Disease browser and phenotype portal

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MSeqDR-LSDB
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Examples Gene: MT-ND1, POLG, Region: M:1-1000 Variant: m.8993T>G, 1:g.10042757T>C rs3888511 MSCV_0000006, ClinVar: RCV000000015, Disease: Leigh syndrome, Phenotype: Retinopathy

Hearing Loss Disease Portal

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Most Common: Hearing Loss (D034381), Deafness (D003638), Sensorineural HL (D006319), Waardenburg Syndrome, Usher Syndromes

Disease Browser
Parent Node: Paraneoplastic Syndromes, Nervous System (D020361)
Parent Node: Polyneuropathies (D011115)
..Starting node ..Paraneoplastic Polyneuropathy (D020364)
Child Nodes:
Sister Nodes:
..46,Xy Gonadal Dysgenesis, Partial, With Minifascicular Neuropathy (C567773)
..Alcoholic Neuropathy (D020269)
..Aplasia of Extensor Muscles of Fingers, Unilateral, with Generalized Polyneuropathy (C565945)
..Ataxia and Polyneuropathy, Adult-Onset (C564020)
..Deafness, Sensorineural, with Peripheral Neuropathy and Arterial Disease (C565120)
..Hereditary Sensory and Autonomic Neuropathies (D009477) 12
..Hereditary Sensory and Motor Neuropathy (D015417) 164
..Laryngeal Abductor Paralysis with Cerebellar Ataxia and Motor Neuropathy (C565252)
..LEUKOENCEPHALOPATHY WITH DYSTONIA AND MOTOR NEUROPATHY (OMIM:613724)
..Leukoencephalopathy with Dystonia and Motor Neuropathy, SCPx-Deficient (C566654)
..Neuropathy, Hereditary Sensory, Atypical (C564946)
..Optic atrophy polyneuropathy deafness (C537129)
..Paraneoplastic Polyneuropathy (D020364)
..Peripheral Demyelinating Neuropathy, Central Dysmyelination, Waardenburg Syndrome, and Hirschsprung Disease (C563789)
..POEMS Syndrome (D016878)
..Polyneuropathy, Hearing Loss, Ataxia, Retinitis Pigmentosa, And Cataract (C567203)
..Polyradiculoneuropathy (D011129) 18
..Ribose 5-Phosphate Isomerase Deficiency (C563212)
..Severe infantile axonal neuropathy (C537593)
..Tangier Disease (D013631)
Human Disease MESH is developed by UMLS. Further data from MedGen, OMIM, CTD

Term ID:	8610
Name:	Paraneoplastic Polyneuropathy
Definition:	A diffuse or multifocal peripheral neuropathy related to the remote effects of a neoplasm, most often carcinoma or lymphoma. Pathologically, there are inflammatory changes in peripheral nerves. The most common clinical presentation is a symmetric distal mixed sensorimotor polyneuropathy. (Adams et al., Principles of Neurology, 6th ed, p1334)
Alternative IDs:
ParentIDs:	MESH:D011115\|MESH:D020361
TreeNumbers:	C04.588.614.550.700 \|C04.730.856.700 \|C10.574.781.850 \|C10.668.829.800.662
Synonyms:	Neuropathies, Paraneoplastic \|Neuropathies, Paraneoplastic Peripheral \|Neuropathy, Paraneoplastic \|Neuropathy, Paraneoplastic Peripheral \|Paraneoplastic Neuropathies \|Paraneoplastic Neuropathy \|Paraneoplastic Peripheral Neuropathies \|Paraneoplastic Peripheral N
Slim Mappings:	Cancer\|Nervous system disease
Reference:	MedGen: D020364 MeSH: D020364 OMIM: Genes:
Phenotypes
Disease Causing ClinVar Variants