>T	ClinGen:CA3172829	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.456+6G>C	6389	SDHA	Uncertain significance	-1	RCV002872168;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225683	225683	NC_000005.9:g.225683G>C	-
NM_004168.4(SDHA):c.456+8G>A	6389	SDHA	Likely benign	2126547879	RCV002139773;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225685	225685	225685	-
NM_004168.4(SDHA):c.456+9C>T	6389	SDHA	Likely benign	200565489	RCV000436401\|RCV000458063\|RCV000662487;	N	MedGen:CN169374\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225686	225686	5:g.225686C>T	ClinGen:CA3172830	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.456+9C>G	6389	SDHA	Likely benign	200565489	RCV001400748;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225686	225686	225686	-
NM_004168.4(SDHA):c.456+10G>A	6389	SDHA	Benign/Likely benign	781436294	RCV000541963\|RCV002476188;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MedGen:CN169374	5	225687	225687	NC_000005.9:g.225687G>A	ClinGen:CA3172831	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.456+12G>C	6389	SDHA	Uncertain significance	-1	RCV002615462;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225689	225689	NC_000005.9:g.225689G>C	-
NM_004168.4(SDHA):c.456+14G>A	6389	SDHA	Likely benign	-1	RCV002994619;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225691	225691	NC_000005.9:g.225691G>A	-
NM_004168.4(SDHA):c.456+15G>A	6389	SDHA	Likely benign	2126547940	RCV002194891;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225692	225692	225692	-
NM_004168.4(SDHA):c.456+15G>T	6389	SDHA	Likely benign	-1	RCV002870948;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225692	225692	NC_000005.9:g.225692G>T	-
NM_004168.4(SDHA):c.456+16C>T	6389	SDHA	Likely benign	748175384	RCV002106459;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225693	225693	225693	-
NM_004168.4(SDHA):c.456+17T>C	6389	SDHA	Likely benign	1350429949	RCV001965963;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225694	225694	225694	-
NM_004168.4(SDHA):c.456+17T>G	6389	SDHA	Likely benign	-1	RCV002825659;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225694	225694	NC_000005.9:g.225694T>G	-
NM_004168.4(SDHA):c.456+18C>G	6389	SDHA	Likely benign	770457461	RCV001890819;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225695	225695	225695	-
NM_004168.4(SDHA):c.456+19T>C	6389	SDHA	Likely benign	2126547979	RCV002099882;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	225696	225696	225696	-
NM_004168.4(SDHA):c.456+20G>C	6389	SDHA	Benign	193283468	RCV000253864\|RCV001516477\|RCV001528624\|RCV002338802\|RCV003316405;	N	MedGen:CN169374\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C327	5	225697	225697	NC_000005.9:g.225697G>C	ClinGen:CA3172834	CN169374 not specified;
NM_004168.4(SDHA):c.456+20G>A	6389	SDHA	Likely benign	-1	RCV002834306;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225697	225697	NC_000005.9:g.225697G>A	-
NM_004168.4(SDHA):c.456+91G>C	6389	SDHA	Benign	12520059	RCV001544161\|RCV001544162\|RCV001544163;	N	MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0031006,MedGen:C5543254,OMIM:619259	5	225768	225768	225768	-
NM_004168.4(SDHA):c.457-18_457-3dup	6389	SDHA	Likely benign	1421256041	RCV002092961;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225979	225980	225979	-
NM_004168.4(SDHA):c.457-17G>T	6389	SDHA	Likely benign	-1	RCV002966140;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225981	225981	NC_000005.9:g.225981G>T	-
NM_004168.4(SDHA):c.457-12del	6389	SDHA	Benign	2126549133	RCV002156198;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225982	225982	225981	-
NM_004168.4(SDHA):c.457-16T>C	6389	SDHA	Likely benign	371775474	RCV002091923;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	225982	225982	225982	-
NM_004168.4(SDHA):c.457-15T>C	6389	SDHA	Likely benign	-1	RCV002651051;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225983	225983	NC_000005.9:g.225983T>C	-
NM_004168.4(SDHA):c.457-11A>G	6389	SDHA	Likely benign	748265289	RCV002220201;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225987	225987	225987	-
NM_004168.4(SDHA):c.457-9C>T	6389	SDHA	Likely benign	2126549145	RCV002157454;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225989	225989	225989	-
NM_004168.4(SDHA):c.457-4A>G	6389	SDHA	Likely benign	770052391	RCV000554430\|RCV002256390;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	225994	225994	NC_000005.9:g.225994A>G	ClinGen:CA3172853	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.457-4A>T	6389	SDHA	Uncertain significance	-1	RCV002815178;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225994	225994	NC_000005.9:g.225994A>T	-
NM_004168.4(SDHA):c.457-2_457del	6389	SDHA	Pathogenic	878854632	RCV000231881\|RCV001799643\|RCV002338730;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|Human Phenotype Ontology:HP:0100723,MONDO:MONDO:0011719,MeSH:D046152,MedGen:C0238198,OMIM:606764, Orphanet:44890\|MONDO:MONDO:0015	5	225995	225997	NC_000005.9:g.225996_225998del	ClinGen:CA10582418	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.457-2A>G	6389	SDHA	Likely pathogenic	2126549179	RCV001379214;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	225996	225996	225996	-
NM_004168.4(SDHA):c.457-1G>A	6389	SDHA	Pathogenic/Likely pathogenic	-1	RCV002651872\|RCV003336806;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225997	225997	NC_000005.9:g.225997G>A	-
NM_004168.4(SDHA):c.457C>T (p.Leu153=)	6389	SDHA	Conflicting interpretations of pathogenicity	-1	RCV002342190\|RCV003094767;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	225998	225998		-
NM_004168.4(SDHA):c.459A>G (p.Leu153=)	6389	SDHA	Likely benign	2126549200	RCV002101700;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	226000	226000	226000	-
NM_004168.4(SDHA):c.460G>A (p.Glu154Lys)	6389	SDHA	Uncertain significance	1560987595	RCV000699059;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226001	226001	5:g.226001G>A	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.461A>G (p.Glu154Gly)	6389	SDHA	Uncertain significance	777873911	RCV000570801\|RCV000691114;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226002	226002	NC_000005.9:g.226002A>G	ClinGen:CA3172854	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.464A>G (p.Asn155Ser)	6389	SDHA	Uncertain significance	749824479	RCV000530738\|RCV001022840\|RCV002293455\|RCV003476314;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642	5	226005	226005	NC_000005.9:g.226005A>G	ClinGen:CA3172855	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.466T>G (p.Tyr156Asp)	6389	SDHA	Uncertain significance	569384870	RCV000473140\|RCV002244940\|RCV002329085\|RCV002496791;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165	5	226007	226007	NC_000005.9:g.226007T>G	ClinGen:CA16611931	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.467dup (p.Tyr156Ter)	6389	SDHA	Pathogenic	2126549281	RCV001877276;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	226007	226008	226007	-
NM_004168.4(SDHA):c.466T>C (p.Tyr156His)	6389	SDHA	Uncertain significance	-1	RCV002615062;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226007	226007	NC_000005.9:g.226007T>C	-
NM_004168.4(SDHA):c.467A>T (p.Tyr156Phe)	6389	SDHA	Uncertain significance	774589410	RCV001992540;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226008	226008	226008	-
NM_004168.4(SDHA):c.468T>G (p.Tyr156Ter)	6389	SDHA	Pathogenic	989318548	RCV001063216;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226009	226009	5:g.226009T>G	-
NM_004168.4(SDHA):c.468T>C (p.Tyr156=)	6389	SDHA	Likely benign	989318548	RCV001501940;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	226009	226009	226009	-
NM_004168.4(SDHA):c.469G>A (p.Gly157Ser)	6389	SDHA	Uncertain significance	1734987233	RCV001053677;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	226010	226010	5:g.226010G>A	-
NM_004168.4(SDHA):c.471C>T (p.Gly157=)	6389	SDHA	Likely benign	1553997722	RCV000649444\|RCV001022948;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	226012	226012	NC_000005.9:g.226012C>T	ClinGen:CA442691091	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.472A>G (p.Met158Val)	6389	SDHA	Uncertain significance	2126549328	RCV001891357\|RCV003382693;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	226013	226013	226013	-
NM_004168.4(SDHA):c.474G>A (p.Met158Ile)	6389	SDHA	Uncertain significance	-1	RCV003023292;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226015	226015	NC_000005.9:g.226015G>A	-
NM_004168.4(SDHA):c.476C>T (p.Pro159Leu)	6389	SDHA	Uncertain significance	759827541	RCV000219502\|RCV000649409\|RCV003475022;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	226017	226017	5:g.226017C>T	ClinGen:CA3172858	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.477G>A (p.Pro159=)	6389	SDHA	Likely benign	771741537	RCV000538620\|RCV002341428;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	226018	226018	NC_000005.9:g.226018G>A	ClinGen:CA3172859	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.477G>T (p.Pro159=)	6389	SDHA	Likely benign	771741537	RCV000649476\|RCV001023031;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	226018	226018	5:g.226018G>T	ClinGen:CA442691093	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.478T>C (p.Phe160Leu)	6389	SDHA	Uncertain significance	775074528	RCV001921634;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226019	226019	226019	-
NM_004168.4(SDHA):c.480T>G (p.Phe160Leu)	6389	SDHA	Conflicting interpretations of pathogenicity	1060503711	RCV000467274\|RCV000662662\|RCV000853253\|RCV002341056\|RCV003476125;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MON	5	226021	226021	NC_000005.9:g.226021T>G	ClinGen:CA16611826	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.480T>C (p.Phe160=)	6389	SDHA	Likely benign	1060503711	RCV001228166\|RCV003163775;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	226021	226021	5:g.226021T>C	-
NM_004168.4(SDHA):c.482G>A (p.Ser161Asn)	6389	SDHA	Uncertain significance	2126549411	RCV001992127;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226023	226023	226023	-
NM_004168.4(SDHA):c.483C>T (p.Ser161=)	6389	SDHA	Likely benign	2126549418	RCV001490486;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226024	226024	226024	-
NM_004168.4(SDHA):c.484del (p.Arg162fs)	6389	SDHA	Pathogenic/Likely pathogenic	1734988578	RCV001218027\|RCV002497742;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MON	5	226025	226025	5:g.226025_226025del	-
NM_004168.4(SDHA):c.484A>G (p.Arg162Gly)	6389	SDHA	Uncertain significance	1579385526	RCV001986425;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226025	226025	226025	-
NM_004168.4(SDHA):c.485G>C (p.Arg162Thr)	6389	SDHA	Uncertain significance	1579385540	RCV000819046;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226026	226026	5:g.226026G>C	-
NM_004168.4(SDHA):c.486A>G (p.Arg162=)	6389	SDHA	Likely benign	1479127918	RCV000978609\|RCV002337021;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	226027	226027	5:g.226027A>G	-
NM_004168.4(SDHA):c.488C>T (p.Thr163Ile)	6389	SDHA	Uncertain significance	375067326	RCV001326412\|RCV002341676\|RCV003152761;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	226029	226029	226029	-
NM_004168.4(SDHA):c.488C>A (p.Thr163Asn)	6389	SDHA	Uncertain significance	375067326	RCV001970693;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226029	226029	226029	-
NM_004168.4(SDHA):c.492A>G (p.Glu164=)	6389	SDHA	Likely benign	-1	RCV002595811\|RCV003349042;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	226033	226033		-
NM_004168.4(SDHA):c.493G>A (p.Asp165Asn)	6389	SDHA	Uncertain significance	1734989215	RCV001365965\|RCV002341779;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	226034	226034	226034	-
NM_004168.4(SDHA):c.494A>G (p.Asp165Gly)	6389	SDHA	Uncertain significance	1734989377	RCV001219829\|RCV003163694;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MeSH:D030342,MedGen:C0950123	5	226035	226035	5:g.226035A>G	-
NM_004168.4(SDHA):c.494A>T (p.Asp165Val)	6389	SDHA	Uncertain significance	-1	RCV002908062;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226035	226035	NC_000005.9:g.226035A>T	-
NM_004168.4(SDHA):c.496G>A (p.Gly166Arg)	6389	SDHA	Uncertain significance	1060503712	RCV000470736;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226037	226037	NC_000005.9:g.226037G>A	ClinGen:CA16611865	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.497G>A (p.Gly166Glu)	6389	SDHA	Uncertain significance	-1	RCV002609894;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226038	226038	NC_000005.9:g.226038G>A	-
NM_004168.4(SDHA):c.498G>T (p.Gly166=)	6389	SDHA	Uncertain significance	1579385582	RCV000813838;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226039	226039	5:g.226039G>T	-
NM_004168.4(SDHA):c.498G>A (p.Gly166=)	6389	SDHA	Likely benign	-1	RCV002342942\|RCV003096554;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226039	226039		-
NM_004168.4(SDHA):c.499A>C (p.Lys167Gln)	6389	SDHA	Uncertain significance	763578369	RCV000707259\|RCV002334396;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	226040	226040	5:g.226040A>C	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.502A>G (p.Ile168Val)	6389	SDHA	Uncertain significance	1734989945	RCV001325409\|RCV002341675;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	226043	226043	226043	-
NM_004168.4(SDHA):c.503T>C (p.Ile168Thr)	6389	SDHA	Uncertain significance	1553997748	RCV000649435;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226044	226044	5:g.226044T>C	ClinGen:CA359010058	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.505T>C (p.Tyr169His)	6389	SDHA	Uncertain significance	1553997754	RCV000649448\|RCV002334185;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	226046	226046	5:g.226046T>C	ClinGen:CA359010071	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.506A>G (p.Tyr169Cys)	6389	SDHA	Uncertain significance	-1	RCV002335825\|RCV003096600;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226047	226047	226047	-
NM_004168.4(SDHA):c.508C>T (p.Gln170Ter)	6389	SDHA	Pathogenic	1579385645	RCV000823267;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226049	226049	5:g.226049C>T	-
NM_004168.4(SDHA):c.508C>A (p.Gln170Lys)	6389	SDHA	Uncertain significance	1579385645	RCV002023950;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226049	226049	226049	-
NM_004168.4(SDHA):c.509A>T (p.Gln170Leu)	6389	SDHA	Uncertain significance	2126549625	RCV002008912;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	226050	226050	226050	-
NM_004168.4(SDHA):c.510G>C (p.Gln170His)	6389	SDHA	Uncertain significance	1579385651	RCV000820842\|RCV002257988;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	226051	226051	5:g.226051G>C	-
NM_004168.4(SDHA):c.511C>T (p.Arg171Cys)	6389	SDHA	Uncertain significance	776193478	RCV001237617\|RCV001799748\|RCV002563895;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|Human Phenotype Ontology:HP:0100723,MONDO:MONDO:0011719,MeSH:D046152,MedGen:C0238198,OMIM:606764, Orphanet:44890\|MeSH:D030342,Med	5	226052	226052	5:g.226052C>T	-
NM_004168.4(SDHA):c.512G>A (p.Arg171His)	6389	SDHA	Uncertain significance	587782076	RCV000130572\|RCV000466700\|RCV000512840\|RCV001153308\|RCV001153309\|RCV001153307\|RCV001799623\|RCV003474764;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MedGen:C3661900\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000	5	226053	226053	5:g.226053G>A	ClinGen:CA166671	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.512G>C (p.Arg171Pro)	6389	SDHA	Uncertain significance	-1	RCV002344218\|RCV003096626;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226053	226053	226053	-
NM_004168.4(SDHA):c.513T>C (p.Arg171=)	6389	SDHA	Benign/Likely benign	765157205	RCV000226781\|RCV000412315\|RCV000441092\|RCV001023603;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MedGen:CN169374\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672,	5	226054	226054	NC_000005.9:g.226054T>C	ClinGen:CA3172864	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.513T>A (p.Arg171=)	6389	SDHA	Likely benign	-1	RCV002889357;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226054	226054		-
NM_004168.4(SDHA):c.514G>A (p.Ala172Thr)	6389	SDHA	Uncertain significance	1734991441	RCV001214432;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226055	226055	5:g.226055G>A	-
NM_004168.4(SDHA):c.515C>T (p.Ala172Val)	6389	SDHA	Uncertain significance	1734991593	RCV001933975;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	226056	226056	226056	-
NM_004168.4(SDHA):c.515C>A (p.Ala172Glu)	6389	SDHA	Uncertain significance	-1	RCV002299585;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226056	226056	226056	-
NM_004168.4(SDHA):c.516A>G (p.Ala172=)	6389	SDHA	Likely benign	181278759	RCV000464972\|RCV000572674;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	226057	226057	NC_000005.9:g.226057A>G	ClinGen:CA3172865	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.523G>A (p.Gly175Arg)	6389	SDHA	Uncertain significance	753004001	RCV000801943\|RCV002336612;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	226064	226064	5:g.226064G>A	-
NM_004168.4(SDHA):c.523G>C (p.Gly175Arg)	6389	SDHA	Uncertain significance	753004001	RCV001023787\|RCV001337582;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226064	226064	5:g.226064G>C	-
NM_004168.4(SDHA):c.525A>G (p.Gly175=)	6389	SDHA	Likely benign	2126549734	RCV001469556;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226066	226066	226066	-
NM_004168.4(SDHA):c.528G>C (p.Gln176His)	6389	SDHA	Uncertain significance	769454045	RCV001364421;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226069	226069	226069	-
NM_004168.4(SDHA):c.530G>C (p.Ser177Thr)	6389	SDHA	Uncertain significance	1553997783	RCV000649441\|RCV002343343;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	226071	226071	5:g.226071G>C	ClinGen:CA359010226	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.530G>A (p.Ser177Asn)	6389	SDHA	Uncertain significance	1553997783	RCV001296741\|RCV002350524;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	226071	226071	226071	-
NM_004168.4(SDHA):c.530G>T (p.Ser177Ile)	6389	SDHA	Uncertain significance	-1	RCV002653811;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226071	226071	NC_000005.9:g.226071G>T	-
NM_004168.4(SDHA):c.531C>G (p.Ser177Arg)	6389	SDHA	Uncertain significance	-1	RCV002615281;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226072	226072	NC_000005.9:g.226072C>G	-
NM_004168.4(SDHA):c.534C>T (p.Leu178=)	6389	SDHA	Likely benign	749329370	RCV000229841\|RCV002347888;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	226075	226075	5:g.226075C>T	ClinGen:CA3172871	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.537G>A (p.Lys179=)	6389	SDHA	Likely benign	1207914111	RCV000938432\|RCV002346131;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	226078	226078	5:g.226078G>A	-
NM_004168.4(SDHA):c.540T>C (p.Phe180=)	6389	SDHA	Likely benign	2126549842	RCV001499962;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	226081	226081	226081	-
NM_004168.4(SDHA):c.541G>C (p.Gly181Arg)	6389	SDHA	Uncertain significance	1305547879	RCV002009805\|RCV003170333;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	226082	226082	226082	-
NM_004168.4(SDHA):c.545A>G (p.Lys182Arg)	6389	SDHA	Uncertain significance	-1	RCV002644218;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226086	226086	NC_000005.9:g.226086A>G	-
NM_004168.4(SDHA):c.546G>A (p.Lys182=)	6389	SDHA	Likely benign	757707693	RCV000649488\|RCV002343346;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	226087	226087	5:g.226087G>A	ClinGen:CA3172873	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.548G>A (p.Gly183Asp)	6389	SDHA	Uncertain significance	1734993975	RCV001219211;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226089	226089	5:g.226089G>A	-
NM_004168.4(SDHA):c.549C>T (p.Gly183=)	6389	SDHA	Conflicting interpretations of pathogenicity	61733344	RCV000239367\|RCV000291747\|RCV000339713\|RCV000394814\|RCV000418051\|RCV000571465\|RCV001800618\|RCV003316320;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506\|MONDO:MONDO:0017366,MedGen:C1708353, Orphanet:29072\|MONDO:MONDO:0100	5	226090	226090	NC_000005.9:g.226090C>T	ClinGen:CA3172874	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.550G>A (p.Gly184Arg)	6389	SDHA	Benign/Likely benign	148246073	RCV000343277\|RCV000304507\|RCV000390055\|RCV000514856\|RCV000575599\|RCV000607544\|RCV001080182\|RCV003316148;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0017366,MedGen:C1708353, Orphanet:29072\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:14016	5	226091	226091	NC_000005.9:g.226091G>A	ClinGen:CA348484	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.551G>C (p.Gly184Ala)	6389	SDHA	Uncertain significance	1579385819	RCV001024215\|RCV001369871;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226092	226092	5:g.226092G>C	-
NM_004168.4(SDHA):c.551G>A (p.Gly184Glu)	6389	SDHA	Uncertain significance	1579385819	RCV001305199\|RCV003135944\|RCV003294234;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	226092	226092	226092	-
NM_004168.4(SDHA):c.552G>A (p.Gly184=)	6389	SDHA	Likely benign	147444427	RCV000871614\|RCV002346006;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	226093	226093	5:g.226093G>A	-
NM_004168.4(SDHA):c.553C>T (p.Gln185Ter)	6389	SDHA	Pathogenic	775827529	RCV000575535\|RCV000702668\|RCV003159959\|RCV003476321;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MedGen:C3661900\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642	5	226094	226094	5:g.226094C>T	ClinGen:CA3172876	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.553C>G (p.Gln185Glu)	6389	SDHA	Uncertain significance	775827529	RCV001024247\|RCV001070085\|RCV003473597;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	226094	226094	5:g.226094C>G	-
NM_004168.4(SDHA):c.554dup (p.Ala186fs)	6389	SDHA	Pathogenic/Likely pathogenic	1173940446	RCV001384161\|RCV002350731\|RCV003132489;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	5	226094	226095	226094	-
NM_004168.4(SDHA):c.556G>T (p.Ala186Ser)	6389	SDHA	Uncertain significance	-1	RCV002815599\|RCV003274043;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	226097	226097	NC_000005.9:g.226097G>T	-
NM_004168.4(SDHA):c.557C>T (p.Ala186Val)	6389	SDHA	Uncertain significance	2126550013	RCV001981081\|RCV002346254;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	226098	226098	226098	-
NM_004168.4(SDHA):c.558C>T (p.Ala186=)	6389	SDHA	Conflicting interpretations of pathogenicity	199618059	RCV000649483\|RCV001155907\|RCV001155908\|RCV001155909\|RCV002343344;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0017366,MedGen:C1708353, Orphanet:29072\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:000	5	226099	226099	NC_000005.9:g.226099C>T	ClinGen:CA3172877	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.559C>T (p.His187Tyr)	6389	SDHA	Uncertain significance	1579385898	RCV000801803\|RCV002507389;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO	5	226100	226100	5:g.226100C>T	-
NM_004168.4(SDHA):c.560A>G (p.His187Arg)	6389	SDHA	Uncertain significance	1236616384	RCV001303050;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226101	226101	226101	-
NM_004168.4(SDHA):c.562C>T (p.Arg188Trp)	6389	SDHA	Likely pathogenic	553257776	RCV000555353\|RCV000571189\|RCV003335474;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226103	226103	NC_000005.9:g.226103C>T	ClinGen:CA3172879	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.562C>A (p.Arg188=)	6389	SDHA	Likely benign	553257776	RCV001437405;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226103	226103	226103	-
NM_004168.4(SDHA):c.563G>A (p.Arg188Gln)	6389	SDHA	Conflicting interpretations of pathogenicity	139881415	RCV000518854\|RCV000531381\|RCV001024356\|RCV003335449\|RCV003330742;	N	MedGen:C3661900\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165	5	226104	226104	5:g.226104G>A	ClinGen:CA3172880	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.564G>A (p.Arg188=)	6389	SDHA	Likely benign	1579385933	RCV001024366\|RCV001493597;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226105	226105	5:g.226105G>A	-
NM_004168.4(SDHA):c.565T>C (p.Cys189Arg)	6389	SDHA	Uncertain significance	1734996495	RCV001309048;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226106	226106	226106	-
NM_004168.4(SDHA):c.568T>C (p.Cys190Arg)	6389	SDHA	Uncertain significance	908267345	RCV001043245\|RCV002258097;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	226109	226109	5:g.226109T>C	-
NM_004168.4(SDHA):c.568T>A (p.Cys190Ser)	6389	SDHA	Uncertain significance	908267345	RCV002023582;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226109	226109	226109	-
NM_004168.4(SDHA):c.570C>T (p.Cys190=)	6389	SDHA	Likely benign	1060505008	RCV001394415\|RCV002350047;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	226111	226111	NC_000005.9:g.226111C>T	ClinGen:CA16611936	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.571T>C (p.Cys191Arg)	6389	SDHA	Uncertain significance	2126550176	RCV001972911;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226112	226112	226112	-
NM_004168.4(SDHA):c.572G>A (p.Cys191Tyr)	6389	SDHA	Uncertain significance	1393298155	RCV001339874\|RCV003169607;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	226113	226113	226113	-
NM_004168.4(SDHA):c.572G>C (p.Cys191Ser)	6389	SDHA	Uncertain significance	1393298155	RCV001373494\|RCV003473889;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	226113	226113	226113	-
NM_004168.4(SDHA):c.573T>C (p.Cys191=)	6389	SDHA	Likely benign	765111856	RCV000940696\|RCV001024470;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	226114	226114	5:g.226114T>C	-
NM_004168.4(SDHA):c.578C>G (p.Ala193Gly)	6389	SDHA	Uncertain significance	1734997662	RCV001040886;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	226119	226119	5:g.226119C>G	-
NM_004168.4(SDHA):c.578C>T (p.Ala193Val)	6389	SDHA	Uncertain significance	1734997662	RCV001036295;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	226119	226119	5:g.226119C>T	-
NM_004168.4(SDHA):c.582T>C (p.Asp194=)	6389	SDHA	Likely benign	-1	RCV002917946;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226123	226123		-
NM_004168.4(SDHA):c.583C>T (p.Arg195Trp)	6389	SDHA	Uncertain significance	1337777456	RCV001060414\|RCV001157610\|RCV001157611\|RCV001155910\|RCV003473672;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506\|MONDO	5	226124	226124	5:g.226124C>T	-
NM_004168.4(SDHA):c.583C>G (p.Arg195Gly)	6389	SDHA	Uncertain significance	1337777456	RCV002018269;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226124	226124	226124	-
NM_004168.4(SDHA):c.584G>A (p.Arg195Gln)	6389	SDHA	Uncertain significance	762956849	RCV000544157\|RCV002358584\|RCV002491086;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072;	5	226125	226125	NC_000005.9:g.226125G>A	ClinGen:CA3172883	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.585G>C (p.Arg195=)	6389	SDHA	Likely benign	766339992	RCV000868956\|RCV001024612\|RCV002501285;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; M	5	226126	226126	5:g.226126G>C	-
NM_004168.4(SDHA):c.585G>A (p.Arg195=)	6389	SDHA	Likely benign	766339992	RCV001414234;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226126	226126	226126	-
NM_004168.4(SDHA):c.586A>G (p.Thr196Ala)	6389	SDHA	Uncertain significance	-1	RCV002717387;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226127	226127	NC_000005.9:g.226127A>G	-
NM_004168.4(SDHA):c.587C>T (p.Thr196Ile)	6389	SDHA	Uncertain significance	1560987863	RCV000698681;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226128	226128	5:g.226128C>T	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.588T>C (p.Thr196=)	6389	SDHA	Likely benign	1278276778	RCV001463741\|RCV002359034;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	226129	226129	226129	-
NM_004168.4(SDHA):c.589G>C (p.Gly197Arg)	6389	SDHA	Uncertain significance	1560987881	RCV000692173;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226130	226130	NC_000005.9:g.226130G>C	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.589G>A (p.Gly197Ser)	6389	SDHA	Uncertain significance	1560987881	RCV001909660;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226130	226130	226130	-
NM_004168.4(SDHA):c.590G>A (p.Gly197Asp)	6389	SDHA	Uncertain significance	1579386052	RCV000797002;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226131	226131	5:g.226131G>A	-
NM_004168.4(SDHA):c.591C>G (p.Gly197=)	6389	SDHA	Likely benign	-1	RCV002889464;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226132	226132		-
NM_004168.4(SDHA):c.594C>T (p.His198=)	6389	SDHA	Likely benign	1579386061	RCV001409537\|RCV002258054;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	226135	226135	5:g.226135C>T	-
NM_004168.4(SDHA):c.595T>A (p.Ser199Thr)	6389	SDHA	Uncertain significance	770407681	RCV000800619\|RCV001024725\|RCV003472363;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	226136	226136	5:g.226136T>A	-
NM_004168.4(SDHA):c.596C>T (p.Ser199Leu)	6389	SDHA	Uncertain significance	878854633	RCV000232616\|RCV002354654;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	226137	226137	5:g.226137C>T	ClinGen:CA10582419	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.597G>A (p.Ser199=)	6389	SDHA	Benign/Likely benign	141874250	RCV000469362\|RCV000569336;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	226138	226138	NC_000005.9:g.226138G>A	ClinGen:CA3172886	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.597G>T (p.Ser199=)	6389	SDHA	Likely benign	141874250	RCV001432038;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226138	226138	226138	-
NM_004168.4(SDHA):c.598C>T (p.Leu200=)	6389	SDHA	Likely benign	764307917	RCV000475350\|RCV000568755;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	226139	226139	NC_000005.9:g.226139C>T	ClinGen:CA3172887	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.598C>A (p.Leu200Ile)	6389	SDHA	Uncertain significance	764307917	RCV001945888\|RCV003167297\|RCV003475179;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	226139	226139	226139	-
NM_004168.4(SDHA):c.600A>G (p.Leu200=)	6389	SDHA	Benign/Likely benign	201967413	RCV000239373\|RCV000572465\|RCV002479952;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN169374	5	226141	226141	NC_000005.9:g.226141A>G	ClinGen:CA3172888	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.602T>C (p.Leu201Ser)	6389	SDHA	Uncertain significance	150646390	RCV001058277;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226143	226143	5:g.226143T>C	-
NM_004168.4(SDHA):c.603G>A (p.Leu201=)	6389	SDHA	Likely benign	2126550482	RCV001483727\|RCV002359087;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	226144	226144	226144	-
NM_004168.4(SDHA):c.607A>G (p.Thr203Ala)	6389	SDHA	Uncertain significance	373340696	RCV000458356\|RCV000575357\|RCV002481480\|RCV003128946\|RCV003476123;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; M	5	226148	226148	NC_000005.9:g.226148A>G	ClinGen:CA3172890	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.608C>T (p.Thr203Ile)	6389	SDHA	Uncertain significance	1735001122	RCV001218178\|RCV003473769;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	226149	226149	5:g.226149C>T	-
NM_004168.4(SDHA):c.608C>G (p.Thr203Ser)	6389	SDHA	Uncertain significance	1735001122	RCV001879242;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226149	226149	226149	-
NM_004168.4(SDHA):c.612A>G (p.Leu204=)	6389	SDHA	Likely benign	1735001336	RCV001864725;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	226153	226153	226153	-
NM_004168.4(SDHA):c.613T>C (p.Tyr205His)	6389	SDHA	Uncertain significance	61754481	RCV000471598\|RCV000575607\|RCV000764602\|RCV001848822\|RCV003476119;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506; MO	5	226154	226154	NC_000005.9:g.226154T>C	ClinGen:CA3172891	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.615T>A (p.Tyr205Ter)	6389	SDHA	Pathogenic	876658486	RCV000221025\|RCV000798190\|RCV003316203;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226156	226156	NC_000005.9:g.226156T>A	ClinGen:CA10578627	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.615T>C (p.Tyr205=)	6389	SDHA	Likely benign	876658486	RCV002202864;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	226156	226156	226156	-
NM_004168.4(SDHA):c.619A>C (p.Arg207=)	6389	SDHA	Benign	6555055	RCV000118319\|RCV000162480\|RCV000298743\|RCV000263653\|RCV000355926\|RCV001509668\|RCV001705862\|RCV003315683;	N	MedGen:CN169374\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0017366,MedGen:C1708353, Orphanet:2907	5	226160	226160	5:g.226160A>C	ClinGen:CA155156	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.619_620delinsC (p.Ser208fs)	6389	SDHA	Pathogenic	1579386206	RCV000818060;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226160	226161	5:g.226161_226161del	-
NM_004168.4(SDHA):c.619A>T (p.Arg207Trp)	6389	SDHA	Uncertain significance	6555055	RCV001046070;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	226160	226160	5:g.226160A>T	-
NM_004168.4(SDHA):c.619A>G (p.Arg207Gly)	6389	SDHA	Uncertain significance	6555055	RCV001301154;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226160	226160	226160	-
NM_004168.4(SDHA):c.619_620delinsCA (p.Arg207Gln)	6389	SDHA	Uncertain significance	2126550631	RCV001890610\|RCV002359349;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	226160	226161	226160	-
NM_004168.4(SDHA):c.620G>A (p.Arg207Lys)	6389	SDHA	Uncertain significance	780411478	RCV001202794\|RCV003163526;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	226161	226161	5:g.226161G>A	-
NM_004168.4(SDHA):c.620G>C (p.Arg207Thr)	6389	SDHA	Uncertain significance	780411478	RCV001242941;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226161	226161	5:g.226161G>C	-
NM_004168.4(SDHA):c.621G>A (p.Arg207=)	6389	SDHA	Uncertain significance	2126550683	RCV001906920;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	226162	226162	226162	-
NM_004168.4(SDHA):c.621+1G>A	6389	SDHA	Likely pathogenic	1735002961	RCV001050872;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	226163	226163	5:g.226163G>A	-
NM_004168.4(SDHA):c.621+8C>T	6389	SDHA	Likely benign	201091275	RCV000227518;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226170	226170	5:g.226170C>T	ClinGen:CA3172893	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.621+9G>A	6389	SDHA	Likely benign	1060505005	RCV000470380;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226171	226171	NC_000005.9:g.226171G>A	ClinGen:CA16612052	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.621+9G>C	6389	SDHA	Likely benign	-1	RCV002780364;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226171	226171	NC_000005.9:g.226171G>C	-
NM_004168.4(SDHA):c.621+10C>T	6389	SDHA	Likely benign	1458669735	RCV001481386;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	226172	226172	226172	-
NM_004168.4(SDHA):c.621+11C>A	6389	SDHA	Likely benign	2126550755	RCV002176189;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226173	226173	226173	-
NM_004168.4(SDHA):c.621+11C>T	6389	SDHA	Likely benign	-1	RCV002953299;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226173	226173	NC_000005.9:g.226173C>T	-
NM_004168.4(SDHA):c.621+12C>T	6389	SDHA	Likely benign	-1	RCV003110248;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	226174	226174	NC_000005.9:g.226174C>T	-
NM_004168.4(SDHA):c.621+13C>T	6389	SDHA	Likely benign	2126550780	RCV002156100;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226175	226175	226175	-
NM_004168.4(SDHA):c.621+14C>T	6389	SDHA	Likely benign	776301796	RCV002139995;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	226176	226176	226176	-
NM_004168.4(SDHA):c.621+15G>A	6389	SDHA	Likely benign	747737117	RCV002196836;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	226177	226177	226177	-
NM_004168.4(SDHA):c.621+15G>T	6389	SDHA	Likely benign	-1	RCV002894395;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226177	226177	NC_000005.9:g.226177G>T	-
NM_004168.4(SDHA):c.621+16T>C	6389	SDHA	Likely benign	769390635	RCV000613395\|RCV002063187;	N	MedGen:CN169374\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	226178	226178	5:g.226178T>C	ClinGen:CA3172897	CN169374 not specified;
NM_004168.4(SDHA):c.621+17C>T	6389	SDHA	Likely benign	2126550811	RCV002195398;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	226179	226179	226179	-
NM_004168.4(SDHA):c.621+18C>T	6389	SDHA	Likely benign	1735004595	RCV002074489;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	226180	226180	226180	-
NM_004168.4(SDHA):c.621+18C>G	6389	SDHA	Likely benign	-1	RCV002770699;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226180	226180	NC_000005.9:g.226180C>G	-
NM_004168.4(SDHA):c.621+19A>T	6389	SDHA	Likely benign	772849135	RCV002167508;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226181	226181	226181	-
NM_004168.4(SDHA):c.621+19A>G	6389	SDHA	Likely benign	772849135	RCV002139657;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	226181	226181	226181	-
NM_004168.4(SDHA):c.621+20C>T	6389	SDHA	Likely benign	-1	RCV002895260;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	226182	226182	NC_000005.9:g.226182C>T	-
NM_004168.4(SDHA):c.622-7_622-4del	6389	SDHA	Likely benign	2126557982	RCV001456681;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	228289	228292	228288	-
NM_004168.4(SDHA):c.622-8del	6389	SDHA	Likely benign	777777373	RCV000908417;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	228290	228290	5:g.228290_228290del	-
NM_004168.4(SDHA):c.622-8T>C	6389	SDHA	Conflicting interpretations of pathogenicity	370714378	RCV000233358\|RCV000411772\|RCV000427201;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MedGen:C3661900	5	228292	228292	5:g.228292T>C	ClinGen:CA3172923	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.622-7C>T	6389	SDHA	Likely benign	759371428	RCV000951952\|RCV000987494;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	228293	228293	5:g.228293C>T	-
NM_004168.4(SDHA):c.622-5T>C	6389	SDHA	Conflicting interpretations of pathogenicity	878854634	RCV000229170\|RCV000569503;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	228295	228295	NC_000005.9:g.228295T>C	ClinGen:CA10582420	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.622-4T>C	6389	SDHA	Conflicting interpretations of pathogenicity	1579390820	RCV000884513\|RCV002363325;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	228296	228296	5:g.228296T>C	-
NM_004168.4(SDHA):c.622-1G>A	6389	SDHA	Likely pathogenic	1285132774	RCV000649416;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	228299	228299	NC_000005.9:g.228299G>A	ClinGen:CA359010778	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.622T>C (p.Ser208Pro)	6389	SDHA	Uncertain significance	-1	RCV003079058;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	228300	228300	NC_000005.9:g.228300T>C	-
NM_004168.4(SDHA):c.625C>G (p.Leu209Val)	6389	SDHA	Uncertain significance	-1	RCV002838706;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	228303	228303	NC_000005.9:g.228303C>G	-
NM_004168.4(SDHA):c.626T>C (p.Leu209Pro)	6389	SDHA	Uncertain significance	1579390858	RCV001025064\|RCV001369092;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	228304	228304	5:g.228304T>C	-
NM_004168.4(SDHA):c.627G>A (p.Leu209=)	6389	SDHA	Likely benign	149821224	RCV000458176\|RCV002367620;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	228305	228305	NC_000005.9:g.228305G>A	ClinGen:CA3172925	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.628C>T (p.Arg210Ter)	6389	SDHA	Pathogenic/Likely pathogenic	775143272	RCV000649430\|RCV001025088\|RCV001799694\|RCV003472044;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|Human Phenotype Ontology:HP:0100723,MONDO:MONDO:0011719,MeSH:D0	5	228306	228306	NC_000005.9:g.228306C>T	ClinGen:CA3172926	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.629G>A (p.Arg210Gln)	6389	SDHA	Uncertain significance	762108779	RCV000687867\|RCV001025100;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	228307	228307	NC_000005.9:g.228307G>A	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.630A>G (p.Arg210=)	6389	SDHA	Conflicting interpretations of pathogenicity	1579390913	RCV001025116\|RCV001045034;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	228308	228308	5:g.228308A>G	-
NM_004168.4(SDHA):c.630A>T (p.Arg210=)	6389	SDHA	Likely benign	1579390913	RCV001418168\|RCV002368310;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	228308	228308	228308	-
NM_004168.4(SDHA):c.632A>G (p.Tyr211Cys)	6389	SDHA	Uncertain significance	1235961098	RCV000793019\|RCV002360914;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	228310	228310	5:g.228310A>G	-
NM_004168.4(SDHA):c.632A>T (p.Tyr211Phe)	6389	SDHA	Uncertain significance	1235961098	RCV001224819\|RCV002366013;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	228310	228310	5:g.228310A>T	-
