Human Phenotype Ontology

Hello! Guest! Please Login or Register! Clinician Mode

Examples Gene: MT-ND1, POLG, Region: M:1-1000 Variant: m.8993T>G, 1:g.10042757T>C rs3888511 MSCV_0000006, ClinVar: RCV000000015, Disease: Leigh syndrome, Phenotype: Retinopathy

..Starting node
..Increased proportion of CD4-positive T cells (HP:0032219)

Term ID:

32219

Name:

Increased proportion of CD4-positive T cells

Synonym:

Elevated proportion of CD4-positive T cells; Increased proportion of CD4+ T cells; Increased proportion of CD4-positive, alpha-beta T cells

Definition:

An elevation in the proportion of CD4-positive T cells relative to the total number of T cells.

Comments:

Reference:

HP:0032219

Genes and Diseases:

Child Nodes:

Sister Nodes:

Input	HPO ID	HPO term	Distance	Gene	Gene id entrez	HGNC ID	DiseaseId	DiseaseName	ClinVar variants
HPO disease - gene - phenotype typical associations:
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0032219	HP:0032219	Increased proportion of CD4-positive T cells	0	OTULIN CL E G H	90268	25118	OMIM:617099	AUTOINFLAMMATION, PANNICULITIS, AND DERMATOSIS SYNDROME; AIPDS	3
HP:0032219	HP:0410391	Increased proportion of CD4-positive, alpha-beta memory T cells	1	CL E G H
HP:0032219	HP:0410375	Increased proportion of naive CD4 T cells	1	CL E G H
HP:0032219	HP:0025625	Elevated proportion of CD4+ effector memory T cells	1	CL E G H
HP:0032219	HP:0410394	Increased proportion of effector memory CD4-positive, alpha-beta T cells	2	CL E G H
HP:0032219	HP:0410393	Increased proportion of central memory CD4-positive, alpha-beta T cells	2	CL E G H

Genes (1) :OTULIN

Diseases (1) :OMIM:617099

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.