Human Phenotype Ontology

Hello! Guest! Please Login or Register! Clinician Mode

Examples Gene: MT-ND1, POLG, Region: M:1-1000 Variant: m.8993T>G, 1:g.10042757T>C rs3888511 MSCV_0000006, ClinVar: RCV000000015, Disease: Leigh syndrome, Phenotype: Retinopathy

Grandparent Node:
Abnormality of dental eruption (HP:0006292)

Parent Node:
Eruption failure (HP:0000706)

..Starting node
..Failure of eruption of permanent teeth (HP:0006352)

Term ID:

6352

Name:

Failure of eruption of permanent teeth

Synonym:

Failure of eruption of adult teeth; Unerupted adult dentition; Unerupted adult teeth; Unerupted permanent dentition; Unerupted permanent teeth

Definition:

Lack of tooth eruption of the secondary dentition.

Comments:

Reference:

HP:0006352

Genes and Diseases:

Child Nodes:

Sister Nodes:

Impacted tooth (HP:0011079)

Multiple unerupted teeth (HP:0006283)

Input	HPO ID	HPO term	Distance	Gene	Gene id entrez	HGNC ID	DiseaseId	DiseaseName	Frequency	ClinVar variants
HPO disease - gene - phenotype typical associations:
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0006352	HP:0006352	Failure of eruption of permanent teeth	0	FLNB CL E G H	2317	3755	OMIM:272460	Spondylocarpotarsal synostosis syndrome	.	233
HP:0006352	HP:0006352	Failure of eruption of permanent teeth	0	MAP3K7 CL E G H	6885	6859	ORPHA:3238	Cardiospondylocarpofacial syndrome	HP:0040282 - Frequent	11
HP:0006352	HP:0006352	Failure of eruption of permanent teeth	0	PTH1R CL E G H	5745	9608	OMIM:125350	Dental noneruption	.	58
HP:0006352	HP:0006352	Failure of eruption of permanent teeth	0	SMCHD1 CL E G H	23347	29090	ORPHA:2250	Hyposmia-nasal and ocular hypoplasia-hypogonadotropic hypogonadism syndrome	HP:0040281 - Very frequent	174
HP:0006352	HP:0006352	Failure of eruption of permanent teeth	0	TCF4 CL E G H	6925	11634	ORPHA:2896	Pitt-Hopkins syndrome	HP:0040281 - Very frequent	241

Genes (5) :FLNB MAP3K7 PTH1R SMCHD1 TCF4

Diseases (5) :OMIM:272460 ORPHA:3238 OMIM:125350 ORPHA:2250 ORPHA:2896

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.