NM_004168.4(SDHA):c.633T>G (p.Tyr211Ter)	6389	SDHA	Pathogenic	1307665893	RCV002037896\|RCV002361297;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	228311	228311	228311	-
NM_004168.4(SDHA):c.633T>C (p.Tyr211=)	6389	SDHA	Likely benign	1307665893	RCV002167974\|RCV002361434;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	228311	228311	228311	-
NM_004168.4(SDHA):c.635A>G (p.Asp212Gly)	6389	SDHA	Uncertain significance	750531440	RCV001217329;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	228313	228313	5:g.228313A>G	-
NM_004168.4(SDHA):c.638C>A (p.Thr213Asn)	6389	SDHA	Uncertain significance	766421069	RCV000472577;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	228316	228316	NC_000005.9:g.228316C>A	ClinGen:CA16611866	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.638C>T (p.Thr213Ile)	6389	SDHA	Uncertain significance	766421069	RCV001236994;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	228316	228316	5:g.228316C>T	-
NM_004168.4(SDHA):c.640A>G (p.Ser214Gly)	6389	SDHA	Uncertain significance	752144637	RCV000706981\|RCV002360833;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	228318	228318	NC_000005.9:g.228318A>G	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.641G>A (p.Ser214Asn)	6389	SDHA	Uncertain significance	755432673	RCV000571276\|RCV001044490;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	228319	228319	5:g.228319G>A	ClinGen:CA3172933	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.644_645del (p.Tyr215fs)	6389	SDHA	Pathogenic	1560989804	RCV000690156;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	228321	228322	NC_000005.9:g.228322_228323del	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.644A>G (p.Tyr215Cys)	6389	SDHA	Uncertain significance	781660628	RCV000808922\|RCV002363084;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	228322	228322	5:g.228322A>G	-
NM_004168.4(SDHA):c.645T>C (p.Tyr215=)	6389	SDHA	Likely benign	-1	RCV002361895\|RCV003098256;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	228323	228323		-
NM_004168.4(SDHA):c.646T>C (p.Phe216Leu)	6389	SDHA	Uncertain significance	1735162987	RCV001212719;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	228324	228324	5:g.228324T>C	-
NM_004168.4(SDHA):c.649G>C (p.Val217Leu)	6389	SDHA	Uncertain significance	1735163272	RCV001039092;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	228327	228327	5:g.228327G>C	-
NM_004168.4(SDHA):c.653A>T (p.Glu218Val)	6389	SDHA	Uncertain significance	1735163544	RCV001218571;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	228331	228331	5:g.228331A>T	-
NM_004168.4(SDHA):c.654G>T (p.Glu218Asp)	6389	SDHA	Uncertain significance	-1	RCV002301576;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	228332	228332	228332	-
NM_004168.4(SDHA):c.662C>G (p.Ala221Gly)	6389	SDHA	Uncertain significance	1735163984	RCV001340648;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	228340	228340	228340	-
NM_004168.4(SDHA):c.663C>T (p.Ala221=)	6389	SDHA	Likely benign	1579391069	RCV001418916\|RCV003307727;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	228341	228341	5:g.228341C>T	-
NM_004168.4(SDHA):c.663C>G (p.Ala221=)	6389	SDHA	Likely benign	1579391069	RCV002207092;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	228341	228341	228341	-
NM_004168.4(SDHA):c.664T>G (p.Leu222Val)	6389	SDHA	Uncertain significance	1553998191	RCV000545927\|RCV002367927;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	228342	228342	NC_000005.9:g.228342T>G	ClinGen:CA359010887	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.665T>C (p.Leu222Ser)	6389	SDHA	Uncertain significance	-1	RCV002997031;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	228343	228343	NC_000005.9:g.228343T>C	-
NM_004168.4(SDHA):c.667del (p.Asp223fs)	6389	SDHA	Pathogenic/Likely pathogenic	587782077	RCV000130573\|RCV000527052\|RCV001008075\|RCV003474765;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MedGen:C3661900\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642	5	228344	228344	5:g.228344_228344del	ClinGen:CA166673	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.666G>T (p.Leu222Phe)	6389	SDHA	Uncertain significance	778256616	RCV000463550\|RCV002293444;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MedGen:CN517202	5	228344	228344	NC_000005.9:g.228344G>T	ClinGen:CA3172940	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.667G>T (p.Asp223Tyr)	6389	SDHA	Uncertain significance	1579391108	RCV000795749;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	228345	228345	5:g.228345G>T	-
NM_004168.4(SDHA):c.667G>C (p.Asp223His)	6389	SDHA	Uncertain significance	1579391108	RCV001025527\|RCV001341508;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	228345	228345	5:g.228345G>C	-
NM_004168.4(SDHA):c.668A>C (p.Asp223Ala)	6389	SDHA	Uncertain significance	2126558436	RCV002030099\|RCV003164013;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	228346	228346	228346	-
NM_004168.4(SDHA):c.670C>T (p.Leu224Phe)	6389	SDHA	Uncertain significance	-1	RCV002367197\|RCV003103323\|RCV003475354;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	228348	228348	228348	-
NM_004168.4(SDHA):c.672C>T (p.Leu224=)	6389	SDHA	Likely benign	2126558458	RCV001426749;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	228350	228350	228350	-
NM_004168.4(SDHA):c.673C>T (p.Leu225=)	6389	SDHA	Likely benign	1579391116	RCV000924942\|RCV002372570;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	228351	228351	5:g.228351C>T	-
NM_004168.4(SDHA):c.674T>C (p.Leu225Pro)	6389	SDHA	Uncertain significance	2126558482	RCV001995465;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	228352	228352	228352	-
NM_004168.4(SDHA):c.675G>C (p.Leu225=)	6389	SDHA	Likely benign	1367248054	RCV000925912\|RCV002372572;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	228353	228353	5:g.228353G>C	-
NM_004168.4(SDHA):c.675G>A (p.Leu225=)	6389	SDHA	Likely benign	1367248054	RCV001025621\|RCV001395754;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	228353	228353	5:g.228353G>A	-
NM_004168.4(SDHA):c.676A>T (p.Met226Leu)	6389	SDHA	Uncertain significance	1579391135	RCV000796563;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	228354	228354	5:g.228354A>T	-
NM_004168.4(SDHA):c.677T>C (p.Met226Thr)	6389	SDHA	Uncertain significance	1735165932	RCV001299483;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	228355	228355	228355	-
NM_004168.4(SDHA):c.677T>A (p.Met226Lys)	6389	SDHA	Uncertain significance	-1	RCV002993816;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	228355	228355	NC_000005.9:g.228355T>A	-
NM_004168.4(SDHA):c.678G>A (p.Met226Ile)	6389	SDHA	Uncertain significance	745884899	RCV000687038;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	228356	228356	NC_000005.9:g.228356G>A	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.682A>T (p.Asn228Tyr)	6389	SDHA	Uncertain significance	2126558556	RCV001908935;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	228360	228360	228360	-
NM_004168.4(SDHA):c.683A>G (p.Asn228Ser)	6389	SDHA	Uncertain significance	2126558564	RCV001894346\|RCV002256852;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	228361	228361	228361	-
NM_004168.4(SDHA):c.684T>C (p.Asn228=)	6389	SDHA	Benign	2115272	RCV000118320\|RCV000162481\|RCV000311792\|RCV000276689\|RCV000368927\|RCV001705863\|RCV001509669\|RCV003315684;	N	MedGen:CN169374\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0017366,MedGen:C1708353, Orphanet:29072\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:50	5	228362	228362	5:g.228362T>C	ClinGen:CA155158	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.688del (p.Glu230fs)	6389	SDHA	Pathogenic/Likely pathogenic	1553998199	RCV000551986\|RCV000566076\|RCV000853371\|RCV001783056\|RCV002491084\|RCV003476305;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|	5	228363	228363	NC_000005.9:g.228366del	ClinGen:CA658657421	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.687G>A (p.Gly229=)	6389	SDHA	Likely benign	775359678	RCV000865278\|RCV002372419;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	228365	228365	5:g.228365G>A	-
NM_004168.4(SDHA):c.687G>C (p.Gly229=)	6389	SDHA	Likely benign	775359678	RCV001495131;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	228365	228365	228365	-
NM_004168.4(SDHA):c.688G>C (p.Glu230Gln)	6389	SDHA	Uncertain significance	1436777353	RCV000649449\|RCV002369739\|RCV003472046;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	228366	228366	NC_000005.9:g.228366G>C	ClinGen:CA359010941	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.688G>A (p.Glu230Lys)	6389	SDHA	Uncertain significance	-1	RCV002942789\|RCV003308357;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	228366	228366	NC_000005.9:g.228366G>A	-
NM_004168.4(SDHA):c.693C>T (p.Cys231=)	6389	SDHA	Likely benign	-1	RCV003082552;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	228371	228371		-
NM_004168.4(SDHA):c.694C>T (p.Arg232Cys)	6389	SDHA	Uncertain significance	878854635	RCV000231015\|RCV000764603\|RCV001025834\|RCV003329265;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO	5	228372	228372	NC_000005.9:g.228372C>T	ClinGen:CA10582421	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.695G>A (p.Arg232His)	6389	SDHA	Uncertain significance	1060503708	RCV000473347\|RCV001025841;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	228373	228373	NC_000005.9:g.228373G>A	ClinGen:CA16611867	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.696T>G (p.Arg232=)	6389	SDHA	Likely benign	-1	RCV002848397;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	228374	228374		-
NM_004168.4(SDHA):c.697G>A (p.Gly233Ser)	6389	SDHA	Uncertain significance	2126558729	RCV001976993\|RCV003170418;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	228375	228375	228375	-
NM_004168.4(SDHA):c.698G>T (p.Gly233Val)	6389	SDHA	Uncertain significance	878854636	RCV000233811\|RCV001799644\|RCV002372275;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|Human Phenotype Ontology:HP:0100723,MONDO:MONDO:0011719,MeSH:D046152,MedGen:C0238198,OMIM:606764, Orphanet:44890\|MONDO:MONDO:0015	5	228376	228376	5:g.228376G>T	ClinGen:CA10582422	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.698G>A (p.Gly233Asp)	6389	SDHA	Uncertain significance	878854636	RCV001991733;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	228376	228376	228376	-
NM_004168.4(SDHA):c.699del (p.Val234fs)	6389	SDHA	Pathogenic	1175771583	RCV001240188;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	228377	228377	5:g.228377_228377del	-
NM_004168.4(SDHA):c.700G>A (p.Val234Ile)	6389	SDHA	Uncertain significance	2126558764	RCV001952662;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	228378	228378	228378	-
NM_004168.4(SDHA):c.702C>T (p.Val234=)	6389	SDHA	Likely benign	1205748459	RCV002097689;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	228380	228380	228380	-
NM_004168.4(SDHA):c.704T>C (p.Ile235Thr)	6389	SDHA	Uncertain significance	144513891	RCV000203953\|RCV000410184\|RCV000562815\|RCV001197548\|RCV001582713\|RCV002478742;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|	5	228382	228382	5:g.228382T>C	ClinGen:CA348232	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.705C>T (p.Ile235=)	6389	SDHA	Likely benign	549892491	RCV000570641\|RCV000604923\|RCV000649478;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN169374\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	228383	228383	5:g.228383C>T	ClinGen:CA3172945	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.706G>A (p.Ala236Thr)	6389	SDHA	Uncertain significance	774160524	RCV000558609\|RCV002367928\|RCV003476315;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	228384	228384	5:g.228384G>A	ClinGen:CA3172946	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.707C>T (p.Ala236Val)	6389	SDHA	Uncertain significance	1060503703	RCV000458180\|RCV002365668\|RCV002469160;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	5	228385	228385	NC_000005.9:g.228385C>T	ClinGen:CA16611938	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.708A>G (p.Ala236=)	6389	SDHA	Likely benign	774277601	RCV002171005;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	228386	228386	228386	-
NM_004168.4(SDHA):c.709C>T (p.Leu237=)	6389	SDHA	Likely benign	1735173554	RCV001399848\|RCV002368256;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	228387	228387	228387	-
NM_004168.4(SDHA):c.709C>G (p.Leu237Val)	6389	SDHA	Uncertain significance	-1	RCV003048559\|RCV003274168;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	228387	228387	NC_000005.9:g.228387C>G	-
NM_004168.4(SDHA):c.712T>G (p.Cys238Gly)	6389	SDHA	Uncertain significance	1579391373	RCV001026073\|RCV001222388;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	228390	228390	5:g.228390T>G	-
NM_004168.4(SDHA):c.713G>T (p.Cys238Phe)	6389	SDHA	Uncertain significance	1168458733	RCV000534290;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	228391	228391	NC_000005.9:g.228391G>T	ClinGen:CA359011016	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.713G>C (p.Cys238Ser)	6389	SDHA	Uncertain significance	1168458733	RCV002030218;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	228391	228391	228391	-
NM_004168.4(SDHA):c.714C>T (p.Cys238=)	6389	SDHA	Likely benign	-1	RCV002917959;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	228392	228392		-
NM_004168.4(SDHA):c.715A>G (p.Ile239Val)	6389	SDHA	Uncertain significance	760106352	RCV000461851\|RCV000561650;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	228393	228393	NC_000005.9:g.228393A>G	ClinGen:CA3172948	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.715A>C (p.Ile239Leu)	6389	SDHA	Uncertain significance	760106352	RCV001325600\|RCV002366202;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	228393	228393	228393	-
NM_004168.4(SDHA):c.715A>T (p.Ile239Leu)	6389	SDHA	Uncertain significance	760106352	RCV001872132;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	228393	228393	228393	-
NM_004168.4(SDHA):c.716T>C (p.Ile239Thr)	6389	SDHA	Uncertain significance	1466069757	RCV001982370\|RCV003434368;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MedGen:C3661900	5	228394	228394	228394	-
NM_004168.4(SDHA):c.716T>G (p.Ile239Arg)	6389	SDHA	Uncertain significance	-1	RCV003475525\|RCV003106870\|RCV003420549;	N	MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|	5	228394	228394	NC_000005.9:g.228394T>G	-
NM_004168.4(SDHA):c.717A>T (p.Ile239=)	6389	SDHA	Likely benign	-1	RCV003082869;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	228395	228395		-
NM_004168.4(SDHA):c.720_722del (p.Glu240del)	6389	SDHA	Uncertain significance	1560990000	RCV000688908;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	228396	228398	NC_000005.9:g.228398_228400del	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.718G>A (p.Glu240Lys)	6389	SDHA	Uncertain significance	1041946	RCV001049666;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	228396	228396	5:g.228396G>A	-
NM_004168.4(SDHA):c.722_726del (p.Asp241fs)	6389	SDHA	Pathogenic	1553998229	RCV000649431\|RCV003456112;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	228398	228402	5:g.228398_228402del	ClinGen:CA658796485	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.720G>A (p.Glu240=)	6389	SDHA	Likely benign	1579391431	RCV001026161\|RCV002552407;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	228398	228398	5:g.228398G>A	-
NM_004168.4(SDHA):c.723C>T (p.Asp241=)	6389	SDHA	Conflicting interpretations of pathogenicity	146653693	RCV000275715\|RCV000334152\|RCV000381733\|RCV000457962\|RCV000562470\|RCV001529253\|RCV001821078;	N	MONDO:MONDO:0017366,MedGen:C1708353, Orphanet:29072\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:00136	5	228401	228401	NC_000005.9:g.228401C>T	ClinGen:CA3172951	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.724G>A (p.Gly242Arg)	6389	SDHA	Uncertain significance	764534044	RCV000227862\|RCV001026197\|RCV003475077;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	228402	228402	NC_000005.9:g.228402G>A	ClinGen:CA3172953	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.726G>A (p.Gly242=)	6389	SDHA	Likely benign	2126559012	RCV002144391\|RCV002382437;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	228404	228404	228404	-
NM_004168.4(SDHA):c.728C>T (p.Ser243Phe)	6389	SDHA	Uncertain significance	756966025	RCV000551321\|RCV002384223;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	228406	228406	NC_000005.9:g.228406C>T	ClinGen:CA3172954	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.728C>G (p.Ser243Cys)	6389	SDHA	Uncertain significance	756966025	RCV001224708;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	228406	228406	5:g.228406C>G	-
NM_004168.4(SDHA):c.729C>T (p.Ser243=)	6389	SDHA	Likely benign	778543446	RCV001492789\|RCV002258287;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	228407	228407	228407	-
NM_004168.4(SDHA):c.730A>G (p.Ile244Val)	6389	SDHA	Uncertain significance	1162393515	RCV000818938\|RCV002381853;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	228408	228408	5:g.228408A>G	-
NM_004168.4(SDHA):c.733C>G (p.His245Asp)	6389	SDHA	Uncertain significance	1060503716	RCV000456392;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	228411	228411	NC_000005.9:g.228411C>G	ClinGen:CA16611831	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.734A>G (p.His245Arg)	6389	SDHA	Uncertain significance	1579391515	RCV001026306\|RCV001862365;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	228412	228412	5:g.228412A>G	-
NM_004168.4(SDHA):c.734A>T (p.His245Leu)	6389	SDHA	Uncertain significance	1579391515	RCV001054031;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	228412	228412	5:g.228412A>T	-
NM_004168.4(SDHA):c.736C>T (p.Arg246Cys)	6389	SDHA	Uncertain significance	1579391530	RCV001026333\|RCV001034942\|RCV002468615;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0031006,MedGen:C5543254,OMIM:619259	5	228414	228414	5:g.228414C>T	-
NM_004168.4(SDHA):c.737G>A (p.Arg246His)	6389	SDHA	Uncertain significance	745309710	RCV001055444\|RCV002379566\|RCV003473657;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	228415	228415	5:g.228415G>A	-
NM_004168.4(SDHA):c.737G>T (p.Arg246Leu)	6389	SDHA	Uncertain significance	745309710	RCV002000580;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	228415	228415	228415	-
NM_004168.4(SDHA):c.738C>T (p.Arg246=)	6389	SDHA	Likely benign	2126559157	RCV002092454\|RCV002386947;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	228416	228416	228416	-
NM_004168.4(SDHA):c.739A>G (p.Ile247Val)	6389	SDHA	Conflicting interpretations of pathogenicity	571292356	RCV000214276\|RCV000230633\|RCV000765826\|RCV000663181;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; M	5	228417	228417	5:g.228417A>G	ClinGen:CA3172957	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.741A>G (p.Ile247Met)	6389	SDHA	Uncertain significance	1735177782	RCV001870866\|RCV003164197;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	228419	228419	228419	-
NM_004168.4(SDHA):c.743G>C (p.Arg248Thr)	6389	SDHA	Uncertain significance	-1	RCV002722133;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	228421	228421	NC_000005.9:g.228421G>C	-
NM_004168.4(SDHA):c.748A>G (p.Lys250Glu)	6389	SDHA	Uncertain significance	1735177925	RCV001338000\|RCV003294325;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	228426	228426	228426	-
NM_004168.4(SDHA):c.749A>G (p.Lys250Arg)	6389	SDHA	Uncertain significance	1060503700	RCV000463173\|RCV002393167\|RCV003324754;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	5	228427	228427	NC_000005.9:g.228427A>G	ClinGen:CA16611833	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.751A>G (p.Asn251Asp)	6389	SDHA	Uncertain significance	-1	RCV003035700;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	228429	228429	NC_000005.9:g.228429A>G	-
NM_004168.4(SDHA):c.752A>C (p.Asn251Thr)	6389	SDHA	Uncertain significance	1318566276	RCV000693374\|RCV003163169;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	228430	228430	5:g.228430A>C	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.753C>G (p.Asn251Lys)	6389	SDHA	Uncertain significance	1126411	RCV000559467\|RCV001026538;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	228431	228431	5:g.228431C>G	ClinGen:CA359011200	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.753C>T (p.Asn251=)	6389	SDHA	Likely benign	1126411	RCV001455157\|RCV002396061;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	228431	228431	228431	-
NM_004168.4(SDHA):c.757_758del (p.Val253fs)	6389	SDHA	Pathogenic/Likely pathogenic	1553998254	RCV000576361\|RCV001381444;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	228434	228435	5:g.228434_228435del	ClinGen:CA658657422	C3279992 614165 Paragangliomas 5;
NM_004168.4(SDHA):c.757G>A (p.Val253Ile)	6389	SDHA	Uncertain significance	1126412	RCV000470372;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	228435	228435	NC_000005.9:g.228435G>A	ClinGen:CA3172960	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.757G>C (p.Val253Leu)	6389	SDHA	Uncertain significance	-1	RCV002644206;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	228435	228435	NC_000005.9:g.228435G>C	-
NM_004168.4(SDHA):c.762_770+17del	6389	SDHA	Pathogenic/Likely pathogenic	1041809852	RCV000456955\|RCV002393168\|RCV002506134\|RCV003316574\|RCV003476122;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; M	5	228439	228464	NC_000005.9:g.228440_228465del	ClinGen:CA16611876	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.763G>A (p.Ala255Thr)	6389	SDHA	Uncertain significance	1735179887	RCV001239987;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	228441	228441	5:g.228441G>A	-
NM_004168.4(SDHA):c.766A>G (p.Thr256Ala)	6389	SDHA	Uncertain significance	1409070000	RCV000694488\|RCV002388256;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	228444	228444	5:g.228444A>G	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.766A>T (p.Thr256Ser)	6389	SDHA	Uncertain significance	1409070000	RCV002047351;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	228444	228444	228444	-
NM_004168.4(SDHA):c.767C>T (p.Thr256Ile)	6389	SDHA	Uncertain significance	2126559328	RCV001976578;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	228445	228445	228445	-
NM_004168.4(SDHA):c.768A>C (p.Thr256=)	6389	SDHA	Likely benign	2126559341	RCV001405323;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	228446	228446	228446	-
NM_004168.4(SDHA):c.768A>T (p.Thr256=)	6389	SDHA	Likely benign	2126559341	RCV001484481;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	228446	228446	228446	-
NM_004168.4(SDHA):c.769_770+77del	6389	SDHA	Likely pathogenic	-1	RCV002966537;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	228446	228524	NC_000005.9:g.228447_228525del	-
NM_004168.4(SDHA):c.770G>A (p.Gly257Glu)	6389	SDHA	Uncertain significance	749566947	RCV001358988;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	228448	228448	228448	-
NM_004168.4(SDHA):c.770G>C (p.Gly257Ala)	6389	SDHA	Conflicting interpretations of pathogenicity	749566947	RCV001885198\|RCV001799815;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|Human Phenotype Ontology:HP:0100723,MONDO:MONDO:0011719,MeSH:D046152,MedGen:C0238198,OMIM:606764, Orphanet:44890	5	228448	228448	228448	-
NM_004168.4(SDHA):c.770+3A>G	6389	SDHA	Uncertain significance	-1	RCV002876035;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	228451	228451	NC_000005.9:g.228451A>G	-
NM_004168.4(SDHA):c.770+7A>C	6389	SDHA	Likely benign	770997653	RCV001455596;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	228455	228455	5:g.228455A>C	-
NM_004168.4(SDHA):c.770+7A>T	6389	SDHA	Likely benign	770997653	RCV002126413;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	228455	228455	228455	-
NM_004168.4(SDHA):c.770+9C>G	6389	SDHA	Likely benign	538621686	RCV001506042;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	228457	228457	228457	-
NM_004168.4(SDHA):c.770+10T>G	6389	SDHA	Likely benign	1579391739	RCV001506721;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	228458	228458	5:g.228458T>G	-
NM_004168.4(SDHA):c.771-11A>G	6389	SDHA	Benign	2288461	RCV000245369\|RCV000281527\|RCV000330761\|RCV000375985\|RCV000492269\|RCV001544159\|RCV001594904\|RCV001544160\|RCV003316406;	N	MedGen:CN169374\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506\|MONDO:MONDO:0017366,MedGen:C1708353, Orphanet:29072\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:14016	5	230980	230980	NC_000005.9:g.230980A>G	ClinGen:CA3172990	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.771-4C>G	6389	SDHA	Likely benign	1360537551	RCV001479132;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	230987	230987	230987	-
NM_004168.4(SDHA):c.771-4C>T	6389	SDHA	Conflicting interpretations of pathogenicity	1360537551	RCV002113214\|RCV002398234;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	230987	230987	230987	-
NM_004168.4(SDHA):c.771-1G>C	6389	SDHA	Likely pathogenic	1735353141	RCV001378546\|RCV003473911;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	230990	230990	230990	-
NM_004168.4(SDHA):c.772G>T (p.Gly258Cys)	6389	SDHA	Uncertain significance	-1	RCV002802206;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	230992	230992	NC_000005.9:g.230992G>T	-
NM_004168.4(SDHA):c.774C>T (p.Gly258=)	6389	SDHA	Likely benign	2126567779	RCV001480757;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	230994	230994	230994	-
NM_004168.4(SDHA):c.774C>A (p.Gly258=)	6389	SDHA	Likely benign	2126567779	RCV002208173;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	230994	230994	230994	-
NM_004168.4(SDHA):c.775del (p.Tyr259fs)	6389	SDHA	Conflicting interpretations of pathogenicity	1553998606	RCV000572546\|RCV000778763\|RCV000810235;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	230995	230995	NC_000005.9:g.230995del	ClinGen:CA658657423
NM_004168.4(SDHA):c.776A>G (p.Tyr259Cys)	6389	SDHA	Uncertain significance	1579397049	RCV000809667\|RCV002406818\|RCV003320757;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	5	230996	230996	5:g.230996A>G	-
NM_004168.4(SDHA):c.777C>T (p.Tyr259=)	6389	SDHA	Conflicting interpretations of pathogenicity	140243793	RCV000234552\|RCV000567901\|RCV001153420\|RCV001153422\|RCV001153421\|RCV003430784;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506\|MO	5	230997	230997	NC_000005.9:g.230997C>T	ClinGen:CA3172993	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.778G>A (p.Gly260Arg)	6389	SDHA	Pathogenic/Likely pathogenic	940845256	RCV000460623\|RCV001026811\|RCV001775823\|RCV003476124;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642	5	230998	230998	NC_000005.9:g.230998G>A	ClinGen:CA16611878	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.778G>C (p.Gly260Arg)	6389	SDHA	Pathogenic/Likely pathogenic	940845256	RCV001377775\|RCV001836652\|RCV002413906;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0031006,MedGen:C5543254,OMIM:619259\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	230998	230998	230998	-
NM_004168.4(SDHA):c.781C>T (p.Arg261Cys)	6389	SDHA	Uncertain significance	143484394	RCV000649447\|RCV002406450;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	231001	231001	NC_000005.9:g.231001C>T	ClinGen:CA3172995	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.782G>A (p.Arg261His)	6389	SDHA	Uncertain significance	769228279	RCV001365806\|RCV002413873;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	231002	231002	231002	-
NM_004168.4(SDHA):c.783C>T (p.Arg261=)	6389	SDHA	Likely benign	1037927856	RCV000930451;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	231003	231003	5:g.231003C>T	-
NM_004168.4(SDHA):c.786del (p.Tyr263fs)	6389	SDHA	Pathogenic/Likely pathogenic	1553998613	RCV000627471\|RCV001855336\|RCV002413782\|RCV003316778;	N	MedGen:C3661900\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165	5	231005	231005	NC_000005.9:g.231006del	ClinGen:CA658796487
NM_004168.4(SDHA):c.785C>T (p.Thr262Ile)	6389	SDHA	Uncertain significance	1579397115	RCV000815298\|RCV001026883\|RCV003472426;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	231005	231005	5:g.231005C>T	-
NM_004168.4(SDHA):c.786C>T (p.Thr262=)	6389	SDHA	Likely benign	1560992315	RCV002155622\|RCV002409534;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	231006	231006	231006	-
NM_004168.4(SDHA):c.788A>G (p.Tyr263Cys)	6389	SDHA	Uncertain significance	2126567907	RCV001930654;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	231008	231008	231008	-
NM_004168.4(SDHA):c.789C>T (p.Tyr263=)	6389	SDHA	Likely benign	1553998616	RCV000649468\|RCV002422382;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	231009	231009	NC_000005.9:g.231009C>T	ClinGen:CA442691470	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.791T>G (p.Phe264Cys)	6389	SDHA	Uncertain significance	2126567940	RCV001368599;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	231011	231011	231011	-
NM_004168.4(SDHA):c.792C>G (p.Phe264Leu)	6389	SDHA	Uncertain significance	1237513803	RCV000535514\|RCV002420505\|RCV001821587;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN169374	5	231012	231012	5:g.231012C>G	ClinGen:CA359011581	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.792C>T (p.Phe264=)	6389	SDHA	Likely benign	1237513803	RCV001479819;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	231012	231012	231012	-
NM_004168.4(SDHA):c.793A>T (p.Ser265Cys)	6389	SDHA	Uncertain significance	2126567967	RCV002027846;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	231013	231013	231013	-
NM_004168.4(SDHA):c.795C>T (p.Ser265=)	6389	SDHA	Likely benign	1579397171	RCV000877990\|RCV002416088;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	231015	231015	5:g.231015C>T	-
NM_004168.4(SDHA):c.796T>C (p.Cys266Arg)	6389	SDHA	Uncertain significance	1579397179	RCV000799284;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	231016	231016	5:g.231016T>C	-
NM_004168.4(SDHA):c.800C>T (p.Thr267Met)	6389	SDHA	Uncertain significance	777167108	RCV000477464\|RCV001027056;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	231020	231020	NC_000005.9:g.231020C>T	ClinGen:CA3172997	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.801G>A (p.Thr267=)	6389	SDHA	Likely benign	543630901	RCV000457309\|RCV001027072\|RCV001696814;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	5	231021	231021	NC_000005.9:g.231021G>A	ClinGen:CA3172998	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.805G>A (p.Ala269Thr)	6389	SDHA	Uncertain significance	1579397217	RCV000798224;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	231025	231025	5:g.231025G>A	-
NM_004168.4(SDHA):c.807C>A (p.Ala269=)	6389	SDHA	Likely benign	-1	RCV002419387\|RCV003120969;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	231027	231027		-
NM_004168.4(SDHA):c.809A>T (p.His270Leu)	6389	SDHA	Uncertain significance	1381228775	RCV001041664\|RCV003160275\|RCV002479266;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154; MO	5	231029	231029	5:g.231029A>T	-
NM_004168.4(SDHA):c.809_814del (p.His270_Ser272delinsArg)	6389	SDHA	Uncertain significance	2126568112	RCV001363743;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	231029	231034	231028	-
NM_004168.4(SDHA):c.810C>T (p.His270=)	6389	SDHA	Likely benign	1199457341	RCV001027185\|RCV001428715;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	231030	231030	5:g.231030C>T	-
NM_004168.4(SDHA):c.812C>G (p.Thr271Ser)	6389	SDHA	Uncertain significance	765611464	RCV000463083\|RCV000765827\|RCV001775822\|RCV002418426;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MOND	5	231032	231032	NC_000005.9:g.231032C>G	ClinGen:CA3172999	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.812C>T (p.Thr271Ile)	6389	SDHA	Uncertain significance	765611464	RCV000816383\|RCV002415913;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	231032	231032	5:g.231032C>T	-
NM_004168.4(SDHA):c.817A>G (p.Thr273Ala)	6389	SDHA	Uncertain significance	1735357615	RCV001230323;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	231037	231037	5:g.231037A>G	-
NM_004168.4(SDHA):c.818C>T (p.Thr273Ile)	6389	SDHA	Conflicting interpretations of pathogenicity	587781720	RCV000129906\|RCV000409578\|RCV000649428\|RCV001818307;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|	5	231038	231038	5:g.231038C>T	ClinGen:CA165326	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.819T>G (p.Thr273=)	6389	SDHA	Likely benign	-1	RCV002721920;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	231039	231039		-
NM_004168.4(SDHA):c.822C>T (p.Gly274=)	6389	SDHA	Conflicting interpretations of pathogenicity	34771391	RCV000210510\|RCV000287211\|RCV000317795\|RCV000372488\|RCV000426962\|RCV000570502\|RCV003316165;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO	5	231042	231042	NC_000005.9:g.231042C>T	ClinGen:CA358575	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.822C>A (p.Gly274=)	6389	SDHA	Likely benign	34771391	RCV000551101;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	231042	231042	5:g.231042C>A	ClinGen:CA442691490	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.823G>A (p.Asp275Asn)	6389	SDHA	Uncertain significance	1553998629	RCV000527085\|RCV002413611;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	231043	231043	5:g.231043G>A	ClinGen:CA359011699	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.825C>T (p.Asp275=)	6389	SDHA	Benign/Likely benign	1237373391	RCV000539832\|RCV002255457;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	231045	231045	NC_000005.9:g.231045C>T	ClinGen:CA442691492	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.826G>A (p.Gly276Ser)	6389	SDHA	Uncertain significance	751008647	RCV000472703\|RCV000663336\|RCV002429556;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	231046	231046	NC_000005.9:g.231046G>A	ClinGen:CA3173001	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.828C>T (p.Gly276=)	6389	SDHA	Uncertain significance	754910183	RCV000547755;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	231048	231048	NC_000005.9:g.231048C>T	ClinGen:CA442691494	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.828C>A (p.Gly276=)	6389	SDHA	Likely benign	754910183	RCV001468959;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	231048	231048	231048	-
NM_004168.4(SDHA):c.829A>G (p.Thr277Ala)	6389	SDHA	Uncertain significance	1553998638	RCV000566367\|RCV001859970;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	231049	231049	5:g.231049A>G	ClinGen:CA359011741	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.830C>T (p.Thr277Met)	6389	SDHA	Conflicting interpretations of pathogenicity	367721665	RCV000208222\|RCV000228322\|RCV000342145\|RCV000283732\|RCV000396726\|RCV000411374\|RCV000570331\|RCV002510820\|RCV003474989;	N	Human Phenotype Ontology:HP:0003756,MONDO:MONDO:0020120,MedGen:C1533847, Orphanet:98472\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0017366,MedGen:C1708353,Orpha	5	231050	231050	5:g.231050C>T	ClinGen:CA069792	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.830C>A (p.Thr277Lys)	6389	SDHA	Uncertain significance	367721665	RCV000649456\|RCV002424510\|RCV003472048;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	231050	231050	NC_000005.9:g.231050C>A	ClinGen:CA3173003	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.831G>A (p.Thr277=)	6389	SDHA	Likely benign	1470632146	RCV000528017\|RCV002431684;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	231051	231051	NC_000005.9:g.231051G>A	ClinGen:CA442691497	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.832G>A (p.Ala278Thr)	6389	SDHA	Uncertain significance	1178613645	RCV001236446\|RCV002436923;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	231052	231052	5:g.231052G>A	-
NM_004168.4(SDHA):c.834C>T (p.Ala278=)	6389	SDHA	Likely benign	1553998649	RCV000540465\|RCV000573575;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	231054	231054	5:g.231054C>T	ClinGen:CA442691500	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.835A>G (p.Met279Val)	6389	SDHA	Uncertain significance	755913710	RCV000468486\|RCV002436467;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	231055	231055	NC_000005.9:g.231055A>G	ClinGen:CA3173004	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.835A>T (p.Met279Leu)	6389	SDHA	Uncertain significance	755913710	RCV001201690\|RCV003293991;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	231055	231055	5:g.231055A>T	-
NM_004168.4(SDHA):c.836T>C (p.Met279Thr)	6389	SDHA	Uncertain significance	777595710	RCV001039066\|RCV002434447;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	231056	231056	5:g.231056T>C	-
NM_004168.4(SDHA):c.837G>T (p.Met279Ile)	6389	SDHA	Uncertain significance	746145822	RCV000703041\|RCV002440522\|RCV003238191;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	5	231057	231057	NC_000005.9:g.231057G>T	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.837G>C (p.Met279Ile)	6389	SDHA	Uncertain significance	-1	RCV002614584;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	231057	231057	NC_000005.9:g.231057G>C	-
NM_004168.4(SDHA):c.839T>A (p.Ile280Asn)	6389	SDHA	Uncertain significance	2126568391	RCV001974588\|RCV002441074;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	231059	231059	231059	-
NM_004168.4(SDHA):c.840C>G (p.Ile280Met)	6389	SDHA	Uncertain significance	2126568400	RCV001899746;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	231060	231060	231060	-
NM_004168.4(SDHA):c.841A>G (p.Thr281Ala)	6389	SDHA	Uncertain significance	772325115	RCV000662906\|RCV000818760\|RCV002442385\|RCV002493076\|RCV003420161\|RCV003472060;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|	5	231061	231061	NC_000005.9:g.231061A>G	-	C3279992 614165 Paragangliomas 5;
NM_004168.4(SDHA):c.842C>G (p.Thr281Ser)	6389	SDHA	Uncertain significance	-1	RCV003080221;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	231062	231062	NC_000005.9:g.231062C>G	-
NM_004168.4(SDHA):c.844A>G (p.Arg282Gly)	6389	SDHA	Uncertain significance	1553998658	RCV000553235;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	231064	231064	5:g.231064A>G	ClinGen:CA359011802	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.845G>C (p.Arg282Thr)	6389	SDHA	Uncertain significance	1735361111	RCV001300894\|RCV003373108;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	231065	231065	231065	-
NM_004168.4(SDHA):c.846G>A (p.Arg282=)	6389	SDHA	Likely benign	1579397464	RCV000981454\|RCV002445136;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	231066	231066	5:g.231066G>A	-
NM_004168.4(SDHA):c.848C>T (p.Ala283Val)	6389	SDHA	Uncertain significance	-1	RCV002815762;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	231068	231068	NC_000005.9:g.231068C>T	-
NM_004168.4(SDHA):c.852C>G (p.Gly284=)	6389	SDHA	Likely benign	552108762	RCV000529223\|RCV003343916;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	231072	231072	5:g.231072C>G	ClinGen:CA3173008	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.852C>A (p.Gly284=)	6389	SDHA	Likely benign	552108762	RCV000872455\|RCV002444941;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	231072	231072	5:g.231072C>A	-
NM_004168.4(SDHA):c.853C>T (p.Leu285Phe)	6389	SDHA	Uncertain significance	747045191	RCV000649446\|RCV001017973;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	231073	231073	5:g.231073C>T	ClinGen:CA3173009	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.856C>T (p.Pro286Ser)	6389	SDHA	Uncertain significance	1579397496	RCV001018011\|RCV000801027;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	231076	231076	5:g.231076C>T	-
NM_004168.4(SDHA):c.858T>A (p.Pro286=)	6389	SDHA	Likely benign	1553998661	RCV000574929\|RCV000871585;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	231078	231078	5:g.231078T>A	ClinGen:CA442691515	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.859T>A (p.Cys287Ser)	6389	SDHA	Uncertain significance	2126568567	RCV001908455;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	231079	231079	231079	-
NM_004168.4(SDHA):c.861C>G (p.Cys287Trp)	6389	SDHA	Uncertain significance	140797184	RCV000705741\|RCV002369962;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	231081	231081	5:g.231081C>G	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.861C>T (p.Cys287=)	6389	SDHA	Likely benign	-1	RCV003052924\|RCV003340602;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	231081	231081		-
NM_004168.4(SDHA):c.865G>T (p.Asp289Tyr)	6389	SDHA	Uncertain significance	2126568625	RCV001902838;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	231085	231085	231085	-
NM_004168.4(SDHA):c.865G>A (p.Asp289Asn)	6389	SDHA	Uncertain significance	-1	RCV002685566;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	231085	231085	NC_000005.9:g.231085G>A	-
NM_004168.4(SDHA):c.867C>G (p.Asp289Glu)	6389	SDHA	Uncertain significance	-1	RCV002449681\|RCV003100000;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	231087	231087	231087	-
NM_004168.4(SDHA):c.867C>T (p.Asp289=)	6389	SDHA	Likely benign	-1	RCV002686012;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	231087	231087		-
