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Examples Gene: MT-ND1, POLG, Region: M:1-1000 Variant: m.8993T>G, 1:g.10042757T>C rs3888511 MSCV_0000006, ClinVar: RCV000000015, Disease: Leigh syndrome, Phenotype: Retinopathy

MSeqDR Mitochondrial Disease Portal

*:HP: HPO terms, UMDF: 1= Disease, ND: NAMDC terms.
Most Studied CPEO, Complex I Deficiency, COXPD1, Leigh, LHON, MELAS, MERRF, Myopathy, SANDO

Disease Browser
Parent Node: Multiple Endocrine Neoplasia (D009377)
..Starting node ..Multiple Endocrine Neoplasia Type 1 (D018761)
Child Nodes:
Sister Nodes:
..Multiple Endocrine Neoplasia Type 1 (D018761)
..Multiple Endocrine Neoplasia Type 2a (D018813) 1
..Multiple Endocrine Neoplasia Type 2b (D018814) 1
..Multiple Endocrine Neoplasia, Type IV (C567059)
Human Disease MESH is developed by UMLS. Further data from MedGen, OMIM,ClinVar, CTD

Term ID:

8254

Name:

Multiple Endocrine Neoplasia Type 1

Definition:

A form of multiple endocrine neoplasia that is characterized by the combined occurrence of tumors in the PARATHYROID GLANDS, the PITUITARY GLAND, and the PANCREATIC ISLETS. The resulting clinical signs include HYPERPARATHYROIDISM; HYPERCALCEMIA; HYPERPROLACTINEMIA; CUSHING DISEASE; GASTRINOMA; and ZOLLINGER-ELLISON SYNDROME. This disease is due to loss-of-function of the MEN1 gene, a tumor suppressor gene (GENES, TUMOR SUPPRESSOR) on CHROMOSOME 11 (Locus: 11q13).

Alternative IDs:

DO:DOID:10017|OMIM:131100

ParentIDs:

MESH:D009377

TreeNumbers:

C04.588.322.400.500 |C04.651.600.500 |C04.700.630.500 |C16.320.700.630.500 |C19.344.400.500

Synonyms:

Slim Mappings:

Cancer|Endocrine system disease|Genetic disease (inborn)

Reference:

MedGen: D018761
MeSH: D018761
OMIM: 131100;
MSeqDR :
Genes: MEN1;

Phenotypes

1	HP:0000006	Autosomal dominant inheritance
2	HP:0000820	Abnormality of the thyroid gland
3	HP:0009720	Adenoma sebaceum
4	HP:0008256	Adrenocortical adenoma
5	HP:0000957	Cafe-au-lait spot
6	HP:0100570	Carcinoid tumor
7	HP:0007449	Confetti-like hypopigmented macules
8	HP:0002014	Diarrhea
9	HP:0100633	Esophagitis
10	HP:0030404	Glucagonoma
11	HP:0000845	Growth hormone excess
12	HP:0003072	Hypercalcemia
13	HP:0001943	Hypoglycemia
14	HP:0003118	Increased circulating cortisol level
15	HP:0012197	Insulinoma
16	HP:0008261	Pancreatic islet cell adenoma
17	HP:0002897	Parathyroid adenoma
18	HP:0004398	Peptic ulcer
19	HP:0002893	Pituitary adenoma
20	HP:0006767	Pituitary prolactin cell adenoma
21	HP:0040278	Prolactinoma
22	HP:0001031	Subcutaneous lipoma
23	HP:0002044	Zollinger-Ellison syndrome

