Human Phenotype Ontology 
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..expandPulmonary arterial hypertension with lack of acute response to NO challenge (HP:0033424)help
Term ID: 33424
Name: Pulmonary arterial hypertension with lack of acute response to NO challenge
Synonym:
Definition: A form of pulmonary arterial hypertension with lack of adequate hemodynamic response to NO challenge (adequate response is defined as a reduction of mean pulmonary artery pressure (mPAP) of at least 10 mmHg to reach an absolute value of mPAP 40 mmHg or less with an increased or unchanged cardiac output (CO) in response to inhaled nitric oxide at 10-20 ppm).
Comments:
Reference: HP:0033424
Genes and Diseases:
 
       Child Nodes:

 Sister Nodes: 
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0033424HP:0033424Pulmonary arterial hypertension with lack of acute response to NO challenge0KCNK3 CL E G H37776278OMIM:615344Pulmonary hypertension, primary, 47


Genes (1) :KCNK3

Diseases (1) :OMIM:615344
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.