NM_004168.4(SDHA):c.868C>T (p.Leu290=)	6389	SDHA	Likely benign	2126568639	RCV001430654;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	231088	231088	231088	-
NM_004168.4(SDHA):c.869T>C (p.Leu290Pro)	6389	SDHA	Uncertain significance	1333787672	RCV001051573\|RCV002374907\|RCV003473645;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	231089	231089	5:g.231089T>C	-
NM_004168.4(SDHA):c.871G>A (p.Glu291Lys)	6389	SDHA	Uncertain significance	1579397516	RCV000810928\|RCV002370178;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	231091	231091	5:g.231091G>A	-
NM_004168.4(SDHA):c.872A>T (p.Glu291Val)	6389	SDHA	Uncertain significance	1336029027	RCV000795093\|RCV002370081;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	231092	231092	5:g.231092A>T	-
NM_004168.4(SDHA):c.872A>C (p.Glu291Ala)	6389	SDHA	Uncertain significance	-1	RCV002373489\|RCV003100010;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	231092	231092	231092	-
NM_004168.4(SDHA):c.872A>G (p.Glu291Gly)	6389	SDHA	Uncertain significance	-1	RCV002658108;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	231092	231092	NC_000005.9:g.231092A>G	-
NM_004168.4(SDHA):c.873G>A (p.Glu291=)	6389	SDHA	Likely benign	570393010	RCV000463231\|RCV001018260;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	231093	231093	NC_000005.9:g.231093G>A	ClinGen:CA3173011	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.875T>G (p.Phe292Cys)	6389	SDHA	Uncertain significance	2126568674	RCV002029830;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	231095	231095	231095	-
NM_004168.4(SDHA):c.880C>T (p.Gln294Ter)	6389	SDHA	Pathogenic	1560992565	RCV000706931\|RCV002442539\|RCV003316801;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	231100	231100	NC_000005.9:g.231100C>T	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.880C>A (p.Gln294Lys)	6389	SDHA	Uncertain significance	-1	RCV003006201;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	231100	231100	NC_000005.9:g.231100C>A	-
NM_004168.4(SDHA):c.882G>T (p.Gln294His)	6389	SDHA	Uncertain significance	371512265	RCV001935495;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	231102	231102	231102	-
NM_004168.4(SDHA):c.882G>A (p.Gln294=)	6389	SDHA	Likely benign	-1	RCV002373772\|RCV003100037;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	231102	231102		-
NM_004168.4(SDHA):c.884T>A (p.Phe295Tyr)	6389	SDHA	Uncertain significance	1735363396	RCV001344327;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	231104	231104	231104	-
NM_004168.4(SDHA):c.886C>T (p.His296Tyr)	6389	SDHA	Uncertain significance	1579397566	RCV001018428\|RCV001049537;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	231106	231106	5:g.231106C>T	-
NM_004168.4(SDHA):c.888C>T (p.His296=)	6389	SDHA	Likely benign	1553998666	RCV001475500;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	231108	231108	NC_000005.9:g.231108C>T	ClinGen:CA442691530	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.889C>T (p.Pro297Ser)	6389	SDHA	Uncertain significance	1224049075	RCV001054039;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	231109	231109	5:g.231109C>T	-
NM_004168.4(SDHA):c.890_891delinsTC (p.Pro297Leu)	6389	SDHA	Uncertain significance	1579397592	RCV001018484\|RCV001240518;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	231110	231111	NC_000005.9:g.231110_231111delinsTC	-
NM_004168.4(SDHA):c.891T>C (p.Pro297=)	6389	SDHA	Benign	1126417	RCV000118321\|RCV000162482\|RCV000308030\|RCV000347829\|RCV000400279\|RCV001509670\|RCV001544164\|RCV001544165\|RCV001711387\|RCV003315685;	N	MedGen:CN169374\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0017366,MedGen:C1708353, Orphanet:29072\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:50	5	231111	231111	5:g.231111T>C	ClinGen:CA155160	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.891T>G (p.Pro297=)	6389	SDHA	Likely benign	1126417	RCV001421869\|RCV003298712;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	231111	231111	231111	-
NM_004168.4(SDHA):c.894A>G (p.Thr298=)	6389	SDHA	Likely benign	774584410	RCV000531297\|RCV002377146;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	231114	231114	NC_000005.9:g.231114A>G	ClinGen:CA3173013	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.895+1del	6389	SDHA	Likely pathogenic	2126568833	RCV001995700\|RCV003453916;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	231115	231115	231114	-
NM_004168.4(SDHA):c.895+4G>A	6389	SDHA	Uncertain significance	1735364791	RCV001343753;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	231119	231119	231119	-
NM_004168.4(SDHA):c.895+6G>A	6389	SDHA	Likely benign	765946047	RCV001061641;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	231121	231121	5:g.231121G>A	-
NM_004168.4(SDHA):c.895+8A>G	6389	SDHA	Likely benign	892273080	RCV000869860;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	231123	231123	5:g.231123A>G	-
NM_004168.4(SDHA):c.895+9G>A	6389	SDHA	Likely benign	1579397653	RCV001441334;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	231124	231124	5:g.231124G>A	-
NM_004168.4(SDHA):c.895+13G>A	6389	SDHA	Conflicting interpretations of pathogenicity	201461936	RCV000440704\|RCV000662985\|RCV001157730\|RCV001157731\|RCV001157732\|RCV002256236;	N	MedGen:CN169374\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506\|MONDO:MONDO:0017366,MedGen:C1708353, Orphanet:29072\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|	5	231128	231128	5:g.231128G>A	ClinGen:CA3173017	CN169374 not specified;
NM_004168.4(SDHA):c.896-11G>T	6389	SDHA	Uncertain significance	774043076	RCV001157734\|RCV001157733\|RCV001157735\|RCV002256692;	N	MONDO:MONDO:0017366,MedGen:C1708353, Orphanet:29072\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233581	233581	5:g.233581G>T	-
NM_004168.4(SDHA):c.896-10T>G	6389	SDHA	Uncertain significance	2126576716	RCV001877059;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	233582	233582	233582	-
NM_004168.4(SDHA):c.896-5del	6389	SDHA	Benign	751123858	RCV002132498;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	233582	233582	233581	-
NM_004168.4(SDHA):c.896-5T>G	6389	SDHA	Uncertain significance	2126576742	RCV001915553;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	233587	233587	233587	-
NM_004168.4(SDHA):c.896-4G>A	6389	SDHA	Conflicting interpretations of pathogenicity	555881974	RCV000543768\|RCV003316720\|RCV002448768;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233588	233588	NC_000005.9:g.233588G>A	ClinGen:CA3173037	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.896-3C>T	6389	SDHA	Uncertain significance	1735543080	RCV001341902;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233589	233589	233589	-
NM_004168.4(SDHA):c.896-2del	6389	SDHA	Likely pathogenic	-1	RCV003046279;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233590	233590	NC_000005.9:g.233590del	-
NM_004168.4(SDHA):c.897C>T (p.Gly299=)	6389	SDHA	Likely benign	1484385016	RCV000797742\|RCV002370095;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233593	233593	5:g.233593C>T	-
NM_004168.4(SDHA):c.898A>C (p.Ile300Leu)	6389	SDHA	Uncertain significance	1448561231	RCV000812836;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233594	233594	5:g.233594A>C	-
NM_004168.4(SDHA):c.898A>G (p.Ile300Val)	6389	SDHA	Uncertain significance	-1	RCV002376276\|RCV003100074;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233594	233594	233594	-
NM_004168.4(SDHA):c.899T>C (p.Ile300Thr)	6389	SDHA	Uncertain significance	878854637	RCV000232508\|RCV001018599;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233595	233595	5:g.233595T>C	ClinGen:CA10582423	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.900A>G (p.Ile300Met)	6389	SDHA	Uncertain significance	1735543603	RCV001314057;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233596	233596	233596	-
NM_004168.4(SDHA):c.901T>C (p.Tyr301His)	6389	SDHA	Uncertain significance	1060503713	RCV000477068\|RCV002374817;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233597	233597	NC_000005.9:g.233597T>C	ClinGen:CA16611939	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.902A>G (p.Tyr301Cys)	6389	SDHA	Uncertain significance	182055219	RCV001018684\|RCV000765828\|RCV000701878;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MO	5	233598	233598	NC_000005.9:g.233598A>G	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.905G>A (p.Gly302Asp)	6389	SDHA	Uncertain significance	1735544082	RCV001323316\|RCV001586126\|RCV002377407;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233601	233601	233601	-
NM_004168.4(SDHA):c.907G>T (p.Ala303Ser)	6389	SDHA	Uncertain significance	2126576840	RCV001993004\|RCV002370603;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233603	233603	233603	-
NM_004168.4(SDHA):c.914G>T (p.Cys305Phe)	6389	SDHA	Uncertain significance	878854638	RCV000234148;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233610	233610	5:g.233610G>T	ClinGen:CA10582424	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.914G>A (p.Cys305Tyr)	6389	SDHA	Uncertain significance	878854638	RCV000468097\|RCV000575963\|RCV000662791\|RCV003313078;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|	5	233610	233610	NC_000005.9:g.233610G>A	ClinGen:CA16611838	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.916C>G (p.Leu306Val)	6389	SDHA	Uncertain significance	1735544893	RCV001227668;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233612	233612	5:g.233612C>G	-
NM_004168.4(SDHA):c.917T>C (p.Leu306Pro)	6389	SDHA	Uncertain significance	1477142607	RCV001981723;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233613	233613	233613	-
NM_004168.4(SDHA):c.918C>G (p.Leu306=)	6389	SDHA	Benign/Likely benign	138828792	RCV000239363\|RCV000568221\|RCV002479953;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN169374	5	233614	233614	NC_000005.9:g.233614C>G	ClinGen:CA3173039	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.918C>T (p.Leu306=)	6389	SDHA	Likely benign	138828792	RCV000877742\|RCV001018968;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233614	233614	5:g.233614C>T	-
NM_004168.4(SDHA):c.918C>A (p.Leu306=)	6389	SDHA	Likely benign	138828792	RCV001452109;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	233614	233614	5:g.233614C>A	-
NM_004168.4(SDHA):c.919A>G (p.Ile307Val)	6389	SDHA	Uncertain significance	200632016	RCV000229059\|RCV001018991\|RCV002503908;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154; MO	5	233615	233615	5:g.233615A>G	ClinGen:CA10582425	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.921T>C (p.Ile307=)	6389	SDHA	Likely benign	-1	RCV002867652;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233617	233617		-
NM_004168.4(SDHA):c.923C>T (p.Thr308Met)	6389	SDHA	Conflicting interpretations of pathogenicity	1457666982	RCV000560478\|RCV000563497\|RCV001799682\|RCV003237920;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|Human Phenotype Ontology:HP:0100723,MONDO:MONDO:0011719,MeSH:D0	5	233619	233619	5:g.233619C>T	ClinGen:CA359012572	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.923C>A (p.Thr308Lys)	6389	SDHA	Uncertain significance	-1	RCV003069140;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233619	233619	NC_000005.9:g.233619C>A	-
NM_004168.4(SDHA):c.924G>A (p.Thr308=)	6389	SDHA	Conflicting interpretations of pathogenicity	1355760590	RCV000531991\|RCV002377147;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233620	233620	NC_000005.9:g.233620G>A	ClinGen:CA442691660	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.926A>G (p.Glu309Gly)	6389	SDHA	Uncertain significance	1735547863	RCV001227669\|RCV003473791;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	233622	233622	5:g.233622A>G	-
NM_004168.4(SDHA):c.928G>A (p.Gly310Arg)	6389	SDHA	Uncertain significance	-1	RCV002663467;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233624	233624	NC_000005.9:g.233624G>A	-
NM_004168.4(SDHA):c.930A>C (p.Gly310=)	6389	SDHA	Likely benign	1579402124	RCV001504224;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233626	233626	5:g.233626A>C	-
NM_004168.4(SDHA):c.934_936del (p.Arg312del)	6389	SDHA	Uncertain significance	1735548711	RCV001999182;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	233628	233630	233627	-
NM_004168.4(SDHA):c.933T>C (p.Cys311=)	6389	SDHA	Likely benign	764026731	RCV001019190\|RCV002549500;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233629	233629	5:g.233629T>C	-
NM_004168.4(SDHA):c.934C>T (p.Arg312Cys)	6389	SDHA	Uncertain significance	1735549033	RCV001768271\|RCV001885098\|RCV002370309;	N	MedGen:C3661900\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233630	233630	233630	-
NM_004168.4(SDHA):c.935G>A (p.Arg312His)	6389	SDHA	Uncertain significance	876660932	RCV000692412\|RCV001019215\|RCV003472207;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	233631	233631	5:g.233631G>A	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.935G>T (p.Arg312Leu)	6389	SDHA	Uncertain significance	876660932	RCV001295581\|RCV003166644;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233631	233631	233631	-
NM_004168.4(SDHA):c.936T>G (p.Arg312=)	6389	SDHA	Likely benign	2126577072	RCV002207096;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233632	233632	233632	-
NM_004168.4(SDHA):c.939A>C (p.Gly313=)	6389	SDHA	Likely benign	1579402154	RCV001405606;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233635	233635	5:g.233635A>C	-
NM_004168.4(SDHA):c.940G>A (p.Glu314Lys)	6389	SDHA	Conflicting interpretations of pathogenicity	1337704280	RCV000649440\|RCV002369738;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233636	233636	NC_000005.9:g.233636G>A	ClinGen:CA359012620	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.941A>G (p.Glu314Gly)	6389	SDHA	Uncertain significance	1735550179	RCV001299900\|RCV003473851;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	233637	233637	233637	-
NM_004168.4(SDHA):c.941A>C (p.Glu314Ala)	6389	SDHA	Uncertain significance	1735550179	RCV001959898\|RCV002370556;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233637	233637	233637	-
NM_004168.4(SDHA):c.942G>A (p.Glu314=)	6389	SDHA	Likely benign	1553998977	RCV000544759\|RCV002377148;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233638	233638	NC_000005.9:g.233638G>A	ClinGen:CA442691673	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.942_945delinsTCC (p.Glu314fs)	6389	SDHA	Pathogenic	1579402188	RCV000813707;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233638	233641	5:g.233639_233641del	-
NM_004168.4(SDHA):c.944G>A (p.Gly315Glu)	6389	SDHA	Uncertain significance	1579402194	RCV000816441;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233640	233640	5:g.233640G>A	-
NM_004168.4(SDHA):c.950T>C (p.Ile317Thr)	6389	SDHA	Uncertain significance	903136919	RCV002005616;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233646	233646	233646	-
NM_004168.4(SDHA):c.952C>T (p.Leu318Phe)	6389	SDHA	Uncertain significance	1735551482	RCV001212408;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233648	233648	5:g.233648C>T	-
NM_004168.4(SDHA):c.954C>T (p.Leu318=)	6389	SDHA	Likely benign	1412623947	RCV000566045\|RCV000869875\|RCV002497217;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0031006,MedGen:C5543254,OMIM:619259; MONDO:MONDO:010	5	233650	233650	5:g.233650C>T	ClinGen:CA442691684	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.955A>C (p.Ile319Leu)	6389	SDHA	Conflicting interpretations of pathogenicity	377509915	RCV000462816\|RCV000565889\|RCV000765829\|RCV001821296\|RCV002272249\|RCV003476127;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506; MO	5	233651	233651	NC_000005.9:g.233651A>C	ClinGen:CA3173042	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.955A>G (p.Ile319Val)	6389	SDHA	Uncertain significance	377509915	RCV000662946\|RCV000557149\|RCV001019482;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233651	233651	NC_000005.9:g.233651A>G	ClinGen:CA359012672	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.957T>C (p.Ile319=)	6389	SDHA	Likely benign	757167466	RCV000536309\|RCV001019510;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233653	233653	5:g.233653T>C	ClinGen:CA3173043	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.959A>G (p.Asn320Ser)	6389	SDHA	Uncertain significance	765092091	RCV001019521\|RCV001247226;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233655	233655	5:g.233655A>G	-
NM_004168.4(SDHA):c.960C>T (p.Asn320=)	6389	SDHA	Likely benign	1289327970	RCV001434569\|RCV002372589;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233656	233656	5:g.233656C>T	-
NM_004168.4(SDHA):c.962G>T (p.Ser321Ile)	6389	SDHA	Uncertain significance	751896104	RCV001052866\|RCV002374916;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233658	233658	5:g.233658G>T	-
NM_004168.4(SDHA):c.963T>C (p.Ser321=)	6389	SDHA	Likely benign	755235011	RCV002089432\|RCV003434384;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MedGen:C3661900	5	233659	233659	233659	-
NM_004168.4(SDHA):c.965A>C (p.Gln322Pro)	6389	SDHA	Uncertain significance	1553998989	RCV000649453;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233661	233661	NC_000005.9:g.233661A>C	ClinGen:CA359012705	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.967G>A (p.Gly323Ser)	6389	SDHA	Uncertain significance	1553998991	RCV000649460;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233663	233663	NC_000005.9:g.233663G>A	ClinGen:CA359012713	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.969C>T (p.Gly323=)	6389	SDHA	Conflicting interpretations of pathogenicity	142849100	RCV000129664\|RCV000203785\|RCV000246464\|RCV000314076\|RCV000399972\|RCV000362684\|RCV001357190\|RCV003315880;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MedGen:CN169374\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011	5	233665	233665	5:g.233665C>T	ClinGen:CA345710	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.969C>A (p.Gly323=)	6389	SDHA	Likely benign	142849100	RCV000548814\|RCV002377149;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233665	233665	5:g.233665C>A	ClinGen:CA3173047	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.969C>G (p.Gly323=)	6389	SDHA	Likely benign	-1	RCV002376607\|RCV003094856;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	233665	233665		-
NM_004168.4(SDHA):c.970G>A (p.Glu324Lys)	6389	SDHA	Uncertain significance	147014102	RCV000649457\|RCV000662695\|RCV002369740\|RCV002493038\|RCV003472049;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|	5	233666	233666	5:g.233666G>A	ClinGen:CA3173048	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.973A>T (p.Arg325Trp)	6389	SDHA	Uncertain significance	1735554095	RCV001991877;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233669	233669	233669	-
NM_004168.4(SDHA):c.974G>T (p.Arg325Met)	6389	SDHA	Uncertain significance	1735554223	RCV002006610\|RCV002386896;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233670	233670	233670	-
NM_004168.4(SDHA):c.975G>A (p.Arg325=)	6389	SDHA	Likely benign	1418778005	RCV001482943\|RCV002384787;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233671	233671	233671	-
NM_004168.4(SDHA):c.977T>A (p.Phe326Tyr)	6389	SDHA	Uncertain significance	1735554652	RCV001223393;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233673	233673	5:g.233673T>A	-
NM_004168.4(SDHA):c.979A>G (p.Met327Val)	6389	SDHA	Uncertain significance	1285443776	RCV002031597\|RCV002372823;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233675	233675	233675	-
NM_004168.4(SDHA):c.980T>C (p.Met327Thr)	6389	SDHA	Uncertain significance	2126577482	RCV001884283;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233676	233676	233676	-
NM_004168.4(SDHA):c.982G>C (p.Glu328Gln)	6389	SDHA	Uncertain significance	778297896	RCV001956772;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	233678	233678	233678	-
NM_004168.4(SDHA):c.984G>A (p.Glu328=)	6389	SDHA	Likely benign	1735555420	RCV002382287\|RCV002175371;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	233680	233680	233680	-
NM_004168.4(SDHA):c.985C>T (p.Arg329Ter)	6389	SDHA	Pathogenic	771328239	RCV000462116\|RCV001019810;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233681	233681	NC_000005.9:g.233681C>T	ClinGen:CA16611943	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.985C>G (p.Arg329Gly)	6389	SDHA	Uncertain significance	771328239	RCV000556956\|RCV002384224;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233681	233681	5:g.233681C>G	ClinGen:CA3173054	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.986G>A (p.Arg329Gln)	6389	SDHA	Uncertain significance	138265892	RCV000690290\|RCV001019831\|RCV001771947;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	5	233682	233682	NC_000005.9:g.233682G>A	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.988T>A (p.Tyr330Asn)	6389	SDHA	Uncertain significance	-1	RCV002899145;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233684	233684	NC_000005.9:g.233684T>A	-
NM_004168.4(SDHA):c.990C>T (p.Tyr330=)	6389	SDHA	Likely benign	370547766	RCV000537496\|RCV002384225;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233686	233686	NC_000005.9:g.233686C>T	ClinGen:CA3173057	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.991G>A (p.Ala331Thr)	6389	SDHA	Conflicting interpretations of pathogenicity	200526913	RCV000239369\|RCV000567963\|RCV000765830\|RCV002291613;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154; MO	5	233687	233687	NC_000005.9:g.233687G>A	ClinGen:CA3173058	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.991G>T (p.Ala331Ser)	6389	SDHA	Uncertain significance	200526913	RCV001936106;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	233687	233687	233687	-
NM_004168.4(SDHA):c.991_992delinsAA (p.Ala331Asn)	6389	SDHA	Uncertain significance	-1	RCV002843230;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233687	233688	NC_000005.9:g.233687_233688delinsAA	-
NM_004168.4(SDHA):c.992C>G (p.Ala331Gly)	6389	SDHA	Uncertain significance	1206201147	RCV000799683;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233688	233688	5:g.233688C>G	-
NM_004168.4(SDHA):c.992C>T (p.Ala331Val)	6389	SDHA	Uncertain significance	1206201147	RCV001322315\|RCV002546094\|RCV003355389;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233688	233688	233688	-
NM_004168.4(SDHA):c.993C>T (p.Ala331=)	6389	SDHA	Likely benign	1424925197	RCV001500175\|RCV002382153;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233689	233689	5:g.233689C>T	-
NM_004168.4(SDHA):c.994C>G (p.Pro332Ala)	6389	SDHA	Uncertain significance	373509391	RCV000194437\|RCV000229794\|RCV000563954\|RCV001558313\|RCV003474947;	N	MedGen:CN169374\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900\|MONDO:MONDO:0013339,MedGen:C315	5	233690	233690	5:g.233690C>G	ClinGen:CA208608	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.995_996del (p.Pro332fs)	6389	SDHA	Pathogenic	1560994766	RCV000697696\|RCV002386222\|RCV003148832\|RCV003313134;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|	5	233691	233692	5:g.233691_233692del	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.996_998delinsCAC (p.Val333Thr)	6389	SDHA	Uncertain significance	1057517540	RCV000410220\|RCV000649427\|RCV002379266;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233692	233694	NC_000005.9:g.233692_233694delinsCAC	ClinGen:CA16042100	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.996_997inv (p.Val333Ile)	6389	SDHA	Uncertain significance	-1	RCV000473544\|RCV002383837;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233692	233693	NC_000005.9:g.233692_233693inv	ClinGen:CA16611881	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.997G>C (p.Val333Leu)	6389	SDHA	Uncertain significance	1062468	RCV000469550\|RCV002383836\|RCV002489089;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072;	5	233693	233693	NC_000005.9:g.233693G>C	ClinGen:CA16611946	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.997G>A (p.Val333Ile)	6389	SDHA	Uncertain significance	1062468	RCV001301605\|RCV002384359;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233693	233693	233693	-
NM_004168.4(SDHA):c.999C>G (p.Val333=)	6389	SDHA	Likely benign	149556555	RCV000525741\|RCV001019964;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233695	233695	NC_000005.9:g.233695C>G	ClinGen:CA3173061	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.999C>T (p.Val333=)	6389	SDHA	Likely benign	149556555	RCV000867551\|RCV001019965;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233695	233695	5:g.233695C>T	-
NM_004168.4(SDHA):c.999C>A (p.Val333=)	6389	SDHA	Likely benign	-1	RCV002383062\|RCV003103626;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	233695	233695		-
NM_004168.4(SDHA):c.1000G>A (p.Ala334Thr)	6389	SDHA	Uncertain significance	1401459296	RCV000533503\|RCV002350351;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233696	233696	5:g.233696G>A	ClinGen:CA359012819	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1000G>T (p.Ala334Ser)	6389	SDHA	Uncertain significance	-1	RCV002303643\|RCV002363753;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233696	233696	233696	-
NM_004168.4(SDHA):c.1001C>T (p.Ala334Val)	6389	SDHA	Uncertain significance	765180271	RCV000546125\|RCV001009632\|RCV002483478\|RCV002272285;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072;	5	233697	233697	NC_000005.9:g.233697C>T	ClinGen:CA3173062	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1002G>A (p.Ala334=)	6389	SDHA	Conflicting interpretations of pathogenicity	144252500	RCV000239366\|RCV000570639\|RCV001152241\|RCV001152242\|RCV001152243\|RCV001705321\|RCV001820792\|RCV003316318;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506\|MO	5	233698	233698	NC_000005.9:g.233698G>A	ClinGen:CA3173063	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1004A>C (p.Lys335Thr)	6389	SDHA	Uncertain significance	1560994846	RCV000696711;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233700	233700	NC_000005.9:g.233700A>C	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1005G>A (p.Lys335=)	6389	SDHA	Likely benign	1735559685	RCV001237573;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233701	233701	5:g.233701G>A	-
NM_004168.4(SDHA):c.1005G>C (p.Lys335Asn)	6389	SDHA	Uncertain significance	1735559685	RCV002010167;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233701	233701	233701	-
NM_004168.4(SDHA):c.1006G>T (p.Asp336Tyr)	6389	SDHA	Uncertain significance	1553999038	RCV000662766\|RCV000707079\|RCV001016968;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233702	233702	5:g.233702G>T	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1007A>C (p.Asp336Ala)	6389	SDHA	Uncertain significance	1579402533	RCV000799695;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233703	233703	5:g.233703A>C	-
NM_004168.4(SDHA):c.1009C>T (p.Leu337=)	6389	SDHA	Likely benign	-1	RCV002610974;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233705	233705		-
NM_004168.4(SDHA):c.1012del (p.Ala338fs)	6389	SDHA	Pathogenic	1295239305	RCV001383279\|RCV002357289\|RCV002508961;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072;	5	233707	233707	233706	-
NM_004168.4(SDHA):c.1012G>A (p.Ala338Thr)	6389	SDHA	Uncertain significance	2126577878	RCV001963665\|RCV002224126;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MedGen:C3661900	5	233708	233708	233708	-
NM_004168.4(SDHA):c.1013C>T (p.Ala338Val)	6389	SDHA	Uncertain significance	1560994866	RCV000706884\|RCV003165926;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233709	233709	5:g.233709C>T	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1014G>A (p.Ala338=)	6389	SDHA	Conflicting interpretations of pathogenicity	201341132	RCV000456689\|RCV000563364\|RCV001152245\|RCV001152244\|RCV001152246\|RCV001310840;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|M	5	233710	233710	NC_000005.9:g.233710G>A	ClinGen:CA3173065	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1014G>T (p.Ala338=)	6389	SDHA	Likely benign	201341132	RCV001499559\|RCV003161005;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233710	233710	233710	-
NM_004168.4(SDHA):c.1016C>T (p.Ser339Phe)	6389	SDHA	Uncertain significance	1553999043	RCV000649398;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233712	233712	5:g.233712C>T	ClinGen:CA359012877	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1016C>G (p.Ser339Cys)	6389	SDHA	Uncertain significance	1553999043	RCV001326356\|RCV002350606;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233712	233712	233712	-
NM_004168.4(SDHA):c.1017T>C (p.Ser339=)	6389	SDHA	Likely benign	752738784	RCV000568481\|RCV001401268;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233713	233713	5:g.233713T>C	ClinGen:CA442691714	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1019G>T (p.Arg340Ile)	6389	SDHA	Uncertain significance	1579402602	RCV000807121;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233715	233715	5:g.233715G>T	-
NM_004168.4(SDHA):c.1020A>G (p.Arg340=)	6389	SDHA	Likely benign	2126577996	RCV002119564;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	233716	233716	233716	-
NM_004168.4(SDHA):c.1022A>C (p.Asp341Ala)	6389	SDHA	Uncertain significance	1579402616	RCV000811773;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233718	233718	5:g.233718A>C	-
NM_004168.4(SDHA):c.1022A>G (p.Asp341Gly)	6389	SDHA	Uncertain significance	-1	RCV003005569;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233718	233718	NC_000005.9:g.233718A>G	-
NM_004168.4(SDHA):c.1024GTG[1] (p.Val343del)	6389	SDHA	Uncertain significance	2126578027	RCV001864744;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	233720	233722	233719	-
NM_004168.4(SDHA):c.1024G>C (p.Val342Leu)	6389	SDHA	Uncertain significance	1735562520	RCV001864880;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	233720	233720	233720	-
NM_004168.4(SDHA):c.1026G>T (p.Val342=)	6389	SDHA	Likely benign	1060505004	RCV000475138\|RCV002383906;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233722	233722	NC_000005.9:g.233722G>T	ClinGen:CA16611839	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1026G>A (p.Val342=)	6389	SDHA	Likely benign	1060505004	RCV000553862\|RCV002384219;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233722	233722	5:g.233722G>A	ClinGen:CA442691718	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1027G>C (p.Val343Leu)	6389	SDHA	Uncertain significance	2126578052	RCV001923192;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233723	233723	233723	-
NM_004168.4(SDHA):c.1028T>A (p.Val343Glu)	6389	SDHA	Uncertain significance	1218116319	RCV001068605\|RCV002379612\|RCV003473694;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	233724	233724	5:g.233724T>A	-
NM_004168.4(SDHA):c.1028T>C (p.Val343Ala)	6389	SDHA	Uncertain significance	-1	RCV002842203;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233724	233724	NC_000005.9:g.233724T>C	-
NM_004168.4(SDHA):c.1030T>G (p.Ser344Ala)	6389	SDHA	Uncertain significance	1735563330	RCV001208094;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233726	233726	5:g.233726T>G	-
NM_004168.4(SDHA):c.1032_1033del (p.Arg345fs)	6389	SDHA	Pathogenic	2126578081	RCV001381070;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233726	233727	233725	-
NM_004168.4(SDHA):c.1031C>A (p.Ser344Tyr)	6389	SDHA	Uncertain significance	1735563548	RCV001056738\|RCV002379570;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233727	233727	5:g.233727C>A	-
NM_004168.4(SDHA):c.1031C>T (p.Ser344Phe)	6389	SDHA	Uncertain significance	1735563548	RCV001307448;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233727	233727	233727	-
NM_004168.4(SDHA):c.1033C>T (p.Arg345Trp)	6389	SDHA	Uncertain significance	760598746	RCV000575068\|RCV000998345\|RCV001235731\|RCV003471905;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642	5	233729	233729	5:g.233729C>T	ClinGen:CA3173067	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1034G>A (p.Arg345Gln)	6389	SDHA	Uncertain significance	1483236652	RCV000530018\|RCV001017082;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233730	233730	NC_000005.9:g.233730G>A	ClinGen:CA359012928	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1035del (p.Ser346fs)	6389	SDHA	Pathogenic	2126578126	RCV001935112;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	233730	233730	233729	-
NM_004168.4(SDHA):c.1037_1038inv (p.Ser346Trp)	6389	SDHA	Uncertain significance	-1	RCV000694354;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233733	233734	NC_000005.9:g.233733_233734inv	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1037_1038delinsTG (p.Ser346Leu)	6389	SDHA	Uncertain significance	1735564312	RCV001060966\|RCV002393299;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233733	233734	NC_000005.9:g.233733_233734delinsTG	-
NM_004168.4(SDHA):c.1037C>G (p.Ser346Cys)	6389	SDHA	Uncertain significance	1041948	RCV001368729\|RCV003169884;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233733	233733	233733	-
NM_004168.4(SDHA):c.1038C>G (p.Ser346=)	6389	SDHA	Benign	1041949	RCV000118311\|RCV000162943\|RCV000274141\|RCV000319420\|RCV000368680\|RCV001509671\|RCV001711288\|RCV003315675;	N	MedGen:CN169374\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0017366,MedGen:C1708353, Orphanet:29072\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:50	5	233734	233734	5:g.233734C>G	ClinGen:CA155142	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1038C>T (p.Ser346=)	6389	SDHA	Likely benign	1041949	RCV000576001\|RCV000599963\|RCV000932394;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN169374\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233734	233734	5:g.233734C>T	ClinGen:CA3173068	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1039A>G (p.Met347Val)	6389	SDHA	Uncertain significance	1245387180	RCV001359006\|RCV002395791;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233735	233735	233735	-
NM_004168.4(SDHA):c.1040T>C (p.Met347Thr)	6389	SDHA	Uncertain significance	1553999054	RCV000546880\|RCV002395442;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233736	233736	5:g.233736T>C	ClinGen:CA359012947	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1041G>A (p.Met347Ile)	6389	SDHA	Uncertain significance	1560994934	RCV000701089\|RCV001009777;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233737	233737	5:g.233737G>A	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1042A>T (p.Thr348Ser)	6389	SDHA	Uncertain significance	371484111	RCV000469012\|RCV002393169;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233738	233738	NC_000005.9:g.233738A>T	ClinGen:CA3173069	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1042A>G (p.Thr348Ala)	6389	SDHA	Uncertain significance	371484111	RCV000573837\|RCV000804322;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233738	233738	NC_000005.9:g.233738A>G	ClinGen:CA359012961	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1044T>A (p.Thr348=)	6389	SDHA	Likely benign	1553999055	RCV000564316\|RCV001419846;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233740	233740	NC_000005.9:g.233740T>A	ClinGen:CA442691731	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1053C>A (p.Ile351=)	6389	SDHA	Likely benign	2126578352	RCV002170126\|RCV002398153;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233749	233749	233749	-
NM_004168.4(SDHA):c.1054C>T (p.Arg352Ter)	6389	SDHA	Pathogenic	746165168	RCV000232152\|RCV000567631\|RCV001329180\|RCV003316268;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|M	5	233750	233750	NC_000005.9:g.233750C>T	ClinGen:CA10582426	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1055G>A (p.Arg352Gln)	6389	SDHA	Conflicting interpretations of pathogenicity	199844384	RCV000411606\|RCV000563279\|RCV000765832\|RCV000463749\|RCV000498298\|RCV001153526\|RCV001153527\|RCV001153528\|RCV003475997;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506; MO	5	233751	233751	NC_000005.9:g.233751G>A	ClinGen:CA3173073	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1055G>T (p.Arg352Leu)	6389	SDHA	Uncertain significance	199844384	RCV001915420\|RCV003407918;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|	5	233751	233751	233751	-
NM_004168.4(SDHA):c.1056A>C (p.Arg352=)	6389	SDHA	Likely benign	779804839	RCV001482294\|RCV003298851;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233752	233752	233752	-
NM_004168.4(SDHA):c.1057G>A (p.Glu353Lys)	6389	SDHA	Uncertain significance	1328911130	RCV001301495\|RCV002411958;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233753	233753	233753	-
NM_004168.4(SDHA):c.1058A>C (p.Glu353Ala)	6389	SDHA	Uncertain significance	2126578405	RCV002019630;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233754	233754	233754	-
NM_004168.4(SDHA):c.1060G>A (p.Gly354Arg)	6389	SDHA	Uncertain significance	746611221	RCV001009814\|RCV002549304\|RCV003473563;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	233756	233756	5:g.233756G>A	-
NM_004168.4(SDHA):c.1060G>C (p.Gly354Arg)	6389	SDHA	Uncertain significance	746611221	RCV001302113;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	233756	233756	233756	-
NM_004168.4(SDHA):c.1061G>A (p.Gly354Glu)	6389	SDHA	Uncertain significance	2126578424	RCV002013131\|RCV003170518;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233757	233757	233757	-
NM_004168.4(SDHA):c.1062A>T (p.Gly354=)	6389	SDHA	Uncertain significance	-1	RCV003048786;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233758	233758		-
NM_004168.4(SDHA):c.1063A>T (p.Arg355Ter)	6389	SDHA	Pathogenic	-1	RCV003077360;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233759	233759	NC_000005.9:g.233759A>T	-
NM_004168.4(SDHA):c.1064G>T (p.Arg355Ile)	6389	SDHA	Uncertain significance	1735568346	RCV001324403;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233760	233760	233760	-
NM_004168.4(SDHA):c.1064G>C (p.Arg355Thr)	6389	SDHA	Uncertain significance	-1	RCV002898874;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233760	233760	NC_000005.9:g.233760G>C	-
NM_004168.4(SDHA):c.1064+1G>T	6389	SDHA	Likely pathogenic	1579402807	RCV000807030\|RCV002406799;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233761	233761	5:g.233761G>T	-
NM_004168.4(SDHA):c.1064+2T>A	6389	SDHA	Likely pathogenic	1553999072	RCV000525989\|RCV000569896\|RCV003476301;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	233762	233762	5:g.233762T>A	ClinGen:CA359013038	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1064+2T>G	6389	SDHA	Likely pathogenic	1553999072	RCV002048798;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	233762	233762	233762	-
NM_004168.4(SDHA):c.1064+3G>A	6389	SDHA	Conflicting interpretations of pathogenicity	1553999078	RCV000562188\|RCV001062134;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233763	233763	5:g.233763G>A	ClinGen:CA658657424	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1064+3G>C	6389	SDHA	Uncertain significance	-1	RCV002685823;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233763	233763	NC_000005.9:g.233763G>C	-
NM_004168.4(SDHA):c.1064+4C>T	6389	SDHA	Likely benign	768276870	RCV000225995\|RCV000575680\|RCV001722238;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	5	233764	233764	5:g.233764C>T	ClinGen:CA3173076	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1064+4C>A	6389	SDHA	Uncertain significance	768276870	RCV000559435;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	233764	233764	5:g.233764C>A	ClinGen:CA658657425	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1064+5GT[3]	6389	SDHA	Likely benign	2126578488	RCV002205860;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	233764	233765	233764	-
NM_004168.4(SDHA):c.1064+4C>G	6389	SDHA	Uncertain significance	-1	RCV002781314;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233764	233764	NC_000005.9:g.233764C>G	-
NM_004168.4(SDHA):c.1064+5G>A	6389	SDHA	Conflicting interpretations of pathogenicity	200021115	RCV000411854\|RCV000466048\|RCV000561515\|RCV001584106;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|	5	233765	233765	NC_000005.9:g.233765G>A	ClinGen:CA3173077	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1064+5G>C	6389	SDHA	Uncertain significance	200021115	RCV000471485\|RCV000565700;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	233765	233765	NC_000005.9:g.233765G>C	ClinGen:CA3173078	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1064+7G>T	6389	SDHA	Likely benign	2126578502	RCV001494572;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	233767	233767	233767	-
NM_004168.4(SDHA):c.1064+10A>G	6389	SDHA	Likely benign	773168516	RCV000470996;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	233770	233770	NC_000005.9:g.233770A>G	ClinGen:CA3173080	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1065-20A>G	6389	SDHA	Likely benign	-1	RCV002847468;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235239	235239	NC_000005.9:g.235239A>G	-
NM_004168.4(SDHA):c.1065-17_1065-15dup	6389	SDHA	Likely benign	-1	RCV002891116;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235239	235240	NC_000005.9:g.235242_235244dup	-