Disease Causing ClinVar Variants

Variation_Name	GeneID	GeneSymbol	ClinicalSignificance	dbSNP	RCVaccession	TestedInGTR	PhenotypeIDs	Chromosome	Start	Stop	HGVS_g	OtherIDs	Disease_ClinVar
NM_000051.4(ATM):c.7381C>A (p.Arg2461Ser)	472	ATM	Uncertain significance	-1	RCV003328120;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	108201014	108201014		-
NM_024529.5(CDC73):c.70G>T (p.Glu24Ter)	79577	CDC73	Likely pathogenic	-1	RCV003233053;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	1	193091400	193091400		-
NC_000011.10:g.(?_64803514)_(64810132_?)del	4221	MEN1	Pathogenic	-1	RCV000471021;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64570986	64577604		-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NC_000011.10:g.(?_64803514)_(64804816_?)del	4221	MEN1	Pathogenic	-1	RCV000456206;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64570986	64572288		-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_000244.3(MEN1):c.1366_*820del1303 (p.Val456_Ter(616_?)(?))	4221	MEN1	Pathogenic	-1	RCV000694224;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64570986	64572288	11:g.64570986_64571084del	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.*794G>A	4221	MEN1	Benign/Likely benign	117705251	RCV000323655\|RCV000380647;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|Human Phenotype Ontology:HP:0000843,MONDO:MONDO:0001741,MedGen:C0020502	11	64571012	64571012	NC_000011.9:g.64571012C>T	ClinGen:CA10638984	C0020502 Hyperparathyroidism;
NM_001370259.2(MEN1):c.*693T>C	4221	MEN1	Uncertain significance	1229690026	RCV001103229\|RCV001103228;	N	Human Phenotype Ontology:HP:0000843,MONDO:MONDO:0001741,MedGen:C0020502\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571113	64571113	11:g.64571113A>G	-
NM_001370259.2(MEN1):c.*470A>G	4221	MEN1	Conflicting interpretations of pathogenicity	778272737	RCV000302380\|RCV000359433\|RCV000736006\|RCV002248514;	N	Human Phenotype Ontology:HP:0000843,MONDO:MONDO:0001741,MedGen:C0020502\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0007052,MedGen:C4538355,OMIM:102200, Orphanet:314777, Orphanet:963\|MedGen:CN169374	11	64571336	64571336	11:g.64571336T>C	ClinGen:CA10635265	C0020502 Hyperparathyroidism;
NM_001370259.2(MEN1):c.*438C>T	4221	MEN1	Uncertain significance	886048474	RCV000305835\|RCV000399525;	N	Human Phenotype Ontology:HP:0000843,MONDO:MONDO:0001741,MedGen:C0020502\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571368	64571368	11:g.64571368G>A	ClinGen:CA10639624	C0020502 Hyperparathyroidism;
NM_001370259.2(MEN1):c.*400G>A	4221	MEN1	Uncertain significance	1351825181	RCV001105142\|RCV001105141;	N	Human Phenotype Ontology:HP:0000843,MONDO:MONDO:0001741,MedGen:C0020502\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571406	64571406	11:g.64571406C>T	-
NM_001370259.2(MEN1):c.*392G>A	4221	MEN1	Uncertain significance	886048475	RCV000271312\|RCV000363607;	N	Human Phenotype Ontology:HP:0000843,MONDO:MONDO:0001741,MedGen:C0020502\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571414	64571414	11:g.64571414C>T	ClinGen:CA10631161	C0020502 Hyperparathyroidism;
NM_001370259.2(MEN1):c.*373G>C	4221	MEN1	Uncertain significance	886048476	RCV000328807\|RCV000367135;	N	Human Phenotype Ontology:HP:0000843,MONDO:MONDO:0001741,MedGen:C0020502\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571433	64571433	11:g.64571433C>G	ClinGen:CA10639630	C0020502 Hyperparathyroidism;
NM_001370259.2(MEN1):c.*341C>G	4221	MEN1	Uncertain significance	892949876	RCV001105143\|RCV001105144;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|Human Phenotype Ontology:HP:0000843,MONDO:MONDO:0001741,MedGen:C0020502	11	64571465	64571465	11:g.64571465G>C	-
NM_001370259.2(MEN1):c.*307T>G	4221	MEN1	Benign/Likely benign	1804848	RCV000278044\|RCV000389312\|RCV001582939;	N	Human Phenotype Ontology:HP:0000843,MONDO:MONDO:0001741,MedGen:C0020502\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:CN517202	11	64571499	64571499	11:g.64571499A>C	ClinGen:CA10638988	C0020502 Hyperparathyroidism;
NM_001370259.2(MEN1):c.*302C>T	4221	MEN1	Benign/Likely benign	1804849	RCV000317316\|RCV000374227\|RCV001612967;	N	Human Phenotype Ontology:HP:0000843,MONDO:MONDO:0001741,MedGen:C0020502\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900	11	64571504	64571504	11:g.64571504G>A	ClinGen:CA10631163	C0020502 Hyperparathyroidism;
NM_001370259.2(MEN1):c.*272T>C	4221	MEN1	Uncertain significance	563783609	RCV000282016\|RCV000339408;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|Human Phenotype Ontology:HP:0000843,MONDO:MONDO:0001741,MedGen:C0020502	11	64571534	64571534	11:g.64571534A>G	ClinGen:CA10631164	C0020502 Hyperparathyroidism;
NM_001370259.2(MEN1):c.*245C>T	4221	MEN1	Uncertain significance	1941463518	RCV001106270\|RCV001106271;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|Human Phenotype Ontology:HP:0000843,MONDO:MONDO:0001741,MedGen:C0020502	11	64571561	64571561	11:g.64571561G>A	-
NM_001370259.2(MEN1):c.*185C>T	4221	MEN1	Benign/Likely benign	111895237	RCV000285411\|RCV000398124;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|Human Phenotype Ontology:HP:0000843,MONDO:MONDO:0001741,MedGen:C0020502	11	64571621	64571621	11:g.64571621G>A	ClinGen:CA10631169	C0020502 Hyperparathyroidism;
NM_001370259.2(MEN1):c.1351-2_*132del	4221	MEN1	Pathogenic	1565634591	RCV000704250;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571674	64572290	11:g.64571674_64571772del	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.*126C>T	4221	MEN1	Conflicting interpretations of pathogenicity	138595686	RCV001108501\|RCV001108502\|RCV001615115;	N	Human Phenotype Ontology:HP:0000843,MONDO:MONDO:0001741,MedGen:C0020502\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900	11	64571680	64571680	11:g.64571680G>A	-
NM_001370259.2(MEN1):c.*104C>T	4221	MEN1	Uncertain significance	886048477	RCV000342836\|RCV000398139;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|Human Phenotype Ontology:HP:0000843,MONDO:MONDO:0001741,MedGen:C0020502	11	64571702	64571702	11:g.64571702G>A	ClinGen:CA10639636	C0020502 Hyperparathyroidism;
NM_001370259.2(MEN1):c.*89G>A	4221	MEN1	Uncertain significance	886048478	RCV000308171\|RCV000365188;	N	Human Phenotype Ontology:HP:0000843,MONDO:MONDO:0001741,MedGen:C0020502\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571717	64571717	11:g.64571717C>T	ClinGen:CA10631171	C0020502 Hyperparathyroidism;
NC_000011.10:g.(?_64804324)_(64810716_?)del	4221	MEN1	Pathogenic	-1	RCV000811348;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571796	64578188		-
NC_000011.9:g.(?_64571796)_(64572298_?)del	4221	MEN1	Pathogenic	-1	RCV001963093;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571796	64572298	-1	-
NC_000011.10:g.(?_64804334)_(64810716_?)del	4221	MEN1	Pathogenic	-1	RCV001033318;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571806	64578188	-1	-
NC_000011.10:g.(?_64804334)_(64810716_?)dup	4221	MEN1	Uncertain significance	-1	RCV001033615;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571806	64578188	-1	-
NM_001370259.2(MEN1):c.1828C>T (p.Leu610Phe)	4221	MEN1	Uncertain significance	1941484511	RCV001312931\|RCV002411998;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64571811	64571811	64571811	-
NM_001370259.2(MEN1):c.1826G>T (p.Gly609Val)	4221	MEN1	Likely benign	1186858249	RCV000632145;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571813	64571813	11:g.64571813C>A	ClinGen:CA381177026	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1822A>G (p.Lys608Glu)	4221	MEN1	Uncertain significance	2136076826	RCV002407246\|RCV002033633;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571817	64571817	64571817	-
NM_001370259.2(MEN1):c.1821C>T (p.Arg607=)	4221	MEN1	Likely benign	2136076868	RCV002095002\|RCV002409487;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64571818	64571818	64571818	-
NM_001370259.2(MEN1):c.1819C>T (p.Arg607Cys)	4221	MEN1	Uncertain significance	770686655	RCV001306174;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571820	64571820	64571820	-
NM_001370259.2(MEN1):c.1818G>A (p.Gln606=)	4221	MEN1	Likely benign	-1	RCV002591243;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571821	64571821		-
NM_001370259.2(MEN1):c.1814G>A (p.Arg605Gln)	4221	MEN1	Uncertain significance	1555163002	RCV001036536;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571825	64571825	11:g.64571825C>T	-
NM_001370259.2(MEN1):c.1814G>T (p.Arg605Leu)	4221	MEN1	Uncertain significance	1555163002	RCV001209609;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571825	64571825	11:g.64571825C>A	-
NM_001370259.2(MEN1):c.1813C>G (p.Arg605Gly)	4221	MEN1	Uncertain significance	2136077141	RCV001890050;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571826	64571826	64571826	-
NM_001370259.2(MEN1):c.1812G>C (p.Lys604Asn)	4221	MEN1	Uncertain significance	-1	RCV003045046;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571827	64571827	NC_000011.9:g.64571827C>G	-
NM_001370259.2(MEN1):c.1806C>T (p.Phe602=)	4221	MEN1	Likely benign	1060503794	RCV001409455\|RCV003380582;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64571833	64571833	NC_000011.9:g.64571833G>A	ClinGen:CA16613659	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1805dup (p.Leu603fs)	4221	MEN1	Uncertain significance	1941486297	RCV001227670;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571833	64571834	11:g.64571833_64571834insA	-
NM_001370259.2(MEN1):c.1802C>G (p.Ser601Cys)	4221	MEN1	Uncertain significance	-1	RCV002298107;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571837	64571837	64571837	-
NM_001370259.2(MEN1):c.1801T>C (p.Ser601Pro)	4221	MEN1	Uncertain significance	1941486843	RCV001312354;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571838	64571838	64571838	-
NM_001370259.2(MEN1):c.1800_1801del (p.Ser601fs)	4221	MEN1	Uncertain significance	-1	RCV002824412;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571838	64571839	NC_000011.9:g.64571839_64571840del	-
NM_001370259.2(MEN1):c.1800G>T (p.Leu600=)	4221	MEN1	Likely benign	148825200	RCV000542760\|RCV000611916\|RCV002413456;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:CN169374\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64571839	64571839	NC_000011.9:g.64571839C>A	ClinGen:CA060968	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1800G>C (p.Leu600=)	4221	MEN1	Likely benign	-1	RCV002710753;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571839	64571839		-
NM_001370259.2(MEN1):c.1800G>A (p.Leu600=)	4221	MEN1	Likely benign	-1	RCV002833395;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571839	64571839		-
NM_001370259.2(MEN1):c.1798_1799del (p.Leu600fs)	4221	MEN1	Uncertain significance	1555163017	RCV000530307;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571840	64571841	11:g.64571840_64571841del	ClinGen:CA658656128	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1798C>T (p.Leu600=)	4221	MEN1	Likely benign	2136077489	RCV001465129;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571841	64571841	64571841	-
NM_001370259.2(MEN1):c.1797T>C (p.Thr599=)	4221	MEN1	Likely benign	2136077544	RCV001492126;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571842	64571842	64571842	-
NM_001370259.2(MEN1):c.1795A>G (p.Thr599Ala)	4221	MEN1	Uncertain significance	1941487702	RCV001305554;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571844	64571844	64571844	-
NM_001370259.2(MEN1):c.1794C>T (p.Tyr598=)	4221	MEN1	Likely benign	2136077605	RCV001434778;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571845	64571845	64571845	-
NM_001370259.2(MEN1):c.1790A>C (p.Asp597Ala)	4221	MEN1	Uncertain significance	-1	RCV002576214;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571849	64571849	NC_000011.9:g.64571849T>G	-
NM_001370259.2(MEN1):c.1787G>C (p.Ser596Thr)	4221	MEN1	Uncertain significance	2136077666	RCV001928626;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571852	64571852	64571852	-
NM_001370259.2(MEN1):c.1784C>G (p.Pro595Arg)	4221	MEN1	Uncertain significance	2136077699	RCV001904449;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571855	64571855	64571855	-
NM_001370259.2(MEN1):c.1783C>T (p.Pro595Ser)	4221	MEN1	Uncertain significance	2136077722	RCV002019268;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571856	64571856	64571856	-
NM_001370259.2(MEN1):c.1780A>G (p.Thr594Ala)	4221	MEN1	Uncertain significance	1941488490	RCV001263014;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571859	64571859	11:g.64571859T>C	-
NM_001370259.2(MEN1):c.1780A>C (p.Thr594Pro)	4221	MEN1	Uncertain significance	-1	RCV003029670;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571859	64571859	NC_000011.9:g.64571859T>G	-
NM_001370259.2(MEN1):c.1779C>T (p.Ser593=)	4221	MEN1	Likely benign	1157546350	RCV000559082\|RCV003362827;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64571860	64571860	11:g.64571860G>A	ClinGen:CA475163001	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1777T>C (p.Ser593Pro)	4221	MEN1	Conflicting interpretations of pathogenicity	1411766225	RCV000697463\|RCV003303155;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64571862	64571862	NC_000011.9:g.64571862A>G	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1775T>C (p.Val592Ala)	4221	MEN1	Uncertain significance	1941489030	RCV002036638\|RCV002398129;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64571864	64571864	64571864	-
NM_001370259.2(MEN1):c.1770G>C (p.Gln590His)	4221	MEN1	Uncertain significance	1470506250	RCV002039601;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571869	64571869	64571869	-
NM_001370259.2(MEN1):c.1762AAG[1] (p.Lys589del)	4221	MEN1	Uncertain significance	1303070443	RCV000694676\|RCV002397414;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64571872	64571874	NC_000011.9:g.64571873TTC[1]	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1764G>A (p.Lys588=)	4221	MEN1	Conflicting interpretations of pathogenicity	373669288	RCV000199306\|RCV000400551\|RCV000311483\|RCV000566719;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0017169,MedGen:C0027662,OMIM:PS131100, Orphanet:276161\|Human Phenotype Ontology:HP:0000843,MONDO:MONDO:0001741,MedGen:C0020502\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C	11	64571875	64571875	NC_000011.9:g.64571875C>T	ClinGen:CA060947	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1761G>A (p.Met587Ile)	4221	MEN1	Uncertain significance	1555163058	RCV000546677\|RCV003159747;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64571878	64571878	NC_000011.9:g.64571878C>T	ClinGen:CA381177410	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1758G>A (p.Gln586=)	4221	MEN1	Likely benign	759563305	RCV001419347;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571881	64571881	NC_000011.9:g.64571881C>T	ClinGen:CA060941	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1756C>T (p.Gln586Ter)	4221	MEN1	Likely pathogenic	-1	RCV003028068;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571883	64571883	NC_000011.9:g.64571883G>A	-
NM_001370259.2(MEN1):c.1755G>A (p.Val585=)	4221	MEN1	Likely benign	2136078442	RCV001498116\|RCV003382613;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64571884	64571884	64571884	-
NM_001370259.2(MEN1):c.1754T>G (p.Val585Gly)	4221	MEN1	Uncertain significance	1592629417	RCV000816259;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571885	64571885	11:g.64571885A>C	-
NM_001370259.2(MEN1):c.1754T>A (p.Val585Glu)	4221	MEN1	Uncertain significance	1592629417	RCV001341529;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571885	64571885	64571885	-
NM_001370259.2(MEN1):c.1749G>C (p.Ser583=)	4221	MEN1	Likely benign	765105348	RCV001012972\|RCV001428702;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571890	64571890	NC_000011.9:g.64571890C>G	ClinGen:CA060934	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1749G>T (p.Ser583=)	4221	MEN1	Likely benign	765105348	RCV001502503;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571890	64571890	64571890	-
NM_001370259.2(MEN1):c.1740G>C (p.Thr580=)	4221	MEN1	Likely benign	1114167530	RCV000490893\|RCV001460396;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571899	64571899	NC_000011.9:g.64571899C>G	ClinGen:CA475163136	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1740G>A (p.Thr580=)	4221	MEN1	Likely benign	1114167530	RCV001412596\|RCV002400106;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64571899	64571899	11:g.64571899C>T	-
NM_001370259.2(MEN1):c.1739del (p.Thr580fs)	4221	MEN1	Likely pathogenic	864622617	RCV000203927;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571900	64571900	11:g.64571900_64571900del	ClinGen:CA348208	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1739C>T (p.Thr580Met)	4221	MEN1	Uncertain significance	1941492703	RCV001212417;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571900	64571900	11:g.64571900G>A	-
NM_001370259.2(MEN1):c.1735C>T (p.Leu579Phe)	4221	MEN1	Uncertain significance	1328296968	RCV001058147\|RCV002402420;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64571904	64571904	11:g.64571904G>A	-
NM_001370259.2(MEN1):c.1732C>T (p.Gln578Ter)	4221	MEN1	Likely pathogenic	-1	RCV003062399;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571907	64571907	NC_000011.9:g.64571907G>A	-
NM_001370259.2(MEN1):c.1730T>C (p.Leu577Pro)	4221	MEN1	Conflicting interpretations of pathogenicity	794728634	RCV000182428\|RCV000491331\|RCV001852316;	N	MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571909	64571909	NC_000011.9:g.64571909A>G	ClinGen:CA009298	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1729C>T (p.Leu577=)	4221	MEN1	Likely benign	762744342	RCV000928594\|RCV002409200;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64571910	64571910	11:g.64571910G>A	-
NM_001370259.2(MEN1):c.1727A>C (p.Lys576Thr)	4221	MEN1	Uncertain significance	1941495030	RCV001229136;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571912	64571912	11:g.64571912T>G	-
NM_001370259.2(MEN1):c.1725C>G (p.Ile575Met)	4221	MEN1	Uncertain significance	1941495298	RCV001956774;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571914	64571914	64571914	-
NM_001370259.2(MEN1):c.1720G>A (p.Ala574Thr)	4221	MEN1	Uncertain significance	-1	RCV002294789;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571919	64571919	64571919	-
NM_001370259.2(MEN1):c.1718G>A (p.Ser573Asn)	4221	MEN1	Uncertain significance	1257993399	RCV001212802;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571921	64571921	11:g.64571921C>T	-
NM_001370259.2(MEN1):c.1713C>T (p.Asn571=)	4221	MEN1	Likely benign	1347492310	RCV002190054;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571926	64571926	64571926	-
NM_001370259.2(MEN1):c.1705A>G (p.Lys569Glu)	4221	MEN1	Uncertain significance	-1	RCV003010012;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571934	64571934	NC_000011.9:g.64571934T>C	-
NM_001370259.2(MEN1):c.1703C>T (p.Thr568Ile)	4221	MEN1	Conflicting interpretations of pathogenicity	751839903	RCV001052604\|RCV002400303;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64571936	64571936	11:g.64571936G>A	-
NM_001370259.2(MEN1):c.1703C>G (p.Thr568Ser)	4221	MEN1	Uncertain significance	751839903	RCV001342592;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571936	64571936	64571936	-
NM_001370259.2(MEN1):c.1701C>T (p.Ala567=)	4221	MEN1	Conflicting interpretations of pathogenicity	757417271	RCV000491209\|RCV000553378\|RCV001500075;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571938	64571938	NC_000011.9:g.64571938G>A	ClinGen:CA060907	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1699G>C (p.Ala567Pro)	4221	MEN1	Uncertain significance	1555163185	RCV000574893\|RCV003465261;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571940	64571940	NC_000011.9:g.64571940C>G	ClinGen:CA381177639	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1698G>A (p.Val566=)	4221	MEN1	Likely benign	2136080002	RCV001470899;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571941	64571941	64571941	-
NM_001370259.2(MEN1):c.1695G>T (p.Leu565=)	4221	MEN1	Likely benign	767677287	RCV000564918\|RCV000756336\|RCV001087239;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571944	64571944	NC_000011.9:g.64571944C>A	ClinGen:CA060897	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1693C>T (p.Leu565=)	4221	MEN1	Likely benign	1251646520	RCV001407162;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571946	64571946	64571946	-
NM_001370259.2(MEN1):c.1692G>T (p.Leu564=)	4221	MEN1	Likely benign	367581776	RCV000632156\|RCV001012772;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64571947	64571947	11:g.64571947C>A	ClinGen:CA060893	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1691T>C (p.Leu564Pro)	4221	MEN1	Uncertain significance	2136080204	RCV002013733\|RCV002407289;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64571948	64571948	64571948	-
NM_001370259.2(MEN1):c.1689G>A (p.Glu563=)	4221	MEN1	Likely benign	1178628764	RCV001478555\|RCV002414156;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64571950	64571950	64571950	-
NM_001370259.2(MEN1):c.1686G>A (p.Lys562=)	4221	MEN1	Likely benign	2136080412	RCV002152865;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571953	64571953	64571953	-
NM_001370259.2(MEN1):c.1682T>C (p.Met561Thr)	4221	MEN1	Uncertain significance	1941501393	RCV001893760;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571957	64571957	64571957	-
NM_001370259.2(MEN1):c.1672_1679del (p.Met558fs)	4221	MEN1	Pathogenic	1941501683	RCV001065726;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571960	64571967	11:g.64571960_64571967del	-
NM_001370259.2(MEN1):c.1677G>A (p.Lys559=)	4221	MEN1	Likely benign	2136080688	RCV002162680;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571962	64571962	64571962	-
NM_001370259.2(MEN1):c.1674dup (p.Lys559fs)	4221	MEN1	Pathogenic	1565635941	RCV000689715;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571964	64571965	NC_000011.9:g.64571965dup	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1674G>A (p.Met558Ile)	4221	MEN1	Uncertain significance	-1	RCV002405919\|RCV003097096;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571965	64571965	64571965	-
NM_001370259.2(MEN1):c.1642_1673delinsCC (p.Gly548_Met558delinsPro)	4221	MEN1	Pathogenic	-1	RCV003001978;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571966	64571997	NC_000011.9:g.64571966_64571997delinsGG	-
NM_001370259.2(MEN1):c.1667AGA[1] (p.Lys557del)	4221	MEN1	Conflicting interpretations of pathogenicity	794728661	RCV000182464\|RCV001223385\|RCV003407673;	N	MedGen:C3661900\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|	11	64571967	64571969	NC_000011.9:g.64571967TCT[1]	ClinGen:CA009279	CN517202 not provided;
NM_001370259.2(MEN1):c.1670del (p.Lys557fs)	4221	MEN1	Pathogenic	1592630079	RCV000824610;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571969	64571969	11:g.64571969_64571969del	-
NM_001370259.2(MEN1):c.1670A>T (p.Lys557Met)	4221	MEN1	Uncertain significance	-1	RCV002297479;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571969	64571969	64571969	-
NM_001370259.2(MEN1):c.1665_1668del (p.Ser555fs)	4221	MEN1	Pathogenic/Likely pathogenic	1114167510	RCV000491205\|RCV001258063;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571971	64571974	11:g.64571971_64571974del	ClinGen:CA645369569	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1668G>A (p.Glu556=)	4221	MEN1	Likely benign	2136080910	RCV001446044;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571971	64571971	64571971	-
NM_001370259.2(MEN1):c.1664G>A (p.Ser555Asn)	4221	MEN1	Pathogenic/Likely pathogenic	863224527	RCV000199920\|RCV000507111\|RCV000491766;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:CN169374\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64571975	64571975	NC_000011.9:g.64571975C>T	ClinGen:CA338972	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1660C>T (p.Gln554Ter)	4221	MEN1	Pathogenic	794728631	RCV000182425\|RCV000491870\|RCV000542312;	N	MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571979	64571979	NC_000011.9:g.64571979G>A	ClinGen:CA009272	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1660del (p.Gln554fs)	4221	MEN1	Pathogenic	2136081113	RCV001881459;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571979	64571979	64571978	-
NM_001370259.2(MEN1):c.1659C>T (p.Phe553=)	4221	MEN1	Conflicting interpretations of pathogenicity	1299138529	RCV000568387\|RCV002060519;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571980	64571980	NC_000011.9:g.64571980G>A	ClinGen:CA475163495	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1657_1658del (p.Phe553fs)	4221	MEN1	Pathogenic	2136081238	RCV001951114;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571981	64571982	64571980	-
NM_001370259.2(MEN1):c.1658T>A (p.Phe553Tyr)	4221	MEN1	Uncertain significance	-1	RCV003035231;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571981	64571981	NC_000011.9:g.64571981A>T	-
NM_001370259.2(MEN1):c.1656T>C (p.Thr552=)	4221	MEN1	Likely benign	143423552	RCV000490999\|RCV000679253\|RCV001086364\|RCV003235049;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:CN169374	11	64571983	64571983	NC_000011.9:g.64571983A>G	ClinGen:CA009268	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1654A>G (p.Thr552Ala)	4221	MEN1	Uncertain significance	121913035	RCV001928013;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571985	64571985	64571985	-
NM_001370259.2(MEN1):c.1653C>T (p.Leu551=)	4221	MEN1	Likely benign	1592630324	RCV001405627;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571986	64571986	11:g.64571986G>A	-
NM_001370259.2(MEN1):c.1653C>G (p.Leu551=)	4221	MEN1	Likely benign	1592630324	RCV000977248\|RCV002400136;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64571986	64571986	11:g.64571986G>C	-
NM_001370259.2(MEN1):c.1651C>T (p.Leu551Phe)	4221	MEN1	Uncertain significance	990141724	RCV001246504;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571988	64571988	11:g.64571988G>A	-
NM_001370259.2(MEN1):c.1649T>G (p.Val550Gly)	4221	MEN1	Uncertain significance	1941506496	RCV001045807;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571990	64571990	11:g.64571990A>C	-
NM_001370259.2(MEN1):c.1649T>C (p.Val550Ala)	4221	MEN1	Uncertain significance	1941506496	RCV002042767;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571990	64571990	64571990	-
NM_001370259.2(MEN1):c.1648G>C (p.Val550Leu)	4221	MEN1	Uncertain significance	562257963	RCV000793423\|RCV002307616\|RCV002388419;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64571991	64571991	11:g.64571991C>G	-
NM_001370259.2(MEN1):c.1648G>T (p.Val550Leu)	4221	MEN1	Conflicting interpretations of pathogenicity	562257963	RCV001232905\|RCV003166426;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64571991	64571991	11:g.64571991C>A	-
NM_001370259.2(MEN1):c.1648G>A (p.Val550Met)	4221	MEN1	Uncertain significance	562257963	RCV001958521;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571991	64571991	64571991	-
NM_001370259.2(MEN1):c.1647A>G (p.Pro549=)	4221	MEN1	Likely benign	2136081746	RCV002212227\|RCV002391185;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64571992	64571992	64571992	-
NM_001370259.2(MEN1):c.1646C>T (p.Pro549Leu)	4221	MEN1	Uncertain significance	-1	RCV002676777;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571993	64571993	NC_000011.9:g.64571993G>A	-
NM_001370259.2(MEN1):c.1641G>A (p.Glu547=)	4221	MEN1	Likely benign	1555163295	RCV000632168\|RCV003302993;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64571998	64571998	NC_000011.9:g.64571998C>T	ClinGen:CA475163594	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1640A>G (p.Glu547Gly)	4221	MEN1	Likely benign	914488914	RCV000529882\|RCV001012531;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64571999	64571999	NC_000011.9:g.64571999T>C	ClinGen:CA223911789	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1640A>C (p.Glu547Ala)	4221	MEN1	Uncertain significance	914488914	RCV001874788;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64571999	64571999	64571999	-
NM_001370259.2(MEN1):c.1633CCG[3] (p.Pro546dup)	4221	MEN1	Conflicting interpretations of pathogenicity	774350463	RCV000168092\|RCV002399595;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572000	64572001	11:g.64572000_64572001insCGG	ClinGen:CA334256	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1639G>A (p.Glu547Lys)	4221	MEN1	Uncertain significance	1941508162	RCV001043456;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572000	64572000	11:g.64572000C>T	-
NM_001370259.2(MEN1):c.1638G>A (p.Pro546=)	4221	MEN1	Benign/Likely benign	368783097	RCV000491078\|RCV000679252\|RCV000838399\|RCV001086369;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN169374\|MedGen:C3661900\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572001	64572001	NC_000011.9:g.64572001C>T	ClinGen:CA060874	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1637C>T (p.Pro546Leu)	4221	MEN1	Uncertain significance	779413959	RCV000167886\|RCV002399594;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572002	64572002	NC_000011.9:g.64572002G>A	ClinGen:CA009249	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1636C>T (p.Pro546Ser)	4221	MEN1	Uncertain significance	2136082158	RCV001890494;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572003	64572003	64572003	-
NM_001370259.2(MEN1):c.1635G>A (p.Pro545=)	4221	MEN1	Likely benign	1349729840	RCV000553596\|RCV001012390;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572004	64572004	NC_000011.9:g.64572004C>T	ClinGen:CA475163627	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1634C>T (p.Pro545Leu)	4221	MEN1	Uncertain significance	1592630610	RCV001889766\|RCV002397822;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572005	64572005	64572005	-
NM_001370259.2(MEN1):c.1633C>T (p.Pro545Ser)	4221	MEN1	Uncertain significance	1941510179	RCV001063209\|RCV002402444;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572006	64572006	11:g.64572006G>A	-
NM_001370259.2(MEN1):c.1630C>T (p.Pro544Ser)	4221	MEN1	Uncertain significance	1387157979	RCV001050468\|RCV001529168;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:CN517202	11	64572009	64572009	11:g.64572009G>A	-
NM_001370259.2(MEN1):c.1628C>T (p.Ser543Leu)	4221	MEN1	Uncertain significance	1592630661	RCV000796623;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572011	64572011	11:g.64572011G>A	-
NM_001370259.2(MEN1):c.1626A>G (p.Ala542=)	4221	MEN1	Likely benign	2136082421	RCV002081377;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572013	64572013	64572013	-
NM_001370259.2(MEN1):c.1625C>T (p.Ala542Val)	4221	MEN1	Uncertain significance	1941511257	RCV001344675;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572014	64572014	64572014	-
NM_001370259.2(MEN1):c.1621_1622delinsGA (p.Thr541Glu)	4221	MEN1	Uncertain significance	1941511781	RCV001342856;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572017	64572018	64572017	-
NM_001370259.2(MEN1):c.1621= (p.Thr541=)	4221	MEN1	Conflicting interpretations of pathogenicity	2959656	RCV000034785\|RCV000082334\|RCV000210359\|RCV001084452;	N	MedGen:C3661900\|MedGen:CN169374\|Human Phenotype Ontology:HP:0008200,Human Phenotype Ontology:HP:0008254,MONDO:MONDO:0010837,MedGen:C0221002\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572018	64572018	11:g.64572018T>.	ClinGen:CA009240	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1621A>G (p.Thr541Ala)	4221	MEN1	Benign	2959656	RCV000121334\|RCV000860147\|RCV002227065;	N	MedGen:CN169374\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900	11	64572018	64572018	11:g.64572018T>C	ClinGen:CA060856	CN169374 not specified;
NM_001370259.2(MEN1):c.1621A>C (p.Thr541Pro)	4221	MEN1	Uncertain significance	2959656	RCV000793172;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572018	64572018	11:g.64572018T>G	-
NM_001370259.2(MEN1):c.1620_1621inv (p.Thr541Ala)	4221	MEN1	Likely benign	-1	RCV001484742;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572018	64572019	64572018	-
NM_001370259.2(MEN1):c.1620_1621delinsAG (p.Thr541Ala)	4221	MEN1	Likely benign	2136082604	RCV001425924;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572018	64572019	64572018	-
NM_001370259.2(MEN1):c.1620C>T (p.Pro540=)	4221	MEN1	Likely benign	928470958	RCV002542299\|RCV003169386;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572019	64572019	11:g.64572019G>A	-
NM_001370259.2(MEN1):c.1619C>G (p.Pro540Arg)	4221	MEN1	Uncertain significance	780844361	RCV001895597;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572020	64572020	64572020	-
NM_001370259.2(MEN1):c.1618C>T (p.Pro540Ser)	4221	MEN1	Conflicting interpretations of pathogenicity	745404679	RCV000231689\|RCV000575915\|RCV000679251\|RCV000735331\|RCV001103324;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900\|Human Phenotype Ontology:HP:0002415,Human Phenotype Ontology:HP:0006926,Human Phenotype Ontology:H	11	64572021	64572021	NC_000011.9:g.64572021G>A	ClinGen:CA009233	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1616C>T (p.Ala539Val)	4221	MEN1	Uncertain significance	-1	RCV002394861\|RCV003097010;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572023	64572023	64572023	-
NM_001370259.2(MEN1):c.1610T>G (p.Val537Gly)	4221	MEN1	Likely benign	775422717	RCV000814868\|RCV002390649;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572029	64572029	11:g.64572029A>C	-
NM_001370259.2(MEN1):c.1609G>A (p.Val537Met)	4221	MEN1	Conflicting interpretations of pathogenicity	1057521847	RCV000436800\|RCV000491562\|RCV001374124;	N	MedGen:CN169374\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572030	64572030	11:g.64572030C>T	ClinGen:CA16606963	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1609G>C (p.Val537Leu)	4221	MEN1	Likely benign	1057521847	RCV001991590;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572030	64572030	64572030	-
NM_001370259.2(MEN1):c.1609del (p.Val537fs)	4221	MEN1	Pathogenic/Likely pathogenic	2136083128	RCV001963123\|RCV002388935\|RCV003120788;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	11	64572030	64572030	64572029	-
NM_001370259.2(MEN1):c.1608G>A (p.Gln536=)	4221	MEN1	Likely benign	1055457298	RCV000564252\|RCV001001327;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572031	64572031	11:g.64572031C>T	ClinGen:CA223911872	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1607A>G (p.Gln536Arg)	4221	MEN1	Uncertain significance	762867287	RCV001012352\|RCV001860704;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572032	64572032	11:g.64572032T>C	-
NM_001370259.2(MEN1):c.1605T>C (p.Ala535=)	4221	MEN1	Likely benign	2136083318	RCV001436580;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572034	64572034	64572034	-
NM_001370259.2(MEN1):c.1602G>A (p.Thr534=)	4221	MEN1	Likely benign	1592631034	RCV001457349\|RCV002400015;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572037	64572037	11:g.64572037C>T	-
NM_001370259.2(MEN1):c.1602G>C (p.Thr534=)	4221	MEN1	Likely benign	1592631034	RCV001459611\|RCV002400077;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572037	64572037	11:g.64572037C>G	-
NM_001370259.2(MEN1):c.1602G>T (p.Thr534=)	4221	MEN1	Likely benign	1592631034	RCV001430739\|RCV002405008;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572037	64572037	64572037	-
NM_001370259.2(MEN1):c.1601C>T (p.Thr534Met)	4221	MEN1	Uncertain significance	1192690654	RCV001907841;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572038	64572038	64572038	-
NM_001370259.2(MEN1):c.1594G>T (p.Gly532Cys)	4221	MEN1	Conflicting interpretations of pathogenicity	587780843	RCV000123383\|RCV000572942;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572045	64572045	NC_000011.9:g.64572045C>A	ClinGen:CA009225	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1592G>A (p.Gly531Asp)	4221	MEN1	Uncertain significance	1941517219	RCV001342991;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572047	64572047	64572047	-
NM_001370259.2(MEN1):c.1591G>A (p.Gly531Ser)	4221	MEN1	Uncertain significance	1592631128	RCV002041525;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572048	64572048	64572048	-
NM_001370259.2(MEN1):c.1590del (p.Gly531fs)	4221	MEN1	Pathogenic	886039421	RCV000255871\|RCV002518753;	N	MedGen:CN517202\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572049	64572049	11:g.64572049_64572049del	ClinGen:CA10588526	CN517202 not provided;
NM_001370259.2(MEN1):c.1589A>C (p.Glu530Ala)	4221	MEN1	Uncertain significance	1565636654	RCV000679250\|RCV002544693;	N	MedGen:CN517202\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572050	64572050	NC_000011.9:g.64572050T>G	-	CN517202 not provided;
NM_001370259.2(MEN1):c.1588G>C (p.Glu530Gln)	4221	MEN1	Uncertain significance	762145604	RCV001363933;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572051	64572051	64572051	-
NM_001370259.2(MEN1):c.1584C>G (p.Gly528=)	4221	MEN1	Likely benign	1592631208	RCV001478735\|RCV002400154;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572055	64572055	11:g.64572055G>C	-
NM_001370259.2(MEN1):c.1583G>A (p.Gly528Asp)	4221	MEN1	Uncertain significance	1555163392	RCV000632144;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572056	64572056	11:g.64572056C>T	ClinGen:CA381178330	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1580G>A (p.Arg527Gln)	4221	MEN1	Conflicting interpretations of pathogenicity	1085307502	RCV000489063\|RCV001039164\|RCV002404280;	N	MedGen:C3661900\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572059	64572059	11:g.64572059C>T	ClinGen:CA381178349	CN169374 not specified;
NM_001370259.2(MEN1):c.1579C>T (p.Arg527Ter)	4221	MEN1	Pathogenic/Likely pathogenic	104894261	RCV000018168\|RCV000182423\|RCV000491431\|RCV000515522;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|	11	64572060	64572060	11:g.64572060G>A	ClinGen:CA009219,OMIM:613733.0012	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1578C>A (p.Ala526=)	4221	MEN1	Likely benign	767655504	RCV000205589\|RCV002256119;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572061	64572061	11:g.64572061G>T	ClinGen:CA060797	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1578C>T (p.Ala526=)	4221	MEN1	Likely benign	767655504	RCV001012250\|RCV001492730;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572061	64572061	11:g.64572061G>A	-
NM_001370259.2(MEN1):c.1577C>T (p.Ala526Val)	4221	MEN1	Uncertain significance	-1	RCV002297141;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572062	64572062	64572062	-
NM_001370259.2(MEN1):c.1576G>A (p.Ala526Thr)	4221	MEN1	Uncertain significance	1295193195	RCV002044109\|RCV002545336;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MeSH:D030342,MedGen:C0950123	11	64572063	64572063	64572063	-
NM_001370259.2(MEN1):c.1574del (p.Thr525fs)	4221	MEN1	Pathogenic	1114167514	RCV000490847\|RCV001206955;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572065	64572065	11:g.64572065_64572065del	ClinGen:CA645369553	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1569T>G (p.Ala523=)	4221	MEN1	Likely benign	1592631415	RCV000921904\|RCV002400016;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572070	64572070	11:g.64572070A>C	-
NM_001370259.2(MEN1):c.1569T>A (p.Ala523=)	4221	MEN1	Uncertain significance	1592631415	RCV001318030;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572070	64572070	64572070	-
NM_001370259.2(MEN1):c.1567G>C (p.Ala523Pro)	4221	MEN1	Conflicting interpretations of pathogenicity	760683615	RCV000168386\|RCV002399596;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572072	64572072	NC_000011.9:g.64572072C>G	ClinGen:CA009213	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1567G>A (p.Ala523Thr)	4221	MEN1	Conflicting interpretations of pathogenicity	760683615	RCV000632113\|RCV002271541\|RCV002404746;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:CN169374\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572072	64572072	NC_000011.9:g.64572072C>T	ClinGen:CA060785	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1566C>T (p.Val522=)	4221	MEN1	Likely benign	-1	RCV002405528\|RCV003096944;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572073	64572073		-
NM_001370259.2(MEN1):c.1564dup (p.Val522fs)	4221	MEN1	Likely pathogenic	1941522995	RCV001174739;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572074	64572075	11:g.64572074_64572075insC	-
NM_001370259.2(MEN1):c.1565T>C (p.Val522Ala)	4221	MEN1	Uncertain significance	1592631462	RCV001221787;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572074	64572074	11:g.64572074A>G	-
NM_001370259.2(MEN1):c.1564G>C (p.Val522Leu)	4221	MEN1	Uncertain significance	1060499983	RCV000462233\|RCV001012142;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572075	64572075	NC_000011.9:g.64572075C>G	ClinGen:CA16613661	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1562C>T (p.Thr521Ile)	4221	MEN1	Uncertain significance	1565636898	RCV000701461\|RCV003165870;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572077	64572077	NC_000011.9:g.64572077G>A	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1562C>G (p.Thr521Ser)	4221	MEN1	Uncertain significance	1565636898	RCV000814100;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572077	64572077	11:g.64572077G>C	-
NM_001370259.2(MEN1):c.1561A>T (p.Thr521Ser)	4221	MEN1	Uncertain significance	1565636917	RCV000691457;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572078	64572078	NC_000011.9:g.64572078T>A	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1561A>C (p.Thr521Pro)	4221	MEN1	Uncertain significance	1565636917	RCV001057973\|RCV002402418;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572078	64572078	11:g.64572078T>G	-
NM_001370259.2(MEN1):c.1561A>G (p.Thr521Ala)	4221	MEN1	Uncertain significance	1565636917	RCV001996378;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572078	64572078	64572078	-
NM_001370259.2(MEN1):c.1560G>A (p.Gly520=)	4221	MEN1	Likely benign	969035156	RCV002194046;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572079	64572079	64572079	-
NM_001370259.2(MEN1):c.1558G>A (p.Gly520Arg)	4221	MEN1	Conflicting interpretations of pathogenicity	1427043628	RCV001350060\|RCV002404831;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572081	64572081	64572081	-
NM_001370259.2(MEN1):c.1556del (p.Pro519fs)	4221	MEN1	Pathogenic	2136084930	RCV001384744\|RCV001564679;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900	11	64572083	64572083	64572082	-
NM_001370259.2(MEN1):c.1554T>C (p.Pro518=)	4221	MEN1	Likely benign	2136084986	RCV002184005;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572085	64572085	64572085	-
NM_001370259.2(MEN1):c.1554T>G (p.Pro518=)	4221	MEN1	Likely benign	-1	RCV002578638;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572085	64572085		-
NM_001370259.2(MEN1):c.1552C>T (p.Pro518Ser)	4221	MEN1	Uncertain significance	1204943413	RCV000812581\|RCV002397677;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572087	64572087	11:g.64572087G>A	-
NM_001370259.2(MEN1):c.1549A>T (p.Lys517Ter)	4221	MEN1	Pathogenic	794728630	RCV000491042\|RCV001852315;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572090	64572090	11:g.64572090T>A	ClinGen:CA009207	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1548dup (p.Lys517fs)	4221	MEN1	Pathogenic/Likely pathogenic	761695866	RCV000182442\|RCV001174576\|RCV002399657;	N	MedGen:C3661900\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572090	64572091	NC_000011.9:g.64572092dup	ClinGen:CA306384	CN517202 not provided;
NM_001370259.2(MEN1):c.1546dup (p.Arg516fs)	4221	MEN1	Pathogenic	767319284	RCV000018171\|RCV000269197\|RCV000491230\|RCV000548407;	N	Human Phenotype Ontology:HP:0030445,MONDO:MONDO:0006041,MedGen:C0280089\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572092	64572093	11:g.64572092_64572093insG	ClinGen:CA6082217,OMIM:613733.0015,OMIM:613733.0033	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1547G>A (p.Arg516Gln)	4221	MEN1	Uncertain significance	1565637104	RCV000807352;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572092	64572092	11:g.64572092C>T	-
NM_001370259.2(MEN1):c.1546del (p.Arg516fs)	4221	MEN1	Pathogenic	767319284	RCV000182439\|RCV000228926\|RCV001012050;	N	MedGen:C3661900\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572093	64572093	NC_000011.9:g.64572099del	ClinGen:CA009199,OMIM:613733.0028	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1546C>G (p.Arg516Gly)	4221	MEN1	Conflicting interpretations of pathogenicity	763160290	RCV000695921\|RCV002397421;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572093	64572093	NC_000011.9:g.64572093G>C	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1546C>T (p.Arg516Trp)	4221	MEN1	Uncertain significance	763160290	RCV000708705\|RCV001321256;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572093	64572093	NC_000011.9:g.64572093G>A	-	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1545C>A (p.Pro515=)	4221	MEN1	Likely benign	1555163491	RCV000632161;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572094	64572094	NC_000011.9:g.64572094G>T	ClinGen:CA475162960	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1544C>G (p.Pro515Arg)	4221	MEN1	Uncertain significance	1941528728	RCV001306264;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572095	64572095	64572095	-
NM_001370259.2(MEN1):c.1543C>T (p.Pro515Ser)	4221	MEN1	Uncertain significance	779466487	RCV000709156;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572096	64572096	NC_000011.9:g.64572096G>A	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1542C>T (p.Pro514=)	4221	MEN1	Likely benign	1592631827	RCV001012112\|RCV002550775;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572097	64572097	11:g.64572097G>A	-
NM_001370259.2(MEN1):c.1542C>G (p.Pro514=)	4221	MEN1	Likely benign	1592631827	RCV002125639;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572097	64572097	64572097	-
NM_001370259.2(MEN1):c.1541C>G (p.Pro514Arg)	4221	MEN1	Uncertain significance	753022747	RCV000233918\|RCV000561798;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572098	64572098	11:g.64572098G>C	ClinGen:CA060761	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1541C>T (p.Pro514Leu)	4221	MEN1	Uncertain significance	753022747	RCV000540194\|RCV002404383;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572098	64572098	NC_000011.9:g.64572098G>A	ClinGen:CA381178580	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1532_1541del (p.Val511fs)	4221	MEN1	Pathogenic	1941529928	RCV001233728;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572098	64572107	11:g.64572098_64572107del	-
NM_001370259.2(MEN1):c.1541C>A (p.Pro514His)	4221	MEN1	Uncertain significance	753022747	RCV001974376\|RCV003170328;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572098	64572098	64572098	-
NM_001370259.2(MEN1):c.1540C>A (p.Pro514Thr)	4221	MEN1	Conflicting interpretations of pathogenicity	150202288	RCV000232118\|RCV002401910;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572099	64572099	NC_000011.9:g.64572099G>T	ClinGen:CA060747	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1540C>T (p.Pro514Ser)	4221	MEN1	Likely benign	150202288	RCV000687699\|RCV002397376;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572099	64572099	NC_000011.9:g.64572099G>A	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1539del (p.Arg516fs)	4221	MEN1	Pathogenic/Likely pathogenic	1592631908	RCV001011983\|RCV001860686;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572100	64572100	11:g.64572100_64572100del	-
NM_001370259.2(MEN1):c.1539A>T (p.Gly513=)	4221	MEN1	Likely benign	1941530792	RCV001209604\|RCV002402620;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572100	64572100	11:g.64572100T>A	-
NM_001370259.2(MEN1):c.1536A>G (p.Ser512=)	4221	MEN1	Likely benign	2136085950	RCV001501188\|RCV002405188;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572103	64572103	64572103	-
NM_001370259.2(MEN1):c.1535C>T (p.Ser512Leu)	4221	MEN1	Conflicting interpretations of pathogenicity	141679530	RCV000168243\|RCV000276552\|RCV000561706\|RCV001558467\|RCV001818404\|RCV003416048;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|Human Phenotype Ontology:HP:0000843,MONDO:MONDO:0001741,MedGen:C0020502\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900\|MedGen:CN169374\|	11	64572104	64572104	NC_000011.9:g.64572104G>A	ClinGen:CA009193	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1533_1534dup (p.Ser512fs)	4221	MEN1	Pathogenic	794728659	RCV000182462\|RCV000491410\|RCV001382418;	N	MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572104	64572105	NC_000011.9:g.64572105AC[3]	ClinGen:CA306434	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1535C>G (p.Ser512Ter)	4221	MEN1	Pathogenic	141679530	RCV000550819;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572104	64572104	NC_000011.9:g.64572104G>C	ClinGen:CA381178620	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1532dup (p.Ser512fs)	4221	MEN1	Pathogenic	1941531859	RCV001215902;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572106	64572107	11:g.64572106_64572107insA	-
NM_001370259.2(MEN1):c.1533G>A (p.Val511=)	4221	MEN1	Likely benign	-1	RCV003046278;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572106	64572106		-
NM_001370259.2(MEN1):c.1530A>C (p.Ala510=)	4221	MEN1	Likely benign	1941532417	RCV002107746;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572109	64572109	64572109	-
NM_001370259.2(MEN1):c.1529C>T (p.Ala510Val)	4221	MEN1	Uncertain significance	1356056436	RCV001968959;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572110	64572110	64572110	-
NM_001370259.2(MEN1):c.1526G>T (p.Gly509Val)	4221	MEN1	Uncertain significance	769355346	RCV000632099;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572113	64572113	NC_000011.9:g.64572113C>A	ClinGen:CA381178671	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1526G>A (p.Gly509Asp)	4221	MEN1	Uncertain significance	769355346	RCV001342594;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572113	64572113	64572113	-
NM_001370259.2(MEN1):c.1525G>A (p.Gly509Ser)	4221	MEN1	Uncertain significance	1941533809	RCV001225651;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572114	64572114	11:g.64572114C>T	-
NM_001370259.2(MEN1):c.1522C>A (p.Gln508Lys)	4221	MEN1	Conflicting interpretations of pathogenicity	386833403	RCV000455940\|RCV000464409\|RCV000575663;	N	MedGen:CN169374\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572117	64572117	NC_000011.9:g.64572117G>T	ClinGen:CA060724	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1522C>T (p.Gln508Ter)	4221	MEN1	Pathogenic	386833403	RCV001197197;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572117	64572117	11:g.64572117G>A	-
NM_001370259.2(MEN1):c.1521C>A (p.Gly507=)	4221	MEN1	Likely benign	1407833502	RCV000905665\|RCV001011968;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572118	64572118	11:g.64572118G>T	-
NM_001370259.2(MEN1):c.1519G>T (p.Gly507Cys)	4221	MEN1	Uncertain significance	1423874145	RCV000533671;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572120	64572120	11:g.64572120C>A	ClinGen:CA381178712	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1519G>A (p.Gly507Ser)	4221	MEN1	Conflicting interpretations of pathogenicity	1423874145	RCV001038797\|RCV002391105;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572120	64572120	11:g.64572120C>T	-
