Human Phenotype Ontology 
Grandparent Node:
expandAbnormality of T cell physiology (HP:0011840)help
Parent Node:
expandAbnormal T cell activation (HP:0410035)help
..Starting node
..expandAbnormal CD25 upregulation upon TCR activation (HP:0031269)help
Term ID: 31269
Name: Abnormal CD25 upregulation upon TCR activation
Synonym:
Definition: Any abnormality in the upregulation of CD25 on T cells after activation via the T cell receptor (TCR). CD25 is the alpha chain of the IL2 receptor. Ligation of the T cell antigen receptor leads to the induction of CD25 expression.
Comments:
Reference: HP:0031269
Genes and Diseases:
 
       Child Nodes:
........expandDecreased CD25 upregulation upon TCR activation (HP:0031270) help

 Sister Nodes: 
..expandAbnormal CD69 upregulation upon TCR activation (HP:0031267) help
..expandDecreased T cell activation (HP:0005419) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0031269HP:0031269Abnormal CD25 upregulation upon TCR activation0 CL E G H
HP:0031269HP:0031270Decreased CD25 upregulation upon TCR activation1 CL E G H


Genes (0) :

Diseases (0) :
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.