NM_004168.4(SDHA):c.1065-19T>C	6389	SDHA	Likely benign	1735682737	RCV002105310;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	235240	235240	235240	-
NM_004168.4(SDHA):c.1065-17G>A	6389	SDHA	Likely benign	1268945057	RCV002084808;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	235242	235242	235242	-
NM_004168.4(SDHA):c.1065-17G>C	6389	SDHA	Likely benign	1268945057	RCV002202627;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	235242	235242	235242	-
NM_004168.4(SDHA):c.1065-16T>C	6389	SDHA	Likely benign	765268601	RCV002089356;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	235243	235243	235243	-
NM_004168.4(SDHA):c.1065-12_1065-11del	6389	SDHA	Likely benign	-1	RCV002633507;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235246	235247	NC_000005.9:g.235247_235248del	-
NM_004168.4(SDHA):c.1065-10G>C	6389	SDHA	Likely benign	2126584071	RCV002145621;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235249	235249	235249	-
NM_004168.4(SDHA):c.1065-8C>G	6389	SDHA	Uncertain significance	-1	RCV002602968;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235251	235251	NC_000005.9:g.235251C>G	-
NM_004168.4(SDHA):c.1065-7T>C	6389	SDHA	Likely benign	1426933226	RCV002075869;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235252	235252	235252	-
NM_004168.4(SDHA):c.1065-6T>C	6389	SDHA	Likely benign	1579406151	RCV001402307;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235253	235253	5:g.235253T>C	-
NM_004168.4(SDHA):c.1065-5A>G	6389	SDHA	Likely benign	1579406152	RCV000922838;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235254	235254	5:g.235254A>G	-
NM_004168.4(SDHA):c.1065-4C>A	6389	SDHA	Likely benign	575007678	RCV000543416\|RCV000573469;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235255	235255	NC_000005.9:g.235255C>A	ClinGen:CA3173107	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1065A>G (p.Arg355=)	6389	SDHA	Uncertain significance	2126584114	RCV002004361;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235259	235259	235259	-
NM_004168.4(SDHA):c.1069T>C (p.Cys357Arg)	6389	SDHA	Uncertain significance	1735685410	RCV001229481;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235263	235263	5:g.235263T>C	-
NM_004168.4(SDHA):c.1070G>A (p.Cys357Tyr)	6389	SDHA	Uncertain significance	1560996433	RCV000704504\|RCV002422592;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235264	235264	5:g.235264G>A	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1071T>C (p.Cys357=)	6389	SDHA	Likely benign	1553999410	RCV000535339;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	235265	235265	5:g.235265T>C	ClinGen:CA442691922	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1073G>A (p.Gly358Asp)	6389	SDHA	Uncertain significance	-1	RCV002417113\|RCV003097419;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235267	235267	235267	-
NM_004168.4(SDHA):c.1074C>T (p.Gly358=)	6389	SDHA	Likely benign	1421396049	RCV001449395\|RCV001528612\|RCV002421015;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235268	235268	235268	-
NM_004168.4(SDHA):c.1075C>T (p.Pro359Ser)	6389	SDHA	Uncertain significance	758817818	RCV001237755;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235269	235269	5:g.235269C>T	-
NM_004168.4(SDHA):c.1078G>A (p.Glu360Lys)	6389	SDHA	Uncertain significance	766779919	RCV000649417\|RCV002499109\|RCV002422379\|RCV003472042;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO	5	235272	235272	NC_000005.9:g.235272G>A	ClinGen:CA3173109	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1083A>G (p.Lys361=)	6389	SDHA	Likely benign	1579406203	RCV001418893\|RCV002427312;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235277	235277	5:g.235277A>G	-
NM_004168.4(SDHA):c.1083_1084insTCT (p.Lys361_Asp362insSer)	6389	SDHA	Uncertain significance	1735687291	RCV001205713;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235277	235278	5:g.235277_235278insTCT	-
NM_004168.4(SDHA):c.1083A>C (p.Lys361Asn)	6389	SDHA	Uncertain significance	-1	RCV003050212;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235277	235277	NC_000005.9:g.235277A>C	-
NM_004168.4(SDHA):c.1084G>T (p.Asp362Tyr)	6389	SDHA	Uncertain significance	2126584224	RCV001360847;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235278	235278	235278	-
NM_004168.4(SDHA):c.1086T>C (p.Asp362=)	6389	SDHA	Likely benign	2126584236	RCV001409209;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235280	235280	235280	-
NM_004168.4(SDHA):c.1087C>G (p.His363Asp)	6389	SDHA	Uncertain significance	1553999417	RCV000649392;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235281	235281	NC_000005.9:g.235281C>G	ClinGen:CA359013427	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1087C>T (p.His363Tyr)	6389	SDHA	Uncertain significance	1553999417	RCV001298787;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235281	235281	235281	-
NM_004168.4(SDHA):c.1088A>G (p.His363Arg)	6389	SDHA	Uncertain significance	-1	RCV002297769;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235282	235282	235282	-
NM_004168.4(SDHA):c.1089C>T (p.His363=)	6389	SDHA	Benign/Likely benign	368488126	RCV000423532\|RCV000473235\|RCV001009877;	N	MedGen:CN169374\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235283	235283	5:g.235283C>T	ClinGen:CA3173110	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1089C>A (p.His363Gln)	6389	SDHA	Uncertain significance	368488126	RCV001349753;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235283	235283	235283	-
NM_004168.4(SDHA):c.1090G>A (p.Val364Ile)	6389	SDHA	Uncertain significance	372738835	RCV000463908\|RCV000561241;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235284	235284	NC_000005.9:g.235284G>A	ClinGen:CA3173111	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1090G>C (p.Val364Leu)	6389	SDHA	Uncertain significance	372738835	RCV000535289;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	235284	235284	NC_000005.9:g.235284G>C	ClinGen:CA359013435	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1092C>T (p.Val364=)	6389	SDHA	Conflicting interpretations of pathogenicity	886060515	RCV000260734\|RCV000316002\|RCV000355512\|RCV002446606;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506\|MONDO:MONDO:0017366,MedGen:C1708353, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235286	235286	NC_000005.9:g.235286C>T	ClinGen:CA10620256	C0023264 256000 Leigh syndrome;
NM_004168.4(SDHA):c.1092C>G (p.Val364=)	6389	SDHA	Likely benign	886060515	RCV000977019;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235286	235286	5:g.235286C>G	-
NM_004168.4(SDHA):c.1096C>T (p.Leu366=)	6389	SDHA	Likely benign	1305056679	RCV001505608;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235290	235290	235290	-
NM_004168.4(SDHA):c.1098G>C (p.Leu366=)	6389	SDHA	Likely benign	1346189100	RCV001405764\|RCV003170024;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235292	235292	235292	-
NM_004168.4(SDHA):c.1099C>G (p.Gln367Glu)	6389	SDHA	Uncertain significance	780941330	RCV000806830\|RCV003166259;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235293	235293	5:g.235293C>G	-
NM_004168.4(SDHA):c.1103_1105del (p.Leu368del)	6389	SDHA	Uncertain significance	1735689664	RCV001044195;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	235295	235297	5:g.235295_235297del	-
NM_004168.4(SDHA):c.1101G>A (p.Gln367=)	6389	SDHA	Likely benign	-1	RCV002433073\|RCV003101920;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235295	235295		-
NM_004168.4(SDHA):c.1103T>C (p.Leu368Pro)	6389	SDHA	Uncertain significance	2126584397	RCV002046505;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	235297	235297	235297	-
NM_004168.4(SDHA):c.1104G>A (p.Leu368=)	6389	SDHA	Likely benign	2126584401	RCV001417912\|RCV002456674;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235298	235298	235298	-
NM_004168.4(SDHA):c.1105C>T (p.His369Tyr)	6389	SDHA	Uncertain significance	2126584410	RCV002002578\|RCV002425349;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235299	235299	235299	-
NM_004168.4(SDHA):c.1107C>A (p.His369Gln)	6389	SDHA	Uncertain significance	1268877544	RCV000649425\|RCV002458124;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235301	235301	NC_000005.9:g.235301C>A	ClinGen:CA359013470	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1108C>A (p.His370Asn)	6389	SDHA	Uncertain significance	1060503704	RCV000464973\|RCV003168870;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235302	235302	NC_000005.9:g.235302C>A	ClinGen:CA16611954	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1108C>T (p.His370Tyr)	6389	SDHA	Uncertain significance	1060503704	RCV002021688;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235302	235302	235302	-
NM_004168.4(SDHA):c.1110C>T (p.His370=)	6389	SDHA	Likely benign	1579406318	RCV001486585\|RCV002427162;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235304	235304	5:g.235304C>T	-
NM_004168.4(SDHA):c.1111C>T (p.Leu371=)	6389	SDHA	Likely benign	1735690368	RCV001462106;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	235305	235305	5:g.235305C>T	-
NM_004168.4(SDHA):c.1111C>G (p.Leu371Val)	6389	SDHA	Uncertain significance	1735690368	RCV001963487;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	235305	235305	235305	-
NM_004168.4(SDHA):c.1113A>G (p.Leu371=)	6389	SDHA	Likely benign	2126584480	RCV001464124;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235307	235307	235307	-
NM_004168.4(SDHA):c.1115C>G (p.Pro372Arg)	6389	SDHA	Uncertain significance	141493530	RCV000477582\|RCV000575145\|RCV001775824\|RCV002481482\|RCV003147470;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011	5	235309	235309	NC_000005.9:g.235309C>G	ClinGen:CA3173113	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1115C>T (p.Pro372Leu)	6389	SDHA	Uncertain significance	141493530	RCV001221573\|RCV002436856;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235309	235309	5:g.235309C>T	-
NM_004168.4(SDHA):c.1116T>G (p.Pro372=)	6389	SDHA	Likely benign	1735691014	RCV002088573\|RCV002434474;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235310	235310	235310	-
NM_004168.4(SDHA):c.1119A>G (p.Pro373=)	6389	SDHA	Likely benign	1428505412	RCV000866761\|RCV002434092;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235313	235313	5:g.235313A>G	-
NM_004168.4(SDHA):c.1119A>C (p.Pro373=)	6389	SDHA	Likely benign	1428505412	RCV000871881\|RCV002434125;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235313	235313	5:g.235313A>C	-
NM_004168.4(SDHA):c.1122G>T (p.Glu374Asp)	6389	SDHA	Uncertain significance	377283167	RCV000815226\|RCV001569248\|RCV002433982;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235316	235316	5:g.235316G>T	-
NM_004168.4(SDHA):c.1123C>T (p.Gln375Ter)	6389	SDHA	Pathogenic	1735691933	RCV001063568\|RCV002436649;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235317	235317	5:g.235317C>T	-
NM_004168.4(SDHA):c.1126C>T (p.Leu376=)	6389	SDHA	Likely benign	1579406388	RCV000926983\|RCV002445036;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235320	235320	5:g.235320C>T	-
NM_004168.4(SDHA):c.1127T>C (p.Leu376Pro)	6389	SDHA	Uncertain significance	1433477205	RCV000821732\|RCV001017412\|RCV001551721\|RCV003447567;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011	5	235321	235321	5:g.235321T>C	-
NM_004168.4(SDHA):c.1129G>C (p.Ala377Pro)	6389	SDHA	Uncertain significance	1735692451	RCV001309196;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235323	235323	235323	-
NM_004168.4(SDHA):c.1130C>A (p.Ala377Asp)	6389	SDHA	Uncertain significance	1553999443	RCV000547611;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	235324	235324	5:g.235324C>A	ClinGen:CA359013518	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1130C>T (p.Ala377Val)	6389	SDHA	Uncertain significance	1553999443	RCV001317575\|RCV002322230;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235324	235324	235324	-
NM_004168.4(SDHA):c.1131C>T (p.Ala377=)	6389	SDHA	Likely benign	2126584661	RCV002175720\|RCV002325690;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235325	235325	235325	-
NM_004168.4(SDHA):c.1132A>G (p.Thr378Ala)	6389	SDHA	Uncertain significance	1224187912	RCV000820717\|RCV002442752;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235326	235326	5:g.235326A>G	-
NM_004168.4(SDHA):c.1133dup (p.Arg379fs)	6389	SDHA	Pathogenic	-1	RCV003054135;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235326	235327	NC_000005.9:g.235327dup	-
NM_004168.4(SDHA):c.1133C>T (p.Thr378Met)	6389	SDHA	Conflicting interpretations of pathogenicity	777420907	RCV000649406\|RCV001009958;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235327	235327	5:g.235327C>T	ClinGen:CA3173115	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1134G>A (p.Thr378=)	6389	SDHA	Likely benign	370002515	RCV000461455\|RCV001009968;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235328	235328	NC_000005.9:g.235328G>A	ClinGen:CA16612055	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1134G>C (p.Thr378=)	6389	SDHA	Likely benign	370002515	RCV002216505\|RCV002324549;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235328	235328	235328	-
NM_004168.4(SDHA):c.1135C>T (p.Arg379Cys)	6389	SDHA	Uncertain significance	749309213	RCV000214185\|RCV000459361\|RCV000514432;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MedGen:C3661900	5	235329	235329	5:g.235329C>T	ClinGen:CA3173116	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1136G>A (p.Arg379His)	6389	SDHA	Uncertain significance	770719847	RCV000477473\|RCV001009945\|RCV002254698;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235330	235330	NC_000005.9:g.235330G>A	ClinGen:CA3173117	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1136G>T (p.Arg379Leu)	6389	SDHA	Uncertain significance	770719847	RCV002048420;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235330	235330	235330	-
NM_004168.4(SDHA):c.1138del (p.Leu380fs)	6389	SDHA	Pathogenic	-1	RCV002791318;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235331	235331	NC_000005.9:g.235332del	-
NM_004168.4(SDHA):c.1138C>A (p.Leu380Met)	6389	SDHA	Uncertain significance	1735694280	RCV001301577;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235332	235332	235332	-
NM_004168.4(SDHA):c.1138C>T (p.Leu380=)	6389	SDHA	Likely benign	-1	RCV002801739;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235332	235332		-
NM_004168.4(SDHA):c.1139T>G (p.Leu380Arg)	6389	SDHA	Uncertain significance	-1	RCV003042606;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235333	235333	NC_000005.9:g.235333T>G	-
NM_004168.4(SDHA):c.1140G>A (p.Leu380=)	6389	SDHA	Likely benign	146348714	RCV000473616\|RCV000831510\|RCV002455906;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235334	235334	NC_000005.9:g.235334G>A	ClinGen:CA16611883	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1140G>C (p.Leu380=)	6389	SDHA	Likely benign	146348714	RCV000871043\|RCV002332820;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235334	235334	5:g.235334G>C	-
NM_004168.4(SDHA):c.1141C>G (p.Pro381Ala)	6389	SDHA	Uncertain significance	1735694889	RCV001294635;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235335	235335	235335	-
NM_004168.4(SDHA):c.1144_1149dup (p.Gly382_Ile383dup)	6389	SDHA	Uncertain significance	2126584776	RCV002022191;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	235336	235337	235336	-
NM_004168.4(SDHA):c.1143T>C (p.Pro381=)	6389	SDHA	Likely benign	1735695108	RCV001457382\|RCV002456774;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235337	235337	235337	-
NM_004168.4(SDHA):c.1144G>A (p.Gly382Ser)	6389	SDHA	Uncertain significance	1272640628	RCV000649451\|RCV003162972;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235338	235338	NC_000005.9:g.235338G>A	ClinGen:CA359013541	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1145G>A (p.Gly382Asp)	6389	SDHA	Uncertain significance	373067620	RCV001963325;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235339	235339	235339	-
NM_004168.4(SDHA):c.1146C>A (p.Gly382=)	6389	SDHA	Likely benign	768947225	RCV000872236\|RCV002454016;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235340	235340	5:g.235340C>A	-
NM_004168.4(SDHA):c.1147A>G (p.Ile383Val)	6389	SDHA	Uncertain significance	2126584806	RCV001365720;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235341	235341	235341	-
NM_004168.4(SDHA):c.1150T>G (p.Ser384Ala)	6389	SDHA	Uncertain significance	776888362	RCV000528318\|RCV000765833\|RCV002350352;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506; MOND	5	235344	235344	5:g.235344T>G	ClinGen:CA3173121	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1151C>G (p.Ser384Ter)	6389	SDHA	Pathogenic	151170408	RCV000221764\|RCV000810033\|RCV001799638\|RCV002307451\|RCV002254689;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|Human Phenotype Ontology:HP:0100723,MONDO:MONDO:0011719,MeSH:D0	5	235345	235345	NC_000005.9:g.235345C>G	ClinGen:CA3173122	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1152A>T (p.Ser384=)	6389	SDHA	Likely benign	2126584840	RCV001429506\|RCV002350841;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235346	235346	235346	-
NM_004168.4(SDHA):c.1155G>A (p.Glu385=)	6389	SDHA	Likely benign	765356526	RCV000565438\|RCV000867238;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235349	235349	5:g.235349G>A	ClinGen:CA3173123	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1156A>G (p.Thr386Ala)	6389	SDHA	Uncertain significance	1553999461	RCV000649410;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235350	235350	NC_000005.9:g.235350A>G	ClinGen:CA359013566	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1157C>T (p.Thr386Ile)	6389	SDHA	Uncertain significance	773218958	RCV000649424\|RCV003162971;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235351	235351	NC_000005.9:g.235351C>T	ClinGen:CA3173124	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1158A>C (p.Thr386=)	6389	SDHA	Likely benign	2126584886	RCV001396966;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235352	235352	235352	-
NM_004168.4(SDHA):c.1159G>A (p.Ala387Thr)	6389	SDHA	Uncertain significance	2126584893	RCV001931110;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	235353	235353	235353	-
NM_004168.4(SDHA):c.1161C>T (p.Ala387=)	6389	SDHA	Likely benign	-1	RCV003084128;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235355	235355		-
NM_004168.4(SDHA):c.1162A>T (p.Met388Leu)	6389	SDHA	Uncertain significance	1579406553	RCV001981606\|RCV003339852;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235356	235356	235356	-
NM_004168.4(SDHA):c.1163T>C (p.Met388Thr)	6389	SDHA	Uncertain significance	1419241279	RCV001983131;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235357	235357	235357	-
NM_004168.4(SDHA):c.1165A>G (p.Ile389Val)	6389	SDHA	Uncertain significance	1316310818	RCV001337806\|RCV002322268;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235359	235359	235359	-
NM_004168.4(SDHA):c.1167C>T (p.Ile389=)	6389	SDHA	Likely benign	2126584963	RCV002220838\|RCV003339914;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235361	235361	235361	-
NM_004168.4(SDHA):c.1170C>T (p.Phe390=)	6389	SDHA	Benign	35277230	RCV000118312\|RCV000163257\|RCV000285173\|RCV000321449\|RCV000379943\|RCV000470511\|RCV003315676;	N	MedGen:CN169374\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0017366,MedGen:C1708353, Orphanet:29072\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:50	5	235364	235364	5:g.235364C>T	ClinGen:CA155144	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1170C>A (p.Phe390Leu)	6389	SDHA	Uncertain significance	35277230	RCV001227291;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235364	235364	5:g.235364C>A	-
NM_004168.4(SDHA):c.1171G>T (p.Ala391Ser)	6389	SDHA	Uncertain significance	376597185	RCV000536076;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235365	235365	5:g.235365G>T	ClinGen:CA359013600	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1171G>A (p.Ala391Thr)	6389	SDHA	Uncertain significance	376597185	RCV000649414\|RCV002331241\|RCV003472041;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	235365	235365	NC_000005.9:g.235365G>A	ClinGen:CA3173126	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1172C>G (p.Ala391Gly)	6389	SDHA	Uncertain significance	-1	RCV002332241\|RCV003094655;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235366	235366	235366	-
NM_004168.4(SDHA):c.1173T>C (p.Ala391=)	6389	SDHA	Likely benign	1579406627	RCV000918088;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235367	235367	5:g.235367T>C	-
NM_004168.4(SDHA):c.1176C>T (p.Gly392=)	6389	SDHA	Likely benign	1041950	RCV000461984\|RCV000561058\|RCV002475895;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	5	235370	235370	NC_000005.9:g.235370C>T	ClinGen:CA3173128	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1176C>A (p.Gly392=)	6389	SDHA	Likely benign	1041950	RCV002164334;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235370	235370	235370	-
NM_004168.4(SDHA):c.1177G>T (p.Val393Leu)	6389	SDHA	Conflicting interpretations of pathogenicity	372989971	RCV000548710\|RCV003139851\|RCV001329181\|RCV002258966;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MedGen:C3661900\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672,O	5	235371	235371	NC_000005.9:g.235371G>T	ClinGen:CA3173129	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1177G>A (p.Val393Met)	6389	SDHA	Conflicting interpretations of pathogenicity	372989971	RCV001010145\|RCV001156141\|RCV001156142\|RCV001156140\|RCV001238661\|RCV003432990;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0017366,MedGen:C1708353, Orphanet:29072\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:01	5	235371	235371	5:g.235371G>A	-
NM_004168.4(SDHA):c.1177G>C (p.Val393Leu)	6389	SDHA	Uncertain significance	372989971	RCV001038411;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	235371	235371	5:g.235371G>C	-
NM_004168.4(SDHA):c.1182C>T (p.Asp394=)	6389	SDHA	Likely benign	377317558	RCV000232577\|RCV002338728\|RCV003316269;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235376	235376	5:g.235376C>T	ClinGen:CA3173131	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1182C>A (p.Asp394Glu)	6389	SDHA	Uncertain significance	-1	RCV003042586;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235376	235376	NC_000005.9:g.235376C>A	-
NM_004168.4(SDHA):c.1183G>T (p.Val395Phe)	6389	SDHA	Uncertain significance	748683825	RCV000524573\|RCV002330948;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235377	235377	NC_000005.9:g.235377G>T	ClinGen:CA359013622	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1183G>A (p.Val395Ile)	6389	SDHA	Uncertain significance	748683825	RCV000649396\|RCV001788309\|RCV002334184\|RCV003472039;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|	5	235377	235377	NC_000005.9:g.235377G>A	ClinGen:CA3173132	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1185C>G (p.Val395=)	6389	SDHA	Likely benign	2126585130	RCV001456990;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	235379	235379	235379	-
NM_004168.4(SDHA):c.1187C>T (p.Thr396Met)	6389	SDHA	Uncertain significance	757251714	RCV000571028\|RCV000706201;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235381	235381	NC_000005.9:g.235381C>T	ClinGen:CA3173133	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1188G>A (p.Thr396=)	6389	SDHA	Conflicting interpretations of pathogenicity	778667374	RCV000541698\|RCV001010227\|RCV001156143\|RCV001156144\|RCV001157830;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|M	5	235382	235382	5:g.235382G>A	ClinGen:CA3173134	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1190A>G (p.Lys397Arg)	6389	SDHA	Uncertain significance	745798689	RCV000561376\|RCV001853800;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235384	235384	5:g.235384A>G	ClinGen:CA359013635	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1190A>C (p.Lys397Thr)	6389	SDHA	Uncertain significance	745798689	RCV001342100\|RCV003294348;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235384	235384	235384	-
NM_004168.4(SDHA):c.1191G>C (p.Lys397Asn)	6389	SDHA	Uncertain significance	1035794713	RCV000817414\|RCV001843554\|RCV002336693;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0031006,MedGen:C5543254,OMIM:619259\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235385	235385	5:g.235385G>C	-
NM_004168.4(SDHA):c.1194G>A (p.Glu398=)	6389	SDHA	Likely benign	1735703214	RCV002086013\|RCV003339921;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235388	235388	235388	-
NM_004168.4(SDHA):c.1195C>T (p.Pro399Ser)	6389	SDHA	Uncertain significance	2126585242	RCV001963848;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	235389	235389	235389	-
NM_004168.4(SDHA):c.1196C>T (p.Pro399Leu)	6389	SDHA	Uncertain significance	878854625	RCV000226409\|RCV000663203\|RCV001010179;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235390	235390	5:g.235390C>T	ClinGen:CA10582427	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1196C>A (p.Pro399Gln)	6389	SDHA	Uncertain significance	878854625	RCV000570997\|RCV000658024\|RCV001221392;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235390	235390	NC_000005.9:g.235390C>A	ClinGen:CA359013648
NM_004168.4(SDHA):c.1197G>A (p.Pro399=)	6389	SDHA	Likely benign	771919335	RCV000474220\|RCV002341120;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235391	235391	NC_000005.9:g.235391G>A	ClinGen:CA3173136	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1197G>T (p.Pro399=)	6389	SDHA	Likely benign	771919335	RCV000877457\|RCV002336858;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235391	235391	5:g.235391G>T	-
NM_004168.4(SDHA):c.1199T>A (p.Ile400Asn)	6389	SDHA	Uncertain significance	876660886	RCV000216966\|RCV001041220;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235393	235393	5:g.235393T>A	ClinGen:CA10578629	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1200C>T (p.Ile400=)	6389	SDHA	Likely benign	748383004	RCV001413784\|RCV002350797;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235394	235394	235394	-
NM_004168.4(SDHA):c.1201C>T (p.Pro401Ser)	6389	SDHA	Uncertain significance	1560996818	RCV001301498\|RCV003166697;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235395	235395	235395	-
NM_004168.4(SDHA):c.1203T>C (p.Pro401=)	6389	SDHA	Likely benign	1553999484	RCV000649484\|RCV002343345;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235397	235397	5:g.235397T>C	ClinGen:CA442692008	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1203T>G (p.Pro401=)	6389	SDHA	Likely benign	-1	RCV002351946\|RCV003096789;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235397	235397		-
NM_004168.4(SDHA):c.1204G>C (p.Val402Leu)	6389	SDHA	Uncertain significance	2126585344	RCV001914109\|RCV002344046;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235398	235398	235398	-
NM_004168.4(SDHA):c.1205T>G (p.Val402Gly)	6389	SDHA	Uncertain significance	2126585353	RCV001359427;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235399	235399	235399	-
NM_004168.4(SDHA):c.1206C>T (p.Val402=)	6389	SDHA	Likely benign	1183961449	RCV000555221\|RCV002350353;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235400	235400	NC_000005.9:g.235400C>T	ClinGen:CA442692010	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1206C>G (p.Val402=)	6389	SDHA	Likely benign	-1	RCV002598619;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235400	235400		-
NM_004168.4(SDHA):c.1207C>T (p.Leu403Phe)	6389	SDHA	Uncertain significance	-1	RCV002706300;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235401	235401	NC_000005.9:g.235401C>T	-
NM_004168.4(SDHA):c.1209C>A (p.Leu403=)	6389	SDHA	Likely benign	2126585389	RCV002197842\|RCV002346384;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235403	235403	235403	-
NM_004168.4(SDHA):c.1209C>T (p.Leu403=)	6389	SDHA	Likely benign	-1	RCV002359621\|RCV003103229;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235403	235403		-
NM_004168.4(SDHA):c.1210C>T (p.Pro404Ser)	6389	SDHA	Uncertain significance	769936006	RCV001299758;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235404	235404	235404	-
NM_004168.4(SDHA):c.1212C>A (p.Pro404=)	6389	SDHA	Likely benign	1579406812	RCV001462181\|RCV002354729;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235406	235406	5:g.235406C>A	-
NM_004168.4(SDHA):c.1214C>A (p.Thr405Asn)	6389	SDHA	Uncertain significance	1553999491	RCV000526540\|RCV002358582;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235408	235408	5:g.235408C>A	ClinGen:CA359013681	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1214C>T (p.Thr405Ile)	6389	SDHA	Uncertain significance	-1	RCV002295255;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235408	235408	235408	-
NM_004168.4(SDHA):c.1215C>T (p.Thr405=)	6389	SDHA	Likely benign	762888704	RCV000229253\|RCV001010329;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235409	235409	5:g.235409C>T	ClinGen:CA3173141	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1215C>A (p.Thr405=)	6389	SDHA	Conflicting interpretations of pathogenicity	762888704	RCV001066932\|RCV002355087;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235409	235409	5:g.235409C>A	-
NM_004168.4(SDHA):c.1216G>A (p.Val406Met)	6389	SDHA	Uncertain significance	1258201485	RCV000562001\|RCV000649439;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235410	235410	5:g.235410G>A	ClinGen:CA359013684	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1220A>G (p.His407Arg)	6389	SDHA	Conflicting interpretations of pathogenicity	374087393	RCV001010388\|RCV001862768;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235414	235414	5:g.235414A>G	-
NM_004168.4(SDHA):c.1220A>T (p.His407Leu)	6389	SDHA	Uncertain significance	374087393	RCV001318441;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235414	235414	235414	-
NM_004168.4(SDHA):c.1221T>C (p.His407=)	6389	SDHA	Likely benign	2126585516	RCV002175136;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	235415	235415	235415	-
NM_004168.4(SDHA):c.1225A>C (p.Asn409His)	6389	SDHA	Uncertain significance	1404377989	RCV000539132\|RCV001010422;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235419	235419	5:g.235419A>C	ClinGen:CA359013704	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1225A>T (p.Asn409Tyr)	6389	SDHA	Uncertain significance	-1	RCV002765474;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235419	235419	NC_000005.9:g.235419A>T	-
NM_004168.4(SDHA):c.1227C>T (p.Asn409=)	6389	SDHA	Likely benign	2126585562	RCV001457627\|RCV002377768;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235421	235421	235421	-
NM_004168.4(SDHA):c.1228A>G (p.Met410Val)	6389	SDHA	Uncertain significance	876658852	RCV000213886\|RCV001312342;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235422	235422	5:g.235422A>G	ClinGen:CA10578630	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1229T>C (p.Met410Thr)	6389	SDHA	Uncertain significance	1553999505	RCV000556000;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	235423	235423	NC_000005.9:g.235423T>C	ClinGen:CA359013716	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1230G>C (p.Met410Ile)	6389	SDHA	Uncertain significance	1735707028	RCV001325014;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235424	235424	235424	-
NM_004168.4(SDHA):c.1231G>A (p.Gly411Ser)	6389	SDHA	Uncertain significance	2126585602	RCV001897788;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	235425	235425	235425	-
NM_004168.4(SDHA):c.1233C>T (p.Gly411=)	6389	SDHA	Likely benign	376530094	RCV000468789\|RCV000569519\|RCV001821384;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN169374	5	235427	235427	NC_000005.9:g.235427C>T	ClinGen:CA3173143	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1233C>A (p.Gly411=)	6389	SDHA	Likely benign	376530094	RCV000532183\|RCV002377145;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235427	235427	5:g.235427C>A	ClinGen:CA3173144	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1234G>T (p.Gly412Cys)	6389	SDHA	Uncertain significance	768055345	RCV000233529\|RCV000570013\|RCV003475065;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	235428	235428	NC_000005.9:g.235428G>T	ClinGen:CA3173146	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1234G>A (p.Gly412Ser)	6389	SDHA	Uncertain significance	768055345	RCV000544502\|RCV000564411\|RCV002291665\|RCV003451191\|RCV003319374\|RCV003476306;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|	5	235428	235428	NC_000005.9:g.235428G>A	ClinGen:CA3173145	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1236C>T (p.Gly412=)	6389	SDHA	Likely benign	-1	RCV002863274;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235430	235430		-
NM_004168.4(SDHA):c.1240C>T (p.Pro414Ser)	6389	SDHA	Uncertain significance	1735708028	RCV002017046\|RCV002386906;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235434	235434	235434	-
NM_004168.4(SDHA):c.1240C>G (p.Pro414Ala)	6389	SDHA	Uncertain significance	1735708028	RCV002035714;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235434	235434	235434	-
NM_004168.4(SDHA):c.1241CCA[1] (p.Thr415del)	6389	SDHA	Uncertain significance	2126585682	RCV001976281;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235435	235437	235434	-
NM_004168.4(SDHA):c.1242C>T (p.Pro414=)	6389	SDHA	Likely benign	777306884	RCV000227375\|RCV000987495\|RCV001010504\|RCV003437020;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|M	5	235436	235436	5:g.235436C>T	ClinGen:CA3173147	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1245dup (p.Asn416fs)	6389	SDHA	Pathogenic	2126585710	RCV001893983;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235437	235438	235437	-
NM_004168.4(SDHA):c.1243A>G (p.Thr415Ala)	6389	SDHA	Uncertain significance	2126585699	RCV001917056;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235437	235437	235437	-
NM_004168.4(SDHA):c.1245C>G (p.Thr415=)	6389	SDHA	Likely benign	2126585715	RCV002203900;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	235439	235439	235439	-
NM_004168.4(SDHA):c.1246A>G (p.Asn416Asp)	6389	SDHA	Uncertain significance	1355851620	RCV000796276\|RCV001010533\|RCV003472347;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	235440	235440	5:g.235440A>G	-
NM_004168.4(SDHA):c.1247A>T (p.Asn416Ile)	6389	SDHA	Uncertain significance	1409603646	RCV001216224\|RCV002393508;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235441	235441	5:g.235441A>T	-
NM_004168.4(SDHA):c.1247A>G (p.Asn416Ser)	6389	SDHA	Uncertain significance	-1	RCV002815280;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235441	235441	NC_000005.9:g.235441A>G	-
NM_004168.4(SDHA):c.1250A>G (p.Tyr417Cys)	6389	SDHA	Uncertain significance	528628545	RCV000531820\|RCV002413603;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235444	235444	NC_000005.9:g.235444A>G	ClinGen:CA3173148	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1252A>G (p.Lys418Glu)	6389	SDHA	Uncertain significance	-1	RCV002303880\|RCV002409646\|RCV003475333;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	235446	235446	235446	-
NM_004168.4(SDHA):c.1255G>A (p.Gly419Arg)	6389	SDHA	Uncertain significance	1735709331	RCV001237926\|RCV001799749\|RCV002411878\|RCV003473815;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|Human Phenotype Ontology:HP:0100723,MONDO:MONDO:0011719,MeSH:D046152,MedGen:C0238198,OMIM:606764, Orphanet:44890\|MONDO:MONDO:0015	5	235449	235449	5:g.235449G>A	-
NM_004168.4(SDHA):c.1257G>A (p.Gly419=)	6389	SDHA	Likely benign	753410011	RCV000474023\|RCV001010368;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235451	235451	NC_000005.9:g.235451G>A	ClinGen:CA3173149	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1257G>T (p.Gly419=)	6389	SDHA	Likely benign	753410011	RCV002095586\|RCV002423351;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235451	235451	235451	-
NM_004168.4(SDHA):c.1258C>T (p.Gln420Ter)	6389	SDHA	Pathogenic	1579407009	RCV000792416\|RCV003453639;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235452	235452	5:g.235452C>T	-
NM_004168.4(SDHA):c.1259A>G (p.Gln420Arg)	6389	SDHA	Uncertain significance	1735709829	RCV001342075\|RCV002412074;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235453	235453	235453	-
NM_004168.4(SDHA):c.1260G>A (p.Gln420=)	6389	SDHA	Uncertain significance	-1	RCV002412599\|RCV003099922;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235454	235454		-
NM_004168.4(SDHA):c.1260+1G>A	6389	SDHA	Likely pathogenic	1735710012	RCV001052460\|RCV003473649;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	235455	235455	5:g.235455G>A	-
NM_004168.4(SDHA):c.1260+2T>A	6389	SDHA	Likely pathogenic	1735710103	RCV001055477\|RCV003238290;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MedGen:C3661900	5	235456	235456	5:g.235456T>A	-
NM_004168.4(SDHA):c.1260+3G>T	6389	SDHA	Uncertain significance	2126585827	RCV001371369;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	235457	235457	235457	-
NM_004168.4(SDHA):c.1260+4A>G	6389	SDHA	Uncertain significance	1060503702	RCV000456569\|RCV002429555;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	235458	235458	NC_000005.9:g.235458A>G	ClinGen:CA16611960	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1260+6G>A	6389	SDHA	Uncertain significance	2126585843	RCV001982649;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235460	235460	235460	-
NM_004168.4(SDHA):c.1260+8T>A	6389	SDHA	Likely benign	1325588204	RCV000649474;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235462	235462	NC_000005.9:g.235462T>A	ClinGen:CA557397594	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1260+8T>G	6389	SDHA	Likely benign	-1	RCV002604008;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235462	235462	NC_000005.9:g.235462T>G	-
NM_004168.4(SDHA):c.1260+9G>T	6389	SDHA	Likely benign	1060505003	RCV000468116;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	235463	235463	NC_000005.9:g.235463G>T	ClinGen:CA16611884	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1260+10C>T	6389	SDHA	Likely benign	1300688046	RCV002167539;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235464	235464	235464	-
NM_004168.4(SDHA):c.1260+12G>A	6389	SDHA	Likely benign	-1	RCV002592955;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235466	235466	NC_000005.9:g.235466G>A	-
NM_004168.4(SDHA):c.1260+13G>T	6389	SDHA	Benign/Likely benign	185239026	RCV000605596\|RCV002066547;	N	MedGen:CN169374\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	235467	235467	5:g.235467G>T	ClinGen:CA3173150	CN169374 not specified;
NM_004168.4(SDHA):c.1260+14C>T	6389	SDHA	Likely benign	1237313111	RCV002200675;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235468	235468	235468	-
NM_004168.4(SDHA):c.1260+15T>C	6389	SDHA	Likely benign	778457213	RCV002176777;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235469	235469	235469	-
NM_004168.4(SDHA):c.1260+16C>T	6389	SDHA	Likely benign	2126585898	RCV002168426;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235470	235470	235470	-
NM_004168.4(SDHA):c.1260+17C>G	6389	SDHA	Likely benign	750384205	RCV002116772;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	235471	235471	235471	-
NM_004168.4(SDHA):c.1260+17C>T	6389	SDHA	Likely benign	750384205	RCV002166528;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235471	235471	235471	-
NM_004168.4(SDHA):c.1260+18T>A	6389	SDHA	Likely benign	-1	RCV003053226;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235472	235472	NC_000005.9:g.235472T>A	-
NM_004168.4(SDHA):c.1260+18T>C	6389	SDHA	Likely benign	-1	RCV002863476;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235472	235472	NC_000005.9:g.235472T>C	-
NM_004168.4(SDHA):c.1260+23dup	6389	SDHA	Benign	-1	RCV003031103;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235472	235473	NC_000005.9:g.235477dup	-
NM_004168.4(SDHA):c.1260+19C>T	6389	SDHA	Likely benign	1735711604	RCV002112501;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235473	235473	235473	-
NM_004168.4(SDHA):c.1260+20C>T	6389	SDHA	Likely benign	779828602	RCV002171169;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	235474	235474	235474	-
NM_004168.4(SDHA):c.1261-19G>T	6389	SDHA	Likely benign	-1	RCV003038635;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236524	236524	NC_000005.9:g.236524G>T	-
NM_004168.4(SDHA):c.1261-17A>T	6389	SDHA	Likely benign	-1	RCV002583541;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236526	236526	NC_000005.9:g.236526A>T	-
NM_004168.4(SDHA):c.1261-16A>T	6389	SDHA	Likely benign	1170006255	RCV002149782;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	236527	236527	236527	-
NM_004168.4(SDHA):c.1261-11C>G	6389	SDHA	Likely benign	2126589164	RCV002168540;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236532	236532	236532	-
NM_004168.4(SDHA):c.1261-10C>G	6389	SDHA	Likely benign	1579409244	RCV001408277;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236533	236533	5:g.236533C>G	-
NM_004168.4(SDHA):c.1261-10C>T	6389	SDHA	Likely benign	1579409244	RCV002198179;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	236533	236533	236533	-
