Human Phenotype Ontology

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Hello! Guest! Please Login or Register! Clinician Mode

Examples Gene: MT-ND1, POLG, Region: M:1-1000 Variant: m.8993T>G, 1:g.10042757T>C rs3888511 MSCV_0000006, ClinVar: RCV000000015, Disease: Leigh syndrome, Phenotype: Retinopathy

Grandparent Node:
Abnormal liver morphology (HP:0410042)

Grandparent Node:
Increased inflammatory response (HP:0012649)

Parent Node:
Hepatitis (HP:0012115)

..Starting node
..Viral hepatitis (HP:0006562)

Term ID:

6562

Name:

Viral hepatitis

Synonym:

Definition:

Inflammation of the liver due to infection with a virus.

Comments:

Reference:

HP:0006562

Genes and Diseases:

Child Nodes:

........

Enteroviral hepatitis (HP:0001412)

........

Subacute progressive viral hepatitis (HP:0006572)

Sister Nodes:

Acute hepatitis (HP:0200119)

Atypical or prolonged hepatitis (HP:0200122)

Chronic hepatitis (HP:0200123)

Fulminant hepatitis (HP:0004787)

Giant cell hepatitis (HP:0200084)

Input	HPO ID	HPO term	Distance	Gene	Gene id entrez	HGNC ID	DiseaseId	DiseaseName	Frequency	ClinVar variants
HPO disease - gene - phenotype typical associations:
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0006562	HP:0006562	Viral hepatitis	0	APC CL E G H	324	583	OMIM:114550	Hepatocellular carcinoma		3179
HP:0006562	HP:0006562	Viral hepatitis	0	AXIN1 CL E G H	8312	903	OMIM:114550	Hepatocellular carcinoma		3
HP:0006562	HP:0006562	Viral hepatitis	0	BTK CL E G H	695	1133	OMIM:300755	Agammaglobulinemia, X-linked		109
HP:0006562	HP:0006562	Viral hepatitis	0	BTK CL E G H	695	1133	OMIM:307200	Isolated growth hormone deficiency, type III, with agammaglobulinemia		109
HP:0006562	HP:0006562	Viral hepatitis	0	CASP8 CL E G H	841	1509	OMIM:114550	Hepatocellular carcinoma		37
HP:0006562	HP:0006562	Viral hepatitis	0	CIITA CL E G H	4261	7067	OMIM:209920	Bare lymphocyte syndrome, type II	.	118
HP:0006562	HP:0006562	Viral hepatitis	0	CTNNB1 CL E G H	1499	2514	OMIM:114550	Hepatocellular carcinoma		88
HP:0006562	HP:0006562	Viral hepatitis	0	IGF2R CL E G H	3482	5467	OMIM:114550	Hepatocellular carcinoma		4
HP:0006562	HP:0006562	Viral hepatitis	0	IGHG2 CL E G H	3501	5526	ORPHA:183675	Recurrent infections associated with rare immunoglobulin isotypes deficiency		1
HP:0006562	HP:0006562	Viral hepatitis	0	IGKC CL E G H	3514	5716	ORPHA:183675	Recurrent infections associated with rare immunoglobulin isotypes deficiency		5
HP:0006562	HP:0006562	Viral hepatitis	0	MET CL E G H	4233	7029	OMIM:114550	Hepatocellular carcinoma		375
HP:0006562	HP:0006562	Viral hepatitis	0	PDGFRL CL E G H	5157	8805	OMIM:114550	Hepatocellular carcinoma		2
HP:0006562	HP:0006562	Viral hepatitis	0	PIK3CA CL E G H	5290	8975	OMIM:114550	Hepatocellular carcinoma		162
HP:0006562	HP:0006562	Viral hepatitis	0	RFX5 CL E G H	5993	9986	OMIM:209920	Bare lymphocyte syndrome, type II	.	38
HP:0006562	HP:0006562	Viral hepatitis	0	RFXANK CL E G H	8625	9987	OMIM:209920	Bare lymphocyte syndrome, type II	.	26
HP:0006562	HP:0006562	Viral hepatitis	0	RFXAP CL E G H	5994	9988	OMIM:209920	Bare lymphocyte syndrome, type II	.	34
HP:0006562	HP:0006562	Viral hepatitis	0	TP53 CL E G H	7157	11998	OMIM:114550	Hepatocellular carcinoma		911
HP:0006562	HP:0006572	Subacute progressive viral hepatitis	1	APC CL E G H	324	583	OMIM:114550	Hepatocellular carcinoma	.	3179
HP:0006562	HP:0006572	Subacute progressive viral hepatitis	1	AXIN1 CL E G H	8312	903	OMIM:114550	Hepatocellular carcinoma	.	3
HP:0006562	HP:0001412	Enteroviral hepatitis	1	BTK CL E G H	695	1133	OMIM:300755	Agammaglobulinemia, X-linked	.	109
HP:0006562	HP:0001412	Enteroviral hepatitis	1	BTK CL E G H	695	1133	OMIM:307200	Isolated growth hormone deficiency, type III, with agammaglobulinemia	.	109
HP:0006562	HP:0006572	Subacute progressive viral hepatitis	1	CASP8 CL E G H	841	1509	OMIM:114550	Hepatocellular carcinoma	.	37
HP:0006562	HP:0006572	Subacute progressive viral hepatitis	1	CTNNB1 CL E G H	1499	2514	OMIM:114550	Hepatocellular carcinoma	.	88
HP:0006562	HP:0006572	Subacute progressive viral hepatitis	1	IGF2R CL E G H	3482	5467	OMIM:114550	Hepatocellular carcinoma	.	4
HP:0006562	HP:0006572	Subacute progressive viral hepatitis	1	MET CL E G H	4233	7029	OMIM:114550	Hepatocellular carcinoma	.	375
HP:0006562	HP:0006572	Subacute progressive viral hepatitis	1	PDGFRL CL E G H	5157	8805	OMIM:114550	Hepatocellular carcinoma	.	2
HP:0006562	HP:0006572	Subacute progressive viral hepatitis	1	PIK3CA CL E G H	5290	8975	OMIM:114550	Hepatocellular carcinoma	.	162
HP:0006562	HP:0006572	Subacute progressive viral hepatitis	1	TP53 CL E G H	7157	11998	OMIM:114550	Hepatocellular carcinoma	.	911

Genes (16) :APC AXIN1 BTK CASP8 CIITA CTNNB1 IGF2R IGHG2 IGKC MET PDGFRL PIK3CA RFX5 RFXANK RFXAP TP53

Diseases (5) :OMIM:114550 OMIM:300755 OMIM:307200 OMIM:209920 ORPHA:183675

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.

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