NM_001370259.2(MEN1):c.1518C>T (p.Thr506=)	4221	MEN1	Benign/Likely benign	749265222	RCV000228222\|RCV000576040;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572121	64572121	NC_000011.9:g.64572121G>A	ClinGen:CA060719	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1518C>A (p.Thr506=)	4221	MEN1	Likely benign	749265222	RCV002092532;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572121	64572121	64572121	-
NM_001370259.2(MEN1):c.1517C>T (p.Thr506Ile)	4221	MEN1	Uncertain significance	1347992299	RCV000694715\|RCV002388259;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572122	64572122	NC_000011.9:g.64572122G>A	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1516A>C (p.Thr506Pro)	4221	MEN1	Uncertain significance	1060499994	RCV000476839\|RCV001011879\|RCV001284274;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	11	64572123	64572123	NC_000011.9:g.64572123T>G	ClinGen:CA16613440	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1515C>T (p.Gly505=)	4221	MEN1	Uncertain significance	2136086851	RCV001965300;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572124	64572124	64572124	-
NM_001370259.2(MEN1):c.1514G>T (p.Gly505Val)	4221	MEN1	Uncertain significance	1320934898	RCV001361223;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572125	64572125	64572125	-
NM_001370259.2(MEN1):c.1514G>A (p.Gly505Asp)	4221	MEN1	Uncertain significance	1320934898	RCV001371635;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572125	64572125	64572125	-
NM_001370259.2(MEN1):c.1510C>G (p.Leu504Val)	4221	MEN1	Uncertain significance	1390530663	RCV001039930;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572129	64572129	11:g.64572129G>C	-
NM_001370259.2(MEN1):c.1509C>T (p.Gly503=)	4221	MEN1	Likely benign	-1	RCV002587303;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572130	64572130		-
NM_001370259.2(MEN1):c.1508G>A (p.Gly503Asp)	4221	MEN1	Benign/Likely benign	375804228	RCV000491076\|RCV000616587\|RCV001000155\|RCV001105230\|RCV001705900;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN169374\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|Human Phenotype Ontology:HP:0000843,MONDO:MONDO:0001741,MedGen:C0020502\|MedGen:C3661900	11	64572131	64572131	11:g.64572131C>T	ClinGen:CA009181	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1507G>T (p.Gly503Cys)	4221	MEN1	Uncertain significance	2136087052	RCV001959708;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572132	64572132	64572132	-
NM_001370259.2(MEN1):c.1506G>C (p.Lys502Asn)	4221	MEN1	Conflicting interpretations of pathogenicity	774296730	RCV000458972\|RCV000566191\|RCV003392264;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|	11	64572133	64572133	NC_000011.9:g.64572133C>G	ClinGen:CA060705	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1505dup (p.Leu504fs)	4221	MEN1	Pathogenic	1555163591	RCV000485290\|RCV001851142;	N	MedGen:CN517202\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572133	64572134	NC_000011.9:g.64572135dup	ClinGen:CA16619357	CN517202 not provided;
NM_001370259.2(MEN1):c.1503C>G (p.Asp501Glu)	4221	MEN1	Uncertain significance	2136087305	RCV001361936;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572136	64572136	64572136	-
NM_001370259.2(MEN1):c.1503C>T (p.Asp501=)	4221	MEN1	Likely benign	2136087305	RCV002149127;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572136	64572136	64572136	-
NM_001370259.2(MEN1):c.1502A>T (p.Asp501Val)	4221	MEN1	Uncertain significance	-1	RCV003470093;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572137	64572137		-
NM_001370259.2(MEN1):c.1500G>T (p.Leu500=)	4221	MEN1	Likely benign	-1	RCV002389934\|RCV003095253;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572139	64572139		-
NM_001370259.2(MEN1):c.1500G>A (p.Leu500=)	4221	MEN1	Likely benign	-1	RCV002948920;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572139	64572139		-
NM_001370259.2(MEN1):c.1499T>G (p.Leu500Arg)	4221	MEN1	Uncertain significance	1941538934	RCV002004867;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572140	64572140	64572140	-
NM_001370259.2(MEN1):c.1498C>T (p.Leu500=)	4221	MEN1	Likely benign	2136087489	RCV001465960\|RCV002396102;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572141	64572141	64572141	-
NM_001370259.2(MEN1):c.1497A>G (p.Ala499=)	4221	MEN1	Likely benign	1057121245	RCV000926922\|RCV002390934;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572142	64572142	11:g.64572142T>C	-
NM_001370259.2(MEN1):c.1495G>A (p.Ala499Thr)	4221	MEN1	Uncertain significance	761517398	RCV002257044\|RCV003094199;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572144	64572144	64572144	-
NM_001370259.2(MEN1):c.1494A>T (p.Pro498=)	4221	MEN1	Likely benign	1037335560	RCV000632157\|RCV003343963;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572145	64572145	NC_000011.9:g.64572145T>A	ClinGen:CA223912004	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1492C>G (p.Pro498Ala)	4221	MEN1	Uncertain significance	771842369	RCV000794008\|RCV002388425;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572147	64572147	11:g.64572147G>C	-
NM_001370259.2(MEN1):c.1491G>A (p.Lys497=)	4221	MEN1	Likely benign	2136087753	RCV002153292;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572148	64572148	64572148	-
NM_001370259.2(MEN1):c.1490A>G (p.Lys497Arg)	4221	MEN1	Uncertain significance	1941540571	RCV001237294;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572149	64572149	11:g.64572149T>C	-
NM_001370259.2(MEN1):c.1487A>G (p.Lys496Arg)	4221	MEN1	Uncertain significance	1270463727	RCV001899811\|RCV003164132;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572152	64572152	64572152	-
NM_001370259.2(MEN1):c.1485C>T (p.Pro495=)	4221	MEN1	Likely benign	2136087952	RCV002216818\|RCV003303744;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572154	64572154	64572154	-
NM_001370259.2(MEN1):c.1483C>T (p.Pro495Ser)	4221	MEN1	Uncertain significance	-1	RCV002397197\|RCV003095224;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572156	64572156	64572156	-
NM_001370259.2(MEN1):c.1482G>A (p.Pro494=)	4221	MEN1	Likely benign	773363654	RCV000473944\|RCV000571497;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572157	64572157	NC_000011.9:g.64572157C>T	ClinGen:CA060684	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1481C>T (p.Pro494Leu)	4221	MEN1	Uncertain significance	1060499993	RCV000469797\|RCV002393073;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572158	64572158	NC_000011.9:g.64572158G>A	ClinGen:CA16613663	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1479G>A (p.Pro493=)	4221	MEN1	Likely benign	546721780	RCV000473734\|RCV000571666\|RCV001721504;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	11	64572160	64572160	NC_000011.9:g.64572160C>T	ClinGen:CA060678	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1479G>T (p.Pro493=)	4221	MEN1	Likely benign	546721780	RCV001463618;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572160	64572160	11:g.64572160C>A	-
NM_001370259.2(MEN1):c.1478C>T (p.Pro493Leu)	4221	MEN1	Conflicting interpretations of pathogenicity	766604600	RCV000525912\|RCV001011715;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572161	64572161	NC_000011.9:g.64572161G>A	ClinGen:CA060672	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1478del (p.Pro493fs)	4221	MEN1	Pathogenic	-1	RCV002397070\|RCV003095215;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572161	64572161	64572160	-
NM_001370259.2(MEN1):c.1477C>T (p.Pro493Ser)	4221	MEN1	Uncertain significance	1941543089	RCV001307209\|RCV002393728;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572162	64572162	64572162	-
NM_001370259.2(MEN1):c.1476C>T (p.Pro492=)	4221	MEN1	Likely benign	2136088299	RCV001415917;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572163	64572163	64572163	-
NM_001370259.2(MEN1):c.1476C>G (p.Pro492=)	4221	MEN1	Likely benign	2136088299	RCV001489035\|RCV002396168;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572163	64572163	64572163	-
NM_001370259.2(MEN1):c.1475C>T (p.Pro492Leu)	4221	MEN1	Uncertain significance	1025851127	RCV001067347\|RCV002393324;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572164	64572164	11:g.64572164G>A	-
NM_001370259.2(MEN1):c.1473G>A (p.Glu491=)	4221	MEN1	Likely benign	1555163642	RCV000549772\|RCV002395304;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572166	64572166	11:g.64572166C>T	ClinGen:CA475163192	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1473del (p.Glu491fs)	4221	MEN1	Pathogenic	1555163646	RCV000632141;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572166	64572166	NC_000011.9:g.64572166del	ClinGen:CA658797662	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1471G>T (p.Glu491Ter)	4221	MEN1	Likely pathogenic	-1	RCV002796919;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572168	64572168	NC_000011.9:g.64572168C>A	-
NM_001370259.2(MEN1):c.1467A>G (p.Pro489=)	4221	MEN1	Likely benign	1592632826	RCV001451563\|RCV002390838;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572172	64572172	11:g.64572172T>C	-
NM_001370259.2(MEN1):c.1465C>T (p.Pro489Ser)	4221	MEN1	Uncertain significance	587778440	RCV000121335\|RCV000695300\|RCV002390271;	N	MedGen:CN169374\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572174	64572174	11:g.64572174G>A	ClinGen:CA009174	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1465C>A (p.Pro489Thr)	4221	MEN1	Uncertain significance	587778440	RCV001225532;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572174	64572174	11:g.64572174G>T	-
NM_001370259.2(MEN1):c.1464G>A (p.Lys488=)	4221	MEN1	Likely benign	-1	RCV002877434;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572175	64572175		-
NM_001370259.2(MEN1):c.1463A>G (p.Lys488Arg)	4221	MEN1	Uncertain significance	1941545858	RCV001054918\|RCV002393273;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572176	64572176	11:g.64572176T>C	-
NM_001370259.2(MEN1):c.1462A>C (p.Lys488Gln)	4221	MEN1	Uncertain significance	1941546101	RCV001239842;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572177	64572177	11:g.64572177T>G	-
NM_001370259.2(MEN1):c.1460C>T (p.Ser487Phe)	4221	MEN1	Uncertain significance	1941546652	RCV001049884;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572179	64572179	11:g.64572179G>A	-
NM_001370259.2(MEN1):c.1459T>C (p.Ser487Pro)	4221	MEN1	Uncertain significance	1057427859	RCV000537416;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572180	64572180	11:g.64572180A>G	ClinGen:CA381179189	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1458G>A (p.Glu486=)	4221	MEN1	Likely benign	1413990417	RCV000632154\|RCV003162806;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572181	64572181	11:g.64572181C>T	ClinGen:CA475163248	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1458G>C (p.Glu486Asp)	4221	MEN1	Uncertain significance	1413990417	RCV001925152;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572181	64572181	64572181	-
NM_001370259.2(MEN1):c.1456G>T (p.Glu486Ter)	4221	MEN1	Pathogenic	2136089217	RCV001381741;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572183	64572183	64572183	-
NM_001370259.2(MEN1):c.1454G>A (p.Arg485Gln)	4221	MEN1	Uncertain significance	2136089297	RCV001364790\|RCV002395819;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572185	64572185	64572185	-
NM_001370259.2(MEN1):c.1453C>T (p.Arg485Trp)	4221	MEN1	Uncertain significance	1254459338	RCV000556700\|RCV002395303;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572186	64572186	NC_000011.9:g.64572186G>A	ClinGen:CA381179244	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1453C>A (p.Arg485=)	4221	MEN1	Likely benign	1254459338	RCV001447463\|RCV002396035;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572186	64572186	64572186	-
NM_001370259.2(MEN1):c.1451G>A (p.Arg484Gln)	4221	MEN1	Uncertain significance	-1	RCV002394619\|RCV003095182;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572188	64572188	64572188	-
NM_001370259.2(MEN1):c.1450C>T (p.Arg484Trp)	4221	MEN1	Uncertain significance	1941548479	RCV001223765\|RCV003163744;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572189	64572189	11:g.64572189G>A	-
NM_001370259.2(MEN1):c.1450C>G (p.Arg484Gly)	4221	MEN1	Uncertain significance	-1	RCV002302275;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572189	64572189	64572189	-
NM_001370259.2(MEN1):c.1448C>T (p.Pro483Leu)	4221	MEN1	Uncertain significance	1941548759	RCV001038051;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572191	64572191	11:g.64572191G>A	-
NM_001370259.2(MEN1):c.1447C>T (p.Pro483Ser)	4221	MEN1	Uncertain significance	1565638021	RCV001316900;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572192	64572192	64572192	-
NM_001370259.2(MEN1):c.1444G>A (p.Gly482Ser)	4221	MEN1	Uncertain significance	2136089783	RCV001370699;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572195	64572195	64572195	-
NM_001370259.2(MEN1):c.1443G>A (p.Arg481=)	4221	MEN1	Likely benign	864622641	RCV001431309;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572196	64572196	11:g.64572196C>T	ClinGen:CA348087	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1435_1441del (p.Arg479fs)	4221	MEN1	Pathogenic	2136089949	RCV001873118;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572198	64572204	64572197	-
NM_001370259.2(MEN1):c.1441C>T (p.Arg481Trp)	4221	MEN1	Uncertain significance	-1	RCV003067611\|RCV003384319;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572198	64572198	NC_000011.9:g.64572198G>A	-
NM_001370259.2(MEN1):c.1439G>A (p.Arg480Gln)	4221	MEN1	Uncertain significance	1450318836	RCV001313840\|RCV002395671;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572200	64572200	64572200	-
NM_001370259.2(MEN1):c.1438C>T (p.Arg480Trp)	4221	MEN1	Uncertain significance	1301120298	RCV001362607;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572201	64572201	64572201	-
NM_001370259.2(MEN1):c.1437del (p.Arg480fs)	4221	MEN1	Pathogenic	1941550964	RCV001216756;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572202	64572202	11:g.64572202_64572202del	-
NM_001370259.2(MEN1):c.1437G>A (p.Arg479=)	4221	MEN1	Likely benign	1354865958	RCV002112667\|RCV002391240;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572202	64572202	64572202	-
NM_001370259.2(MEN1):c.1436G>C (p.Arg479Pro)	4221	MEN1	Uncertain significance	1555163716	RCV000544433;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572203	64572203	NC_000011.9:g.64572203C>G	ClinGen:CA381179331	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1435C>T (p.Arg479Trp)	4221	MEN1	Uncertain significance	1941551498	RCV001214980\|RCV003313192;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:CN517202	11	64572204	64572204	11:g.64572204G>A	-
NM_001370259.2(MEN1):c.1434C>T (p.Gly478=)	4221	MEN1	Conflicting interpretations of pathogenicity	200280309	RCV000234303\|RCV000570713;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572205	64572205	NC_000011.9:g.64572205G>A	ClinGen:CA060658	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1434C>G (p.Gly478=)	4221	MEN1	Likely benign	200280309	RCV002194315;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572205	64572205	64572205	-
NM_001370259.2(MEN1):c.1424_1432del (p.Ala475_Glu477del)	4221	MEN1	Uncertain significance	1290740194	RCV000801117\|RCV002388478;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572207	64572215	11:g.64572207_64572215del	-
NM_001370259.2(MEN1):c.1432G>A (p.Gly478Ser)	4221	MEN1	Uncertain significance	1941551993	RCV001312941\|RCV003284172;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572207	64572207	64572207	-
NM_001370259.2(MEN1):c.1431A>T (p.Glu477Asp)	4221	MEN1	Uncertain significance	863224811	RCV000197288\|RCV003343700;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572208	64572208	NC_000011.9:g.64572208T>A	ClinGen:CA337096	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1429G>T (p.Glu477Ter)	4221	MEN1	Pathogenic	863224526	RCV000198067\|RCV000254822\|RCV000490934;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572210	64572210	NC_000011.9:g.64572210C>A	ClinGen:CA337615	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1429G>C (p.Glu477Gln)	4221	MEN1	Uncertain significance	863224526	RCV000632101;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572210	64572210	NC_000011.9:g.64572210C>G	ClinGen:CA381179374	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1428G>C (p.Arg476=)	4221	MEN1	Likely benign	1555163730	RCV000536333\|RCV002256344;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572211	64572211	NC_000011.9:g.64572211C>G	ClinGen:CA475163376	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1428G>A (p.Arg476=)	4221	MEN1	Likely benign	1555163730	RCV001461279;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572211	64572211	64572211	-
NM_001370259.2(MEN1):c.1427G>A (p.Arg476Gln)	4221	MEN1	Uncertain significance	753185026	RCV001303949;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572212	64572212	64572212	-
NM_001370259.2(MEN1):c.1426C>T (p.Arg476Trp)	4221	MEN1	Uncertain significance	1941554063	RCV001316115;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572213	64572213	64572213	-
NM_001370259.2(MEN1):c.1424C>G (p.Ala475Gly)	4221	MEN1	Uncertain significance	-1	RCV002801474;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572215	64572215	NC_000011.9:g.64572215G>C	-
NM_001370259.2(MEN1):c.1407_1421del (p.Pro470_Glu474del)	4221	MEN1	Uncertain significance	1033303123	RCV000544503\|RCV002395302;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572218	64572232	NC_000011.9:g.64572224_64572238del	ClinGen:CA223912041	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1421A>G (p.Glu474Gly)	4221	MEN1	Uncertain significance	2136090940	RCV001931533;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572218	64572218	64572218	-
NM_001370259.2(MEN1):c.1420del (p.Glu474fs)	4221	MEN1	Pathogenic	1592633378	RCV000821759;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572219	64572219	11:g.64572219_64572219del	-
NM_001370259.2(MEN1):c.1419G>A (p.Glu473=)	4221	MEN1	Likely benign	2136091112	RCV002189244;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572220	64572220	64572220	-
NM_001370259.2(MEN1):c.1416C>T (p.Gly472=)	4221	MEN1	Likely benign	764509990	RCV000557060\|RCV000567684;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572223	64572223	NC_000011.9:g.64572223G>A	ClinGen:CA060641	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1406_1413dup (p.Gly472fs)	4221	MEN1	Pathogenic	1114167536	RCV000491271\|RCV000532169;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572225	64572226	NC_000011.9:g.64572228_64572235dup	ClinGen:CA645369556	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1414G>C (p.Gly472Arg)	4221	MEN1	Uncertain significance	1941555781	RCV001105231\|RCV001105232;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|Human Phenotype Ontology:HP:0000843,MONDO:MONDO:0001741,MedGen:C0020502	11	64572225	64572225	11:g.64572225C>G	-
NM_001370259.2(MEN1):c.1400_1413del (p.Ala467fs)	4221	MEN1	Pathogenic	1592633463	RCV000813744\|RCV002390646;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572226	64572239	11:g.64572226_64572239del	-
NM_001370259.2(MEN1):c.1413G>A (p.Trp471Ter)	4221	MEN1	Pathogenic	1941556077	RCV001213347\|RCV002393488;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572226	64572226	11:g.64572226C>T	-
NM_001370259.2(MEN1):c.1413G>T (p.Trp471Cys)	4221	MEN1	Uncertain significance	1941556077	RCV002007054;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572226	64572226	64572226	-
NM_001370259.2(MEN1):c.1412G>A (p.Trp471Ter)	4221	MEN1	Pathogenic	1060499991	RCV000474300;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572227	64572227	NC_000011.9:g.64572227C>T	ClinGen:CA16613444	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1412G>C (p.Trp471Ser)	4221	MEN1	Uncertain significance	1060499991	RCV001237059;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572227	64572227	11:g.64572227C>G	-
NM_001370259.2(MEN1):c.1410G>A (p.Pro470=)	4221	MEN1	Likely benign	1060503795	RCV001491814\|RCV002393174;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572229	64572229	NC_000011.9:g.64572229C>T	ClinGen:CA16613379	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1397_1410del (p.Glu466fs)	4221	MEN1	Likely pathogenic	-1	RCV003470101;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572229	64572242		-
NM_001370259.2(MEN1):c.1409C>T (p.Pro470Leu)	4221	MEN1	Conflicting interpretations of pathogenicity	750112288	RCV000167949\|RCV000569038\|RCV000602813\|RCV001105233;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN169374\|Human Phenotype Ontology:HP:0000843,MONDO:MONDO:0001741,MedGen:C0020502	11	64572230	64572230	11:g.64572230G>A	ClinGen:CA009169	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1408C>G (p.Pro470Ala)	4221	MEN1	Uncertain significance	1941557896	RCV001069437;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572231	64572231	11:g.64572231G>C	-
NM_001370259.2(MEN1):c.1393_1407del (p.Ala465_Glu469del)	4221	MEN1	Uncertain significance	1064792907	RCV000467609;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572232	64572246	NC_000011.9:g.64572233_64572247del	ClinGen:CA16613608	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1406A>C (p.Glu469Ala)	4221	MEN1	Uncertain significance	1565638407	RCV000709157\|RCV002388350;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572233	64572233	NC_000011.9:g.64572233T>G	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1391_1405dup (p.Ala464_Glu468dup)	4221	MEN1	Uncertain significance	1592633626	RCV001971565;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572233	64572234	64572233	-
NM_001370259.2(MEN1):c.1382_1404dup (p.Glu469fs)	4221	MEN1	Pathogenic	1555163780	RCV000476906;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572234	64572235	NC_000011.9:g.64572235_64572257dup	ClinGen:CA16613611	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1391_1405del (p.Ala464_Glu468del)	4221	MEN1	Uncertain significance	1592633626	RCV000816146;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572234	64572248	11:g.64572234_64572248del	-
NM_001370259.2(MEN1):c.1405G>C (p.Glu469Gln)	4221	MEN1	Uncertain significance	1182898331	RCV001066383\|RCV002393320;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572234	64572234	11:g.64572234C>G	-
NM_001370259.2(MEN1):c.1405G>A (p.Glu469Lys)	4221	MEN1	Uncertain significance	-1	RCV002389367\|RCV003095102;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572234	64572234	64572234	-
NM_001370259.2(MEN1):c.1404G>A (p.Glu468=)	4221	MEN1	Likely benign	755734265	RCV000565386\|RCV000827543\|RCV001081562;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572235	64572235	NC_000011.9:g.64572235C>T	ClinGen:CA060631	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1394_1402dup (p.462AEA[3])	4221	MEN1	Uncertain significance	1592633710	RCV000823122;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572236	64572237	11:g.64572236_64572237insCGGCCTCGG	-
NM_001370259.2(MEN1):c.1403A>G (p.Glu468Gly)	4221	MEN1	Uncertain significance	2136091899	RCV001891575;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572236	64572236	64572236	-
NM_001370259.2(MEN1):c.1402G>A (p.Glu468Lys)	4221	MEN1	Uncertain significance	1471493357	RCV001039197;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572237	64572237	11:g.64572237C>T	-
NM_001370259.2(MEN1):c.1401C>T (p.Ala467=)	4221	MEN1	Likely benign	878855190	RCV000230391\|RCV001011382;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572238	64572238	NC_000011.9:g.64572238G>A	ClinGen:CA6082218	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1383GGCCGAGGC[3] (p.462AEA[3])	4221	MEN1	Uncertain significance	772978541	RCV001907997\|RCV002388739;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572238	64572239	64572238	-
NM_001370259.2(MEN1):c.1383GGCCGAGGC[1] (p.462AEA[1])	4221	MEN1	Uncertain significance	772978541	RCV001310009;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572239	64572247	64572238	-
NM_001370259.2(MEN1):c.1399G>A (p.Ala467Thr)	4221	MEN1	Conflicting interpretations of pathogenicity	779589005	RCV000476178\|RCV002393071;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572240	64572240	NC_000011.9:g.64572240C>T	ClinGen:CA060627	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1399G>T (p.Ala467Ser)	4221	MEN1	Uncertain significance	-1	RCV003470098;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572240	64572240		-
NM_001370259.2(MEN1):c.1398G>T (p.Glu466Asp)	4221	MEN1	Uncertain significance	990566024	RCV000543695\|RCV001764533\|RCV002395301;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572241	64572241	11:g.64572241C>A	ClinGen:CA223912056	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1398G>A (p.Glu466=)	4221	MEN1	Likely benign	990566024	RCV001505584\|RCV002388561;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572241	64572241	64572241	-
NM_001370259.2(MEN1):c.1397A>T (p.Glu466Val)	4221	MEN1	Uncertain significance	1352053477	RCV000531071\|RCV001811030\|RCV002395300;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572242	64572242	11:g.64572242T>A	ClinGen:CA381179668	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1391_1396dup (p.Ala464_Ala465dup)	4221	MEN1	Uncertain significance	1555163821	RCV000632137;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572242	64572243	11:g.64572242_64572243insCGGCCG	ClinGen:CA658797664	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1396G>A (p.Glu466Lys)	4221	MEN1	Uncertain significance	1114167497	RCV000491124\|RCV001222306;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572243	64572243	NC_000011.9:g.64572243C>T	ClinGen:CA381179679	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1393_1396del (p.Ala465fs)	4221	MEN1	Pathogenic	-1	RCV003062402;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572243	64572246	NC_000011.9:g.64572245_64572248del	-
NM_001370259.2(MEN1):c.1396G>C (p.Glu466Gln)	4221	MEN1	Uncertain significance	-1	RCV003092618;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572243	64572243	NC_000011.9:g.64572243C>G	-
NM_001370259.2(MEN1):c.1395C>T (p.Ala465=)	4221	MEN1	Likely benign	748820252	RCV000475617\|RCV000565545;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572244	64572244	NC_000011.9:g.64572244G>A	ClinGen:CA060618	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1395C>G (p.Ala465=)	4221	MEN1	Likely benign	748820252	RCV000562592\|RCV002060414;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572244	64572244	NC_000011.9:g.64572244G>C	ClinGen:CA475163515	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1393del (p.Ala465fs)	4221	MEN1	Pathogenic	2136092552	RCV001910810;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572246	64572246	64572245	-
NM_001370259.2(MEN1):c.1392G>A (p.Ala464=)	4221	MEN1	Likely benign	754445482	RCV000227483\|RCV001011304\|RCV002465598;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN169374	11	64572247	64572247	11:g.64572247C>T	ClinGen:CA060614	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1391dup (p.Ala465fs)	4221	MEN1	Pathogenic	2136092746	RCV001386330;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572247	64572248	64572247	-
NM_001370259.2(MEN1):c.1375_1391dup (p.Ala467fs)	4221	MEN1	Pathogenic	2136092832	RCV001383288\|RCV002246367\|RCV002384547;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572247	64572248	64572247	-
NM_001370259.2(MEN1):c.1392G>C (p.Ala464=)	4221	MEN1	Likely benign	754445482	RCV001407863;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572247	64572247	64572247	-
NM_001370259.2(MEN1):c.1391_1392insCAGAGGCCGAGGC (p.Ala465fs)	4221	MEN1	Pathogenic	-1	RCV002811383;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572247	64572248	NC_000011.9:g.64572259_64572260insGGCCTCGGCCTCT	-
NM_001370259.2(MEN1):c.1391C>T (p.Ala464Val)	4221	MEN1	Conflicting interpretations of pathogenicity	778728934	RCV000459240\|RCV001810944\|RCV002393072;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572248	64572248	NC_000011.9:g.64572248G>A	ClinGen:CA060593	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1391C>A (p.Ala464Glu)	4221	MEN1	Uncertain significance	-1	RCV003054070\|RCV003170926;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572248	64572248	NC_000011.9:g.64572248G>T	-
NM_001370259.2(MEN1):c.1382_1389dup (p.Ala464fs)	4221	MEN1	Pathogenic	1114167531	RCV000491754\|RCV000632114;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572249	64572250	NC_000011.9:g.64572256_64572263dup	ClinGen:CA645369558	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1390G>C (p.Ala464Pro)	4221	MEN1	Uncertain significance	2136092866	RCV001951736;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572249	64572249	64572249	-
NM_001370259.2(MEN1):c.1390G>A (p.Ala464Thr)	4221	MEN1	Uncertain significance	2136092866	RCV001978494;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572249	64572249	64572249	-
NM_001370259.2(MEN1):c.1389G>C (p.Glu463Asp)	4221	MEN1	Uncertain significance	1555163863	RCV000555201;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572250	64572250	11:g.64572250C>G	ClinGen:CA381179724	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1388A>C (p.Glu463Ala)	4221	MEN1	Uncertain significance	-1	RCV002290207\|RCV002391402;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572251	64572251	64572251	-
NM_001370259.2(MEN1):c.1387G>C (p.Glu463Gln)	4221	MEN1	Uncertain significance	748102589	RCV001011215\|RCV001049805;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572252	64572252	11:g.64572252C>G	-
NM_001370259.2(MEN1):c.1387G>A (p.Glu463Lys)	4221	MEN1	Uncertain significance	748102589	RCV001222478\|RCV002393540;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572252	64572252	11:g.64572252C>T	-
NM_001370259.2(MEN1):c.1386C>G (p.Ala462=)	4221	MEN1	Likely benign	771827808	RCV001456315\|RCV002392719;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572253	64572253	NC_000011.9:g.64572253G>C	ClinGen:CA10582928	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1386C>T (p.Ala462=)	4221	MEN1	Likely benign	771827808	RCV000466838\|RCV002393175;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572253	64572253	NC_000011.9:g.64572253G>A	ClinGen:CA060584	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1386C>A (p.Ala462=)	4221	MEN1	Likely benign	771827808	RCV000542606\|RCV002395299;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572253	64572253	NC_000011.9:g.64572253G>T	ClinGen:CA060579	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1384G>C (p.Ala462Pro)	4221	MEN1	Uncertain significance	1941565557	RCV001062954;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572255	64572255	11:g.64572255C>G	-
NM_001370259.2(MEN1):c.1375_1382del (p.Ser459fs)	4221	MEN1	Pathogenic	1555163883	RCV000524622;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572257	64572264	NC_000011.9:g.64572257_64572264del	ClinGen:CA658656131	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1381G>C (p.Glu461Gln)	4221	MEN1	Uncertain significance	1941566282	RCV001315782;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572258	64572258	64572258	-
NM_001370259.2(MEN1):c.1380A>G (p.Arg460=)	4221	MEN1	Likely benign	2136093385	RCV001401510;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572259	64572259	64572259	-
NM_001370259.2(MEN1):c.1379G>A (p.Arg460Gln)	4221	MEN1	Uncertain significance	200035619	RCV000034783\|RCV000793682\|RCV003343606;	N	MedGen:C3661900\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572260	64572260	NC_000011.9:g.64572260C>T	ClinGen:CA009162	CN517202 not provided;
NM_001370259.2(MEN1):c.1379G>C (p.Arg460Pro)	4221	MEN1	Uncertain significance	200035619	RCV000456169\|RCV003168722;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572260	64572260	NC_000011.9:g.64572260C>G	ClinGen:CA16613450	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1378C>T (p.Arg460Ter)	4221	MEN1	Pathogenic	104894267	RCV000018172\|RCV000129526\|RCV000182421;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	11	64572261	64572261	11:g.64572261G>A	ClinGen:CA009155,OMIM:613733.0016	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1378C>A (p.Arg460=)	4221	MEN1	Likely benign	104894267	RCV000632165\|RCV003302992;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572261	64572261	NC_000011.9:g.64572261G>T	ClinGen:CA475163620	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1378C>G (p.Arg460Gly)	4221	MEN1	Uncertain significance	-1	RCV003110830;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572261	64572261	NC_000011.9:g.64572261G>C	-
NM_001370259.2(MEN1):c.1377C>T (p.Ser459=)	4221	MEN1	Likely benign	2136093597	RCV002089792;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572262	64572262	64572262	-
NM_001370259.2(MEN1):c.1374G>C (p.Val458=)	4221	MEN1	Likely benign	771297499	RCV001399223\|RCV002384575;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572265	64572265	64572265	-
NM_001370259.2(MEN1):c.1374G>A (p.Val458=)	4221	MEN1	Likely benign	771297499	RCV002206029;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572265	64572265	64572265	-
NM_001370259.2(MEN1):c.1370T>G (p.Ile457Arg)	4221	MEN1	Uncertain significance	1277747983	RCV001034908;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572269	64572269	11:g.64572269A>C	-
NM_001370259.2(MEN1):c.1369A>T (p.Ile457Leu)	4221	MEN1	Uncertain significance	1021589871	RCV002040424;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572270	64572270	64572270	-
NM_001370259.2(MEN1):c.1369A>C (p.Ile457Leu)	4221	MEN1	Uncertain significance	-1	RCV002810274;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572270	64572270	NC_000011.9:g.64572270T>G	-
NC_000011.10:g.64804807_64804818del	4221	MEN1	Pathogenic	760199250	RCV000018188;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572272	64572283		OMIM:613733.0032	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1367G>A (p.Arg456His)	4221	MEN1	Conflicting interpretations of pathogenicity	372468697	RCV000632093\|RCV002385985\|RCV003237966;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	11	64572272	64572272	NC_000011.9:g.64572272C>T	ClinGen:CA060552	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1366C>T (p.Arg456Cys)	4221	MEN1	Conflicting interpretations of pathogenicity	765306552	RCV001051925\|RCV002379553;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572273	64572273	11:g.64572273G>A	-
NM_001370259.2(MEN1):c.1366C>A (p.Arg456Ser)	4221	MEN1	Uncertain significance	-1	RCV003470094;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572273	64572273		-
NM_001370259.2(MEN1):c.1365G>A (p.Val455=)	4221	MEN1	Likely benign	-1	RCV002705764\|RCV003382923;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572274	64572274		-
NM_001370259.2(MEN1):c.1364T>A (p.Val455Glu)	4221	MEN1	Conflicting interpretations of pathogenicity	878855189	RCV000230771\|RCV001589199;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:CN517202	11	64572275	64572275	NC_000011.9:g.64572275A>T	ClinGen:CA10582929	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1363G>A (p.Val455Met)	4221	MEN1	Uncertain significance	1941570102	RCV001246568;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572276	64572276	11:g.64572276C>T	-
NM_001370259.2(MEN1):c.1351-3_1359del	4221	MEN1	Likely pathogenic	2136094253	RCV001377991\|RCV001810728;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900	11	64572280	64572291	64572279	-
NM_001370259.2(MEN1):c.1356dup (p.Gln453fs)	4221	MEN1	Pathogenic	2136094331	RCV001386127;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572282	64572283	64572282	-
NM_001370259.2(MEN1):c.1356G>T (p.Arg452=)	4221	MEN1	Likely benign	1180957953	RCV000874889\|RCV002381998;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572283	64572283	11:g.64572283C>A	-
NM_001370259.2(MEN1):c.1356G>A (p.Arg452=)	4221	MEN1	Likely benign	1180957953	RCV001505426;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572283	64572283	11:g.64572283C>T	-
NM_001370259.2(MEN1):c.1355G>C (p.Arg452Pro)	4221	MEN1	Conflicting interpretations of pathogenicity	775922507	RCV000571203\|RCV001377802;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572284	64572284	NC_000011.9:g.64572284C>G	ClinGen:CA381179936	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1355G>A (p.Arg452Gln)	4221	MEN1	Conflicting interpretations of pathogenicity	775922507	RCV000698881\|RCV002386229;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572284	64572284	NC_000011.9:g.64572284C>T	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1354C>T (p.Arg452Trp)	4221	MEN1	Conflicting interpretations of pathogenicity	863224810	RCV000200502\|RCV000491768;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572285	64572285	NC_000011.9:g.64572285G>A	ClinGen:CA339343	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1354C>A (p.Arg452=)	4221	MEN1	Likely benign	-1	RCV002617958;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572285	64572285		-
NM_001370259.2(MEN1):c.1353G>A (p.Val451=)	4221	MEN1	Likely benign	-1	RCV003037786;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572286	64572286		-
NM_001370259.2(MEN1):c.1351-1G>C	4221	MEN1	Pathogenic	794728629	RCV000540660;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572289	64572289	11:g.64572289C>G	ClinGen:CA009149	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1351-1G>A	4221	MEN1	Pathogenic	794728629	RCV000227993;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572289	64572289	NC_000011.9:g.64572289C>T	ClinGen:CA10582930	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1351-1G>T	4221	MEN1	Pathogenic	794728629	RCV001390118;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572289	64572289	64572289	-
NM_001370259.2(MEN1):c.1351-2A>G	4221	MEN1	Pathogenic	1060499986	RCV000457794;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572290	64572290	NC_000011.9:g.64572290T>C	ClinGen:CA16613456	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1351-4C>T	4221	MEN1	Conflicting interpretations of pathogenicity	764408631	RCV000571993\|RCV000679248\|RCV001105234\|RCV001083658\|RCV002267931;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900\|Human Phenotype Ontology:HP:0000843,MONDO:MONDO:0001741,MedGen:C0020502\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:CN169374	11	64572292	64572292	NC_000011.9:g.64572292G>A	ClinGen:CA060500	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1351-6G>A	4221	MEN1	Likely benign	1555164004	RCV000553033;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572294	64572294	11:g.64572294C>T	ClinGen:CA658656139	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1351-7G>A	4221	MEN1	Uncertain significance	1941572921	RCV001309308;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572295	64572295	64572295	-
NM_001370259.2(MEN1):c.1351-8T>G	4221	MEN1	Likely benign	751932519	RCV000198633;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572296	64572296	NC_000011.9:g.64572296A>C	ClinGen:CA338075	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1351-8T>C	4221	MEN1	Likely benign	751932519	RCV001397097;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572296	64572296	64572296	-
NM_001370259.2(MEN1):c.1351-9C>G	4221	MEN1	Uncertain significance	1592634740	RCV000801688;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572297	64572297	11:g.64572297G>C	-
NM_001370259.2(MEN1):c.1351-10A>G	4221	MEN1	Likely benign	757569943	RCV000528351;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572298	64572298	11:g.64572298T>C	ClinGen:CA060446	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1351-10del	4221	MEN1	Likely benign	-1	RCV002819530;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572298	64572298	NC_000011.9:g.64572298del	-
NM_001370259.2(MEN1):c.1351-11C>T	4221	MEN1	Likely benign	1941574613	RCV002204302;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572299	64572299	64572299	-
NM_001370259.2(MEN1):c.1351-11C>G	4221	MEN1	Likely benign	-1	RCV002716334;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572299	64572299	NC_000011.9:g.64572299G>C	-
NM_001370259.2(MEN1):c.1351-12C>T	4221	MEN1	Likely benign	2136094913	RCV002160052;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572300	64572300	64572300	-
NM_001370259.2(MEN1):c.1351-35ACCTTGCTCTC[3]	4221	MEN1	Likely benign	753219137	RCV002123136;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572301	64572302	64572301	-
NM_001370259.2(MEN1):c.1351-13C>T	4221	MEN1	Likely benign	2136094943	RCV002197740;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572301	64572301	64572301	-
NM_001370259.2(MEN1):c.1351-24_1351-14del	4221	MEN1	Likely benign	753219137	RCV002218121;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572302	64572312	64572301	-
NM_001370259.2(MEN1):c.1351-15T>G	4221	MEN1	Likely benign	2136095005	RCV002167129;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572303	64572303	64572303	-
NM_001370259.2(MEN1):c.1351-16C>G	4221	MEN1	Likely benign	766052368	RCV002144400;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572304	64572304	64572304	-
NM_001370259.2(MEN1):c.1351-16C>T	4221	MEN1	Likely benign	766052368	RCV002107896;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572304	64572304	64572304	-
NM_001370259.2(MEN1):c.1277_1350+28del	4221	MEN1	Likely pathogenic	1941598294	RCV001047541;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572478	64572579	11:g.64572478_64572576del	-
NM_001370259.2(MEN1):c.1350+19G>A	4221	MEN1	Likely benign	1331281610	RCV002111497;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572487	64572487	64572487	-
NM_001370259.2(MEN1):c.1350+18A>G	4221	MEN1	Likely benign	1190733461	RCV002170099;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572488	64572488	64572488	-
NM_001370259.2(MEN1):c.1350+12C>A	4221	MEN1	Likely benign	1186166424	RCV001994764;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572494	64572494	64572494	-
NM_001370259.2(MEN1):c.1350+1_1350+11del	4221	MEN1	Pathogenic	764570645	RCV000182441\|RCV000632087\|RCV002381592;	N	MedGen:C3661900\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572495	64572505	NC_000011.9:g.64572505_64572515del	ClinGen:CA017625	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1350+7G>A	4221	MEN1	Likely benign	2136099113	RCV001490747;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572499	64572499	64572499	-
NM_001370259.2(MEN1):c.1350+6G>A	4221	MEN1	Likely benign	746077651	RCV000687059;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572500	64572500	11:g.64572500C>T	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1350+4_1350+6del	4221	MEN1	Uncertain significance	1565639798	RCV000689757;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572500	64572502	11:g.64572500_64572502del	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1350+5G>A	4221	MEN1	Uncertain significance	1565639811	RCV000701682;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572501	64572501	NC_000011.9:g.64572501C>T	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1350+5G>T	4221	MEN1	Uncertain significance	1565639811	RCV001233104;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572501	64572501	11:g.64572501C>A	-
NM_001370259.2(MEN1):c.1350+2T>C	4221	MEN1	Likely pathogenic	1555164115	RCV000547647;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572504	64572504	11:g.64572504A>G	ClinGen:CA381180004	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1350+1G>C	4221	MEN1	Pathogenic	863223311	RCV002245308;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572505	64572505	64572505	-
NM_001370259.2(MEN1):c.1350G>C (p.Gln450His)	4221	MEN1	Conflicting interpretations of pathogenicity	1592636161	RCV001011030\|RCV001350334\|RCV002236080;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:CN169374	11	64572506	64572506	11:g.64572506C>G	-
NM_001370259.2(MEN1):c.1350G>A (p.Gln450=)	4221	MEN1	Uncertain significance	1592636161	RCV001369238;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572506	64572506	64572506	-
NM_001370259.2(MEN1):c.1346del (p.Gly449fs)	4221	MEN1	Pathogenic	1941603016	RCV001239413;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572510	64572510	11:g.64572510_64572510del	-
NM_001370259.2(MEN1):c.1344G>A (p.Glu448=)	4221	MEN1	Conflicting interpretations of pathogenicity	371339952	RCV001298168\|RCV002379999;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572512	64572512	64572512	-
NM_001370259.2(MEN1):c.1344G>C (p.Glu448Asp)	4221	MEN1	Uncertain significance	371339952	RCV001984224;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572512	64572512	64572512	-
NM_001370259.2(MEN1):c.1344G>T (p.Glu448Asp)	4221	MEN1	Uncertain significance	-1	RCV003130896;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572512	64572512	NC_000011.9:g.64572512C>A	-
NM_001370259.2(MEN1):c.1341T>G (p.Phe447Leu)	4221	MEN1	Uncertain significance	1325598637	RCV000710034\|RCV001759431\|RCV001868321;	N	MONDO:MONDO:0015027,MedGen:C4551961, Orphanet:99879\|MedGen:C3661900\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572515	64572515	NC_000011.9:g.64572515A>C	-
NM_001370259.2(MEN1):c.1341T>C (p.Phe447=)	4221	MEN1	Likely benign	1325598637	RCV001490015\|RCV002384805;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572515	64572515	64572515	-
NM_001370259.2(MEN1):c.1340T>C (p.Phe447Ser)	4221	MEN1	Likely pathogenic	1941604532	RCV001238238;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572516	64572516	11:g.64572516A>G	-
NM_001370259.2(MEN1):c.1337G>A (p.Arg446His)	4221	MEN1	Uncertain significance	1555164143	RCV000632094;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572519	64572519	NC_000011.9:g.64572519C>T	ClinGen:CA381180095	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1336C>T (p.Arg446Cys)	4221	MEN1	Uncertain significance	1592636375	RCV000803684;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572520	64572520	11:g.64572520G>A	-
NM_001370259.2(MEN1):c.1336C>A (p.Arg446Ser)	4221	MEN1	Uncertain significance	1592636375	RCV002039999;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572520	64572520	64572520	-
NM_001370259.2(MEN1):c.1334del (p.Gly445fs)	4221	MEN1	Pathogenic	1565640081	RCV000705923;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572522	64572522	NC_000011.9:g.64572523del	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1333G>T (p.Gly445Cys)	4221	MEN1	Uncertain significance	1555164153	RCV000632092;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572523	64572523	11:g.64572523C>A	ClinGen:CA381180110	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1330C>G (p.Leu444Val)	4221	MEN1	Uncertain significance	2136100021	RCV001969960;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572526	64572526	64572526	-
NM_001370259.2(MEN1):c.1329C>T (p.Ser443=)	4221	MEN1	Likely benign	2136100094	RCV002098762\|RCV002382353;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572527	64572527	64572527	-
NM_001370259.2(MEN1):c.1328C>A (p.Ser443Tyr)	4221	MEN1	Likely pathogenic	1060499981	RCV000467767;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572528	64572528	NC_000011.9:g.64572528G>T	ClinGen:CA16613613	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1324C>T (p.Gln442Ter)	4221	MEN1	Pathogenic	794728654	RCV000182456\|RCV000812559;	N	MedGen:CN517202\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572532	64572532	NC_000011.9:g.64572532G>A	ClinGen:CA009136	CN517202 not provided;
NM_001370259.2(MEN1):c.1323G>A (p.Val441=)	4221	MEN1	Likely benign	1941607604	RCV001459350\|RCV002384725;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572533	64572533	64572533	-
NM_001370259.2(MEN1):c.1317_1320del (p.Phe439fs)	4221	MEN1	Pathogenic	1941607846	RCV001204903;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572536	64572539	11:g.64572536_64572539del	-
NM_001370259.2(MEN1):c.1314C>G (p.Thr438=)	4221	MEN1	Likely benign	897481809	RCV000462500\|RCV002383842;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572542	64572542	NC_000011.9:g.64572542G>C	ClinGen:CA16613458	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1314C>T (p.Thr438=)	4221	MEN1	Likely benign	897481809	RCV000975483\|RCV003169491;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572542	64572542	11:g.64572542G>A	-
NM_001370259.2(MEN1):c.1313C>G (p.Thr438Ser)	4221	MEN1	Uncertain significance	-1	RCV002639023;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572543	64572543	NC_000011.9:g.64572543G>C	-
NM_001370259.2(MEN1):c.1311dup (p.Thr438fs)	4221	MEN1	Likely pathogenic	1555164184	RCV000662929;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572544	64572545	11:g.64572544_64572545insG	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1311del (p.Thr438fs)	4221	MEN1	Pathogenic	1555164184	RCV000806153;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572545	64572545	11:g.64572545_64572545del	-
NM_001370259.2(MEN1):c.1310C>T (p.Ala437Val)	4221	MEN1	Uncertain significance	1555164188	RCV000563093\|RCV001344201;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572546	64572546	NC_000011.9:g.64572546G>A	ClinGen:CA381180212	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1308G>T (p.Trp436Cys)	4221	MEN1	Pathogenic/Likely pathogenic	398124435	RCV000318762\|RCV000491855\|RCV000790656;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	11	64572548	64572548	NC_000011.9:g.64572548C>A	ClinGen:CA009127	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1307G>A (p.Trp436Ter)	4221	MEN1	Pathogenic	104894260	RCV000018167\|RCV000518947;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:CN517202	11	64572549	64572549	11:g.64572549C>T	ClinGen:CA009122,OMIM:613733.0011	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1306T>A (p.Trp436Arg)	4221	MEN1	Pathogenic/Likely pathogenic	104894259	RCV000018166\|RCV000255755;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:CN517202	11	64572550	64572550	11:g.64572550A>T	ClinGen:CA009116,UniProtKB:O00255#VAR_005464,OMIM:613733.0010	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1306T>C (p.Trp436Arg)	4221	MEN1	Pathogenic/Likely pathogenic	104894259	RCV000491105\|RCV001390119;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572550	64572550	11:g.64572550A>G	ClinGen:CA223912292	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1305_1306del (p.Trp436fs)	4221	MEN1	Pathogenic	-1	RCV003005580;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572550	64572551	NC_000011.9:g.64572550_64572551del	-
NM_001370259.2(MEN1):c.1294_1302del (p.Leu432_Val434del)	4221	MEN1	Uncertain significance	1555164218	RCV000662920;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572554	64572562	11:g.64572554_64572562del	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1300G>A (p.Val434Met)	4221	MEN1	Uncertain significance	767854775	RCV001235388\|RCV003166453;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572556	64572556	11:g.64572556C>T	-
NM_001370259.2(MEN1):c.1299T>C (p.His433=)	4221	MEN1	Benign	540012	RCV000153486\|RCV000860148;	N	MedGen:CN169374\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572557	64572557	11:g.64572557A>G	ClinGen:CA060368	CN169374 not specified;
NM_001370259.2(MEN1):c.1299= (p.His433=)	4221	MEN1	Benign	540012	RCV001082521\|RCV001812213;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900	11	64572557	64572557	NC_000011.9:g.64572557%3D	ClinGen:CA349916	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1297C>T (p.His433Tyr)	4221	MEN1	Uncertain significance	1941611706	RCV001037159;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572559	64572559	11:g.64572559G>A	-
