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Examples Gene: MT-ND1, POLG, Region: M:1-1000 Variant: m.8993T>G, 1:g.10042757T>C rs3888511 MSCV_0000006, ClinVar: RCV000000015, Disease: Leigh syndrome, Phenotype: Retinopathy

MSeqDR Central Portal

MSeqDR Data Summary for the Term TNFRSF10B:

Ensembl Gene ID	Associated Gene Name	LSDB Genes	LSDB Variants	clinVar hits	Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID	Description	Chr	Gene Start	Gene End	Strand	Band	Transcript Start bp	Transcript End bp	Associated Gene Name	Associated Transcript Name	Associated Gene DB	Associated Transcript DB	Transcript count	pct GC content	Gene Biotype	Transcript Biotype	Source Gene	Source Transcript	Status gene	Status transcript	EntrezGene ID	HGNC ID	HGNC Symbol	RefSeq mRNA	Seq region id
ENSG00000120889	TNFRSF10B	0	0	1	ENSG00000120889	ENST00000523752		tumor necrosis factor receptor superfamily, member 10b [Source:HGNC Symbol;Acc:11905]	8	22877646	22926692	-1	p21.3	22877646	22885481	TNFRSF10B	TNFRSF10B-004	HGNC Symbol	HGNC transcript name	9	43.23	protein_coding	retained_intron	ensembl_hava	havana	KNOWN	KNOWN	8795	11905	TNFRSF10B		27523

MSeqDR Master Exome Data Set M1: 229 entries from same gene

No.	Chr	Position	Reference	Variant	EnsemblTranscriptID	EnsemblGeneID	Gene_Start	Gene_End	EnsemblProteinID	Gene	strand	Uniprot	cChange	pChange	Nature	dbSNP	Freq	EVS	phastCons	SIFT	Polyphen	HGMD	type	samples
1	8	22877681	G	A	ENST00000276431	ENSG00000120889	22877646	22926692	ENSP00000276431	TNFRSF10B	-1	TR10B_HUMAN	-	-	3'_UTR	NA	-	-	lod=189:529	DAMAGING	-	-	het	1
2	8	22877681	G	A	ENST00000523752	ENSG00000120889	22877646	22926692	-	TNFRSF10B	-1	-	c.3293C>T	p.S1098F	non-syn	NA	-	-	lod=189:529	DAMAGING	-	-	het	1
3	8	22877798	C	T	ENST00000276431	ENSG00000120889	22877646	22926692	ENSP00000276431	TNFRSF10B	-1	TR10B_HUMAN	-	-	3'_UTR	NA	-	-	-	-	-	-	het	1
4	8	22877798	C	T	ENST00000523752	ENSG00000120889	22877646	22926692	-	TNFRSF10B	-1	-	c.3176G>A	p.C1059Y	non-syn	NA	-	-	-	-	-	-	het	1
5	8	22877897	C	T	ENST00000276431	ENSG00000120889	22877646	22926692	ENSP00000276431	TNFRSF10B	-1	TR10B_HUMAN	-	-	3'_UTR	NA	-	-	-	-	-	-	het	1
6	8	22877897	C	T	ENST00000523752	ENSG00000120889	22877646	22926692	-	TNFRSF10B	-1	-	c.3077G>A	p.R1026Q	non-syn	NA	-	-	-	-	-	-	het	1
7	8	22878099	G	A	ENST00000276431	ENSG00000120889	22877646	22926692	ENSP00000276431	TNFRSF10B	-1	TR10B_HUMAN	-	-	3'_UTR	NA	-	-	-	-	-	-	het	1
8	8	22878099	G	A	ENST00000523752	ENSG00000120889	22877646	22926692	-	TNFRSF10B	-1	-	c.2875C>T	p.R959W	non-syn	NA	-	-	-	-	-	-	het	1
9	8	22878183	C	T	ENST00000276431	ENSG00000120889	22877646	22926692	ENSP00000276431	TNFRSF10B	-1	TR10B_HUMAN	-	-	3'_UTR	NA	-	-	-	-	-	-	het	1
10	8	22878183	C	T	ENST00000523752	ENSG00000120889	22877646	22926692	-	TNFRSF10B	-1	-	c.2791G>A	p.A931T	non-syn	NA	-	-	-	-	-	-	het	1
11	8	22878326	G	C	ENST00000276431	ENSG00000120889	22877646	22926692	ENSP00000276431	TNFRSF10B	-1	TR10B_HUMAN	-	-	3'_UTR	rs35974498	0.03668	-	-	-	-	-	hom	5
12	8	22878326	G	C	ENST00000276431	ENSG00000120889	22877646	22926692	ENSP00000276431	TNFRSF10B	-1	TR10B_HUMAN	-	-	3'_UTR	rs35974498	0.03668	-	-	-	-	-	het	67
13	8	22878326	G	C	ENST00000523752	ENSG00000120889	22877646	22926692	-	TNFRSF10B	-1	-	c.2648C>G	p.A883G	non-syn	rs35974498	0.03668	-	-	-	-	-	hom	5
14	8	22878326	G	C	ENST00000523752	ENSG00000120889	22877646	22926692	-	TNFRSF10B	-1	-	c.2648C>G	p.A883G	non-syn	rs35974498	0.03668	-	-	-	-	-	het	67
15	8	22878564	G	A	ENST00000276431	ENSG00000120889	22877646	22926692	ENSP00000276431	TNFRSF10B	-1	TR10B_HUMAN	-	-	3'_UTR	NA	-	-	-	-	-	-	het	1
16	8	22878564	G	A	ENST00000523752	ENSG00000120889	22877646	22926692	-	TNFRSF10B	-1	-	c.2410C>T	p.R804W	non-syn	NA	-	-	-	-	-	-	het	1
17	8	22878742	T	C	ENST00000276431	ENSG00000120889	22877646	22926692	ENSP00000276431	TNFRSF10B	-1	TR10B_HUMAN	-	-	3'_UTR	rs192781747	0.00273	-	-	-	-	-	het	3
18	8	22878742	T	C	ENST00000523752	ENSG00000120889	22877646	22926692	-	TNFRSF10B	-1	-	c.2232A>G	p.A744A	syn	rs192781747	0.00273	-	-	-	-	-	het	3
19	8	22878835	G	A	ENST00000276431	ENSG00000120889	22877646	22926692	ENSP00000276431	TNFRSF10B	-1	TR10B_HUMAN	-	-	3'_UTR	NA	-	-	-	-	-	-	het	1
20	8	22878835	G	A	ENST00000523752	ENSG00000120889	22877646	22926692	-	TNFRSF10B	-1	-	c.2139C>T	p.Y713Y	syn	NA	-	-	-	-	-	-	het	1

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Transcripts and variants in the surrounding TNFRSF10B 8:22877646..22926692 region Gbrowse