MSeqDR Mitochondrial disease browser phenotype pathogenic gene and mutation portal

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Examples Gene: MT-ND1, POLG, Region: M:1-1000 Variant: m.8993T>G, 1:g.10042757T>C rs3888511 MSCV_0000006, ClinVar: RCV000000015, Disease: Leigh syndrome, Phenotype: Retinopathy

*:HP: HPO terms, ND: NAMDC terms.
Most Studied CPEO, Complex I Deficiency, COXPD1, Leigh, LHON, MELAS, MERRF, NARP, SANDO

Disease Browser
Parent Node: neoplasm of testis (MONDO:0021348)
Parent Node: sex cord-stromal tumor (MONDO:0006055)
..Starting node ..testicular sex cord-stromal neoplasm ()
Child Nodes:
........Sertoli-Leydig cell tumor ()
........testicular fibroma ()
........testicular granulosa cell tumor ()
........testicular Leydig cell tumor ()
........testicular thecoma ()
Sister Nodes:
..granulosa cell tumor ()
..Leydig cell tumor ()
..ovarian sex cord-stromal tumor ()
..Sertoli cell tumor ()
..testicular sex cord-stromal neoplasm ()
..thecoma ()
MONDO is developed by the Monarch Initiative. Human Disease MESH is developed by UMLS. Further data from MedGen, OMIM,ClinVar, CTD

Term ID:	3125
Name:	testicular sex cord-stromal neoplasm
Definition:	A benign or malignant tumor that arises from the testis. It is composed of granulosa cells, Leydig cells, Sertoli cells, and fibroblasts. Each of these cell types may constitute the only cellular component that is present in the tumor or it may be mixed with other cell types in various combinations. The prognosis can not always be predicted on histologic grounds alone. Approximately, ten percent of these tumors may metastasize. Representative examples include granulosa cell tumor, Leydig cell tumor, Sertoli cell tumor, and tumors of the thecoma-fibroma group.
Alternative IDs:
ParentIDs:
TreeNumbers:
Synonyms:	sex cord-stromal neoplasm; Sex cord-stromal neoplasm of testis; Sex cord-stromal neoplasm of the testis; Sex cord-stromal tumor of testis; sex cord-stromal tumor of testis; Sex cord-stromal tumor of the testis; testicular sex cord-stromal neoplasm; testicular Sex cord-stromal tumor; testis sex cord-
Slim Mappings:
Reference:	MedGen: MeSH: OMIM: MSeqDR : Genes:
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