NM_001370259.2(MEN1):c.1296G>A (p.Leu432=)	4221	MEN1	Conflicting interpretations of pathogenicity	138770431	RCV000030197\|RCV000353672\|RCV000379404\|RCV000492032\|RCV000679247;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|Human Phenotype Ontology:HP:0000843,MONDO:MONDO:0001741,MedGen:C0020502\|MedGen:CN169374\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	11	64572560	64572560	11:g.64572560C>T	ClinGen:CA009109	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1287G>T (p.Thr429=)	4221	MEN1	Likely benign	376598079	RCV000232959\|RCV002379027;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572569	64572569	NC_000011.9:g.64572569C>A	ClinGen:CA060358	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1287G>A (p.Thr429=)	4221	MEN1	Likely benign	376598079	RCV000535325\|RCV001010767;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572569	64572569	11:g.64572569C>T	ClinGen:CA060353	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1286C>T (p.Thr429Met)	4221	MEN1	Uncertain significance	757803925	RCV001971785\|RCV002386848;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572570	64572570	64572570	-
NM_001370259.2(MEN1):c.1279_1282dup (p.Pro428fs)	4221	MEN1	Pathogenic	2136101131	RCV001812583\|RCV001869478;	N	MedGen:C3661900\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572573	64572574	64572573	-
NM_001370259.2(MEN1):c.1281T>A (p.Ser427Arg)	4221	MEN1	Likely pathogenic	1114167528	RCV000491702\|RCV001002226;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572575	64572575	11:g.64572575A>T	ClinGen:CA381180331	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1279A>C (p.Ser427Arg)	4221	MEN1	Conflicting interpretations of pathogenicity	1555164245	RCV000527282\|RCV002377016;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572577	64572577	11:g.64572577T>G	ClinGen:CA381180344	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1271AGG[1] (p.Glu425del)	4221	MEN1	Pathogenic/Likely pathogenic	2136101303	RCV001379321\|RCV002225831;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900	11	64572580	64572582	64572579	-
NM_001370259.2(MEN1):c.1275G>A (p.Glu425=)	4221	MEN1	Likely benign	1236745071	RCV002170053\|RCV003161362;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572581	64572581	64572581	-
NM_001370259.2(MEN1):c.1270G>A (p.Glu424Lys)	4221	MEN1	Uncertain significance	1114167477	RCV000491730\|RCV001344440;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572586	64572586	NC_000011.9:g.64572586C>T	ClinGen:CA381180402	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1268G>A (p.Trp423Ter)	4221	MEN1	Pathogenic	-1	RCV002481160\|RCV002574715;	N	MedGen:CN517202\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572588	64572588	NC_000011.9:g.64572588C>T	-
NM_001370259.2(MEN1):c.1267T>C (p.Trp423Arg)	4221	MEN1	Likely pathogenic	1555164270	RCV000547991\|RCV002377015;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572589	64572589	11:g.64572589A>G	ClinGen:CA381180426	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1266del (p.Lys422fs)	4221	MEN1	Pathogenic/Likely pathogenic	2136101566	RCV001972735\|RCV002256873;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572590	64572590	64572589	-
NM_001370259.2(MEN1):c.1262G>A (p.Cys421Tyr)	4221	MEN1	Pathogenic/Likely pathogenic	386134249	RCV000030196\|RCV000182419\|RCV000491986;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572594	64572594	NC_000011.9:g.64572594C>T	ClinGen:CA009105,UniProtKB:O00255#VAR_039638	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1257C>T (p.Gly419=)	4221	MEN1	Uncertain significance	-1	RCV002866559;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572599	64572599		-
NM_001370259.2(MEN1):c.1253_1256del (p.Asp418fs)	4221	MEN1	Pathogenic	1592637081	RCV000821590;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572600	64572603	11:g.64572600_64572603del	-
NM_001370259.2(MEN1):c.1256G>T (p.Gly419Val)	4221	MEN1	Likely pathogenic	1941615895	RCV001036366;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572600	64572600	11:g.64572600C>A	-
NM_001370259.2(MEN1):c.1255G>A (p.Gly419Ser)	4221	MEN1	Uncertain significance	-1	RCV003090654\|RCV003161721\|RCV003410069;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	11	64572601	64572601	NC_000011.9:g.64572601C>T	-
NM_001370259.2(MEN1):c.1254C>T (p.Asp418=)	4221	MEN1	Benign	2071313	RCV000082332\|RCV000318798\|RCV000491125\|RCV000999731\|RCV001711261;	N	MedGen:CN169374\|Human Phenotype Ontology:HP:0000843,MONDO:MONDO:0001741,MedGen:C0020502\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900	11	64572602	64572602	11:g.64572602G>A	ClinGen:CA009098	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1247_1254del (p.Phe416fs)	4221	MEN1	Pathogenic/Likely pathogenic	1114167542	RCV000491544\|RCV003476178;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572602	64572609	11:g.64572602_64572609del	ClinGen:CA645369505	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1254C>G (p.Asp418Glu)	4221	MEN1	Uncertain significance	2071313	RCV000819849;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572602	64572602	11:g.64572602G>C	-
NM_001370259.2(MEN1):c.1252G>A (p.Asp418Asn)	4221	MEN1	Pathogenic	104894264	RCV000018183\|RCV000490854\|RCV001269702;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	11	64572604	64572604	11:g.64572604C>T	ClinGen:CA009084,UniProtKB:O00255#VAR_005461,OMIM:613733.0027	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1252G>C (p.Asp418His)	4221	MEN1	Pathogenic	104894264	RCV000182455\|RCV001044491;	N	MedGen:CN517202\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572604	64572604	NC_000011.9:g.64572604C>G	ClinGen:CA009091	CN517202 not provided;
NM_001370259.2(MEN1):c.1251C>T (p.Tyr417=)	4221	MEN1	Likely benign	751481164	RCV000632167\|RCV002413804;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572605	64572605	11:g.64572605G>A	ClinGen:CA060323	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1248C>T (p.Phe416=)	4221	MEN1	Likely benign	-1	RCV002871177;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572608	64572608		-
NM_001370259.2(MEN1):c.1244G>C (p.Arg415Pro)	4221	MEN1	Conflicting interpretations of pathogenicity	1446518998	RCV000632109\|RCV003148811;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:CN517202	11	64572612	64572612	NC_000011.9:g.64572612C>G	ClinGen:CA381180568	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1244G>A (p.Arg415Gln)	4221	MEN1	Uncertain significance	1446518998	RCV000632082\|RCV003162804;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572612	64572612	11:g.64572612C>T	ClinGen:CA381180571	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1243C>T (p.Arg415Ter)	4221	MEN1	Pathogenic	1060499974	RCV000456454\|RCV000486722\|RCV000491295;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572613	64572613	NC_000011.9:g.64572613G>A	ClinGen:CA16613380	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1234C>T (p.His412Tyr)	4221	MEN1	Uncertain significance	-1	RCV002662920;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572622	64572622	NC_000011.9:g.64572622G>A	-
NM_001370259.2(MEN1):c.1234del (p.His412fs)	4221	MEN1	Pathogenic	-1	RCV003029269;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572622	64572622	NC_000011.9:g.64572624del	-
NM_001370259.2(MEN1):c.1233C>T (p.Ala411=)	4221	MEN1	Likely benign	-1	RCV003045673\|RCV003308440;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572623	64572623		-
NM_001370259.2(MEN1):c.1231G>T (p.Ala411Ser)	4221	MEN1	Uncertain significance	757179911	RCV000196723\|RCV002363020\|RCV003151755;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	11	64572625	64572625	NC_000011.9:g.64572625C>A	ClinGen:CA336654	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1231G>A (p.Ala411Thr)	4221	MEN1	Uncertain significance	757179911	RCV000559474\|RCV003159746;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MeSH:D030342,MedGen:C0950123	11	64572625	64572625	NC_000011.9:g.64572625C>T	ClinGen:CA060315	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1231G>C (p.Ala411Pro)	4221	MEN1	Likely pathogenic	-1	RCV003062404;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572625	64572625	NC_000011.9:g.64572625C>G	-
NM_001370259.2(MEN1):c.1230C>T (p.Phe410=)	4221	MEN1	Likely benign	878855188	RCV000227264\|RCV000566957;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572626	64572626	NC_000011.9:g.64572626G>A	ClinGen:CA10582931	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1230del (p.Phe410fs)	4221	MEN1	Likely pathogenic	-1	RCV003233049;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572626	64572626		-
NM_001370259.2(MEN1):c.1226G>A (p.Cys409Tyr)	4221	MEN1	Uncertain significance	1060499988	RCV000466185\|RCV001010429;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572630	64572630	NC_000011.9:g.64572630C>T	ClinGen:CA16613671	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1224_1225insGTCC (p.Cys409fs)	4221	MEN1	Pathogenic	1114167524	RCV000491151\|RCV000546948;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572631	64572632	11:g.64572631_64572632insGGAC	ClinGen:CA645369506	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1222G>C (p.Glu408Gln)	4221	MEN1	Uncertain significance	1941620661	RCV001211418;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572634	64572634	11:g.64572634C>G	-
NM_001370259.2(MEN1):c.1221dup (p.Glu408Ter)	4221	MEN1	Pathogenic	2136102861	RCV001948215;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572634	64572635	64572634	-
NM_001370259.2(MEN1):c.1220_1221del (p.Pro407fs)	4221	MEN1	Pathogenic	1592637440	RCV000806985\|RCV003148867;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:CN517202	11	64572635	64572636	11:g.64572635_64572636del	-
NM_001370259.2(MEN1):c.1219_1220del (p.Asp406_Pro407insTer)	4221	MEN1	Pathogenic	1592637455	RCV000803877;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572636	64572637	11:g.64572636_64572637del	-
NM_001370259.2(MEN1):c.1219C>G (p.Pro407Ala)	4221	MEN1	Uncertain significance	1060499985	RCV000457365\|RCV003380567;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572637	64572637	NC_000011.9:g.64572637G>C	ClinGen:CA16613461	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1214dup (p.Asp406fs)	4221	MEN1	Pathogenic	1114167513	RCV000491633\|RCV001390120;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572641	64572642	11:g.64572641_64572642insT	ClinGen:CA645369507	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1215G>A (p.Gln405=)	4221	MEN1	Uncertain significance	1289898067	RCV001053857;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572641	64572641	11:g.64572641C>T	-
NM_001370259.2(MEN1):c.1213C>T (p.Gln405Ter)	4221	MEN1	Pathogenic	864622615	RCV000205609\|RCV000256143\|RCV000506315\|RCV002354582;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900\|MedGen:CN169374\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572643	64572643	NC_000011.9:g.64572643G>A	ClinGen:CA349734	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1212C>G (p.Leu404=)	4221	MEN1	Benign/Likely benign	577268289	RCV000632166\|RCV001010344\|RCV003233032;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0054601,MedGen:C4539685,OMIM:617540	11	64572644	64572644	NC_000011.9:g.64572644G>C	ClinGen:CA060309	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1212C>T (p.Leu404=)	4221	MEN1	Likely benign	-1	RCV002871718;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572644	64572644		-
NM_001370259.2(MEN1):c.1211T>A (p.Leu404His)	4221	MEN1	Uncertain significance	1941623255	RCV001215096;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572645	64572645	11:g.64572645A>T	-
NM_001370259.2(MEN1):c.1210C>T (p.Leu404Phe)	4221	MEN1	Uncertain significance	1060499989	RCV000472387;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572646	64572646	NC_000011.9:g.64572646G>A	ClinGen:CA16613462	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1207G>A (p.Ala403Thr)	4221	MEN1	Uncertain significance	746135199	RCV000632136\|RCV002343215;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572649	64572649	NC_000011.9:g.64572649C>T	ClinGen:CA060300	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1206C>T (p.Ser402=)	4221	MEN1	Likely benign	770037856	RCV000460839\|RCV001010304;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572650	64572650	NC_000011.9:g.64572650G>A	ClinGen:CA060291	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1206C>A (p.Ser402=)	4221	MEN1	Likely benign	770037856	RCV000632148\|RCV001080450\|RCV002343216;	N	MedGen:C3661900\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572650	64572650	11:g.64572650G>T	ClinGen:CA060283	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1206del (p.Ala403fs)	4221	MEN1	Pathogenic	1941624571	RCV001227911;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572650	64572650	11:g.64572650_64572650del	-
NM_001370259.2(MEN1):c.1203T>C (p.Gly401=)	4221	MEN1	Likely benign	878855187	RCV000233483\|RCV003165649;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572653	64572653	NC_000011.9:g.64572653A>G	ClinGen:CA10582932	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1202G>T (p.Gly401Val)	4221	MEN1	Uncertain significance	878855186	RCV000229429\|RCV002347916;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572654	64572654	NC_000011.9:g.64572654C>A	ClinGen:CA10582933	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1202del (p.Gly401fs)	4221	MEN1	Pathogenic	1941625647	RCV001037823\|RCV002346250;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572654	64572654	11:g.64572654_64572654del	-
NM_001370259.2(MEN1):c.1198C>T (p.Gln400Ter)	4221	MEN1	Pathogenic	886039419	RCV000255350\|RCV001198769;	N	MedGen:CN517202\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572658	64572658	11:g.64572658G>A	ClinGen:CA10588528	CN517202 not provided;
NM_001370259.2(MEN1):c.1198C>A (p.Gln400Lys)	4221	MEN1	Uncertain significance	886039419	RCV001339158;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572658	64572658	64572658	-
NM_001370259.2(MEN1):c.1195A>G (p.Ser399Gly)	4221	MEN1	Uncertain significance	1941626700	RCV001308298\|RCV002341617;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572661	64572661	64572661	-
NM_001370259.2(MEN1):c.1193dup (p.Ser399fs)	4221	MEN1	Pathogenic	1555164430	RCV000632080;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572662	64572663	NC_000011.9:g.64572663dup	ClinGen:CA658797667	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1194G>C (p.Gln398His)	4221	MEN1	Uncertain significance	1592637824	RCV000806343;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572662	64572662	11:g.64572662C>G	-
NM_001370259.2(MEN1):c.1192C>G (p.Gln398Glu)	4221	MEN1	Uncertain significance	886039418	RCV001010268\|RCV001342349;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572664	64572664	11:g.64572664G>C	-
NM_001370259.2(MEN1):c.1191C>T (p.Thr397=)	4221	MEN1	Likely benign	1166154585	RCV001479991\|RCV003159745;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572665	64572665	11:g.64572665G>A	ClinGen:CA474982950	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1190C>T (p.Thr397Ile)	4221	MEN1	Uncertain significance	1941628720	RCV001310029\|RCV003416184;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|	11	64572666	64572666	64572666	-
NM_001370259.2(MEN1):c.1186-5T>C	4221	MEN1	Likely benign	1941629779	RCV001483474;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572675	64572675	64572675	-
NM_001370259.2(MEN1):c.1186-6G>A	4221	MEN1	Likely benign	576193460	RCV000504111\|RCV001082032\|RCV002255399;	N	MedGen:CN169374\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64572676	64572676	NC_000011.9:g.64572676C>T	ClinGen:CA060265	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1186-7C>T	4221	MEN1	Likely benign	587780842	RCV000123381;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572677	64572677	NC_000011.9:g.64572677G>A	ClinGen:CA009074	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1186-7C>G	4221	MEN1	Likely benign	587780842	RCV001433482;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572677	64572677	64572677	-
NM_001370259.2(MEN1):c.1186-8del	4221	MEN1	Likely benign	1555164452	RCV000558432;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572678	64572678	11:g.64572678_64572678del	ClinGen:CA658656144	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1186-9C>T	4221	MEN1	Likely benign	1555164455	RCV000632160;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572679	64572679	11:g.64572679G>A	ClinGen:CA658797668	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1186-10C>T	4221	MEN1	Conflicting interpretations of pathogenicity	762303621	RCV000264959\|RCV000375854;	N	Human Phenotype Ontology:HP:0000843,MONDO:MONDO:0001741,MedGen:C0020502\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572680	64572680	11:g.64572680G>A	ClinGen:CA10639643	C0020502 Hyperparathyroidism;
NM_001370259.2(MEN1):c.1186-13C>T	4221	MEN1	Likely benign	1181170442	RCV002190855;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572683	64572683	64572683	-
NM_001370259.2(MEN1):c.1186-14T>C	4221	MEN1	Likely benign	-1	RCV002886013;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572684	64572684	NC_000011.9:g.64572684A>G	-
NM_001370259.2(MEN1):c.1186-15T>A	4221	MEN1	Likely benign	1482248002	RCV002123886;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572685	64572685	64572685	-
NM_001370259.2(MEN1):c.1186-16C>T	4221	MEN1	Likely benign	-1	RCV003073422;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572686	64572686	NC_000011.9:g.64572686G>A	-
NM_001370259.2(MEN1):c.1186-17C>T	4221	MEN1	Likely benign	773542607	RCV002118890;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64572687	64572687	64572687	-
NM_001370259.2(MEN1):c.1185+19A>G	4221	MEN1	Likely benign	1456615213	RCV002084325;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573088	64573088	64573088	-
NM_001370259.2(MEN1):c.1185+18C>A	4221	MEN1	Likely benign	780329058	RCV002178367;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573089	64573089	64573089	-
NM_001370259.2(MEN1):c.1185+18C>T	4221	MEN1	Conflicting interpretations of pathogenicity	780329058	RCV002123811\|RCV002337347;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573089	64573089	64573089	-
NM_001370259.2(MEN1):c.1185+15C>G	4221	MEN1	Likely benign	2136107680	RCV002151076;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573092	64573092	64573092	-
NM_001370259.2(MEN1):c.1185+13A>G	4221	MEN1	Likely benign	-1	RCV003033015;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573094	64573094	NC_000011.9:g.64573094T>C	-
NM_001370259.2(MEN1):c.1185+12G>A	4221	MEN1	Conflicting interpretations of pathogenicity	373609932	RCV000209727\|RCV000608324\|RCV001529469\|RCV001762454;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN169374\|MedGen:C3661900\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573095	64573095	11:g.64573095C>T	ClinGen:CA060120	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1185+12G>C	4221	MEN1	Likely benign	373609932	RCV002172824;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573095	64573095	64573095	-
NM_001370259.2(MEN1):c.1185+10dup	4221	MEN1	Likely benign	2136107816	RCV002219872;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573096	64573097	64573096	-
NC_000011.9:g.(?_64573097)_(64575581_?)del	4221	MEN1	Pathogenic	-1	RCV003123029;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573097	64575581		-
NM_001370259.2(MEN1):c.1185+6A>G	4221	MEN1	Uncertain significance	2136107870	RCV001973727;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573101	64573101	64573101	-
NM_001370259.2(MEN1):c.1185+5A>G	4221	MEN1	Conflicting interpretations of pathogenicity	748700116	RCV000696574\|RCV002334322;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573102	64573102	NC_000011.9:g.64573102T>C	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1185+4A>G	4221	MEN1	Uncertain significance	863224809	RCV000200321\|RCV002336545\|RCV003407711;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|	11	64573103	64573103	11:g.64573103T>C	ClinGen:CA339242	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1185+3G>A	4221	MEN1	Uncertain significance	1199137996	RCV001303240;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573104	64573104	64573104	-
NM_001370259.2(MEN1):c.1185+1G>A	4221	MEN1	Uncertain significance	1941661315	RCV001253238;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573106	64573106	11:g.64573106C>T	-
NM_001370259.2(MEN1):c.1182C>T (p.Ser394=)	4221	MEN1	Likely benign	1396452284	RCV000976292\|RCV002327199;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573110	64573110	11:g.64573110G>A	-
NM_001370259.2(MEN1):c.1181G>C (p.Ser394Thr)	4221	MEN1	Uncertain significance	934222398	RCV000472591;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573111	64573111	NC_000011.9:g.64573111C>G	ClinGen:CA16613381	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1177C>G (p.Gln393Glu)	4221	MEN1	Uncertain significance	1060499984	RCV000472220\|RCV000708704;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573115	64573115	NC_000011.9:g.64573115G>C	ClinGen:CA16613386	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1177C>T (p.Gln393Ter)	4221	MEN1	Pathogenic	1060499984	RCV000491380\|RCV001203901;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573115	64573115	NC_000011.9:g.64573115G>A	ClinGen:CA381182053	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1174dup (p.Glu392fs)	4221	MEN1	Likely pathogenic	386134247	RCV000030194;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573117	64573118	11:g.64573117_64573118insC	ClinGen:CA260440	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1174del (p.Glu392fs)	4221	MEN1	Pathogenic/Likely pathogenic	386134247	RCV000255795\|RCV000714231;	N	MedGen:CN517202\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573118	64573118	11:g.64573118_64573118del	ClinGen:CA10588530	CN517202 not provided;
NM_001370259.2(MEN1):c.1174G>T (p.Glu392Ter)	4221	MEN1	Pathogenic	772588551	RCV000476658\|RCV000523599\|RCV002329011;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573118	64573118	NC_000011.9:g.64573118C>A	ClinGen:CA16613679	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1173G>A (p.Gly391=)	4221	MEN1	Likely benign	1592639850	RCV001417535;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573119	64573119	11:g.64573119C>T	-
NM_001370259.2(MEN1):c.1172G>A (p.Gly391Glu)	4221	MEN1	Uncertain significance	998827212	RCV001300942\|RCV002327650;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573120	64573120	64573120	-
NM_001370259.2(MEN1):c.1170G>C (p.Pro390=)	4221	MEN1	Likely benign	587780841	RCV000123380\|RCV000562906;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573122	64573122	NC_000011.9:g.64573122C>G	ClinGen:CA009055	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1170G>A (p.Pro390=)	4221	MEN1	Benign/Likely benign	587780841	RCV000199870\|RCV000569118\|RCV000729820\|RCV001706182;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN169374\|MedGen:C3661900	11	64573122	64573122	NC_000011.9:g.64573122C>T	ClinGen:CA060100	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1170G>T (p.Pro390=)	4221	MEN1	Likely benign	587780841	RCV001504846\|RCV002329639;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573122	64573122	64573122	-
NM_001370259.2(MEN1):c.1169C>T (p.Pro390Leu)	4221	MEN1	Conflicting interpretations of pathogenicity	761102084	RCV000457486\|RCV000568225\|RCV000994656\|RCV001821219;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900\|MedGen:CN169374	11	64573123	64573123	11:g.64573123G>A	ClinGen:CA060092	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1169C>G (p.Pro390Arg)	4221	MEN1	Uncertain significance	761102084	RCV000632078;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573123	64573123	NC_000011.9:g.64573123G>C	ClinGen:CA060079	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1169C>A (p.Pro390Gln)	4221	MEN1	Uncertain significance	761102084	RCV001867307;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573123	64573123	64573123	-
NM_001370259.2(MEN1):c.1167G>C (p.Arg389=)	4221	MEN1	Likely benign	1194388602	RCV000546169\|RCV003380599;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573125	64573125	11:g.64573125C>G	ClinGen:CA474983082	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1166G>A (p.Arg389Gln)	4221	MEN1	Conflicting interpretations of pathogenicity	775267651	RCV000203887\|RCV001017497;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573126	64573126	NC_000011.9:g.64573126C>T	ClinGen:CA060070	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1166G>C (p.Arg389Pro)	4221	MEN1	Uncertain significance	775267651	RCV000800804\|RCV001017498;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573126	64573126	11:g.64573126C>G	-
NM_001370259.2(MEN1):c.1165C>T (p.Arg389Trp)	4221	MEN1	Conflicting interpretations of pathogenicity	566593066	RCV000463517\|RCV001017493;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573127	64573127	NC_000011.9:g.64573127G>A	ClinGen:CA16613614	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1163A>G (p.Glu388Gly)	4221	MEN1	Uncertain significance	-1	RCV002321387\|RCV003094501;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573129	64573129	64573129	-
NM_001370259.2(MEN1):c.1159G>A (p.Glu387Lys)	4221	MEN1	Uncertain significance	773978650	RCV000467350\|RCV002374736;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573133	64573133	NC_000011.9:g.64573133C>T	ClinGen:CA060044	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1158C>T (p.Gly386=)	4221	MEN1	Uncertain significance	794728653	RCV000457527\|RCV001010040;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573134	64573134	NC_000011.9:g.64573134G>A	ClinGen:CA009049	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1158C>G (p.Gly386=)	4221	MEN1	Likely benign	794728653	RCV001401970;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573134	64573134	11:g.64573134G>C	-
NM_001370259.2(MEN1):c.1158C>A (p.Gly386=)	4221	MEN1	Likely benign	794728653	RCV001506908;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573134	64573134	64573134	-
NM_001370259.2(MEN1):c.1157G>A (p.Gly386Asp)	4221	MEN1	Conflicting interpretations of pathogenicity	761360623	RCV000204534\|RCV000570220;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573135	64573135	NC_000011.9:g.64573135C>T	ClinGen:CA060027	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1157G>C (p.Gly386Ala)	4221	MEN1	Uncertain significance	761360623	RCV001947742\|RCV002361232;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573135	64573135	64573135	-
NM_001370259.2(MEN1):c.1156G>A (p.Gly386Ser)	4221	MEN1	Uncertain significance	767595183	RCV001216689\|RCV002365975;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573136	64573136	11:g.64573136C>T	-
NM_001370259.2(MEN1):c.1155G>A (p.Ala385=)	4221	MEN1	Likely benign	201091135	RCV000198409\|RCV000561075\|RCV001675667;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	11	64573137	64573137	NC_000011.9:g.64573137C>T	ClinGen:CA060010	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1155G>T (p.Ala385=)	4221	MEN1	Likely benign	201091135	RCV001401226;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573137	64573137	64573137	-
NM_001370259.2(MEN1):c.1154C>T (p.Ala385Val)	4221	MEN1	Conflicting interpretations of pathogenicity	1298484645	RCV000632086\|RCV001010012\|RCV001703217;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	11	64573138	64573138	NC_000011.9:g.64573138G>A	ClinGen:CA381182214	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1149G>A (p.Leu383=)	4221	MEN1	Likely benign	1555164667	RCV000632153\|RCV002460097;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573143	64573143	NC_000011.9:g.64573143C>T	ClinGen:CA474983096	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1147C>T (p.Leu383=)	4221	MEN1	Likely benign	2136109092	RCV001495679\|RCV002456886;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573145	64573145	64573145	-
NM_001370259.2(MEN1):c.1144T>C (p.Leu382=)	4221	MEN1	Likely benign	2136109118	RCV002156364;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573148	64573148	64573148	-
NM_001370259.2(MEN1):c.1139C>G (p.Ala380Gly)	4221	MEN1	Uncertain significance	1565642307	RCV000695794;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573153	64573153	NC_000011.9:g.64573153G>C	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1138G>A (p.Ala380Thr)	4221	MEN1	Uncertain significance	1225964479	RCV001201836\|RCV002322000;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573154	64573154	11:g.64573154C>T	-
NM_001370259.2(MEN1):c.1136dup (p.Ala380fs)	4221	MEN1	Pathogenic	1592640181	RCV001002347;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573155	64573156	11:g.64573155_64573156insG	-
NM_001370259.2(MEN1):c.1137A>C (p.Ala379=)	4221	MEN1	Likely benign	2136109300	RCV002185287;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573155	64573155	64573155	-
NM_001370259.2(MEN1):c.1136C>A (p.Ala379Glu)	4221	MEN1	Uncertain significance	1592640172	RCV001009941\|RCV001215725;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573156	64573156	11:g.64573156G>T	-
NM_001370259.2(MEN1):c.1135G>A (p.Ala379Thr)	4221	MEN1	Uncertain significance	2136109409	RCV002002685;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573157	64573157	64573157	-
NM_001370259.2(MEN1):c.1131G>A (p.Lys377=)	4221	MEN1	Likely benign	1555164674	RCV000632175;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573161	64573161	NC_000011.9:g.64573161C>T	ClinGen:CA474983108	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1130A>G (p.Lys377Arg)	4221	MEN1	Uncertain significance	766075737	RCV000632138\|RCV003162805;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573162	64573162	NC_000011.9:g.64573162T>C	ClinGen:CA059992	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1128G>A (p.Leu376=)	4221	MEN1	Likely benign	754129242	RCV000911187\|RCV001017414;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573164	64573164	11:g.64573164C>T	-
NM_001370259.2(MEN1):c.1126C>A (p.Leu376Met)	4221	MEN1	Uncertain significance	-1	RCV003470100;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573166	64573166		-
NM_001370259.2(MEN1):c.1125G>C (p.Leu375=)	4221	MEN1	Likely benign	867481093	RCV002193460;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573167	64573167	64573167	-
NM_001370259.2(MEN1):c.1125G>A (p.Leu375=)	4221	MEN1	Likely benign	867481093	RCV002140184\|RCV002434564;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573167	64573167	64573167	-
NM_001370259.2(MEN1):c.1124T>A (p.Leu375Gln)	4221	MEN1	Uncertain significance	1941668371	RCV001234170;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573168	64573168	11:g.64573168A>T	-
NM_001370259.2(MEN1):c.1123C>G (p.Leu375Val)	4221	MEN1	Uncertain significance	1211957325	RCV000575830\|RCV000632112;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573169	64573169	NC_000011.9:g.64573169G>C	ClinGen:CA381182444	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1121A>G (p.Asn374Ser)	4221	MEN1	Conflicting interpretations of pathogenicity	755168633	RCV001317315\|RCV003166824;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573171	64573171	64573171	-
NM_001370259.2(MEN1):c.1121A>C (p.Asn374Thr)	4221	MEN1	Uncertain significance	-1	RCV002440066\|RCV003465767;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573171	64573171	64573171	-
NM_001370259.2(MEN1):c.1119C>T (p.Pro373=)	4221	MEN1	Likely benign	535417698	RCV001402305\|RCV002434127;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573173	64573173	11:g.64573173G>A	-
NM_001370259.2(MEN1):c.1119C>A (p.Pro373=)	4221	MEN1	Likely benign	535417698	RCV000877414\|RCV001009910;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573173	64573173	11:g.64573173G>T	-
NM_001370259.2(MEN1):c.1119del (p.Asn374fs)	4221	MEN1	Pathogenic	-1	RCV002795935;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573173	64573173	NC_000011.9:g.64573176del	-
NM_001370259.2(MEN1):c.1117C>T (p.Pro373Ser)	4221	MEN1	Likely pathogenic	794728627	RCV000709158;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573175	64573175	11:g.64573175G>A	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1117C>A (p.Pro373Thr)	4221	MEN1	Uncertain significance	794728627	RCV001951636;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573175	64573175	64573175	-
NM_001370259.2(MEN1):c.1111G>A (p.Val371Ile)	4221	MEN1	Uncertain significance	1941669758	RCV001317008\|RCV003166821;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573181	64573181	64573181	-
NM_001370259.2(MEN1):c.1106A>G (p.Asn369Ser)	4221	MEN1	Uncertain significance	1368034727	RCV001216536;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573186	64573186	11:g.64573186T>C	-
NM_001370259.2(MEN1):c.1104C>A (p.Ala368=)	4221	MEN1	Likely benign	-1	RCV002865984;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573188	64573188		-
NM_001370259.2(MEN1):c.1103C>A (p.Ala368Asp)	4221	MEN1	Pathogenic	1555164707	RCV000659846;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573189	64573189	11:g.64573189G>T	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1102del (p.Ala368fs)	4221	MEN1	Likely pathogenic	2136110242	RCV001532962;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573190	64573190	64573189	-
NM_001370259.2(MEN1):c.1100T>C (p.Val367Ala)	4221	MEN1	Uncertain significance	2136110269	RCV001969587;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573192	64573192	64573192	-
NM_001370259.2(MEN1):c.1099G>A (p.Val367Ile)	4221	MEN1	Conflicting interpretations of pathogenicity	758404089	RCV000456726\|RCV000569841\|RCV001289028;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	11	64573193	64573193	NC_000011.9:g.64573193C>T	ClinGen:CA059937	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1098A>T (p.Glu366Asp)	4221	MEN1	Conflicting interpretations of pathogenicity	149383809	RCV000161928\|RCV000567306\|RCV002267897;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN169374	11	64573194	64573194	NC_000011.9:g.64573194T>A	ClinGen:CA009023	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1095T>C (p.Phe365=)	4221	MEN1	Likely benign	1592640464	RCV001487089;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573197	64573197	11:g.64573197A>G	-
NM_001370259.2(MEN1):c.1093T>C (p.Phe365Leu)	4221	MEN1	Uncertain significance	1592640479	RCV000813316;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573199	64573199	11:g.64573199A>G	-
NM_001370259.2(MEN1):c.1092C>A (p.Phe364Leu)	4221	MEN1	Uncertain significance	863224808	RCV000196551;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573200	64573200	NC_000011.9:g.64573200G>T	ClinGen:CA336516	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1087_1089del (p.Glu363del)	4221	MEN1	Pathogenic	869025185	RCV000018165\|RCV000255250\|RCV000491660;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573203	64573205	NC_000011.9:g.64573205_64573207del	OMIM:613733.0009,ClinGen:CA356504	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1089G>A (p.Glu363=)	4221	MEN1	Likely benign	2136110455	RCV002086318;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573203	64573203	64573203	-
NM_001370259.2(MEN1):c.1089G>C (p.Glu363Asp)	4221	MEN1	Uncertain significance	-1	RCV002443694\|RCV003098757;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573203	64573203	64573203	-
NM_001370259.2(MEN1):c.1086G>A (p.Lys362=)	4221	MEN1	Likely benign	1941672084	RCV001506770\|RCV002424948;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573206	64573206	64573206	-
NM_001370259.2(MEN1):c.1084A>G (p.Lys362Glu)	4221	MEN1	Uncertain significance	1941672276	RCV001300659;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573208	64573208	64573208	-
NM_001370259.2(MEN1):c.1083C>T (p.Tyr361=)	4221	MEN1	Likely benign	1168237114	RCV000632151\|RCV002431866;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573209	64573209	NC_000011.9:g.64573209G>A	ClinGen:CA474983144	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1080C>T (p.Ile360=)	4221	MEN1	Likely benign	147331514	RCV000506264\|RCV000574517\|RCV000988572\|RCV001529229;	N	MedGen:CN169374\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900	11	64573212	64573212	NC_000011.9:g.64573212G>A	ClinGen:CA059924	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1072GAG[1] (p.Glu359del)	4221	MEN1	Conflicting interpretations of pathogenicity	1060499971	RCV000463375;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573215	64573217	NC_000011.9:g.64573215CTC[1]	ClinGen:CA16613681	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1077G>T (p.Glu359Asp)	4221	MEN1	Uncertain significance	-1	RCV002299860;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573215	64573215	64573215	-
NM_001370259.2(MEN1):c.1076A>C (p.Glu359Ala)	4221	MEN1	Uncertain significance	-1	RCV002297211;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573216	64573216	64573216	-
NM_001370259.2(MEN1):c.1074G>A (p.Glu358=)	4221	MEN1	Likely benign	776834299	RCV001431346\|RCV002418428;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573218	64573218	NC_000011.9:g.64573218C>T	ClinGen:CA059916	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1072G>A (p.Glu358Lys)	4221	MEN1	Uncertain significance	1941674204	RCV001924228;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573220	64573220	64573220	-
NM_001370259.2(MEN1):c.1071C>T (p.Asp357=)	4221	MEN1	Likely benign	371964966	RCV000465120\|RCV000572706;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573221	64573221	NC_000011.9:g.64573221G>A	ClinGen:CA059908	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1069G>A (p.Asp357Asn)	4221	MEN1	Uncertain significance	768448073	RCV000793965;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573223	64573223	11:g.64573223C>T	-
NM_001370259.2(MEN1):c.1065G>C (p.Arg355=)	4221	MEN1	Likely benign	1592640719	RCV001443114\|RCV002409207;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573227	64573227	11:g.64573227C>G	-
NM_001370259.2(MEN1):c.1065G>T (p.Arg355=)	4221	MEN1	Likely benign	1592640719	RCV001482936\|RCV002414171;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573227	64573227	64573227	-
NM_001370259.2(MEN1):c.1064G>A (p.Arg355Gln)	4221	MEN1	Conflicting interpretations of pathogenicity	1114167474	RCV000491631\|RCV000761778\|RCV000797646;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573228	64573228	NC_000011.9:g.64573228C>T	ClinGen:CA381182908	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1063del (p.Arg355fs)	4221	MEN1	Likely pathogenic	386134246	RCV000030193;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573229	64573229	11:g.64573229_64573229del	ClinGen:CA009011	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1063C>A (p.Arg355=)	4221	MEN1	Uncertain significance	863224807	RCV000200097;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573229	64573229	NC_000011.9:g.64573229G>T	ClinGen:CA339093	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1063C>T (p.Arg355Trp)	4221	MEN1	Uncertain significance	863224807	RCV000632081\|RCV001009797;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573229	64573229	NC_000011.9:g.64573229G>A	ClinGen:CA381182913	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1063C>G (p.Arg355Gly)	4221	MEN1	Uncertain significance	863224807	RCV001204111;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573229	64573229	11:g.64573229G>C	-
NM_001370259.2(MEN1):c.1062C>A (p.Cys354Ter)	4221	MEN1	Pathogenic	104894265	RCV000018185;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573230	64573230	11:g.64573230G>T	ClinGen:CA009004,OMIM:613733.0029	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1062C>T (p.Cys354=)	4221	MEN1	Likely benign	104894265	RCV001436365;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573230	64573230	11:g.64573230G>A	-
NM_001370259.2(MEN1):c.1061G>A (p.Cys354Tyr)	4221	MEN1	Uncertain significance	904261642	RCV000551988\|RCV002413455;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573231	64573231	11:g.64573231C>T	ClinGen:CA381182936	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1061G>T (p.Cys354Phe)	4221	MEN1	Uncertain significance	904261642	RCV001896509\|RCV002407013;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573231	64573231	64573231	-
NM_001370259.2(MEN1):c.1060T>C (p.Cys354Arg)	4221	MEN1	Uncertain significance	371503251	RCV000574233\|RCV000699682;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573232	64573232	11:g.64573232A>G	ClinGen:CA059880	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1059C>T (p.Tyr353=)	4221	MEN1	Likely benign	1592640846	RCV001433291;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573233	64573233	11:g.64573233G>A	-
NM_001370259.2(MEN1):c.1058_1059insTG (p.Cys354fs)	4221	MEN1	Pathogenic	2136111335	RCV001382783;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573233	64573234	64573233	-
NM_001370259.2(MEN1):c.1058A>C (p.Tyr353Ser)	4221	MEN1	Uncertain significance	1592640870	RCV000816807;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573234	64573234	11:g.64573234T>G	-
NM_001370259.2(MEN1):c.1056C>T (p.Asn352=)	4221	MEN1	Likely benign	1565642741	RCV001417821;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573236	64573236	64573236	-
NM_001370259.2(MEN1):c.1055A>G (p.Asn352Ser)	4221	MEN1	Uncertain significance	-1	RCV003461849;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573237	64573237		-
NM_001370259.2(MEN1):c.1050-2A>T	4221	MEN1	Pathogenic	1565642765	RCV000698599;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573244	64573244	NC_000011.9:g.64573244T>A	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1050-2A>G	4221	MEN1	Pathogenic	1565642765	RCV000801108;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573244	64573244	11:g.64573244T>C	-
NM_001370259.2(MEN1):c.1050-3C>T	4221	MEN1	Uncertain significance	2136111597	RCV001927281\|RCV003167001;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573245	64573245	64573245	-
NM_001370259.2(MEN1):c.1050-3C>G	4221	MEN1	Conflicting interpretations of pathogenicity	-1	RCV003225588\|RCV003395729\|RCV003466041;	N	MedGen:C3661900\|\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573245	64573245		-
NM_001370259.2(MEN1):c.1050-7C>T	4221	MEN1	Likely benign	1000294408	RCV001452455;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573249	64573249	64573249	-
NM_001370259.2(MEN1):c.1050-19G>C	4221	MEN1	Likely benign	1322811280	RCV002178274;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573261	64573261	64573261	-
NM_001370259.2(MEN1):c.1050-19G>A	4221	MEN1	Likely benign	-1	RCV002801458;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573261	64573261	NC_000011.9:g.64573261C>T	-
NM_001370259.2(MEN1):c.1050-20A>G	4221	MEN1	Likely benign	2136111796	RCV002214938;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573262	64573262	64573262	-
NM_001370259.2(MEN1):c.623_1050-143del	4221	MEN1	Pathogenic	-1	RCV000822934;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573385	64575394	11:g.64573385_64573483del	-
NM_001370259.2(MEN1):c.940_1050-227del	4221	MEN1	Pathogenic	-1	RCV000556751;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573469	64573813	NC_000011.9:g.64573469_64573813del	ClinGen:CA658656152	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1049+17T>G	4221	MEN1	Likely benign	-1	RCV003066425;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573687	64573687	NC_000011.9:g.64573687A>C	-
NM_001370259.2(MEN1):c.1049+15A>G	4221	MEN1	Likely benign	-1	RCV002770105;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573689	64573689	NC_000011.9:g.64573689T>C	-
NM_001370259.2(MEN1):c.1049+13C>T	4221	MEN1	Likely benign	533537007	RCV001971702;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573691	64573691	64573691	-
NM_001370259.2(MEN1):c.1049+13C>A	4221	MEN1	Likely benign	-1	RCV003048647;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573691	64573691	NC_000011.9:g.64573691G>T	-
NM_001370259.2(MEN1):c.1049+12C>A	4221	MEN1	Likely benign	-1	RCV003070020;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573692	64573692	NC_000011.9:g.64573692G>T	-
NM_001370259.2(MEN1):c.1049+11C>A	4221	MEN1	Likely benign	1229329826	RCV002205950;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573693	64573693	64573693	-
NM_001370259.2(MEN1):c.1049+11C>T	4221	MEN1	Likely benign	-1	RCV002791668;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573693	64573693	NC_000011.9:g.64573693G>A	-
NM_001370259.2(MEN1):c.1049+9C>T	4221	MEN1	Conflicting interpretations of pathogenicity	200517349	RCV000030192\|RCV000609911\|RCV000679246\|RCV001108572\|RCV002255260;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:CN169374\|MedGen:C3661900\|Human Phenotype Ontology:HP:0000843,MONDO:MONDO:0001741,MedGen:C0020502\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573695	64573695	11:g.64573695G>A	ClinGen:CA008998	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1049+9C>A	4221	MEN1	Likely benign	200517349	RCV000457328;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573695	64573695	NC_000011.9:g.64573695G>T	ClinGen:CA16613615	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1049+9C>G	4221	MEN1	Likely benign	200517349	RCV000555401;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573695	64573695	11:g.64573695G>C	ClinGen:CA223914371	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1049+8T>C	4221	MEN1	Likely benign	2136117570	RCV002208069;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573696	64573696	64573696	-
NM_001370259.2(MEN1):c.1049+6G>A	4221	MEN1	Uncertain significance	-1	RCV002658366;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573698	64573698	NC_000011.9:g.64573698C>T	-
NM_001370259.2(MEN1):c.1049+2T>C	4221	MEN1	Likely pathogenic	1555164946	RCV000659845;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573702	64573702	NC_000011.9:g.64573702A>G	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1049+1G>A	4221	MEN1	Pathogenic	1114167489	RCV000632121\|RCV002404747\|RCV003330850;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0017169,MedGen:C0027662,OMIM:PS131100, Orphanet:276161	11	64573703	64573703	NC_000011.9:g.64573703C>T	ClinGen:CA381183128	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1045del (p.Gln349fs)	4221	MEN1	Pathogenic	2136117722	RCV001385000;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573708	64573708	64573707	-
NM_001370259.2(MEN1):c.1045C>T (p.Gln349Ter)	4221	MEN1	Pathogenic	2136117686	RCV002244089;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573708	64573708	64573708	-
NM_001370259.2(MEN1):c.1040T>A (p.Val347Asp)	4221	MEN1	Uncertain significance	1592642971	RCV000799507;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573713	64573713	11:g.64573713A>T	-
NM_001370259.2(MEN1):c.1038T>C (p.Thr346=)	4221	MEN1	Likely benign	1414483292	RCV001462071\|RCV002396090;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573715	64573715	64573715	-
NM_001370259.2(MEN1):c.1036A>G (p.Thr346Ala)	4221	MEN1	Uncertain significance	2136117914	RCV001944757;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573717	64573717	64573717	-
NM_001370259.2(MEN1):c.1036A>T (p.Thr346Ser)	4221	MEN1	Uncertain significance	2136117914	RCV002008636\|RCV003170384;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573717	64573717	64573717	-
NM_001370259.2(MEN1):c.1035C>T (p.Ala345=)	4221	MEN1	Likely benign	-1	RCV002953661;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573718	64573718		-
NM_001370259.2(MEN1):c.1032G>A (p.Thr344=)	4221	MEN1	Likely benign	760183888	RCV000543972\|RCV000562124\|RCV003114656;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	11	64573721	64573721	11:g.64573721C>T	ClinGen:CA059715	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1032G>C (p.Thr344=)	4221	MEN1	Likely benign	760183888	RCV001467684;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573721	64573721	64573721	-
NM_001370259.2(MEN1):c.1031C>T (p.Thr344Met)	4221	MEN1	Uncertain significance	1259681826	RCV000632122\|RCV003380646;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573722	64573722	NC_000011.9:g.64573722G>A	ClinGen:CA381183208	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1031C>G (p.Thr344Arg)	4221	MEN1	Pathogenic	1259681826	RCV001368588;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573722	64573722	64573722	-
NM_001370259.2(MEN1):c.1029C>G (p.Asp343Glu)	4221	MEN1	Uncertain significance	878855185	RCV000226644;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573724	64573724	NC_000011.9:g.64573724G>C	ClinGen:CA10582934	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1027G>A (p.Asp343Asn)	4221	MEN1	Uncertain significance	2136118303	RCV002038445\|RCV002386931;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573726	64573726	64573726	-
NM_001370259.2(MEN1):c.1026G>A (p.Ala342=)	4221	MEN1	Likely benign	878855184	RCV000232744\|RCV000573264\|RCV003401187;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	11	64573727	64573727	NC_000011.9:g.64573727C>T	ClinGen:CA10582935	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1026G>C (p.Ala342=)	4221	MEN1	Likely benign	878855184	RCV001490737\|RCV003160982;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573727	64573727	64573727	-
NM_001370259.2(MEN1):c.1025C>T (p.Ala342Val)	4221	MEN1	Uncertain significance	377715802	RCV000531650\|RCV002384057;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573728	64573728	NC_000011.9:g.64573728G>A	ClinGen:CA059707	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1024del (p.Ala342fs)	4221	MEN1	Pathogenic	1555164986	RCV000509058;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573729	64573729	11:g.64573729_64573729del	OMIM:613733.0008,ClinGen:CA658653653	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1024G>C (p.Ala342Pro)	4221	MEN1	Likely pathogenic	776561706	RCV000632117;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573729	64573729	NC_000011.9:g.64573729C>G	ClinGen:CA381183224	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1018_1024del (p.Ala340fs)	4221	MEN1	Pathogenic	1941717148	RCV001203263;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573729	64573735	11:g.64573729_64573735del	-
NM_001370259.2(MEN1):c.1023G>C (p.Trp341Cys)	4221	MEN1	Uncertain significance	-1	RCV003121439;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573730	64573730	NC_000011.9:g.64573730C>G	-
NM_001370259.2(MEN1):c.1022G>A (p.Trp341Ter)	4221	MEN1	Pathogenic	1114167482	RCV000491036\|RCV000538522;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573731	64573731	NC_000011.9:g.64573731C>T	ClinGen:CA381183230	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1020C>A (p.Ala340=)	4221	MEN1	Likely benign	1060503796	RCV000474535\|RCV000564612;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573733	64573733	NC_000011.9:g.64573733G>T	ClinGen:CA16613683	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1019C>G (p.Ala340Gly)	4221	MEN1	Uncertain significance	2136118671	RCV002049280;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573734	64573734	64573734	-
NM_001370259.2(MEN1):c.1018G>C (p.Ala340Pro)	4221	MEN1	Uncertain significance	2136118718	RCV001969883;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573735	64573735	64573735	-
