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Examples Gene: MT-ND1, POLG, Region: M:1-1000 Variant: m.8993T>G, 1:g.10042757T>C rs3888511 MSCV_0000006, ClinVar: RCV000000015, Disease: Leigh syndrome, Phenotype: Retinopathy

Disease Browser
Parent Node: Gonadal Disorders (D006058)
..Starting node ..Puberty, Precocious (D011629)
Child Nodes:
........Adrenal Hypoplasia, Congenital, with Precocious Puberty (C564568)
........Familial Testotoxicosis (C536961)
........Hypotonia, Seizures, And Precocious Puberty (C567566)
........Leydig Cell Adenoma, Somatic, with Male-Limited Precocious Puberty (C567168)
........Precocious Puberty, Central (C562787)
........Sexual precocity (C538542)
........Spastic paraplegia with precocious puberty (C536874)
........Spondylodysplasia And Premature Pubarche (C567552)
Sister Nodes:
..Disorders of Sex Development (D012734) 107
..Female Athlete Triad Syndrome (D053716)
..Hypogonadism (D007006) 62
..Ovarian Diseases (D010049) 51
..Puberty, Delayed (D011628) 1
..Puberty, Precocious (D011629) 8
..Testicular Diseases (D013733) 28
Human Disease MESH is developed by UMLS. Further data from MedGen, OMIM, CTD

Term ID:	9463
Name:	Puberty, Precocious
Definition:	Development of SEXUAL MATURATION in boys and girls at a chronological age that is 2.5 standard deviations below the mean age at onset of PUBERTY in the population. This early maturation of the hypothalamic-pituitary-gonadal axis results in sexual precocity, elevated serum levels of GONADOTROPINS and GONADAL STEROID HORMONES such as ESTRADIOL and TESTOSTERONE.
Alternative IDs:
ParentIDs:	MESH:D006058
TreeNumbers:	C19.391.693
Synonyms:	Precocious Puberty
Slim Mappings:	Endocrine system disease
Reference:	MedGen: D011629 MeSH: D011629 OMIM: Genes:
Phenotypes
Disease Causing ClinVar Variants