NM_004168.4(SDHA):c.1261-9T>A	6389	SDHA	Uncertain significance	1553999698	RCV000649452;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236534	236534	NC_000005.9:g.236534T>A	ClinGen:CA658796488	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1261-9T>C	6389	SDHA	Likely benign	1553999698	RCV001399597;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236534	236534	236534	-
NM_004168.4(SDHA):c.1261-7T>A	6389	SDHA	Likely benign	1423583851	RCV001047440;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	236536	236536	5:g.236536T>A	-
NM_004168.4(SDHA):c.1261-7T>G	6389	SDHA	Likely benign	1423583851	RCV001359103;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	236536	236536	236536	-
NM_004168.4(SDHA):c.1261-5C>A	6389	SDHA	Likely benign	751471707	RCV000649479;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236538	236538	NC_000005.9:g.236538C>A	ClinGen:CA3173177	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1261-4A>T	6389	SDHA	Likely benign	1553999703	RCV000544427;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	236539	236539	NC_000005.9:g.236539A>T	ClinGen:CA658657410	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1261-4A>G	6389	SDHA	Conflicting interpretations of pathogenicity	1553999703	RCV001481591\|RCV002439151;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	236539	236539	236539	-
NM_004168.4(SDHA):c.1261-3C>T	6389	SDHA	Conflicting interpretations of pathogenicity	1553999705	RCV000649473\|RCV002440351;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	236540	236540	5:g.236540C>T	ClinGen:CA658796490	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1261-2A>G	6389	SDHA	Likely pathogenic	1579409293	RCV000822495\|RCV003307557\|RCV003453730;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236541	236541	5:g.236541A>G	-
NM_004168.4(SDHA):c.1261-1G>A	6389	SDHA	Likely pathogenic	1735779936	RCV001205972;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236542	236542	5:g.236542G>A	-
NM_004168.4(SDHA):c.1263C>T (p.Val421=)	6389	SDHA	Likely benign	2126589252	RCV002131230\|RCV002443236;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	236545	236545	236545	-
NM_004168.4(SDHA):c.1264C>T (p.Leu422=)	6389	SDHA	Likely benign	1405485459	RCV002131104\|RCV002443235;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	236546	236546	236546	-
NM_004168.4(SDHA):c.1271A>G (p.His424Arg)	6389	SDHA	Uncertain significance	1579409312	RCV001010658\|RCV001860645;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236553	236553	5:g.236553A>G	-
NM_004168.4(SDHA):c.1272C>G (p.His424Gln)	6389	SDHA	Uncertain significance	754805626	RCV000477192\|RCV000521376\|RCV001010677;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	236554	236554	NC_000005.9:g.236554C>G	ClinGen:CA3173178	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1272C>T (p.His424=)	6389	SDHA	Likely benign	754805626	RCV000556683\|RCV000561553;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	236554	236554	5:g.236554C>T	ClinGen:CA3173179	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1273G>A (p.Val425Met)	6389	SDHA	Uncertain significance	201822097	RCV000231334\|RCV000569607\|RCV000663187\|RCV001753700\|RCV002503907\|RCV003475066;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|	5	236555	236555	5:g.236555G>A	ClinGen:CA3173181	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1273G>T (p.Val425Leu)	6389	SDHA	Uncertain significance	201822097	RCV000532863\|RCV000573766;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	236555	236555	NC_000005.9:g.236555G>T	ClinGen:CA3173180	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1276A>C (p.Asn426His)	6389	SDHA	Uncertain significance	1735781689	RCV001901493;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236558	236558	236558	-
NM_004168.4(SDHA):c.1277A>G (p.Asn426Ser)	6389	SDHA	Uncertain significance	1060503725	RCV000463371;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236559	236559	NC_000005.9:g.236559A>G	ClinGen:CA16611963	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1278T>C (p.Asn426=)	6389	SDHA	Likely benign	2126589395	RCV002089352;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	236560	236560	236560	-
NM_004168.4(SDHA):c.1280G>T (p.Gly427Val)	6389	SDHA	Uncertain significance	1735782215	RCV001203852;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236562	236562	5:g.236562G>T	-
NM_004168.4(SDHA):c.1283_1298del (p.Gln428fs)	6389	SDHA	Pathogenic	-1	RCV002289321\|RCV003097776\|RCV003340474\|RCV003475330;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|	5	236562	236577	236561	-
NM_004168.4(SDHA):c.1281C>T (p.Gly427=)	6389	SDHA	Likely benign	561918468	RCV000570135\|RCV000792107;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236563	236563	NC_000005.9:g.236563C>T	ClinGen:CA3173182	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1284G>C (p.Gln428His)	6389	SDHA	Uncertain significance	1735782951	RCV001961029;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	236566	236566	236566	-
NM_004168.4(SDHA):c.1285G>A (p.Asp429Asn)	6389	SDHA	Uncertain significance	988419580	RCV001866324\|RCV003289124;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	236567	236567	236567	-
NM_004168.4(SDHA):c.1287T>G (p.Asp429Glu)	6389	SDHA	Uncertain significance	-1	RCV002846176;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236569	236569	NC_000005.9:g.236569T>G	-
NM_004168.4(SDHA):c.1290G>A (p.Gln430=)	6389	SDHA	Likely benign	772728779	RCV000545202\|RCV002384220;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	236572	236572	5:g.236572G>A	ClinGen:CA442692072	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1291A>G (p.Ile431Val)	6389	SDHA	Conflicting interpretations of pathogenicity	1579409384	RCV000796031\|RCV003307439;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	236573	236573	5:g.236573A>G	-
NM_004168.4(SDHA):c.1292T>C (p.Ile431Thr)	6389	SDHA	Uncertain significance	776188923	RCV000461342\|RCV002383838;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	236574	236574	NC_000005.9:g.236574T>C	ClinGen:CA3173184	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1294G>A (p.Val432Met)	6389	SDHA	Uncertain significance	2126589526	RCV001362125;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236576	236576	236576	-
NM_004168.4(SDHA):c.1295T>C (p.Val432Ala)	6389	SDHA	Uncertain significance	1490844767	RCV001372668\|RCV002384540;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	236577	236577	236577	-
NM_004168.4(SDHA):c.1296G>T (p.Val432=)	6389	SDHA	Likely benign	1223308548	RCV002198178;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	236578	236578	236578	-
NM_004168.4(SDHA):c.1296G>A (p.Val432=)	6389	SDHA	Likely benign	-1	RCV003095824;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236578	236578		-
NM_004168.4(SDHA):c.1297C>T (p.Pro433Ser)	6389	SDHA	Uncertain significance	1560998056	RCV000687479;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236579	236579	5:g.236579C>T	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1298C>T (p.Pro433Leu)	6389	SDHA	Uncertain significance	747488969	RCV000649415\|RCV002386095;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	236580	236580	NC_000005.9:g.236580C>T	ClinGen:CA3173185	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1299C>T (p.Pro433=)	6389	SDHA	Likely benign	144473374	RCV000233072\|RCV000566607;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	236581	236581	NC_000005.9:g.236581C>T	ClinGen:CA3173186	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1300G>A (p.Gly434Ser)	6389	SDHA	Uncertain significance	529198317	RCV000557736\|RCV001010859\|RCV003327419;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	5	236582	236582	5:g.236582G>A	ClinGen:CA3173187	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1300G>C (p.Gly434Arg)	6389	SDHA	Uncertain significance	529198317	RCV001878075;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236582	236582	236582	-
NM_004168.4(SDHA):c.1302C>T (p.Gly434=)	6389	SDHA	Likely benign	1579409486	RCV001211773;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236584	236584	5:g.236584C>T	-
NM_004168.4(SDHA):c.1304T>A (p.Leu435Gln)	6389	SDHA	Uncertain significance	1579409500	RCV001010873\|RCV002549330;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236586	236586	5:g.236586T>A	-
NM_004168.4(SDHA):c.1304T>G (p.Leu435Arg)	6389	SDHA	Uncertain significance	1579409500	RCV001957990\|RCV002386771;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	236586	236586	236586	-
NM_004168.4(SDHA):c.1304T>C (p.Leu435Pro)	6389	SDHA	Uncertain significance	1579409500	RCV001895333;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	236586	236586	236586	-
NM_004168.4(SDHA):c.1305G>T (p.Leu435=)	6389	SDHA	Conflicting interpretations of pathogenicity	35964044	RCV000210529\|RCV000291485\|RCV000346462\|RCV000376037\|RCV000242588\|RCV000565630\|RCV003114371\|RCV003316166;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO	5	236587	236587	NC_000005.9:g.236587G>T	ClinGen:CA358583	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1305G>C (p.Leu435=)	6389	SDHA	Likely benign	35964044	RCV000533635\|RCV002384221;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	236587	236587	NC_000005.9:g.236587G>C	ClinGen:CA442692084	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1305G>A (p.Leu435=)	6389	SDHA	Likely benign	35964044	RCV001010877\|RCV001410811;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236587	236587	5:g.236587G>A	-
NM_004168.4(SDHA):c.1306T>C (p.Tyr436His)	6389	SDHA	Uncertain significance	772729820	RCV001206499\|RCV002379782;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	236588	236588	5:g.236588T>C	-
NM_004168.4(SDHA):c.1316_1330dup (p.Gly439_Cys443dup)	6389	SDHA	Uncertain significance	768469627	RCV000570645\|RCV001858148;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236589	236590	5:g.236589_236590insCGCCTGTGGGGAGGC	ClinGen:CA658657411	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1308C>T (p.Tyr436=)	6389	SDHA	Likely benign	762494024	RCV000550792\|RCV001010906\|RCV003316718;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236590	236590	NC_000005.9:g.236590C>T	ClinGen:CA3173191	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1309G>A (p.Ala437Thr)	6389	SDHA	Uncertain significance	1553999731	RCV000649418\|RCV002386096;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	236591	236591	5:g.236591G>A	ClinGen:CA359013896	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1311C>T (p.Ala437=)	6389	SDHA	Likely benign	377506772	RCV000563511\|RCV000649480;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236593	236593	5:g.236593C>T	ClinGen:CA3173192	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1313G>T (p.Cys438Phe)	6389	SDHA	Uncertain significance	1424809160	RCV000649397\|RCV002386094;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	236595	236595	5:g.236595G>T	ClinGen:CA359013907	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1313G>C (p.Cys438Ser)	6389	SDHA	Uncertain significance	1424809160	RCV001295683\|RCV002379989;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	236595	236595	236595	-
NM_004168.4(SDHA):c.1315G>A (p.Gly439Arg)	6389	SDHA	Uncertain significance	1579409601	RCV001201712;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236597	236597	5:g.236597G>A	-
NM_004168.4(SDHA):c.1316G>A (p.Gly439Glu)	6389	SDHA	Uncertain significance	374086655	RCV001224984\|RCV003380908;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	236598	236598	5:g.236598G>A	-
NM_004168.4(SDHA):c.1318G>A (p.Glu440Lys)	6389	SDHA	Uncertain significance	1735789566	RCV001956896\|RCV002386828;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	236600	236600	236600	-
NM_004168.4(SDHA):c.1319A>G (p.Glu440Gly)	6389	SDHA	Uncertain significance	1735789704	RCV001236035;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236601	236601	5:g.236601A>G	-
NM_004168.4(SDHA):c.1319A>T (p.Glu440Val)	6389	SDHA	Uncertain significance	1735789704	RCV001321130;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236601	236601	236601	-
NM_004168.4(SDHA):c.1319A>C (p.Glu440Ala)	6389	SDHA	Uncertain significance	-1	RCV002302872;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236601	236601	236601	-
NM_004168.4(SDHA):c.1320G>A (p.Glu440=)	6389	SDHA	Likely benign	2126589773	RCV001446278\|RCV002384689;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	236602	236602	236602	-
NM_004168.4(SDHA):c.1320G>C (p.Glu440Asp)	6389	SDHA	Uncertain significance	-1	RCV003043996;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236602	236602	NC_000005.9:g.236602G>C	-
NM_004168.4(SDHA):c.1321G>C (p.Ala441Pro)	6389	SDHA	Uncertain significance	-1	RCV002302051;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236603	236603	236603	-
NM_004168.4(SDHA):c.1323C>T (p.Ala441=)	6389	SDHA	Likely benign	751561561	RCV000574438\|RCV000878525\|RCV003316747;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236605	236605	NC_000005.9:g.236605C>T	ClinGen:CA3173193	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1323C>G (p.Ala441=)	6389	SDHA	Likely benign	751561561	RCV001464722;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236605	236605	236605	-
NM_004168.4(SDHA):c.1324G>A (p.Ala442Thr)	6389	SDHA	Uncertain significance	754893758	RCV000649436\|RCV001011018\|RCV002507115;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; M	5	236606	236606	NC_000005.9:g.236606G>A	ClinGen:CA3173194	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1324G>T (p.Ala442Ser)	6389	SDHA	Uncertain significance	754893758	RCV001971299;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236606	236606	236606	-
NM_004168.4(SDHA):c.1326C>T (p.Ala442=)	6389	SDHA	Likely benign	2126589832	RCV001438344\|RCV002384665;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	236608	236608	236608	-
NM_004168.4(SDHA):c.1327T>C (p.Cys443Arg)	6389	SDHA	Uncertain significance	2126589848	RCV001990756;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236609	236609	236609	-
NM_004168.4(SDHA):c.1329T>C (p.Cys443=)	6389	SDHA	Likely benign	2126589870	RCV001457888\|RCV002384720;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	236611	236611	236611	-
NM_004168.4(SDHA):c.1330_1331delinsTT (p.Ala444Phe)	6389	SDHA	Uncertain significance	1735790227	RCV001327910;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236612	236613	236612	-
NM_004168.4(SDHA):c.1332C>G (p.Ala444=)	6389	SDHA	Likely benign	1060505011	RCV000466826\|RCV001011097;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	236614	236614	NC_000005.9:g.236614C>G	ClinGen:CA16611968	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1334C>T (p.Ser445Leu)	6389	SDHA	Conflicting interpretations of pathogenicity	1296066077	RCV000559654\|RCV001011108\|RCV003237919\|RCV003476307;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642	5	236616	236616	5:g.236616C>T	ClinGen:CA359013953	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1335G>T (p.Ser445=)	6389	SDHA	Likely benign	200223188	RCV000465382\|RCV001010829\|RCV003437226;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	5	236617	236617	NC_000005.9:g.236617G>T	ClinGen:CA3173195	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1335G>A (p.Ser445=)	6389	SDHA	Likely benign	200223188	RCV000703828\|RCV001010827;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	236617	236617	5:g.236617G>A	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1336G>A (p.Val446Ile)	6389	SDHA	Uncertain significance	-1	RCV002705297;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236618	236618	NC_000005.9:g.236618G>A	-
NM_004168.4(SDHA):c.1338del (p.His447fs)	6389	SDHA	Pathogenic	1735791499	RCV001093471\|RCV001211082\|RCV003336306;	N	MedGen:C3661900\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236620	236620	5:g.236620_236620del	-
NM_004168.4(SDHA):c.1339C>T (p.His447Tyr)	6389	SDHA	Uncertain significance	2126589966	RCV001914544;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236621	236621	236621	-
NM_004168.4(SDHA):c.1340A>G (p.His447Arg)	6389	SDHA	Conflicting interpretations of pathogenicity	779151375	RCV000649422\|RCV000770776\|RCV001552485\|RCV003472043;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642	5	236622	236622	5:g.236622A>G	ClinGen:CA3173198	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1340A>C (p.His447Pro)	6389	SDHA	Uncertain significance	779151375	RCV001350157;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236622	236622	236622	-
NM_004168.4(SDHA):c.1341T>C (p.His447=)	6389	SDHA	Likely benign	2126589989	RCV001493357\|RCV002384814;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	236623	236623	236623	-
NM_004168.4(SDHA):c.1342G>A (p.Gly448Ser)	6389	SDHA	Uncertain significance	1064795863	RCV000483463\|RCV001851236;	N	MedGen:CN517202\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236624	236624	NC_000005.9:g.236624G>A	ClinGen:CA16618196
NM_004168.4(SDHA):c.1344T>C (p.Gly448=)	6389	SDHA	Benign/Likely benign	551497992	RCV000467921\|RCV000571567;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	236626	236626	NC_000005.9:g.236626T>C	ClinGen:CA3173200	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1345G>A (p.Ala449Thr)	6389	SDHA	Uncertain significance	1485193902	RCV001344676;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236627	236627	236627	-
NM_004168.4(SDHA):c.1345G>C (p.Ala449Pro)	6389	SDHA	Uncertain significance	-1	RCV002387815\|RCV003095007;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	236627	236627	236627	-
NM_004168.4(SDHA):c.1346C>G (p.Ala449Gly)	6389	SDHA	Uncertain significance	201139275	RCV000575726\|RCV000535887;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	236628	236628	5:g.236628C>G	ClinGen:CA359013974	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1349A>G (p.Asn450Ser)	6389	SDHA	Uncertain significance	1579409723	RCV000819929\|RCV002381857\|RCV003473505;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	236631	236631	5:g.236631A>G	-
NM_004168.4(SDHA):c.1350C>T (p.Asn450=)	6389	SDHA	Likely benign	533902090	RCV000565044\|RCV000649477;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236632	236632	NC_000005.9:g.236632C>T	ClinGen:CA3173202	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1351C>T (p.Arg451Cys)	6389	SDHA	Conflicting interpretations of pathogenicity	1553999752	RCV000521022\|RCV001063769\|RCV001363197\|RCV001799673\|RCV002384004\|RCV003152716;	N	MedGen:C3661900\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0031006,MedGen:C5543254,OMIM:619259\|Human Phenotype Ontology:HP:0100723,MONDO:MONDO:0011719,MeSH:D04	5	236633	236633	NC_000005.9:g.236633C>T	ClinGen:CA359013985,OMIM:600857.0011
NM_004168.4(SDHA):c.1351C>A (p.Arg451Ser)	6389	SDHA	Conflicting interpretations of pathogenicity	1553999752	RCV001265565\|RCV001244671\|RCV002379936;	N	\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	236633	236633	5:g.236633C>A	-
NM_004168.4(SDHA):c.1352G>A (p.Arg451His)	6389	SDHA	Conflicting interpretations of pathogenicity	370690436	RCV000705227\|RCV001594402\|RCV002256488\|RCV002536395;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|Me	5	236634	236634	5:g.236634G>A	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1353C>G (p.Arg451=)	6389	SDHA	Likely benign	555342133	RCV000566165\|RCV000649481;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236635	236635	5:g.236635C>G	ClinGen:CA3173204	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1354C>T (p.Leu452Phe)	6389	SDHA	Uncertain significance	1064796477	RCV000479013\|RCV000569661\|RCV000793091;	N	MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236636	236636	NC_000005.9:g.236636C>T	ClinGen:CA16618197
NM_004168.4(SDHA):c.1355T>C (p.Leu452Pro)	6389	SDHA	Uncertain significance	1735794275	RCV001321882;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236637	236637	236637	-
NM_004168.4(SDHA):c.1356C>T (p.Leu452=)	6389	SDHA	Likely benign	748496836	RCV000420514\|RCV000464405\|RCV000567112;	N	MedGen:CN169374\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	236638	236638	5:g.236638C>T	ClinGen:CA3173205	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1357G>A (p.Gly453Arg)	6389	SDHA	Uncertain significance	770028533	RCV000548237\|RCV001011154\|RCV003476308;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	236639	236639	NC_000005.9:g.236639G>A	ClinGen:CA3173206	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1358G>A (p.Gly453Glu)	6389	SDHA	Uncertain significance	1169286790	RCV000793933;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236640	236640	5:g.236640G>A	-
NM_004168.4(SDHA):c.1360G>T (p.Ala454Ser)	6389	SDHA	Uncertain significance	1057517550	RCV000704760;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236642	236642	NC_000005.9:g.236642G>T	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1361C>A (p.Ala454Glu)	6389	SDHA	Uncertain significance	1553999766	RCV000528914\|RCV002384222;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	236643	236643	NC_000005.9:g.236643C>A	ClinGen:CA359014000	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1365C>T (p.Asn455=)	6389	SDHA	Likely benign	1579409853	RCV001011058\|RCV002068835;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236647	236647	5:g.236647C>T	-
NM_004168.4(SDHA):c.1366T>G (p.Ser456Ala)	6389	SDHA	Uncertain significance	-1	RCV002671393;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236648	236648	NC_000005.9:g.236648T>G	-
NM_004168.4(SDHA):c.1367C>T (p.Ser456Leu)	6389	SDHA	Conflicting interpretations of pathogenicity	76896145	RCV000649467\|RCV001354634\|RCV002386098;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	236649	236649	5:g.236649C>T	ClinGen:CA3173208	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1368G>A (p.Ser456=)	6389	SDHA	Conflicting interpretations of pathogenicity	149875171	RCV000210523\|RCV000247565\|RCV000570838\|RCV001080809\|RCV001157831\|RCV001157832\|RCV001157833\|RCV003316163;	N	MedGen:C3661900\|MedGen:CN169374\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0009723,MedGen:C002	5	236650	236650	NC_000005.9:g.236650G>A	ClinGen:CA358579	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1370T>A (p.Leu457His)	6389	SDHA	Uncertain significance	1579409887	RCV001011188\|RCV002298821\|RCV003473566;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	236652	236652	5:g.236652T>A	-
NM_004168.4(SDHA):c.1371C>A (p.Leu457=)	6389	SDHA	Benign/Likely benign	75091805	RCV001512875\|RCV002258297;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	236653	236653	236653	-
NM_004168.4(SDHA):c.1371C>G (p.Leu457=)	6389	SDHA	Likely benign	75091805	RCV002142112;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	236653	236653	236653	-
NM_004168.4(SDHA):c.1374G>A (p.Leu458=)	6389	SDHA	Uncertain significance	1735797053	RCV001060517;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236656	236656	5:g.236656G>A	-
NM_004168.4(SDHA):c.1375G>C (p.Asp459His)	6389	SDHA	Uncertain significance	1735797208	RCV001042958\|RCV002256652;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	236657	236657	5:g.236657G>C	-
NM_004168.4(SDHA):c.1376A>G (p.Asp459Gly)	6389	SDHA	Uncertain significance	2126590273	RCV001364342;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236658	236658	236658	-
NM_004168.4(SDHA):c.1377C>T (p.Asp459=)	6389	SDHA	Likely benign	1579409909	RCV000924630\|RCV003307696;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	236659	236659	5:g.236659C>T	-
NM_004168.4(SDHA):c.1378C>T (p.Leu460=)	6389	SDHA	Likely benign	760686493	RCV000541221\|RCV000573583\|RCV002476187;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	5	236660	236660	NC_000005.9:g.236660C>T	ClinGen:CA3173210	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1380G>A (p.Leu460=)	6389	SDHA	Likely benign	-1	RCV003046708;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236662	236662		-
NM_004168.4(SDHA):c.1381G>T (p.Val461Phe)	6389	SDHA	Uncertain significance	373021394	RCV001011289\|RCV001223002;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236663	236663	5:g.236663G>T	-
NM_004168.4(SDHA):c.1382T>C (p.Val461Ala)	6389	SDHA	Uncertain significance	767452676	RCV000649421\|RCV002386097;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	236664	236664	5:g.236664T>C	ClinGen:CA3173211	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1387T>C (p.Phe463Leu)	6389	SDHA	Uncertain significance	-1	RCV002843615;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236669	236669	NC_000005.9:g.236669T>C	-
NM_004168.4(SDHA):c.1389T>C (p.Phe463=)	6389	SDHA	Likely benign	2126590369	RCV001395196;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236671	236671	236671	-
NM_004168.4(SDHA):c.1390G>A (p.Gly464Ser)	6389	SDHA	Uncertain significance	2126590387	RCV001993894;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	236672	236672	236672	-
NM_004168.4(SDHA):c.1390G>C (p.Gly464Arg)	6389	SDHA	Uncertain significance	-1	RCV002838852;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236672	236672	NC_000005.9:g.236672G>C	-
NM_004168.4(SDHA):c.1392T>G (p.Gly464=)	6389	SDHA	Likely benign	1579409940	RCV001417559;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236674	236674	5:g.236674T>G	-
NM_004168.4(SDHA):c.1393C>T (p.Arg465Trp)	6389	SDHA	Uncertain significance	752461029	RCV000227745\|RCV001011310\|RCV003475067;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	236675	236675	NC_000005.9:g.236675C>T	ClinGen:CA3173212	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1393C>A (p.Arg465=)	6389	SDHA	Likely benign	752461029	RCV001220483;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236675	236675	5:g.236675C>A	-
NM_004168.4(SDHA):c.1394G>A (p.Arg465Gln)	6389	SDHA	Conflicting interpretations of pathogenicity	138277996	RCV000865554\|RCV001011316\|RCV001547986;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	5	236676	236676	5:g.236676G>A	-
NM_004168.4(SDHA):c.1396G>T (p.Ala466Ser)	6389	SDHA	Uncertain significance	111387770	RCV000525154;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	236678	236678	5:g.236678G>T	ClinGen:CA359014067	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1396G>A (p.Ala466Thr)	6389	SDHA	Conflicting interpretations of pathogenicity	111387770	RCV000549321\|RCV000574670\|RCV001528282\|RCV001572933;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN169374\|MedGen:C3661900	5	236678	236678	NC_000005.9:g.236678G>A	ClinGen:CA3173214	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1397dup (p.Cys467fs)	6389	SDHA	Pathogenic	1735798915	RCV001061275;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236678	236679	5:g.236678_236679insC	-
NM_004168.4(SDHA):c.1396G>C (p.Ala466Pro)	6389	SDHA	Uncertain significance	-1	RCV002295188;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236678	236678	236678	-
NM_004168.4(SDHA):c.1398A>G (p.Ala466=)	6389	SDHA	Likely benign	878854626	RCV001458162\|RCV002392697;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	236680	236680	5:g.236680A>G	ClinGen:CA10582428	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1398A>C (p.Ala466=)	6389	SDHA	Likely benign	878854626	RCV001465001;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236680	236680	5:g.236680A>C	-
NM_004168.4(SDHA):c.1403C>T (p.Ala468Val)	6389	SDHA	Uncertain significance	1057524636	RCV001364058;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236685	236685	236685	-
NM_004168.4(SDHA):c.1408A>C (p.Ser470Arg)	6389	SDHA	Uncertain significance	1735799664	RCV001295152;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	236690	236690	236690	-
NM_004168.4(SDHA):c.1409G>A (p.Ser470Asn)	6389	SDHA	Uncertain significance	1241820374	RCV000812060\|RCV001011430;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	236691	236691	5:g.236691G>A	-
NM_004168.4(SDHA):c.1409G>T (p.Ser470Ile)	6389	SDHA	Uncertain significance	-1	RCV002296840;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236691	236691	236691	-
NM_004168.4(SDHA):c.1410C>T (p.Ser470=)	6389	SDHA	Likely benign	556476038	RCV000542300\|RCV001011405\|RCV003316719;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236692	236692	5:g.236692C>T	ClinGen:CA3173215	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1411A>G (p.Ile471Val)	6389	SDHA	Uncertain significance	1735800203	RCV001230166;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236693	236693	5:g.236693A>G	-
NM_004168.4(SDHA):c.1413C>T (p.Ile471=)	6389	SDHA	Conflicting interpretations of pathogenicity	34779890	RCV000210520\|RCV000437200\|RCV000562445\|RCV001157834\|RCV001152356\|RCV001152357\|RCV001579483\|RCV003316168;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MedGen:CN169374\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011	5	236695	236695	NC_000005.9:g.236695C>T	ClinGen:CA358577	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1413C>G (p.Ile471Met)	6389	SDHA	Uncertain significance	34779890	RCV001039572;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	236695	236695	5:g.236695C>G	-
NM_004168.4(SDHA):c.1414G>A (p.Glu472Lys)	6389	SDHA	Conflicting interpretations of pathogenicity	143798161	RCV000409873\|RCV000569994\|RCV000806481;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236696	236696	NC_000005.9:g.236696G>A	ClinGen:CA3173216	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1414G>T (p.Glu472Ter)	6389	SDHA	Pathogenic	-1	RCV002391669\|RCV003095123;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236696	236696	236696	-
NM_004168.4(SDHA):c.1417G>C (p.Glu473Gln)	6389	SDHA	Uncertain significance	2126590644	RCV001900975;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	236699	236699	236699	-
NM_004168.4(SDHA):c.1418A>C (p.Glu473Ala)	6389	SDHA	Uncertain significance	1560998495	RCV000698751\|RCV003352990;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	236700	236700	5:g.236700A>C	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1419G>A (p.Glu473=)	6389	SDHA	Likely benign	898003329	RCV000465651\|RCV000575876;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	236701	236701	NC_000005.9:g.236701G>A	ClinGen:CA16611971	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1420T>C (p.Ser474Pro)	6389	SDHA	Uncertain significance	2126590674	RCV001978486;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236702	236702	236702	-
NM_004168.4(SDHA):c.1422A>G (p.Ser474=)	6389	SDHA	Likely benign	201868424	RCV000553507;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	236704	236704	NC_000005.9:g.236704A>G	ClinGen:CA3173218	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1423T>C (p.Cys475Arg)	6389	SDHA	Uncertain significance	781747137	RCV000234575\|RCV000663132\|RCV002392698\|RCV003475068;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|	5	236705	236705	5:g.236705T>C	ClinGen:CA3173219	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1424G>C (p.Cys475Ser)	6389	SDHA	Uncertain significance	748567636	RCV000649405\|RCV003303064\|RCV003432690;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	5	236706	236706	5:g.236706G>C	ClinGen:CA3173221	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1424G>A (p.Cys475Tyr)	6389	SDHA	Uncertain significance	748567636	RCV001011482\|RCV001235217;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236706	236706	5:g.236706G>A	-
NM_004168.4(SDHA):c.1427G>A (p.Arg476Lys)	6389	SDHA	Uncertain significance	2126590736	RCV001932270;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236709	236709	236709	-
NM_004168.4(SDHA):c.1428G>A (p.Arg476=)	6389	SDHA	Likely benign	377415114	RCV000529616\|RCV001011491;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	236710	236710	NC_000005.9:g.236710G>A	ClinGen:CA3173222	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1428G>T (p.Arg476Ser)	6389	SDHA	Uncertain significance	377415114	RCV000541924\|RCV002395443\|RCV003319375;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	5	236710	236710	5:g.236710G>T	ClinGen:CA3173223	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1428G>C (p.Arg476Ser)	6389	SDHA	Uncertain significance	377415114	RCV001070472\|RCV002393339;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	236710	236710	5:g.236710G>C	-
NM_004168.4(SDHA):c.1429C>T (p.Pro477Ser)	6389	SDHA	Uncertain significance	770506764	RCV000468284\|RCV001011494\|RCV002481479\|RCV003237875;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; M	5	236711	236711	NC_000005.9:g.236711C>T	ClinGen:CA3173224	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1430C>A (p.Pro477His)	6389	SDHA	Uncertain significance	146990772	RCV000649419;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236712	236712	5:g.236712C>A	ClinGen:CA359014138	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1430C>T (p.Pro477Leu)	6389	SDHA	Uncertain significance	146990772	RCV000696212\|RCV000998346\|RCV002388266;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	236712	236712	5:g.236712C>T	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1432_1432+1del	6389	SDHA	Pathogenic/Likely pathogenic	878854627	RCV000228421\|RCV000567345\|RCV001253762\|RCV002508205\|RCV002500781\|RCV003475069;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|Human Phenotype Ontology:HP:0002668,Human Phenotype Ontology:HP	5	236714	236715	5:g.236714_236715del	ClinGen:CA10582429	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1432+1G>C	6389	SDHA	Likely pathogenic	878854628	RCV000230417\|RCV001329182;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	236715	236715	5:g.236715G>C	ClinGen:CA10582430	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1432+1G>T	6389	SDHA	Likely pathogenic	878854628	RCV002037154;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236715	236715	236715	-
NM_004168.4(SDHA):c.1432+4A>G	6389	SDHA	Uncertain significance	1553999798	RCV000649399\|RCV002388130;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	236718	236718	5:g.236718A>G	ClinGen:CA658796491	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1432+7G>C	6389	SDHA	Likely benign	760526397	RCV000234401\|RCV000662744\|RCV001800594;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MedGen:CN517202	5	236721	236721	NC_000005.9:g.236721G>C	ClinGen:CA3173229	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1432+7G>T	6389	SDHA	Likely benign	760526397	RCV001475830;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236721	236721	236721	-
NM_004168.4(SDHA):c.1432+7G>A	6389	SDHA	Likely benign	760526397	RCV002135293;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236721	236721	236721	-
NM_004168.4(SDHA):c.1432+9_1432+11del	6389	SDHA	Likely benign	2126590852	RCV002116679;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	236722	236724	236721	-
NM_004168.4(SDHA):c.1432+9T>G	6389	SDHA	Likely benign	1735803426	RCV002082719;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	236723	236723	236723	-
NM_004168.4(SDHA):c.1432+10T>C	6389	SDHA	Likely benign	-1	RCV002863823;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236724	236724	NC_000005.9:g.236724T>C	-
NM_004168.4(SDHA):c.1432+12C>T	6389	SDHA	Likely benign	377104463	RCV002165760;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236726	236726	236726	-
NM_004168.4(SDHA):c.1432+15C>T	6389	SDHA	Likely benign	2126590874	RCV002201621;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	236729	236729	236729	-
NM_004168.4(SDHA):c.1432+16A>G	6389	SDHA	Conflicting interpretations of pathogenicity	753631065	RCV000409517\|RCV002058840;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	236730	236730	5:g.236730A>G	ClinGen:CA3173231	C3279992 614165 Paragangliomas 5;
NM_004168.4(SDHA):c.1432+18G>C	6389	SDHA	Likely benign	763298397	RCV002170141;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236732	236732	236732	-
NM_004168.4(SDHA):c.1432+20G>C	6389	SDHA	Benign/Likely benign	200127852	RCV000663191\|RCV002060801;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	236734	236734	5:g.236734G>C	-	C3279992 614165 Paragangliomas 5;
NM_004168.4(SDHA):c.1433-19T>C	6389	SDHA	Likely benign	2126602340	RCV002213576;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	240454	240454	240454	-
NM_004168.4(SDHA):c.1433-18A>G	6389	SDHA	Likely benign	-1	RCV002904201;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240455	240455	NC_000005.9:g.240455A>G	-
NM_004168.4(SDHA):c.1433-8dup	6389	SDHA	Benign	769594966	RCV002136909;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	240457	240458	240457	-
NM_004168.4(SDHA):c.1433-16C>G	6389	SDHA	Likely benign	-1	RCV002894775;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240457	240457	NC_000005.9:g.240457C>G	-
NM_004168.4(SDHA):c.1433-8del	6389	SDHA	Benign	-1	RCV003082251;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240458	240458	NC_000005.9:g.240465del	-
NM_004168.4(SDHA):c.1433-15T>A	6389	SDHA	Likely benign	-1	RCV003054675;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240458	240458	NC_000005.9:g.240458T>A	-
NM_004168.4(SDHA):c.1433-14T>C	6389	SDHA	Likely benign	2126602367	RCV002185104;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240459	240459	240459	-
NM_004168.4(SDHA):c.1433-14T>G	6389	SDHA	Likely benign	2126602367	RCV002175598;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	240459	240459	240459	-
NM_004168.4(SDHA):c.1433-14T>A	6389	SDHA	Likely benign	2126602367	RCV002145985;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240459	240459	240459	-
NM_004168.4(SDHA):c.1433-11T>G	6389	SDHA	Likely benign	1194122879	RCV002172332;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240462	240462	240462	-
NM_004168.4(SDHA):c.1433-10T>C	6389	SDHA	Likely benign	1214392431	RCV000945795;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	240463	240463	5:g.240463T>C	-
NM_004168.4(SDHA):c.1433-9T>C	6389	SDHA	Likely benign	1579417426	RCV001419853;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240464	240464	5:g.240464T>C	-
NM_004168.4(SDHA):c.1433-8T>G	6389	SDHA	Likely benign	2126602401	RCV002207740;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240465	240465	240465	-
NM_004168.4(SDHA):c.1433-7G>A	6389	SDHA	Likely benign	-1	RCV003080398;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240466	240466	NC_000005.9:g.240466G>A	-
NM_004168.4(SDHA):c.1433-3del	6389	SDHA	Benign	2126602411	RCV001518617;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240467	240467	240466	-
NM_004168.4(SDHA):c.1433-5T>A	6389	SDHA	Likely benign	2126602416	RCV002004228;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240468	240468	240468	-
NM_004168.4(SDHA):c.1433-4T>G	6389	SDHA	Likely benign	2126602419	RCV001418129;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240469	240469	240469	-
NM_004168.4(SDHA):c.1433-3T>C	6389	SDHA	Uncertain significance	1736060812	RCV001208443;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240470	240470	5:g.240470T>C	-
NM_004168.4(SDHA):c.1433-2A>G	6389	SDHA	Likely pathogenic	-1	RCV002851247;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240471	240471	NC_000005.9:g.240471A>G	-
NM_004168.4(SDHA):c.1437_1438insGT (p.Lys480fs)	6389	SDHA	Pathogenic	-1	RCV003035160;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240476	240477	NC_000005.9:g.240477_240478insGT	-
NM_004168.4(SDHA):c.1438A>G (p.Lys480Glu)	6389	SDHA	Uncertain significance	1579417444	RCV001011574\|RCV001247825;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240478	240478	5:g.240478A>G	-
NM_004168.4(SDHA):c.1442T>G (p.Val481Gly)	6389	SDHA	Uncertain significance	1736061170	RCV001959617;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	240482	240482	240482	-
NM_004168.4(SDHA):c.1443C>A (p.Val481=)	6389	SDHA	Likely benign	751871185	RCV000649466\|RCV003303066;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	240483	240483	5:g.240483C>A	ClinGen:CA442692193	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1443C>T (p.Val481=)	6389	SDHA	Likely benign	751871185	RCV002182582;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240483	240483	240483	-
NM_004168.4(SDHA):c.1445C>T (p.Pro482Leu)	6389	SDHA	Uncertain significance	759661610	RCV001011619\|RCV001860674;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240485	240485	5:g.240485C>T	-
NM_004168.4(SDHA):c.1445C>A (p.Pro482His)	6389	SDHA	Uncertain significance	759661610	RCV001220887;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240485	240485	5:g.240485C>A	-
NM_004168.4(SDHA):c.1445C>G (p.Pro482Arg)	6389	SDHA	Uncertain significance	759661610	RCV002010926;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240485	240485	240485	-
NM_004168.4(SDHA):c.1446T>G (p.Pro482=)	6389	SDHA	Likely benign	767646499	RCV001493756\|RCV002388523;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	240486	240486	240486	-
NM_004168.4(SDHA):c.1448C>T (p.Pro483Leu)	6389	SDHA	Uncertain significance	2126602519	RCV001890957;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240488	240488	240488	-
NM_004168.4(SDHA):c.1450A>G (p.Ile484Val)	6389	SDHA	Uncertain significance	1224049828	RCV000554522\|RCV002395444;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	240490	240490	NC_000005.9:g.240490A>G	ClinGen:CA359014191	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1452T>C (p.Ile484=)	6389	SDHA	Likely benign	-1	RCV002394648\|RCV003095185;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240492	240492		-
