Human Phenotype Ontology 
Grandparent Node:
expandAbnormality of immune system physiology (HP:0010978)help
Parent Node:
expandImpaired antigen-specific response (HP:0031404)help
..Starting node
..expandImpaired pathogen-specific CD8 cytoxicity (HP:0031403)help
Term ID: 31403
Name: Impaired pathogen-specific CD8 cytoxicity
Synonym: Pathogen-specific CD8 cytoxicity defect
Definition: Impaired response of CD8 T cells to pathogens. CD8 T cells direct the killing of a target cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.
Comments:
Reference: HP:0031403
Genes and Diseases:
 
       Child Nodes:

 Sister Nodes: 
..expandDecreased circulating level of specific antibody (HP:0012475) help
..expandReduced antigen-specific T cell proliferation (HP:0031402) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0031403HP:0031403Impaired pathogen-specific CD8 cytoxicity0 CL E G H


Genes (0) :

Diseases (0) :
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.