Human Phenotype Ontology 
Grandparent Node:
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Abnormal nervous system physiology (HP:0012638)help
Parent Node:
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Abnormality of movement (HP:0100022)help
..Starting node
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Frontal release signs (HP:0000743)help
Term ID: 743
Name: Frontal release signs
Synonym: Frontal release reflexes
Definition: Primitive reflexes traditionally held to be a sign of disorders that affect the frontal lobes.
Comments:
Reference: HP:0000743
Genes and Diseases:
 
       Child Nodes:

 Sister Nodes: 
..expandAbnormal head movements (HP:0002457) help
..expandAbnormal posturing (HP:0002533) help
..expandAbnormal reflex (HP:0031826) help
..expandAstasia (HP:0020037) help
..expandAsterixis (HP:0012164) help
..expandBimanual synkinesia (HP:0001335) help
..expandCerebral palsy (HP:0100021) help
..expandDiminished movement (HP:0002374) help
..expandDyskinesia (HP:0100660) help
..expandDystonia (HP:0001332) help
..expandGait disturbance (HP:0001288) help
..expandHyperactivity (HP:0000752) help
..expandHyperkinetic movements (HP:0002487) help
..expandInvoluntary movements (HP:0004305) help
..expandMuscle fibrillation (HP:0010546) help
..expandMyokymia (HP:0002411) help
..expandPostural instability (HP:0002172) help
..expandPrimitive reflex (HP:0002476) help
..expandStooped posture (HP:0025403) help
InputHPO IDHPO termDistanceGeneGene id entrezDiseaseIdDiseaseNameDiseaseMIMConceptIDSourceTypical associationHGMD variantsClinVar variantsHGNC IDGeneMIM
 
HPO disease - gene - phenotype typical associations:
HP:0000743HP:0000743Frontal release signs0CHMP2B CL E G H25978600795Frontotemporal Dementia, Chromosome 3-Linked600795C1833296OMIM113024537609512
HP:0000743HP:0000743Frontal release signs0CHMP2B CL E G H25978600795Frontotemporal Dementia, Chromosome 3-Linked600795C1833296OMIM111024537609512
HP:0000743HP:0000743Frontal release signs0TBP CL E G H6908607136Spinocerebellar ataxia 17607136C1846707OMIM110611588600075
HP:0000743HP:0000743Frontal release signs0TBP CL E G H6908607136Spinocerebellar ataxia 17607136C1846707OMIM110211588600075
HP:0000743HP:0000743Frontal release signs0WDR45 CL E G H11152329284ORPHA146428912300526
HP:0000743HP:0000743Frontal release signs0WDR45 CL E G H11152329284ORPHA143128912300526
HP:0000743HP:0000743Frontal release signs0WDR45 CL E G H11152300894Neurodegeneration with brain iron accumulation 5300894C3550973OMIM146428912300526
HP:0000743HP:0000743Frontal release signs0WDR45 CL E G H11152300894Neurodegeneration with brain iron accumulation 5300894C3550973OMIM143128912300526
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0000743HP:0000743Frontal release signs0MAPT CL E G H4137601104Progressive supranuclear ophthalmoplegia601104C0038868OMIM04886893157140
HP:0000743HP:0000743Frontal release signs0MAPT CL E G H4137601104Progressive supranuclear ophthalmoplegia601104C0038868OMIM04656893157140


Genes (4) :CHMP2B MAPT TBP WDR45

Diseases (5) :600795 601104 607136 329284 300894
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is August 2021 release.