Human Phenotype Ontology

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Hello! Guest! Please Login or Register! Clinician Mode

Examples Gene: MT-ND1, POLG, Region: M:1-1000 Variant: m.8993T>G, 1:g.10042757T>C rs3888511 MSCV_0000006, ClinVar: RCV000000015, Disease: Leigh syndrome, Phenotype: Retinopathy

Grandparent Node:
Abnormal internal genitalia (HP:0000812)

Grandparent Node:
Abnormality of the male genitalia (HP:0010461)

Parent Node:
Abnormal male internal genitalia morphology (HP:0000022)

..Starting node
..Abnormal prostate morphology (HP:0008775)

Term ID:

8775

Name:

Abnormal prostate morphology

Synonym:

Abnormality of the prostate

Definition:

An abnormality of the prostate.

Comments:

Reference:

HP:0008775

Genes and Diseases:

Child Nodes:

........

Prostatitis (HP:0000024)

........

Hypoplasia of the prostate (HP:0008687)

........

Benign prostatic hyperplasia (HP:0008711)

........

Prominent prostate median bar (HP:0008742)

........

Prostate neoplasm (HP:0100787)

................... HP:0012125 Prostate cancer

Sister Nodes:

Abnormal epididymis morphology (HP:0009714)

Abnormal vas deferens morphology (HP:0012872)