NM_004168.4(SDHA):c.1453A>G (p.Lys485Glu)	6389	SDHA	Uncertain significance	1736062209	RCV001347124\|RCV002395765;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	240493	240493	240493	-
NM_004168.4(SDHA):c.1453A>C (p.Lys485Gln)	6389	SDHA	Uncertain significance	-1	RCV002647631;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240493	240493	NC_000005.9:g.240493A>C	-
NM_004168.4(SDHA):c.1456C>A (p.Pro486Thr)	6389	SDHA	Conflicting interpretations of pathogenicity	1060503706	RCV000462164\|RCV002256273;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	240496	240496	NC_000005.9:g.240496C>A	ClinGen:CA16611887	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1456C>T (p.Pro486Ser)	6389	SDHA	Uncertain significance	1060503706	RCV000530424;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	240496	240496	5:g.240496C>T	ClinGen:CA359014205	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1457C>T (p.Pro486Leu)	6389	SDHA	Uncertain significance	1579417528	RCV001011674\|RCV001860678;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240497	240497	5:g.240497C>T	-
NM_004168.4(SDHA):c.1458A>G (p.Pro486=)	6389	SDHA	Likely benign	2126602561	RCV001498115;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240498	240498	240498	-
NM_004168.4(SDHA):c.1459A>C (p.Asn487His)	6389	SDHA	Uncertain significance	1208182306	RCV001983493\|RCV002388998;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	240499	240499	240499	-
NM_004168.4(SDHA):c.1461C>T (p.Asn487=)	6389	SDHA	Likely benign	187540602	RCV000462565\|RCV000568309\|RCV003431042;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	5	240501	240501	NC_000005.9:g.240501C>T	ClinGen:CA3173258	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1461C>A (p.Asn487Lys)	6389	SDHA	Uncertain significance	-1	RCV002624452;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240501	240501	NC_000005.9:g.240501C>A	-
NM_004168.4(SDHA):c.1462G>A (p.Ala488Thr)	6389	SDHA	Uncertain significance	369100772	RCV000468600\|RCV000562914\|RCV000714731\|RCV000714730\|RCV002481484\|RCV003476133;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|M	5	240502	240502	NC_000005.9:g.240502G>A	ClinGen:CA3173259	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1462G>T (p.Ala488Ser)	6389	SDHA	Uncertain significance	369100772	RCV001205294\|RCV002393462;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	240502	240502	5:g.240502G>T	-
NM_004168.4(SDHA):c.1463C>T (p.Ala488Val)	6389	SDHA	Uncertain significance	1421325038	RCV001059668;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240503	240503	5:g.240503C>T	-
NM_004168.4(SDHA):c.1465G>A (p.Gly489Arg)	6389	SDHA	Uncertain significance	2126602614	RCV001899234;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	240505	240505	240505	-
NM_004168.4(SDHA):c.1466_1468del (p.Gly489del)	6389	SDHA	Uncertain significance	-1	RCV003046834;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240505	240507	NC_000005.9:g.240506_240508del	-
NM_004168.4(SDHA):c.1468G>T (p.Glu490Ter)	6389	SDHA	Pathogenic/Likely pathogenic	1554000360	RCV000538564\|RCV001523818\|RCV002256388\|RCV003317276\|RCV003476302;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|	5	240508	240508	5:g.240508G>T	ClinGen:CA359014231	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1470_1473dup (p.Ser492fs)	6389	SDHA	Pathogenic	2126602655	RCV001969975;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240508	240509	240508	-
NM_004168.4(SDHA):c.1471G>T (p.Glu491Ter)	6389	SDHA	Conflicting interpretations of pathogenicity	778207102	RCV000555437\|RCV000566587\|RCV000779471\|RCV001093472\|RCV003409811\|RCV003476303;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|\|MedGen:C3661900\|\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:6136	5	240511	240511	NC_000005.9:g.240511G>T	ClinGen:CA3173260	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1471G>A (p.Glu491Lys)	6389	SDHA	Uncertain significance	778207102	RCV001224646;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240511	240511	5:g.240511G>A	-
NM_004168.4(SDHA):c.1472A>C (p.Glu491Ala)	6389	SDHA	Uncertain significance	754324916	RCV000649404\|RCV002388131;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	240512	240512	5:g.240512A>C	ClinGen:CA3173261	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1472A>G (p.Glu491Gly)	6389	SDHA	Uncertain significance	754324916	RCV000793864\|RCV001011765;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	240512	240512	5:g.240512A>G	-
NM_004168.4(SDHA):c.1476T>C (p.Ser492=)	6389	SDHA	Likely benign	1376968004	RCV000543040\|RCV002395445;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	240516	240516	5:g.240516T>C	ClinGen:CA442692215	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1477G>T (p.Val493Phe)	6389	SDHA	Uncertain significance	1579417619	RCV000801188;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240517	240517	5:g.240517G>T	-
NM_004168.4(SDHA):c.1479C>T (p.Val493=)	6389	SDHA	Likely benign	2126602710	RCV002155982\|RCV002391333;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	240519	240519	240519	-
NM_004168.4(SDHA):c.1480A>G (p.Met494Val)	6389	SDHA	Uncertain significance	1579417628	RCV000797162;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240520	240520	5:g.240520A>G	-
NM_004168.4(SDHA):c.1481T>C (p.Met494Thr)	6389	SDHA	Uncertain significance	1561001630	RCV000686308\|RCV003338732;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	240521	240521	NC_000005.9:g.240521T>C	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1483A>G (p.Asn495Asp)	6389	SDHA	Uncertain significance	757663708	RCV001945858\|RCV002491952;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154; MOND	5	240523	240523	240523	-
NM_004168.4(SDHA):c.1484A>T (p.Asn495Ile)	6389	SDHA	Uncertain significance	-1	RCV003022957;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240524	240524	NC_000005.9:g.240524A>T	-
NM_004168.4(SDHA):c.1486C>A (p.Leu496Ile)	6389	SDHA	Uncertain significance	1305001616	RCV001350259;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240526	240526	240526	-
NM_004168.4(SDHA):c.1491C>G (p.Asp497Glu)	6389	SDHA	Uncertain significance	1579417658	RCV000796925\|RCV002388445;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	240531	240531	5:g.240531C>G	-
NM_004168.4(SDHA):c.1492A>C (p.Lys498Gln)	6389	SDHA	Uncertain significance	-1	RCV002389721\|RCV003095233;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240532	240532	240532	-
NM_004168.4(SDHA):c.1493A>G (p.Lys498Arg)	6389	SDHA	Uncertain significance	745592653	RCV000649413;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240533	240533	5:g.240533A>G	ClinGen:CA3173264	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1494_1516del (p.Lys498fs)	6389	SDHA	Pathogenic	-1	RCV002389756\|RCV003095236;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240533	240555	240532	-
NM_004168.4(SDHA):c.1493A>C (p.Lys498Thr)	6389	SDHA	Uncertain significance	-1	RCV003051544;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240533	240533	NC_000005.9:g.240533A>C	-
NM_004168.4(SDHA):c.1498A>C (p.Arg500=)	6389	SDHA	Likely benign	2126602800	RCV001462997\|RCV003160878;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	240538	240538	240538	-
NM_004168.4(SDHA):c.1500A>G (p.Arg500=)	6389	SDHA	Likely benign	-1	RCV002389921\|RCV003095249;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240540	240540		-
NM_004168.4(SDHA):c.1502T>G (p.Phe501Cys)	6389	SDHA	Uncertain significance	757932443	RCV000703345\|RCV002388325;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	240542	240542	5:g.240542T>G	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1506T>C (p.Ala502=)	6389	SDHA	Likely benign	1364448678	RCV001505748\|RCV002388562;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	240546	240546	240546	-
NM_004168.4(SDHA):c.1507G>A (p.Asp503Asn)	6389	SDHA	Uncertain significance	2126602837	RCV002012421\|RCV003382786;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	240547	240547	240547	-
NM_004168.4(SDHA):c.1508A>C (p.Asp503Ala)	6389	SDHA	Uncertain significance	1736066055	RCV001347501\|RCV002395768;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	240548	240548	240548	-
NM_004168.4(SDHA):c.1509T>C (p.Asp503=)	6389	SDHA	Likely benign	2126602858	RCV002134949;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	240549	240549	240549	-
NM_004168.4(SDHA):c.1510G>A (p.Gly504Arg)	6389	SDHA	Uncertain significance	1579417710	RCV000797915\|RCV003338804;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	240550	240550	5:g.240550G>A	-
NM_004168.4(SDHA):c.1514G>A (p.Ser505Asn)	6389	SDHA	Uncertain significance	1060503722	RCV000465966\|RCV002393171;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	240554	240554	NC_000005.9:g.240554G>A	ClinGen:CA16611974	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1516A>G (p.Ile506Val)	6389	SDHA	Uncertain significance	1561001683	RCV000821609;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240556	240556	5:g.240556A>G	-
NM_004168.4(SDHA):c.1517T>C (p.Ile506Thr)	6389	SDHA	Uncertain significance	2126602878	RCV001897289;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	240557	240557	240557	-
NM_004168.4(SDHA):c.1518A>G (p.Ile506Met)	6389	SDHA	Uncertain significance	955444699	RCV000691931\|RCV002388235;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	240558	240558	NC_000005.9:g.240558A>G	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1520G>A (p.Arg507Lys)	6389	SDHA	Uncertain significance	-1	RCV002300012;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240560	240560	240560	-
NM_004168.4(SDHA):c.1522A>T (p.Thr508Ser)	6389	SDHA	Uncertain significance	1060503718	RCV000475110\|RCV002393170;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	240562	240562	NC_000005.9:g.240562A>T	ClinGen:CA16611842	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1522A>G (p.Thr508Ala)	6389	SDHA	Uncertain significance	1060503718	RCV000649454;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240562	240562	5:g.240562A>G	ClinGen:CA359014353	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1523C>T (p.Thr508Ile)	6389	SDHA	Conflicting interpretations of pathogenicity	151266052	RCV000032785\|RCV000232220\|RCV000563852\|RCV001719715\|RCV001818204;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|M	5	240563	240563	5:g.240563C>T	ClinGen:CA130381,OMIM:600857.0006	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1524A>G (p.Thr508=)	6389	SDHA	Likely benign	1356814435	RCV000544975\|RCV002395446;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	240564	240564	5:g.240564A>G	ClinGen:CA442692244	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1525T>C (p.Ser509Pro)	6389	SDHA	Uncertain significance	1579417769	RCV000815995;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240565	240565	5:g.240565T>C	-
NM_004168.4(SDHA):c.1526C>T (p.Ser509Leu)	6389	SDHA	Uncertain significance	397514541	RCV000032786\|RCV000695865;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	240566	240566	5:g.240566C>T	ClinGen:CA130383,OMIM:600857.0007	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1526_1527delinsGA (p.Ser509Ter)	6389	SDHA	Pathogenic/Likely pathogenic	1064793567	RCV000483714\|RCV000575106\|RCV000800769\|RCV003401517\|RCV003476157;	N	MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:61364	5	240566	240567	NC_000005.9:g.240566_240567delinsGA	ClinGen:CA16618198
NM_004168.4(SDHA):c.1526C>G (p.Ser509Trp)	6389	SDHA	Conflicting interpretations of pathogenicity	397514541	RCV000998347\|RCV001053500\|RCV002391064;	N	MedGen:C3661900\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	240566	240566	5:g.240566C>G	-
NM_004168.4(SDHA):c.1527G>A (p.Ser509=)	6389	SDHA	Conflicting interpretations of pathogenicity	746453879	RCV000473824\|RCV000573305\|RCV001152360\|RCV001152358\|RCV001152359;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0017366,MedGen:C1708353, Orphanet:29072\|MONDO:MONDO:	5	240567	240567	NC_000005.9:g.240567G>A	ClinGen:CA3173266	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1531C>G (p.Leu511Val)	6389	SDHA	Uncertain significance	768257880	RCV001204913\|RCV002402589;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	240571	240571	5:g.240571C>G	-
NM_004168.4(SDHA):c.1531C>T (p.Leu511=)	6389	SDHA	Likely benign	768257880	RCV002109158\|RCV003161582;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	240571	240571	240571	-
NM_004168.4(SDHA):c.1532T>C (p.Leu511Pro)	6389	SDHA	Uncertain significance	375194444	RCV000225792\|RCV000484270\|RCV000571145\|RCV003417817\|RCV003475070;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:61364	5	240572	240572	NC_000005.9:g.240572T>C	ClinGen:CA3173268	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1533G>A (p.Leu511=)	6389	SDHA	Likely benign	876658698	RCV000218407\|RCV001411405;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240573	240573	5:g.240573G>A	ClinGen:CA10578631	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1534C>T (p.Arg512Ter)	6389	SDHA	Pathogenic/Likely pathogenic	748089700	RCV000411416\|RCV000578965\|RCV000684799\|RCV000566844\|RCV002285327\|RCV002502437\|RCV003475994;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MedGen:C3661900\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672,	5	240574	240574	5:g.240574C>T	ClinGen:CA3173269	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1535G>A (p.Arg512Gln)	6389	SDHA	Uncertain significance	192818312	RCV000228640\|RCV000502879\|RCV002399826\|RCV002487068\|RCV003475071;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MedGen:CN169374\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011	5	240575	240575	5:g.240575G>A	ClinGen:CA3173270	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1541G>C (p.Ser514Thr)	6389	SDHA	Uncertain significance	587781729	RCV000129921\|RCV000791490;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240581	240581	NC_000005.9:g.240581G>C	ClinGen:CA165356	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1541G>A (p.Ser514Asn)	6389	SDHA	Uncertain significance	587781729	RCV001241335;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240581	240581	5:g.240581G>A	-
NM_004168.4(SDHA):c.1542C>G (p.Ser514Arg)	6389	SDHA	Uncertain significance	1301221379	RCV001340709\|RCV002402942;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	240582	240582	240582	-
NM_004168.4(SDHA):c.1543A>G (p.Met515Val)	6389	SDHA	Uncertain significance	1736069297	RCV001299585\|RCV002402832;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	240583	240583	240583	-
NM_004168.4(SDHA):c.1545G>T (p.Met515Ile)	6389	SDHA	Uncertain significance	1736069479	RCV001323905;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240585	240585	240585	-
NM_004168.4(SDHA):c.1545G>A (p.Met515Ile)	6389	SDHA	Uncertain significance	-1	RCV002797179\|RCV003167805;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	240585	240585	NC_000005.9:g.240585G>A	-
NM_004168.4(SDHA):c.1547dup (p.Lys517fs)	6389	SDHA	Pathogenic	1554000378	RCV000649407;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240586	240587	5:g.240586_240587insA	ClinGen:CA658796492	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1546C>G (p.Gln516Glu)	6389	SDHA	Uncertain significance	1251348764	RCV000691589;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240586	240586	5:g.240586C>G	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1549_1551dup (p.Lys517dup)	6389	SDHA	Uncertain significance	1736070159	RCV001225383\|RCV003294077;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	240586	240587	5:g.240586_240587insAGA	-
NM_004168.4(SDHA):c.1547A>G (p.Gln516Arg)	6389	SDHA	Uncertain significance	981171929	RCV000793250\|RCV002256503\|RCV003148864;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	5	240587	240587	5:g.240587A>G	-
NM_004168.4(SDHA):c.1548G>A (p.Gln516=)	6389	SDHA	Likely benign	2126603098	RCV002149706;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	240588	240588	240588	-
NM_004168.4(SDHA):c.1549A>G (p.Lys517Glu)	6389	SDHA	Conflicting interpretations of pathogenicity	786205210	RCV000231483\|RCV002259327;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	240589	240589	NC_000005.9:g.240589A>G	ClinGen:CA358607,ClinVar:190221	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1551G>A (p.Lys517=)	6389	SDHA	Uncertain significance	772822136	RCV001999666\|RCV002398097;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	240591	240591	240591	-
NM_004168.4(SDHA):c.1551+1G>A	6389	SDHA	Conflicting interpretations of pathogenicity	759806010	RCV001041775\|RCV003160278;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	240592	240592	5:g.240592G>A	-
NM_004168.4(SDHA):c.1551+3A>G	6389	SDHA	Conflicting interpretations of pathogenicity	767596385	RCV001202435\|RCV002402577;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	240594	240594	5:g.240594A>G	-
NM_004168.4(SDHA):c.1551+4A>G	6389	SDHA	Conflicting interpretations of pathogenicity	928294715	RCV000649432\|RCV001012124\|RCV000606754;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN169374	5	240595	240595	5:g.240595A>G	ClinGen:CA112829820	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1551+4A>T	6389	SDHA	Uncertain significance	928294715	RCV001303372;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240595	240595	240595	-
NM_004168.4(SDHA):c.1551+5G>C	6389	SDHA	Uncertain significance	2126603143	RCV001912401;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	240596	240596	240596	-
NM_004168.4(SDHA):c.1551+6A>G	6389	SDHA	Uncertain significance	369507726	RCV000557246;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	240597	240597	5:g.240597A>G	ClinGen:CA3173274	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1551+7G>C	6389	SDHA	Likely benign	760796714	RCV001397090;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240598	240598	5:g.240598G>C	ClinGen:CA3173275	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1551+7G>A	6389	SDHA	Likely benign	760796714	RCV000933687;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	240598	240598	5:g.240598G>A	-
NM_004168.4(SDHA):c.1551+9C>T	6389	SDHA	Likely benign	2126603158	RCV002136967;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	240600	240600	240600	-
NM_004168.4(SDHA):c.1551+11G>C	6389	SDHA	Likely benign	-1	RCV003066243;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240602	240602	NC_000005.9:g.240602G>C	-
NM_004168.4(SDHA):c.1551+12G>A	6389	SDHA	Likely benign	-1	RCV003051210;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240603	240603	NC_000005.9:g.240603G>A	-
NM_004168.4(SDHA):c.1551+16C>T	6389	SDHA	Benign/Likely benign	184954254	RCV000435576\|RCV001511158\|RCV001528986\|RCV002502505;	N	MedGen:CN169374\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MedGen:C3661900\|MONDO:MONDO:0031006,MedGen:C5543254,OMIM:619259; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011,	5	240607	240607	5:g.240607C>T	ClinGen:CA3173278	CN169374 not specified;
NM_004168.4(SDHA):c.1551+17G>A	6389	SDHA	Likely benign	376232883	RCV002086990;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240608	240608	240608	-
NM_004168.4(SDHA):c.1551+18C>T	6389	SDHA	Likely benign	2126603212	RCV002080673;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240609	240609	240609	-
NM_004168.4(SDHA):c.1551+18C>A	6389	SDHA	Likely benign	-1	RCV003007590;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	240609	240609	NC_000005.9:g.240609C>A	-
NM_004168.4(SDHA):c.1552-173_1585dup	6389	SDHA	Uncertain significance	1736773597	RCV001325808;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	250933	250934	250933	-
NM_004168.4(SDHA):c.1552-20A>C	6389	SDHA	Likely benign	1378314484	RCV002117217;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251087	251087	251087	-
NM_004168.4(SDHA):c.1552-20A>G	6389	SDHA	Likely benign	1378314484	RCV002172712;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251087	251087	251087	-
NM_004168.4(SDHA):c.1552-18T>G	6389	SDHA	Likely benign	2126631828	RCV002093037;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	251089	251089	251089	-
NM_004168.4(SDHA):c.1552-16A>G	6389	SDHA	Likely benign	1418838846	RCV001921073;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251091	251091	251091	-
NM_004168.4(SDHA):c.1552-15T>C	6389	SDHA	Likely benign	543628983	RCV000601012\|RCV002066523;	N	MedGen:CN169374\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	251092	251092	5:g.251092T>C	ClinGen:CA3173294	CN169374 not specified;
NM_004168.4(SDHA):c.1552-14A>G	6389	SDHA	Likely benign	762315793	RCV002098693;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251093	251093	251093	-
NM_004168.4(SDHA):c.1552-13T>C	6389	SDHA	Likely benign	1280763236	RCV002081115;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	251094	251094	251094	-
NM_004168.4(SDHA):c.1552-12T>C	6389	SDHA	Likely benign	2126631871	RCV002147170;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	251095	251095	251095	-
NM_004168.4(SDHA):c.1552-10T>G	6389	SDHA	Uncertain significance	1736784473	RCV001064929;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251097	251097	5:g.251097T>G	-
NM_004168.4(SDHA):c.1552-9G>A	6389	SDHA	Likely benign	765624219	RCV001452964;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251098	251098	251098	-
NM_004168.4(SDHA):c.1552-7G>A	6389	SDHA	Likely benign	1351792129	RCV001488057;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251100	251100	5:g.251100G>A	-
NM_004168.4(SDHA):c.1552-7G>T	6389	SDHA	Likely benign	1351792129	RCV000983788;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	251100	251100	5:g.251100G>T	-
NM_004168.4(SDHA):c.1552-7G>C	6389	SDHA	Likely benign	1351792129	RCV001436516;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251100	251100	251100	-
NM_004168.4(SDHA):c.1552-6C>T	6389	SDHA	Likely benign	2126631902	RCV001506571;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251101	251101	251101	-
NM_004168.4(SDHA):c.1552-3_1552-2del	6389	SDHA	Uncertain significance	2126631914	RCV002005047;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	251102	251103	251101	-
NM_004168.4(SDHA):c.1552-3C>T	6389	SDHA	Uncertain significance	1222778933	RCV000649455\|RCV001012127;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251104	251104	5:g.251104C>T	ClinGen:CA557102395	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1552T>C (p.Ser518Pro)	6389	SDHA	Uncertain significance	2126631929	RCV001371441;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	251107	251107	251107	-
NM_004168.4(SDHA):c.1552T>A (p.Ser518Thr)	6389	SDHA	Uncertain significance	-1	RCV002667585;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251107	251107	NC_000005.9:g.251107T>A	-
NM_004168.4(SDHA):c.1553C>T (p.Ser518Leu)	6389	SDHA	Uncertain significance	2126631937	RCV001907865;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	251108	251108	251108	-
NM_004168.4(SDHA):c.1555A>G (p.Met519Val)	6389	SDHA	Uncertain significance	2126631942	RCV001974203\|RCV002398040;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251110	251110	251110	-
NM_004168.4(SDHA):c.1558C>T (p.Gln520Ter)	6389	SDHA	Pathogenic	2126631964	RCV001924318;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251113	251113	251113	-
NM_004168.4(SDHA):c.1560A>G (p.Gln520=)	6389	SDHA	Likely benign	1261025402	RCV001415360;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251115	251115	5:g.251115A>G	-
NM_004168.4(SDHA):c.1564_1566del (p.His522del)	6389	SDHA	Uncertain significance	1325342549	RCV001062225\|RCV002402440\|RCV003473682;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	251117	251119	5:g.251117_251119del	-
NM_004168.4(SDHA):c.1564C>T (p.His522Tyr)	6389	SDHA	Uncertain significance	-1	RCV003034962;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251119	251119	NC_000005.9:g.251119C>T	-
NM_004168.4(SDHA):c.1565A>G (p.His522Arg)	6389	SDHA	Uncertain significance	-1	RCV002405500\|RCV003100725;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251120	251120	251120	-
NM_004168.4(SDHA):c.1567G>T (p.Ala523Ser)	6389	SDHA	Uncertain significance	1554001820	RCV000649393;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251122	251122	NC_000005.9:g.251122G>T	ClinGen:CA358998442	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1568C>A (p.Ala523Asp)	6389	SDHA	Uncertain significance	1736785630	RCV001234164;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251123	251123	5:g.251123C>A	-
NM_004168.4(SDHA):c.1568C>G (p.Ala523Gly)	6389	SDHA	Uncertain significance	1736785630	RCV001346982\|RCV002404817\|RCV003154005;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	5	251123	251123	251123	-
NM_004168.4(SDHA):c.1568C>T (p.Ala523Val)	6389	SDHA	Uncertain significance	1736785630	RCV001920893\|RCV002397907;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251123	251123	251123	-
NM_004168.4(SDHA):c.1569T>C (p.Ala523=)	6389	SDHA	Benign/Likely benign	150192376	RCV000445091\|RCV000458596\|RCV000566664;	N	MedGen:CN169374\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251124	251124	5:g.251124T>C	ClinGen:CA3173297	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1570G>T (p.Ala524Ser)	6389	SDHA	Uncertain significance	-1	RCV002876913;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251125	251125	NC_000005.9:g.251125G>T	-
NM_004168.4(SDHA):c.1571C>T (p.Ala524Val)	6389	SDHA	Pathogenic/Likely pathogenic	137852767	RCV000009282\|RCV000520939\|RCV000649458\|RCV002399314\|RCV003473061;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MedGen:C3661900\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672,O	5	251126	251126	5:g.251126C>T	ClinGen:CA119880,UniProtKB:P31040#VAR_016878,OMIM:600857.0002	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1572C>G (p.Ala524=)	6389	SDHA	Likely benign	185679709	RCV000550313\|RCV002404525;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251127	251127	NC_000005.9:g.251127C>G	ClinGen:CA442657263	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1572C>T (p.Ala524=)	6389	SDHA	Likely benign	185679709	RCV000954797\|RCV002400113;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251127	251127	5:g.251127C>T	-
NM_004168.4(SDHA):c.1573G>A (p.Val525Met)	6389	SDHA	Uncertain significance	979815942	RCV000558310\|RCV001012216\|RCV003238773;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	5	251128	251128	NC_000005.9:g.251128G>A	ClinGen:CA112783487	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1575G>A (p.Val525=)	6389	SDHA	Likely benign	766757653	RCV001400092;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251130	251130	5:g.251130G>A	-
NM_004168.4(SDHA):c.1579del (p.Arg527fs)	6389	SDHA	Pathogenic/Likely pathogenic	1579437839	RCV000809642\|RCV002390625\|RCV002501099\|RCV003316813;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; M	5	251133	251133	5:g.251133_251133del	-
NM_004168.4(SDHA):c.1578C>T (p.Phe526=)	6389	SDHA	Likely benign	2126632042	RCV001400009;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251133	251133	251133	-
NM_004168.4(SDHA):c.1578C>A (p.Phe526Leu)	6389	SDHA	Uncertain significance	2126632042	RCV002042300\|RCV002397778\|RCV003475115;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	251133	251133	251133	-
NM_004168.4(SDHA):c.1579C>T (p.Arg527Cys)	6389	SDHA	Uncertain significance	138723511	RCV000477361\|RCV001012271\|RCV001764450;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	5	251134	251134	NC_000005.9:g.251134C>T	ClinGen:CA3173300	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1580G>A (p.Arg527His)	6389	SDHA	Conflicting interpretations of pathogenicity	766352407	RCV000287976\|RCV000352061\|RCV000396802\|RCV000461471\|RCV001012256\|RCV003475935;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0017366,MedGen:C1708353, Orphanet:29072\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100	5	251135	251135	NC_000005.9:g.251135G>A	ClinGen:CA3173301	C0023264 256000 Leigh syndrome;
NM_004168.4(SDHA):c.1581T>C (p.Arg527=)	6389	SDHA	Likely benign	2126632074	RCV002155140\|RCV002398249;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251136	251136	251136	-
NM_004168.4(SDHA):c.1584G>C (p.Val528=)	6389	SDHA	Likely benign	-1	RCV002898920;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251139	251139		-
NM_004168.4(SDHA):c.1584G>T (p.Val528=)	6389	SDHA	Likely benign	-1	RCV002899383;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251139	251139		-
NM_004168.4(SDHA):c.1585G>C (p.Gly529Arg)	6389	SDHA	Uncertain significance	370291114	RCV000466069\|RCV001012294\|RCV003476120;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	251140	251140	NC_000005.9:g.251140G>C	ClinGen:CA3173302	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1586G>C (p.Gly529Ala)	6389	SDHA	Uncertain significance	2126632088	RCV001864447;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	251141	251141	251141	-
NM_004168.4(SDHA):c.1590C>T (p.Ser530=)	6389	SDHA	Likely benign	1060503701	RCV000457655\|RCV001012331;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251145	251145	5:g.251145C>T	ClinGen:CA16611975	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1591G>A (p.Val531Met)	6389	SDHA	Uncertain significance	371056571	RCV000193391\|RCV000226464\|RCV000410380\|RCV000573905\|RCV001093473;	N	MedGen:CN169374\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672,	5	251146	251146	5:g.251146G>A	ClinGen:CA206847	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1591G>T (p.Val531Leu)	6389	SDHA	Uncertain significance	371056571	RCV001220419\|RCV002402664\|RCV002484197;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	5	251146	251146	5:g.251146G>T	-
NM_004168.4(SDHA):c.1593G>A (p.Val531=)	6389	SDHA	Likely benign	2126632110	RCV001489340;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251148	251148	251148	-
NM_004168.4(SDHA):c.1596G>A (p.Leu532=)	6389	SDHA	Likely benign	1449742263	RCV000926023\|RCV002400029;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251151	251151	5:g.251151G>A	-
NM_004168.4(SDHA):c.1596G>T (p.Leu532Phe)	6389	SDHA	Uncertain significance	1449742263	RCV001208709\|RCV002402614;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251151	251151	5:g.251151G>T	-
NM_004168.4(SDHA):c.1597C>G (p.Gln533Glu)	6389	SDHA	Uncertain significance	149367009	RCV000469150\|RCV001012355\|RCV002298608\|RCV003476131;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642	5	251152	251152	NC_000005.9:g.251152C>G	ClinGen:CA3173303	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1598A>T (p.Gln533Leu)	6389	SDHA	Uncertain significance	1395387473	RCV001056476;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251153	251153	5:g.251153A>T	-
NM_004168.4(SDHA):c.1598AAG[1] (p.Glu534del)	6389	SDHA	Uncertain significance	1736788779	RCV001241320\|RCV003166504;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251153	251155	5:g.251153_251155del	-
NM_004168.4(SDHA):c.1598A>C (p.Gln533Pro)	6389	SDHA	Uncertain significance	1395387473	RCV001342503;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251153	251153	251153	-
NM_004168.4(SDHA):c.1599A>G (p.Gln533=)	6389	SDHA	Likely benign	1407806818	RCV000534189\|RCV002404526;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251154	251154	NC_000005.9:g.251154A>G	ClinGen:CA442657282	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1600G>A (p.Glu534Lys)	6389	SDHA	Uncertain significance	-1	RCV002991673;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251155	251155	NC_000005.9:g.251155G>A	-
NM_004168.4(SDHA):c.1602A>G (p.Glu534=)	6389	SDHA	Likely benign	2126632157	RCV001487705;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251157	251157	251157	-
NM_004168.4(SDHA):c.1603G>T (p.Gly535Cys)	6389	SDHA	Uncertain significance	777622021	RCV000551366\|RCV002404527;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251158	251158	NC_000005.9:g.251158G>T	ClinGen:CA3173304	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1604G>C (p.Gly535Ala)	6389	SDHA	Uncertain significance	1736789524	RCV001232735\|RCV003473800;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	251159	251159	5:g.251159G>C	-
NM_004168.4(SDHA):c.1605T>C (p.Gly535=)	6389	SDHA	Likely benign	1219265731	RCV001422966;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251160	251160	251160	-
NM_004168.4(SDHA):c.1607G>A (p.Cys536Tyr)	6389	SDHA	Uncertain significance	1736789855	RCV001242993;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251162	251162	5:g.251162G>A	-
NM_004168.4(SDHA):c.1607G>T (p.Cys536Phe)	6389	SDHA	Uncertain significance	-1	RCV002301629;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251162	251162	251162	-
NM_004168.4(SDHA):c.1608T>A (p.Cys536Ter)	6389	SDHA	Pathogenic	-1	RCV003015540;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251163	251163	NC_000005.9:g.251163T>A	-
NM_004168.4(SDHA):c.1609G>A (p.Gly537Arg)	6389	SDHA	Uncertain significance	1736789994	RCV001345903\|RCV002395760\|RCV003473872;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	251164	251164	251164	-
NM_004168.4(SDHA):c.1615dup (p.Ile539fs)	6389	SDHA	Pathogenic/Likely pathogenic	1554001843	RCV000457642\|RCV003456080\|RCV003476128;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	251166	251167	NC_000005.9:g.251170dup	ClinGen:CA16611891	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1611G>A (p.Gly537=)	6389	SDHA	Likely benign	1060505009	RCV000457724\|RCV002402372;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251166	251166	NC_000005.9:g.251166G>A	ClinGen:CA16611976	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1614A>G (p.Lys538=)	6389	SDHA	Likely benign	1554001847	RCV000526113\|RCV002395447;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251169	251169	5:g.251169A>G	ClinGen:CA442657292	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1615A>G (p.Ile539Val)	6389	SDHA	Uncertain significance	-1	RCV003040695;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251170	251170	NC_000005.9:g.251170A>G	-
NM_004168.4(SDHA):c.1616T>G (p.Ile539Ser)	6389	SDHA	Uncertain significance	749219128	RCV000538676\|RCV002395448;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251171	251171	5:g.251171T>G	ClinGen:CA3173305	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1617C>T (p.Ile539=)	6389	SDHA	Likely benign	2126632215	RCV002208831\|RCV003303731;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251172	251172	251172	-
NM_004168.4(SDHA):c.1620C>T (p.Ser540=)	6389	SDHA	Likely benign	-1	RCV002886269;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251175	251175		-
NM_004168.4(SDHA):c.1621A>G (p.Lys541Glu)	6389	SDHA	Uncertain significance	1736791200	RCV001218244;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251176	251176	5:g.251176A>G	-
NM_004168.4(SDHA):c.1623G>A (p.Lys541=)	6389	SDHA	Conflicting interpretations of pathogenicity	35502109	RCV000239362\|RCV000242066\|RCV000569690\|RCV001081440\|RCV001153642\|RCV001153643\|RCV001153641\|RCV003316319;	N	MedGen:C3661900\|MedGen:CN169374\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0009723,MedGen:C002	5	251178	251178	NC_000005.9:g.251178G>A	ClinGen:CA3173306	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1625T>C (p.Leu542Pro)	6389	SDHA	Uncertain significance	1233761838	RCV001336640\|RCV001865854\|RCV002402923;	N	MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251180	251180	251180	-
NM_004168.4(SDHA):c.1626C>T (p.Leu542=)	6389	SDHA	Likely benign	1269358534	RCV001428428\|RCV002405000;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251181	251181	251181	-
NM_004168.4(SDHA):c.1626C>G (p.Leu542=)	6389	SDHA	Likely benign	-1	RCV003052454;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251181	251181		-
NM_004168.4(SDHA):c.1627T>C (p.Tyr543His)	6389	SDHA	Uncertain significance	1339009840	RCV000551034\|RCV001012481\|RCV002491085;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072;	5	251182	251182	NC_000005.9:g.251182T>C	ClinGen:CA358998693	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1628A>G (p.Tyr543Cys)	6389	SDHA	Uncertain significance	778670859	RCV001981564\|RCV002397988;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251183	251183	251183	-
NM_004168.4(SDHA):c.1629T>C (p.Tyr543=)	6389	SDHA	Likely benign	747249998	RCV000459700\|RCV000569829;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251184	251184	NC_000005.9:g.251184T>C	ClinGen:CA3173308	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1629T>G (p.Tyr543Ter)	6389	SDHA	Pathogenic	747249998	RCV000649408\|RCV001535631;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0017366,MedGen:C1708353, Orphanet:29072	5	251184	251184	5:g.251184T>G	ClinGen:CA358998711	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1630G>A (p.Gly544Arg)	6389	SDHA	Uncertain significance	1338347881	RCV001204999;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251185	251185	5:g.251185G>A	-
NM_004168.4(SDHA):c.1631G>A (p.Gly544Glu)	6389	SDHA	Uncertain significance	2126632293	RCV001945900\|RCV002397928;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251186	251186	251186	-
NM_004168.4(SDHA):c.1633G>A (p.Asp545Asn)	6389	SDHA	Uncertain significance	1736792773	RCV001308861;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251188	251188	251188	-
NM_004168.4(SDHA):c.1633G>T (p.Asp545Tyr)	6389	SDHA	Uncertain significance	1736792773	RCV001984856;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251188	251188	251188	-
NM_004168.4(SDHA):c.1638A>C (p.Leu546=)	6389	SDHA	Likely benign	1041963	RCV001484156\|RCV002399932;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251193	251193	5:g.251193A>C	-
NM_004168.4(SDHA):c.1639A>C (p.Lys547Gln)	6389	SDHA	Uncertain significance	-1	RCV003085506;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251194	251194	NC_000005.9:g.251194A>C	-
NM_004168.4(SDHA):c.1640A>G (p.Lys547Arg)	6389	SDHA	Uncertain significance	1561010407	RCV000693477\|RCV003338734\|RCV003472210;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	251195	251195	NC_000005.9:g.251195A>G	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1641G>C (p.Lys547Asn)	6389	SDHA	Uncertain significance	1267429398	RCV001988310;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	251196	251196	251196	-
NM_004168.4(SDHA):c.1643A>G (p.His548Arg)	6389	SDHA	Uncertain significance	-1	RCV002603351;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251198	251198	NC_000005.9:g.251198A>G	-
NM_004168.4(SDHA):c.1644C>T (p.His548=)	6389	SDHA	Likely benign	1126427	RCV000463554\|RCV002395139;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251199	251199	NC_000005.9:g.251199C>T	ClinGen:CA3173309	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1646T>C (p.Leu549Pro)	6389	SDHA	Uncertain significance	1579438155	RCV000821834;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251201	251201	5:g.251201T>C	-
NM_004168.4(SDHA):c.1648A>C (p.Lys550Gln)	6389	SDHA	Uncertain significance	1400219619	RCV000697520;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251203	251203	NC_000005.9:g.251203A>C	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1650G>A (p.Lys550=)	6389	SDHA	Likely benign	1359705251	RCV001422453\|RCV003284315;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251205	251205	251205	-
NM_004168.4(SDHA):c.1651A>G (p.Thr551Ala)	6389	SDHA	Uncertain significance	1200051286	RCV001060536;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251206	251206	5:g.251206A>G	-
NM_004168.4(SDHA):c.1652C>T (p.Thr551Met)	6389	SDHA	Uncertain significance	181238392	RCV000458208\|RCV000569746\|RCV000662939\|RCV002475896;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|	5	251207	251207	NC_000005.9:g.251207C>T	ClinGen:CA3173310	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1653G>A (p.Thr551=)	6389	SDHA	Likely benign	761927291	RCV000229586\|RCV000565314;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251208	251208	5:g.251208G>A	ClinGen:CA3173311	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1654T>G (p.Phe552Val)	6389	SDHA	Uncertain significance	1736795269	RCV001242634\|RCV002402770;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251209	251209	5:g.251209T>G	-
NM_004168.4(SDHA):c.1656C>T (p.Phe552=)	6389	SDHA	Likely benign	1170030451	RCV000573955\|RCV000864334;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251211	251211	NC_000005.9:g.251211C>T	ClinGen:CA442657314	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1656del (p.Phe552fs)	6389	SDHA	Pathogenic	1736795573	RCV001041854;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	251211	251211	5:g.251211_251211del	-
NM_004168.4(SDHA):c.1658_1661del (p.Asp553fs)	6389	SDHA	Pathogenic	2126632404	RCV001956414;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251211	251214	251210	-
