Human Phenotype Ontology 
Grandparent Node:
expandAbnormality of the intrinsic pathway (HP:0010989)help
Parent Node:
expandAbnormal factor VIII activity (HP:0030976)help
..Starting node
..expandIncreased factor VIII activity (HP:0030977)help
Term ID: 30977
Name: Increased factor VIII activity
Synonym: Elevated factor VIII level
Definition: Increased activity of the coagulation factor VIII. Factor VIII (fVIII) is a cofactor in the intrinsic clotting cascade that is activated to fVIIIa in the presence of minute quantities of thrombin. fVIIIa acts as a receptor, for factors IXa and X.
Comments:
Reference: HP:0030977
Genes and Diseases:
 
       Child Nodes:

 Sister Nodes: 
..expandReduced factor VIII activity (HP:0003125) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0030977HP:0030977Increased factor VIII activity0F8 CL E G H21573546OMIM:301071THROMBOPHILIA, X-LINKED, DUE TO FACTOR VIII DEFECT; THPH13303


Genes (1) :F8

Diseases (1) :OMIM:301071
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.