A usually aggressive, poorly differentiated invasive adenocarcinoma characterized by the presence of malignant glandular cells in which the nucleus is pressed to one side by the presence of intracytoplasmic mucus. It may arise from the stomach, small and large intestine, ampulla of Vater, appendix, gallbladder, pancreas, lung, bladder, breast, and prostate gland.
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Synonyms:
signet ring carcinoma; signet ring carcinoma NOS (morphologic abnormality); signet ring cell adenocarcinoma; signet ring cell carcinoma; signet ring cell carcinoma (morphologic abnormality)
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MedGen: MeSH: OMIM: MSeqDR : Genes:
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Disease Causing ClinVar Variants
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