Human Phenotype Ontology 
Grandparent Node:
expandobsolete Cleft secondary palate (HP:0410004)help
Parent Node:
expandCleft hard palate (HP:0410005)help
..Starting node
..expandCleft of alveolar ridge of maxilla (HP:0010289)help
Term ID: 10289
Name: Cleft of alveolar ridge of maxilla
Synonym: Alveolar ridge cleft; Cleft of alveolar process; Cleft of gum ridge; Notch of alveolar process; Notch of alveolar ridge; Notch of gum ridge
Definition: A gap (cleft) affecting one of the alveolar ridges, which are the protuberances in the mouth that contain the sockets (alveoli) of the teeth. An alveolar cleft can affect all structures of the alveolar ridge, including the gingiva, other mucosa, periosteum, alveolar bone, and teeth.
Comments:
Reference: HP:0010289
Genes and Diseases:
 
       Child Nodes:
........expandCleft lower alveolar ridge (HP:0009094) help
........expandUnilateral alveolar cleft of maxilla (HP:0410033) help
........expandBilateral alveolar cleft of maxilla (HP:0410034) help

 Sister Nodes: 
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0010289HP:0010289Cleft of alveolar ridge of maxilla0EIF4A3 CL E G H977518683OMIM:268305Robin sequence with cleft mandible and limb anomalies4
HP:0010289HP:0010289Cleft of alveolar ridge of maxilla0NEK1 CL E G H47507744ORPHA:2751Orofaciodigital syndrome type 2101
HP:0010289HP:0010289Cleft of alveolar ridge of maxilla0NUAK2 CL E G H8178829558OMIM:619452ANENCEPHALY 2; ANPH2
HP:0010289HP:0410034Bilateral alveolar cleft of maxilla1 CL E G H
HP:0010289HP:0009094Cleft lower alveolar ridge1EIF4A3 CL E G H977518683OMIM:268305Robin sequence with cleft mandible and limb anomalies.4
HP:0010289HP:0410033Unilateral alveolar cleft of maxilla1NEK1 CL E G H47507744ORPHA:2751Orofaciodigital syndrome type 2HP:0040283 - Occasional101


Genes (3) :EIF4A3 NEK1 NUAK2

Diseases (3) :OMIM:268305 ORPHA:2751 OMIM:619452
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.