Human Phenotype Ontology

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Examples Gene: MT-ND1, POLG, Region: M:1-1000 Variant: m.8993T>G, 1:g.10042757T>C rs3888511 MSCV_0000006, ClinVar: RCV000000015, Disease: Leigh syndrome, Phenotype: Retinopathy

..Starting node
..Increased proportion of memory T cells (HP:0032184)

Term ID:

32184

Name:

Increased proportion of memory T cells

Synonym:

Increased proportion of CD4+CD29+ cells

Definition:

An abnormally elevated proportion of memory T cells compared to the total number of T cells in the blood.

Comments:

Reference:

HP:0032184

Genes and Diseases:

Child Nodes:

Sister Nodes:

Input	HPO ID	HPO term	Distance	Gene	Gene id entrez	HGNC ID	DiseaseId	DiseaseName	ClinVar variants
HPO disease - gene - phenotype typical associations:
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0032184	HP:0032184	Increased proportion of memory T cells	0	NCKAP1L CL E G H	3071	4862	OMIM:618982	IMMUNODEFICIENCY 72 WITH AUTOINFLAMMATION; IMD72
HP:0032184	HP:0032184	Increased proportion of memory T cells	0	SASH3 CL E G H	54440	15975	OMIM:301082		1
HP:0032184	HP:0032184	Increased proportion of memory T cells	0	TCF3 CL E G H	6929	11633	OMIM:619824	AGAMMAGLOBULINEMIA 8B, AUTOSOMAL RECESSIVE; AGM8B	2
HP:0032184	HP:0410391	Increased proportion of CD4-positive, alpha-beta memory T cells	1	CL E G H
HP:0032184	HP:0410392	Increased proportion of CD8-positive, alpha-beta memory T cells	1	SASH3 CL E G H	54440	15975	OMIM:301082		1
HP:0032184	HP:0410392	Increased proportion of CD8-positive, alpha-beta memory T cells	1	TCF3 CL E G H	6929	11633	OMIM:619824	AGAMMAGLOBULINEMIA 8B, AUTOSOMAL RECESSIVE; AGM8B	2
HP:0032184	HP:0410393	Increased proportion of central memory CD4-positive, alpha-beta T cells	2	CL E G H
HP:0032184	HP:0410396	Increased proportion of central memory CD8-positive, alpha-beta T cells	2	CL E G H
HP:0032184	HP:0410394	Increased proportion of effector memory CD4-positive, alpha-beta T cells	2	CL E G H
HP:0032184	HP:0500265	Increased proportion of CD8-positive, alpha-beta TEMRA T cells	2	SASH3 CL E G H	54440	15975	OMIM:301082		1
HP:0032184	HP:0410395	Increased proportion of effector memory CD8-positive, alpha-beta T cells	2	TCF3 CL E G H	6929	11633	OMIM:619824	AGAMMAGLOBULINEMIA 8B, AUTOSOMAL RECESSIVE; AGM8B	2

Genes (3) :NCKAP1L SASH3 TCF3

Diseases (3) :OMIM:618982 OMIM:301082 OMIM:619824

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.

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