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Disease Browser
Parent Node:
expandHyperlipoproteinemias (D006951)
Parent Node:
expandHypertriglyceridemia (D015228)
Parent Node:
expandLipid Metabolism, Inborn Errors (D008052)
..Starting node
..expandHyperlipoproteinemia Type IV (D006953)

       Child Nodes:



 Sister Nodes: 
..expand2,4-Dienoyl-CoA Reductase Deficiency (C565624)
..expandAcetyl-Coa Carboxylase Deficiency (C562678)
..expandAlpha-Methylacyl-CoA Racemase Deficiency (C565768)
..expandApolipoprotein E, Deficiency or Defect of (C566260)
..expandBarth Syndrome (D056889) Child2
..expandCarnitine palmitoyl transferase 1A deficiency (C535588)
..expandCarnitine Palmitoyltransferase II Deficiency, Infantile (C563462)
..expandCarnitine Palmitoyltransferase II Deficiency, Late-Onset (C563461)
..expandCarnitine-Acylcarnitine Translocase Deficiency (C562812)
..expandCholesteryl Ester Transfer Protein Deficiency (C564591)
..expandCytosolic acetoacetyl-CoA thiolase deficiency (C536005)
..expandDesmosterolosis (C566555)
..expandHydroxyacyl-CoA Dehydrogenase, Type 2, Deficiency (C536080)
..expandHyperlipidemia, Familial Combined (D006950) Child2
..expandHyperlipoproteinemia Type I (D008072) Child1
..expandHyperlipoproteinemia Type II (D006938) Child4
..expandHyperlipoproteinemia Type III (D006952)
..expandHyperlipoproteinemia Type IV (D006953)
..expandHyperlipoproteinemia Type V (D006954)
..expandHypolipoproteinemias (D007009) Child14
..expandLipase deficiency combined (C535904)
..expandLipidoses (D008064) Child71
..expandLipodystrophy, Congenital Generalized (D052497) Child3
..expandLong-chain acyl-CoA dehydrogenase deficiency (C535690)
..expandLp(A) Deficiency, Congenital (C563618)
..expandMedium chain acyl CoA dehydrogenase deficiency (C536038)
..expandMyopathy with Abnormal Lipid Metabolism (C562935)
..expandNeutral Lipid Storage Disease with Myopathy (C565192)
..expandPeroxisomal ACYL-COA oxidase deficiency (C536662)
..expandShort chain Acyl CoA dehydrogenase deficiency (C537596)
..expandSitosterolemia (C537345)
..expandSmith-Lemli-Opitz Syndrome (D019082) Child1
..expandTrifunctional Protein Deficiency With Myopathy And Neuropathy (C566945)
..expandTriglyceride storage disease with impaired long-chain fatty acid oxidation (C536560)
..expandTriglyceride Storage Disease, Type I (C566031)
..expandTriglyceride Storage Disease, Type II (C566030)
..expandVLCAD deficiency (C536353)
..expandXanthomatosis, Cerebrotendinous (D019294)
   

Human Disease MESH is developed by UMLS.
Further data from MedGen, OMIM, CTD
Term ID:5417
Name:Hyperlipoproteinemia Type IV
Definition:A hypertriglyceridemia disorder, often with autosomal dominant inheritance. It is characterized by the persistent elevations of plasma TRIGLYCERIDES, endogenously synthesized and contained predominantly in VERY-LOW-DENSITY LIPOPROTEINS (pre-beta lipoproteins). In contrast, the plasma CHOLESTEROL and PHOSPHOLIPIDS usually remain within normal limits.
Alternative IDs:OMIM:145750
ParentIDs:MESH:D006951|MESH:D008052|MESH:D015228
TreeNumbers:C16.320.565.398.487 |C18.452.584.500.500.644.490 |C18.452.584.500.500.851.500 |C18.452.648.398.487
Synonyms:Carbohydrate Inducible Hyperlipemia |Carbohydrate-Inducible Hyperlipemia |Carbohydrate Inducible Hyperlipemias |Carbohydrate-Inducible Hyperlipemias |Familial Hyperlipoproteinemia Type 4 |Familial Hypertriglyceridemia |Familial Type IV Hyperlipoproteinemia |Hyp
Slim Mappings:Genetic disease (inborn)|Metabolic disease
Reference: MedGen: D006953
MeSH: D006953
OMIM: 145750;

Genes: AF8T; APOA5; LIPI;
Phenotypes
1 HP:0000006Autosomal dominant inheritance
2 HP:0001039Atheroeruptive xanthoma
3 HP:0001952Glucose intolerance
4 HP:0002155Hypertriglyceridemia
5 HP:0003362Increased VLDL cholesterol concentration
6 HP:0004416Precocious atherosclerosis
Disease Causing ClinVar Variants