NM_001370259.2(MEN1):c.1017G>A (p.Gln339=)	4221	MEN1	Likely benign	-1	RCV002861761;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573736	64573736		-
NM_001370259.2(MEN1):c.1013dup (p.Gln339fs)	4221	MEN1	Likely pathogenic	386134245	RCV000030191;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573739	64573740	11:g.64573739_64573740insA	ClinGen:CA260439	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1013del (p.Leu338fs)	4221	MEN1	Pathogenic	2136118927	RCV001382910;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573740	64573740	64573739	-
NM_001370259.2(MEN1):c.1012C>G (p.Leu338Val)	4221	MEN1	Conflicting interpretations of pathogenicity	759337318	RCV000468728\|RCV001016949\|RCV003231485;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	11	64573741	64573741	NC_000011.9:g.64573741G>C	ClinGen:CA059690	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1011C>G (p.Ala337=)	4221	MEN1	Likely benign	-1	RCV002843913;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573742	64573742		-
NM_001370259.2(MEN1):c.1007_1009dup (p.Glu336dup)	4221	MEN1	Uncertain significance	1114167529	RCV000491786\|RCV001041721;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573743	64573744	NC_000011.9:g.64573745_64573747dup	ClinGen:CA645369577	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1010C>A (p.Ala337Asp)	4221	MEN1	Pathogenic	2136118998	RCV001382548\|RCV002319708;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573743	64573743	64573743	-
NM_001370259.2(MEN1):c.1009G>C (p.Ala337Pro)	4221	MEN1	Likely pathogenic	2071312	RCV000467805;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573744	64573744	NC_000011.9:g.64573744C>G	ClinGen:CA16613621	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1006dup (p.Glu336fs)	4221	MEN1	Pathogenic	2136119153	RCV001380466;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573746	64573747	64573746	-
NM_001370259.2(MEN1):c.1004G>A (p.Arg335Gln)	4221	MEN1	Uncertain significance	764998893	RCV000466812\|RCV002402228;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573749	64573749	NC_000011.9:g.64573749C>T	ClinGen:CA059675	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1003C>A (p.Arg335=)	4221	MEN1	Conflicting interpretations of pathogenicity	371364206	RCV000246806\|RCV000461335\|RCV000568413\|RCV001108573;	N	MedGen:CN169374\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|Human Phenotype Ontology:HP:0000843,MONDO:MONDO:0001741,MedGen:C0020502	11	64573750	64573750	NC_000011.9:g.64573750G>T	ClinGen:CA059657	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1003C>T (p.Arg335Trp)	4221	MEN1	Uncertain significance	371364206	RCV000525951\|RCV001009661;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573750	64573750	11:g.64573750G>A	ClinGen:CA381183266	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.1003C>G (p.Arg335Gly)	4221	MEN1	Uncertain significance	371364206	RCV002010611\|RCV002398081;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573750	64573750	64573750	-
NM_001370259.2(MEN1):c.999T>C (p.Asn333=)	4221	MEN1	Likely benign	763133775	RCV000469063\|RCV000563547\|RCV002282163;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN169374	11	64573754	64573754	NC_000011.9:g.64573754A>G	ClinGen:CA061927	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.996C>T (p.Arg332=)	4221	MEN1	Likely benign	2136119464	RCV001392528;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573757	64573757	64573757	-
NM_001370259.2(MEN1):c.995G>A (p.Arg332His)	4221	MEN1	Uncertain significance	2136119513	RCV001367135;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573758	64573758	64573758	-
NM_001370259.2(MEN1):c.995G>T (p.Arg332Leu)	4221	MEN1	Uncertain significance	-1	RCV002654367\|RCV003308218;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573758	64573758	NC_000011.9:g.64573758C>A	-
NM_001370259.2(MEN1):c.994C>T (p.Arg332Cys)	4221	MEN1	Uncertain significance	1941721650	RCV001235174;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573759	64573759	11:g.64573759G>A	-
NM_001370259.2(MEN1):c.993C>T (p.Asn331=)	4221	MEN1	Likely benign	370176253	RCV000457874\|RCV000490867;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573760	64573760	NC_000011.9:g.64573760G>A	ClinGen:CA061914	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.990C>A (p.Arg330=)	4221	MEN1	Likely benign	1359880787	RCV002136434\|RCV003382857;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573763	64573763	64573763	-
NM_001370259.2(MEN1):c.990C>T (p.Arg330=)	4221	MEN1	Likely benign	1359880787	RCV002139327;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573763	64573763	64573763	-
NM_001370259.2(MEN1):c.989G>T (p.Arg330Leu)	4221	MEN1	Uncertain significance	373135175	RCV000460980;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573764	64573764	NC_000011.9:g.64573764C>A	ClinGen:CA16613625	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.989G>C (p.Arg330Pro)	4221	MEN1	Uncertain significance	373135175	RCV000527000;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573764	64573764	NC_000011.9:g.64573764C>G	ClinGen:CA381183296	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.989G>A (p.Arg330His)	4221	MEN1	Uncertain significance	373135175	RCV000573622\|RCV000632116\|RCV003332206;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900	11	64573764	64573764	11:g.64573764C>T	ClinGen:CA061906	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.988C>T (p.Arg330Cys)	4221	MEN1	Uncertain significance	1565644005	RCV000691929\|RCV001019861;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573765	64573765	11:g.64573765G>A	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.988C>G (p.Arg330Gly)	4221	MEN1	Uncertain significance	1565644005	RCV001216471;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573765	64573765	11:g.64573765G>C	-
NM_001370259.2(MEN1):c.984C>T (p.His328=)	4221	MEN1	Likely benign	757323408	RCV000938389;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573769	64573769	11:g.64573769G>A	-
NM_001370259.2(MEN1):c.970_984del (p.Leu324_His328del)	4221	MEN1	Likely pathogenic	1941723156	RCV001307430;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573769	64573783	64573768	-
NM_001370259.2(MEN1):c.982C>G (p.His328Asp)	4221	MEN1	Uncertain significance	794727882	RCV000179998\|RCV000632139;	N	MedGen:CN517202\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573771	64573771	11:g.64573771G>C	ClinGen:CA009664	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.982C>A (p.His328Asn)	4221	MEN1	Uncertain significance	794727882	RCV000690773;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573771	64573771	NC_000011.9:g.64573771G>T	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.982C>T (p.His328Tyr)	4221	MEN1	Uncertain significance	794727882	RCV002034260;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573771	64573771	64573771	-
NM_001370259.2(MEN1):c.981C>T (p.Tyr327=)	4221	MEN1	Likely benign	1592643488	RCV000865369\|RCV002372421;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573772	64573772	11:g.64573772G>A	-
NM_001370259.2(MEN1):c.981C>G (p.Tyr327Ter)	4221	MEN1	Pathogenic	1592643488	RCV001960715;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573772	64573772	64573772	-
NM_001370259.2(MEN1):c.980A>G (p.Tyr327Cys)	4221	MEN1	Uncertain significance	377403837	RCV000695160\|RCV003117492;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900	11	64573773	64573773	NC_000011.9:g.64573773T>C	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.978C>T (p.Gly326=)	4221	MEN1	Likely benign	1555165071	RCV000550736\|RCV002384059;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573775	64573775	NC_000011.9:g.64573775G>A	ClinGen:CA474983321	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.974C>A (p.Ala325Asp)	4221	MEN1	Uncertain significance	370840265	RCV000533724;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573779	64573779	11:g.64573779G>T	ClinGen:CA381183329	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.972G>A (p.Leu324=)	4221	MEN1	Uncertain significance	1592643568	RCV000809013;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573781	64573781	11:g.64573781C>T	-
NM_001370259.2(MEN1):c.972G>C (p.Leu324=)	4221	MEN1	Likely benign	1592643568	RCV001446383;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573781	64573781	64573781	-
NM_001370259.2(MEN1):c.970del (p.Leu324fs)	4221	MEN1	Pathogenic/Likely pathogenic	1114167508	RCV000491495\|RCV003464041;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573783	64573783	11:g.64573783_64573783del	ClinGen:CA645369580	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.969C>A (p.Tyr323Ter)	4221	MEN1	Pathogenic	750904332	RCV000469199\|RCV000492010\|RCV001269821;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	11	64573784	64573784	NC_000011.9:g.64573784G>T	ClinGen:CA16613392	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.969C>G (p.Tyr323Ter)	4221	MEN1	Pathogenic	750904332	RCV000521767\|RCV000632110;	N	MedGen:CN517202\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573784	64573784	11:g.64573784G>C	ClinGen:CA381183338	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.969C>T (p.Tyr323=)	4221	MEN1	Likely benign	-1	RCV002387007\|RCV003094857;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573784	64573784		-
NM_001370259.2(MEN1):c.966G>A (p.Met322Ile)	4221	MEN1	Uncertain significance	947594206	RCV000707510;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573787	64573787	11:g.64573787C>T	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.965T>C (p.Met322Thr)	4221	MEN1	Uncertain significance	1941725569	RCV001108575\|RCV001108574;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|Human Phenotype Ontology:HP:0000843,MONDO:MONDO:0001741,MedGen:C0020502	11	64573788	64573788	11:g.64573788A>G	-
NM_001370259.2(MEN1):c.965T>G (p.Met322Arg)	4221	MEN1	Uncertain significance	1941725569	RCV001296671;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573788	64573788	64573788	-
NM_001370259.2(MEN1):c.965T>A (p.Met322Lys)	4221	MEN1	Uncertain significance	-1	RCV002725447;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573788	64573788	NC_000011.9:g.64573788A>T	-
NM_001370259.2(MEN1):c.964A>T (p.Met322Leu)	4221	MEN1	Uncertain significance	1555165089	RCV000557965\|RCV002377019;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573789	64573789	11:g.64573789T>A	ClinGen:CA381183350	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.964A>G (p.Met322Val)	4221	MEN1	Uncertain significance	1555165089	RCV000632095;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573789	64573789	NC_000011.9:g.64573789T>C	ClinGen:CA381183351	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.963C>T (p.Tyr321=)	4221	MEN1	Likely benign	1555165094	RCV000632177\|RCV001019580;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573790	64573790	NC_000011.9:g.64573790G>A	ClinGen:CA474983347	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.963C>A (p.Tyr321Ter)	4221	MEN1	Pathogenic	1555165094	RCV001996735;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573790	64573790	64573790	-
NM_001370259.2(MEN1):c.960C>G (p.Pro320=)	4221	MEN1	Likely benign	1592643701	RCV001410508;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573793	64573793	11:g.64573793G>C	-
NM_001370259.2(MEN1):c.958C>T (p.Pro320Ser)	4221	MEN1	Uncertain significance	1941726727	RCV001345277\|RCV002384474;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573795	64573795	64573795	-
NM_001370259.2(MEN1):c.958C>G (p.Pro320Ala)	4221	MEN1	Uncertain significance	1941726727	RCV001952260;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573795	64573795	64573795	-
NM_001370259.2(MEN1):c.955dup (p.Tyr319fs)	4221	MEN1	Likely pathogenic	386134261	RCV000030211;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573797	64573798	11:g.64573797_64573798insA	ClinGen:CA260475	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.955T>G (p.Tyr319Asp)	4221	MEN1	Uncertain significance	1555165101	RCV000545546;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573798	64573798	11:g.64573798A>C	ClinGen:CA381183374	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.954C>A (p.Ile318=)	4221	MEN1	Likely benign	2136120737	RCV001403075;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573799	64573799	64573799	-
NM_001370259.2(MEN1):c.954C>T (p.Ile318=)	4221	MEN1	Likely benign	2136120737	RCV002090682\|RCV002372891;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573799	64573799	64573799	-
NM_001370259.2(MEN1):c.952A>G (p.Ile318Val)	4221	MEN1	Uncertain significance	1565644220	RCV000703285;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573801	64573801	NC_000011.9:g.64573801T>C	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.949C>T (p.His317Tyr)	4221	MEN1	Likely pathogenic	2136120898	RCV002031634\|RCV002372824\|RCV002479828;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	11	64573804	64573804	64573804	-
NM_001370259.2(MEN1):c.948A>T (p.Glu316Asp)	4221	MEN1	Uncertain significance	756604268	RCV001040248\|RCV002445226;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573805	64573805	11:g.64573805T>A	-
NM_001370259.2(MEN1):c.946G>A (p.Glu316Lys)	4221	MEN1	Uncertain significance	780563052	RCV001294321;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573807	64573807	64573807	-
NM_001370259.2(MEN1):c.943G>T (p.Asp315Tyr)	4221	MEN1	Conflicting interpretations of pathogenicity	747851909	RCV000494086\|RCV001202722;	N	MedGen:CN517202\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573810	64573810	11:g.64573810C>A	ClinGen:CA061863	CN517202 not provided;
NM_001370259.2(MEN1):c.943G>C (p.Asp315His)	4221	MEN1	Uncertain significance	747851909	RCV001980488;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573810	64573810	64573810	-
NM_001370259.2(MEN1):c.943del (p.Asp315fs)	4221	MEN1	Pathogenic	-1	RCV002475092\|RCV002569404;	N	MedGen:CN517202\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573810	64573810	NC_000011.9:g.64573812del	-
NM_001370259.2(MEN1):c.942G>A (p.Arg314=)	4221	MEN1	Likely benign	-1	RCV003115577;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573811	64573811		-
NM_001370259.2(MEN1):c.941G>A (p.Arg314Gln)	4221	MEN1	Conflicting interpretations of pathogenicity	771645621	RCV000573174\|RCV000632120\|RCV001103402\|RCV002307550;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|Human Phenotype Ontology:HP:0000843,MONDO:MONDO:0001741,MedGen:C0020502\|MedGen:C3661900	11	64573812	64573812	11:g.64573812C>T	ClinGen:CA061855	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.941G>T (p.Arg314Leu)	4221	MEN1	Uncertain significance	-1	RCV002834451;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573812	64573812	NC_000011.9:g.64573812C>A	-
NM_001370259.2(MEN1):c.940C>T (p.Arg314Trp)	4221	MEN1	Uncertain significance	139936447	RCV001053228;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573813	64573813	11:g.64573813G>A	-
NM_001370259.2(MEN1):c.940C>G (p.Arg314Gly)	4221	MEN1	Uncertain significance	139936447	RCV001961141;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573813	64573813	64573813	-
NM_001370259.2(MEN1):c.936C>G (p.Tyr312Ter)	4221	MEN1	Pathogenic	386134260	RCV000030210\|RCV000082340\|RCV002371793;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573817	64573817	11:g.64573817G>C	ClinGen:CA009655	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.936C>A (p.Tyr312Ter)	4221	MEN1	Pathogenic	386134260	RCV001382417;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573817	64573817	64573817	-
NM_001370259.2(MEN1):c.936C>T (p.Tyr312=)	4221	MEN1	Likely benign	386134260	RCV001498978\|RCV002377870;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573817	64573817	64573817	-
NM_001370259.2(MEN1):c.935A>T (p.Tyr312Phe)	4221	MEN1	Uncertain significance	1592643944	RCV000813834;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573818	64573818	11:g.64573818T>A	-
NM_001370259.2(MEN1):c.933C>A (p.Thr311=)	4221	MEN1	Likely benign	1592643965	RCV001498250;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573820	64573820	64573820	-
NM_001370259.2(MEN1):c.933C>T (p.Thr311=)	4221	MEN1	Likely benign	-1	RCV002371662\|RCV003100148;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573820	64573820		-
NM_001370259.2(MEN1):c.932C>T (p.Thr311Ile)	4221	MEN1	Uncertain significance	1565644342	RCV000692458;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573821	64573821	NC_000011.9:g.64573821G>A	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.930G>T (p.Lys310Asn)	4221	MEN1	Uncertain significance	1941731256	RCV001247545;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573823	64573823	11:g.64573823C>A	-
NM_001370259.2(MEN1):c.927C>G (p.Ala309=)	4221	MEN1	Likely benign	-1	RCV002863235;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573826	64573826		-
NM_001370259.2(MEN1):c.921C>T (p.Ala307=)	4221	MEN1	Likely benign	1060503788	RCV000474055;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573832	64573832	NC_000011.9:g.64573832G>A	ClinGen:CA16613399	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.921C>G (p.Ala307=)	4221	MEN1	Likely benign	1060503788	RCV002123150;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573832	64573832	64573832	-
NM_001370259.2(MEN1):c.916A>G (p.Ile306Val)	4221	MEN1	Uncertain significance	-1	RCV002966534;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573837	64573837	NC_000011.9:g.64573837T>C	-
NM_130799.2(MEN1):c.914del	4221	MEN1	Pathogenic	1941733228	RCV001047385;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573839	64573839	11:g.64573839_64573839del	-
NM_001370259.2(MEN1):c.914G>A (p.Gly305Asp)	4221	MEN1	Uncertain significance	1592644100	RCV002007070;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573839	64573839	64573839	-
NM_001370259.2(MEN1):c.913G>A (p.Gly305Ser)	4221	MEN1	Uncertain significance	1555165146	RCV000545782\|RCV002377018;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64573840	64573840	NC_000011.9:g.64573840C>T	ClinGen:CA381183461	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.913-1G>A	4221	MEN1	Pathogenic/Likely pathogenic	1057518572	RCV000414731\|RCV001018907\|RCV001851002;	N	MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573841	64573841	11:g.64573841C>T	ClinGen:CA16042860	CN517202 not provided;
NM_001370259.2(MEN1):c.913-1G>C	4221	MEN1	Pathogenic	1057518572	RCV002000024;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573841	64573841	64573841	-
NM_001370259.2(MEN1):c.913-2A>G	4221	MEN1	Pathogenic/Likely pathogenic	1114167498	RCV000492022\|RCV000632096;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573842	64573842	11:g.64573842T>C	ClinGen:CA381183467	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.913-4C>T	4221	MEN1	Likely benign	770413697	RCV000508136\|RCV000533306;	N	MedGen:CN169374\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573844	64573844	NC_000011.9:g.64573844G>A	ClinGen:CA061834	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.913-7C>T	4221	MEN1	Likely benign	911501970	RCV001464676;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573847	64573847	64573847	-
NM_001370259.2(MEN1):c.913-8C>T	4221	MEN1	Likely benign	373893527	RCV001448716;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573848	64573848	11:g.64573848G>A	-
NM_001370259.2(MEN1):c.913-10C>T	4221	MEN1	Likely benign	2136122123	RCV001419069;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573850	64573850	64573850	-
NM_001370259.2(MEN1):c.913-11C>T	4221	MEN1	Likely benign	2136122142	RCV002150296;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573851	64573851	64573851	-
NM_001370259.2(MEN1):c.913-12A>C	4221	MEN1	Likely benign	-1	RCV003025315;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573852	64573852	NC_000011.9:g.64573852T>G	-
NM_001370259.2(MEN1):c.913-13C>T	4221	MEN1	Likely benign	1309344851	RCV002151750;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573853	64573853	64573853	-
NM_001370259.2(MEN1):c.913-15del	4221	MEN1	Likely benign	2136122252	RCV002132976;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573855	64573855	64573854	-
NM_001370259.2(MEN1):c.913-15C>T	4221	MEN1	Likely benign	1941734915	RCV002128776;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64573855	64573855	64573855	-
NM_001370259.2(MEN1):c.913-42G>C	4221	MEN1	Benign	529037188	RCV000663275\|RCV002258999\|RCV003230273\|RCV003311876;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0009050,MedGen:C0221406,OMIM:219090, Orphanet:96253\|MedGen:C3661900	11	64573882	64573882	11:g.64573882C>G	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.912+20G>T	4221	MEN1	Likely benign	-1	RCV002620886;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574463	64574463	NC_000011.9:g.64574463C>A	-
NM_001370259.2(MEN1):c.912+19G>A	4221	MEN1	Likely benign	780657282	RCV002175953;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574464	64574464	64574464	-
NM_001370259.2(MEN1):c.912+13A>G	4221	MEN1	Likely benign	754283643	RCV002151029;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574470	64574470	64574470	-
NM_001370259.2(MEN1):c.912+10T>C	4221	MEN1	Likely benign	1565645317	RCV000919028;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574473	64574473	11:g.64574473A>G	-
NM_001370259.2(MEN1):c.912+6G>T	4221	MEN1	Uncertain significance	755302991	RCV001209296;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574477	64574477	11:g.64574477C>A	-
NM_001370259.2(MEN1):c.912+5G>A	4221	MEN1	Uncertain significance	1592646185	RCV000794481;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574478	64574478	11:g.64574478C>T	-
NM_001370259.2(MEN1):c.912+5G>C	4221	MEN1	Uncertain significance	1592646185	RCV001312423;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574478	64574478	64574478	-
NM_001370259.2(MEN1):c.912+3G>T	4221	MEN1	Uncertain significance	-1	RCV002863724;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574480	64574480	NC_000011.9:g.64574480C>A	-
NM_001370259.2(MEN1):c.912+2T>G	4221	MEN1	Pathogenic	1555165256	RCV001926059;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574481	64574481	64574481	-
NM_001370259.2(MEN1):c.912+1G>A	4221	MEN1	Pathogenic	398124437	RCV000082339\|RCV000491428\|RCV001382549;	N	MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574482	64574482	11:g.64574482C>T	ClinGen:CA009649	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.912+1G>C	4221	MEN1	Pathogenic	398124437	RCV000490972\|RCV000552470;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574482	64574482	11:g.64574482C>G	ClinGen:CA381183474	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.912G>A (p.Lys304=)	4221	MEN1	Conflicting interpretations of pathogenicity	1592646211	RCV001018904\|RCV001000963;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574483	64574483	11:g.64574483C>T	-
NM_001370259.2(MEN1):c.912G>T (p.Lys304Asn)	4221	MEN1	Likely pathogenic	1592646211	RCV001175140;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574483	64574483	11:g.64574483C>A	-
NM_001370259.2(MEN1):c.910A>G (p.Lys304Glu)	4221	MEN1	Uncertain significance	1941774610	RCV001208050\|RCV003163576\|RCV003332303;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	11	64574485	64574485	11:g.64574485T>C	-
NM_001370259.2(MEN1):c.909C>T (p.His303=)	4221	MEN1	Likely benign	878855200	RCV000230220\|RCV002444926;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64574486	64574486	NC_000011.9:g.64574486G>A	ClinGen:CA10582936	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.908A>G (p.His303Arg)	4221	MEN1	Conflicting interpretations of pathogenicity	373805140	RCV000819277\|RCV002372330;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64574487	64574487	11:g.64574487T>C	-
NM_001370259.2(MEN1):c.907C>T (p.His303Tyr)	4221	MEN1	Uncertain significance	1941775165	RCV001299046\|RCV002447280;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64574488	64574488	64574488	-
NM_001370259.2(MEN1):c.906C>T (p.Tyr302=)	4221	MEN1	Likely benign	1592646265	RCV001398447;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574489	64574489	11:g.64574489G>A	-
NM_001370259.2(MEN1):c.903C>T (p.Leu301=)	4221	MEN1	Likely benign	1592646283	RCV001466277\|RCV002372597;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64574492	64574492	11:g.64574492G>A	-
NM_001370259.2(MEN1):c.903C>G (p.Leu301=)	4221	MEN1	Likely benign	1592646283	RCV001484984\|RCV003382609;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64574492	64574492	64574492	-
NM_001370259.2(MEN1):c.902T>C (p.Leu301Pro)	4221	MEN1	Uncertain significance	2136127925	RCV001360730;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574493	64574493	64574493	-
NM_001370259.2(MEN1):c.901C>A (p.Leu301Ile)	4221	MEN1	Uncertain significance	1941775680	RCV001056839;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574494	64574494	11:g.64574494G>T	-
NM_001370259.2(MEN1):c.900C>T (p.Thr300=)	4221	MEN1	Likely benign	1592646297	RCV001489746\|RCV002372618;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64574495	64574495	11:g.64574495G>A	-
NM_001370259.2(MEN1):c.899C>T (p.Thr300Ile)	4221	MEN1	Uncertain significance	1941776482	RCV001211267\|RCV002375161\|RCV003314679;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C5669877	11	64574496	64574496	11:g.64574496G>A	-
NM_001370259.2(MEN1):c.898A>T (p.Thr300Ser)	4221	MEN1	Uncertain significance	1592646309	RCV001018589\|RCV001363994;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574497	64574497	11:g.64574497T>A	-
NM_001370259.2(MEN1):c.897C>T (p.Leu299=)	4221	MEN1	Conflicting interpretations of pathogenicity	1409781409	RCV000940816\|RCV001818913;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:CN169374	11	64574498	64574498	11:g.64574498G>A	-
NM_001370259.2(MEN1):c.895C>G (p.Leu299Val)	4221	MEN1	Uncertain significance	1592646339	RCV001018545\|RCV002549479;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574500	64574500	11:g.64574500G>C	-
NM_001370259.2(MEN1):c.895C>A (p.Leu299Ile)	4221	MEN1	Uncertain significance	1592646339	RCV001231823\|RCV002375235;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64574500	64574500	11:g.64574500G>T	-
NM_001370259.2(MEN1):c.894A>C (p.Pro298=)	4221	MEN1	Likely benign	-1	RCV003034098;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574501	64574501		-
NM_001370259.2(MEN1):c.893C>T (p.Pro298Leu)	4221	MEN1	Uncertain significance	2136128195	RCV002025174\|RCV002442991;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64574502	64574502	64574502	-
NM_001370259.2(MEN1):c.892C>G (p.Pro298Ala)	4221	MEN1	Uncertain significance	1555165268	RCV000632085\|RCV002377359;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64574503	64574503	NC_000011.9:g.64574503G>C	ClinGen:CA381183520	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.890A>G (p.Asp297Gly)	4221	MEN1	Uncertain significance	1592646361	RCV001018488\|RCV001212724;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574505	64574505	11:g.64574505T>C	-
NM_001370259.2(MEN1):c.886C>T (p.Pro296Ser)	4221	MEN1	Uncertain significance	1941777494	RCV001307785;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574509	64574509	64574509	-
NM_001370259.2(MEN1):c.885G>A (p.Arg295=)	4221	MEN1	Likely benign	-1	RCV002886590;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574510	64574510		-
NM_001370259.2(MEN1):c.884G>A (p.Arg295Gln)	4221	MEN1	Conflicting interpretations of pathogenicity	1397110438	RCV000544579\|RCV003343896;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64574511	64574511	NC_000011.9:g.64574511C>T	ClinGen:CA381183538	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.883C>T (p.Arg295Trp)	4221	MEN1	Uncertain significance	1046929915	RCV000470592\|RCV000491071\|RCV003392263;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|	11	64574512	64574512	NC_000011.9:g.64574512G>A	ClinGen:CA16613627	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.881G>A (p.Gly294Asp)	4221	MEN1	Uncertain significance	1941778425	RCV001038270;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574514	64574514	11:g.64574514C>T	-
NM_001370259.2(MEN1):c.880G>A (p.Gly294Ser)	4221	MEN1	Uncertain significance	1565645429	RCV000686248;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574515	64574515	NC_000011.9:g.64574515C>T	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.879del (p.Gly294fs)	4221	MEN1	Pathogenic	-1	RCV003037406;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574516	64574516	NC_000011.9:g.64574516del	-
NM_001370259.2(MEN1):c.877C>G (p.Pro293Ala)	4221	MEN1	Uncertain significance	2136128745	RCV001884055;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574518	64574518	64574518	-
NM_001370259.2(MEN1):c.877C>T (p.Pro293Ser)	4221	MEN1	Uncertain significance	-1	RCV002843469;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574518	64574518	NC_000011.9:g.64574518G>A	-
NM_001370259.2(MEN1):c.876C>T (p.Thr292=)	4221	MEN1	Likely benign	756782257	RCV001413493\|RCV002377644;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64574519	64574519	64574519	-
NM_001370259.2(MEN1):c.876C>G (p.Thr292=)	4221	MEN1	Likely benign	756782257	RCV002193835\|RCV002373033;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64574519	64574519	64574519	-
NM_001370259.2(MEN1):c.875C>T (p.Thr292Ile)	4221	MEN1	Uncertain significance	780646691	RCV001058116\|RCV002374938;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64574520	64574520	11:g.64574520G>A	-
NM_001370259.2(MEN1):c.872C>G (p.Pro291Arg)	4221	MEN1	Uncertain significance	745857419	RCV001885742\|RCV002370422;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64574523	64574523	64574523	-
NM_001370259.2(MEN1):c.871C>G (p.Pro291Ala)	4221	MEN1	Uncertain significance	1413160325	RCV001978411;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574524	64574524	64574524	-
NM_001370259.2(MEN1):c.871C>T (p.Pro291Ser)	4221	MEN1	Uncertain significance	-1	RCV003105139;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574524	64574524	NC_000011.9:g.64574524G>A	-
NM_001370259.2(MEN1):c.869A>C (p.Glu290Ala)	4221	MEN1	Uncertain significance	1213891703	RCV000532389\|RCV001821504\|RCV002377017;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:CN169374\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64574526	64574526	NC_000011.9:g.64574526T>G	ClinGen:CA381183566	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.869A>T (p.Glu290Val)	4221	MEN1	Uncertain significance	1213891703	RCV000797291\|RCV002370093;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64574526	64574526	11:g.64574526T>A	-
NM_001370259.2(MEN1):c.869A>G (p.Glu290Gly)	4221	MEN1	Uncertain significance	-1	RCV003064156;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574526	64574526	NC_000011.9:g.64574526T>C	-
NM_001370259.2(MEN1):c.868G>A (p.Glu290Lys)	4221	MEN1	Uncertain significance	1335117435	RCV000800612\|RCV001018178;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64574527	64574527	11:g.64574527C>T	-
NM_001370259.2(MEN1):c.868G>C (p.Glu290Gln)	4221	MEN1	Uncertain significance	1335117435	RCV001303715;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574527	64574527	64574527	-
NM_001370259.2(MEN1):c.864G>A (p.Glu288=)	4221	MEN1	Likely benign	769748450	RCV002082950\|RCV002372878;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64574531	64574531	64574531	-
NM_001370259.2(MEN1):c.862G>T (p.Glu288Ter)	4221	MEN1	Pathogenic	-1	RCV003032284;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574533	64574533	NC_000011.9:g.64574533C>A	-
NM_001370259.2(MEN1):c.861G>A (p.Glu287=)	4221	MEN1	Likely benign	1336658836	RCV000924640\|RCV002445030;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64574534	64574534	11:g.64574534C>T	-
NM_001370259.2(MEN1):c.859G>T (p.Glu287Ter)	4221	MEN1	Pathogenic	2136129231	RCV001872787;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574536	64574536	64574536	-
NM_001370259.2(MEN1):c.856C>T (p.Leu286=)	4221	MEN1	Likely benign	542321016	RCV000556338\|RCV000574622;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64574539	64574539	11:g.64574539G>A	ClinGen:CA061722	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.854A>C (p.Asp285Ala)	4221	MEN1	Uncertain significance	2136129327	RCV001969519;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574541	64574541	64574541	-
NM_001370259.2(MEN1):c.852A>G (p.Ala284=)	4221	MEN1	Likely benign	2136129359	RCV002076478\|RCV002443206;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64574543	64574543	64574543	-
NM_001370259.2(MEN1):c.851C>A (p.Ala284Glu)	4221	MEN1	Likely pathogenic	1565645563	RCV000695678;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574544	64574544	NC_000011.9:g.64574544G>T	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.849G>A (p.Leu283=)	4221	MEN1	Likely benign	1592646641	RCV001017915\|RCV001413430;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574546	64574546	11:g.64574546C>T	-
NM_001370259.2(MEN1):c.849G>T (p.Leu283=)	4221	MEN1	Uncertain significance	1592646641	RCV001103404\|RCV001103403;	N	Human Phenotype Ontology:HP:0000843,MONDO:MONDO:0001741,MedGen:C0020502\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574546	64574546	11:g.64574546C>A	-
NM_001370259.2(MEN1):c.846C>T (p.Asn282=)	4221	MEN1	Likely benign	2136129516	RCV002163359;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574549	64574549	64574549	-
NM_001370259.2(MEN1):c.845A>G (p.Asn282Ser)	4221	MEN1	Uncertain significance	1592646672	RCV001017836\|RCV002550833;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574550	64574550	11:g.64574550T>C	-
NM_001370259.2(MEN1):c.843G>C (p.Gly281=)	4221	MEN1	Benign/Likely benign	562620826	RCV000461482\|RCV000569444;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64574552	64574552	NC_000011.9:g.64574552C>G	ClinGen:CA061712	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.839T>C (p.Leu280Ser)	4221	MEN1	Conflicting interpretations of pathogenicity	368619946	RCV000797745\|RCV001017703\|RCV003424344;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|	11	64574556	64574556	11:g.64574556A>G	-
NM_001370259.2(MEN1):c.839T>A (p.Leu280Ter)	4221	MEN1	Pathogenic	-1	RCV003047625;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574556	64574556	NC_000011.9:g.64574556A>T	-
NM_001370259.2(MEN1):c.837C>T (p.Ala279=)	4221	MEN1	Likely benign	762092675	RCV000226318\|RCV001017650;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64574558	64574558	NC_000011.9:g.64574558G>A	ClinGen:CA061700	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.837del (p.Ala279_Leu280insTer)	4221	MEN1	Pathogenic	-1	RCV003029869;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574558	64574558	NC_000011.9:g.64574559del	-
NM_001370259.2(MEN1):c.833T>G (p.Met278Arg)	4221	MEN1	Uncertain significance	1592646765	RCV000810806;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574562	64574562	11:g.64574562A>C	-
NM_001370259.2(MEN1):c.832A>G (p.Met278Val)	4221	MEN1	Uncertain significance	1475401656	RCV001968522;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574563	64574563	64574563	-
NM_001370259.2(MEN1):c.831del (p.Met278fs)	4221	MEN1	Pathogenic	2136129908	RCV001385369;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574564	64574564	64574563	-
NM_001370259.2(MEN1):c.830C>A (p.Pro277His)	4221	MEN1	Conflicting interpretations of pathogenicity	1060499973	RCV000471154\|RCV000568673\|RCV001824785;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN169374	11	64574565	64574565	NC_000011.9:g.64574565G>T	ClinGen:CA16613405	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.830C>T (p.Pro277Leu)	4221	MEN1	Uncertain significance	1060499973	RCV000539049\|RCV001811031;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900	11	64574565	64574565	11:g.64574565G>A	ClinGen:CA381183763	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.829_830insTAGAGGTTC (p.Tyr276_Pro277insLeuGluVal)	4221	MEN1	Uncertain significance	2136130018	RCV002022980;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574565	64574566	64574565	-
NM_001370259.2(MEN1):c.828C>T (p.Tyr276=)	4221	MEN1	Likely benign	1060503789	RCV000456598\|RCV000562412;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64574567	64574567	NC_000011.9:g.64574567G>A	ClinGen:CA16613406	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.828C>A (p.Tyr276Ter)	4221	MEN1	Pathogenic	1060503789	RCV000484977\|RCV000491793\|RCV000823755;	N	MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574567	64574567	NC_000011.9:g.64574567G>T	ClinGen:CA16619360	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.827A>G (p.Tyr276Cys)	4221	MEN1	Uncertain significance	1555165327	RCV000565609\|RCV000632097;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574568	64574568	11:g.64574568T>C	ClinGen:CA381183783	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.825-1_825del	4221	MEN1	Likely pathogenic	2136130282	RCV002043184;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574570	64574571	64574569	-
NM_001370259.2(MEN1):c.825G>A (p.Arg275=)	4221	MEN1	Uncertain significance	-1	RCV003047246;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574570	64574570		-
NM_001370259.2(MEN1):c.825-4C>A	4221	MEN1	Likely benign	2136130374	RCV002157069;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574574	64574574	64574574	-
NM_001370259.2(MEN1):c.825-8T>C	4221	MEN1	Likely benign	1555165330	RCV000526614;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574578	64574578	NC_000011.9:g.64574578A>G	ClinGen:CA658656167	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.825-9C>A	4221	MEN1	Likely benign	1460138191	RCV002213968;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574579	64574579	64574579	-
NM_001370259.2(MEN1):c.825-10C>G	4221	MEN1	Likely benign	999121619	RCV000419286\|RCV000460067;	N	MedGen:CN169374\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574580	64574580	11:g.64574580G>C	ClinGen:CA16606354	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.825-10C>T	4221	MEN1	Likely benign	-1	RCV003054552;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574580	64574580	NC_000011.9:g.64574580G>A	-
NM_001370259.2(MEN1):c.825-11T>C	4221	MEN1	Likely benign	375364751	RCV002112704;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574581	64574581	64574581	-
NM_001370259.2(MEN1):c.825-14T>C	4221	MEN1	Likely benign	773447061	RCV002130110;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574584	64574584	64574584	-
NM_001370259.2(MEN1):c.824+19C>G	4221	MEN1	Likely benign	1941789202	RCV002156656;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574632	64574632	64574632	-
NM_001370259.2(MEN1):c.824+18G>A	4221	MEN1	Likely benign	-1	RCV003093471;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574633	64574633	NC_000011.9:g.64574633C>T	-
NM_001370259.2(MEN1):c.824+17G>C	4221	MEN1	Likely benign	1271023864	RCV002206638;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574634	64574634	64574634	-
NM_001370259.2(MEN1):c.824+16T>A	4221	MEN1	Likely benign	-1	RCV002616961;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574635	64574635	NC_000011.9:g.64574635A>T	-
NM_001370259.2(MEN1):c.824+12del	4221	MEN1	Likely benign	2136132270	RCV002149395;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574639	64574639	64574638	-
NM_001370259.2(MEN1):c.824+12G>A	4221	MEN1	Likely benign	768402169	RCV002137063;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574639	64574639	64574639	-
NM_001370259.2(MEN1):c.824+9A>G	4221	MEN1	Likely benign	774166628	RCV002065477;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574642	64574642	11:g.64574642T>C	-
NM_001370259.2(MEN1):c.824+8G>T	4221	MEN1	Likely benign	2136132354	RCV002161957;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574643	64574643	64574643	-
NM_001370259.2(MEN1):c.824+3C>G	4221	MEN1	Uncertain significance	1941790535	RCV001066013;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574648	64574648	11:g.64574648G>C	-
NM_001370259.2(MEN1):c.824+1G>A	4221	MEN1	Pathogenic	1060499976	RCV000018190\|RCV002426511;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64574650	64574650	NC_000011.9:g.64574650C>T	OMIM:613733.0034	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.824+1G>T	4221	MEN1	Pathogenic	1060499976	RCV000466988;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574650	64574650	NC_000011.9:g.64574650C>A	ClinGen:CA16613409	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.824G>A (p.Arg275Lys)	4221	MEN1	Pathogenic	1187634059	RCV000820746\|RCV002427053;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64574651	64574651	11:g.64574651C>T	-
NM_001370259.2(MEN1):c.823del (p.Arg275fs)	4221	MEN1	Pathogenic	1555165360	RCV000632135\|RCV001269679;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:CN517202	11	64574652	64574652	NC_000011.9:g.64574654del	ClinGen:CA658797670	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.823A>G (p.Arg275Gly)	4221	MEN1	Uncertain significance	1592647235	RCV000793594\|RCV002406733;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64574652	64574652	11:g.64574652T>C	-
NM_001370259.2(MEN1):c.820G>A (p.Glu274Lys)	4221	MEN1	Uncertain significance	1941791593	RCV001215368;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574655	64574655	11:g.64574655C>T	-
NM_001370259.2(MEN1):c.819G>T (p.Leu273=)	4221	MEN1	Likely benign	748369241	RCV000232403\|RCV001027267;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64574656	64574656	NC_000011.9:g.64574656C>A	ClinGen:CA061617	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.818T>C (p.Leu273Pro)	4221	MEN1	Likely pathogenic	1592647281	RCV000804447\|RCV001269820;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900	11	64574657	64574657	11:g.64574657A>G	-
NM_001370259.2(MEN1):c.818T>G (p.Leu273Arg)	4221	MEN1	Likely pathogenic	-1	RCV002820945;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574657	64574657	NC_000011.9:g.64574657A>C	-
NM_001370259.2(MEN1):c.815A>G (p.His272Arg)	4221	MEN1	Uncertain significance	-1	RCV002846460;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574660	64574660	NC_000011.9:g.64574660T>C	-
NM_001370259.2(MEN1):c.812G>C (p.Gly271Ala)	4221	MEN1	Uncertain significance	1941792670	RCV001207821;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574663	64574663	11:g.64574663C>G	-
NM_001370259.2(MEN1):c.811G>A (p.Gly271Arg)	4221	MEN1	Uncertain significance	1565645918	RCV000705180;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574664	64574664	NC_000011.9:g.64574664C>T	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.811G>C (p.Gly271Arg)	4221	MEN1	Uncertain significance	-1	RCV002305361;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574664	64574664	64574664	-
NM_001370259.2(MEN1):c.809T>C (p.Leu270Pro)	4221	MEN1	Uncertain significance	1592647333	RCV001027173\|RCV001232103\|RCV003106101;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900	11	64574666	64574666	11:g.64574666A>G	-
NM_001370259.2(MEN1):c.808C>T (p.Leu270=)	4221	MEN1	Likely benign	371556177	RCV000928175\|RCV002416158;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64574667	64574667	11:g.64574667G>A	-
NM_001370259.2(MEN1):c.808C>A (p.Leu270Met)	4221	MEN1	Uncertain significance	371556177	RCV002045881;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574667	64574667	64574667	-
NM_001370259.2(MEN1):c.807C>T (p.Asp269=)	4221	MEN1	Likely benign	2136133470	RCV001482190;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574668	64574668	64574668	-
NM_001370259.2(MEN1):c.806A>G (p.Asp269Gly)	4221	MEN1	Uncertain significance	1941793463	RCV001071802;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574669	64574669	11:g.64574669T>C	-
NM_001370259.2(MEN1):c.805G>A (p.Asp269Asn)	4221	MEN1	Uncertain significance	878855199	RCV000228494;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574670	64574670	NC_000011.9:g.64574670C>T	ClinGen:CA10582937	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.803A>G (p.Tyr268Cys)	4221	MEN1	Conflicting interpretations of pathogenicity	773500082	RCV000199390\|RCV001027095\|RCV003148675;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	11	64574672	64574672	NC_000011.9:g.64574672T>C	ClinGen:CA061607	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.801C>G (p.Leu267=)	4221	MEN1	Likely benign	760850856	RCV000697467\|RCV002422540;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64574674	64574674	NC_000011.9:g.64574674G>C	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.795G>A (p.Trp265Ter)	4221	MEN1	Pathogenic	1592647398	RCV000808722\|RCV001269681;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:CN517202	11	64574680	64574680	11:g.64574680C>T	-
NM_001370259.2(MEN1):c.794G>A (p.Trp265Ter)	4221	MEN1	Pathogenic	2136134076	RCV002000025\|RCV002423132;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64574681	64574681	64574681	-
NM_001370259.2(MEN1):c.792C>G (p.Leu264=)	4221	MEN1	Likely benign	2136134213	RCV001410365\|RCV002420917;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64574683	64574683	64574683	-
NM_001370259.2(MEN1):c.792C>T (p.Leu264=)	4221	MEN1	Likely benign	2136134213	RCV002208835;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574683	64574683	64574683	-
NM_001370259.2(MEN1):c.791T>C (p.Leu264Pro)	4221	MEN1	Pathogenic	1941794175	RCV001211834;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574684	64574684	11:g.64574684A>G	-
NM_001370259.2(MEN1):c.788T>C (p.Leu263Pro)	4221	MEN1	Conflicting interpretations of pathogenicity	1114167502	RCV000491663\|RCV000811434;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574687	64574687	NC_000011.9:g.64574687A>G	ClinGen:CA381183996	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.786G>A (p.Lys262=)	4221	MEN1	Likely benign	-1	RCV002412271\|RCV003099766;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574689	64574689		-
NM_001370259.2(MEN1):c.785A>G (p.Lys262Arg)	4221	MEN1	Uncertain significance	1555165373	RCV000561461\|RCV000632100;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574690	64574690	NC_000011.9:g.64574690T>C	ClinGen:CA381184013	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.784-1G>C	4221	MEN1	Pathogenic/Likely pathogenic	1555165377	RCV000520872\|RCV000794756;	N	MedGen:CN517202\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574692	64574692	NC_000011.9:g.64574692C>G	ClinGen:CA381184025	CN517202 not provided;
NM_001370259.2(MEN1):c.784-1G>A	4221	MEN1	Likely pathogenic	1555165377	RCV001043139;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574692	64574692	11:g.64574692C>T	-
NM_001370259.2(MEN1):c.784-7C>G	4221	MEN1	Likely benign	1313431495	RCV001429713;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574698	64574698	64574698	-
NM_001370259.2(MEN1):c.784-7C>A	4221	MEN1	Likely benign	-1	RCV002801810;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574698	64574698	NC_000011.9:g.64574698G>T	-
NM_001370259.2(MEN1):c.784-8G>T	4221	MEN1	Likely benign	766553550	RCV002200169;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574699	64574699	64574699	-
NM_001370259.2(MEN1):c.784-8G>C	4221	MEN1	Likely benign	-1	RCV002862510;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574699	64574699	NC_000011.9:g.64574699C>G	-
NM_001370259.2(MEN1):c.784-9G>A	4221	MEN1	Pathogenic/Likely pathogenic	794728625	RCV000182415\|RCV000205749\|RCV002408796;	N	MedGen:C3661900\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64574700	64574700	NC_000011.9:g.64574700C>T	ClinGen:CA009635,OMIM:613733.0024	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.784-9G>C	4221	MEN1	Likely benign	794728625	RCV001392515;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574700	64574700	64574700	-
NM_001370259.2(MEN1):c.784-10C>T	4221	MEN1	Benign/Likely benign	71526470	RCV000475847\|RCV003387850;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:CN169374	11	64574701	64574701	NC_000011.9:g.64574701G>A	ClinGen:CA061567	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.784-10C>A	4221	MEN1	Uncertain significance	71526470	RCV000632083;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574701	64574701	NC_000011.9:g.64574701G>T	ClinGen:CA658797671	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.784-19TC[2]	4221	MEN1	Conflicting interpretations of pathogenicity	764290037	RCV000182400\|RCV000409712\|RCV001529754;	N	MedGen:CN169374\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:CN517202	11	64574705	64574706	NC_000011.9:g.64574706AG[2]	ClinGen:CA009629	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.784-16C>T	4221	MEN1	Likely benign	754257177	RCV000662550;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574707	64574707	11:g.64574707G>A	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.784-16C>G	4221	MEN1	Likely benign	754257177	RCV002200367;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574707	64574707	64574707	-
NM_001370259.2(MEN1):c.784-18C>G	4221	MEN1	Likely benign	-1	RCV003035135;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64574709	64574709	NC_000011.9:g.64574709G>C	-
NM_001370259.2(MEN1):c.784-129T>A	4221	MEN1	Benign/Likely benign	536461697	RCV002155423\|RCV003233039;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0054601,MedGen:C4539685,OMIM:617540	11	64574820	64574820	64574820	-
NM_001370259.2(MEN1):c.783+16A>G	4221	MEN1	Likely benign	-1	RCV002838016;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575008	64575008	NC_000011.9:g.64575008T>C	-
NM_001370259.2(MEN1):c.783+10G>C	4221	MEN1	Likely benign	2136139524	RCV001496763;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575014	64575014	64575014	-
NM_001370259.2(MEN1):c.783+8C>A	4221	MEN1	Likely benign	2136139552	RCV002155143;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575016	64575016	64575016	-
NM_001370259.2(MEN1):c.783+7G>A	4221	MEN1	Likely benign	1060503793	RCV001417870;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575017	64575017	NC_000011.9:g.64575017C>T	ClinGen:CA16613411	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.783+5G>T	4221	MEN1	Uncertain significance	1592648530	RCV001041154;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575019	64575019	11:g.64575019C>A	-
NM_001370259.2(MEN1):c.783+3G>A	4221	MEN1	Likely benign	-1	RCV002412119\|RCV003099758;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575021	64575021	64575021	-
NM_001370259.2(MEN1):c.783+2del	4221	MEN1	Likely pathogenic	-1	RCV002797049;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575022	64575022	NC_000011.9:g.64575022del	-
NM_001370259.2(MEN1):c.783+1G>A	4221	MEN1	Pathogenic	794728652	RCV000491531\|RCV000515529\|RCV000506752\|RCV000697334;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|\|MedGen:CN169374\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575023	64575023	NC_000011.9:g.64575023C>T	ClinGen:CA381184101	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.783+1G>C	4221	MEN1	Pathogenic	794728652	RCV001000126\|RCV002409331;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575023	64575023	11:g.64575023C>G	-
NM_001370259.2(MEN1):c.770TGCAGC[3] (p.257LQ[3])	4221	MEN1	Likely pathogenic	1555165485	RCV000632129;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575025	64575026	NC_000011.9:g.64575027CTGCAG[3]	ClinGen:CA658797672,OMIM:613733.0030	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.781C>T (p.Gln261Ter)	4221	MEN1	Pathogenic	1057520733	RCV000419478\|RCV000554384\|RCV002411313;	N	MedGen:C3661900\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575026	64575026	11:g.64575026G>A	ClinGen:CA16606275	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.778C>T (p.Gln260Ter)	4221	MEN1	Pathogenic	104894266	RCV000018170\|RCV000491298;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575029	64575029	11:g.64575029G>A	ClinGen:CA009615,OMIM:613733.0014	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.778C>G (p.Gln260Glu)	4221	MEN1	Uncertain significance	104894266	RCV001885690;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575029	64575029	64575029	-