Input	HPO ID	HPO term	Distance	Gene	Gene id entrez	HGNC ID	DiseaseId	DiseaseName	Frequency	ClinVar variants
HPO disease - gene - phenotype typical associations:
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0008775	HP:0008775	Abnormal prostate morphology	0	AAGAB CL E G H	79719	25662	ORPHA:79501	Punctate palmoplantar keratoderma type 1		7
HP:0008775	HP:0008775	Abnormal prostate morphology	0	APC CL E G H	324	583	ORPHA:79665	Gardner syndrome		3179
HP:0008775	HP:0008775	Abnormal prostate morphology	0	AR CL E G H	367	644	OMIM:176807	Prostate cancer		125
HP:0008775	HP:0008775	Abnormal prostate morphology	0	BARD1 CL E G H	580	952	ORPHA:145	Hereditary breast and ovarian cancer syndrome		790
HP:0008775	HP:0008775	Abnormal prostate morphology	0	BMPR1A CL E G H	657	1076	ORPHA:157794	Hereditary mixed polyposis syndrome		385
HP:0008775	HP:0008775	Abnormal prostate morphology	0	BRCA1 CL E G H	672	1100	ORPHA:145	Hereditary breast and ovarian cancer syndrome		5769
HP:0008775	HP:0008775	Abnormal prostate morphology	0	BRCA2 CL E G H	675	1101	ORPHA:145	Hereditary breast and ovarian cancer syndrome		7642
HP:0008775	HP:0008775	Abnormal prostate morphology	0	BRCA2 CL E G H	675	1101	OMIM:176807	Prostate cancer		7642
HP:0008775	HP:0008775	Abnormal prostate morphology	0	BRIP1 CL E G H	83990	20473	ORPHA:145	Hereditary breast and ovarian cancer syndrome		1086
HP:0008775	HP:0008775	Abnormal prostate morphology	0	BTK CL E G H	695	1133	OMIM:300755	Agammaglobulinemia, X-linked		109
HP:0008775	HP:0008775	Abnormal prostate morphology	0	BTK CL E G H	695	1133	OMIM:307200	Isolated growth hormone deficiency, type III, with agammaglobulinemia		109
HP:0008775	HP:0008775	Abnormal prostate morphology	0	CDH1 CL E G H	999	1748	OMIM:176807	Prostate cancer		1003
HP:0008775	HP:0008775	Abnormal prostate morphology	0	CDKN2A CL E G H	1029	1787	ORPHA:524	Li-Fraumeni syndrome		289
HP:0008775	HP:0008775	Abnormal prostate morphology	0	CHEK2 CL E G H	11200	16627	ORPHA:145	Hereditary breast and ovarian cancer syndrome		833
HP:0008775	HP:0008775	Abnormal prostate morphology	0	CHEK2 CL E G H	11200	16627	ORPHA:524	Li-Fraumeni syndrome		833
HP:0008775	HP:0008775	Abnormal prostate morphology	0	CHEK2 CL E G H	11200	16627	OMIM:176807	Prostate cancer		833
HP:0008775	HP:0008775	Abnormal prostate morphology	0	COL14A1 CL E G H	7373	2191	ORPHA:79501	Punctate palmoplantar keratoderma type 1		2
HP:0008775	HP:0008775	Abnormal prostate morphology	0	CTLA4 CL E G H	1493	2505	ORPHA:900	Granulomatosis with polyangiitis		10
HP:0008775	HP:0008775	Abnormal prostate morphology	0	EPHB2 CL E G H	2048	3393	OMIM:603688	Prostate cancer/brain cancer susceptibility		7
HP:0008775	HP:0008775	Abnormal prostate morphology	0	FOXE1 CL E G H	2304	3806	OMIM:616534	Thyroid cancer, nonmedullary, 4		9
HP:0008775	HP:0008775	Abnormal prostate morphology	0	GREM1 CL E G H	26585	2001	ORPHA:157794	Hereditary mixed polyposis syndrome		9
HP:0008775	HP:0008775	Abnormal prostate morphology	0	HGD CL E G H	3081	4892	ORPHA:56	Alkaptonuria		77
HP:0008775	HP:0008775	Abnormal prostate morphology	0	HLA-DPA1 CL E G H	3113	4938	ORPHA:900	Granulomatosis with polyangiitis
HP:0008775	HP:0008775	Abnormal prostate morphology	0	HLA-DPB1 CL E G H	3115	4940	ORPHA:900	Granulomatosis with polyangiitis		1
HP:0008775	HP:0008775	Abnormal prostate morphology	0	KLF6 CL E G H	1316	2235	OMIM:176807	Prostate cancer		18
HP:0008775	HP:0008775	Abnormal prostate morphology	0	MAD1L1 CL E G H	8379	6762	OMIM:176807	Prostate cancer		5
HP:0008775	HP:0008775	Abnormal prostate morphology	0	MDM2 CL E G H	4193	6973	ORPHA:524	Li-Fraumeni syndrome		1
HP:0008775	HP:0008775	Abnormal prostate morphology	0	MRE11 CL E G H	4361	7230	ORPHA:145	Hereditary breast and ovarian cancer syndrome		532
