Human Phenotype Ontology

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Examples Gene: MT-ND1, POLG, Region: M:1-1000 Variant: m.8993T>G, 1:g.10042757T>C rs3888511 MSCV_0000006, ClinVar: RCV000000015, Disease: Leigh syndrome, Phenotype: Retinopathy

..Starting node
..Viral encephalitis (HP:0033993)

Term ID:

33993

Name:

Viral encephalitis

Synonym:

Definition:

An inflammation of brain parenchyma due to infection with a virus. Viral encephalitis can occur as a rare complication of common infections (eg, herpes virus infections) or can occur as a characteristic presentation of rare viruses (eg, rabies virus infection). Encephalitis may be the only neurologic manifestation of infection, or may occur in association with meningitis, myelitis, radiculitis, or neuritis. Viral encephalitis is associated with neurological dysfunction.

Comments:

Reference:

HP:0033993

Genes and Diseases:

Child Nodes:

Sister Nodes:

Input	HPO ID	HPO term	Distance	Gene	Gene id entrez	HGNC ID	DiseaseId	DiseaseName	Frequency	ClinVar variants
HPO disease - gene - phenotype typical associations:
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0033993	HP:0033993	Viral encephalitis	0	CD27 CL E G H	939	11922	OMIM:615122	Lymphoproliferative syndrome 2		4
HP:0033993	HP:0033993	Viral encephalitis	0	CD40LG CL E G H	959	11935	OMIM:308230	Immunodeficiency, X-linked, with hyper-IgM		33
HP:0033993	HP:0033993	Viral encephalitis	0	DBR1 CL E G H	51163	15594	OMIM:619441	ENCEPHALITIS, ACUTE, INFECTION (VIRAL)-INDUCED, SUSCEPTIBILITY TO, 11; IIAE11
HP:0033993	HP:0033993	Viral encephalitis	0	HYOU1 CL E G H	10525	16931	OMIM:233600	Immunodeficiency 59 and hypoglycemia
HP:0033993	HP:0033993	Viral encephalitis	0	NCKAP1L CL E G H	3071	4862	OMIM:618982	IMMUNODEFICIENCY 72 WITH AUTOINFLAMMATION; IMD72
HP:0033993	HP:0033993	Viral encephalitis	0	SNORA31 CL E G H	677814	32621	OMIM:619396	ENCEPHALOPATHY, ACUTE, INFECTION-INDUCED (HERPES-SPECIFIC), SUSCEPTIBILITY TO, 10; IIAE10
HP:0033993	HP:0033993	Viral encephalitis	0	STAT1 CL E G H	6772	11362	OMIM:614892	Immunodeficiency 31A		89
HP:0033993	HP:0033993	Viral encephalitis	0	STAT1 CL E G H	6772	11362	OMIM:613796	Mycobacterial and viral infections, susceptibility to, autosomal recessive		89
HP:0033993	HP:0033993	Viral encephalitis	0	TBK1 CL E G H	29110	11584	OMIM:617900	Encephalopathy, acute, infection-induced (herpes-specific), susceptibility to, 8		20
HP:0033993	HP:0033993	Viral encephalitis	0	TICAM1 CL E G H	148022	18348	OMIM:614850	Encephalopathy, acute, infection-induced (herpes-specific), susceptibility to, 6		6
HP:0033993	HP:0033993	Viral encephalitis	0	TLR3 CL E G H	7098	11849	OMIM:613002	Encephalopathy, acute, infection-induced (herpes-specific), susceptibility to, 2		3
HP:0033993	HP:0033993	Viral encephalitis	0	UNC93B1 CL E G H	81622	13481	OMIM:610551	ENCEPHALOPATHY, ACUTE, INFECTION-INDUCED (HERPES-SPECIFIC), SUSCEPTIBILITY TO, 1; IIAE1		5
HP:0033993	HP:0033509	EBV encephalitis	1	CD27 CL E G H	939	11922	OMIM:615122	Lymphoproliferative syndrome 2		4
HP:0033993	HP:0034285	Enteroviral encephalitis	1	CD40LG CL E G H	959	11935	OMIM:308230	Immunodeficiency, X-linked, with hyper-IgM		33
HP:0033993	HP:0012302	Herpes simplex encephalitis	1	HYOU1 CL E G H	10525	16931	OMIM:233600	Immunodeficiency 59 and hypoglycemia
HP:0033993	HP:0012302	Herpes simplex encephalitis	1	NCKAP1L CL E G H	3071	4862	OMIM:618982	IMMUNODEFICIENCY 72 WITH AUTOINFLAMMATION; IMD72
HP:0033993	HP:0012302	Herpes simplex encephalitis	1	SNORA31 CL E G H	677814	32621	OMIM:619396	ENCEPHALOPATHY, ACUTE, INFECTION-INDUCED (HERPES-SPECIFIC), SUSCEPTIBILITY TO, 10; IIAE10
HP:0033993	HP:0012302	Herpes simplex encephalitis	1	STAT1 CL E G H	6772	11362	OMIM:614892	Immunodeficiency 31A	.	89
HP:0033993	HP:0012302	Herpes simplex encephalitis	1	STAT1 CL E G H	6772	11362	OMIM:613796	Mycobacterial and viral infections, susceptibility to, autosomal recessive	.	89
HP:0033993	HP:0012302	Herpes simplex encephalitis	1	TBK1 CL E G H	29110	11584	OMIM:617900	Encephalopathy, acute, infection-induced (herpes-specific), susceptibility to, 8	.	20
HP:0033993	HP:0012302	Herpes simplex encephalitis	1	TICAM1 CL E G H	148022	18348	OMIM:614850	Encephalopathy, acute, infection-induced (herpes-specific), susceptibility to, 6	.	6
HP:0033993	HP:0012302	Herpes simplex encephalitis	1	TLR3 CL E G H	7098	11849	OMIM:613002	Encephalopathy, acute, infection-induced (herpes-specific), susceptibility to, 2	.	3
HP:0033993	HP:0012302	Herpes simplex encephalitis	1	UNC93B1 CL E G H	81622	13481	OMIM:610551	ENCEPHALOPATHY, ACUTE, INFECTION-INDUCED (HERPES-SPECIFIC), SUSCEPTIBILITY TO, 1; IIAE1		5

Genes (11) :CD27 CD40LG DBR1 HYOU1 NCKAP1L SNORA31 STAT1 TBK1 TICAM1 TLR3 UNC93B1

Diseases (12) :OMIM:615122 OMIM:308230 OMIM:619441 OMIM:233600 OMIM:618982 OMIM:619396 OMIM:614892 OMIM:613796 OMIM:617900 OMIM:614850 OMIM:613002 OMIM:610551

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.

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