Human Phenotype Ontology

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Examples Gene: MT-ND1, POLG, Region: M:1-1000 Variant: m.8993T>G, 1:g.10042757T>C rs3888511 MSCV_0000006, ClinVar: RCV000000015, Disease: Leigh syndrome, Phenotype: Retinopathy

Grandparent Node:
Abnormality of neutrophil morphology (HP:0011992)

Parent Node:
Neutrophil inclusion bodies (HP:0008264)

..Starting node
..Leukocyte inclusion bodies (HP:0040235)

Term ID:

40235

Name:

Leukocyte inclusion bodies

Synonym:

Dohle-like leukocyte inclusion bodies; Inclusion bodies in leukocytes

Definition:

The presence of intraceullar inclusion bodies (aggregates of stainable substances, usually proteins) in leukocytes.

Comments:

Reference:

HP:0040235

Genes and Diseases:

Child Nodes:

Sister Nodes:

Input	HPO ID	HPO term	Distance	Gene	Gene id entrez	HGNC ID	DiseaseId	DiseaseName	Frequency	ClinVar variants
HPO disease - gene - phenotype typical associations:
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0040235	HP:0040235	Leukocyte inclusion bodies	0	MYH9 CL E G H	4627	7579	OMIM:155100	Macrothrombocytopenia and granulocyte inclusions with or without nephritis or sensorineural hearing loss	.	297

Genes (1) :MYH9

Diseases (1) :OMIM:155100

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.