Human Phenotype Ontology 
Grandparent Node:
expandAbnormal peripheral nervous system morphology (HP:0000759)help
Parent Node:
expandPeripheral neuropathy (HP:0009830)help
..Starting node
..expandProgressive peripheral neuropathy (HP:0007133)help
Term ID: 7133
Name: Progressive peripheral neuropathy
Synonym: Progressive polyneuropathy
Definition:
Comments:
Reference: HP:0007133
Genes and Diseases:
 
       Child Nodes:

 Sister Nodes: 
..expandAcute episodes of neuropathic symptoms (HP:0003489) help
..expandChronic sensorineural polyneuropathy (HP:0001301) help
..expandCongenital peripheral neuropathy (HP:0006903) help
..expandDemyelinating peripheral neuropathy (HP:0007108) help
..expandEntrapment neuropathy (HP:0012181) help
..expandEpisodic peripheral neuropathy (HP:0006949) help
..expandMixed demyelinating and axonal polyneuropathy (HP:0007327) help
..expandMononeuropathy (HP:0009831) help
..expandMotor polyneuropathy (HP:0007178) help
..expandPeripheral axonal neuropathy (HP:0003477) help
..expandPolyneuropathy (HP:0001271) help
..expandSensorimotor neuropathy (HP:0007141) help
..expandSensorimotor polyneuropathy affecting arms more than legs (HP:0006865) help
..expandSensory neuropathy (HP:0000763) help
..expandSomatic sensory dysfunction (HP:0003474) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0007133HP:0007133Progressive peripheral neuropathy0ABCA1 CL E G H1929ORPHA:31150Tangier diseaseHP:0040282 - Frequent191
HP:0007133HP:0007133Progressive peripheral neuropathy0ARSA CL E G H410713OMIM:250100Metachromatic leukodystrophy.253
HP:0007133HP:0007133Progressive peripheral neuropathy0ARSA CL E G H410713ORPHA:309271Metachromatic leukodystrophy, adult formHP:0040283 - Occasional253
HP:0007133HP:0007133Progressive peripheral neuropathy0ARSA CL E G H410713ORPHA:309263Metachromatic leukodystrophy, juvenile formHP:0040283 - Occasional253
HP:0007133HP:0007133Progressive peripheral neuropathy0ARSA CL E G H410713ORPHA:309256Metachromatic leukodystrophy, late infantile formHP:0040282 - Frequent253
HP:0007133HP:0007133Progressive peripheral neuropathy0COA8 CL E G H8433420492ORPHA:436271Non-progressive predominantly posterior cavitating leukoencephalopathy with peripheral neuropathyHP:0040281 - Very frequent
HP:0007133HP:0007133Progressive peripheral neuropathy0LYST CL E G H11301968OMIM:214500Chediak-Higashi syndrome239
HP:0007133HP:0007133Progressive peripheral neuropathy0PSAP CL E G H56609498ORPHA:309271Metachromatic leukodystrophy, adult formHP:0040283 - Occasional81
HP:0007133HP:0007133Progressive peripheral neuropathy0PSAP CL E G H56609498ORPHA:309263Metachromatic leukodystrophy, juvenile formHP:0040283 - Occasional81
HP:0007133HP:0007133Progressive peripheral neuropathy0PSAP CL E G H56609498ORPHA:309256Metachromatic leukodystrophy, late infantile formHP:0040282 - Frequent81


Genes (5) :ABCA1 ARSA COA8 LYST PSAP

Diseases (7) :ORPHA:31150 OMIM:250100 ORPHA:309271 ORPHA:309263 ORPHA:309256 ORPHA:436271 OMIM:214500
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.