Human Phenotype Ontology

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Hello! Guest! Please Login or Register! Clinician Mode

Examples Gene: MT-ND1, POLG, Region: M:1-1000 Variant: m.8993T>G, 1:g.10042757T>C rs3888511 MSCV_0000006, ClinVar: RCV000000015, Disease: Leigh syndrome, Phenotype: Retinopathy

Grandparent Node:
Abnormal lung morphology (HP:0002088)

Parent Node:
Abnormal pulmonary interstitial morphology (HP:0006530)

..Starting node
..Bronchiolitis obliterans organizing pneumonia (HP:0011945)

Term ID:

11945

Name:

Bronchiolitis obliterans organizing pneumonia

Synonym:

BOOP; Bronchiolitis obliterans organising pneumonia; Cryptogenic organising pneumonia; Cryptogenic organizing pneumonia

Definition:

Bronchiolitis obliterans organizing pneumonia (BOOP) is and interstitial lung abnormalitiy characterized histopathologically by plugs of granulation tissue lying within small airways, alveolar ducts, and alveoli and by chronic inflammatory cell infiltration in alveolar walls. Patients with BOOP generally present with subacute illness, including shortness of breath, fever, malaise, and weight loss.

Comments:

Reference:

HP:0011945

Genes and Diseases:

Child Nodes:

Sister Nodes:

Bronchiolitis obliterans (HP:0011946)

Desquamative interstitial pneumonitis (HP:0005942)

Honeycomb lung (HP:0025175)

Interstitial pneumonitis (HP:0006515)

Intralobular interstitial thickening (HP:0025176)

Lymphocytic interstitial pneumonia (HP:0006527)

Peribronchovascular interstitial thickening (HP:0025177)

Pulmonary interstitial high-resolution computed tomography abnormality (HP:0025389)

Input	HPO ID	HPO term	Distance	Gene	Gene id entrez	HGNC ID	DiseaseId	DiseaseName	ClinVar variants
HPO disease - gene - phenotype typical associations:
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0011945	HP:0011945	Bronchiolitis obliterans organizing pneumonia	0	PIK3CG CL E G H	5294	8978	OMIM:619802	IMMUNODEFICIENCY 97 WITH AUTOINFLAMMATION; IMD97	2
HP:0011945	HP:0011945	Bronchiolitis obliterans organizing pneumonia	0	UNC119 CL E G H	9094	12565	OMIM:615518	IMMUNODEFICIENCY 13; IMD13	30

Genes (2) :PIK3CG UNC119

Diseases (2) :OMIM:619802 OMIM:615518

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.

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