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Examples Gene: MT-ND1, POLG, Region: M:1-1000 Variant: m.8993T>G, 1:g.10042757T>C rs3888511 MSCV_0000006, ClinVar: RCV000000015, Disease: Leigh syndrome, Phenotype: Retinopathy

Disease Browser
Parent Node: Insulin Resistance (D007333)
Parent Node: Metabolic Diseases (D008659)
..Starting node ..Metabolic Syndrome X (D024821)
Child Nodes:
........Abdominal obesity metabolic syndrome (C535554)
Sister Nodes:
..Acid-Base Imbalance (D000137) 42
..ADIPONECTIN, SERUM LEVEL OF, QUANTITATIVE TRAIT LOCUS 2 (OMIM:606770)
..ADIPONECTIN, SERUM LEVEL OF, QUANTITATIVE TRAIT LOCUS 3 (OMIM:606771)
..Brain Diseases, Metabolic (D001928) 244
..Calcium Metabolism Disorders (D002128) 94
..DNA Repair-Deficiency Disorders (D049914) 95
..Glucose Metabolism Disorders (D044882) 137
..Hyperlactatemia (D065906)
..Hypermanganesemia with Dystonia Polycythemia and Cirrhosis (C548016)
..Iron Metabolism Disorders (D019189) 23
..Lipid Metabolism Disorders (D052439) 189
..Malabsorption Syndromes (D008286) 29
..Metabolic Syndrome X (D024821) 1
..Metabolism, Inborn Errors (D008661) 886
..Mitochondrial Diseases (D028361) 114
..Phosphorus Metabolism Disorders (D010760) 25
..Porphyrias (D011164) 18
..Proteostasis Deficiencies (D057165) 55
..SHORT syndrome (C537327)
..Skin Diseases, Metabolic (D012875) 33
..Wasting Syndrome (D019282) 1
..Water-Electrolyte Imbalance (D014883) 31
Human Disease MESH is developed by UMLS. Further data from MedGen, OMIM, CTD

Term ID:	7110
Name:	Metabolic Syndrome X
Definition:	A cluster of metabolic risk factors for CARDIOVASCULAR DISEASES and TYPE 2 DIABETES MELLITUS. The major components of metabolic syndrome X include excess ABDOMINAL FAT; atherogenic DYSLIPIDEMIA; HYPERTENSION; HYPERGLYCEMIA; INSULIN RESISTANCE; a proinflammatory state; and a prothrombotic (THROMBOSIS) state. (from AHA/NHLBI/ADA Conference Proceedings, Circulation 2004; 109:551-556)
Alternative IDs:
ParentIDs:	MESH:D007333\|MESH:D008659
TreeNumbers:	C18.452.394.968.500.570 \|C18.452.625
Synonyms:	Cardiovascular Syndrome, Metabolic \|Cardiovascular Syndromes, Metabolic \|Dysmetabolic Syndrome X \|Insulin Resistance Syndrome X \|Metabolic Cardiovascular Syndrome \|Metabolic X Syndrome \|Reaven Syndrome X \|Syndrome, Metabolic Cardiovascular \|Syndrome, Metabolic X
Slim Mappings:	Metabolic disease
Reference:	MedGen: D024821 MeSH: D024821 OMIM: Genes:
Phenotypes
Disease Causing ClinVar Variants