Disease Browser
Parent Node: Endocrine Gland Neoplasms (D004701) Parent Node: Neoplasms, Multiple Primary (D009378) Parent Node: Neoplastic Syndromes, Hereditary (D009386) ..Starting node .. Multiple Endocrine Neoplasia (D009377) Child Nodes:
........Multiple Endocrine Neoplasia Type 1 (D018761) ........Multiple Endocrine Neoplasia Type 2a (D018813) 1 ........Multiple Endocrine Neoplasia Type 2b (D018814) 1 ........Multiple Endocrine Neoplasia, Type IV (C567059) Sister Nodes: ..Adenomatous Polyposis Coli (D011125) 10 ..Basal Cell Nevus Syndrome (D001478) 1 ..Birt-Hogg-Dube Syndrome (D058249) ..Cancer, Familial, with In Vitro Radioresistance (C566179) ..Collagenoma, Familial Cutaneous (C562925) ..Colorectal Neoplasms, Hereditary Nonpolyposis (D003123) 10 ..Diaphyseal medullary stenosis with malignant fibrous histiocytoma (C536169) ..Dysplastic Nevus Syndrome (D004416) ..Exostoses, Multiple Hereditary (D005097) 14 ..Familial cylindromatosis (C536611) ..Genochondromatosis (C563215) ..Hamartoma Syndrome, Multiple (D006223) 10 ..Hemangioma, capillary infantile (C535860) ..Hereditary Breast and Ovarian Cancer Syndrome (D061325) ..Hereditary leiomyomatosis and renal cell cancer (C535516) ..Juvenile polyposis syndrome (C537702) ..Li-Fraumeni Syndrome (D016864) 4 ..Melanoma-Pancreatic Cancer Syndrome (C563985) ..Meningioma, familial (C537443) ..Multiple Endocrine Neoplasia (D009377) 6 ..Myelocytic leukemia-like syndrome, familial, chronic (C536093) ..Neurofibromatoses (D017253) 13 C:1 ..Paragangliomas 2 (C566646) ..Paragangliomas 3 (C565335) ..Peutz-Jeghers Syndrome (D010580) ..Prostate Cancer, Hereditary, 12 (C567510) ..Tuberous Sclerosis (D014402) 4 ..Turcot syndrome (C536928) ..Wilms Tumor (D009396) 10 Human Disease MESH is developed by UMLS . Further data from MedGen , OMIM ,ClinVar , CTD
Term ID: 8253
Name: Multiple Endocrine Neoplasia
Definition: A group of autosomal dominant diseases characterized by the combined occurrence of tumors involving two or more ENDOCRINE GLANDS that secrete PEPTIDE HORMONES or AMINES. These neoplasias are often benign but can be malignant. They are classified by the endocrine glands involved and the degree of aggressiveness. The two major forms are MEN1 and MEN2 with gene mutations on CHROMOSOME 11 and CHROMOSOME 10, respectively.
Alternative IDs:
ParentIDs: MESH:D004701|MESH:D009378|MESH:D009386
TreeNumbers: C04.588.322.400 |C04.651.600 |C04.700.630 |C16.320.700.630 |C19.344.400
Synonyms: Adenomatoses, Familial Endocrine |Adenomatoses, Multiple Endocrine |Adenomatosis, Familial Endocrine |Adenomatosis, Multiple Endocrine |Adenopathies, Multiple Endocrine |Adenopathy, Multiple Endocrine |Endocrine Adenomatoses, Familial |Endocrine Adenomatoses, M
Slim Mappings: Cancer|Endocrine system disease|Genetic disease (inborn)
Reference:
MedGen: D009377
MeSH: D009377
OMIM: MSeqDR : Genes: Phenotypes Disease Causing ClinVar Variants MSeqDR Portal