NM_001370259.2(MEN1):c.777G>A (p.Leu259=)	4221	MEN1	Likely benign	2136139885	RCV002166589;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575030	64575030	64575030	-
NM_001370259.2(MEN1):c.774G>C (p.Gln258His)	4221	MEN1	Conflicting interpretations of pathogenicity	374659656	RCV000034788\|RCV000379424\|RCV000463800\|RCV000573824;	N	MedGen:C3661900\|Human Phenotype Ontology:HP:0000843,MONDO:MONDO:0001741,MedGen:C0020502\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575033	64575033	11:g.64575033C>G	ClinGen:CA009610	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.773A>G (p.Gln258Arg)	4221	MEN1	Uncertain significance	-1	RCV002301732;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575034	64575034	64575034	-
NM_001370259.2(MEN1):c.772C>T (p.Gln258Ter)	4221	MEN1	Pathogenic	886039416	RCV000255776\|RCV000632105;	N	MedGen:CN517202\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575035	64575035	11:g.64575035G>A	ClinGen:CA10588531	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.772C>G (p.Gln258Glu)	4221	MEN1	Uncertain significance	886039416	RCV000690002\|RCV001026760;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575035	64575035	NC_000011.9:g.64575035G>C	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.762_768dup (p.Leu257fs)	4221	MEN1	Likely pathogenic	1555165488	RCV000664332;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575038	64575039	NC_000011.9:g.64575040_64575046dup	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.769C>T (p.Leu257=)	4221	MEN1	Likely benign	-1	RCV002400556\|RCV003099718;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575038	64575038		-
NM_001370259.2(MEN1):c.766C>T (p.Leu256Phe)	4221	MEN1	Pathogenic/Likely pathogenic	878855198	RCV000234599\|RCV001269984;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:CN517202	11	64575041	64575041	NC_000011.9:g.64575041G>A	ClinGen:CA10582938	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.763G>A (p.Glu255Lys)	4221	MEN1	Uncertain significance	104894268	RCV000018176\|RCV001753420;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:CN517202	11	64575044	64575044	11:g.64575044C>T	ClinGen:CA009605,UniProtKB:O00255#VAR_005448,OMIM:613733.0020	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.763G>C (p.Glu255Gln)	4221	MEN1	Conflicting interpretations of pathogenicity	104894268	RCV000541629\|RCV000757459;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:CN517202	11	64575044	64575044	NC_000011.9:g.64575044C>G	ClinGen:CA381184221	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.762G>A (p.Leu254=)	4221	MEN1	Conflicting interpretations of pathogenicity	199909967	RCV000196618\|RCV000491869\|RCV001092063\|RCV001103406\|RCV002271458;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900\|Human Phenotype Ontology:HP:0000843,MONDO:MONDO:0001741,MedGen:C0020502\|MedGen:CN169374	11	64575045	64575045	NC_000011.9:g.64575045C>T	ClinGen:CA061523	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.761T>C (p.Leu254Pro)	4221	MEN1	Uncertain significance	-1	RCV002297105;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575046	64575046	64575046	-
NM_001370259.2(MEN1):c.760C>T (p.Leu254=)	4221	MEN1	Likely benign	1194394888	RCV000891026\|RCV001026620;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575047	64575047	11:g.64575047G>A	-
NM_001370259.2(MEN1):c.759G>T (p.Ser253=)	4221	MEN1	Likely benign	201829546	RCV000199841\|RCV000568935;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575048	64575048	11:g.64575048C>A	ClinGen:CA061514	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.759G>A (p.Ser253=)	4221	MEN1	Benign/Likely benign	201829546	RCV000231807\|RCV001026605;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575048	64575048	NC_000011.9:g.64575048C>T	ClinGen:CA061508	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.758C>A (p.Ser253Ter)	4221	MEN1	Likely pathogenic	386134259	RCV000030209;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575049	64575049	11:g.64575049G>T	ClinGen:CA009595	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.758C>T (p.Ser253Leu)	4221	MEN1	Conflicting interpretations of pathogenicity	386134259	RCV000491434\|RCV000460727\|RCV002253274;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900	11	64575049	64575049	NC_000011.9:g.64575049G>A	ClinGen:CA009601	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.758C>G (p.Ser253Trp)	4221	MEN1	Pathogenic	386134259	RCV000470590;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575049	64575049	NC_000011.9:g.64575049G>C	ClinGen:CA16613469	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.758del (p.Ser253fs)	4221	MEN1	Pathogenic	1592648765	RCV000800811;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575049	64575049	11:g.64575049_64575049del	-
NM_001370259.2(MEN1):c.756C>T (p.Asp252=)	4221	MEN1	Likely benign	-1	RCV002394067\|RCV003103415;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575051	64575051		-
NM_001370259.2(MEN1):c.754G>T (p.Asp252Tyr)	4221	MEN1	Conflicting interpretations of pathogenicity	770368608	RCV000228896\|RCV002392720\|RCV003401188;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|	11	64575053	64575053	11:g.64575053C>A	ClinGen:CA061503	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.754G>C (p.Asp252His)	4221	MEN1	Uncertain significance	770368608	RCV000704960\|RCV001026555;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575053	64575053	NC_000011.9:g.64575053C>G	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.754G>A (p.Asp252Asn)	4221	MEN1	Uncertain significance	770368608	RCV001026554\|RCV001204488;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575053	64575053	11:g.64575053C>T	-
NM_001370259.2(MEN1):c.753C>T (p.Thr251=)	4221	MEN1	Conflicting interpretations of pathogenicity	763326062	RCV000491168\|RCV000828127\|RCV001086629\|RCV001105326;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|Human Phenotype Ontology:HP:0000843,MONDO:MONDO:0001741,MedGen:C0020502	11	64575054	64575054	NC_000011.9:g.64575054G>A	ClinGen:CA061487	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.751A>G (p.Thr251Ala)	4221	MEN1	Uncertain significance	-1	RCV003470096;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575056	64575056		-
NM_001370259.2(MEN1):c.746_749dup (p.Thr251fs)	4221	MEN1	Pathogenic	1592648830	RCV000796395;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575057	64575058	11:g.64575057_64575058insTGCA	-
NM_001370259.2(MEN1):c.746T>A (p.Leu249Gln)	4221	MEN1	Uncertain significance	1824195184	RCV001340765;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575061	64575061	64575061	-
NM_001370259.2(MEN1):c.739_745del (p.Ile247fs)	4221	MEN1	Pathogenic	1555165503	RCV000524643;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575062	64575068	NC_000011.9:g.64575064_64575070del	ClinGen:CA658656173	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.745C>A (p.Leu249Met)	4221	MEN1	Uncertain significance	2136140837	RCV001985040;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575062	64575062	64575062	-
NM_001370259.2(MEN1):c.744C>T (p.Asp248=)	4221	MEN1	Likely benign	2136140889	RCV002104933;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575063	64575063	64575063	-
NM_001370259.2(MEN1):c.741T>C (p.Ile247=)	4221	MEN1	Likely benign	1592648877	RCV001460060;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575066	64575066	11:g.64575066A>G	-
NM_001370259.2(MEN1):c.740T>C (p.Ile247Thr)	4221	MEN1	Uncertain significance	1043531053	RCV001026403\|RCV001053547\|RCV003238272;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900	11	64575067	64575067	11:g.64575067A>G	-
NM_001370259.2(MEN1):c.739dup (p.Ile247fs)	4221	MEN1	Pathogenic	2136141104	RCV001387835;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575067	64575068	64575067	-
NM_001370259.2(MEN1):c.739A>G (p.Ile247Val)	4221	MEN1	Uncertain significance	1555165508	RCV000632132;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575068	64575068	NC_000011.9:g.64575068T>C	ClinGen:CA381184355	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.736T>G (p.Ser246Ala)	4221	MEN1	Uncertain significance	1175283759	RCV000548928\|RCV003159749;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575071	64575071	NC_000011.9:g.64575071A>C	ClinGen:CA381184371	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.734del (p.Pro245fs)	4221	MEN1	Pathogenic	1565646772	RCV000761296;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575073	64575073	NC_000011.9:g.64575075del	-
NM_001370259.2(MEN1):c.733C>G (p.Pro245Ala)	4221	MEN1	Uncertain significance	1373521153	RCV001230337;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575074	64575074	11:g.64575074G>C	-
NM_001370259.2(MEN1):c.729C>T (p.Ile243=)	4221	MEN1	Likely benign	1353237754	RCV000536420\|RCV003159748;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575078	64575078	NC_000011.9:g.64575078G>A	ClinGen:CA474983796	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.726C>T (p.Ala242=)	4221	MEN1	Likely benign	1198651608	RCV000528262\|RCV002384058;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575081	64575081	11:g.64575081G>A	ClinGen:CA474983798	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.725C>T (p.Ala242Val)	4221	MEN1	Pathogenic/Likely pathogenic	2136141530	RCV001378938;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575082	64575082	64575082	-
NM_001370259.2(MEN1):c.723_724del (p.Ala242fs)	4221	MEN1	Pathogenic	1592649069	RCV001026184\|RCV001862359;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575083	64575084	11:g.64575083_64575084del	-
NM_001370259.2(MEN1):c.722G>A (p.Cys241Tyr)	4221	MEN1	Pathogenic/Likely pathogenic	794728624	RCV000461795\|RCV000491344\|RCV001812172;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	11	64575085	64575085	NC_000011.9:g.64575085C>T	ClinGen:CA009579	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.721T>C (p.Cys241Arg)	4221	MEN1	Likely pathogenic	1592649108	RCV000816677\|RCV002293487\|RCV002372308;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575086	64575086	11:g.64575086A>G	-
NM_001370259.2(MEN1):c.720G>T (p.Val240=)	4221	MEN1	Likely benign	1555165534	RCV000547687;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575087	64575087	NC_000011.9:g.64575087C>A	ClinGen:CA474983804	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.716T>C (p.Met239Thr)	4221	MEN1	Uncertain significance	1441995061	RCV001026113\|RCV002551949;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575091	64575091	11:g.64575091A>G	-
NM_001370259.2(MEN1):c.711G>A (p.Ala237=)	4221	MEN1	Likely benign	144677807	RCV000465578\|RCV000562651;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575096	64575096	NC_000011.9:g.64575096C>T	ClinGen:CA061472	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.710C>T (p.Ala237Val)	4221	MEN1	Uncertain significance	760289964	RCV000465273\|RCV001026052;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575097	64575097	NC_000011.9:g.64575097G>A	ClinGen:CA061467	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.706G>T (p.Val236Leu)	4221	MEN1	Uncertain significance	-1	RCV002829721;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575101	64575101	NC_000011.9:g.64575101C>A	-
NM_001370259.2(MEN1):c.702G>A (p.Met234Ile)	4221	MEN1	Uncertain significance	1448041546	RCV000632103\|RCV003302991;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575105	64575105	NC_000011.9:g.64575105C>T	ClinGen:CA381184587	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.700A>T (p.Met234Leu)	4221	MEN1	Uncertain significance	1296948476	RCV001217728;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575107	64575107	11:g.64575107T>A	-
NM_001370259.2(MEN1):c.700A>G (p.Met234Val)	4221	MEN1	Uncertain significance	-1	RCV002659365;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575107	64575107	NC_000011.9:g.64575107T>C	-
NM_001370259.2(MEN1):c.698A>C (p.Lys233Thr)	4221	MEN1	Uncertain significance	1592649270	RCV000812047;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575109	64575109	11:g.64575109T>G	-
NM_001370259.2(MEN1):c.697A>C (p.Lys233Gln)	4221	MEN1	Uncertain significance	-1	RCV002362542\|RCV003098432;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575110	64575110	64575110	-
NM_001370259.2(MEN1):c.696C>T (p.Arg232=)	4221	MEN1	Conflicting interpretations of pathogenicity	753411991	RCV000813377\|RCV003166322;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575111	64575111	11:g.64575111G>A	-
NM_001370259.2(MEN1):c.695G>A (p.Arg232His)	4221	MEN1	Uncertain significance	1941826992	RCV001042600;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575112	64575112	11:g.64575112C>T	-
NM_001370259.2(MEN1):c.694C>T (p.Arg232Cys)	4221	MEN1	Conflicting interpretations of pathogenicity	1225847249	RCV000536638\|RCV001025835;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575113	64575113	NC_000011.9:g.64575113G>A	ClinGen:CA381184625	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.693C>T (p.Asp231=)	4221	MEN1	Likely benign	-1	RCV002362416\|RCV003098423;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575114	64575114		-
NM_001370259.2(MEN1):c.691G>C (p.Asp231His)	4221	MEN1	Uncertain significance	1941827572	RCV001056867\|RCV002374934;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575116	64575116	11:g.64575116C>G	-
NM_001370259.2(MEN1):c.690T>C (p.Cys230=)	4221	MEN1	Likely benign	2136142487	RCV002151686;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575117	64575117	64575117	-
NC_000011.9:g.(?_64575120)_(64576450_?)del	4221	MEN1	Pathogenic	-1	RCV003123031;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575120	64576450		-
NM_001370259.2(MEN1):c.686G>A (p.Arg229His)	4221	MEN1	Conflicting interpretations of pathogenicity	878855197	RCV000233998\|RCV001025749\|RCV002469085;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN169374	11	64575121	64575121	NC_000011.9:g.64575121C>T	ClinGen:CA10582939	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.682_685dup (p.Arg229fs)	4221	MEN1	Pathogenic	1114167519	RCV000491507\|RCV001229546;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575121	64575122	NC_000011.9:g.64575123_64575126dup	ClinGen:CA645369567	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.685C>T (p.Arg229Cys)	4221	MEN1	Conflicting interpretations of pathogenicity	754378887	RCV000196791\|RCV001025738\|RCV001795326;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	11	64575122	64575122	11:g.64575122G>A	ClinGen:CA061444	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.685C>A (p.Arg229Ser)	4221	MEN1	Uncertain significance	754378887	RCV001364494;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575122	64575122	64575122	-
NM_001370259.2(MEN1):c.682A>G (p.Met228Val)	4221	MEN1	Uncertain significance	1060499982	RCV000476428\|RCV001025697\|RCV003401443;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|	11	64575125	64575125	NC_000011.9:g.64575125T>C	ClinGen:CA16613629	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.681C>A (p.Tyr227Ter)	4221	MEN1	Pathogenic	778921501	RCV000560572\|RCV001269815;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:CN517202	11	64575126	64575126	NC_000011.9:g.64575126G>T	ClinGen:CA381184686	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.681C>T (p.Tyr227=)	4221	MEN1	Likely benign	778921501	RCV001532640\|RCV001417430\|RCV002368305;	N	MedGen:C3661900\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575126	64575126	64575126	-
NM_001370259.2(MEN1):c.676T>G (p.Ser226Ala)	4221	MEN1	Uncertain significance	-1	RCV002295122;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575131	64575131	64575131	-
NM_001370259.2(MEN1):c.669G>A (p.Leu223=)	4221	MEN1	Likely benign	2136143050	RCV001412353;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575138	64575138	64575138	-
NM_001370259.2(MEN1):c.668T>C (p.Leu223Pro)	4221	MEN1	Pathogenic	886039415	RCV000255095\|RCV000491535\|RCV001235431;	N	MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575139	64575139	11:g.64575139A>G	ClinGen:CA10588532	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.667C>T (p.Leu223=)	4221	MEN1	Likely benign	1592649487	RCV001431499;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575140	64575140	11:g.64575140G>A	-
NM_001370259.2(MEN1):c.666C>T (p.Tyr222=)	4221	MEN1	Likely benign	1555165597	RCV002184066\|RCV002363699;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575141	64575141	64575141	-
NM_001370259.2(MEN1):c.665A>C (p.Tyr222Ser)	4221	MEN1	Uncertain significance	1555165601	RCV000632115;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575142	64575142	11:g.64575142T>G	ClinGen:CA381185215	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.664T>G (p.Tyr222Asp)	4221	MEN1	Uncertain significance	1941830592	RCV001347617;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575143	64575143	64575143	-
NM_001370259.2(MEN1):c.663G>C (p.Leu221=)	4221	MEN1	Likely benign	1466764986	RCV001506095;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575144	64575144	64575144	-
NM_001370259.2(MEN1):c.662T>C (p.Leu221Pro)	4221	MEN1	Conflicting interpretations of pathogenicity	2136143369	RCV001896354\|RCV002361181;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575145	64575145	64575145	-
NM_001370259.2(MEN1):c.660G>A (p.Trp220Ter)	4221	MEN1	Pathogenic	886039414	RCV000256041\|RCV000490921\|RCV001224068;	N	MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575147	64575147	11:g.64575147C>T	ClinGen:CA10588533	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.660G>T (p.Trp220Cys)	4221	MEN1	Uncertain significance	886039414	RCV000704895;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575147	64575147	NC_000011.9:g.64575147C>A	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.659G>A (p.Trp220Ter)	4221	MEN1	Pathogenic	1565647197	RCV000696600;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575148	64575148	NC_000011.9:g.64575148C>T	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.655-15_658del	4221	MEN1	Likely pathogenic	1592649598	RCV000823354;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575149	64575167	11:g.64575149_64575167del	-
NM_001370259.2(MEN1):c.657C>T (p.Ser219=)	4221	MEN1	Likely benign	2059889716	RCV001394944\|RCV003284300;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575150	64575150	64575150	-
NM_001370259.2(MEN1):c.655-1G>A	4221	MEN1	Pathogenic	1592649615	RCV000819459;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575153	64575153	11:g.64575153C>T	-
NM_001370259.2(MEN1):c.655-1G>C	4221	MEN1	Pathogenic/Likely pathogenic	1592649615	RCV001025404\|RCV002281151\|RCV001862323;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575153	64575153	11:g.64575153C>G	-
NM_001370259.2(MEN1):c.655-2A>G	4221	MEN1	Pathogenic	-1	RCV003084888;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575154	64575154	NC_000011.9:g.64575154T>C	-
NM_001370259.2(MEN1):c.655-7_655-4dup	4221	MEN1	Likely benign	2136143779	RCV001426737;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575155	64575156	64575155	-
NM_001370259.2(MEN1):c.655-4del	4221	MEN1	Conflicting interpretations of pathogenicity	748005956	RCV000234359\|RCV000454942\|RCV000566396;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:CN169374\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575156	64575156	NC_000011.9:g.64575156del	ClinGen:CA061415	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.655-5dup	4221	MEN1	Conflicting interpretations of pathogenicity	772016629	RCV000411902\|RCV001706621\|RCV002256225\|RCV003321585;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN169374	11	64575156	64575157	NC_000011.9:g.64575163dup	ClinGen:CA6082226	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.655-6_655-4del	4221	MEN1	Uncertain significance	1555165623	RCV000632098;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575156	64575158	NC_000011.9:g.64575156_64575158del	ClinGen:CA658797673	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.655-5C>G	4221	MEN1	Conflicting interpretations of pathogenicity	752563214	RCV000227150\|RCV002365218\|RCV003226264;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN169374	11	64575157	64575157	NC_000011.9:g.64575157G>C	ClinGen:CA061418	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.655-5C>A	4221	MEN1	Uncertain significance	752563214	RCV001025408\|RCV001068075;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575157	64575157	11:g.64575157G>T	-
NM_001370259.2(MEN1):c.655-5del	4221	MEN1	Benign/Likely benign	772016629	RCV002164791\|RCV003222384;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900	11	64575157	64575157	64575156	-
NM_001370259.2(MEN1):c.655-5C>T	4221	MEN1	Likely benign	752563214	RCV002220890;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575157	64575157	64575157	-
NM_001370259.2(MEN1):c.655-6C>T	4221	MEN1	Conflicting interpretations of pathogenicity	77461664	RCV000679258\|RCV001082522\|RCV001105327\|RCV001731368\|RCV002255283;	N	MedGen:C3661900\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|Human Phenotype Ontology:HP:0000843,MONDO:MONDO:0001741,MedGen:C0020502\|MedGen:CN169374\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575158	64575158	11:g.64575158G>A	ClinGen:CA009562	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.655-6C>A	4221	MEN1	Conflicting interpretations of pathogenicity	77461664	RCV000454964\|RCV000657085\|RCV000988573\|RCV002257506;	N	MedGen:CN169374\|MedGen:C3661900\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575158	64575158	11:g.64575158G>T	ClinGen:CA061426	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.655-6C>G	4221	MEN1	Conflicting interpretations of pathogenicity	77461664	RCV000231039\|RCV000604145\|RCV001105328\|RCV002256173;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:CN169374\|Human Phenotype Ontology:HP:0000843,MONDO:MONDO:0001741,MedGen:C0020502\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575158	64575158	NC_000011.9:g.64575158G>C	ClinGen:CA061430	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.655-7C>A	4221	MEN1	Uncertain significance	771297371	RCV000547893;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575159	64575159	11:g.64575159G>T	ClinGen:CA061437	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.655-7C>G	4221	MEN1	Uncertain significance	771297371	RCV001369936;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575159	64575159	64575159	-
NM_001370259.2(MEN1):c.655-7C>T	4221	MEN1	Likely benign	771297371	RCV001439761;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575159	64575159	64575159	-
NM_001370259.2(MEN1):c.655-8C>T	4221	MEN1	Likely benign	2136143989	RCV002218698;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575160	64575160	64575160	-
NM_001370259.2(MEN1):c.655-9C>A	4221	MEN1	Uncertain significance	2136144016	RCV002037070;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575161	64575161	64575161	-
NM_001370259.2(MEN1):c.655-10C>T	4221	MEN1	Likely benign	2136144068	RCV002165957;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575162	64575162	64575162	-
NM_001370259.2(MEN1):c.655-12dup	4221	MEN1	Likely benign	2136144164	RCV002218015;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575163	64575164	64575163	-
NM_001370259.2(MEN1):c.655-11C>T	4221	MEN1	Likely benign	781234614	RCV002212281;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575163	64575163	64575163	-
NM_001370259.2(MEN1):c.655-11C>G	4221	MEN1	Likely benign	781234614	RCV002157457;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575163	64575163	64575163	-
NM_001370259.2(MEN1):c.655-12T>C	4221	MEN1	Likely benign	2136144144	RCV002128038;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575164	64575164	64575164	-
NM_001370259.2(MEN1):c.655-19_655-17del	4221	MEN1	Likely benign	2136144272	RCV002111496;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575169	64575171	64575168	-
NM_001370259.2(MEN1):c.655-19G>A	4221	MEN1	Likely benign	-1	RCV002586510;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575171	64575171	NC_000011.9:g.64575171C>T	-
NM_001370259.2(MEN1):c.654+18dup	4221	MEN1	Benign	112700230	RCV002102849;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575344	64575345	64575344	-
NM_001370259.2(MEN1):c.654+18C>T	4221	MEN1	Conflicting interpretations of pathogenicity	180737290	RCV000030208\|RCV000606793;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:CN169374	11	64575345	64575345	11:g.64575345G>A	ClinGen:CA009555	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.654+18C>G	4221	MEN1	Likely benign	180737290	RCV002168552;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575345	64575345	64575345	-
NM_001370259.2(MEN1):c.654+18del	4221	MEN1	Benign	112700230	RCV002124958;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575345	64575345	64575344	-
NM_001370259.2(MEN1):c.654+18C>A	4221	MEN1	Likely benign	-1	RCV002995996;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575345	64575345	NC_000011.9:g.64575345G>T	-
NM_001370259.2(MEN1):c.654+17C>G	4221	MEN1	Likely benign	764070489	RCV002085395;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575346	64575346	64575346	-
NM_001370259.2(MEN1):c.654+17C>A	4221	MEN1	Likely benign	-1	RCV002670976;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575346	64575346	NC_000011.9:g.64575346G>T	-
NM_001370259.2(MEN1):c.654+16C>A	4221	MEN1	Likely benign	2136147604	RCV002143615;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575347	64575347	64575347	-
NM_001370259.2(MEN1):c.654+15C>G	4221	MEN1	Likely benign	1262314762	RCV002218109;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575348	64575348	64575348	-
NM_001370259.2(MEN1):c.654+14C>T	4221	MEN1	Likely benign	-1	RCV003040075;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575349	64575349	NC_000011.9:g.64575349G>A	-
NM_001370259.2(MEN1):c.654+11C>T	4221	MEN1	Likely benign	1941846380	RCV002200254;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575352	64575352	64575352	-
NM_001370259.2(MEN1):c.654+10C>T	4221	MEN1	Likely benign	921850475	RCV000461965;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575353	64575353	NC_000011.9:g.64575353G>A	ClinGen:CA16613630	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.654+10C>A	4221	MEN1	Likely benign	921850475	RCV001445117;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575353	64575353	64575353	-
NM_001370259.2(MEN1):c.654+9C>T	4221	MEN1	Likely benign	202134234	RCV000461750;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575354	64575354	NC_000011.9:g.64575354G>A	ClinGen:CA061381	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.654+9C>A	4221	MEN1	Likely benign	202134234	RCV000632159;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575354	64575354	NC_000011.9:g.64575354G>T	ClinGen:CA658797675	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.654+9C>G	4221	MEN1	Likely benign	202134234	RCV000632169;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575354	64575354	11:g.64575354G>C	ClinGen:CA658797674	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.654+6G>T	4221	MEN1	Uncertain significance	1941847253	RCV001221549;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575357	64575357	11:g.64575357C>A	-
NM_001370259.2(MEN1):c.654+5T>C	4221	MEN1	Conflicting interpretations of pathogenicity	757049384	RCV001056574\|RCV002365715;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575358	64575358	11:g.64575358A>G	-
NM_001370259.2(MEN1):c.654+4T>C	4221	MEN1	Uncertain significance	1941847622	RCV001036068;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575359	64575359	11:g.64575359A>G	-
NM_001370259.2(MEN1):c.654+3A>G	4221	MEN1	Likely pathogenic	1064793168	RCV001061257;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575360	64575360	11:g.64575360T>C	-
NM_001370259.2(MEN1):c.649_654+2del	4221	MEN1	Likely pathogenic	386134258	RCV000030207;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575361	64575368	11:g.64575361_64575368del	ClinGen:CA260470	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.654+1G>A	4221	MEN1	Pathogenic	794728622	RCV000032982\|RCV002362604\|RCV002510773;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	11	64575362	64575362	11:g.64575362C>T	OMIM:613733.0035	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.654+1G>T	4221	MEN1	Pathogenic	794728622	RCV000182411\|RCV000709159\|RCV002362934;	N	MedGen:C3661900\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575362	64575362	NC_000011.9:g.64575362C>A	ClinGen:CA009560	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.653G>A (p.Arg218Gln)	4221	MEN1	Uncertain significance	1423517569	RCV001025386\|RCV001056016;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575364	64575364	11:g.64575364C>T	-
NM_001370259.2(MEN1):c.653G>C (p.Arg218Pro)	4221	MEN1	Uncertain significance	1423517569	RCV001212796;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575364	64575364	11:g.64575364C>G	-
NM_001370259.2(MEN1):c.644_652delinsGCCCCT (p.Val215_Arg218delinsGlyProTrp)	4221	MEN1	Uncertain significance	386134257	RCV000030206\|RCV000722116;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:CN169374	11	64575365	64575373	11:g.64575366_64575373del	ClinGen:CA009539	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.652C>T (p.Arg218Trp)	4221	MEN1	Uncertain significance	794728620	RCV000410087\|RCV001818447\|RCV002362933;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:CN169374\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575365	64575365	11:g.64575365G>A	ClinGen:CA009550	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.652C>A (p.Arg218=)	4221	MEN1	Likely benign	794728620	RCV001448064;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575365	64575365	64575365	-
NM_001370259.2(MEN1):c.647C>T (p.Ala216Val)	4221	MEN1	Uncertain significance	2136148590	RCV001993765;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575370	64575370	64575370	-
NM_001370259.2(MEN1):c.646G>C (p.Ala216Pro)	4221	MEN1	Uncertain significance	1592650523	RCV000802474;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575371	64575371	11:g.64575371C>G	-
NM_001370259.2(MEN1):c.646del (p.Ala216fs)	4221	MEN1	Pathogenic	2136148702	RCV001894281;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575371	64575371	64575370	-
NM_001370259.2(MEN1):c.645G>A (p.Val215=)	4221	MEN1	Conflicting interpretations of pathogenicity	1347044526	RCV001365237\|RCV002255652;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575372	64575372	64575372	-
NM_001370259.2(MEN1):c.643G>A (p.Val215Met)	4221	MEN1	Pathogenic/Likely pathogenic	794728621	RCV000230442\|RCV001797061;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900	11	64575374	64575374	11:g.64575374C>T	ClinGen:CA009535	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.642T>C (p.Gly214=)	4221	MEN1	Likely benign	931878410	RCV001479044\|RCV002363263;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575375	64575375	11:g.64575375A>G	-
NM_001370259.2(MEN1):c.641G>C (p.Gly214Ala)	4221	MEN1	Uncertain significance	2136148915	RCV002025366;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575376	64575376	64575376	-
NM_001370259.2(MEN1):c.640G>A (p.Gly214Ser)	4221	MEN1	Uncertain significance	781493730	RCV000205360\|RCV001025237\|RCV003237765;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	11	64575377	64575377	NC_000011.9:g.64575377C>T	ClinGen:CA061345	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.640G>T (p.Gly214Cys)	4221	MEN1	Uncertain significance	781493730	RCV001991237;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575377	64575377	64575377	-
NM_001370259.2(MEN1):c.639C>T (p.Ala213=)	4221	MEN1	Likely benign	746067825	RCV000227531\|RCV000562641;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575378	64575378	NC_000011.9:g.64575378G>A	ClinGen:CA061341	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.638_639delinsAA (p.Ala213Glu)	4221	MEN1	Uncertain significance	1114167518	RCV000491024\|RCV002527050\|RCV003235248;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:CN169374	11	64575378	64575379	NC_000011.9:g.64575378_64575379delinsTT	ClinGen:CA645369568	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.639C>A (p.Ala213=)	4221	MEN1	Likely benign	746067825	RCV001399750;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575378	64575378	11:g.64575378G>T	-
NM_001370259.2(MEN1):c.639del (p.Gly214fs)	4221	MEN1	Pathogenic	1941850919	RCV001056652;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575378	64575378	11:g.64575378_64575378del	-
NM_001370259.2(MEN1):c.638C>G (p.Ala213Gly)	4221	MEN1	Uncertain significance	-1	RCV003470099;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575379	64575379		-
NM_001370259.2(MEN1):c.637G>A (p.Ala213Thr)	4221	MEN1	Uncertain significance	-1	RCV002979145;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575380	64575380	NC_000011.9:g.64575380C>T	-
NM_001370259.2(MEN1):c.635A>G (p.Asn212Ser)	4221	MEN1	Uncertain significance	1438685841	RCV000632102\|RCV002248834\|RCV002360516\|RCV002510940;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:CN169374\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	11	64575382	64575382	11:g.64575382T>C	ClinGen:CA381185348	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.631_634del (p.Val211fs)	4221	MEN1	Pathogenic	1941851693	RCV000018182;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575383	64575386	NC_000011.9:g.64575385_64575388del	OMIM:613733.0026	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.634A>G (p.Asn212Asp)	4221	MEN1	Uncertain significance	1060499980	RCV000472651;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575383	64575383	NC_000011.9:g.64575383T>C	ClinGen:CA16613421	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.633del (p.Asn212fs)	4221	MEN1	Pathogenic	878855196	RCV000232633;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575384	64575384	NC_000011.9:g.64575384del	ClinGen:CA10582940	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.632T>G (p.Val211Gly)	4221	MEN1	Uncertain significance	1565647698	RCV000685919;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575385	64575385	NC_000011.9:g.64575385A>C	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.628_631del (p.Thr210fs)	4221	MEN1	Pathogenic	794728640	RCV000018163\|RCV000182437\|RCV000491752;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575386	64575389	NC_000011.9:g.64575389_64575392del	ClinGen:CA009530,OMIM:613733.0007	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.630A>C (p.Thr210=)	4221	MEN1	Likely benign	1592650685	RCV001505443;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575387	64575387	11:g.64575387T>G	-
NM_001370259.2(MEN1):c.629C>G (p.Thr210Arg)	4221	MEN1	Uncertain significance	756287855	RCV000471586;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575388	64575388	NC_000011.9:g.64575388G>C	ClinGen:CA16613473	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.629C>A (p.Thr210Lys)	4221	MEN1	Uncertain significance	756287855	RCV001991172\|RCV003170340;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575388	64575388	64575388	-
NM_001370259.2(MEN1):c.627G>C (p.Gln209His)	4221	MEN1	Uncertain significance	1565647751	RCV000694820;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575390	64575390	11:g.64575390C>G	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.627G>T (p.Gln209His)	4221	MEN1	Uncertain significance	1565647751	RCV001343884;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575390	64575390	64575390	-
NM_001370259.2(MEN1):c.627G>A (p.Gln209=)	4221	MEN1	Likely benign	1565647751	RCV001421353;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575390	64575390	64575390	-
NM_001370259.2(MEN1):c.625C>T (p.Gln209Ter)	4221	MEN1	Pathogenic	1565647767	RCV000692015;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575392	64575392	NC_000011.9:g.64575392G>A	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.621G>A (p.Arg207=)	4221	MEN1	Likely benign	779966911	RCV001487021\|RCV002363025;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575396	64575396	11:g.64575396C>T	ClinGen:CA061329	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.619A>G (p.Arg207Gly)	4221	MEN1	Uncertain significance	1941853632	RCV001212253\|RCV002365954;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575398	64575398	11:g.64575398T>C	-
NM_001370259.2(MEN1):c.618C>T (p.Arg206=)	4221	MEN1	Uncertain significance	1555165717	RCV000559647;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575399	64575399	11:g.64575399G>A	ClinGen:CA475162852	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.617G>A (p.Arg206His)	4221	MEN1	Uncertain significance	1565647825	RCV000697796\|RCV002352168\|RCV003329327;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	11	64575400	64575400	NC_000011.9:g.64575400C>T	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.616C>T (p.Arg206Cys)	4221	MEN1	Uncertain significance	1392579402	RCV001316658\|RCV002357135;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575401	64575401	64575401	-
NM_001370259.2(MEN1):c.612G>C (p.Glu204Asp)	4221	MEN1	Uncertain significance	-1	RCV002300414;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575405	64575405	64575405	-
NM_001370259.2(MEN1):c.609C>T (p.Asn203=)	4221	MEN1	Likely benign	749844029	RCV000570189\|RCV000632152;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575408	64575408	11:g.64575408G>A	ClinGen:CA061316	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.609C>G (p.Asn203Lys)	4221	MEN1	Uncertain significance	749844029	RCV002018265;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575408	64575408	64575408	-
NM_001370259.2(MEN1):c.606C>A (p.Gly202=)	4221	MEN1	Likely benign	-1	RCV002933713;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575411	64575411		-
NM_001370259.2(MEN1):c.605G>A (p.Gly202Asp)	4221	MEN1	Uncertain significance	1941854779	RCV001216886;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575412	64575412	11:g.64575412C>T	-
NM_001370259.2(MEN1):c.605del (p.Gly202fs)	4221	MEN1	Pathogenic	-1	RCV003450206;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575412	64575412		-
NM_001370259.2(MEN1):c.601A>G (p.Lys201Glu)	4221	MEN1	Uncertain significance	-1	RCV002993837;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575416	64575416	NC_000011.9:g.64575416T>C	-
NM_001370259.2(MEN1):c.598G>A (p.Gly200Ser)	4221	MEN1	Uncertain significance	1592650813	RCV000823899;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575419	64575419	11:g.64575419C>T	-
NM_001370259.2(MEN1):c.597C>T (p.His199=)	4221	MEN1	Benign/Likely benign	150512958	RCV000119192\|RCV000249354\|RCV000491834\|RCV001650974;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:CN169374\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	11	64575420	64575420	11:g.64575420G>A	ClinGen:CA009524	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.597C>A (p.His199Gln)	4221	MEN1	Uncertain significance	150512958	RCV000547248\|RCV002358449;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575420	64575420	11:g.64575420G>T	ClinGen:CA381185509	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.594G>A (p.Trp198Ter)	4221	MEN1	Pathogenic	104894257	RCV000632134\|RCV003317132;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:CN517202	11	64575423	64575423	NC_000011.9:g.64575423C>T	ClinGen:CA009518	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.593G>A (p.Trp198Ter)	4221	MEN1	Pathogenic	104894258	RCV000018162;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575424	64575424	11:g.64575424C>T	OMIM:613733.0006,ClinGen:CA009514	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.584_593del (p.Glu195fs)	4221	MEN1	Pathogenic	-1	RCV002736767;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575424	64575433	NC_000011.9:g.64575427_64575436del	-
NM_001370259.2(MEN1):c.591C>G (p.Thr197=)	4221	MEN1	Benign/Likely benign	527294715	RCV000123387\|RCV002354309;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575426	64575426	NC_000011.9:g.64575426G>C	ClinGen:CA009507	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.591C>T (p.Thr197=)	4221	MEN1	Likely benign	527294715	RCV002173888\|RCV002352927;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575426	64575426	64575426	-
NM_001370259.2(MEN1):c.590C>T (p.Thr197Ile)	4221	MEN1	Uncertain significance	1592650893	RCV000794077\|RCV003166114;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575427	64575427	11:g.64575427G>A	-
NM_001370259.2(MEN1):c.588C>T (p.Val196=)	4221	MEN1	Likely benign	1592650906	RCV001431451;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575429	64575429	11:g.64575429G>A	-
NM_001370259.2(MEN1):c.584_586del (p.Glu195del)	4221	MEN1	Uncertain significance	2136151782	RCV001533150;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575431	64575433	64575430	-
NM_001370259.2(MEN1):c.586G>A (p.Val196Ile)	4221	MEN1	Uncertain significance	2136151708	RCV002011495;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575431	64575431	64575431	-
NM_001370259.2(MEN1):c.585G>A (p.Glu195=)	4221	MEN1	Likely benign	864622177	RCV000204677;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575432	64575432	11:g.64575432C>T	ClinGen:CA348878	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.582T>G (p.Ala194=)	4221	MEN1	Likely benign	1592650942	RCV001403320;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575435	64575435	11:g.64575435A>C	-
NM_001370259.2(MEN1):c.582T>A (p.Ala194=)	4221	MEN1	Likely benign	1592650942	RCV001462864;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575435	64575435	64575435	-
NM_001370259.2(MEN1):c.581C>G (p.Ala194Gly)	4221	MEN1	Uncertain significance	2136152165	RCV002042560;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575436	64575436	64575436	-
NM_001370259.2(MEN1):c.579A>T (p.Thr193=)	4221	MEN1	Likely benign	-1	RCV002359802\|RCV003096876;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575438	64575438		-
NM_001370259.2(MEN1):c.578C>G (p.Thr193Arg)	4221	MEN1	Uncertain significance	1592650971	RCV000802976;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575439	64575439	11:g.64575439G>C	-
NM_001370259.2(MEN1):c.578C>T (p.Thr193Ile)	4221	MEN1	Uncertain significance	1592650971	RCV001340366;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575439	64575439	64575439	-
NM_001370259.2(MEN1):c.578C>A (p.Thr193Lys)	4221	MEN1	Uncertain significance	1592650971	RCV001959432;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575439	64575439	64575439	-
NM_001370259.2(MEN1):c.577A>G (p.Thr193Ala)	4221	MEN1	Uncertain significance	-1	RCV003470092;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575440	64575440		-
NM_001370259.2(MEN1):c.574C>T (p.Gln192Ter)	4221	MEN1	Pathogenic	-1	RCV003058326;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575443	64575443	NC_000011.9:g.64575443G>A	-
NM_001370259.2(MEN1):c.573G>T (p.Glu191Asp)	4221	MEN1	Uncertain significance	1592651018	RCV001024469\|RCV001862290;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575444	64575444	11:g.64575444C>A	-
NM_001370259.2(MEN1):c.573G>A (p.Glu191=)	4221	MEN1	Likely benign	1592651018	RCV002110099;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575444	64575444	64575444	-
NM_001370259.2(MEN1):c.570G>A (p.Gly190=)	4221	MEN1	Conflicting interpretations of pathogenicity	547249181	RCV000473714\|RCV000564641\|RCV001105329\|RCV001821300;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|Human Phenotype Ontology:HP:0000843,MONDO:MONDO:0001741,MedGen:C0020502\|MedGen:CN169374	11	64575447	64575447	NC_000011.9:g.64575447C>T	ClinGen:CA061297	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.569G>A (p.Gly190Glu)	4221	MEN1	Uncertain significance	878855195	RCV000229709;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575448	64575448	NC_000011.9:g.64575448C>T	ClinGen:CA10582941	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.568G>A (p.Gly190Arg)	4221	MEN1	Uncertain significance	1555165742	RCV000632127\|RCV001024412;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575449	64575449	NC_000011.9:g.64575449C>T	ClinGen:CA381185697	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.567T>A (p.Asn189Lys)	4221	MEN1	Uncertain significance	1212919060	RCV001315304;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575450	64575450	64575450	-
NM_001370259.2(MEN1):c.566A>G (p.Asn189Ser)	4221	MEN1	Conflicting interpretations of pathogenicity	587780844	RCV000123386\|RCV001024385\|RCV003153410;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	11	64575451	64575451	NC_000011.9:g.64575451T>C	ClinGen:CA009502	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.563_564del (p.Pro188fs)	4221	MEN1	Pathogenic	1555165756	RCV000529950\|RCV002350189;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575453	64575454	11:g.64575453_64575454del	ClinGen:CA658658066	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.563C>T (p.Pro188Leu)	4221	MEN1	Conflicting interpretations of pathogenicity	199706698	RCV000148613\|RCV000200394\|RCV000455592\|RCV000708708;	N	Human Phenotype Ontology:HP:0000843,MONDO:MONDO:0001741,MedGen:C0020502\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:CN169374\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575454	64575454	11:g.64575454G>A	ClinGen:CA009496	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.562C>T (p.Pro188Ser)	4221	MEN1	Uncertain significance	1209606579	RCV002036732\|RCV002346333;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575455	64575455	64575455	-
NM_001370259.2(MEN1):c.555G>T (p.Val185=)	4221	MEN1	Likely benign	1178007625	RCV002087434;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575462	64575462	64575462	-
NM_001370259.2(MEN1):c.554T>C (p.Val185Ala)	4221	MEN1	Uncertain significance	764847812	RCV000558442\|RCV001024261;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575463	64575463	11:g.64575463A>G	ClinGen:CA061289	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.553G>C (p.Val185Leu)	4221	MEN1	Uncertain significance	1265797059	RCV001321300;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575464	64575464	64575464	-
NM_001370259.2(MEN1):c.551T>A (p.Val184Glu)	4221	MEN1	Pathogenic	104894262	RCV000018177;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575466	64575466	11:g.64575466A>T	ClinGen:CA009488,UniProtKB:O00255#VAR_005445,OMIM:613733.0021	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.549G>C (p.Trp183Cys)	4221	MEN1	Pathogenic	2136153753	RCV002037784;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575468	64575468	64575468	-
NM_001370259.2(MEN1):c.549G>A (p.Trp183Ter)	4221	MEN1	Pathogenic	-1	RCV003062405;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575468	64575468	NC_000011.9:g.64575468C>T	-
NM_001370259.2(MEN1):c.548G>A (p.Trp183Ter)	4221	MEN1	Pathogenic	794728650	RCV000659844\|RCV003165391;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575469	64575469	NC_000011.9:g.64575469C>T	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.544G>C (p.Ala182Pro)	4221	MEN1	Uncertain significance	-1	RCV002715109;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575473	64575473	NC_000011.9:g.64575473C>G	-
NM_001370259.2(MEN1):c.542A>G (p.His181Arg)	4221	MEN1	Pathogenic/Likely pathogenic	1941861451	RCV001574143\|RCV001069023\|RCV002348477;	N	MedGen:C3661900\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575475	64575475	11:g.64575475T>C	-
NM_001370259.2(MEN1):c.539A>T (p.Asp180Val)	4221	MEN1	Uncertain significance	1064794683	RCV000487365\|RCV001049493;	N	MedGen:CN517202\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575478	64575478	11:g.64575478T>A	ClinGen:CA16619364	CN169374 not specified;
NM_001370259.2(MEN1):c.537_538delinsTT (p.Glu179_Asp180delinsAspTyr)	4221	MEN1	Uncertain significance	1555165809	RCV000545198;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575479	64575480	NC_000011.9:g.64575479_64575480delinsAA	ClinGen:CA658658067	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.538G>T (p.Asp180Tyr)	4221	MEN1	Uncertain significance	2136154322	RCV001367443;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575479	64575479	64575479	-
NM_001370259.2(MEN1):c.537G>C (p.Glu179Asp)	4221	MEN1	Conflicting interpretations of pathogenicity	1555165811	RCV000521106\|RCV001228587;	N	MedGen:CN517202\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575480	64575480	11:g.64575480C>G	ClinGen:CA381185889	CN169374 not specified;
NM_001370259.2(MEN1):c.534dup (p.Glu179Ter)	4221	MEN1	Pathogenic	2136154587	RCV001979712;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575482	64575483	64575482	-
NM_001370259.2(MEN1):c.531G>A (p.Leu177=)	4221	MEN1	Likely benign	146568011	RCV000226931\|RCV000254470\|RCV000491307;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:CN169374\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575486	64575486	NC_000011.9:g.64575486C>T	ClinGen:CA061284	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.530T>C (p.Leu177Pro)	4221	MEN1	Uncertain significance	2136154828	RCV001368589;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575487	64575487	64575487	-
NM_001370259.2(MEN1):c.529C>G (p.Leu177Val)	4221	MEN1	Uncertain significance	865919253	RCV000813107;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575488	64575488	11:g.64575488G>C	-
NM_001370259.2(MEN1):c.528C>A (p.Ala176=)	4221	MEN1	Likely benign	1311592330	RCV002194362;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575489	64575489	64575489	-
NM_001370259.2(MEN1):c.528C>G (p.Ala176=)	4221	MEN1	Likely benign	1311592330	RCV002144736\|RCV002346457;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575489	64575489	64575489	-
NM_001370259.2(MEN1):c.526G>C (p.Ala176Pro)	4221	MEN1	Pathogenic/Likely pathogenic	376872829	RCV000491572\|RCV000505771\|RCV000551917;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575491	64575491	NC_000011.9:g.64575491C>G	ClinGen:CA009468	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.526G>T (p.Ala176Ser)	4221	MEN1	Conflicting interpretations of pathogenicity	376872829	RCV000573513\|RCV000632090\|RCV002253513;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900	11	64575491	64575491	11:g.64575491C>A	ClinGen:CA061279	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.526G>A (p.Ala176Thr)	4221	MEN1	Uncertain significance	376872829	RCV001023830\|RCV001060544\|RCV003319433;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900	11	64575491	64575491	11:g.64575491C>T	-
NM_001370259.2(MEN1):c.525_526insTT (p.Ala176fs)	4221	MEN1	Pathogenic	1941864588	RCV001223479;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575491	64575492	11:g.64575491_64575492insAA	-
NM_001370259.2(MEN1):c.525C>T (p.Leu175=)	4221	MEN1	Likely benign	200155578	RCV000475141\|RCV000571355\|RCV003311820;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	11	64575492	64575492	NC_000011.9:g.64575492G>A	ClinGen:CA061272	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.516T>C (p.Asp172=)	4221	MEN1	Likely benign	912509147	RCV000573168\|RCV000894832;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575501	64575501	11:g.64575501A>G	ClinGen:CA223915742	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.514G>C (p.Asp172His)	4221	MEN1	Uncertain significance	1114167494	RCV001964122;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575503	64575503	64575503	-
