Human Phenotype Ontology

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Examples Gene: MT-ND1, POLG, Region: M:1-1000 Variant: m.8993T>G, 1:g.10042757T>C rs3888511 MSCV_0000006, ClinVar: RCV000000015, Disease: Leigh syndrome, Phenotype: Retinopathy

Grandparent Node:
Abnormality of circulating cortisol level (HP:0011731)

Grandparent Node:
Adrenal overactivity (HP:0002717)

Parent Node:
Increased circulating cortisol level (HP:0003118)

..Starting node
..Secondary hypercortisolism (HP:0011744)

Term ID:

11744

Name:

Secondary hypercortisolism

Synonym:

ACTH-dependent hypercortisolemia

Definition:

Hypercortisolemia associated with a overproduction of ACTH (often from a tumor), leading secondarily to overproduction of cortisol.

Comments:

Reference:

HP:0011744

Genes and Diseases:

Child Nodes:

Sister Nodes:

Elevated serum 11-deoxycortisol (HP:0025436)

Primary hypercortisolism (HP:0001579)

Input	HPO ID	HPO term	Distance	Gene
HPO disease - gene - phenotype typical associations:
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0011744	HP:0011744	Secondary hypercortisolism	0	CL E G H

Genes (0) :

Diseases (0) :

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.