NM_004168.4(SDHA):c.1657G>A (p.Asp553Asn)	6389	SDHA	Uncertain significance	769882609	RCV000233573\|RCV001012585\|RCV001762530\|RCV003475072;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642	5	251212	251212	NC_000005.9:g.251212G>A	ClinGen:CA3173312	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1658A>C (p.Asp553Ala)	6389	SDHA	Uncertain significance	1060503723	RCV000472549;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	251213	251213	NC_000005.9:g.251213A>C	ClinGen:CA16611893	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1659C>T (p.Asp553=)	6389	SDHA	Likely benign	-1	RCV002819191;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251214	251214		-
NM_004168.4(SDHA):c.1660C>T (p.Arg554Trp)	6389	SDHA	Conflicting interpretations of pathogenicity	9809219	RCV000009281\|RCV000456631\|RCV000573113\|RCV000790927\|RCV001818148\|RCV003315222\|RCV003473060;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|M	5	251215	251215	NC_000005.9:g.251215C>T	ClinGen:CA119879,UniProtKB:P31040#VAR_002449,OMIM:600857.0001	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1660C>A (p.Arg554=)	6389	SDHA	Likely benign	9809219	RCV002217905\|RCV002398197;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251215	251215	251215	-
NM_004168.4(SDHA):c.1661G>A (p.Arg554Gln)	6389	SDHA	Conflicting interpretations of pathogenicity	376391115	RCV000226282\|RCV000565244\|RCV000663186\|RCV001153644\|RCV001153645\|RCV001153646\|RCV002253311\|RCV002267990;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|	5	251216	251216	NC_000005.9:g.251216G>A	ClinGen:CA3173313	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1661G>T (p.Arg554Leu)	6389	SDHA	Uncertain significance	376391115	RCV001203540;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251216	251216	5:g.251216G>T	-
NM_004168.4(SDHA):c.1662G>T (p.Arg554=)	6389	SDHA	Uncertain significance	1579438241	RCV000821769;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251217	251217	5:g.251217G>T	-
NM_004168.4(SDHA):c.1662G>C (p.Arg554=)	6389	SDHA	Uncertain significance	1579438241	RCV001236409;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251217	251217	5:g.251217G>C	-
NM_004168.4(SDHA):c.1663G>C (p.Gly555Arg)	6389	SDHA	Uncertain significance	1392860800	RCV000703879\|RCV002397470;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251218	251218	5:g.251218G>C	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1663G>A (p.Gly555Arg)	6389	SDHA	Uncertain significance	1392860800	RCV001968186;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251218	251218	251218	-
NM_004168.4(SDHA):c.1663+1G>T	6389	SDHA	Pathogenic/Likely pathogenic	766667009	RCV000218973\|RCV000466792\|RCV002500730\|RCV003229821\|RCV003475016;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; M	5	251219	251219	5:g.251219G>T	ClinGen:CA3173314	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1663+1G>A	6389	SDHA	Pathogenic/Likely pathogenic	766667009	RCV001229903\|RCV002402720\|RCV002480754\|RCV003336351;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; M	5	251219	251219	5:g.251219G>A	-
NM_004168.4(SDHA):c.1663+1G>C	6389	SDHA	Pathogenic	-1	RCV002885195;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251219	251219	NC_000005.9:g.251219G>C	-
NM_004168.4(SDHA):c.1663+3G>C	6389	SDHA	Conflicting interpretations of pathogenicity	751904543	RCV000700223\|RCV001799703\|RCV002397443;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|Human Phenotype Ontology:HP:0100723,MONDO:MONDO:0011719,MeSH:D046152,MedGen:C0238198,OMIM:606764, Orphanet:44890\|MONDO:MONDO:0015	5	251221	251221	5:g.251221G>C	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1663+5G>C	6389	SDHA	Conflicting interpretations of pathogenicity	1736797211	RCV001046874\|RCV003473632;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	251223	251223	5:g.251223G>C	-
NM_004168.4(SDHA):c.1663+6C>G	6389	SDHA	Uncertain significance	1736797323	RCV001225632;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251224	251224	5:g.251224C>G	-
NM_004168.4(SDHA):c.1663+7A>G	6389	SDHA	Conflicting interpretations of pathogenicity	1579438260	RCV000978101\|RCV003438642;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MedGen:C3661900	5	251225	251225	5:g.251225A>G	-
NM_004168.4(SDHA):c.1663+10C>G	6389	SDHA	Likely benign	-1	RCV003053612;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251228	251228	NC_000005.9:g.251228C>G	-
NM_004168.4(SDHA):c.1663+11A>C	6389	SDHA	Likely benign	1037190778	RCV002162145;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251229	251229	251229	-
NM_004168.4(SDHA):c.1663+17C>T	6389	SDHA	Likely benign	759291109	RCV002165500;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251235	251235	251235	-
NM_004168.4(SDHA):c.1663+19C>T	6389	SDHA	Likely benign	1214851392	RCV002092873;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251237	251237	251237	-
NM_004168.4(SDHA):c.1663+20T>C	6389	SDHA	Likely benign	1226482893	RCV002145150;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251238	251238	251238	-
NM_004168.4(SDHA):c.1664-20G>A	6389	SDHA	Uncertain significance	1310666225	RCV001970882;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	251433	251433	251433	-
NM_004168.4(SDHA):c.1664-19G>A	6389	SDHA	Likely benign	2126633052	RCV002114007;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251434	251434	251434	-
NM_004168.4(SDHA):c.1664-16C>G	6389	SDHA	Likely benign	763374204	RCV002198230;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	251437	251437	251437	-
NM_004168.4(SDHA):c.1664-11del	6389	SDHA	Benign	1561010692	RCV002127371;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	251438	251438	251437	-
NM_004168.4(SDHA):c.1664-13T>C	6389	SDHA	Likely benign	1057524514	RCV000423740\|RCV002525496;	N	MedGen:CN169374\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251440	251440	5:g.251440T>C	ClinGen:CA16604891	CN169374 not specified;
NM_004168.4(SDHA):c.1664-9dup	6389	SDHA	Likely benign	2126633086	RCV001470440;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	251443	251444	251443	-
NM_004168.4(SDHA):c.1664-10G>T	6389	SDHA	Likely benign	1736810726	RCV002165832;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251443	251443	251443	-
NM_004168.4(SDHA):c.1664-8G>A	6389	SDHA	Benign/Likely benign	199790689	RCV000118313\|RCV000205034\|RCV000312438\|RCV000367152\|RCV000396767\|RCV002477296\|RCV003315677;	N	MedGen:CN169374\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506\|MONDO:MONDO:0017366,MedGen:C1708353, Orphanet:29072\|	5	251445	251445	5:g.251445G>A	ClinGen:CA345541	C0023264 256000 Leigh syndrome;
NM_004168.4(SDHA):c.1664-5C>G	6389	SDHA	Likely benign	1211852182	RCV001905768;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	251448	251448	251448	-
NM_004168.4(SDHA):c.1664-4C>G	6389	SDHA	Conflicting interpretations of pathogenicity	774876028	RCV000527162\|RCV001012643;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251449	251449	5:g.251449C>G	ClinGen:CA658657412	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1664-4C>A	6389	SDHA	Conflicting interpretations of pathogenicity	774876028	RCV000871165\|RCV002399933;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251449	251449	5:g.251449C>A	-
NM_004168.4(SDHA):c.1664-4C>T	6389	SDHA	Likely benign	-1	RCV002403872\|RCV003097082;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251449	251449	251449	-
NM_004168.4(SDHA):c.1664-2A>G	6389	SDHA	Likely pathogenic	2126633124	RCV001379935\|RCV002404895;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251451	251451	251451	-
NM_004168.4(SDHA):c.1664-1G>A	6389	SDHA	Likely pathogenic	-1	RCV002796547;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251452	251452	NC_000005.9:g.251452G>A	-
NM_004168.4(SDHA):c.1664G>A (p.Gly555Glu)	6389	SDHA	Pathogenic	137852768	RCV000009286\|RCV000009284\|RCV001221088;	N	MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251453	251453	5:g.251453G>A	ClinGen:CA119883,UniProtKB:P31040#VAR_016879,OMIM:600857.0004	C3150898 613642 Dilated cardiomyopathy 1GG;
NM_004168.4(SDHA):c.1666A>G (p.Met556Val)	6389	SDHA	Uncertain significance	980397872	RCV000539477\|RCV002395449;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251455	251455	5:g.251455A>G	ClinGen:CA112783554	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1667T>C (p.Met556Thr)	6389	SDHA	Uncertain significance	1579438769	RCV001012629\|RCV001319900\|RCV003396598;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MedGen:CN169374	5	251456	251456	5:g.251456T>C	-
NM_004168.4(SDHA):c.1667T>A (p.Met556Lys)	6389	SDHA	Uncertain significance	1579438769	RCV001301625;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251456	251456	251456	-
NM_004168.4(SDHA):c.1668G>A (p.Met556Ile)	6389	SDHA	Uncertain significance	2126633148	RCV001979645;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	251457	251457	251457	-
NM_004168.4(SDHA):c.1671C>A (p.Val557=)	6389	SDHA	Likely benign	767963713	RCV001472004;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	251460	251460	251460	-
NM_004168.4(SDHA):c.1674G>T (p.Trp558Cys)	6389	SDHA	Uncertain significance	1561010726	RCV000705255\|RCV002397477;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251463	251463	5:g.251463G>T	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1677C>T (p.Asn559=)	6389	SDHA	Likely benign	2126633167	RCV002200848;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251466	251466	251466	-
NM_004168.4(SDHA):c.1678A>G (p.Thr560Ala)	6389	SDHA	Uncertain significance	1269114291	RCV001207335\|RCV002402603;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251467	251467	5:g.251467A>G	-
NM_004168.4(SDHA):c.1679C>T (p.Thr560Met)	6389	SDHA	Uncertain significance	775350508	RCV000649400\|RCV001012616\|RCV003313127\|RCV003472040;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642	5	251468	251468	NC_000005.9:g.251468C>T	ClinGen:CA3173334	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1680G>A (p.Thr560=)	6389	SDHA	Benign/Likely benign	1139449	RCV000118314\|RCV000162436\|RCV000298674\|RCV000353507\|RCV000398522\|RCV001513597\|RCV001705857\|RCV003315678;	N	MedGen:CN169374\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506\|MONDO:MONDO:0017366,MedGen:C1708353, Orphanet:29072\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:320	5	251469	251469	5:g.251469G>A	ClinGen:CA155146	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1680G>T (p.Thr560=)	6389	SDHA	Likely benign	1139449	RCV002156655;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251469	251469	251469	-
NM_004168.4(SDHA):c.1684C>A (p.Leu562Met)	6389	SDHA	Uncertain significance	1561010740	RCV000794345\|RCV002397577;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251473	251473	5:g.251473C>A	-
NM_004168.4(SDHA):c.1684C>T (p.Leu562=)	6389	SDHA	Likely benign	1561010740	RCV001501575;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	251473	251473	251473	-
NM_004168.4(SDHA):c.1684C>G (p.Leu562Val)	6389	SDHA	Uncertain significance	1561010740	RCV001997685\|RCV002407197;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251473	251473	251473	-
NM_004168.4(SDHA):c.1685T>C (p.Leu562Pro)	6389	SDHA	Uncertain significance	1736814018	RCV001224144;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251474	251474	5:g.251474T>C	-
NM_004168.4(SDHA):c.1686G>C (p.Leu562=)	6389	SDHA	Likely benign	1579438828	RCV001417522\|RCV002400036;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251475	251475	5:g.251475G>C	-
NM_004168.4(SDHA):c.1686G>T (p.Leu562=)	6389	SDHA	Likely benign	1579438828	RCV001475399;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251475	251475	251475	-
NM_004168.4(SDHA):c.1687G>A (p.Val563Met)	6389	SDHA	Uncertain significance	1736814459	RCV001059823\|RCV002409477;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251476	251476	5:g.251476G>A	-
NM_004168.4(SDHA):c.1687G>T (p.Val563Leu)	6389	SDHA	Uncertain significance	1736814459	RCV001051934\|RCV003307861;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251476	251476	5:g.251476G>T	-
NM_004168.4(SDHA):c.1689G>A (p.Val563=)	6389	SDHA	Likely benign	2126633222	RCV002077620\|RCV002407328;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251478	251478	251478	-
NM_004168.4(SDHA):c.1691A>G (p.Glu564Gly)	6389	SDHA	Uncertain significance	763529675	RCV001921775\|RCV003303421;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251480	251480	251480	-
NM_004168.4(SDHA):c.1692G>A (p.Glu564=)	6389	SDHA	Likely benign	368388954	RCV000952374\|RCV002400109;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251481	251481	5:g.251481G>A	-
NM_004168.4(SDHA):c.1692G>C (p.Glu564Asp)	6389	SDHA	Uncertain significance	368388954	RCV001045602;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	251481	251481	5:g.251481G>C	-
NM_004168.4(SDHA):c.1694C>A (p.Thr565Asn)	6389	SDHA	Uncertain significance	757176672	RCV000822013\|RCV002397721\|RCV002495177;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072;	5	251483	251483	5:g.251483C>A	-
NM_004168.4(SDHA):c.1694C>T (p.Thr565Ile)	6389	SDHA	Uncertain significance	757176672	RCV001318903\|RCV003339595;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251483	251483	251483	-
NM_004168.4(SDHA):c.1695C>G (p.Thr565=)	6389	SDHA	Likely benign	765113103	RCV001444944\|RCV002414062;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251484	251484	251484	-
NM_004168.4(SDHA):c.1696C>G (p.Leu566Val)	6389	SDHA	Uncertain significance	142936520	RCV000552092\|RCV002413604;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251485	251485	5:g.251485C>G	ClinGen:CA112783565	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1697T>G (p.Leu566Arg)	6389	SDHA	Uncertain significance	1579438883	RCV000797716\|RCV003225735;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	251486	251486	5:g.251486T>G	-
NM_004168.4(SDHA):c.1699G>A (p.Glu567Lys)	6389	SDHA	Uncertain significance	1736816371	RCV001325325;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251488	251488	251488	-
NM_004168.4(SDHA):c.1702C>G (p.Leu568Val)	6389	SDHA	Uncertain significance	1554001912	RCV000527972;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	251491	251491	NC_000005.9:g.251491C>G	ClinGen:CA359000014	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1707G>A (p.Gln569=)	6389	SDHA	Likely benign	959934068	RCV000567195\|RCV000922848;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251496	251496	5:g.251496G>A	ClinGen:CA112783567	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1708A>T (p.Asn570Tyr)	6389	SDHA	Uncertain significance	1561010778	RCV000704274;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251497	251497	NC_000005.9:g.251497A>T	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1710C>A (p.Asn570Lys)	6389	SDHA	Uncertain significance	-1	RCV002635034;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251499	251499	NC_000005.9:g.251499C>A	-
NM_004168.4(SDHA):c.1711C>G (p.Leu571Val)	6389	SDHA	Uncertain significance	1377424433	RCV001932947\|RCV002397908;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251500	251500	251500	-
NM_004168.4(SDHA):c.1712T>C (p.Leu571Pro)	6389	SDHA	Uncertain significance	1736817446	RCV001054131\|RCV002282442;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MedGen:CN169374	5	251501	251501	5:g.251501T>C	-
NM_004168.4(SDHA):c.1715T>G (p.Met572Arg)	6389	SDHA	Uncertain significance	1554001925	RCV000540559;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	251504	251504	5:g.251504T>G	ClinGen:CA359000079	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1715T>C (p.Met572Thr)	6389	SDHA	Uncertain significance	1554001925	RCV001370334\|RCV003169902;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251504	251504	251504	-
NM_004168.4(SDHA):c.1716dup (p.Leu573fs)	6389	SDHA	Pathogenic	-1	RCV002414754\|RCV003097158;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251504	251505	251504	-
NM_004168.4(SDHA):c.1717C>G (p.Leu573Val)	6389	SDHA	Uncertain significance	1445945083	RCV000702338\|RCV002397461\|RCV003153817\|RCV003472238;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|	5	251506	251506	NC_000005.9:g.251506C>G	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1719G>T (p.Leu573=)	6389	SDHA	Likely benign	-1	RCV003090804;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251508	251508		-
NM_004168.4(SDHA):c.1721G>A (p.Cys574Tyr)	6389	SDHA	Uncertain significance	2126633379	RCV001983803;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251510	251510	251510	-
NM_004168.4(SDHA):c.1723G>A (p.Ala575Thr)	6389	SDHA	Uncertain significance	1301370839	RCV000705288;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251512	251512	5:g.251512G>A	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1724C>T (p.Ala575Val)	6389	SDHA	Uncertain significance	750327309	RCV000467983\|RCV000487393\|RCV000572994\|RCV000663257\|RCV002268094\|RCV003476132;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165	5	251513	251513	NC_000005.9:g.251513C>T	ClinGen:CA3173339	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1725G>A (p.Ala575=)	6389	SDHA	Conflicting interpretations of pathogenicity	758252610	RCV000466412\|RCV000561801\|RCV001156241\|RCV001156242\|RCV001156240;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0017366,MedGen:C1708353, Orphanet:29072\|MONDO:MONDO:	5	251514	251514	NC_000005.9:g.251514G>A	ClinGen:CA3173340	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1725G>T (p.Ala575=)	6389	SDHA	Likely benign	758252610	RCV002205101\|RCV002398186;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251514	251514	251514	-
NM_004168.4(SDHA):c.1727T>C (p.Leu576Pro)	6389	SDHA	Uncertain significance	1318046349	RCV000700734\|RCV001157918\|RCV001156243\|RCV001157917\|RCV002406623;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0017366,MedGen:C1708353, Orphanet:29072\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:000	5	251516	251516	5:g.251516T>C	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1728G>A (p.Leu576=)	6389	SDHA	Likely benign	1736819188	RCV001464556\|RCV002405090;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251517	251517	251517	-
NM_004168.4(SDHA):c.1733C>A (p.Thr578Asn)	6389	SDHA	Uncertain significance	1349207461	RCV001969208;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251522	251522	251522	-
NM_004168.4(SDHA):c.1733C>T (p.Thr578Ile)	6389	SDHA	Uncertain significance	1349207461	RCV002043820\|RCV002398121;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251522	251522	251522	-
NM_004168.4(SDHA):c.1734C>G (p.Thr578=)	6389	SDHA	Likely benign	748328205	RCV001012943\|RCV001417433;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251523	251523	NC_000005.9:g.251523C>G	ClinGen:CA3173342	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1735A>G (p.Ile579Val)	6389	SDHA	Uncertain significance	1042052	RCV001301482;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251524	251524	251524	-
NM_004168.4(SDHA):c.1736T>C (p.Ile579Thr)	6389	SDHA	Uncertain significance	1323205068	RCV000804084;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251525	251525	5:g.251525T>C	-
NM_004168.4(SDHA):c.1737C>T (p.Ile579=)	6389	SDHA	Likely benign	201454617	RCV000475760\|RCV001012952\|RCV001082233\|RCV003316633;	N	MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165	5	251526	251526	NC_000005.9:g.251526C>T	ClinGen:CA3173343	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1738T>C (p.Tyr580His)	6389	SDHA	Uncertain significance	1042056	RCV000649423\|RCV002397290;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251527	251527	5:g.251527T>C	ClinGen:CA359000197	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1739A>G (p.Tyr580Cys)	6389	SDHA	Uncertain significance	372707443	RCV001012930\|RCV001234032;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251528	251528	5:g.251528A>G	-
NM_004168.4(SDHA):c.1739A>T (p.Tyr580Phe)	6389	SDHA	Uncertain significance	-1	RCV002304817\|RCV002400430;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251528	251528	251528	-
NM_004168.4(SDHA):c.1740C>T (p.Tyr580=)	6389	SDHA	Likely benign	3181540	RCV000574909\|RCV000649487;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251529	251529	5:g.251529C>T	ClinGen:CA3173345	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1741G>A (p.Gly581Arg)	6389	SDHA	Likely pathogenic	771111180	RCV000693056\|RCV001012918\|RCV001799698;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|Human Phenotype Ontology:HP:0100723,MONDO:MONDO:0011719,MeSH:D0	5	251530	251530	5:g.251530G>A	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1741G>T (p.Gly581Ter)	6389	SDHA	Pathogenic	-1	RCV002834957;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251530	251530	NC_000005.9:g.251530G>T	-
NM_004168.4(SDHA):c.1743_1744del (p.Ala582fs)	6389	SDHA	Pathogenic	2126633505	RCV002002449;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	251531	251532	251530	-
NM_004168.4(SDHA):c.1744G>C (p.Ala582Pro)	6389	SDHA	Uncertain significance	1736821952	RCV001351177\|RCV002404833;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251533	251533	251533	-
NM_004168.4(SDHA):c.1750G>A (p.Ala584Thr)	6389	SDHA	Uncertain significance	878854629	RCV000230255;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251539	251539	NC_000005.9:g.251539G>A	ClinGen:CA10582431	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1751C>T (p.Ala584Val)	6389	SDHA	Conflicting interpretations of pathogenicity	201068049	RCV000232844\|RCV000419445\|RCV000564512\|RCV003475073;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642	5	251540	251540	5:g.251540C>T	ClinGen:CA3173347	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1751_1752inv (p.Ala584Val)	6389	SDHA	Uncertain significance	-1	RCV001239330;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251540	251541	NC_000005.9:g.251540_251541inv	-
NM_004168.4(SDHA):c.1752A>G (p.Ala584=)	6389	SDHA	Benign	13070	RCV000118315\|RCV000162485\|RCV000268103\|RCV000323384\|RCV000359489\|RCV001513598\|RCV001705858\|RCV003315679;	N	MedGen:CN169374\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0017366,MedGen:C1708353, Orphanet:2907	5	251541	251541	5:g.251541A>G	ClinGen:CA155148	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1752_1753inv (p.Arg585Trp)	6389	SDHA	Pathogenic	-1	RCV000689287;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251541	251542	NC_000005.9:g.251541_251542inv	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1753C>T (p.Arg585Trp)	6389	SDHA	Conflicting interpretations of pathogenicity	200397144	RCV000148027\|RCV000163558\|RCV000464783\|RCV000762143\|RCV000765834\|RCV001824123\|RCV003474794;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|	5	251542	251542	NC_000005.9:g.251542C>T	ClinGen:CA188615,OMIM:600857.0009	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1754G>A (p.Arg585Gln)	6389	SDHA	Conflicting interpretations of pathogenicity	752360961	RCV000227812\|RCV000410930\|RCV001013022\|RCV001799642\|RCV003475074;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|	5	251543	251543	5:g.251543G>A	ClinGen:CA3173348	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1755_1759del (p.Lys586fs)	6389	SDHA	Pathogenic	1561010916	RCV001899180;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251543	251547	251542	-
NM_004168.4(SDHA):c.1755G>A (p.Arg585=)	6389	SDHA	Likely benign	760254364	RCV001460934;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251544	251544	251544	-
NM_004168.4(SDHA):c.1756A>G (p.Lys586Glu)	6389	SDHA	Uncertain significance	1736823607	RCV001303025;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251545	251545	251545	-
NM_004168.4(SDHA):c.1758G>A (p.Lys586=)	6389	SDHA	Likely benign	1554001953	RCV001459358;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251547	251547	251547	-
NM_004168.4(SDHA):c.1759G>A (p.Glu587Lys)	6389	SDHA	Uncertain significance	1554001954	RCV000649395;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251548	251548	5:g.251548G>A	ClinGen:CA359000305	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1761G>A (p.Glu587=)	6389	SDHA	Likely benign	2126633619	RCV001396044\|RCV002413937;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251550	251550	251550	-
NM_004168.4(SDHA):c.1763C>T (p.Ser588Leu)	6389	SDHA	Uncertain significance	1579439198	RCV000806707;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251552	251552	5:g.251552C>T	-
NM_004168.4(SDHA):c.1764dup (p.Arg589fs)	6389	SDHA	Pathogenic	2126633648	RCV001917391;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251552	251553	251552	-
NM_004168.4(SDHA):c.1764A>G (p.Ser588=)	6389	SDHA	Likely benign	2126633642	RCV001481633;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	251553	251553	251553	-
NM_004168.4(SDHA):c.1765C>T (p.Arg589Trp)	6389	SDHA	Pathogenic/Likely pathogenic	387906780	RCV000023042\|RCV000554026\|RCV000564186\|RCV001799611\|RCV003162258\|RCV003473121;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|	5	251554	251554	5:g.251554C>T	OMIM:600857.0005,ClinGen:CA342723,UniProtKB:P31040#VAR_065975	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1765C>A (p.Arg589=)	6389	SDHA	Likely benign	387906780	RCV001013029\|RCV001459383;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251554	251554	5:g.251554C>A	-
NM_004168.4(SDHA):c.1765C>G (p.Arg589Gly)	6389	SDHA	Likely pathogenic	387906780	RCV001234597;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251554	251554	5:g.251554C>G	-
NM_004168.4(SDHA):c.1766G>A (p.Arg589Gln)	6389	SDHA	Likely pathogenic	763766162	RCV000467377\|RCV001799664\|RCV002402299\|RCV003476121;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|Human Phenotype Ontology:HP:0100723,MONDO:MONDO:0011719,MeSH:D046152,MedGen:C0238198,OMIM:606764, Orphanet:44890\|MONDO:MONDO:0015	5	251555	251555	NC_000005.9:g.251555G>A	ClinGen:CA3173350	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1769del (p.Gly590fs)	6389	SDHA	Likely pathogenic	1554001958	RCV000530189;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	251555	251555	NC_000005.9:g.251558del	ClinGen:CA658657413	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1773_1774dup (p.His592fs)	6389	SDHA	Likely pathogenic	1561010948	RCV000691877;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251557	251558	5:g.251557_251558insGC	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1768G>A (p.Gly590Ser)	6389	SDHA	Uncertain significance	1736825032	RCV001317338;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251557	251557	251557	-
NM_004168.4(SDHA):c.1769G>A (p.Gly590Asp)	6389	SDHA	Uncertain significance	2126633698	RCV002009555;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251558	251558	251558	-
NM_004168.4(SDHA):c.1770C>T (p.Gly590=)	6389	SDHA	Likely benign	142457602	RCV000547065\|RCV002404528;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251559	251559	NC_000005.9:g.251559C>T	ClinGen:CA3173351	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1770C>A (p.Gly590=)	6389	SDHA	Likely benign	142457602	RCV002155760;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	251559	251559	251559	-
NM_004168.4(SDHA):c.1770C>G (p.Gly590=)	6389	SDHA	Likely benign	142457602	RCV002216389;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251559	251559	251559	-
NM_004168.4(SDHA):c.1771G>A (p.Ala591Thr)	6389	SDHA	Uncertain significance	1042170	RCV000460826\|RCV001013059\|RCV003441889\|RCV003476130;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642	5	251560	251560	NC_000005.9:g.251560G>A	ClinGen:CA3173352	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1772C>T (p.Ala591Val)	6389	SDHA	Uncertain significance	367621815	RCV000555083\|RCV001013062\|RCV002252166\|RCV003476309;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	251561	251561	5:g.251561C>T	ClinGen:CA112783592	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1773G>C (p.Ala591=)	6389	SDHA	Likely benign	555028212	RCV000463453\|RCV002402371;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251562	251562	NC_000005.9:g.251562G>C	ClinGen:CA3173355	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1773G>A (p.Ala591=)	6389	SDHA	Likely benign	555028212	RCV000530893\|RCV001013065;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251562	251562	5:g.251562G>A	ClinGen:CA3173354	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1773G>T (p.Ala591=)	6389	SDHA	Likely benign	-1	RCV002407674\|RCV003108090;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251562	251562		-
NM_004168.4(SDHA):c.1774C>A (p.His592Asn)	6389	SDHA	Uncertain significance	1579439269	RCV000801678\|RCV002397618;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251563	251563	5:g.251563C>A	-
NM_004168.4(SDHA):c.1774C>T (p.His592Tyr)	6389	SDHA	Uncertain significance	1579439269	RCV000820093;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251563	251563	5:g.251563C>T	-
NM_004168.4(SDHA):c.1775A>G (p.His592Arg)	6389	SDHA	Uncertain significance	1554001966	RCV000543362\|RCV002404529;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251564	251564	5:g.251564A>G	ClinGen:CA359000386	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1776T>C (p.His592=)	6389	SDHA	Benign/Likely benign	1126538	RCV000130494\|RCV000205292\|RCV000243217\|RCV000264789\|RCV000329216\|RCV000383884\|RCV003315895;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MedGen:CN169374\|MONDO:MONDO:0017366,MedGen:C1708353, Orphanet:29	5	251565	251565	5:g.251565T>C	ClinGen:CA345712	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1776T>G (p.His592Gln)	6389	SDHA	Uncertain significance	1126538	RCV000699883;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251565	251565	5:g.251565T>G	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1777G>A (p.Ala593Thr)	6389	SDHA	Uncertain significance	1736827311	RCV001213612;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251566	251566	5:g.251566G>A	-
NM_004168.4(SDHA):c.1778C>A (p.Ala593Asp)	6389	SDHA	Uncertain significance	1736827451	RCV001220797;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251567	251567	5:g.251567C>A	-
NM_004168.4(SDHA):c.1778C>T (p.Ala593Val)	6389	SDHA	Uncertain significance	1736827451	RCV001239207;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251567	251567	5:g.251567C>T	-
NM_004168.4(SDHA):c.1781G>A (p.Arg594Lys)	6389	SDHA	Conflicting interpretations of pathogenicity	1302547655	RCV000803949\|RCV001089548\|RCV003338812;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251570	251570	5:g.251570G>A	-
NM_004168.4(SDHA):c.1781G>T (p.Arg594Met)	6389	SDHA	Uncertain significance	-1	RCV002829535;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251570	251570	NC_000005.9:g.251570G>T	-
NM_004168.4(SDHA):c.1782G>A (p.Arg594=)	6389	SDHA	Likely benign	751329013	RCV000649465\|RCV002397293;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251571	251571	5:g.251571G>A	ClinGen:CA3173356	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1783G>A (p.Glu595Lys)	6389	SDHA	Uncertain significance	-1	RCV002999382;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251572	251572	NC_000005.9:g.251572G>A	-
NM_004168.4(SDHA):c.1786G>C (p.Asp596His)	6389	SDHA	Uncertain significance	371304688	RCV000570123\|RCV000805593;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251575	251575	NC_000005.9:g.251575G>C	ClinGen:CA359000449	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1786G>T (p.Asp596Tyr)	6389	SDHA	Uncertain significance	371304688	RCV001935549\|RCV002397912;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251575	251575	251575	-
NM_004168.4(SDHA):c.1787A>G (p.Asp596Gly)	6389	SDHA	Uncertain significance	1126557	RCV000560589\|RCV000562151\|RCV001755879\|RCV003409812;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900\|	5	251576	251576	5:g.251576A>G	ClinGen:CA3173359	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1789T>C (p.Tyr597His)	6389	SDHA	Uncertain significance	1060503721	RCV000469710\|RCV002411518;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251578	251578	NC_000005.9:g.251578T>C	ClinGen:CA16611990	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1790A>T (p.Tyr597Phe)	6389	SDHA	Uncertain significance	1736828708	RCV001202665;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251579	251579	5:g.251579A>T	-
NM_004168.4(SDHA):c.1790A>G (p.Tyr597Cys)	6389	SDHA	Uncertain significance	1736828708	RCV001926240\|RCV002397920;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251579	251579	251579	-
NM_004168.4(SDHA):c.1791C>T (p.Tyr597=)	6389	SDHA	Likely benign	1226155499	RCV002103020;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251580	251580	251580	-
NM_004168.4(SDHA):c.1792A>G (p.Lys598Glu)	6389	SDHA	Uncertain significance	2126633857	RCV001364671\|RCV002404866;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251581	251581	251581	-
NM_004168.4(SDHA):c.1793A>G (p.Lys598Arg)	6389	SDHA	Uncertain significance	1579439363	RCV000795043\|RCV002255522;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251582	251582	5:g.251582A>G	-
NM_004168.4(SDHA):c.1794G>A (p.Lys598=)	6389	SDHA	Uncertain significance	1554001975	RCV000536643;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	251583	251583	NC_000005.9:g.251583G>A	ClinGen:CA442657923	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1794+1G>A	6389	SDHA	Likely pathogenic	876659595	RCV000215067\|RCV001071130;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251584	251584	5:g.251584G>A	ClinGen:CA10578632	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1794+3G>C	6389	SDHA	Conflicting interpretations of pathogenicity	375883981	RCV000222853\|RCV000230640\|RCV001753651\|RCV003401134;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MedGen:C3661900\|	5	251586	251586	5:g.251586G>C	ClinGen:CA3173360	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1794+3G>A	6389	SDHA	Uncertain significance	375883981	RCV000649437\|RCV002406448;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	251586	251586	NC_000005.9:g.251586G>A	ClinGen:CA3173361	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1794+5G>C	6389	SDHA	Uncertain significance	1205244370	RCV001979288;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	251588	251588	251588	-
NM_004168.4(SDHA):c.1794+5G>A	6389	SDHA	Uncertain significance	-1	RCV002407780\|RCV003097247;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251588	251588	251588	-
NM_004168.4(SDHA):c.1794+6C>T	6389	SDHA	Likely benign	-1	RCV002825362;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251589	251589	NC_000005.9:g.251589C>T	-
NM_004168.4(SDHA):c.1794+8T>A	6389	SDHA	Likely benign	1050394308	RCV000460313;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251591	251591	NC_000005.9:g.251591T>A	ClinGen:CA16611847	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1794+8T>G	6389	SDHA	Likely benign	1050394308	RCV000649471;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251591	251591	5:g.251591T>G	ClinGen:CA658796493	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1794+10C>T	6389	SDHA	Likely benign	1060505010	RCV000456309;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251593	251593	NC_000005.9:g.251593C>T	ClinGen:CA16611901	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1794+11T>C	6389	SDHA	Likely benign	-1	RCV002740344;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251594	251594	NC_000005.9:g.251594T>C	-
NM_004168.4(SDHA):c.1794+14C>G	6389	SDHA	Likely benign	1412436993	RCV002129016;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251597	251597	251597	-
NM_004168.4(SDHA):c.1794+15C>T	6389	SDHA	Likely benign	-1	RCV003089613;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251598	251598	NC_000005.9:g.251598C>T	-
NM_004168.4(SDHA):c.1794+17C>T	6389	SDHA	Likely benign	747352875	RCV002082675;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	251600	251600	251600	-
NM_004168.4(SDHA):c.1794+18G>A	6389	SDHA	Likely benign	768882490	RCV002182070;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251601	251601	251601	-
NM_004168.4(SDHA):c.1794+18G>T	6389	SDHA	Likely benign	-1	RCV003032689;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251601	251601	NC_000005.9:g.251601G>T	-
NM_004168.4(SDHA):c.1794+19C>A	6389	SDHA	Likely benign	776409305	RCV002098359;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251602	251602	251602	-
NM_004168.4(SDHA):c.1794+20C>A	6389	SDHA	Likely benign	2126633960	RCV002165965;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	251603	251603	251603	-
NM_004168.4(SDHA):c.1795-66C>T	6389	SDHA	Benign	387134	RCV001544167\|RCV001544166\|RCV001544302;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154\|MONDO:MONDO:0031006,MedGen:C5543254,OMIM:619259	5	254442	254442	254442	-
NM_004168.4(SDHA):c.1795-6C>A	6389	SDHA	Uncertain significance	756792828	RCV001036595;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	254502	254502	5:g.254502C>A	-
NM_004168.4(SDHA):c.1795-5C>T	6389	SDHA	Conflicting interpretations of pathogenicity	1169912956	RCV000998349\|RCV001415584;	N	MedGen:C3661900\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	254503	254503	5:g.254503C>T	-
NM_004168.4(SDHA):c.1795-3C>G	6389	SDHA	Conflicting interpretations of pathogenicity	544544409	RCV000998350\|RCV001056823\|RCV001013116;	N	MedGen:C3661900\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	254505	254505	5:g.254505C>G	-
NM_004168.4(SDHA):c.1795-1G>T	6389	SDHA	Pathogenic/Likely pathogenic	778516878	RCV000853252\|RCV001013115\|RCV001379066;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	254507	254507	5:g.254507G>T	-
NM_004168.4(SDHA):c.1797G>A (p.Val599=)	6389	SDHA	Likely benign	1060505012	RCV001506605;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	254510	254510	NC_000005.9:g.254510G>A	ClinGen:CA16611902	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1798C>T (p.Arg600Trp)	6389	SDHA	Uncertain significance	878854630	RCV000233512\|RCV002411041\|RCV002500782\|RCV002510828;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154; MO	5	254511	254511	5:g.254511C>T	ClinGen:CA10582432	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1799G>A (p.Arg600Gln)	6389	SDHA	Conflicting interpretations of pathogenicity	1126568	RCV000246566\|RCV000568295\|RCV001245529\|RCV001528683\|RCV001799648\|RCV003447520\|RCV003475856;	N	MedGen:CN169374\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MedGen:C3661900\|Human Phenotype Ontology:HP:010	5	254512	254512	NC_000005.9:g.254512G>A	ClinGen:CA3173431	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1804G>A (p.Asp602Asn)	6389	SDHA	Uncertain significance	1737043619	RCV001306645\|RCV003166745;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	254517	254517	254517	-
NM_004168.4(SDHA):c.1806T>C (p.Asp602=)	6389	SDHA	Likely benign	1554002427	RCV000543136\|RCV002413605;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	254519	254519	NC_000005.9:g.254519T>C	ClinGen:CA359001660	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1808A>G (p.Glu603Gly)	6389	SDHA	Uncertain significance	1737044250	RCV001347354;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	254521	254521	254521	-
NM_004168.4(SDHA):c.1811A>G (p.Tyr604Cys)	6389	SDHA	Uncertain significance	1737044552	RCV001215822;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	254524	254524	5:g.254524A>G	-
NM_004168.4(SDHA):c.1812C>T (p.Tyr604=)	6389	SDHA	Likely benign	1436919553	RCV000649469\|RCV002406451\|RCV002477442;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	5	254525	254525	5:g.254525C>T	ClinGen:CA359001700	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1813G>A (p.Asp605Asn)	6389	SDHA	Uncertain significance	771593214	RCV000649401\|RCV002406446;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	254526	254526	5:g.254526G>A	ClinGen:CA3173432	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1813G>C (p.Asp605His)	6389	SDHA	Uncertain significance	771593214	RCV000649442\|RCV002406449;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	254526	254526	5:g.254526G>C	ClinGen:CA359001707	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1816T>A (p.Tyr606Asn)	6389	SDHA	Uncertain significance	17400614	RCV001996416;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	254529	254529	254529	-
NM_004168.4(SDHA):c.1818C>T (p.Tyr606=)	6389	SDHA	Likely benign	1226342299	RCV001474951\|RCV002414142;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	254531	254531	254531	-
NM_004168.4(SDHA):c.1819T>C (p.Ser607Pro)	6389	SDHA	Uncertain significance	1183122120	RCV001220657\|RCV002411815;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	254532	254532	5:g.254532T>C	-
NM_004168.4(SDHA):c.1825C>T (p.Pro609Ser)	6389	SDHA	Uncertain significance	1737046014	RCV001235732;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	254538	254538	5:g.254538C>T	-
NM_004168.4(SDHA):c.1826C>G (p.Pro609Arg)	6389	SDHA	Uncertain significance	2126641323	RCV001359503;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	254539	254539	254539	-
NM_004168.4(SDHA):c.1827C>A (p.Pro609=)	6389	SDHA	Likely benign	1060505006	RCV000474438\|RCV002255414;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	254540	254540	NC_000005.9:g.254540C>A	ClinGen:CA16611904	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1827C>T (p.Pro609=)	6389	SDHA	Likely benign	1060505006	RCV001398250;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	254540	254540	254540	-
