Hearing Loss Disease Portal


 
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Most Common: Hearing Loss (D034381), Deafness (D003638), Sensorineural HL (D006319), Waardenburg Syndrome, Usher Syndromes
Disease Browser
Parent Node:
expandAutoimmune Diseases (D001327)
Parent Node:
expandHemorrhagic Disorders (D006474)
Parent Node:
expandPurpura, Thrombocytopenic (D011696)
..Starting node
..expandPurpura, Thrombocytopenic, Idiopathic (D016553)

       Child Nodes:



 Sister Nodes: 
..expandAcquired amegakaryocytic thrombocytopenia (C538172)
..expandPosttransfusion Purpura (C562868)
..expandPurpura, Thrombocytopenic, Idiopathic (D016553)
..expandPurpura, Thrombotic Thrombocytopenic (D011697) Child1
   

Human Disease MESH is developed by UMLS.
Further data from MedGen, OMIM, CTD
Term ID:9516
Name:Purpura, Thrombocytopenic, Idiopathic
Definition:Thrombocytopenia occurring in the absence of toxic exposure or a disease associated with decreased platelets. It is mediated by immune mechanisms, in most cases IMMUNOGLOBULIN G autoantibodies which attach to platelets and subsequently undergo destruction by macrophages. The disease is seen in acute (affecting children) and chronic (adult) forms.
Alternative IDs:OMIM:188030
ParentIDs:MESH:D001327|MESH:D006474|MESH:D011696
TreeNumbers:C15.378.100.802.687.600 |C15.378.140.855.925.750.600 |C15.378.463.740 |C20.111.759 |C20.841.600 |C23.550.414.950.687.600 |C23.888.885.687.687.600
Synonyms:AITP |Autoimmune Thrombocytopenia |Autoimmune Thrombocytopenias |Autoimmune Thrombocytopenic Purpura |Autoimmune Thrombocytopenic Purpuras |Disease, Werlhof |Disease, Werlhof's |Idiopathic Thrombocytopenic Purpura |Idiopathic Thrombocytopenic Purpuras |Immune Thr
Slim Mappings:Blood disease|Immune system disease|Pathology (process)|Signs and symptoms
Reference: MedGen: D016553
MeSH: D016553
OMIM: 188030;

Genes: FCGR2C;
Phenotypes
1 HP:0000006Autosomal dominant inheritance
2 HP:0001892Abnormal bleeding
3 HP:0003454Platelet antibody positive
4 HP:0001873Thrombocytopenia
Disease Causing ClinVar Variants