MSeqDR Mitochondrial disease browser phenotype pathogenic gene and mutation portal

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Examples Gene: MT-ND1, POLG, Region: M:1-1000 Variant: m.8993T>G, 1:g.10042757T>C rs3888511 MSCV_0000006, ClinVar: RCV000000015, Disease: Leigh syndrome, Phenotype: Retinopathy

*:HP: HPO terms, ND: NAMDC terms.
Most Studied CPEO, Complex I Deficiency, COXPD1, Leigh, LHON, MELAS, MERRF, NARP, SANDO

Disease Browser
Parent Node: arthritis (MONDO:0005578)
Parent Node: cartilage disease (MONDO:0005569)
Parent Node: vertebral joint disease (MONDO:0037847)
..Starting node ..discitis ()
Child Nodes:
Sister Nodes:
..ankylosing spondylitis ()
..discitis ()
..intervertebral disc degenerative disorder ()
MONDO is developed by the Monarch Initiative. Human Disease MESH is developed by UMLS. Further data from MedGen, OMIM,ClinVar, CTD

Term ID:	6728
Name:	discitis
Definition:	Inflammation of an intervertebral disc or disk space which may lead to disk erosion. Until recently, discitis has been defined as a nonbacterial inflammation and has been attributed to aseptic processes (e.g., chemical reaction to an injected substance). However, recent studies provide evidence that infection may be the initial cause, but perhaps not the promoter, of most cases of discitis. Discitis has been diagnosed in patients following discography, myelography, lumbar puncture, paravertebral injection, and obstetrical epidural anesthesia. Discitis following chemonucleolysis (especially with chymopapain) is attributed to chemical reaction by some and to introduction of microorganisms by others.
Alternative IDs:
ParentIDs:
TreeNumbers:
Synonyms:	inflammation of intervertebral disk; intervertebral disk inflammation
Slim Mappings:
Reference:	MedGen: MeSH: OMIM: MSeqDR : Genes:
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