Disease browser and phenotype portal

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MSeqDR-LSDB
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Examples Gene: MT-ND1, POLG, Region: M:1-1000 Variant: m.8993T>G, 1:g.10042757T>C rs3888511 MSCV_0000006, ClinVar: RCV000000015, Disease: Leigh syndrome, Phenotype: Retinopathy

Hearing Loss Disease Portal

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Most Common: Hearing Loss (D034381), Deafness (D003638), Sensorineural HL (D006319), Waardenburg Syndrome, Usher Syndromes

Disease Browser
Parent Node: Pathologic Processes (D010335)
..Starting node ..Nerve Degeneration (D009410)
Child Nodes:
........Cerebellar degeneration, subacute (C535352)
........Retrograde Degeneration (D012183)
........Skeletal Dysplasia And Progressive Central Nervous System Degeneration, Lethal (C566514)
........Striatal Degeneration, Autosomal Dominant (C563783)
........Subacute Combined Degeneration (D052879)
........Wallerian Degeneration (D014855) 1
Sister Nodes:
..Acantholysis (D000051) 1
..Arrhythmias, Cardiac (D001145) 112
..Ascites (D001201)
..Atrial Remodeling (D064752)
..Azotemia (D053099)
..Cardiotoxicity (D066126)
..Channelopathies (D053447) 1
..Chromosome Aberrations (D002869) 271
..Death (D003643) 27
..Dehydration (D003681)
..Delayed Graft Function (D051799)
..Disease (D004194) 1
..Disease Attributes (D020969) 171
..Dysbiosis (D064806)
..Emphysema (D004646) 6
..Extravasation of Diagnostic and Therapeutic Materials (D005119)
..Femoracetabular Impingement (D057925)
..Fibrosis (D005355) 16
..Genomic Instability (D042822) 5
..Gliosis (D005911) 1
..Granuloma (D006099) 17
..Granulomatosis, Orofacial (D051261)
..Growth Disorders (D006130) 191
..Hemolysis (D006461) 2
..Hemorrhage (D006470) 84
..Hyperammonemia (D022124) 3
..Hyperamylasemia (D034321)
..Hyperbilirubinemia (D006932) 13
..Hyperplasia (D006965) 4
..Hyperuricemia (D033461) 8
..Hypovolemia (D020896)
..Inflammation (D007249) 52
..Intraoperative Complications (D007431) 15
..Ischemia (D007511) 3
..Leukoaraiosis (D049292)
..Leukocytosis (D007964) 6
..Lithiasis (D020347)
..Malacoplakia (D008287) 1
..Menstruation Disturbances (D008599) 10
..Metaplasia (D008679) 4
..Muscle Weakness (D018908) 5
..Necrosis (D009336) 12
..Neointima (D058426)
..Neoplastic Processes (D009385) 18
..Nerve Degeneration (D009410) 7
..Ochronosis (D009794) 2
..Ossification, Heterotopic (D009999) 7
..Polydipsia (D059606) 1
..Postoperative Complications (D011183) 42
..Protein Aggregation, Pathological (D066263)
..Respiratory Aspiration (D053120) 1
..Retropneumoperitoneum (D012188)
..Sclerosis (D012598) 8
..Shock (D012769) 18
..Teratogenesis (D064793)
..Ulcer (D014456) 1
..Vascular Remodeling (D066253)
..Yang Deficiency (D016711)
..Yin Deficiency (D016710)
Human Disease MESH is developed by UMLS. Further data from MedGen, OMIM, CTD

Term ID:	7906
Name:	Nerve Degeneration
Definition:	Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.
Alternative IDs:
ParentIDs:	MESH:D010335
TreeNumbers:	C23.550.737
Synonyms:	Degeneration, Nerve \|Degeneration, Neuron \|Degenerations, Nerve \|Degenerations, Neuron \|Nerve Degenerations \|Neuron Degeneration \|Neuron Degenerations
Slim Mappings:	Pathology (process)
Reference:	MedGen: D009410 MeSH: D009410 OMIM: Genes:
Phenotypes
Disease Causing ClinVar Variants