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Examples Gene: MT-ND1, POLG, Region: M:1-1000 Variant: m.8993T>G, 1:g.10042757T>C rs3888511 MSCV_0000006, ClinVar: RCV000000015, Disease: Leigh syndrome, Phenotype: Retinopathy

Disease Browser
Parent Node: Substance-Related Disorders (D019966)
..Starting node ..Opioid-Related Disorders (D009293)
Child Nodes:
........Heroin Dependence (D006556)
........Morphine Dependence (D009021)
Sister Nodes:
..Alcohol-Related Disorders (D019973) 22
..Amphetamine-Related Disorders (D019969)
..Cocaine-Related Disorders (D019970)
..Drug Overdose (D062787)
..Inhalant Abuse (D058545)
..Marijuana Abuse (D002189)
..Neonatal Abstinence Syndrome (D009357)
..Opioid-Related Disorders (D009293) 2
..Phencyclidine Abuse (D010623)
..Psychoses, Substance-Induced (D011605) 1
..Substance Abuse, Intravenous (D015819)
..Substance Withdrawal Syndrome (D013375) 2
..Tobacco Use Disorder (D014029) 1
Human Disease MESH is developed by UMLS. Further data from MedGen, OMIM, CTD

Term ID:

8262

Name:

Opioid-Related Disorders

Definition:

Disorders related or resulting from abuse or mis-use of opioids.

Alternative IDs:

OMIM:610064

ParentIDs:

MESH:D019966

TreeNumbers:

C25.775.675 |F03.900.675

Synonyms:

Slim Mappings:

Mental disorder|Substance-related disorder

Reference:

MedGen: D009293
MeSH: D009293
OMIM: 610064;

Genes:

Phenotypes

Disease Causing ClinVar Variants

Variation_Name	GeneID	GeneSymbol	ClinicalSignificance	dbSNP	RCVaccession	TestedInGTR	PhenotypeIDs	Chromosome	Start	Stop	HGVS_c	HGVS_p	HGVS_g	OtherIDs	Disease_ClinVar	Disease_hgmd
NM_001008503.2(OPRM1):c.118A>G (p.Asn40Asp)	4988	OPRM1	drug response	1799971	RCV000010146; RCV000211310; RCV000211400; RCV000211220; RCV000211345; RCV000211165; RCV000211208; RCV000211332; RCV000211154; RCV000211247; RCV000211368;	N	Gene:100188802,MedGen:C1864733,OMIM:610064; MedGen:CN236463; MedGen:CN236521; MedGen:CN236567; MedGen:CN236590; MedGen:CN236592; MedGen:CN236596; MedGen:CN236601; MedGen:CN236602; MedGen:CN236604; MedGen:CN236606	6	154360797	154360797	NM_001008503.2:c.118A>G	NP_001008503.2:p.Asn40Asp	NC_000006.11:g.154360797A>G	OMIM Allelic Variant:600018.0001,PharmGKB Clinical Annotation:655385241,PharmGKB Clinical Annotation:981204641,PharmGKB Clinical Annotation:982034197,Pha	CN236463 alfentanil response - Metabolism/PK; CN236521 Drugs used in opioid dependence response - Metabolism/PK; CN236590 ethanol response - Toxicity/ADR; CN236592 fentanyl response - Metabolism/PK; CN236596 heroin response - Metabolism/PK; CN236601