NM_001370259.2(MEN1):c.513G>C (p.Arg171=)	4221	MEN1	Likely benign	560870111	RCV000204302\|RCV001023601;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575504	64575504	11:g.64575504C>G	ClinGen:CA061255	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.512G>A (p.Arg171Gln)	4221	MEN1	Conflicting interpretations of pathogenicity	607969	RCV000034787\|RCV000082337\|RCV000119143\|RCV000202713\|RCV000210794\|RCV001106456;	N	MedGen:C3661900\|MedGen:CN169374\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0017169,MedGen:C0027662,OMIM:PS131100, Orphanet:276161\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|Human Phenotype	11	64575505	64575505	11:g.64575505C>T	ClinGen:CA009454	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.512G>C (p.Arg171Pro)	4221	MEN1	Uncertain significance	607969	RCV001023592\|RCV001318116;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575505	64575505	11:g.64575505C>G	-
NM_001370259.2(MEN1):c.511C>T (p.Arg171Trp)	4221	MEN1	Conflicting interpretations of pathogenicity	143329068	RCV000148612\|RCV000410523\|RCV000455664\|RCV000569499\|RCV000766972\|RCV003153432;	N	Human Phenotype Ontology:HP:0000843,MONDO:MONDO:0001741,MedGen:C0020502\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:CN169374\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900\|MONDO:MOND	11	64575506	64575506	11:g.64575506G>A	ClinGen:CA009448	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.511C>G (p.Arg171Gly)	4221	MEN1	Uncertain significance	143329068	RCV002041674\|RCV003164019;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575506	64575506	64575506	-
NM_001370259.2(MEN1):c.509T>C (p.Leu170Pro)	4221	MEN1	Uncertain significance	1941866849	RCV001337463\|RCV003294322;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575508	64575508	64575508	-
NM_001370259.2(MEN1):c.506_507dup (p.Leu170fs)	4221	MEN1	Pathogenic	2136156268	RCV001384988;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575509	64575510	64575509	-
NM_001370259.2(MEN1):c.507T>G (p.Gly169=)	4221	MEN1	Likely benign	-1	RCV002834232;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575510	64575510		-
NM_001370259.2(MEN1):c.505G>A (p.Gly169Ser)	4221	MEN1	Uncertain significance	71526465	RCV001211689;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575512	64575512	11:g.64575512C>T	-
NM_001370259.2(MEN1):c.505G>C (p.Gly169Arg)	4221	MEN1	Uncertain significance	71526465	RCV001318355;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575512	64575512	64575512	-
NM_001370259.2(MEN1):c.504G>A (p.Leu168=)	4221	MEN1	Likely benign	1941867763	RCV001444252\|RCV003399233;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900	11	64575513	64575513	64575513	-
NM_001370259.2(MEN1):c.503T>C (p.Leu168Pro)	4221	MEN1	Pathogenic/Likely pathogenic	386134256	RCV000030205;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575514	64575514	11:g.64575514A>G	ClinGen:CA009447,UniProtKB:O00255#VAR_039598	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.502C>G (p.Leu168Val)	4221	MEN1	Uncertain significance	1555165846	RCV000632089;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575515	64575515	11:g.64575515G>C	ClinGen:CA381186060	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.502C>T (p.Leu168=)	4221	MEN1	Likely benign	1555165846	RCV001479658\|RCV003380795;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575515	64575515	11:g.64575515G>A	-
NM_001370259.2(MEN1):c.499G>A (p.Ala167Thr)	4221	MEN1	Uncertain significance	-1	RCV003043807;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575518	64575518	NC_000011.9:g.64575518C>T	-
NM_001370259.2(MEN1):c.498G>C (p.Gln166His)	4221	MEN1	Uncertain significance	-1	RCV003110752;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575519	64575519	NC_000011.9:g.64575519C>G	-
NM_001370259.2(MEN1):c.497A>C (p.Gln166Pro)	4221	MEN1	Uncertain significance	-1	RCV003058092;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575520	64575520	NC_000011.9:g.64575520T>G	-
NM_001370259.2(MEN1):c.496C>A (p.Gln166Lys)	4221	MEN1	Uncertain significance	1565648511	RCV002028282;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575521	64575521	64575521	-
NM_001370259.2(MEN1):c.496C>G (p.Gln166Glu)	4221	MEN1	Uncertain significance	1565648511	RCV002008712;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575521	64575521	64575521	-
NM_001370259.2(MEN1):c.495C>A (p.Cys165Ter)	4221	MEN1	Pathogenic	1592651767	RCV000793204;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575522	64575522	11:g.64575522G>T	-
NM_001370259.2(MEN1):c.494G>A (p.Cys165Tyr)	4221	MEN1	Likely pathogenic	1057521111	RCV000442726\|RCV000632126;	N	MedGen:CN517202\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575523	64575523	11:g.64575523C>T	ClinGen:CA16605984	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.492C>T (p.Ala164=)	4221	MEN1	Benign/Likely benign	146759807	RCV000030204\|RCV000610718\|RCV001023275;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:CN169374\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575525	64575525	11:g.64575525G>A	ClinGen:CA009441	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.491C>T (p.Ala164Val)	4221	MEN1	Likely pathogenic	1565648547	RCV000702798;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575526	64575526	NC_000011.9:g.64575526G>A	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.491C>A (p.Ala164Asp)	4221	MEN1	Likely pathogenic	1565648547	RCV001220086;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575526	64575526	11:g.64575526G>T	-
NM_001370259.2(MEN1):c.490G>T (p.Ala164Ser)	4221	MEN1	Uncertain significance	1311408888	RCV000807278;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575527	64575527	11:g.64575527C>A	-
NM_001370259.2(MEN1):c.489G>A (p.Gly163=)	4221	MEN1	Likely benign	2136157212	RCV002150012;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575528	64575528	64575528	-
NM_001370259.2(MEN1):c.485T>C (p.Val162Ala)	4221	MEN1	Uncertain significance	748648909	RCV000632131\|RCV002334065;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575532	64575532	NC_000011.9:g.64575532A>G	ClinGen:CA061208	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.484G>A (p.Val162Ile)	4221	MEN1	Uncertain significance	2136157511	RCV001913494;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575533	64575533	64575533	-
NM_001370259.2(MEN1):c.483G>A (p.Val161=)	4221	MEN1	Likely benign	-1	RCV002876382;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575534	64575534		-
NM_001370259.2(MEN1):c.481G>A (p.Val161Met)	4221	MEN1	Uncertain significance	1268563474	RCV001370887\|RCV002341802;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575536	64575536	64575536	-
NM_001370259.2(MEN1):c.480T>C (p.Ala160=)	4221	MEN1	Likely benign	2136157794	RCV001486862\|RCV002342098;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575537	64575537	64575537	-
NM_001370259.2(MEN1):c.478G>C (p.Ala160Pro)	4221	MEN1	Pathogenic	1565648656	RCV000702232\|RCV001269817\|RCV002334355;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575539	64575539	NC_000011.9:g.64575539C>G	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.477T>G (p.Phe159Leu)	4221	MEN1	Uncertain significance	1941871397	RCV001343081\|RCV002341705;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575540	64575540	64575540	-
NM_001370259.2(MEN1):c.474C>T (p.Ala158=)	4221	MEN1	Likely benign	772526802	RCV000632164\|RCV002331118;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575543	64575543	NC_000011.9:g.64575543G>A	ClinGen:CA061203	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.474del (p.Phe159fs)	4221	MEN1	Pathogenic	2136158237	RCV001385039;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575543	64575543	64575542	-
NM_001370259.2(MEN1):c.473C>A (p.Ala158Asp)	4221	MEN1	Conflicting interpretations of pathogenicity	794728617	RCV000474814\|RCV003380506;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575544	64575544	NC_000011.9:g.64575544G>T	ClinGen:CA009435	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.473C>T (p.Ala158Val)	4221	MEN1	Uncertain significance	794728617	RCV000697548\|RCV002334332;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575544	64575544	NC_000011.9:g.64575544G>A	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.472G>A (p.Ala158Thr)	4221	MEN1	Uncertain significance	1421808873	RCV001361174\|RCV003298569;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575545	64575545	64575545	-
NM_001370259.2(MEN1):c.471G>A (p.Val157=)	4221	MEN1	Likely benign	878855194	RCV000233035\|RCV000572540;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575546	64575546	NC_000011.9:g.64575546C>T	ClinGen:CA10582942	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.469G>A (p.Val157Met)	4221	MEN1	Uncertain significance	1555165872	RCV000632108;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575548	64575548	NC_000011.9:g.64575548C>T	ClinGen:CA381186239	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.467G>A (p.Gly156Asp)	4221	MEN1	Pathogenic/Likely pathogenic	794728648	RCV000425558\|RCV000466874\|RCV000491482;	N	MedGen:C3661900\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575550	64575550	11:g.64575550C>T	ClinGen:CA16605985	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.465_466insAATT (p.Gly156fs)	4221	MEN1	Likely pathogenic	386134255	RCV000030203;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575551	64575552	11:g.64575551_64575552insAATT	ClinGen:CA009428	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.466G>C (p.Gly156Arg)	4221	MEN1	Pathogenic/Likely pathogenic	1085307471	RCV000489416\|RCV003155212;	N	MedGen:CN517202\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575551	64575551	11:g.64575551C>G	ClinGen:CA381186242	CN517202 not provided;
NM_001370259.2(MEN1):c.466G>A (p.Gly156Ser)	4221	MEN1	Conflicting interpretations of pathogenicity	1085307471	RCV000702784\|RCV001269816\|RCV002332492;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575551	64575551	NC_000011.9:g.64575551C>T	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.466G>T (p.Gly156Cys)	4221	MEN1	Pathogenic/Likely pathogenic	1085307471	RCV001269563\|RCV001880194\|RCV002327616;	N	MedGen:C3661900\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575551	64575551	11:g.64575551C>A	-
NM_001370259.2(MEN1):c.465C>T (p.Ser155=)	4221	MEN1	Likely benign	936786553	RCV000539439\|RCV001022861;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64575552	64575552	11:g.64575552G>A	ClinGen:CA223915904	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.464C>T (p.Ser155Phe)	4221	MEN1	Uncertain significance	-1	RCV003062406;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575553	64575553	NC_000011.9:g.64575553G>A	-
NM_001370259.2(MEN1):c.461G>T (p.Ser154Ile)	4221	MEN1	Uncertain significance	1941873896	RCV001320603;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575556	64575556	64575556	-
NM_001370259.2(MEN1):c.459C>T (p.Asp153=)	4221	MEN1	Likely benign	-1	RCV002815574;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575558	64575558		-
NM_001370259.2(MEN1):c.458A>T (p.Asp153Val)	4221	MEN1	Pathogenic	1565648789	RCV000703817;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575559	64575559	NC_000011.9:g.64575559T>A	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.458A>C (p.Asp153Ala)	4221	MEN1	Likely pathogenic	1565648789	RCV001973475;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575559	64575559	64575559	-
NM_001370259.2(MEN1):c.452A>G (p.Lys151Arg)	4221	MEN1	Uncertain significance	2136159495	RCV001364235;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575565	64575565	64575565	-
NM_001370259.2(MEN1):c.451A>G (p.Lys151Glu)	4221	MEN1	Uncertain significance	2136159555	RCV002005494;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575566	64575566	64575566	-
NM_001370259.2(MEN1):c.447C>T (p.Gly149=)	4221	MEN1	Likely benign	-1	RCV002863723;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575570	64575570		-
NM_001370259.2(MEN1):c.446G>T (p.Gly149Val)	4221	MEN1	Uncertain significance	1444210255	RCV001365861;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575571	64575571	64575571	-
NM_001370259.2(MEN1):c.446-1G>A	4221	MEN1	Pathogenic	1064793672	RCV000487061\|RCV001022519\|RCV001851155;	N	MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575572	64575572	11:g.64575572C>T	ClinGen:CA16619366	CN517202 not provided;
NM_001370259.2(MEN1):c.446-1G>C	4221	MEN1	Pathogenic	1064793672	RCV000820156;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575572	64575572	11:g.64575572C>G	-
NM_001370259.2(MEN1):c.446-2A>C	4221	MEN1	Pathogenic	886042035	RCV000406326\|RCV003233029;	N	MedGen:CN517202\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575573	64575573	11:g.64575573T>G	ClinGen:CA10603221	CN517202 not provided;
NM_001370259.2(MEN1):c.446-2A>G	4221	MEN1	Pathogenic	886042035	RCV000491191\|RCV000696685\|RCV002475967;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900	11	64575573	64575573	NC_000011.9:g.64575573T>C	ClinGen:CA381186358	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.446-3C>A	4221	MEN1	Uncertain significance	377461506	RCV000490866\|RCV000531853;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575574	64575574	11:g.64575574G>T	ClinGen:CA061191	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.446-3C>T	4221	MEN1	Uncertain significance	377461506	RCV001338619;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575574	64575574	64575574	-
NM_001370259.2(MEN1):c.446-6C>A	4221	MEN1	Uncertain significance	1941875791	RCV001054998;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575577	64575577	11:g.64575577G>T	-
NM_001370259.2(MEN1):c.446-7T>C	4221	MEN1	Likely benign	2136160148	RCV002158677;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575578	64575578	64575578	-
NM_001370259.2(MEN1):c.446-9C>A	4221	MEN1	Likely benign	1371109251	RCV000632170;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575580	64575580	NC_000011.9:g.64575580G>T	ClinGen:CA658797661	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.446-9C>G	4221	MEN1	Likely benign	1371109251	RCV001466562;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575580	64575580	64575580	-
NM_001370259.2(MEN1):c.446-10C>T	4221	MEN1	Likely benign	1442401628	RCV001426994;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575581	64575581	11:g.64575581G>A	-
NM_001370259.2(MEN1):c.446-10C>A	4221	MEN1	Likely benign	1442401628	RCV002134478;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575581	64575581	64575581	-
NM_001370259.2(MEN1):c.446-11C>G	4221	MEN1	Likely benign	1273035105	RCV002112622;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575582	64575582	64575582	-
NM_001370259.2(MEN1):c.446-12C>T	4221	MEN1	Likely benign	369411199	RCV002081844;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575583	64575583	64575583	-
NM_001370259.2(MEN1):c.446-17A>G	4221	MEN1	Likely benign	-1	RCV003030151;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575588	64575588	NC_000011.9:g.64575588T>C	-
NM_001370259.2(MEN1):c.446-18T>C	4221	MEN1	Likely benign	2136160575	RCV002099695;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64575589	64575589	64575589	-
NC_000011.10:g.(?_64809655)_(64810716_?)del	4221	MEN1	Pathogenic	-1	RCV001033796;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577127	64578188	-1	-
NC_000011.10:g.(?_64809655)_(64810716_?)dup	4221	MEN1	Uncertain significance	-1	RCV001032045;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577127	64578188	-1	-
NM_001370259.2(MEN1):c.445+10C>T	4221	MEN1	Likely benign	754044830	RCV001411450;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577127	64577127	64577127	-
NM_001370259.2(MEN1):c.445+9C>G	4221	MEN1	Likely benign	2136177395	RCV002175861;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577128	64577128	64577128	-
NM_001370259.2(MEN1):c.445+7G>T	4221	MEN1	Likely benign	2136177428	RCV001487264;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577130	64577130	64577130	-
NC_000011.10:g.(?_64809659)_(64810115_?)del	4221	MEN1	Pathogenic	-1	RCV000632178;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577131	64577587		-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.445+5G>A	4221	MEN1	Uncertain significance	1941974766	RCV001233955;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577132	64577132	11:g.64577132C>T	-
NM_001370259.2(MEN1):c.445+4G>A	4221	MEN1	Uncertain significance	1941974933	RCV001043217;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577133	64577133	11:g.64577133C>T	-
NM_001370259.2(MEN1):c.445+3T>C	4221	MEN1	Uncertain significance	2136177528	RCV001980993;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577134	64577134	64577134	-
NM_001370259.2(MEN1):c.445+1G>T	4221	MEN1	Likely pathogenic	-1	RCV002806707;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577136	64577136	NC_000011.9:g.64577136C>A	-
NM_001370259.2(MEN1):c.443C>T (p.Thr148Ile)	4221	MEN1	Uncertain significance	-1	RCV003288354\|RCV003459820;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577139	64577139		-
NM_001370259.2(MEN1):c.442A>G (p.Thr148Ala)	4221	MEN1	Uncertain significance	1114167537	RCV000492024\|RCV001856929;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577140	64577140	NC_000011.9:g.64577140T>C	ClinGen:CA381186661	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.442del (p.Thr148fs)	4221	MEN1	Pathogenic	1941975256	RCV001240328\|RCV002327581;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577140	64577140	11:g.64577140_64577140del	-
NM_001370259.2(MEN1):c.441C>T (p.Ile147=)	4221	MEN1	Likely benign	878855193	RCV000230248\|RCV002327146;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577141	64577141	11:g.64577141G>A	ClinGen:CA10582943	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.435C>T (p.Ser145=)	4221	MEN1	Benign	61736636	RCV000082336\|RCV000378351\|RCV000491558\|RCV000712292\|RCV000999732;	N	MedGen:CN169374\|Human Phenotype Ontology:HP:0000843,MONDO:MONDO:0001741,MedGen:C0020502\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577147	64577147	11:g.64577147G>A	ClinGen:CA009422	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.434G>C (p.Ser145Thr)	4221	MEN1	Uncertain significance	-1	RCV002833155;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577148	64577148	NC_000011.9:g.64577148C>G	-
NM_001370259.2(MEN1):c.432C>A (p.Phe144Leu)	4221	MEN1	Uncertain significance	2136177828	RCV002032936;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577150	64577150	64577150	-
NM_001370259.2(MEN1):c.432C>G (p.Phe144Leu)	4221	MEN1	Uncertain significance	-1	RCV003470097;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577150	64577150		-
NM_001370259.2(MEN1):c.430T>G (p.Phe144Val)	4221	MEN1	Conflicting interpretations of pathogenicity	1114167543	RCV000491902\|RCV001000177;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577152	64577152	11:g.64577152A>C	ClinGen:CA381186717	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.428T>C (p.Leu143Pro)	4221	MEN1	Uncertain significance	2136178143	RCV001969885;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577154	64577154	64577154	-
NM_001370259.2(MEN1):c.428T>G (p.Leu143Arg)	4221	MEN1	Likely pathogenic	-1	RCV003233051;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577154	64577154		-
NM_001370259.2(MEN1):c.427C>G (p.Leu143Val)	4221	MEN1	Uncertain significance	-1	RCV003121392;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577155	64577155	NC_000011.9:g.64577155G>C	-
NM_001370259.2(MEN1):c.426C>T (p.Ser142=)	4221	MEN1	Likely benign	753252650	RCV000458015\|RCV002329087;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577156	64577156	NC_000011.9:g.64577156G>A	ClinGen:CA061134	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.425C>T (p.Ser142Phe)	4221	MEN1	Uncertain significance	1941976986	RCV001322404;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577157	64577157	64577157	-
NM_001370259.2(MEN1):c.425C>A (p.Ser142Tyr)	4221	MEN1	Uncertain significance	1941976986	RCV001338745\|RCV002329309;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577157	64577157	64577157	-
NM_001370259.2(MEN1):c.425C>G (p.Ser142Cys)	4221	MEN1	Uncertain significance	1941976986	RCV001373824;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577157	64577157	64577157	-
NM_001370259.2(MEN1):c.422A>G (p.Gln141Arg)	4221	MEN1	Uncertain significance	758846538	RCV001323222;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577160	64577160	64577160	-
NM_001370259.2(MEN1):c.421C>T (p.Gln141Ter)	4221	MEN1	Pathogenic	886039553	RCV000255977\|RCV000632106;	N	MedGen:CN517202\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577161	64577161	11:g.64577161G>A	ClinGen:CA10588534	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.420C>T (p.Ile140=)	4221	MEN1	Likely benign	-1	RCV003086842;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577162	64577162		-
NM_001370259.2(MEN1):c.418A>T (p.Ile140Phe)	4221	MEN1	Uncertain significance	376510601	RCV000632107\|RCV002331117;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577164	64577164	11:g.64577164T>A	ClinGen:CA381186778	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.418A>G (p.Ile140Val)	4221	MEN1	Uncertain significance	-1	RCV002834956;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577164	64577164	NC_000011.9:g.64577164T>C	-
NM_001370259.2(MEN1):c.417C>G (p.His139Gln)	4221	MEN1	Likely pathogenic	386134254	RCV000030202;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577165	64577165	11:g.64577165G>C	ClinGen:CA009417	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.417C>T (p.His139=)	4221	MEN1	Likely benign	-1	RCV003069294;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577165	64577165		-
NM_001370259.2(MEN1):c.416A>C (p.His139Pro)	4221	MEN1	Likely pathogenic	-1	RCV003062407;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577166	64577166	NC_000011.9:g.64577166T>G	-
NM_001370259.2(MEN1):c.416del (p.His139fs)	4221	MEN1	Pathogenic	-1	RCV002828881;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577166	64577166	NC_000011.9:g.64577166del	-
NM_001370259.2(MEN1):c.415C>G (p.His139Asp)	4221	MEN1	Pathogenic	104894263	RCV000018179\|RCV000491226;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577167	64577167	11:g.64577167G>C	ClinGen:CA009410,UniProtKB:O00255#VAR_005432,OMIM:613733.0023	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.406_415delinsTCCCT (p.Asp136fs)	4221	MEN1	Pathogenic	1592657785	RCV000822487;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577167	64577176	11:g.64577168_64577176del	-
NM_001370259.2(MEN1):c.415C>T (p.His139Tyr)	4221	MEN1	Pathogenic	104894263	RCV001224950;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577167	64577167	11:g.64577167G>A	-
NM_001370259.2(MEN1):c.411G>C (p.Arg137=)	4221	MEN1	Likely benign	371437505	RCV001414060\|RCV002320115;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577171	64577171	11:g.64577171C>G	-
NM_001370259.2(MEN1):c.411G>T (p.Arg137=)	4221	MEN1	Likely benign	371437505	RCV001410663;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577171	64577171	64577171	-
NM_001370259.2(MEN1):c.409C>T (p.Arg137Trp)	4221	MEN1	Uncertain significance	1208267598	RCV000709160;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577173	64577173	11:g.64577173G>A	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.409C>A (p.Arg137=)	4221	MEN1	Likely benign	1208267598	RCV001216091\|RCV002322049;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577173	64577173	11:g.64577173G>T	-
NM_001370259.2(MEN1):c.392_407dup (p.Asp136fs)	4221	MEN1	Pathogenic	-1	RCV003013777;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577174	64577175	NC_000011.9:g.64577175_64577190dup	-
NM_001370259.2(MEN1):c.406G>C (p.Asp136His)	4221	MEN1	Uncertain significance	1941979334	RCV001327184\|RCV003405552;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|	11	64577176	64577176	64577176	-
NM_001370259.2(MEN1):c.403A>C (p.Lys135Gln)	4221	MEN1	Uncertain significance	121913034	RCV000226206;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577179	64577179	NC_000011.9:g.64577179T>G	ClinGen:CA10582944	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.402del (p.Phe134fs)	4221	MEN1	Pathogenic	397515385	RCV000018161\|RCV000182436\|RCV000491332;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577180	64577180	11:g.64577180_64577180del	ClinGen:CA009401,OMIM:613733.0005	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.399C>T (p.Tyr133=)	4221	MEN1	Likely benign	1592657892	RCV001021611\|RCV001442297;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577183	64577183	11:g.64577183G>A	-
NM_001370259.2(MEN1):c.398A>G (p.Tyr133Cys)	4221	MEN1	Uncertain significance	1555166357	RCV000555824;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577184	64577184	11:g.64577184T>C	ClinGen:CA381187243	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.396C>T (p.Ser132=)	4221	MEN1	Likely benign	896947172	RCV001021551\|RCV001465314;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577186	64577186	11:g.64577186G>A	-
NM_001370259.2(MEN1):c.391C>T (p.Arg131Cys)	4221	MEN1	Uncertain significance	2136180282	RCV001947792;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577191	64577191	64577191	-
NM_001370259.2(MEN1):c.390C>T (p.Ser130=)	4221	MEN1	Likely benign	771272168	RCV001021418\|RCV001462657;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577192	64577192	11:g.64577192G>A	-
NM_001370259.2(MEN1):c.388A>T (p.Ser130Cys)	4221	MEN1	Uncertain significance	2136180487	RCV002018830;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577194	64577194	64577194	-
NM_001370259.2(MEN1):c.387C>G (p.Leu129=)	4221	MEN1	Likely benign	1257890690	RCV002079288\|RCV002363637;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577195	64577195	64577195	-
NM_001370259.2(MEN1):c.386del (p.Leu129fs)	4221	MEN1	Pathogenic	1565651223	RCV000707308\|RCV002352222;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577196	64577196	NC_000011.9:g.64577196del	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.381C>G (p.Asn127Lys)	4221	MEN1	Uncertain significance	1941981145	RCV001320746;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577201	64577201	64577201	-
NM_001370259.2(MEN1):c.380A>G (p.Asn127Ser)	4221	MEN1	Uncertain significance	2136180841	RCV001947719;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577202	64577202	64577202	-
NM_001370259.2(MEN1):c.378G>A (p.Trp126Ter)	4221	MEN1	Pathogenic	1555166365	RCV000632079;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577204	64577204	NC_000011.9:g.64577204C>T	ClinGen:CA381187290	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.377G>A (p.Trp126Ter)	4221	MEN1	Pathogenic	2136181049	RCV001916061;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577205	64577205	64577205	-
NM_001370259.2(MEN1):c.375A>T (p.Ile125=)	4221	MEN1	Likely benign	184896922	RCV000464805\|RCV001021065;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577207	64577207	NC_000011.9:g.64577207T>A	ClinGen:CA061103	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.375A>C (p.Ile125=)	4221	MEN1	Likely benign	184896922	RCV000632172;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577207	64577207	NC_000011.9:g.64577207T>G	ClinGen:CA475163329	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.374T>C (p.Ile125Thr)	4221	MEN1	Uncertain significance	1941982084	RCV001371842;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577208	64577208	64577208	-
NM_001370259.2(MEN1):c.373A>T (p.Ile125Leu)	4221	MEN1	Uncertain significance	1941982271	RCV001913444;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577209	64577209	64577209	-
NM_001370259.2(MEN1):c.371_372del (p.Val124fs)	4221	MEN1	Pathogenic	1555166368	RCV000626631\|RCV001198162;	N	6 conditions\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577210	64577211	NC_000011.9:g.64577210_64577211del	ClinGen:CA658797663	C4025337 Abnormality of calcium homeostasis;
NM_001370259.2(MEN1):c.369T>C (p.Asp123=)	4221	MEN1	Likely benign	1555166369	RCV000632171;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577213	64577213	NC_000011.9:g.64577213A>G	ClinGen:CA475163341	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.367del (p.Asp123fs)	4221	MEN1	Pathogenic	1941982919	RCV001215633;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577215	64577215	11:g.64577215_64577215del	-
NM_001370259.2(MEN1):c.367G>A (p.Asp123Asn)	4221	MEN1	Uncertain significance	1941982745	RCV002014072;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577215	64577215	64577215	-
NM_001370259.2(MEN1):c.366C>T (p.Ser122=)	4221	MEN1	Likely benign	1592658043	RCV000817967\|RCV002453865;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577216	64577216	11:g.64577216G>A	-
NM_001370259.2(MEN1):c.364T>C (p.Ser122Pro)	4221	MEN1	Uncertain significance	1941983276	RCV001070452;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577218	64577218	11:g.64577218A>G	-
NM_001370259.2(MEN1):c.361G>A (p.Val121Ile)	4221	MEN1	Uncertain significance	863224812	RCV000199154\|RCV002460056;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577221	64577221	NC_000011.9:g.64577221C>T	ClinGen:CA338424	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.361G>T (p.Val121Phe)	4221	MEN1	Uncertain significance	863224812	RCV000706162\|RCV002458317;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577221	64577221	NC_000011.9:g.64577221C>A	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.355AAG[1] (p.Lys120del)	4221	MEN1	Pathogenic	794728657	RCV000018160\|RCV000182460\|RCV000491280;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577222	64577224	NC_000011.9:g.64577223TTC[1]	ClinGen:CA009382,OMIM:613733.0004,OMIM:613733.0025	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.360G>A (p.Lys120=)	4221	MEN1	Likely benign	1477714779	RCV001464659;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577222	64577222	64577222	-
NM_001370259.2(MEN1):c.358A>T (p.Lys120Ter)	4221	MEN1	Pathogenic	878855192	RCV000232425;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577224	64577224	NC_000011.9:g.64577224T>A	ClinGen:CA10582945	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.352G>A (p.Val118Met)	4221	MEN1	Uncertain significance	1060499975	RCV000472854\|RCV002339107;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577230	64577230	NC_000011.9:g.64577230C>T	ClinGen:CA16613633	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.350del (p.Leu117fs)	4221	MEN1	Pathogenic	1555166387	RCV000508545\|RCV001380012\|RCV002455979;	N	MedGen:CN169374\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577232	64577232	NC_000011.9:g.64577232del	ClinGen:CA645509451	CN169374 not specified;
NM_001370259.2(MEN1):c.350T>A (p.Leu117Gln)	4221	MEN1	Uncertain significance	-1	RCV002300108\|RCV003382883;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577232	64577232	64577232	-
NM_001370259.2(MEN1):c.346G>T (p.Glu116Ter)	4221	MEN1	Pathogenic	1060499992	RCV000469372\|RCV002451060;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577236	64577236	NC_000011.9:g.64577236C>A	ClinGen:CA16613475	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.346G>A (p.Glu116Lys)	4221	MEN1	Uncertain significance	1060499992	RCV001296254;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577236	64577236	64577236	-
NM_001370259.2(MEN1):c.345T>C (p.Arg115=)	4221	MEN1	Likely benign	748948131	RCV000632174\|RCV002458003;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577237	64577237	NC_000011.9:g.64577237A>G	ClinGen:CA061085	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.344G>A (p.Arg115His)	4221	MEN1	Uncertain significance	1114167507	RCV000491521\|RCV000526098\|RCV001755730;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900	11	64577238	64577238	NC_000011.9:g.64577238C>T	ClinGen:CA381187365	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.343C>G (p.Arg115Gly)	4221	MEN1	Uncertain significance	1565651402	RCV000709161\|RCV001020310;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577239	64577239	11:g.64577239G>C	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.343del (p.Arg115fs)	4221	MEN1	Pathogenic	-1	RCV002457107\|RCV003099486;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577239	64577239	64577238	-
NM_001370259.2(MEN1):c.342C>T (p.Ser114=)	4221	MEN1	Likely benign	2136182809	RCV002176239\|RCV002454562;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577240	64577240	64577240	-
NM_001370259.2(MEN1):c.340dup (p.Ser114fs)	4221	MEN1	Pathogenic	886041213	RCV000309108\|RCV000490981\|RCV001046917;	N	MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577241	64577242	11:g.64577241_64577242insT	ClinGen:CA10603131	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.340A>C (p.Ser114Arg)	4221	MEN1	Uncertain significance	2136182944	RCV001896383;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577242	64577242	64577242	-
NM_001370259.2(MEN1):c.339C>T (p.Ser113=)	4221	MEN1	Benign/Likely benign	559635859	RCV000197663\|RCV000570477;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577243	64577243	11:g.64577243G>A	ClinGen:CA061082	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.338C>T (p.Ser113Phe)	4221	MEN1	Uncertain significance	1941986326	RCV001305573;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577244	64577244	64577244	-
NM_001370259.2(MEN1):c.336C>G (p.Val112=)	4221	MEN1	Likely benign	1200092213	RCV000925056\|RCV001020110;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577246	64577246	11:g.64577246G>C	-
NM_001370259.2(MEN1):c.336C>T (p.Val112=)	4221	MEN1	Likely benign	1200092213	RCV002170731\|RCV002454356;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577246	64577246	64577246	-
NM_001370259.2(MEN1):c.333T>C (p.Gly111=)	4221	MEN1	Likely benign	1555166432	RCV000632173;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577249	64577249	11:g.64577249A>G	ClinGen:CA475163444	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.332G>T (p.Gly111Val)	4221	MEN1	Uncertain significance	2136183365	RCV001957053;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577250	64577250	64577250	-
NM_001370259.2(MEN1):c.332del (p.Gly111fs)	4221	MEN1	Pathogenic	-1	RCV003084889;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577250	64577250	NC_000011.9:g.64577254del	-
NM_001370259.2(MEN1):c.332G>A (p.Gly111Asp)	4221	MEN1	Uncertain significance	-1	RCV002599321;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577250	64577250	NC_000011.9:g.64577250C>T	-
NM_001370259.2(MEN1):c.331G>C (p.Gly111Arg)	4221	MEN1	Uncertain significance	1941987221	RCV001043888;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577251	64577251	11:g.64577251C>G	-
NM_001370259.2(MEN1):c.330G>C (p.Gly110=)	4221	MEN1	Likely benign	1060503792	RCV001500044;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577252	64577252	NC_000011.9:g.64577252C>G	ClinGen:CA16613477	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.329G>C (p.Gly110Ala)	4221	MEN1	Uncertain significance	1389398299	RCV000708706\|RCV001036768;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577253	64577253	11:g.64577253C>G	-	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.329G>A (p.Gly110Glu)	4221	MEN1	Conflicting interpretations of pathogenicity	1389398299	RCV001049265\|RCV002320278;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577253	64577253	11:g.64577253C>T	-
NM_001370259.2(MEN1):c.327A>C (p.Glu109Asp)	4221	MEN1	Uncertain significance	773976527	RCV000338822\|RCV000686479\|RCV003343768;	N	Human Phenotype Ontology:HP:0000843,MONDO:MONDO:0001741,MedGen:C0020502\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577255	64577255	11:g.64577255T>G	ClinGen:CA061079	C0020502 Hyperparathyroidism;
NM_001370259.2(MEN1):c.326A>G (p.Glu109Gly)	4221	MEN1	Uncertain significance	1555166447	RCV000571825\|RCV000632088;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577256	64577256	11:g.64577256T>C	ClinGen:CA381187402	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.323del (p.Arg108fs)	4221	MEN1	Pathogenic	878855191	RCV000229514;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577259	64577259	11:g.64577259_64577259del	ClinGen:CA10582946	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.322_323insT (p.Arg108fs)	4221	MEN1	Pathogenic	1565651568	RCV000687229;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577259	64577260	11:g.64577259_64577260insA	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.323G>A (p.Arg108Gln)	4221	MEN1	Uncertain significance	1565651551	RCV001214460;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577259	64577259	11:g.64577259C>T	-
NM_001370259.2(MEN1):c.322C>T (p.Arg108Ter)	4221	MEN1	Pathogenic	794728647	RCV000182446\|RCV000491814\|RCV000551465;	N	MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577260	64577260	NC_000011.9:g.64577260G>A	ClinGen:CA009370	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.322C>G (p.Arg108Gly)	4221	MEN1	Uncertain significance	794728647	RCV000686088;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577260	64577260	11:g.64577260G>C	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.321T>C (p.Pro107=)	4221	MEN1	Likely benign	2136184097	RCV001396015;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577261	64577261	64577261	-
NM_001370259.2(MEN1):c.320dup (p.Arg108fs)	4221	MEN1	Pathogenic/Likely pathogenic	-1	RCV003062408;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577261	64577262	NC_000011.9:g.64577263dup	-
NM_001370259.2(MEN1):c.319C>T (p.Pro107Ser)	4221	MEN1	Uncertain significance	1358503577	RCV001215364;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577263	64577263	11:g.64577263G>A	-
NM_001370259.2(MEN1):c.319C>G (p.Pro107Ala)	4221	MEN1	Uncertain significance	-1	RCV003461847;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577263	64577263		-
NM_001370259.2(MEN1):c.318T>A (p.Tyr106Ter)	4221	MEN1	Pathogenic	1060499987	RCV000472445;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577264	64577264	NC_000011.9:g.64577264A>T	ClinGen:CA16613689	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.317_318del (p.Tyr106fs)	4221	MEN1	Pathogenic	1555166466	RCV000539020;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577264	64577265	11:g.64577264_64577265del	ClinGen:CA658658068	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.317A>G (p.Tyr106Cys)	4221	MEN1	Uncertain significance	1555166469	RCV000571119\|RCV000804799;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577265	64577265	NC_000011.9:g.64577265T>C	ClinGen:CA381187419	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.312_315dup (p.Tyr106fs)	4221	MEN1	Pathogenic	1592658517	RCV000988574;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577266	64577267	11:g.64577266_64577267insGAGG	-
NM_001370259.2(MEN1):c.315C>G (p.Leu105=)	4221	MEN1	Likely benign	1238374960	RCV001018866\|RCV001504047;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577267	64577267	11:g.64577267G>C	-
NM_001370259.2(MEN1):c.313dup (p.Leu105fs)	4221	MEN1	Pathogenic	2136184555	RCV001956107;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577268	64577269	64577268	-
NM_001370259.2(MEN1):c.313C>G (p.Leu105Val)	4221	MEN1	Uncertain significance	1941990096	RCV001067526;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577269	64577269	11:g.64577269G>C	-
NM_001370259.2(MEN1):c.313C>T (p.Leu105Phe)	4221	MEN1	Uncertain significance	1941990096	RCV001979663;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577269	64577269	64577269	-
NM_001370259.2(MEN1):c.312C>T (p.Ser104=)	4221	MEN1	Likely benign	1592658525	RCV000933874;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577270	64577270	11:g.64577270G>A	-
NM_001370259.2(MEN1):c.311C>T (p.Ser104Phe)	4221	MEN1	Uncertain significance	1114167512	RCV001931951;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577271	64577271	64577271	-
NM_001370259.2(MEN1):c.308T>G (p.Leu103Arg)	4221	MEN1	Uncertain significance	2136184835	RCV001898307;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577274	64577274	64577274	-
NM_001370259.2(MEN1):c.307del (p.Leu103fs)	4221	MEN1	Pathogenic	794728639	RCV000018159\|RCV000182435\|RCV000491671;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577275	64577275	NC_000011.9:g.64577276del	ClinGen:CA009358,OMIM:613733.0003	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.307C>T (p.Leu103=)	4221	MEN1	Likely benign	1313314117	RCV000632147\|RCV002319543;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577275	64577275	11:g.64577275G>A	ClinGen:CA475163532	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.306C>T (p.Asp102=)	4221	MEN1	Likely benign	-1	RCV002647073\|RCV003308210;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577276	64577276		-
NM_001370259.2(MEN1):c.303C>T (p.Val101=)	4221	MEN1	Likely benign	1463347315	RCV000550285\|RCV002448631;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577279	64577279	NC_000011.9:g.64577279G>A	ClinGen:CA475163545	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.303C>G (p.Val101=)	4221	MEN1	Likely benign	1463347315	RCV002077438;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577279	64577279	64577279	-
NM_001370259.2(MEN1):c.302T>C (p.Val101Ala)	4221	MEN1	Uncertain significance	771936005	RCV001367153;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577280	64577280	64577280	-
NM_001370259.2(MEN1):c.301G>A (p.Val101Ile)	4221	MEN1	Uncertain significance	1242887389	RCV001018071\|RCV001873307;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577281	64577281	11:g.64577281C>T	-
NM_001370259.2(MEN1):c.300C>G (p.Ala100=)	4221	MEN1	Likely benign	773136972	RCV000679257\|RCV000613769\|RCV001087349\|RCV002438305;	N	MedGen:C3661900\|MedGen:CN169374\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577282	64577282	NC_000011.9:g.64577282G>C	ClinGen:CA061062	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.300C>T (p.Ala100=)	4221	MEN1	Likely benign	773136972	RCV001447332;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577282	64577282	64577282	-
NM_001370259.2(MEN1):c.299C>T (p.Ala100Val)	4221	MEN1	Conflicting interpretations of pathogenicity	998337367	RCV000632142\|RCV000679256\|RCV001017890;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577283	64577283	11:g.64577283G>A	ClinGen:CA223917061	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.298G>T (p.Ala100Ser)	4221	MEN1	Uncertain significance	1592658683	RCV000810478;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577284	64577284	11:g.64577284C>A	-
NM_001370259.2(MEN1):c.296G>C (p.Gly99Ala)	4221	MEN1	Uncertain significance	1941992512	RCV001238639;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577286	64577286	11:g.64577286C>G	-
NM_001370259.2(MEN1):c.294A>T (p.Arg98=)	4221	MEN1	Likely benign	2136185660	RCV001405558;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577288	64577288	64577288	-
NM_001370259.2(MEN1):c.293G>A (p.Arg98Gln)	4221	MEN1	Uncertain significance	1592658694	RCV000808557;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577289	64577289	11:g.64577289C>T	-
NM_001370259.2(MEN1):c.292C>T (p.Arg98Ter)	4221	MEN1	Pathogenic	886039413	RCV000255438\|RCV001244528\|RCV002436089;	N	MedGen:C3661900\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577290	64577290	11:g.64577290G>A	ClinGen:CA10588535	CN517202 not provided;
NM_001370259.2(MEN1):c.288G>A (p.Gln96=)	4221	MEN1	Likely benign	2136185997	RCV002219937;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577294	64577294	64577294	-
NM_001370259.2(MEN1):c.266_286del (p.Leu89_Ala95del)	4221	MEN1	Conflicting interpretations of pathogenicity	1064792906	RCV000460992\|RCV000478848;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:CN517202	11	64577296	64577316	NC_000011.9:g.64577302_64577322del	ClinGen:CA16613478
NM_001370259.2(MEN1):c.286C>T (p.Gln96Ter)	4221	MEN1	Pathogenic	-1	RCV003062410;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577296	64577296	NC_000011.9:g.64577296G>A	-
NM_001370259.2(MEN1):c.280_284dup (p.Gln96fs)	4221	MEN1	Pathogenic	1555166494	RCV000471670;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577297	64577298	NC_000011.9:g.64577299_64577303dup	ClinGen:CA16613482	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.283G>T (p.Ala95Ser)	4221	MEN1	Uncertain significance	1592658740	RCV000817101;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577299	64577299	11:g.64577299C>A	-
NM_001370259.2(MEN1):c.283G>A (p.Ala95Thr)	4221	MEN1	Uncertain significance	-1	RCV002435231\|RCV003102778;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577299	64577299	64577299	-
NM_001370259.2(MEN1):c.282C>T (p.Thr94=)	4221	MEN1	Likely benign	760442763	RCV000206522\|RCV000566889;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577300	64577300	11:g.64577300G>A	ClinGen:CA061057	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.281C>T (p.Thr94Ile)	4221	MEN1	Uncertain significance	1565651820	RCV000701865\|RCV002440514\|RCV003222115;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	11	64577301	64577301	11:g.64577301G>A	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.275G>A (p.Arg92His)	4221	MEN1	Uncertain significance	375628323	RCV001213301\|RCV002436822;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577307	64577307	11:g.64577307C>T	-
NM_001370259.2(MEN1):c.274C>A (p.Arg92Ser)	4221	MEN1	Uncertain significance	1488275961	RCV001106457\|RCV001106458;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|Human Phenotype Ontology:HP:0000843,MONDO:MONDO:0001741,MedGen:C0020502	11	64577308	64577308	11:g.64577308G>T	-
NM_001370259.2(MEN1):c.274C>G (p.Arg92Gly)	4221	MEN1	Uncertain significance	1488275961	RCV001217959;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577308	64577308	11:g.64577308G>C	-
NM_001370259.2(MEN1):c.274C>T (p.Arg92Cys)	4221	MEN1	Uncertain significance	1488275961	RCV001204794;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577308	64577308	11:g.64577308G>A	-
NM_001370259.2(MEN1):c.274del (p.Arg92fs)	4221	MEN1	Likely pathogenic	2136186754	RCV002223017;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577308	64577308	64577307	-
NM_001370259.2(MEN1):c.269_270dup (p.Ala91fs)	4221	MEN1	Pathogenic	1941994887	RCV001043462;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577311	64577312	11:g.64577311_64577312insAT	-
NM_001370259.2(MEN1):c.271G>T (p.Ala91Ser)	4221	MEN1	Uncertain significance	2136186838	RCV002028876\|RCV003170568;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577311	64577311	64577311	-
NM_001370259.2(MEN1):c.269dup (p.Tyr90Ter)	4221	MEN1	Pathogenic	2136187018	RCV001387770;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577312	64577313	64577312	-
NM_001370259.2(MEN1):c.269A>G (p.Tyr90Cys)	4221	MEN1	Uncertain significance	1565651873	RCV000693398;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577313	64577313	11:g.64577313T>C	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.267C>G (p.Leu89=)	4221	MEN1	Likely benign	1060499972	RCV000470195\|RCV002436376;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577315	64577315	NC_000011.9:g.64577315G>C	ClinGen:CA16613483	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.248_266del (p.Leu83fs)	4221	MEN1	Pathogenic	2136187161	RCV001384977;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577316	64577334	64577315	-
NM_001370259.2(MEN1):c.266T>C (p.Leu89Pro)	4221	MEN1	Uncertain significance	2136187120	RCV001881404;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577316	64577316	64577316	-
NM_001370259.2(MEN1):c.265C>T (p.Leu89Phe)	4221	MEN1	Uncertain significance	-1	RCV002810697\|RCV003167806;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577317	64577317	NC_000011.9:g.64577317G>A	-
NM_001370259.2(MEN1):c.263C>G (p.Ala88Gly)	4221	MEN1	Uncertain significance	-1	RCV002838705;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577319	64577319	NC_000011.9:g.64577319G>C	-
NM_001370259.2(MEN1):c.259_260insTCGC (p.Ala87fs)	4221	MEN1	Pathogenic	-1	RCV002872250;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577322	64577323	NC_000011.9:g.64577322_64577323insGCGA	-
NM_001370259.2(MEN1):c.259G>A (p.Ala87Thr)	4221	MEN1	Uncertain significance	-1	RCV003461848;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577323	64577323		-
NM_001370259.2(MEN1):c.258C>T (p.Ile86=)	4221	MEN1	Likely benign	759731868	RCV001016032\|RCV001426905;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577324	64577324	11:g.64577324G>A	-
NM_001370259.2(MEN1):c.252dup (p.Ile85fs)	4221	MEN1	Pathogenic/Likely pathogenic	386134253	RCV000030201;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577329	64577330	11:g.64577329_64577330insA	ClinGen:CA260457	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.252_253insTT (p.Ile85fs)	4221	MEN1	Pathogenic	386134253	RCV000468271;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577329	64577330	NC_000011.9:g.64577330_64577331insAA	ClinGen:CA16613485	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.253A>G (p.Ile85Val)	4221	MEN1	Uncertain significance	-1	RCV003470091;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577329	64577329		-
NM_001370259.2(MEN1):c.249_252del (p.Ile85fs)	4221	MEN1	Pathogenic	587776841	RCV000018173\|RCV000206170\|RCV000182434\|RCV000491114;	N	MedGen:C4017330\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577330	64577333	11:g.64577330_64577333del	ClinGen:CA009345,OMIM:613733.0002,OMIM:613733.0017	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.252T>C (p.Ser84=)	4221	MEN1	Likely benign	1592658989	RCV001505382;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577330	64577330	11:g.64577330A>G	-
NM_001370259.2(MEN1):c.247_249dup (p.Leu83_Ser84insLeu)	4221	MEN1	Uncertain significance	-1	RCV002861410;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577332	64577333	NC_000011.9:g.64577333_64577335dup	-
NM_001370259.2(MEN1):c.249G>A (p.Leu83=)	4221	MEN1	Likely benign	386134252	RCV000030200;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577333	64577333	11:g.64577333C>T	ClinGen:CA009351	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.249G>T (p.Leu83=)	4221	MEN1	Likely benign	386134252	RCV001395035;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577333	64577333	64577333	-
NM_001370259.2(MEN1):c.248T>A (p.Leu83Gln)	4221	MEN1	Uncertain significance	752747097	RCV001040361;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577334	64577334	11:g.64577334A>T	-
NM_001370259.2(MEN1):c.248T>C (p.Leu83Pro)	4221	MEN1	Conflicting interpretations of pathogenicity	752747097	RCV001361208\|RCV003169798;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577334	64577334	64577334	-
NM_001370259.2(MEN1):c.246C>G (p.Asp82Glu)	4221	MEN1	Uncertain significance	1238113583	RCV000557501\|RCV002431542;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577336	64577336	NC_000011.9:g.64577336G>C	ClinGen:CA381187564	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.246C>T (p.Asp82=)	4221	MEN1	Likely benign	1238113583	RCV002170805\|RCV002443107;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577336	64577336	64577336	-
