Human Phenotype Ontology 
Grandparent Node:
expandAbnormal sperm morphology (HP:0012864)help
Parent Node:
expandAbnormal sperm head morphology (HP:0012865)help
..Starting node
..expandGlobozoospermia (HP:0012205)help
Term ID: 12205
Name: Globozoospermia
Synonym:
Definition: Any structural anomaly of the acrosome resulting in a round sperm head.
Comments:
Reference: HP:0012205
Genes and Diseases:
 
       Child Nodes:

 Sister Nodes: 
..expandAcephalic spermatozoa (HP:0012869) help
..expandDecreased acrosin in sperm head (HP:0031136) help
..expandMacrocephalic sperm head (HP:0025437) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0012205HP:0012205Globozoospermia0C2CD6 CL E G H15125414438OMIM:619805SPERMATOGENIC FAILURE 68; SPGF681
HP:0012205HP:0012205Globozoospermia0CCDC62 CL E G H8466030723OMIM:619803SPERMATOGENIC FAILURE 67; SPGF67
HP:0012205HP:0012205Globozoospermia0DPY19L2 CL E G H28341719414OMIM:613958Spermatogenic failure 9.17
HP:0012205HP:0012205Globozoospermia0GGN CL E G H19972018869OMIM:619826SPERMATOGENIC FAILURE 69; SPGF69
HP:0012205HP:0012205Globozoospermia0NANOS1 CL E G H34071923044ORPHA:399808Male infertility with teratozoospermia due to single gene mutationHP:0040281 - Very frequent4
HP:0012205HP:0012205Globozoospermia0SPATA16 CL E G H8389329935OMIM:102530SPERMATOGENIC FAILURE 6; SPGF631
HP:0012205HP:0012205Globozoospermia0ZPBP CL E G H1105515662OMIM:619799SPERMATOGENIC FAILURE 66; SPGF66


Genes (7) :C2CD6 CCDC62 DPY19L2 GGN NANOS1 SPATA16 ZPBP

Diseases (7) :OMIM:619805 OMIM:619803 OMIM:613958 OMIM:619826 ORPHA:399808 OMIM:102530 OMIM:619799
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.