Human Phenotype Ontology 
..Starting node
..expandDecreased nasal nitric oxide (HP:0033036)help
Term ID: 33036
Name: Decreased nasal nitric oxide
Synonym: Low nasal nitric oxide level
Definition: Reduced level of nasal nitric oxide (nNO). Current American Thoracic Society/European Respiratory Society (ATS/ERS) guidelines for nNO measurements recommend air aspiration via a nasal probe while the subject exhales through the mouth against resistance in order to maintain velum closure.
Comments:
Reference: HP:0033036
Genes and Diseases:
 
       Child Nodes:

 Sister Nodes: 
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0033036HP:0033036Decreased nasal nitric oxide0CCDC65 CL E G H8547829937OMIM:615504Ciliary dyskinesia, primary, 2723
HP:0033036HP:0033036Decreased nasal nitric oxide0CCNO CL E G H1030918576OMIM:615872Ciliary dyskinesia, primary, 2923
HP:0033036HP:0033036Decreased nasal nitric oxide0CFAP298 CL E G H566831301OMIM:615500Ciliary dyskinesia, primary, 26
HP:0033036HP:0033036Decreased nasal nitric oxide0CFAP52 CL E G H14684516053OMIM:619607HETEROTAXY, VISCERAL, 10, AUTOSOMAL, WITH MALE INFERTILITY; HTX10
HP:0033036HP:0033036Decreased nasal nitric oxide0DNAH11 CL E G H87012942OMIM:611884CILIARY DYSKINESIA, PRIMARY, 7; CILD7542
HP:0033036HP:0033036Decreased nasal nitric oxide0DNAH5 CL E G H17672950OMIM:608644CILIARY DYSKINESIA, PRIMARY, 3; CILD3527
HP:0033036HP:0033036Decreased nasal nitric oxide0DNAH9 CL E G H17702953OMIM:618300Ciliary dyskinesia, primary, 4018
HP:0033036HP:0033036Decreased nasal nitric oxide0DNAI2 CL E G H6444618744OMIM:612444CILIARY DYSKINESIA, PRIMARY, 9; CILD9104
HP:0033036HP:0033036Decreased nasal nitric oxide0DNAJB13 CL E G H37440730718OMIM:617091CILIARY DYSKINESIA, PRIMARY, 34; CILD342
HP:0033036HP:0033036Decreased nasal nitric oxide0DRC1 CL E G H9274924245OMIM:615294CILIARY DYSKINESIA, PRIMARY, 21; CILD2144
HP:0033036HP:0033036Decreased nasal nitric oxide0LRRC56 CL E G H11539925430OMIM:618254CILIARY DYSKINESIA, PRIMARY, 39; CILD39
HP:0033036HP:0033036Decreased nasal nitric oxide0MCIDAS CL E G H34564340050OMIM:618695CILIARY DYSKINESIA, PRIMARY, 42; CILD4213
HP:0033036HP:0033036Decreased nasal nitric oxide0ODAD3 CL E G H11594828303OMIM:616037Ciliary dyskinesia, primary, 30
HP:0033036HP:0033036Decreased nasal nitric oxide0RSPH3 CL E G H8386121054OMIM:616481Ciliary dyskinesia, primary, 325
HP:0033036HP:0033036Decreased nasal nitric oxide0RSPH4A CL E G H34589521558OMIM:612649Ciliary dyskinesia, primary, 1158
HP:0033036HP:0033036Decreased nasal nitric oxide0RSPH9 CL E G H22142121057OMIM:612650CILIARY DYSKINESIA, PRIMARY, 12; CILD1220
HP:0033036HP:0033036Decreased nasal nitric oxide0SPAG1 CL E G H667411212OMIM:615505Ciliary dyskinesia, primary, 2845
HP:0033036HP:0033036Decreased nasal nitric oxide0ZMYND10 CL E G H5136419412OMIM:615444Ciliary dyskinesia, primary, 2220


Genes (18) :CCDC65 CCNO CFAP298 CFAP52 DNAH11 DNAH5 DNAH9 DNAI2 DNAJB13 DRC1 LRRC56 MCIDAS ODAD3 RSPH3 RSPH4A RSPH9 SPAG1 ZMYND10

Diseases (18) :OMIM:615504 OMIM:615872 OMIM:615500 OMIM:619607 OMIM:611884 OMIM:608644 OMIM:618300 OMIM:612444 OMIM:617091 OMIM:615294 OMIM:618254 OMIM:618695 OMIM:616037 OMIM:616481 OMIM:612649 OMIM:612650 OMIM:615505 OMIM:615444
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.