MSeqDR Mitochondrial Disease Portal


 
*:HP: HPO terms, ND: NAMDC terms.
  Most Studied  CPEO, Complex I Deficiency, COXPD1, Leigh, LHON, MELAS, MERRF, NARP, SANDO
Disease Browser
Parent Node:
expandanterior horn disease (MONDO:0003182)
Parent Node:
expandmotor neuron disease (MONDO:0020128)
Parent Node:
expandneurodegenerative disease (MONDO:0005559)
..Starting node
..expandamyotrophic lateral sclerosis ()

       Child Nodes:
........expandamyotrohpic lateral sclerosis type 22 ()
........expandamyotrophic lateral sclerosis type 21 ()
........expandamyotrophic lateral sclerosis type 23 ()
........expandamyotrophic lateral sclerosis type 3 ()
........expandamyotrophic lateral sclerosis type 7 ()
........expandamyotrophic lateral sclerosis type 8 ()
........expandamyotrophic lateral sclerosis type 9 ()
........expandamyotrophic lateral sclerosis with polyglucosan bodies ()
........expandamyotrophic lateral sclerosis, susceptibility to, 24 ()
........expandfamilial amyotrophic lateral sclerosis ()
........expandprogressive muscular atrophy ()
........expandsporadic amyotrophic lateral sclerosis ()



 Sister Nodes: 
..expandamyotrophic lateral sclerosis ()
..expandbrachial amyotrophic diplegia ()
..expandcerebellar degeneration ()
..expandcerebral degeneration ()
..expandcorticobasal degeneration disorder ()
..expanddemyelinating disease ()
..expandeye degenerative disease ()
..expandinherited neurodegenerative disorder ()
..expandMarchiafava-Bignami disease ()
..expandneuroaxonal dystrophy ()
..expandneurodegenerative disease with chorea ()
..expandneurodegenerative disease with dementia ()
..expandolivopontocerebellar atrophy ()
..expandoptic atrophy ()
..expandprimary progressive apraxia of speech ()
..expandsecondary Parkinson disease ()
..expandsenile degeneration of brain ()
..expandsynucleinopathy ()
..expandtauopathy ()
   

MONDO is developed by the Monarch Initiative. Human Disease MESH is developed by UMLS.
Further data from MedGen, OMIM,ClinVar, CTD
Term ID:4976
Name:amyotrophic lateral sclerosis
Definition:Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive muscular paralysis reflecting degeneration of motor neurons in the primary motor cortex, corticospinal tracts, brainstem and spinal cord.
Alternative IDs:
ParentIDs:
TreeNumbers:
Synonyms:ALS; Charcot disease; Lou Gehrig disease; Lou Gehrig's disease; motor neuron disease, bulbar
Slim Mappings:
Reference: MedGen:
MeSH:
OMIM:
MSeqDR LSDB:  
Genes:
Phenotypes
Disease Causing ClinVar Variants
MSeqDR Portal