Human Phenotype Ontology 
Grandparent Node:
expandAbnormal B cell subset distribution (HP:0025539)help
Parent Node:
expandAbnormal proportion of immature B cells (HP:0030376)help
..Starting node
..expandDecreased proportion of immature B cells (HP:0030378)help
Term ID: 30378
Name: Decreased proportion of immature B cells
Synonym: Decreased proportion of CD19+/CD21low B cells
Definition: A reduction in normal proportion of immature B cells (CD19+/ CD21low)in circulation relative to total number of B cells. Immature B cells (IgM+) are still in final stages of development within the bone marrow. Naive B cells are those which have left the bone marrow, before they bind to the antigen for which they're specific (IgM+/IgD+).
Comments:
Reference: HP:0030378
Genes and Diseases:
 
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 Sister Nodes: 
..expandIncreased proportion of immature B cells (HP:0030377) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0030378HP:0030378Decreased proportion of immature B cells0 CL E G H


Genes (0) :

Diseases (0) :
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.