Human Phenotype Ontology 
Grandparent Node:
expandVertebral arch anomaly (HP:0008438)help
Parent Node:
expandNarrow vertebral interpedicular distance (HP:0008450)help
..Starting node
..expandCaudal interpedicular narrowing (HP:0008457)help
Term ID: 8457
Name: Caudal interpedicular narrowing
Synonym: Caudal narrowing of interpedicular distances
Definition: Narrowing (becoming gradually narrower) of the distance between vertebral pedicles that gets progressively more severe towards to caudal (lower) end of the vertebral column. Note that normally, the interpedicular distances get progressively wider as one proceeds down the spine.
Comments:
Reference: HP:0008457
Genes and Diseases:
 
       Child Nodes:
........expandLumbar interpedicular narrowing (HP:0008486) help

 Sister Nodes: 
..expandLower thoracic interpediculate narrowness (HP:0008470) help
..expandThoracolumbar interpediculate narrowness (HP:0008484) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0008457HP:0008457Caudal interpedicular narrowing0KIF22 CL E G H38356391OMIM:603546Spondyloepimetaphyseal dysplasia with joint laxity, type 2.14
HP:0008457HP:0008457Caudal interpedicular narrowing0PDE4D CL E G H51448783ORPHA:439822PDE4D haploinsufficiency syndromeHP:0040283 - Occasional113
HP:0008457HP:0008457Caudal interpedicular narrowing0TONSL CL E G H47967801OMIM:271510Spondyloepimetaphyseal dysplasia, Sponastrime type
HP:0008457HP:0008486Lumbar interpedicular narrowing1TONSL CL E G H47967801OMIM:271510Spondyloepimetaphyseal dysplasia, Sponastrime type.


Genes (3) :KIF22 PDE4D TONSL

Diseases (3) :OMIM:603546 ORPHA:439822 OMIM:271510
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.