Human Phenotype Ontology 
Grandparent Node:
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Abnormal larynx morphology (HP:0025423)help
Parent Node:
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Abnormal epiglottis morphology (HP:0005483)help
..Starting node
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Bifid epiglottis (HP:0010564)help
Term ID: 10564
Name: Bifid epiglottis
Synonym:
Definition: A midline anterior-posterior cleft of the epiglottis that involves at least two-thirds of the epiglottic leaf. It is a useful feature for clinical diagnosis because it appears to be very rare in syndromes other than Pallister-Hall-Syndrome and is also rare as an isolated malformation.
Comments:
Reference: HP:0010564
Genes and Diseases:
 
       Child Nodes:

 Sister Nodes: 
..expandAplasia/Hypoplasia of the Epiglottis (HP:0010565) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0010564HP:0010564Bifid epiglottis0DYNC2H1 CL E G H796592962ORPHA:93271Short rib-polydactyly syndrome, Verma-Naumoff typeHP:0040283 - Occasional304
HP:0010564HP:0010564Bifid epiglottis0DYNC2I1 CL E G H5511221862ORPHA:93271Short rib-polydactyly syndrome, Verma-Naumoff typeHP:0040283 - Occasional
HP:0010564HP:0010564Bifid epiglottis0DYNC2I2 CL E G H8989128296ORPHA:93271Short rib-polydactyly syndrome, Verma-Naumoff typeHP:0040283 - Occasional
HP:0010564HP:0010564Bifid epiglottis0FOXE1 CL E G H23043806OMIM:241850Hypothyroidism, athyroidal, with spiky hair and cleft palate.9
HP:0010564HP:0010564Bifid epiglottis0GLI3 CL E G H27374319OMIM:146510Pallister-Hall syndrome270
HP:0010564HP:0010564Bifid epiglottis0GLI3 CL E G H27374319ORPHA:672Pallister-Hall syndromeHP:0040283 - Occasional270
HP:0010564HP:0010564Bifid epiglottis0IFT80 CL E G H5756029262ORPHA:93271Short rib-polydactyly syndrome, Verma-Naumoff typeHP:0040283 - Occasional65
HP:0010564HP:0010564Bifid epiglottis0WDR35 CL E G H5753929250ORPHA:93271Short rib-polydactyly syndrome, Verma-Naumoff typeHP:0040283 - Occasional136


Genes (7) :DYNC2H1 DYNC2I1 DYNC2I2 FOXE1 GLI3 IFT80 WDR35

Diseases (4) :ORPHA:93271 OMIM:241850 OMIM:146510 ORPHA:672
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.