Human Phenotype Ontology 
Grandparent Node:
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Abnormality of the integument (HP:0001574)help
Parent Node:
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Abnormality of skin adnexa physiology (HP:0025276)help
..Starting node
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Anhidrosis (HP:0000970)help
Term ID: 970
Name: Anhidrosis
Synonym: Anhydrosis; Lack of sweating; Sudomotor dysfunction; Sweating dysfunction
Definition: Inability to sweat.
Comments:
Reference: HP:0000970
Genes and Diseases:
 
       Child Nodes:

 Sister Nodes: 
..expandCold-induced sweating (HP:0025278) help
..expandGeneralized anhidrosis (HP:0007459) help
..expandGustatory sweating (HP:0025277) help
..expandHypohidrosis or hyperhidrosis (HP:0007550) help
..expandIpsilateral lack of facial sweating (HP:0007451) help
InputHPO IDHPO termDistanceGeneGene id entrezDiseaseIdDiseaseNameDiseaseMIMConceptIDSourceTypical associationHGMD variantsClinVar variantsHGNC IDGeneMIM
 
HPO disease - gene - phenotype typical associations:
HP:0000970HP:0000970Anhidrosis0BCS1L CL E G H617262000Pili torti-deafness syndrome262000C0266006OMIM12791020603647
HP:0000970HP:0000970Anhidrosis0BCS1L CL E G H617262000Pili torti-deafness syndrome262000C0266006OMIM12491020603647
HP:0000970HP:0000970Anhidrosis0EDA CL E G H1896305100Hypohidrotic X-linked ectodermal dysplasia305100C0162359OMIM14953157300451
HP:0000970HP:0000970Anhidrosis0EDA CL E G H1896305100Hypohidrotic X-linked ectodermal dysplasia305100C0162359OMIM14603157300451
HP:0000970HP:0000970Anhidrosis0EDAR CL E G H10913224900Autosomal recessive hypohidrotic ectodermal dysplasia syndrome224900C0406702OMIM12912895604095
HP:0000970HP:0000970Anhidrosis0EDAR CL E G H10913224900Autosomal recessive hypohidrotic ectodermal dysplasia syndrome224900C0406702OMIM12782895604095
HP:0000970HP:0000970Anhidrosis0EDARADD CL E G H128178224900Autosomal recessive hypohidrotic ectodermal dysplasia syndrome224900C0406702OMIM119414341606603
HP:0000970HP:0000970Anhidrosis0EDARADD CL E G H128178224900Autosomal recessive hypohidrotic ectodermal dysplasia syndrome224900C0406702OMIM118814341606603
HP:0000970HP:0000970Anhidrosis0EDARADD CL E G H128178614940Ectodermal dysplasia 11a, hypohidrotic/hair/tooth type, autosomal dominant614940C3541517OMIM119414341606603
HP:0000970HP:0000970Anhidrosis0EDARADD CL E G H128178614940Ectodermal dysplasia 11a, hypohidrotic/hair/tooth type, autosomal dominant614940C3541517OMIM118814341606603
HP:0000970HP:0000970Anhidrosis0EDARADD CL E G H128178614941Ectodermal dysplasia 11b, hypohidrotic/hair/tooth type, autosomal recessive614941C3539920OMIM119414341606603
HP:0000970HP:0000970Anhidrosis0EDARADD CL E G H128178614941Ectodermal dysplasia 11b, hypohidrotic/hair/tooth type, autosomal recessive614941C3539920OMIM118814341606603
HP:0000970HP:0000970Anhidrosis0ERCC6 CL E G H2074133540Cockayne syndrome B133540C0751038OMIM19463438609413
HP:0000970HP:0000970Anhidrosis0ERCC6 CL E G H2074133540Cockayne syndrome B133540C0751038OMIM18253438609413
HP:0000970HP:0000970Anhidrosis0ERCC8 CL E G H1161216400Cockayne syndrome type A216400C0751039OMIM13433439609412
HP:0000970HP:0000970Anhidrosis0ERCC8 CL E G H1161216400Cockayne syndrome type A216400C0751039OMIM13103439609412
HP:0000970HP:0000970Anhidrosis0FUCA1 CL E G H2517230000Fucosidosis230000C0016788OMIM11884006612280
HP:0000970HP:0000970Anhidrosis0FUCA1 CL E G H2517230000Fucosidosis230000C0016788OMIM11374006612280
HP:0000970HP:0000970Anhidrosis0ITPR2 CL E G H3709106190Anhidrosis, isolated, with normal sweat glands106190C1862871OMIM1666181600144
HP:0000970HP:0000970Anhidrosis0ITPR2 CL E G H3709106190Anhidrosis, isolated, with normal sweat glands106190C1862871OMIM1656181600144
HP:0000970HP:0000970Anhidrosis0KIF1A CL E G H547201300Hereditary sensory and autonomic neuropathy type IIA201300C2752089OMIM11735888601255
HP:0000970HP:0000970Anhidrosis0KIF1A CL E G H547201300Hereditary sensory and autonomic neuropathy type IIA201300C2752089OMIM11441888601255
