Hearing Loss Disease Portal


 
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Most Common: Hearing Loss (D034381), Deafness (D003638), Sensorineural HL (D006319), Waardenburg Syndrome, Usher Syndromes
Disease Browser
Parent Node:
expandAutoimmune Diseases (D001327)
Parent Node:
expandDiabetes Mellitus (D003920)
..Starting node
..expandDiabetes Mellitus, Type 1 (D003922)

       Child Nodes:
........expandBangstad syndrome (C537902)
........expandDiabetes Mellitus, Insulin-Dependent, 10 (C566602)
........expandDiabetes Mellitus, Insulin-Dependent, 11 (C563371)
........expandDiabetes Mellitus, Insulin-Dependent, 12 (C563326)
........expandDiabetes Mellitus, Insulin-Dependent, 13 (C563352)
........expandDiabetes Mellitus, Insulin-Dependent, 15 (C566645)
........expandDiabetes Mellitus, Insulin-Dependent, 17 (C566395)
........expandDiabetes Mellitus, Insulin-Dependent, 18 (C565315)
........expandDiabetes Mellitus, Insulin-Dependent, 19 (C565715)
........expandDiabetes Mellitus, Insulin-Dependent, 2 (C565100)
........expandDiabetes Mellitus, Insulin-Dependent, 20 (C567286)
........expandDiabetes Mellitus, Insulin-Dependent, 21 (C567285)
........expandDiabetes Mellitus, Insulin-Dependent, 22 (C567284)
........expandDiabetes Mellitus, Insulin-Dependent, 23 (C567233)
........expandDiabetes Mellitus, Insulin-Dependent, 24 (C567818)
........expandDiabetes Mellitus, Insulin-Dependent, 3 (C563960)
........expandDiabetes Mellitus, Insulin-Dependent, 4 (C563959)
........expandDiabetes Mellitus, Insulin-Dependent, 5 (C563958)
........expandDiabetes Mellitus, Insulin-Dependent, 6 (C566603)
........expandDiabetes Mellitus, Insulin-Dependent, 7 (C563957)
........expandDiabetes Mellitus, Insulin-Dependent, 8 (C563433)
........expandDIABETES MELLITUS, INSULIN-DEPENDENT, X-LINKED, SUSCEPTIBILITY TO (OMIM:300136)
........expandRenal Tubulopathy, Diabetes Mellitus, and Cerebellar Ataxia due to Duplication of Mitochondrial DNA (C564014)
........expandWolcott-Rallison syndrome (C536739)
........expandWolfram Syndrome (D014929) Child1



 Sister Nodes: 
..expand6q24-Related Transient Neonatal Diabetes Mellitus (C579872)
..expandAlaninuria with Microcephaly, Dwarfism, Enamel Hypoplasia, and Diabetes Mellitus (C565968)
..expandAtherosclerosis, Premature, with Deafness, Nephropathy, Diabetes Mellitus, Photomyoclonus, and Degenerative Neurologic Disease (C565928)
..expandDevelopmental Delay, Epilepsy, and Neonatal Diabetes (C565253)
..expandDiabetes Complications (D048909) Child23
..expandDiabetes Mellitus, Congenital Autoimmune (C565730)
..expandDiabetes Mellitus, Experimental (D003921)
..expandDiabetes Mellitus, Insulin-Resistant, with Acanthosis Nigricans (C562710)
..expandDiabetes Mellitus, Neonatal, with Congenital Hypothyroidism (C565705)
..expandDiabetes Mellitus, Permanent Neonatal (C563425)
..expandDiabetes Mellitus, Permanent Neonatal, with Cerebellar Agenesis (C563796)
..expandDiabetes Mellitus, Permanent Neonatal, With Neurologic Features (C563424)
..expandDiabetes Mellitus, Transient Neonatal, 1 (C563322)
..expandDiabetes Mellitus, Transient Neonatal, 2 (C563672)
..expandDiabetes Mellitus, Transient Neonatal, 3 (C566432)
..expandDiabetes Mellitus, Type 1 (D003922) Child26
..expandDiabetes Mellitus, Type 2 (D003924) Child17
..expandDiabetes, Gestational (D016640) Child5
..expandDiabetic Ketoacidosis (D016883)
..expandDonohue Syndrome (D056731) Child1
..expandFeigenbaum Bergeron Richardson syndrome (C536178)
..expandFurukawa Takagi Nakao syndrome (C538193)
..expandHerrmann syndrome (C538113)
..expandHyperproinsulinemia (C562776)
..expandLipoatrophy with diabetes, hepatic steatosis, cardiomyopathy, and leukomelanodermic papules (C535905)
..expandLymphedema-Distichiasis Syndrome with Renal Disease and Diabetes Mellitus (C567188)
..expandMartinez-Frias Syndrome (C563346)
..expandMATURITY-ONSET DIABETES OF THE YOUNG, TYPE 10 (OMIM:613370)
..expandMATURITY-ONSET DIABETES OF THE YOUNG, TYPE 11 (OMIM:613375)
..expandMaturity-Onset Diabetes of the Young, Type 7 (C566466)
..expandMitchell-Riley Syndrome (C567570)
..expandMitochondrial Myopathy with Diabetes (C564026)
..expandMuscular Atrophy, Ataxia, Retinitis Pigmentosa, and Diabetes Mellitus (C562774)
..expandPancreatic beta cell agenesis with neonatal diabetes mellitus (C538111)
..expandPancreatic Hypoplasia, Congenital, with Diabetes Mellitus and Congenital Heart Disease (C564011)
..expandPrediabetic State (D011236)
..expandPremature aging, Okamoto type (C535270)
..expandThiamine responsive megaloblastic anemia syndrome (C536510)
..expandWolfram Syndrome, Mitochondrial Form (C564012)
..expandWoodhouse Sakati syndrome (C536742)
..expandYorifuji Okuno syndrome (C536714)
   

Human Disease MESH is developed by UMLS.
Further data from MedGen, OMIM, CTD
Term ID:3306
Name:Diabetes Mellitus, Type 1
Definition:A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.
Alternative IDs:OMIM:222100|OMIM:612227
ParentIDs:MESH:D001327|MESH:D003920
TreeNumbers:C18.452.394.750.124 |C19.246.267 |C20.111.327
Synonyms:Autoimmune Diabetes |Brittle Diabetes Mellitus |Diabetes, Autoimmune |Diabetes, Juvenile-Onset |Diabetes Mellitus, Brittle |Diabetes Mellitus, Insulin Dependent |Diabetes Mellitus, Insulin-Dependent |Diabetes Mellitus, Insulin-Dependent, 1 |Diabetes Mellitus, Ju
Slim Mappings:Endocrine system disease|Immune system disease|Metabolic disease
Reference: MedGen: D003922
MeSH: D003922
OMIM: 612227;

Genes: AF8T; FOXP3; HNF1A; ITPR3; OAS1; PAX4; PTPN22;
Phenotypes
1 HP:0002960Autoimmunity
2 HP:0000006Autosomal dominant inheritance
3 HP:0006279Beta-cell dysfunction
4 HP:0000819Diabetes mellitus
5 HP:0000855Insulin resistance
6 HP:0001993Ketoacidosis
7 HP:0001426Multifactorial inheritance
Disease Causing ClinVar Variants