Human Phenotype Ontology 
Grandparent Node:
expandPhenotypic abnormality (HP:0000118)help
Parent Node:
expandAbnormality of the immune system (HP:0002715)help
..Starting node
..expandAbnormality of immune system physiology (HP:0010978)help
Term ID: 10978
Name: Abnormality of immune system physiology
Synonym:
Definition: A functional abnormality of the immune system.
Comments:
Reference: HP:0010978
Genes and Diseases:There are 910 terms for your input, too many to show detail here. Please try its child terms.
 
       Child Nodes:
........expandRecurrent infections (HP:0002719) help
................... HP:0000010 Recurrent urinary tract infections
................... HP:0000403 Recurrent otitis media
................... HP:0002205 Recurrent respiratory infections
................... HP:0002718 Recurrent bacterial infections
................... HP:0002722 Recurrent abscess formation
................... HP:0002841 Recurrent fungal infections
................... HP:0004429 Recurrent viral infections
................... HP:0004798 Recurrent infection of the gastrointestinal tract
................... HP:0005386 Recurrent protozoan infections
................... HP:0005390 Recurrent opportunistic infections
................... HP:0005437 Recurrent infections in infancy and early childhood
................... HP:0008866 Failure to thrive secondary to recurrent infections
................... HP:0030885 Recurrent parasitic infections
................... HP:0040268 Recurrent infections of the middle ear
................... HP:0410018 Recurrent ear infections
........expandImmunodeficiency (HP:0002721) help
................... HP:0005363 Humoral immunodeficiency
................... HP:0005374 Cellular immunodeficiency
................... HP:0005387 Combined immunodeficiency
........expandImmune dysregulation (HP:0002958) help
........expandAutoimmunity (HP:0002960) help
................... HP:0000872 Hashimoto thyroiditis
................... HP:0001890 Autoimmune hemolytic anemia
................... HP:0001904 Autoimmune neutropenia
................... HP:0001973 Autoimmune thrombocytopenia
................... HP:0002725 Systemic lupus erythematosus
................... HP:0030057 Autoimmune antibody positivity
........expandAbnormality of humoral immunity (HP:0005368) help
................... HP:0005339 Abnormality of complement system
................... HP:0010701 Abnormal immunoglobulin level
................... HP:0012224 Circulating immune complexes
................... HP:0012475 Specific antibody deficiency
................... HP:0100778 Cryoglobulinemia
........expandAbnormality of immune serum protein physiology (HP:0011111) help
................... HP:0011112 Abnormality of serum cytokine level
................... HP:0011113 Abnormality of cytokine secretion
................... HP:0031406 Abnormal cytokine signaling
........expandAbnormal inflammatory response (HP:0012647) help
................... HP:0012648 Decreased inflammatory response
................... HP:0012649 Increased inflammatory response
........expandChronic infection (HP:0031035) help
........expandAbnormal lymphocyte surface marker expression (HP:0031383) help
................... HP:0001983 Reduced lymphocyte surface expression of CD43
................... HP:0031384 Reduced T cell CD40 expression
........expandAbnormal MHC II surface expression (HP:0031389) help
................... HP:0031390 Reduced MHC II surface expression
................... HP:0031391 Elevated MHC II surface expression
........expandImpaired antigen-specific response (HP:0031404) help
................... HP:0012475 Specific antibody deficiency
................... HP:0031402 Reduced antigen-specific T cell proliferation
................... HP:0031403 Impaired pathogen-specific CD8 cytoxicity
........expandAbnormal lymphocyte physiology (HP:0031409) help
................... HP:0011840 Abnormality of T cell physiology
................... HP:0012177 Abnormal natural killer cell physiology
................... HP:0030886 Abnormal lymphocyte apoptosis
................... HP:0031378 Abnormal lymphocyte proliferation
........expandOpportunistic infection (HP:0031690) help
................... HP:0005390 Recurrent opportunistic infections
................... HP:0031691 Severe viral infection
................... HP:0031696 Disseminated viral infection
................... HP:0031698 Disseminated Bacillus Calmette-Guerin infection
................... HP:0031699 Disseminated cryptosporidium infection
................... HP:0031700 Invasive parasitic infection
........expandImmunologic hypersensitivity (HP:0100326) help
................... HP:0002099 Asthma
................... HP:0002608 Celiac disease
................... HP:0012393 Allergy
................... HP:0100845 Anaphylactic shock
........expandSepsis (HP:0100806) help
................... HP:0040187 Neonatal sepsis

 Sister Nodes: 
..expandAbnormal cellular immune system morphology (HP:0010987) help
..expandAbnormality of the lymphatic system (HP:0100763) help


Genes (0) :

Diseases (0) :
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.