HP:0000970HP:0000970Anhidrosis0MBTPS2 CL E G H51360659AmyoplasiaORPHA124215455300294
HP:0000970HP:0000970Anhidrosis0MBTPS2 CL E G H51360659AmyoplasiaORPHA123115455300294
HP:0000970HP:0000970Anhidrosis0NFKBIA CL E G H4792612132Ectodermal dysplasia, anhidrotic, with T-cell immunodeficiency, autosomal dominant612132C2677481OMIM11767797164008
HP:0000970HP:0000970Anhidrosis0NFKBIA CL E G H4792612132Ectodermal dysplasia, anhidrotic, with T-cell immunodeficiency, autosomal dominant612132C2677481OMIM11527797164008
HP:0000970HP:0000970Anhidrosis0NGF CL E G H480364752ORPHA11477808162030
HP:0000970HP:0000970Anhidrosis0NGF CL E G H480364752ORPHA11217808162030
HP:0000970HP:0000970Anhidrosis0NTRK1 CL E G H491464752ORPHA18208031191315
HP:0000970HP:0000970Anhidrosis0NTRK1 CL E G H491464752ORPHA17328031191315
HP:0000970HP:0000970Anhidrosis0NTRK1 CL E G H4914256800Hereditary insensitivity to pain with anhidrosis256800C0020074OMIM18208031191315
HP:0000970HP:0000970Anhidrosis0NTRK1 CL E G H4914256800Hereditary insensitivity to pain with anhidrosis256800C0020074OMIM17328031191315
HP:0000970HP:0000970Anhidrosis0RETREG1 CL E G H54463201300Hereditary sensory and autonomic neuropathy type IIA201300C2752089OMIM141625964613114
HP:0000970HP:0000970Anhidrosis0RETREG1 CL E G H54463201300Hereditary sensory and autonomic neuropathy type IIA201300C2752089OMIM136825964613114
HP:0000970HP:0000970Anhidrosis0SCN9A CL E G H6335201300Hereditary sensory and autonomic neuropathy type IIA201300C2752089OMIM1170810597603415
HP:0000970HP:0000970Anhidrosis0SCN9A CL E G H6335201300Hereditary sensory and autonomic neuropathy type IIA201300C2752089OMIM1143810597603415
HP:0000970HP:0000970Anhidrosis0SCN9A CL E G H6335243000Indifference to pain, congenital, autosomal recessive243000C1855739OMIM1170810597603415
HP:0000970HP:0000970Anhidrosis0SCN9A CL E G H6335243000Indifference to pain, congenital, autosomal recessive243000C1855739OMIM1143810597603415
HP:0000970HP:0000970Anhidrosis0SPTLC2 CL E G H9517613640Hereditary sensory and autonomic neuropathy type IC613640C3150896OMIM148411278605713
HP:0000970HP:0000970Anhidrosis0SPTLC2 CL E G H9517613640Hereditary sensory and autonomic neuropathy type IC613640C3150896OMIM144411278605713
HP:0000970HP:0000970Anhidrosis0TP63 CL E G H8626106260Hay-Wells syndrome of ectodermal dysplasia106260C0406709OMIM144415979603273
HP:0000970HP:0000970Anhidrosis0TP63 CL E G H8626106260Hay-Wells syndrome of ectodermal dysplasia106260C0406709OMIM137615979603273
HP:0000970HP:0000970Anhidrosis0TRPV3 CL E G H162514659AmyoplasiaORPHA133718084607066
HP:0000970HP:0000970Anhidrosis0TRPV3 CL E G H162514659AmyoplasiaORPHA132918084607066
HP:0000970HP:0000970Anhidrosis0WNK1 CL E G H65125201300Hereditary sensory and autonomic neuropathy type IIA201300C2752089OMIM1125814540605232
HP:0000970HP:0000970Anhidrosis0WNK1 CL E G H65125201300Hereditary sensory and autonomic neuropathy type IIA201300C2752089OMIM1109614540605232
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0000970HP:0000970Anhidrosis0NGF CL E G H4803608654Congenital sensory neuropathy with selective loss of small myelinated fibers608654C0020075OMIM01477808162030
HP:0000970HP:0000970Anhidrosis0NGF CL E G H4803608654Congenital sensory neuropathy with selective loss of small myelinated fibers608654C0020075OMIM01217808162030
HP:0000970HP:0000970Anhidrosis0NGLY1 CL E G H55768615273Congenital disorder of deglycosylation615273C3808991OMIM048517646610661
HP:0000970HP:0000970Anhidrosis0NGLY1 CL E G H55768615273Congenital disorder of deglycosylation615273C3808991OMIM038117646610661


Genes (20) :BCS1L EDA EDAR EDARADD ERCC6 ERCC8 FUCA1 ITPR2 KIF1A MBTPS2 NFKBIA NGF NGLY1 NTRK1 RETREG1 SCN9A SPTLC2 TP63 TRPV3 WNK1

Diseases (19) :262000 305100 224900 614940 614941 133540 216400 230000 106190 201300 659 612132 64752 608654 615273 256800 243000 613640 106260
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is August 2021 release.