NM_001370259.2(MEN1):c.244G>C (p.Asp82His)	4221	MEN1	Uncertain significance	1419086083	RCV000549380\|RCV002431541;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577338	64577338	NC_000011.9:g.64577338C>G	ClinGen:CA381187571	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.244G>A (p.Asp82Asn)	4221	MEN1	Uncertain significance	1419086083	RCV001300074;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577338	64577338	64577338	-
NM_001370259.2(MEN1):c.244G>T (p.Asp82Tyr)	4221	MEN1	Uncertain significance	-1	RCV003470095;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577338	64577338		-
NM_001370259.2(MEN1):c.243C>T (p.Ala81=)	4221	MEN1	Likely benign	-1	RCV002780370;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577339	64577339		-
NM_001370259.2(MEN1):c.241G>A (p.Ala81Thr)	4221	MEN1	Uncertain significance	2136188110	RCV001954080;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577341	64577341	64577341	-
NM_001370259.2(MEN1):c.241del (p.Ala81fs)	4221	MEN1	Pathogenic	-1	RCV003029164;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577341	64577341	NC_000011.9:g.64577342del	-
NM_001370259.2(MEN1):c.240G>T (p.Val80=)	4221	MEN1	Likely benign	1555166545	RCV000632150;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577342	64577342	11:g.64577342C>A	ClinGen:CA475163770	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.238del (p.Val80fs)	4221	MEN1	Pathogenic	2136188216	RCV001381751;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577344	64577344	64577343	-
NM_001370259.2(MEN1):c.238G>A (p.Val80Met)	4221	MEN1	Uncertain significance	-1	RCV002629633;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577344	64577344	NC_000011.9:g.64577344C>T	-
NM_001370259.2(MEN1):c.237del (p.Val80fs)	4221	MEN1	Pathogenic	1114167486	RCV000491464\|RCV000704558;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577345	64577345	NC_000011.9:g.64577347del	ClinGen:CA475163782	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.237C>T (p.Pro79=)	4221	MEN1	Likely benign	1592659200	RCV001015323\|RCV002068904;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577345	64577345	11:g.64577345G>A	-
NM_001370259.2(MEN1):c.237C>G (p.Pro79=)	4221	MEN1	Likely benign	1592659200	RCV001473443;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577345	64577345	64577345	-
NM_001370259.2(MEN1):c.236C>G (p.Pro79Arg)	4221	MEN1	Uncertain significance	1555166557	RCV000632130;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577346	64577346	11:g.64577346G>C	ClinGen:CA381187585	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.236C>T (p.Pro79Leu)	4221	MEN1	Uncertain significance	1555166557	RCV000804127\|RCV002453782;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577346	64577346	11:g.64577346G>A	-
NM_001370259.2(MEN1):c.234dup (p.Pro79fs)	4221	MEN1	Pathogenic	2136188431	RCV001390533\|RCV003382568;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577347	64577348	64577347	-
NM_001370259.2(MEN1):c.235C>G (p.Pro79Ala)	4221	MEN1	Uncertain significance	-1	RCV003003144;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577347	64577347	NC_000011.9:g.64577347G>C	-
NM_001370259.2(MEN1):c.234T>C (p.Phe78=)	4221	MEN1	Likely benign	2136188387	RCV001503354;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577348	64577348	64577348	-
NM_001370259.2(MEN1):c.234del (p.Val80fs)	4221	MEN1	Pathogenic	2136188431	RCV001917452;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577348	64577348	64577347	-
NM_001370259.2(MEN1):c.231C>G (p.Tyr77Ter)	4221	MEN1	Pathogenic/Likely pathogenic	1555166567	RCV000632123\|RCV002248835\|RCV002448939;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577351	64577351	11:g.64577351G>C	ClinGen:CA381187598	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.230A>G (p.Tyr77Cys)	4221	MEN1	Uncertain significance	-1	RCV002446416\|RCV003101729;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577352	64577352	64577352	-
NM_001370259.2(MEN1):c.228C>T (p.Thr76=)	4221	MEN1	Likely benign	1394017906	RCV001423824\|RCV002445006;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577354	64577354	11:g.64577354G>A	-
NM_001370259.2(MEN1):c.228C>G (p.Thr76=)	4221	MEN1	Likely benign	1394017906	RCV001046976;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577354	64577354	11:g.64577354G>C	-
NM_001370259.2(MEN1):c.227C>A (p.Thr76Asn)	4221	MEN1	Uncertain significance	886039752	RCV000255896\|RCV001246047;	N	MedGen:CN517202\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577355	64577355	11:g.64577355G>T	ClinGen:CA10588536	CN169374 not specified;
NM_001370259.2(MEN1):c.227C>T (p.Thr76Ile)	4221	MEN1	Uncertain significance	-1	RCV002510439\|RCV002569437;	N	MedGen:CN169374\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577355	64577355	NC_000011.9:g.64577355G>A	-
NM_001370259.2(MEN1):c.226A>T (p.Thr76Ser)	4221	MEN1	Uncertain significance	1592659343	RCV001226580\|RCV003346392;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577356	64577356	11:g.64577356T>A	-
NM_001370259.2(MEN1):c.225C>A (p.Leu75=)	4221	MEN1	Likely benign	1333791405	RCV000603478\|RCV001427745;	N	MedGen:CN169374\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577357	64577357	11:g.64577357G>T	ClinGen:CA475163804	CN169374 not specified;
NM_001370259.2(MEN1):c.225C>T (p.Leu75=)	4221	MEN1	Likely benign	1333791405	RCV001436230\|RCV002442837;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577357	64577357	11:g.64577357G>A	-
NM_001370259.2(MEN1):c.220G>T (p.Gly74Cys)	4221	MEN1	Uncertain significance	2136188922	RCV001968176\|RCV003170196;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577362	64577362	64577362	-
NM_001370259.2(MEN1):c.219C>T (p.Gly73=)	4221	MEN1	Likely benign	758434243	RCV001435855\|RCV002432212\|RCV003405663;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	11	64577363	64577363	64577363	-
NM_001370259.2(MEN1):c.219C>A (p.Gly73=)	4221	MEN1	Likely benign	-1	RCV002871928;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577363	64577363		-
NM_001370259.2(MEN1):c.216_217insA (p.Gly73fs)	4221	MEN1	Pathogenic	-1	RCV002815912;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577365	64577366	NC_000011.9:g.64577365_64577366insT	-
NM_001370259.2(MEN1):c.217G>T (p.Gly73Cys)	4221	MEN1	Uncertain significance	-1	RCV002963215;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577365	64577365	NC_000011.9:g.64577365C>A	-
NM_001370259.2(MEN1):c.216T>G (p.Pro72=)	4221	MEN1	Likely benign	1592659467	RCV001409524\|RCV002420914;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577366	64577366	64577366	-
NM_001370259.2(MEN1):c.215C>A (p.Pro72His)	4221	MEN1	Uncertain significance	878856863	RCV000695116\|RCV002422524;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577367	64577367	NC_000011.9:g.64577367G>T	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.215C>T (p.Pro72Leu)	4221	MEN1	Uncertain significance	878856863	RCV001910996;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577367	64577367	64577367	-
NM_001370259.2(MEN1):c.213G>T (p.Pro71=)	4221	MEN1	Likely benign	778154183	RCV002101973\|RCV002427676;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577369	64577369	64577369	-
NM_001370259.2(MEN1):c.213G>A (p.Pro71=)	4221	MEN1	Likely benign	778154183	RCV002114571\|RCV003161591;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577369	64577369	64577369	-
NM_001370259.2(MEN1):c.211_212del (p.Pro71fs)	4221	MEN1	Pathogenic	386134251	RCV000030199\|RCV000182433;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900	11	64577370	64577371	11:g.64577370_64577371del	ClinGen:CA009338	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.211C>T (p.Pro71Ser)	4221	MEN1	Uncertain significance	1592659522	RCV000805744;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577371	64577371	11:g.64577371G>A	-
NM_001370259.2(MEN1):c.210C>A (p.Asp70Glu)	4221	MEN1	Uncertain significance	150308912	RCV000574548\|RCV000796273;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577372	64577372	NC_000011.9:g.64577372G>T	ClinGen:CA061004	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.210C>G (p.Asp70Glu)	4221	MEN1	Uncertain significance	150308912	RCV001982471;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577372	64577372	64577372	-
NM_001370259.2(MEN1):c.208G>T (p.Asp70Tyr)	4221	MEN1	Uncertain significance	1283021293	RCV000792347\|RCV002422678;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577374	64577374	11:g.64577374C>A	-
NM_001370259.2(MEN1):c.208G>A (p.Asp70Asn)	4221	MEN1	Uncertain significance	1283021293	RCV001305245\|RCV002418924;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577374	64577374	64577374	-
NM_001370259.2(MEN1):c.202_206dup (p.Asp70fs)	4221	MEN1	Pathogenic	730882136	RCV000161945\|RCV000182459\|RCV002415705;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577375	64577376	NC_000011.9:g.64577376GGGGC[3]	ClinGen:CA009325	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.207C>A (p.Pro69=)	4221	MEN1	Likely benign	2136189522	RCV001501661;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577375	64577375	64577375	-
NM_001370259.2(MEN1):c.205C>T (p.Pro69Ser)	4221	MEN1	Uncertain significance	1060499995	RCV000461607\|RCV003362788\|RCV003401444;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|	11	64577377	64577377	NC_000011.9:g.64577377G>A	ClinGen:CA16613486	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.204C>A (p.Ala68=)	4221	MEN1	Likely benign	2136189673	RCV002076219\|RCV002416461;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577378	64577378	64577378	-
NM_001370259.2(MEN1):c.204C>T (p.Ala68=)	4221	MEN1	Likely benign	2136189673	RCV002153612;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577378	64577378	64577378	-
NM_001370259.2(MEN1):c.203C>T (p.Ala68Val)	4221	MEN1	Uncertain significance	1319371332	RCV000697108;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577379	64577379	11:g.64577379G>A	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.202G>A (p.Ala68Thr)	4221	MEN1	Uncertain significance	1343345477	RCV000699868\|RCV002422559;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577380	64577380	NC_000011.9:g.64577380C>T	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.201C>T (p.Pro67=)	4221	MEN1	Likely benign	1060503791	RCV000460216\|RCV000563989;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577381	64577381	NC_000011.9:g.64577381G>A	ClinGen:CA16613634	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.196_200dup (p.Asp70fs)	4221	MEN1	Pathogenic	1555166609	RCV000462360\|RCV001269621\|RCV002418346;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577381	64577382	NC_000011.9:g.64577384GCTGG[3]	ClinGen:CA16613636	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.201del (p.Ala68fs)	4221	MEN1	Pathogenic	2136189816	RCV001374378;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577381	64577381	64577380	-
NM_001370259.2(MEN1):c.200C>T (p.Pro67Leu)	4221	MEN1	Likely benign	757766498	RCV001037759;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577382	64577382	11:g.64577382G>A	-
NM_001370259.2(MEN1):c.200C>G (p.Pro67Arg)	4221	MEN1	Uncertain significance	757766498	RCV002017599\|RCV002423231;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577382	64577382	64577382	-
NM_001370259.2(MEN1):c.198C>T (p.Ser66=)	4221	MEN1	Likely benign	2136189969	RCV001408853\|RCV002420911;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577384	64577384	64577384	-
NM_001370259.2(MEN1):c.197G>T (p.Ser66Ile)	4221	MEN1	Uncertain significance	-1	RCV002711270\|RCV003308243;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577385	64577385	NC_000011.9:g.64577385C>A	-
NM_001370259.2(MEN1):c.196A>C (p.Ser66Arg)	4221	MEN1	Uncertain significance	1942005110	RCV001364873\|RCV003298585;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577386	64577386	64577386	-
NM_001370259.2(MEN1):c.195C>A (p.Pro65=)	4221	MEN1	Likely benign	1438097332	RCV000632176;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577387	64577387	11:g.64577387G>T	ClinGen:CA475163864	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.195C>T (p.Pro65=)	4221	MEN1	Likely benign	1438097332	RCV002184214;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577387	64577387	64577387	-
NM_001370259.2(MEN1):c.195del (p.Ser66fs)	4221	MEN1	Pathogenic	-1	RCV002889811;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577387	64577387	NC_000011.9:g.64577389del	-
NM_001370259.2(MEN1):c.194C>A (p.Pro65His)	4221	MEN1	Uncertain significance	1114167484	RCV000491453\|RCV001856928;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577388	64577388	NC_000011.9:g.64577388G>T	ClinGen:CA381187672	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.193C>A (p.Pro65Thr)	4221	MEN1	Uncertain significance	1235900915	RCV000632119;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577389	64577389	NC_000011.9:g.64577389G>T	ClinGen:CA381187675	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.189C>G (p.Phe63Leu)	4221	MEN1	Uncertain significance	137880635	RCV000523092\|RCV000559995\|RCV001013550\|RCV001821464;	N	MedGen:C3661900\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN169374	11	64577393	64577393	11:g.64577393G>C	ClinGen:CA060980	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.189C>T (p.Phe63=)	4221	MEN1	Likely benign	137880635	RCV002088727;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577393	64577393	64577393	-
NM_001370259.2(MEN1):c.188T>A (p.Phe63Tyr)	4221	MEN1	Uncertain significance	1366457977	RCV000820097\|RCV001013466;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577394	64577394	11:g.64577394A>T	-
NM_001370259.2(MEN1):c.184A>C (p.Thr62Pro)	4221	MEN1	Uncertain significance	1555166619	RCV000632143;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577398	64577398	NC_000011.9:g.64577398T>G	ClinGen:CA381187694	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.183C>A (p.Leu61=)	4221	MEN1	Likely benign	1555166622	RCV000632146;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577399	64577399	NC_000011.9:g.64577399G>T	ClinGen:CA475163881	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.180G>A (p.Glu60=)	4221	MEN1	Likely benign	2136190736	RCV002137658\|RCV002409530;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577402	64577402	64577402	-
NM_001370259.2(MEN1):c.179A>G (p.Glu60Gly)	4221	MEN1	Uncertain significance	1942007547	RCV001234671;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577403	64577403	11:g.64577403T>C	-
NM_001370259.2(MEN1):c.178G>A (p.Glu60Lys)	4221	MEN1	Uncertain significance	1174208039	RCV001071121\|RCV002402482;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577404	64577404	11:g.64577404C>T	-
NM_001370259.2(MEN1):c.178G>C (p.Glu60Gln)	4221	MEN1	Uncertain significance	1174208039	RCV001864219\|RCV003289130;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MeSH:D030342,MedGen:C0950123	11	64577404	64577404	64577404	-
NM_001370259.2(MEN1):c.177C>T (p.Pro59=)	4221	MEN1	Uncertain significance	749001511	RCV000632118;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577405	64577405	NC_000011.9:g.64577405G>A	ClinGen:CA475163890	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.177C>G (p.Pro59=)	4221	MEN1	Likely benign	749001511	RCV000679254\|RCV002060848;	N	MedGen:C3661900\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577405	64577405	NC_000011.9:g.64577405G>C	-	CN517202 not provided;
NM_001370259.2(MEN1):c.176C>G (p.Pro59Arg)	4221	MEN1	Uncertain significance	768445858	RCV000809017;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577406	64577406	11:g.64577406G>C	-
NM_001370259.2(MEN1):c.175C>G (p.Pro59Ala)	4221	MEN1	Uncertain significance	1352823623	RCV000632128\|RCV002404748;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577407	64577407	11:g.64577407G>C	ClinGen:CA381187714	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.175C>T (p.Pro59Ser)	4221	MEN1	Uncertain significance	1352823623	RCV001013000\|RCV001860729;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577407	64577407	11:g.64577407G>A	-
NM_001370259.2(MEN1):c.162_173del (p.Thr56_Pro59del)	4221	MEN1	Uncertain significance	-1	RCV003009590;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577409	64577420	NC_000011.9:g.64577410_64577421del	-
NM_001370259.2(MEN1):c.171C>A (p.Asn57Lys)	4221	MEN1	Uncertain significance	1171829753	RCV001012867\|RCV001218098;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577411	64577411	11:g.64577411G>T	-
NM_001370259.2(MEN1):c.171C>T (p.Asn57=)	4221	MEN1	Likely benign	1171829753	RCV002139856\|RCV002400350;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577411	64577411	64577411	-
NM_001370259.2(MEN1):c.168del (p.Asn57fs)	4221	MEN1	Pathogenic/Likely pathogenic	1060499990	RCV000460562\|RCV000486690;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:CN517202	11	64577414	64577414	NC_000011.9:g.64577415del	ClinGen:CA16613697	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.165T>A (p.Pro55=)	4221	MEN1	Likely benign	1060503790	RCV001498825;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577417	64577417	NC_000011.9:g.64577417A>T	ClinGen:CA16613638	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.165T>C (p.Pro55=)	4221	MEN1	Likely benign	1060503790	RCV001482401;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577417	64577417	11:g.64577417A>G	-
NM_001370259.2(MEN1):c.163C>T (p.Pro55Ser)	4221	MEN1	Uncertain significance	-1	RCV003015713;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577419	64577419	NC_000011.9:g.64577419G>A	-
NM_001370259.2(MEN1):c.162C>T (p.Ile54=)	4221	MEN1	Likely benign	1555166662	RCV000562193\|RCV001505816;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577420	64577420	NC_000011.9:g.64577420G>A	ClinGen:CA475163916	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.160del (p.Ile54fs)	4221	MEN1	Pathogenic	-1	RCV002736426;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577422	64577422	NC_000011.9:g.64577422del	-
NM_001370259.2(MEN1):c.159C>T (p.Val53=)	4221	MEN1	Likely benign	1411927545	RCV001407849;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577423	64577423	11:g.64577423G>A	-
NM_001370259.2(MEN1):c.159C>A (p.Val53=)	4221	MEN1	Likely benign	1411927545	RCV001426354;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577423	64577423	64577423	-
NM_001370259.2(MEN1):c.159C>G (p.Val53=)	4221	MEN1	Likely benign	1411927545	RCV001480451;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577423	64577423	64577423	-
NM_001370259.2(MEN1):c.157G>C (p.Val53Leu)	4221	MEN1	Uncertain significance	2136191735	RCV001941308;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577425	64577425	64577425	-
NM_001370259.2(MEN1):c.156C>A (p.Arg52=)	4221	MEN1	Likely benign	1592659960	RCV001451254;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577426	64577426	11:g.64577426G>T	-
NM_001370259.2(MEN1):c.156C>T (p.Arg52=)	4221	MEN1	Likely benign	1592659960	RCV001428860;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577426	64577426	64577426	-
NM_001370259.2(MEN1):c.155G>A (p.Arg52His)	4221	MEN1	Uncertain significance	1942010221	RCV001050537\|RCV002400286;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577427	64577427	11:g.64577427C>T	-
NM_001370259.2(MEN1):c.154C>T (p.Arg52Cys)	4221	MEN1	Uncertain significance	1555166664	RCV000562813\|RCV002530339;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577428	64577428	11:g.64577428G>A	ClinGen:CA381187771	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.154C>G (p.Arg52Gly)	4221	MEN1	Uncertain significance	1555166664	RCV001340367;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577428	64577428	64577428	-
NM_001370259.2(MEN1):c.154C>A (p.Arg52Ser)	4221	MEN1	Uncertain significance	-1	RCV002300432;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577428	64577428	64577428	-
NM_001370259.2(MEN1):c.153C>T (p.Asn51=)	4221	MEN1	Likely benign	1555166669	RCV000527744\|RCV002404382;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577429	64577429	11:g.64577429G>A	ClinGen:CA475163932	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.152dup (p.Asn51fs)	4221	MEN1	Pathogenic	869312167	RCV002002502;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577429	64577430	64577429	-
NM_001370259.2(MEN1):c.153C>G (p.Asn51Lys)	4221	MEN1	Uncertain significance	-1	RCV002837678;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577429	64577429	NC_000011.9:g.64577429G>C	-
NM_001370259.2(MEN1):c.152A>G (p.Asn51Ser)	4221	MEN1	Uncertain significance	1942010838	RCV001239337;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577430	64577430	11:g.64577430T>C	-
NM_001370259.2(MEN1):c.150C>T (p.Val50=)	4221	MEN1	Likely benign	2136192168	RCV002163718\|RCV002391337;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577432	64577432	64577432	-
NM_001370259.2(MEN1):c.148G>A (p.Val50Ile)	4221	MEN1	Uncertain significance	1942011354	RCV001062618;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577434	64577434	11:g.64577434C>T	-
NM_001370259.2(MEN1):c.148G>C (p.Val50Leu)	4221	MEN1	Uncertain significance	1942011354	RCV001898471;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577434	64577434	64577434	-
NM_001370259.2(MEN1):c.146C>T (p.Ala49Val)	4221	MEN1	Uncertain significance	1555166674	RCV000632133\|RCV003380647;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577436	64577436	11:g.64577436G>A	ClinGen:CA381187800	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.145G>A (p.Ala49Thr)	4221	MEN1	Uncertain significance	1942011819	RCV001205296;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577437	64577437	11:g.64577437C>T	-
NM_001370259.2(MEN1):c.145G>T (p.Ala49Ser)	4221	MEN1	Uncertain significance	-1	RCV002627787;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577437	64577437	NC_000011.9:g.64577437C>A	-
NM_001370259.2(MEN1):c.139_143dup (p.Ala49fs)	4221	MEN1	Pathogenic	-1	RCV003040679;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577438	64577439	NC_000011.9:g.64577440_64577444dup	-
NM_001370259.2(MEN1):c.143T>C (p.Leu48Pro)	4221	MEN1	Conflicting interpretations of pathogenicity	1592660057	RCV001011589\|RCV001860673;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577439	64577439	11:g.64577439A>G	-
NM_001370259.2(MEN1):c.142del (p.Leu48fs)	4221	MEN1	Pathogenic	1555166681	RCV000632124;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577440	64577440	NC_000011.9:g.64577440del	ClinGen:CA658797665	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.142C>T (p.Leu48=)	4221	MEN1	Likely benign	2136192593	RCV002208150;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577440	64577440	64577440	-
NM_001370259.2(MEN1):c.137A>C (p.His46Pro)	4221	MEN1	Uncertain significance	2136192730	RCV001999316;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577445	64577445	64577445	-
NM_001370259.2(MEN1):c.137A>T (p.His46Leu)	4221	MEN1	Likely pathogenic	-1	RCV003233050;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577445	64577445		-
NM_001370259.2(MEN1):c.135G>C (p.Glu45Asp)	4221	MEN1	Pathogenic/Likely pathogenic	778670301	RCV000464526\|RCV001011173;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577447	64577447	NC_000011.9:g.64577447C>G	ClinGen:CA16613432	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.135G>A (p.Glu45=)	4221	MEN1	Likely benign	778670301	RCV001490664\|RCV002384808;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577447	64577447	64577447	-
NM_001370259.2(MEN1):c.134A>G (p.Glu45Gly)	4221	MEN1	Pathogenic	1592660101	RCV000796726;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577448	64577448	11:g.64577448T>C	-
NM_001370259.2(MEN1):c.133G>A (p.Glu45Lys)	4221	MEN1	Pathogenic	1114167491	RCV000491351\|RCV000696687;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577449	64577449	NC_000011.9:g.64577449C>T	ClinGen:CA381187857	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.133G>C (p.Glu45Gln)	4221	MEN1	Pathogenic	-1	RCV003058327;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577449	64577449	NC_000011.9:g.64577449C>G	-
NM_001370259.2(MEN1):c.132G>T (p.Val44=)	4221	MEN1	Likely benign	1555166691	RCV000632155;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577450	64577450	NC_000011.9:g.64577450C>A	ClinGen:CA475162946	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.129C>G (p.Phe43Leu)	4221	MEN1	Uncertain significance	1592660139	RCV000815127;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577453	64577453	11:g.64577453G>C	-
NM_001370259.2(MEN1):c.126C>T (p.Gly42=)	4221	MEN1	Likely benign	2136193097	RCV001471189;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577456	64577456	64577456	-
NM_001370259.2(MEN1):c.125G>C (p.Gly42Ala)	4221	MEN1	Pathogenic	1565652689	RCV000802906;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577457	64577457	11:g.64577457C>G	-
NM_001370259.2(MEN1):c.119_124del (p.Val40_Leu41del)	4221	MEN1	Uncertain significance	386134248	RCV000030195\|RCV000722115;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:CN169374	11	64577458	64577463	NC_000011.9:g.64577461_64577466del	ClinGen:CA009063
NM_001370259.2(MEN1):c.124G>A (p.Gly42Ser)	4221	MEN1	Conflicting interpretations of pathogenicity	1942013583	RCV001302220\|RCV001812275;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900	11	64577458	64577458	64577458	-
NM_001370259.2(MEN1):c.108_122dup (p.Leu37_Leu41dup)	4221	MEN1	Uncertain significance	1555166695	RCV000632140;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577459	64577460	11:g.64577459_64577460insAGCACCAAGGAAAGG	ClinGen:CA658797666	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.108_122del (p.Leu37_Leu41del)	4221	MEN1	Pathogenic/Likely pathogenic	1555166695	RCV000491599\|RCV002527049;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577460	64577474	NC_000011.9:g.64577467_64577481del	ClinGen:CA645369572
NM_001370259.2(MEN1):c.121C>T (p.Leu41=)	4221	MEN1	Likely benign	1441672096	RCV001010404\|RCV001427949;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577461	64577461	11:g.64577461G>A	-
NM_001370259.2(MEN1):c.120G>T (p.Val40=)	4221	MEN1	Likely benign	1306316325	RCV001478208;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577462	64577462	11:g.64577462C>A	-
NM_001370259.2(MEN1):c.117_118del (p.Leu39fs)	4221	MEN1	Pathogenic	2136193574	RCV001384373;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577464	64577465	64577463	-
NM_001370259.2(MEN1):c.117G>A (p.Leu39=)	4221	MEN1	Uncertain significance	2136193601	RCV001872788;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577465	64577465	64577465	-
NM_001370259.2(MEN1):c.115T>C (p.Leu39=)	4221	MEN1	Likely benign	863224438	RCV000195578\|RCV001010026;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577467	64577467	11:g.64577467A>G	ClinGen:CA335778	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.114C>G (p.Ser38=)	4221	MEN1	Likely benign	1252317486	RCV000533537\|RCV002456059;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577468	64577468	NC_000011.9:g.64577468G>C	ClinGen:CA475163013	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.113C>T (p.Ser38Phe)	4221	MEN1	Pathogenic/Likely pathogenic	794728616	RCV000491203\|RCV000632104;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577469	64577469	NC_000011.9:g.64577469G>A	ClinGen:CA009043	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.108C>G (p.Leu36=)	4221	MEN1	Likely benign	1592660352	RCV001493987;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577474	64577474	11:g.64577474G>C	-
NM_001370259.2(MEN1):c.108C>T (p.Leu36=)	4221	MEN1	Likely benign	-1	RCV002909092;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577474	64577474		-
NM_001370259.2(MEN1):c.105dup (p.Leu36fs)	4221	MEN1	Pathogenic	1555166711	RCV000486614\|RCV001851251;	N	MedGen:CN517202\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577476	64577477	NC_000011.9:g.64577477dup	ClinGen:CA16619368	CN517202 not provided;
NM_001370259.2(MEN1):c.103G>C (p.Val35Leu)	4221	MEN1	Uncertain significance	-1	RCV003047426;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577479	64577479	NC_000011.9:g.64577479C>G	-
NM_001370259.2(MEN1):c.102G>A (p.Leu34=)	4221	MEN1	Likely benign	1255708093	RCV001402881\|RCV002382145;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577480	64577480	11:g.64577480C>T	-
NM_001370259.2(MEN1):c.102G>C (p.Leu34=)	4221	MEN1	Likely benign	1255708093	RCV001490151\|RCV002255674;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577480	64577480	64577480	-
NM_001370259.2(MEN1):c.100C>A (p.Leu34Met)	4221	MEN1	Uncertain significance	771554497	RCV000229989\|RCV000492008;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577482	64577482	NC_000011.9:g.64577482G>T	ClinGen:CA10582947	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.100C>T (p.Leu34=)	4221	MEN1	Likely benign	771554497	RCV000632162;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577482	64577482	NC_000011.9:g.64577482G>A	ClinGen:CA059683	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.99C>T (p.Asp33=)	4221	MEN1	Likely benign	-1	RCV002839220;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577483	64577483		-
NM_001370259.2(MEN1):c.99C>G (p.Asp33Glu)	4221	MEN1	Uncertain significance	-1	RCV003023285;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577483	64577483	NC_000011.9:g.64577483G>C	-
NM_001370259.2(MEN1):c.96G>A (p.Pro32=)	4221	MEN1	Likely benign	1268807885	RCV001470858;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577486	64577486	64577486	-
NM_001370259.2(MEN1):c.95C>T (p.Pro32Leu)	4221	MEN1	Uncertain significance	2136194414	RCV001930980\|RCV002386734;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577487	64577487	64577487	-
NM_001370259.2(MEN1):c.95C>G (p.Pro32Arg)	4221	MEN1	Conflicting interpretations of pathogenicity	-1	RCV002385283\|RCV003094838;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577487	64577487	64577487	-
NM_001370259.2(MEN1):c.94C>T (p.Pro32Ser)	4221	MEN1	Conflicting interpretations of pathogenicity	773089218	RCV000463945\|RCV000562829\|RCV003329276;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	11	64577488	64577488	NC_000011.9:g.64577488G>A	ClinGen:CA061878	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.92A>T (p.Glu31Val)	4221	MEN1	Uncertain significance	1060499977	RCV000458419\|RCV001019129;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577490	64577490	NC_000011.9:g.64577490T>A	ClinGen:CA16613698	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.92A>G (p.Glu31Gly)	4221	MEN1	Uncertain significance	1060499977	RCV000632084;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577490	64577490	11:g.64577490T>C	ClinGen:CA381188001	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.91G>A (p.Glu31Lys)	4221	MEN1	Uncertain significance	1942017514	RCV001238297;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577491	64577491	11:g.64577491C>T	-
NM_001370259.2(MEN1):c.89A>G (p.Glu30Gly)	4221	MEN1	Conflicting interpretations of pathogenicity	1942017685	RCV001294396\|RCV002375337;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577493	64577493	64577493	-
NM_001370259.2(MEN1):c.88G>A (p.Glu30Lys)	4221	MEN1	Uncertain significance	2136194576	RCV002041388\|RCV003299031;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577494	64577494	64577494	-
NM_001370259.2(MEN1):c.87A>C (p.Arg29=)	4221	MEN1	Likely benign	1198070818	RCV000632158\|RCV003162807;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577495	64577495	NC_000011.9:g.64577495T>G	ClinGen:CA475163090	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.85C>T (p.Arg29Ter)	4221	MEN1	Pathogenic	794728615	RCV000474533\|RCV000491222;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577497	64577497	NC_000011.9:g.64577497G>A	ClinGen:CA009645	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.85C>G (p.Arg29Gly)	4221	MEN1	Uncertain significance	794728615	RCV001303630\|RCV002447301;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577497	64577497	64577497	-
NM_001370259.2(MEN1):c.85C>A (p.Arg29=)	4221	MEN1	Likely benign	794728615	RCV002168427;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577497	64577497	64577497	-
NM_001370259.2(MEN1):c.84C>T (p.Gly28=)	4221	MEN1	Likely benign	2136194730	RCV002196156;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577498	64577498	64577498	-
NM_001370259.2(MEN1):c.82_83delinsAA (p.Gly28Asn)	4221	MEN1	Uncertain significance	-1	RCV003011805;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577499	64577500	NC_000011.9:g.64577499_64577500delinsTT	-
NM_001370259.2(MEN1):c.82G>A (p.Gly28Ser)	4221	MEN1	Uncertain significance	953827589	RCV001054889\|RCV003160439;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577500	64577500	11:g.64577500C>T	-
NM_001370259.2(MEN1):c.82G>C (p.Gly28Arg)	4221	MEN1	Uncertain significance	953827589	RCV001327130\|RCV002431933;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577500	64577500	64577500	-
NM_001370259.2(MEN1):c.81G>C (p.Leu27=)	4221	MEN1	Likely benign	1592660553	RCV002064804\|RCV002427205;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577501	64577501	11:g.64577501C>G	-
NM_001370259.2(MEN1):c.81G>T (p.Leu27=)	4221	MEN1	Likely benign	-1	RCV002867218;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577501	64577501		-
NM_001370259.2(MEN1):c.79C>T (p.Leu27=)	4221	MEN1	Likely benign	1006536599	RCV001429118\|RCV002416068;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577503	64577503	11:g.64577503G>A	-
NM_001370259.2(MEN1):c.79C>G (p.Leu27Val)	4221	MEN1	Uncertain significance	1006536599	RCV001039845;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577503	64577503	11:g.64577503G>C	-
NM_001370259.2(MEN1):c.76G>A (p.Glu26Lys)	4221	MEN1	Pathogenic/Likely pathogenic	28931612	RCV000018169\|RCV000490040\|RCV000817082;	N	MedGen:C2675664\|MedGen:CN517202\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577506	64577506	NC_000011.9:g.64577506C>T	ClinGen:CA009584,UniProtKB:O00255#VAR_005427,OMIM:613733.0013	CN517202 not provided;
NM_001370259.2(MEN1):c.75C>T (p.Ala25=)	4221	MEN1	Likely benign	1399788808	RCV001446786\|RCV002396032;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577507	64577507	64577507	-
NM_001370259.2(MEN1):c.74C>T (p.Ala25Val)	4221	MEN1	Uncertain significance	1462138625	RCV000707173;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577508	64577508	NC_000011.9:g.64577508G>A	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.71C>T (p.Ala24Val)	4221	MEN1	Uncertain significance	1328062930	RCV000632091\|RCV002377360;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577511	64577511	NC_000011.9:g.64577511G>A	ClinGen:CA381188076	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.65T>G (p.Leu22Arg)	4221	MEN1	Pathogenic/Likely pathogenic	104894256	RCV000018157\|RCV000182402;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:CN517202	11	64577517	64577517	11:g.64577517A>C	ClinGen:CA009546,UniProtKB:O00255#VAR_005426,OMIM:613733.0001	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.65T>C (p.Leu22Pro)	4221	MEN1	Uncertain significance	104894256	RCV001055011;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577517	64577517	11:g.64577517A>G	-
NM_001370259.2(MEN1):c.64C>T (p.Leu22=)	4221	MEN1	Likely benign	1592660695	RCV001477371;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577518	64577518	11:g.64577518G>A	-
NM_001370259.2(MEN1):c.63C>T (p.Arg21=)	4221	MEN1	Likely benign	1018289242	RCV001025224\|RCV001471473;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577519	64577519	11:g.64577519G>A	-
NM_001370259.2(MEN1):c.61C>A (p.Arg21Ser)	4221	MEN1	Conflicting interpretations of pathogenicity	541476418	RCV000396094\|RCV000563926\|RCV000864930\|RCV001770241;	N	Human Phenotype Ontology:HP:0000843,MONDO:MONDO:0001741,MedGen:C0020502\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900	11	64577521	64577521	11:g.64577521G>T	ClinGen:CA061326	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.61C>G (p.Arg21Gly)	4221	MEN1	Uncertain significance	541476418	RCV000477155;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577521	64577521	NC_000011.9:g.64577521G>C	ClinGen:CA16613641	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.61C>T (p.Arg21Cys)	4221	MEN1	Uncertain significance	541476418	RCV001302367;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577521	64577521	64577521	-
NM_001370259.2(MEN1):c.60G>C (p.Val20=)	4221	MEN1	Likely benign	776432516	RCV000244620\|RCV000470194\|RCV002356342;	N	MedGen:CN169374\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577522	64577522	NC_000011.9:g.64577522C>G	ClinGen:CA10587133	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.60G>A (p.Val20=)	4221	MEN1	Likely benign	-1	RCV002715192;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577522	64577522		-
NM_001370259.2(MEN1):c.58G>T (p.Val20Leu)	4221	MEN1	Uncertain significance	1942022491	RCV001207909;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577524	64577524	11:g.64577524C>A	-
NM_001370259.2(MEN1):c.57G>A (p.Val19=)	4221	MEN1	Conflicting interpretations of pathogenicity	759282395	RCV001248632\|RCV002357056;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577525	64577525	11:g.64577525C>T	-
NM_001370259.2(MEN1):c.54C>T (p.Asp18=)	4221	MEN1	Likely benign	1316973259	RCV000532778;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577528	64577528	NC_000011.9:g.64577528G>A	ClinGen:CA475163211	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.52G>T (p.Asp18Tyr)	4221	MEN1	Uncertain significance	2136195598	RCV001926002;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577530	64577530	64577530	-
NM_001370259.2(MEN1):c.51C>T (p.Asp17=)	4221	MEN1	Likely benign	2136195633	RCV001473459;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577531	64577531	64577531	-
NM_001370259.2(MEN1):c.50A>G (p.Asp17Gly)	4221	MEN1	Uncertain significance	1157581823	RCV001224295\|RCV003380903;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577532	64577532	11:g.64577532T>C	-
NM_001370259.2(MEN1):c.49G>A (p.Asp17Asn)	4221	MEN1	Uncertain significance	1399824473	RCV000632125\|RCV001023389;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577533	64577533	NC_000011.9:g.64577533C>T	ClinGen:CA381188174	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.48C>T (p.Ile16=)	4221	MEN1	Likely benign	1060503797	RCV001504106\|RCV003278821;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577534	64577534	NC_000011.9:g.64577534G>A	ClinGen:CA16613487	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.44C>G (p.Ser15Cys)	4221	MEN1	Uncertain significance	1056705868	RCV001022586\|RCV003467666;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577538	64577538	11:g.64577538G>C	-
NM_001370259.2(MEN1):c.44C>T (p.Ser15Phe)	4221	MEN1	Uncertain significance	1056705868	RCV001043539;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577538	64577538	11:g.64577538G>A	-
NM_001370259.2(MEN1):c.42C>G (p.Arg14=)	4221	MEN1	Likely benign	765446407	RCV001416376;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577540	64577540	64577540	-
NM_001370259.2(MEN1):c.41_42delinsT (p.Arg14fs)	4221	MEN1	Pathogenic	-1	RCV003033376;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577540	64577541	NC_000011.9:g.64577540_64577541delinsA	-
NM_001370259.2(MEN1):c.40C>T (p.Arg14Cys)	4221	MEN1	Uncertain significance	1209178117	RCV000797298\|RCV002325521;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577542	64577542	11:g.64577542G>A	-
NM_001370259.2(MEN1):c.38T>G (p.Leu13Arg)	4221	MEN1	Uncertain significance	1262285748	RCV000694774;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577544	64577544	NC_000011.9:g.64577544A>C	-	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.38T>C (p.Leu13Pro)	4221	MEN1	Uncertain significance	1262285748	RCV000803145;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577544	64577544	11:g.64577544A>G	-
NM_001370259.2(MEN1):c.36G>T (p.Pro12=)	4221	MEN1	Likely benign	775721366	RCV000978248\|RCV003307773;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577546	64577546	11:g.64577546C>A	-
NM_001370259.2(MEN1):c.36G>A (p.Pro12=)	4221	MEN1	Likely benign	775721366	RCV001481253\|RCV002350983;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577546	64577546	64577546	-
NM_001370259.2(MEN1):c.35C>T (p.Pro12Leu)	4221	MEN1	Likely pathogenic	794728614	RCV000538512;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577547	64577547	NC_000011.9:g.64577547G>A	ClinGen:CA009390,UniProtKB:O00255#VAR_005425	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.33C>G (p.Phe11Leu)	4221	MEN1	Uncertain significance	-1	RCV002452020\|RCV003099455;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577549	64577549	64577549	-
NM_001370259.2(MEN1):c.30G>T (p.Leu10=)	4221	MEN1	Conflicting interpretations of pathogenicity	371192390	RCV000123385\|RCV000491878\|RCV000609004\|RCV000757460\|RCV001108653;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN169374\|MedGen:C3661900\|Human Phenotype Ontology:HP:0000843,MONDO:MONDO:0001741,MedGen:C0020502	11	64577552	64577552	NC_000011.9:g.64577552C>A	ClinGen:CA009365	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.29T>G (p.Leu10Arg)	4221	MEN1	Uncertain significance	1942026011	RCV001227378\|RCV003294087;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577553	64577553	11:g.64577553A>C	-
NM_001370259.2(MEN1):c.29T>C (p.Leu10Pro)	4221	MEN1	Uncertain significance	-1	RCV003049771;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577553	64577553	NC_000011.9:g.64577553A>G	-
NM_001370259.2(MEN1):c.28C>T (p.Leu10=)	4221	MEN1	Likely benign	2136196333	RCV002216387;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577554	64577554	64577554	-
NM_001370259.2(MEN1):c.27G>A (p.Thr9=)	4221	MEN1	Likely benign	1190267704	RCV001417881\|RCV002438973;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577555	64577555	64577555	-
NM_001370259.2(MEN1):c.24G>A (p.Lys8=)	4221	MEN1	Likely benign	2136196440	RCV002159841;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577558	64577558	64577558	-
NC_000011.9:g.(?_64577559)_(64578852_?)del	4221	MEN1	Pathogenic	-1	RCV003123030;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577559	64578852		-
NM_001370259.2(MEN1):c.22A>G (p.Lys8Glu)	4221	MEN1	Uncertain significance	1942026565	RCV001210328;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577560	64577560	11:g.64577560T>C	-
NM_001370259.2(MEN1):c.21G>A (p.Gln7=)	4221	MEN1	Conflicting interpretations of pathogenicity	1422628649	RCV000864258\|RCV001014748;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577561	64577561	11:g.64577561C>T	-
NM_001370259.2(MEN1):c.18C>T (p.Ala6=)	4221	MEN1	Benign/Likely benign	369348210	RCV000195439\|RCV000565891\|RCV001705156;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:C3661900	11	64577564	64577564	NC_000011.9:g.64577564G>A	ClinGen:CA060984	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.16_17del (p.Ala6fs)	4221	MEN1	Pathogenic	1114167523	RCV000491928\|RCV001229975;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577565	64577566	NC_000011.9:g.64577566_64577567del	ClinGen:CA645369576	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.17C>T (p.Ala6Val)	4221	MEN1	Uncertain significance	-1	RCV002627781;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577565	64577565	NC_000011.9:g.64577565G>A	-
NM_001370259.2(MEN1):c.16G>T (p.Ala6Ser)	4221	MEN1	Uncertain significance	966793401	RCV000565141\|RCV000632111;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577566	64577566	11:g.64577566C>A	ClinGen:CA223917347	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.16G>A (p.Ala6Thr)	4221	MEN1	Uncertain significance	966793401	RCV001012794\|RCV001222652;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577566	64577566	11:g.64577566C>T	-
NM_001370259.2(MEN1):c.15C>A (p.Ala5=)	4221	MEN1	Likely benign	757821521	RCV000473276\|RCV001012305;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577567	64577567	NC_000011.9:g.64577567G>T	ClinGen:CA16613493	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.14C>G (p.Ala5Gly)	4221	MEN1	Uncertain significance	2136196896	RCV002037474;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577568	64577568	64577568	-
NM_001370259.2(MEN1):c.11A>C (p.Lys4Thr)	4221	MEN1	Uncertain significance	1592661250	RCV000793073\|RCV003307425;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577571	64577571	11:g.64577571T>G	-
NM_001370259.2(MEN1):c.6dup (p.Leu3fs)	4221	MEN1	Pathogenic	2136197117	RCV001383274;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577575	64577576	64577575	-
NM_001370259.2(MEN1):c.6del (p.Gly2_Leu3insTer)	4221	MEN1	Pathogenic	2136197117	RCV001939358\|RCV002361298;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577576	64577576	64577575	-
NM_001370259.2(MEN1):c.5G>A (p.Gly2Glu)	4221	MEN1	Uncertain significance	1592661296	RCV000800118;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577577	64577577	11:g.64577577C>T	-
NM_001370259.2(MEN1):c.3G>A (p.Met1Ile)	4221	MEN1	Pathogenic/Likely pathogenic	786204242	RCV000168423\|RCV001556584\|RCV002372056;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577579	64577579	NC_000011.9:g.64577579C>T	ClinGen:CA009394	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.2T>A (p.Met1Lys)	4221	MEN1	Pathogenic	-1	RCV003058328;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577580	64577580	NC_000011.9:g.64577580A>T	-
NM_001370259.2(MEN1):c.1A>G (p.Met1Val)	4221	MEN1	Pathogenic/Likely pathogenic	386134250	RCV000030198\|RCV000480514\|RCV000491918\|RCV000508430;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MedGen:CN169374	11	64577581	64577581	NC_000011.9:g.64577581T>C	ClinGen:CA009318	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1A>T (p.Met1Leu)	4221	MEN1	Pathogenic	386134250	RCV000491567\|RCV000536890;	N	MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577581	64577581	NC_000011.9:g.64577581T>A	ClinGen:CA381188344	C0027672 Hereditary cancer-predisposing syndrome;
NM_001370259.2(MEN1):c.1A>C (p.Met1Leu)	4221	MEN1	Pathogenic	386134250	RCV001055158\|RCV003380824;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577581	64577581	11:g.64577581T>G	-
NM_001370259.2(MEN1):c.-2C>T	4221	MEN1	Uncertain significance	653534	RCV000206434\|RCV002433902;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577583	64577583	NC_000011.9:g.64577583G>A	ClinGen:CA350468	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.-6G>A	4221	MEN1	Conflicting interpretations of pathogenicity	768088337	RCV001334472\|RCV001796447\|RCV001820028\|RCV002368113;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:C3661900\|MedGen:CN169374\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577587	64577587	64577587	-
NM_001370259.2(MEN1):c.-20G>A	4221	MEN1	Conflicting interpretations of pathogenicity	386134244	RCV000030190\|RCV000480991\|RCV002415435;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:CN169374\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577601	64577601	11:g.64577601C>T	ClinGen:CA009331	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.-22C>A	4221	MEN1	Conflicting interpretations of pathogenicity	374749001	RCV000225942\|RCV000454537\|RCV000679245\|RCV002258863;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:CN169374\|MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162	11	64577603	64577603	11:g.64577603G>T	ClinGen:CA061014	C0025267 131100 Multiple endocrine neoplasia, type 1;
NM_001370259.2(MEN1):c.-23-135G>A	4221	MEN1	Uncertain significance	587777949	RCV000122413\|RCV001294052;	N	MedGen:CN169374\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577739	64577739	11:g.64577739C>T	ClinGen:CA009341	CN169374 not specified;
NM_001370259.2(MEN1):c.-24+84C>G	4221	MEN1	Likely benign	568093485	RCV000988575;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64577902	64577902	11:g.64577902G>C	-
NM_000244.4(MEN1):c.-35A>T	4221	MEN1	Benign	679946	RCV000314220\|RCV000368660\|RCV000417914;	N	Human Phenotype Ontology:HP:0000843,MONDO:MONDO:0001741,MedGen:C0020502\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:CN169374	11	64578113	64578113	11:g.64578113T>A	ClinGen:CA10635266	C0020502 Hyperparathyroidism;
NM_000244.4(MEN1):c.-35A>C	4221	MEN1	Benign	679946	RCV000274018\|RCV000310348\|RCV000426448;	N	Human Phenotype Ontology:HP:0000843,MONDO:MONDO:0001741,MedGen:C0020502\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MedGen:CN169374	11	64578113	64578113	11:g.64578113T>G	ClinGen:CA10639645	C0020502 Hyperparathyroidism;
NM_000244.4(MEN1):c.-47A>G	4221	MEN1	Likely benign	1035192873	RCV000988576;	N	MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64578125	64578125	11:g.64578125T>C	-
NM_130799.2(MEN1):c.-94G>A	4221	MEN1	Uncertain significance	886048480	RCV000270673\|RCV000364998;	N	Human Phenotype Ontology:HP:0000843,MONDO:MONDO:0001741,MedGen:C0020502\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	11	64578172	64578172	11:g.64578172C>T	ClinGen:CA10639646	C0020502 Hyperparathyroidism;
NM_020975.6(RET):c.1826G>A (p.Cys609Tyr)	5979	RET	Pathogenic	77939446	RCV000014958\|RCV000082049\|RCV000173889\|RCV000168107\|RCV000424503\|RCV000444552\|RCV000431942\|RCV000441078\|RCV000496009\|RCV000509116\|RCV000562113\|RCV003415703\|RCV003460480;	N	MedGen:C4016286\|MedGen:C3661900\|MONDO:MONDO:0008234,MeSH:D018813,MedGen:C0025268,OMIM:171400, Orphanet:247698, Orphanet:653\|MONDO:MONDO:0019003,MedGen:C4048306, Orphanet:653\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MO	10	43609070	43609070	10:g.43609070G>A	ClinGen:CA007824,UniProtKB:P07949#VAR_006306,OMIM:164761.0029	C1833921 155240 Familial medullary thyroid carcinoma;
NM_020975.6(RET):c.1888T>C (p.Cys630Arg)	5979	RET	Pathogenic	377767404	RCV000418588\|RCV000429498\|RCV000428845\|RCV000440788\|RCV000436253\|RCV000654593;	N	MONDO:MONDO:0012552,MedGen:C1970712,OMIM:610755, Orphanet:276152\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0008082,MeSH:D018814,MedGen:C0025269,OMIM:162300, Orphanet:247709, Orphanet:653\|Human Phenotype Ontology:	10	43609936	43609936	10:g.43609936T>C	ClinGen:CA008145	C0238462 Medullary thyroid carcinoma;
NM_020975.6(RET):c.2410G>C (p.Val804Leu)	5979	RET	Pathogenic	79658334	RCV000021853\|RCV000419916\|RCV000426266\|RCV000425568\|RCV000436948\|RCV000437130\|RCV000479688\|RCV002453279\|RCV003226171;	N	MONDO:MONDO:0019003,MedGen:C4048306, Orphanet:653\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|MONDO:MONDO:0008234,MeSH:D018813,MedGen:C0025268,OMIM:171400, Orphanet:247698, Orphanet:653\|MONDO:MONDO:0008082,MeSH:D018814,MedGen:	10	43614996	43614996	10:g.43614996G>C	UniProtKB:P07949#VAR_006336,ClinGen:CA008758	C0238462 Medullary thyroid carcinoma;
NM_020975.6(RET):c.2647_2648delinsTT (p.Ala883Phe)	5979	RET	Pathogenic/Likely pathogenic	377767429	RCV000021873\|RCV000426500\|RCV000422001\|RCV000433892\|RCV000445104\|RCV002514127\|RCV003298037;	N	MONDO:MONDO:0008082,MeSH:D018814,MedGen:C0025269,OMIM:162300, Orphanet:247709, Orphanet:653\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652\|Human Phenotype Ontology:HP:0002865,MONDO:MONDO:0015277,MeSH:C536914,MedGen:C0238462,Orph	10	43615568	43615569	NC_000010.10:g.43615568_43615569delinsTT	ClinGen:CA008962	C0238462 Medullary thyroid carcinoma;
NM_000455.5(STK11):c.749C>T (p.Thr250Met)	6794	STK11	Uncertain significance	876661238	RCV000219622\|RCV001184310\|RCV001808582\|RCV003328099;	N	MedGen:C3661900\|MONDO:MONDO:0015356,MeSH:D009386,MedGen:C0027672, Orphanet:140162\|MONDO:MONDO:0008280,MeSH:D010580,MedGen:C0031269,OMIM:175200, Orphanet:2869\|MONDO:MONDO:0007540,MeSH:D018761,MedGen:C0025267,OMIM:131100, Orphanet:652	19	1221226	1221226	NC_000019.9:g.1221226C>T	ClinGen:CA10577596	CN169374 not specified;

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