Human Phenotype Ontology 
Grandparent Node:
expandAbnormal cardiac test (HP:0500015)help
Parent Node:
expandAbnormal cardiac biomarker test (HP:0500020)help
..Starting node
..expandIncreased circulating troponin I concentration (HP:0410173)help
Term ID: 410173
Name: Increased circulating troponin I concentration
Synonym: Increased troponin I level in blood
Definition: An increased concentration of tropnin I in the blood, which is a cardiac regulatory protein that controls the calcium mediated interaction between actin and myosin. Raised cardiac troponin concentrations are now accepted as the standard biochemical marker for the diagnosis of myocardial infarction.
Comments:
Reference: HP:0410173
Genes and Diseases:
 
       Child Nodes:

 Sister Nodes: 
..expandIncreased circulating troponin T concentration (HP:0410174) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0410173HP:0410173Increased circulating troponin I concentration0DSG2 CL E G H18293049OMIM:610193Arrhythmogenic right ventricular dysplasia, familial, 10358
HP:0410173HP:0410173Increased circulating troponin I concentration0SVIL CL E G H684011480OMIM:619040MYOFIBRILLAR MYOPATHY 10; MFM101


Genes (2) :DSG2 SVIL

Diseases (2) :OMIM:610193 OMIM:619040
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.