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Examples Gene: MT-ND1, POLG, Region: M:1-1000 Variant: m.8993T>G, 1:g.10042757T>C rs3888511 MSCV_0000006, ClinVar: RCV000000015, Disease: Leigh syndrome, Phenotype: Retinopathy

Disease Browser
Parent Node: Alcohol-Related Disorders (D019973)
Parent Node: Brain Diseases, Metabolic (D001928)
Parent Node: Thiamine Deficiency (D013832)
..Starting node ..Wernicke Encephalopathy (D014899)
Child Nodes:
Sister Nodes:
..Beriberi (D001602)
..Wernicke Encephalopathy (D014899)
Human Disease MESH is developed by UMLS. Further data from MedGen, OMIM, CTD

Term ID:	11730
Name:	Wernicke Encephalopathy
Definition:	An acute neurological disorder characterized by the triad of ophthalmoplegia, ataxia, and disturbances of mental activity or consciousness. Eye movement abnormalities include nystagmus, external rectus palsies, and reduced conjugate gaze. THIAMINE DEFICIENCY and chronic ALCOHOLISM are associated conditions. Pathologic features include periventricular petechial hemorrhages and neuropil breakdown in the diencephalon and brainstem. Chronic thiamine deficiency may lead to KORSAKOFF SYNDROME. (Adams et al., Principles of Neurology, 6th ed, pp1139-42; Davis & Robertson, Textbook of Neuropathology, 2nd ed, pp452-3)
Alternative IDs:
ParentIDs:	MESH:D001928\|MESH:D013832\|MESH:D019973
TreeNumbers:	C10.228.140.163.960 \|C18.452.132.960 \|C18.654.521.500.133.699.827.822 \|C25.775.100.625 \|F03.900.100.875
Synonyms:	Beriberi, Cerebral \|Cerebral Beriberi \|Encephalopathies, Wernicke \|Encephalopathy, Gayet Wernicke \|Encephalopathy, Gayet-Wernicke \|Encephalopathy, Wernicke \|Encephalopathy, Wernickes \|Encephalopathy, Wernicke's \|Gayet Wernicke Encephalopathy \|Gayet-Wernicke Encep
Slim Mappings:	Mental disorder\|Metabolic disease\|Nervous system disease\|Nutrition disorder\|Substance-related disorder
Reference:	MedGen: D014899 MeSH: D014899 OMIM: Genes:
Phenotypes
Disease Causing ClinVar Variants