Human Phenotype Ontology 
Grandparent Node:
expandAbnormal lung morphology (HP:0002088)help
Parent Node:
expandPulmonary interstitial high-resolution computed tomography abnormality (HP:0025389)help
Parent Node:
expandPulmonary opacity (HP:0031457)help
..Starting node
..expandGround-glass opacification (HP:0025179)help
Term ID: 25179
Name: Ground-glass opacification
Synonym: GGO; Ground glass opacities; Ground-glass opacification on pulmonary HRCT
Definition: On chest radiographs, ground-glass opacity appears as an area of hazy increased lung opacity, usually extensive, within whichnmargins of pulmonary vessels may be indistinct. On CT scans, it appears as hazy increased opacity of lung, with preservation of bronchial and vascular margins. It is caused by partial filling of airspaces, interstitial thickening (due to fluid, cells, and/or fibrosis), partial collapse of alveoli, increased capillary blood volume, or a combination of these, the common factor being the partial displacement of air. Ground-glass opacity is less opaque than consolidation, in which bronchovascular margins are obscured.
Comments:
Reference: HP:0025179
Genes and Diseases: SELECT DISTINCT 'HP:0025179' AS Input, t2.acc as HPO_ID, t2.name as HPO_term, g.Distance, t1.Entrez_gene AS Gene, t1.Entrez_gene_id AS Gene_id_entrez, t1.HGNC_ID, t1.DiseaseId, t1.DiseaseName, t1.Frequency, t1.Onset #, t1.ConceptID, Source, t1.Typical_association , h.Variants AS HGMD_variants, c.variants AS ClinVar_variants FROM hpo202212.graph_path AS g, hpo202212.term AS t, hpo202212.term AS t2 LEFT JOIN hpo202212.hpo_phenotype_to_genes as t1 ON (t1.HPO = t2.acc) LEFT JOIN gb_exome.clinvar_variation_latest_sum AS c ON ( c.Gene = t1.Entrez_Gene) LEFT JOIN gb_exome.hgmd_allmumt_sum_latest AS h ON (h.gene = t1.Entrez_Gene ) WHERE (t.acc ='HP:0025179' AND g.term1_id = t.id AND g.distance <=20 AND t2.id = g.term2_id) order by g.distance, gene, DiseaseName;