NM_004168.4(SDHA):c.1828A>G (p.Ile610Val)	6389	SDHA	Uncertain significance	1554002446	RCV000649412\|RCV002406447;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	254541	254541	5:g.254541A>G	ClinGen:CA359001814	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1830C>G (p.Ile610Met)	6389	SDHA	Uncertain significance	1209697697	RCV000802672\|RCV002406780;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	254543	254543	5:g.254543C>G	-
NM_004168.4(SDHA):c.1832A>G (p.Gln611Arg)	6389	SDHA	Uncertain significance	1737046877	RCV001348869;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	254545	254545	254545	-
NM_004168.4(SDHA):c.1834G>A (p.Gly612Arg)	6389	SDHA	Uncertain significance	1737047578	RCV001327512;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	254547	254547	254547	-
NM_004168.4(SDHA):c.1835G>A (p.Gly612Glu)	6389	SDHA	Uncertain significance	1057523336	RCV000424508\|RCV000696172\|RCV001013331\|RCV003409604;	N	MedGen:C3661900\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|	5	254548	254548	5:g.254548G>A	ClinGen:CA16605350	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1843AAG[1] (p.Lys616del)	6389	SDHA	Uncertain significance	1737048556	RCV001236554;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	254554	254556	5:g.254554_254556del	-
NM_004168.4(SDHA):c.1842G>A (p.Gln614=)	6389	SDHA	Likely benign	2126641413	RCV001398650;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	254555	254555	254555	-
NM_004168.4(SDHA):c.1845G>A (p.Lys615=)	6389	SDHA	Likely benign	1442827207	RCV001399841\|RCV003355456;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	254558	254558	254558	-
NM_004168.4(SDHA):c.1846A>G (p.Lys616Glu)	6389	SDHA	Uncertain significance	1453752069	RCV001051757;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	254559	254559	5:g.254559A>G	-
NM_004168.4(SDHA):c.1846A>T (p.Lys616Ter)	6389	SDHA	Pathogenic	-1	RCV002877619;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	254559	254559	NC_000005.9:g.254559A>T	-
NM_004168.4(SDHA):c.1849C>T (p.Pro617Ser)	6389	SDHA	Uncertain significance	1199988395	RCV000560099\|RCV003352923;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	254562	254562	NC_000005.9:g.254562C>T	ClinGen:CA359001942	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1850C>T (p.Pro617Leu)	6389	SDHA	Uncertain significance	1485754812	RCV001343849;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	254563	254563	254563	-
NM_004168.4(SDHA):c.1857G>A (p.Glu619=)	6389	SDHA	Likely benign	1247081812	RCV000536406\|RCV002413606;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	254570	254570	5:g.254570G>A	ClinGen:CA359001980	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1860G>A (p.Glu620=)	6389	SDHA	Likely benign	1447230295	RCV001409858\|RCV002413973;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	254573	254573	254573	-
NM_004168.4(SDHA):c.1861C>G (p.His621Asp)	6389	SDHA	Uncertain significance	1554002475	RCV000799620;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	254574	254574	5:g.254574C>G	-
NM_004168.4(SDHA):c.1862A>G (p.His621Arg)	6389	SDHA	Uncertain significance	1737050290	RCV001326946\|RCV003346472;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	254575	254575	254575	-
NM_004168.4(SDHA):c.1863C>G (p.His621Gln)	6389	SDHA	Uncertain significance	1554002478	RCV000548911\|RCV002413607\|RCV003476310;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	254576	254576	5:g.254576C>G	ClinGen:CA359001997	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1866G>A (p.Trp622Ter)	6389	SDHA	Conflicting interpretations of pathogenicity	1579445179	RCV000813142\|RCV001523817\|RCV002462179;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MedGen:CN517202	5	254579	254579	5:g.254579G>A	-
NM_004168.4(SDHA):c.1871A>G (p.Lys624Arg)	6389	SDHA	Uncertain significance	1579445190	RCV000794154;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	254584	254584	5:g.254584A>G	-
NM_004168.4(SDHA):c.1873C>T (p.His625Tyr)	6389	SDHA	Uncertain significance	1554002483	RCV000524624;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	254586	254586	5:g.254586C>T	ClinGen:CA359002059	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1875C>T (p.His625=)	6389	SDHA	Likely benign	1579445214	RCV001013495\|RCV001451921;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	254588	254588	5:g.254588C>T	-
NM_004168.4(SDHA):c.1878C>T (p.Thr626=)	6389	SDHA	Likely benign	1579445226	RCV001472426;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	254591	254591	5:g.254591C>T	-
NM_004168.4(SDHA):c.1880dup (p.Ser628fs)	6389	SDHA	Uncertain significance	1579445237	RCV000801184;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	254592	254593	5:g.254592_254593insT	-
NM_004168.4(SDHA):c.1879C>T (p.Leu627=)	6389	SDHA	Likely benign	1169965410	RCV001460711;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	254592	254592	254592	-
NM_004168.4(SDHA):c.1880T>G (p.Leu627Arg)	6389	SDHA	Uncertain significance	1737051659	RCV001343344\|RCV003365348;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	254593	254593	254593	-
NM_004168.4(SDHA):c.1881G>C (p.Leu627=)	6389	SDHA	Likely benign	1390181757	RCV002075064\|RCV002407392;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	254594	254594	254594	-
NM_004168.4(SDHA):c.1885dup (p.Tyr629fs)	6389	SDHA	Conflicting interpretations of pathogenicity	750865703	RCV000537063\|RCV001013539\|RCV001555544\|RCV003451192\|RCV003476311;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165	5	254597	254598	NC_000005.9:g.254598dup	ClinGen:CA3173435	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1884C>G (p.Ser628=)	6389	SDHA	Likely benign	1224468457	RCV001213221\|RCV002411786;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	254597	254597	5:g.254597C>G	-
NM_004168.4(SDHA):c.1884C>T (p.Ser628=)	6389	SDHA	Likely benign	1224468457	RCV002133046;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	254597	254597	254597	-
NM_004168.4(SDHA):c.1885T>A (p.Tyr629Asn)	6389	SDHA	Uncertain significance	1579445293	RCV000819886;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	254598	254598	5:g.254598T>A	-
NM_004168.4(SDHA):c.1886A>T (p.Tyr629Phe)	6389	SDHA	Benign/Likely benign	6960	RCV000210491\|RCV000325852\|RCV000243534\|RCV000270762\|RCV000389777\|RCV000492773\|RCV001658006\|RCV003316164;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0017366,MedGen:C1708353, Orphanet:29072\|MedGen:CN169374\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	254599	254599	NC_000005.9:g.254599A>T	ClinGen:CA358567,UniProtKB:P31040#VAR_071037	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1886A>C (p.Tyr629Ser)	6389	SDHA	Uncertain significance	6960	RCV000649426;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	254599	254599	5:g.254599A>C	ClinGen:CA359002158	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1886A>G (p.Tyr629Cys)	6389	SDHA	Uncertain significance	6960	RCV001013540\|RCV001052870\|RCV003473570\|RCV003159171;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154\|Me	5	254599	254599	5:g.254599A>G	-
NM_004168.4(SDHA):c.1889T>C (p.Val630Ala)	6389	SDHA	Uncertain significance	1392791825	RCV000705910\|RCV002406647;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	254602	254602	NC_000005.9:g.254602T>C	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1890G>C (p.Val630=)	6389	SDHA	Likely benign	1405784467	RCV001013473\|RCV001410466;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	254603	254603	5:g.254603G>C	-
NM_004168.4(SDHA):c.1890G>A (p.Val630=)	6389	SDHA	Uncertain significance	1405784467	RCV002004245;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	254603	254603	254603	-
NM_004168.4(SDHA):c.1891G>A (p.Asp631Asn)	6389	SDHA	Uncertain significance	776500078	RCV001245717;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	254604	254604	5:g.254604G>A	-
NM_004168.4(SDHA):c.1893C>T (p.Asp631=)	6389	SDHA	Likely benign	1364764796	RCV000649482\|RCV002406452;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	254606	254606	NC_000005.9:g.254606C>T	ClinGen:CA359002213	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1893C>A (p.Asp631Glu)	6389	SDHA	Uncertain significance	1364764796	RCV001297559;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	254606	254606	254606	-
NM_004168.4(SDHA):c.1894G>A (p.Val632Ile)	6389	SDHA	Conflicting interpretations of pathogenicity	369639811	RCV000525826\|RCV001013519;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	254607	254607	5:g.254607G>A	ClinGen:CA3173439	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1894G>T (p.Val632Phe)	6389	SDHA	Conflicting interpretations of pathogenicity	369639811	RCV000575685\|RCV000539102\|RCV003313101;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MedGen:C3661900	5	254607	254607	NC_000005.9:g.254607G>T	ClinGen:CA3173438	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1895T>C (p.Val632Ala)	6389	SDHA	Uncertain significance	774609159	RCV000821481\|RCV002408982;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	254608	254608	5:g.254608T>C	-
NM_004168.4(SDHA):c.1896T>C (p.Val632=)	6389	SDHA	Conflicting interpretations of pathogenicity	1554002492	RCV002104278\|RCV002480982\|RCV002409556;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	254609	254609	254609	-
NM_004168.4(SDHA):c.1897G>A (p.Gly633Ser)	6389	SDHA	Conflicting interpretations of pathogenicity	2126641674	RCV001366404\|RCV002413875;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	254610	254610	254610	-
NM_004168.4(SDHA):c.1900A>G (p.Thr634Ala)	6389	SDHA	Uncertain significance	1017441235	RCV000465027\|RCV002411519;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	254613	254613	NC_000005.9:g.254613A>G	ClinGen:CA16612060	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1900A>T (p.Thr634Ser)	6389	SDHA	Uncertain significance	1017441235	RCV001064925;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	254613	254613	5:g.254613A>T	-
NM_004168.4(SDHA):c.1902T>G (p.Thr634=)	6389	SDHA	Likely benign	2126641691	RCV001475201;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	254615	254615	254615	-
NM_004168.4(SDHA):c.1903G>A (p.Gly635Arg)	6389	SDHA	Uncertain significance	1737055056	RCV001344337;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	254616	254616	254616	-
NM_004168.4(SDHA):c.1908G>T (p.Lys636Asn)	6389	SDHA	Uncertain significance	1244151760	RCV001326893\|RCV002412048;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	254621	254621	254621	-
NM_004168.4(SDHA):c.1908+2T>C	6389	SDHA	Uncertain significance	1737056056	RCV001306427;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	254623	254623	254623	-
NM_004168.4(SDHA):c.1908+5G>C	6389	SDHA	Uncertain significance	759574062	RCV001987657;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	254626	254626	254626	-
NM_004168.4(SDHA):c.1908+6T>C	6389	SDHA	Uncertain significance	1359050908	RCV000527847\|RCV003476312;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	254627	254627	NC_000005.9:g.254627T>C	ClinGen:CA557103331	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1908+8T>G	6389	SDHA	Likely benign	2126641731	RCV001457829;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	254629	254629	254629	-
NM_004168.4(SDHA):c.1908+9G>A	6389	SDHA	Likely benign	767578208	RCV000540014;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	254630	254630	NC_000005.9:g.254630G>A	ClinGen:CA3173442	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1908+10G>A	6389	SDHA	Likely benign	1579445450	RCV001432294;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	254631	254631	5:g.254631G>A	-
NM_004168.4(SDHA):c.1908+15C>T	6389	SDHA	Benign/Likely benign	34504623	RCV000249299\|RCV000294605\|RCV000349503\|RCV000385355\|RCV001812726\|RCV003316404\|RCV002411119;	N	MedGen:CN169374\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0017366,MedGen:C1708353, Orphanet:29072\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506\|MedGen:C3661900\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165	5	254636	254636	NC_000005.9:g.254636C>T	ClinGen:CA3173444	C0023264 256000 Leigh syndrome;
NM_004168.4(SDHA):c.1908+85G>A	6389	SDHA	Benign	6864807	RCV000987496;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	254706	254706	5:g.254706G>A	-
NM_004168.4(SDHA):c.1908+90A>G	6389	SDHA	Benign	6888536	RCV000987497;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	254711	254711	5:g.254711A>G	-
NM_004168.4(SDHA):c.1909-20C>A	6389	SDHA	Likely benign	1737178548	RCV002176336;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	256429	256429	256429	-
NM_004168.4(SDHA):c.1909-16_1909-13del	6389	SDHA	Likely benign	2126645630	RCV002076539;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	256430	256433	256429	-
NM_004168.4(SDHA):c.1909-18C>T	6389	SDHA	Likely benign	781153748	RCV002182871;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	256431	256431	256431	-
NM_004168.4(SDHA):c.1909-16G>A	6389	SDHA	Likely benign	-1	RCV002857604;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	256433	256433	NC_000005.9:g.256433G>A	-
NM_004168.4(SDHA):c.1909-15A>C	6389	SDHA	Likely benign	1189118840	RCV002187315;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	256434	256434	256434	-
NM_004168.4(SDHA):c.1909-15A>G	6389	SDHA	Likely benign	-1	RCV003085917;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	256434	256434	NC_000005.9:g.256434A>G	-
NM_004168.4(SDHA):c.1909-12_1909-11del	6389	SDHA	Conflicting interpretations of pathogenicity	372662724	RCV000281629\|RCV000337728\|RCV000394391\|RCV000483037\|RCV000492532\|RCV001354980\|RCV002061279;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506\|Human Phenotype Ontology:HP:0002666,MONDO:MONDO:0008233,MedGen:C0031511,OMIM:171300, Orphanet:29072\|MedGen:CN169374\|MONDO:MONDO:001	5	256435	256436	NC_000005.9:g.256435CT[1]	ClinGen:CA3173456	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1909-9_1909-7del	6389	SDHA	Likely benign	-1	RCV002632732;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	256436	256438	NC_000005.9:g.256437CTT[1]	-
NM_004168.4(SDHA):c.1909-8_1909-4del	6389	SDHA	Uncertain significance	1737179400	RCV001238891;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	256438	256442	5:g.256438_256442del	-
NM_004168.4(SDHA):c.1909-11T>G	6389	SDHA	Likely benign	2126645679	RCV002177144;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	256438	256438	256438	-
NM_004168.4(SDHA):c.1909-9C>T	6389	SDHA	Likely benign	2126645687	RCV001443345;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	256440	256440	256440	-
NM_004168.4(SDHA):c.1909-9C>G	6389	SDHA	Likely benign	-1	RCV002584357;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	256440	256440	NC_000005.9:g.256440C>G	-
NM_004168.4(SDHA):c.1909-6T>C	6389	SDHA	Likely benign	-1	RCV002857334;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	256443	256443	NC_000005.9:g.256443T>C	-
NM_004168.4(SDHA):c.1909-5T>C	6389	SDHA	Conflicting interpretations of pathogenicity	1197849830	RCV001067730\|RCV002411598;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	256444	256444	5:g.256444T>C	-
NM_004168.4(SDHA):c.1909-5T>G	6389	SDHA	Uncertain significance	1197849830	RCV002042725;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	256444	256444	256444	-
NM_004168.4(SDHA):c.1909-3A>G	6389	SDHA	Uncertain significance	-1	RCV002408408\|RCV003100928;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	256446	256446	256446	-
NM_004168.4(SDHA):c.1909-2A>G	6389	SDHA	Conflicting interpretations of pathogenicity	747939816	RCV000565006\|RCV000692849;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	256447	256447	5:g.256447A>G	ClinGen:CA3173457	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1909-1G>A	6389	SDHA	Conflicting interpretations of pathogenicity	1159597886	RCV000574361\|RCV001203781;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	256448	256448	5:g.256448G>A	ClinGen:CA359002550	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1909G>A (p.Val637Ile)	6389	SDHA	Uncertain significance	769599373	RCV000792459\|RCV003166093;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	256449	256449	5:g.256449G>A	-
NM_004168.4(SDHA):c.1910T>C (p.Val637Ala)	6389	SDHA	Uncertain significance	1737179959	RCV001346382\|RCV002412089;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	256450	256450	256450	-
NM_004168.4(SDHA):c.1911C>T (p.Val637=)	6389	SDHA	Benign/Likely benign	11557098	RCV000210496\|RCV000343504\|RCV000298002\|RCV000402055\|RCV000426571\|RCV000564874\|RCV001579978\|RCV003316167;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506\|MONDO:MONDO:0017366,MedGen:C1708353, Orphanet:29072\|MONDO:MONDO:0100	5	256451	256451	NC_000005.9:g.256451C>T	ClinGen:CA358569	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1913del (p.Thr638fs)	6389	SDHA	Uncertain significance	1554002857	RCV000649411;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	256453	256453	NC_000005.9:g.256453del	ClinGen:CA658796494	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1913C>T (p.Thr638Ile)	6389	SDHA	Uncertain significance	370133236	RCV000812350\|RCV001013675;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	256453	256453	5:g.256453C>T	-
NM_004168.4(SDHA):c.1913C>G (p.Thr638Ser)	6389	SDHA	Uncertain significance	370133236	RCV002042621;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	256453	256453	256453	-
NM_004168.4(SDHA):c.1914T>C (p.Thr638=)	6389	SDHA	Likely benign	2126645757	RCV001476197\|RCV002414151;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	256454	256454	256454	-
NM_004168.4(SDHA):c.1915C>G (p.Leu639Val)	6389	SDHA	Uncertain significance	1126697	RCV000552499\|RCV000563708\|RCV002509436;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	5	256455	256455	NC_000005.9:g.256455C>G	ClinGen:CA3173460	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1919A>G (p.Glu640Gly)	6389	SDHA	Conflicting interpretations of pathogenicity	372480044	RCV000239361\|RCV000574591\|RCV000663177\|RCV000765835\|RCV000836807;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|	5	256459	256459	NC_000005.9:g.256459A>G	ClinGen:CA3173461	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1920A>G (p.Glu640=)	6389	SDHA	Likely benign	2126645771	RCV001407237\|RCV002413965;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	256460	256460	256460	-
NM_004168.4(SDHA):c.1922A>G (p.Tyr641Cys)	6389	SDHA	Uncertain significance	-1	RCV003092637;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	256462	256462	NC_000005.9:g.256462A>G	-
NM_004168.4(SDHA):c.1923T>C (p.Tyr641=)	6389	SDHA	Likely benign	1444319863	RCV000533337\|RCV000571470;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	256463	256463	NC_000005.9:g.256463T>C	ClinGen:CA359002659	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1926A>G (p.Arg642=)	6389	SDHA	Likely benign	1554002873	RCV000545820\|RCV002413609;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	256466	256466	NC_000005.9:g.256466A>G	ClinGen:CA359002684	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1927C>T (p.Pro643Ser)	6389	SDHA	Uncertain significance	1579448568	RCV000817037\|RCV002406866;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	256467	256467	5:g.256467C>T	-
NM_004168.4(SDHA):c.1927C>A (p.Pro643Thr)	6389	SDHA	Uncertain significance	1579448568	RCV001229948\|RCV002411846;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	256467	256467	5:g.256467C>A	-
NM_004168.4(SDHA):c.1928C>G (p.Pro643Arg)	6389	SDHA	Uncertain significance	1060503717	RCV000459590\|RCV002475894\|RCV003168871;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0031006,MedGen:C5543254,OMIM:619259; MONDO:MONDO:01002	5	256468	256468	NC_000005.9:g.256468C>G	ClinGen:CA16612063	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1929C>T (p.Pro643=)	6389	SDHA	Likely benign	761201589	RCV000552289\|RCV000562383;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	256469	256469	NC_000005.9:g.256469C>T	ClinGen:CA3173462	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1930G>A (p.Val644Met)	6389	SDHA	Uncertain significance	3211483	RCV000475448\|RCV000662992\|RCV002251478\|RCV002411517\|RCV003401494\|RCV003476126;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672,	5	256470	256470	NC_000005.9:g.256470G>A	ClinGen:CA3173463	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1931T>G (p.Val644Gly)	6389	SDHA	Uncertain significance	-1	RCV002706539;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	256471	256471	NC_000005.9:g.256471T>G	-
NM_004168.4(SDHA):c.1932G>A (p.Val644=)	6389	SDHA	Benign	6961	RCV000118316\|RCV000162483\|RCV000273207\|RCV000303618\|RCV000358445\|RCV001513599\|RCV001705859\|RCV003315680;	N	MedGen:CN169374\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506\|MONDO:MONDO:0017366,MedGen:C1708353, Orphanet:29072\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:320	5	256472	256472	5:g.256472G>A	ClinGen:CA155150	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1934T>C (p.Ile645Thr)	6389	SDHA	Uncertain significance	1282623859	RCV000685210\|RCV002406529\|RCV003472184;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154	5	256474	256474	5:g.256474T>C	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1935C>T (p.Ile645=)	6389	SDHA	Likely benign	762128553	RCV000532848\|RCV001013766;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	256475	256475	NC_000005.9:g.256475C>T	ClinGen:CA3173464	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1935C>G (p.Ile645Met)	6389	SDHA	Uncertain significance	762128553	RCV000693481\|RCV002406585;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	256475	256475	5:g.256475C>G	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1935C>A (p.Ile645=)	6389	SDHA	Likely benign	762128553	RCV001461792\|RCV002414111;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	256475	256475	256475	-
NM_004168.4(SDHA):c.1936G>A (p.Asp646Asn)	6389	SDHA	Uncertain significance	376986935	RCV000686417\|RCV002254942\|RCV002406538;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	256476	256476	NC_000005.9:g.256476G>A	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1940A>G (p.Lys647Arg)	6389	SDHA	Uncertain significance	1737186768	RCV001232477;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	256480	256480	5:g.256480A>G	-
NM_004168.4(SDHA):c.1942A>C (p.Thr648Pro)	6389	SDHA	Uncertain significance	758054627	RCV000460218\|RCV000570413;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	256482	256482	NC_000005.9:g.256482A>C	ClinGen:CA3173467	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1943C>G (p.Thr648Ser)	6389	SDHA	Uncertain significance	1420345359	RCV000545606\|RCV002413610;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	256483	256483	NC_000005.9:g.256483C>G	ClinGen:CA359002836	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1943del (p.Thr648fs)	6389	SDHA	Uncertain significance	2126645882	RCV001961342;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	256483	256483	256482	-
NM_004168.4(SDHA):c.1945_1946del (p.Leu649fs)	6389	SDHA	Uncertain significance	112307877	RCV001197787\|RCV001528748\|RCV003339530;	N	MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506\|MedGen:CN517202\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	256484	256485	5:g.256484_256485del	-
NM_004168.4(SDHA):c.1945T>G (p.Leu649Val)	6389	SDHA	Uncertain significance	1737187966	RCV001351552\|RCV002413833;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	256485	256485	256485	-
NM_004168.4(SDHA):c.1946T>G (p.Leu649Trp)	6389	SDHA	Uncertain significance	899598021	RCV001366168\|RCV003284274;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	256486	256486	256486	-
NM_004168.4(SDHA):c.1949A>G (p.Asn650Ser)	6389	SDHA	Uncertain significance	1485747007	RCV000794100\|RCV002406734\|RCV002487656;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; M	5	256489	256489	5:g.256489A>G	-
NM_004168.4(SDHA):c.1950C>T (p.Asn650=)	6389	SDHA	Likely benign	1042430	RCV000473028\|RCV001013725;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	256490	256490	NC_000005.9:g.256490C>T	ClinGen:CA3173469	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1951G>A (p.Glu651Lys)	6389	SDHA	Uncertain significance	375396913	RCV000204436\|RCV001013731\|RCV003441788\|RCV003474987;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642	5	256491	256491	NC_000005.9:g.256491G>A	ClinGen:CA348665	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1951G>C (p.Glu651Gln)	6389	SDHA	Uncertain significance	375396913	RCV000662705\|RCV000793459\|RCV002422447;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	256491	256491	NC_000005.9:g.256491G>C	-	C3279992 614165 Paragangliomas 5;
NM_004168.4(SDHA):c.1951del (p.Glu651fs)	6389	SDHA	Uncertain significance	1561016316	RCV000698069;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	256491	256491	NC_000005.9:g.256491del	-	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1952A>G (p.Glu651Gly)	6389	SDHA	Uncertain significance	1737189246	RCV001246366;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	256492	256492	5:g.256492A>G	-
NM_004168.4(SDHA):c.1953G>A (p.Glu651=)	6389	SDHA	Likely benign	1579448683	RCV001013825\|RCV002068877;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	256493	256493	5:g.256493G>A	-
NM_004168.4(SDHA):c.1953G>T (p.Glu651Asp)	6389	SDHA	Uncertain significance	1579448683	RCV002027753\|RCV002423281;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	256493	256493	256493	-
NM_004168.4(SDHA):c.1954G>A (p.Ala652Thr)	6389	SDHA	Uncertain significance	1737189728	RCV001040638;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	256494	256494	5:g.256494G>A	-
NM_004168.4(SDHA):c.1955C>T (p.Ala652Val)	6389	SDHA	Uncertain significance	1554002888	RCV000566977\|RCV000688050;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	256495	256495	5:g.256495C>T	ClinGen:CA359002953	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1958A>T (p.Asp653Val)	6389	SDHA	Uncertain significance	1737190360	RCV001227009;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	256498	256498	5:g.256498A>T	-
NM_004168.4(SDHA):c.1958A>C (p.Asp653Ala)	6389	SDHA	Uncertain significance	1737190360	RCV001366085;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	256498	256498	256498	-
NM_004168.4(SDHA):c.1959C>T (p.Asp653=)	6389	SDHA	Likely benign	-1	RCV002421678\|RCV003097389;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	256499	256499		-
NM_004168.4(SDHA):c.1960T>G (p.Cys654Gly)	6389	SDHA	Uncertain significance	60587941	RCV000649402\|RCV003162970;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	256500	256500	5:g.256500T>G	ClinGen:CA112784567	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1962_1963del (p.Ala655fs)	6389	SDHA	Uncertain significance	2126645995	RCV001965962;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	256500	256501	256499	-
NM_004168.4(SDHA):c.1960T>A (p.Cys654Ser)	6389	SDHA	Uncertain significance	-1	RCV002421741\|RCV003097391;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	256500	256500	256500	-
NM_004168.4(SDHA):c.1961G>C (p.Cys654Ser)	6389	SDHA	Uncertain significance	1554002895	RCV000649429\|RCV001013863;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	256501	256501	5:g.256501G>C	ClinGen:CA359003005	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1963G>C (p.Ala655Pro)	6389	SDHA	Uncertain significance	-1	RCV002913898;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	256503	256503	NC_000005.9:g.256503G>C	-
NM_004168.4(SDHA):c.1968C>T (p.Thr656=)	6389	SDHA	Likely benign	3211499	RCV000557985\|RCV003431100\|RCV002256389;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	256508	256508	5:g.256508C>T	ClinGen:CA3173472	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1969G>A (p.Val657Ile)	6389	SDHA	Benign	6962	RCV000118317\|RCV000162484\|RCV000269248\|RCV000309260\|RCV000363917\|RCV001513600\|RCV001705860\|RCV003315681;	N	MedGen:CN169374\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506\|MONDO:MONDO:0017366,MedGen:C1708353, Orphanet:2907	5	256509	256509	5:g.256509G>A	ClinGen:CA155152,UniProtKB:P31040#VAR_049217	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1969G>C (p.Val657Leu)	6389	SDHA	Uncertain significance	6962	RCV001153726\|RCV001156338\|RCV001156339;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506\|MONDO:MONDO:0017366,MedGen:C1708353, Orphanet:29072	5	256509	256509	5:g.256509G>C	-
NM_004168.4(SDHA):c.1971C>T (p.Val657=)	6389	SDHA	Likely benign	746083858	RCV000463658\|RCV000573225\|RCV000615882;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN169374	5	256511	256511	NC_000005.9:g.256511C>T	ClinGen:CA3173474	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1972C>A (p.Pro658Thr)	6389	SDHA	Uncertain significance	2126646066	RCV001975339;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	256512	256512	256512	-
NM_004168.4(SDHA):c.1973C>T (p.Pro658Leu)	6389	SDHA	Conflicting interpretations of pathogenicity	377632619	RCV000217918\|RCV000275247\|RCV000333745\|RCV000388419\|RCV000649461\|RCV000765836\|RCV001775682\|RCV001818525;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0017366,MedGen:C1708353, Orphanet:29072\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506\|MONDO:MONDO:01	5	256513	256513	5:g.256513C>T	ClinGen:CA3173475	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1974G>C (p.Pro658=)	6389	SDHA	Benign/Likely benign	1042446	RCV000239372\|RCV000427231\|RCV000568815\|RCV001156341\|RCV001156342\|RCV001156340\|RCV001722281;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MedGen:CN169374\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011	5	256514	256514	NC_000005.9:g.256514G>C	ClinGen:CA3173476	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1974G>A (p.Pro658=)	6389	SDHA	Likely benign	1042446	RCV000565278\|RCV000827097\|RCV001080610;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	256514	256514	NC_000005.9:g.256514G>A	ClinGen:CA3173477	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1974G>T (p.Pro658=)	6389	SDHA	Likely benign	1042446	RCV001489218\|RCV002416227;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	256514	256514	5:g.256514G>T	-
NM_004168.4(SDHA):c.1977A>G (p.Pro659=)	6389	SDHA	Conflicting interpretations of pathogenicity	768693502	RCV001013815\|RCV000887554\|RCV001158014\|RCV001158015\|RCV001158016;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0017366,MedGen:C1708353, Orphanet:29072\|MONDO:MONDO:	5	256517	256517	5:g.256517A>G	-
NM_004168.4(SDHA):c.1978G>A (p.Ala660Thr)	6389	SDHA	Uncertain significance	1554002911	RCV000649433\|RCV002422381;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	256518	256518	5:g.256518G>A	ClinGen:CA359003135	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1979C>G (p.Ala660Gly)	6389	SDHA	Conflicting interpretations of pathogenicity	191412461	RCV000227636\|RCV000409751\|RCV000563763\|RCV000998351\|RCV001158018\|RCV001158017\|RCV001158019\|RCV003401176;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|	5	256519	256519	5:g.256519C>G	ClinGen:CA3173479	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1979C>T (p.Ala660Val)	6389	SDHA	Uncertain significance	191412461	RCV000813379;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	256519	256519	5:g.256519C>T	-
NM_004168.4(SDHA):c.1984C>T (p.Arg662Cys)	6389	SDHA	Conflicting interpretations of pathogenicity	1737195067	RCV001078147\|RCV001224277\|RCV001759641\|RCV002415972;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672,O	5	256524	256524	5:g.256524C>T	-
NM_004168.4(SDHA):c.1986C>G (p.Arg662=)	6389	SDHA	Likely benign	762372686	RCV001492306;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	256526	256526	256526	-
NM_004168.4(SDHA):c.1988C>T (p.Ser663Phe)	6389	SDHA	Uncertain significance	1060503719	RCV000477211\|RCV000574185;	N	MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	5	256528	256528	NC_000005.9:g.256528C>T	ClinGen:CA16611849	C0027672 Hereditary cancer-predisposing syndrome;
NM_004168.4(SDHA):c.1989C>T (p.Ser663=)	6389	SDHA	Likely benign	1554002913	RCV000649464;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	256529	256529	5:g.256529C>T	ClinGen:CA442659766	C1855008 252011 Mitochondrial complex II deficiency;
NM_004168.4(SDHA):c.1989C>G (p.Ser663=)	6389	SDHA	Likely benign	1554002913	RCV000979776;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0013602,MedGen:C3279992,OMIM:614165, Orphanet:29072	5	256529	256529	5:g.256529C>G	-
NM_004168.4(SDHA):c.*75A>G	6389	SDHA	Uncertain significance	886060517	RCV000279520\|RCV000330444\|RCV000375689;	N	MONDO:MONDO:0017366,MedGen:C1708353, Orphanet:29072\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506	5	256610	256610	NC_000005.9:g.256610A>G	ClinGen:CA10624441	C0023264 256000 Leigh syndrome;
NM_004168.4(SDHA):c.*102G>A	6389	SDHA	Uncertain significance	1009017730	RCV001152539\|RCV001152540\|RCV001152541;	N	MONDO:MONDO:0017366,MedGen:C1708353, Orphanet:29072\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506	5	256637	256637	5:g.256637G>A	-
NM_004168.4(SDHA):c.*133G>C	6389	SDHA	Conflicting interpretations of pathogenicity	193112615	RCV000285270\|RCV000334630\|RCV000379866;	N	MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506\|MONDO:MONDO:0017366,MedGen:C1708353, Orphanet:29072\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	5	256668	256668	NC_000005.9:g.256668G>C	ClinGen:CA10624444	C0023264 256000 Leigh syndrome;
NM_004168.4(SDHA):c.*179G>A	6389	SDHA	Uncertain significance	980815395	RCV001152542\|RCV001153826\|RCV001153827\|RCV002480550;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506\|MONDO:MONDO:0017366,MedGen:C1708353, Orphanet:29072\|MONDO:MONDO:0013339,MedGen:C3150898,OMIM:613642, Orphanet:154; MONDO:MONDO:003100	5	256714	256714	5:g.256714G>A	-
NM_004168.4(SDHA):c.*189C>T	6389	SDHA	Uncertain significance	185107377	RCV000309761\|RCV000340216\|RCV000396725;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506\|MONDO:MONDO:0017366,MedGen:C1708353, Orphanet:29072	5	256724	256724	NC_000005.9:g.256724C>T	ClinGen:CA10624327	C0023264 256000 Leigh syndrome;
NM_004168.4(SDHA):c.*249T>C	6389	SDHA	Conflicting interpretations of pathogenicity	189989110	RCV001153828\|RCV001153829\|RCV001153830;	N	MONDO:MONDO:0017366,MedGen:C1708353, Orphanet:29072\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0009723,MedGen:C0023264,OMIM:256000, Orphanet:506	5	256784	256784	5:g.256784T>C	-
NM_001042631.3(SDHAF1):c.-64C>G	644096	SDHAF1	Uncertain significance	886054354	RCV000350401;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	19	36486113	36486113	NC_000019.9:g.36486113C>G	ClinGen:CA10642654	C1855008 252011 Mitochondrial complex II deficiency;
NM_001042631.3(SDHAF1):c.3G>A (p.Met1Ile)	644096	SDHAF1	Uncertain significance	1976651034	RCV001122156;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	19	36486179	36486179	19:g.36486179G>A	-
NM_001042631.3(SDHAF1):c.29A>C (p.Gln10Pro)	644096	SDHAF1	Uncertain significance	1599670818	RCV000852381;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	19	36486205	36486205	19:g.36486205A>C	-
NM_001042631.3(SDHAF1):c.46C>T (p.Arg16Cys)	644096	SDHAF1	Uncertain significance	777257006	RCV001122157\|RCV003246705;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MeSH:D030342,MedGen:C0950123	19	36486222	36486222	19:g.36486222C>T	-
NM_001042631.3(SDHAF1):c.49G>A (p.Asp17Asn)	644096	SDHAF1	Uncertain significance	538225779	RCV001122158;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	19	36486225	36486225	19:g.36486225G>A	-
NM_001042631.3(SDHAF1):c.117T>C (p.His39=)	644096	SDHAF1	Uncertain significance	754546603	RCV001124925;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	19	36486293	36486293	19:g.36486293T>C	-
NM_001042631.3(SDHAF1):c.156C>A (p.Tyr52Ter)	644096	SDHAF1	Conflicting interpretations of pathogenicity	768768823	RCV000304255\|RCV001332725\|RCV002272202;	N	MedGen:CN517202\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0030935,MedGen:C5436933,OMIM:619166	19	36486332	36486332	19:g.36486332C>A	ClinGen:CA9393678	CN517202 not provided;
NM_001042631.3(SDHAF1):c.319G>T (p.Ala107Ser)	644096	SDHAF1	Uncertain significance	956984428	RCV001291676;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	19	36486495	36486495	36486495	-
NM_001042631.3(SDHAF1):c.333C>G (p.Arg111=)	644096	SDHAF1	Benign/Likely benign	76336581	RCV000173197\|RCV000403258\|RCV000676630;	N	MedGen:CN169374\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MedGen:C3661900	19	36486509	36486509	NC_000019.9:g.36486509C>G	ClinGen:CA302686	C1855008 252011 Mitochondrial complex II deficiency;
NM_001042631.3(SDHAF1):c.334C>T (p.Pro112Ser)	644096	SDHAF1	Conflicting interpretations of pathogenicity	78119534	RCV000128020\|RCV000996848\|RCV001124926;	N	MedGen:CN169374\|MedGen:C3661900\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	19	36486510	36486510	19:g.36486510C>T	ClinGen:CA293458	CN169374 not specified;
NM_001042631.3(SDHAF1):c.*5C>A	644096	SDHAF1	Uncertain significance	1234271175	RCV001335598;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	19	36486529	36486529	36486529	-
NM_001042631.3(SDHAF1):c.*66G>A	644096	SDHAF1	Uncertain significance	1976659752	RCV001124927;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	19	36486590	36486590	19:g.36486590G>A	-
NM_001042631.3(SDHAF1):c.*156G>T	644096	SDHAF1	Benign/Likely benign	115204084	RCV000301279\|RCV001643024;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MedGen:C3661900	19	36486680	36486680	NC_000019.9:g.36486680G>T	ClinGen:CA10648565	C1855008 252011 Mitochondrial complex II deficiency;
NM_001042631.3(SDHAF1):c.*229C>T	644096	SDHAF1	Conflicting interpretations of pathogenicity	144661239	RCV001124928\|RCV001574400;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MedGen:C3661900	19	36486753	36486753	19:g.36486753C>T	-
NM_001042631.3(SDHAF1):c.*248C>T	644096	SDHAF1	Uncertain significance	552373950	RCV001124929;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	19	36486772	36486772	19:g.36486772C>T	-
NM_001042631.3(SDHAF1):c.*323C>G	644096	SDHAF1	Uncertain significance	757546678	RCV001125898;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	19	36486847	36486847	19:g.36486847C>G	-
NM_001042631.3(SDHAF1):c.*327C>A	644096	SDHAF1	Uncertain significance	1252756289	RCV001125899;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	19	36486851	36486851	19:g.36486851C>A	-
NM_001042631.3(SDHAF1):c.*329G>C	644096	SDHAF1	Uncertain significance	886054355	RCV000356291;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	19	36486853	36486853	NC_000019.9:g.36486853G>C	ClinGen:CA10648566	C1855008 252011 Mitochondrial complex II deficiency;
NM_001042631.3(SDHAF1):c.*622A>G	644096	SDHAF1	Benign	7925	RCV000261418;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	19	36487146	36487146	NC_000019.9:g.36487146A>G	ClinGen:CA10642655	C1855008 252011 Mitochondrial complex II deficiency;
NM_001042631.3(SDHAF1):c.*682A>T	644096	SDHAF1	Uncertain significance	554739627	RCV000298005;	N	MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208	19	36487206	36487206	NC_000019.9:g.36487206A>T	ClinGen:CA10652385	C1855008 252011 Mitochondrial complex II deficiency;
NM_003002.4(SDHD):c.205G>A (p.Glu69Lys)	6392	SDHD	Pathogenic/Likely pathogenic	202198133	RCV000144171\|RCV000484125\|RCV001290090\|RCV002415627\|RCV002515941;	N	MONDO:MONDO:0030937,MedGen:C5436934,OMIM:619167\|MedGen:C3661900\|MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|Human Phenotype Ontology:HP:0002666,MONDO:MONDO:0008233,MedGen	11	111959626	111959626	NC_000011.9:g.111959626G>A	ClinGen:CA016681,UniProtKB:O14521#VAR_074105,OMIM:602690.0029	C3554516 Cowden syndrome 3;
NM_003002.4(SDHD):c.335C>T (p.Thr112Ile)	6392	SDHD	Uncertain significance	199869408	RCV000455598\|RCV000760070\|RCV000764954\|RCV001020081\|RCV002229661;	N	MedGen:CN169374\|MedGen:C3661900\|MONDO:MONDO:0011740,MedGen:C1847319,OMIM:606864, Orphanet:97286; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0008192,MedGen:C3494181,OMIM:168000, Orphanet:29072; Human Phenotype Ontology:HP:00026	11	111965549	111965549	NC_000011.9:g.111965549C>T	ClinGen:CA071254	C3554516 Cowden syndrome 3;
NM_003002.4(SDHD):c.421T>C (p.Tyr141His)	6392	SDHD	Uncertain significance	1394514096	RCV000764955\|RCV000986023\|RCV002233358\|RCV003165869;	N	MONDO:MONDO:0011740,MedGen:C1847319,OMIM:606864, Orphanet:97286; MONDO:MONDO:0100294,MedGen:C5700310,OMIM:252011, Orphanet:3208; MONDO:MONDO:0008192,MedGen:C3494181,OMIM:168000, Orphanet:29072; Human Phenotype Ontology:HP:0002666,MONDO:MONDO:0008233,MedGen:C0	11	111965635	111965635	11:g.111965635T>C	-	C3554516 Cowden syndrome 3;

MSeqDR Portal

Ensembl Gene ID	Associated Gene Name	LSDB Genes	LSDB Variants	clinVar hits	Description	Disease id
ENSG00000073578	SDHA	1	3	1973	succinate dehydrogenase complex, subunit A, flavoprotein (Fp) [Source:HGNC Symbol;Acc:10680]	00016
ENSG00000205138	SDHAF1	1	2	20	succinate dehydrogenase complex assembly factor 1 [Source:HGNC Symbol;Acc:33867]	00016
ENSG00000204370	SDHD	1	0	3	succinate dehydrogenase complex, subunit D, integral membrane protein [Source:HGNC Symbol;Acc:10683]	00016

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