Human Phenotype Ontology 
Grandparent Node:
expandAbnormality of the coagulation cascade (HP:0003256)help
Parent Node:
expandAbnormality of prothrombin (HP:0012200)help
..Starting node
..expandReduced prothrombin antigen (HP:0040250)help
Term ID: 40250
Name: Reduced prothrombin antigen
Synonym:
Definition: Reduced prothrombin antigen as measured by ELISA assay. Prothrombin is a vitamin K-dependent coagulation factor that is proteolytically cleaved to form thrombin.
Comments:
Reference: HP:0040250
Genes and Diseases:
 
       Child Nodes:

 Sister Nodes: 
..expandobsolete Reduced prothrombin activity (HP:0012201) help
..expandProlonged prothrombin time (HP:0008151) help
..expandReduced prothrombin consumption (HP:0003337) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0040250HP:0040250Reduced prothrombin antigen0F2 CL E G H21473535ORPHA:325Congenital factor II deficiencyHP:0040281 - Very frequent44
HP:0040250HP:0040250Reduced prothrombin antigen0VKORC1 CL E G H7900123663OMIM:607473Vitamin K-dependent clotting factors, combined deficiency of, 225


Genes (2) :F2 VKORC1

Diseases (2) :ORPHA:325 OMIM:607473
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.