HP:0008775	HP:0008775	Abnormal prostate morphology	0	MXI1 CL E G H	4601	7534	OMIM:176807	Prostate cancer		4
HP:0008775	HP:0008775	Abnormal prostate morphology	0	NAB2 CL E G H	4665	7627	ORPHA:2126	Solitary fibrous tumor/hemangiopericytoma	HP:0040284 - Very rare
HP:0008775	HP:0008775	Abnormal prostate morphology	0	NBN CL E G H	4683	7652	ORPHA:145	Hereditary breast and ovarian cancer syndrome		706
HP:0008775	HP:0008775	Abnormal prostate morphology	0	NTHL1 CL E G H	4913	8028	OMIM:616415	Familial adenomatous polyposis 3		2
HP:0008775	HP:0008775	Abnormal prostate morphology	0	PALB2 CL E G H	79728	26144	ORPHA:145	Hereditary breast and ovarian cancer syndrome		1349
HP:0008775	HP:0008775	Abnormal prostate morphology	0	PHF6 CL E G H	84295	18145	OMIM:301900	Borjeson-Forssman-Lehmann syndrome		29
HP:0008775	HP:0008775	Abnormal prostate morphology	0	PRTN3 CL E G H	5657	9495	ORPHA:900	Granulomatosis with polyangiitis
HP:0008775	HP:0008775	Abnormal prostate morphology	0	PTEN CL E G H	5728	9588	ORPHA:145	Hereditary breast and ovarian cancer syndrome		948
HP:0008775	HP:0008775	Abnormal prostate morphology	0	PTEN CL E G H	5728	9588	OMIM:176807	Prostate cancer		948
HP:0008775	HP:0008775	Abnormal prostate morphology	0	PTPN22 CL E G H	26191	9652	ORPHA:900	Granulomatosis with polyangiitis		3
HP:0008775	HP:0008775	Abnormal prostate morphology	0	RAD50 CL E G H	10111	9816	ORPHA:145	Hereditary breast and ovarian cancer syndrome		789
HP:0008775	HP:0008775	Abnormal prostate morphology	0	RAD51 CL E G H	5888	9817	ORPHA:145	Hereditary breast and ovarian cancer syndrome		9
HP:0008775	HP:0008775	Abnormal prostate morphology	0	RAD51C CL E G H	5889	9820	ORPHA:145	Hereditary breast and ovarian cancer syndrome		391
HP:0008775	HP:0008775	Abnormal prostate morphology	0	RAD51D CL E G H	5892	9823	ORPHA:145	Hereditary breast and ovarian cancer syndrome		345
HP:0008775	HP:0008775	Abnormal prostate morphology	0	RNASEL CL E G H	6041	10050	OMIM:601518	Prostate cancer, hereditary, 1		3
HP:0008775	HP:0008775	Abnormal prostate morphology	0	RNF43 CL E G H	54894	18505	ORPHA:157798	Serrated polyposis syndrome		5
HP:0008775	HP:0008775	Abnormal prostate morphology	0	STAT6 CL E G H	6778	11368	ORPHA:2126	Solitary fibrous tumor/hemangiopericytoma	HP:0040284 - Very rare	1
HP:0008775	HP:0008775	Abnormal prostate morphology	0	TP53 CL E G H	7157	11998	ORPHA:145	Hereditary breast and ovarian cancer syndrome		911
HP:0008775	HP:0008775	Abnormal prostate morphology	0	TP53 CL E G H	7157	11998	ORPHA:524	Li-Fraumeni syndrome		911
HP:0008775	HP:0008775	Abnormal prostate morphology	0	TP53 CL E G H	7157	11998	OMIM:151623	Li-Fraumeni syndrome		911
HP:0008775	HP:0008775	Abnormal prostate morphology	0	ZFHX3 CL E G H	463	777	OMIM:176807	Prostate cancer		6
HP:0008775	HP:0020126	Prostate mass	1	CL E G H
HP:0008775	HP:0008742	Prominent prostate median bar	1	CL E G H
HP:0008775	HP:0008711	Benign prostatic hyperplasia	1	CL E G H
HP:0008775	HP:0100787	Prostate neoplasm	1	AAGAB CL E G H	79719	25662	ORPHA:79501	Punctate palmoplantar keratoderma type 1		7
HP:0008775	HP:0100787	Prostate neoplasm	1	APC CL E G H	324	583	ORPHA:79665	Gardner syndrome		3179
HP:0008775	HP:0100787	Prostate neoplasm	1	AR CL E G H	367	644	OMIM:176807	Prostate cancer		125
HP:0008775	HP:0100787	Prostate neoplasm	1	BARD1 CL E G H	580	952	ORPHA:145	Hereditary breast and ovarian cancer syndrome		790
HP:0008775	HP:0100787	Prostate neoplasm	1	BMPR1A CL E G H	657	1076	ORPHA:157794	Hereditary mixed polyposis syndrome		385
HP:0008775	HP:0100787	Prostate neoplasm	1	BRCA1 CL E G H	672	1100	ORPHA:145	Hereditary breast and ovarian cancer syndrome		5769
HP:0008775	HP:0100787	Prostate neoplasm	1	BRCA2 CL E G H	675	1101	ORPHA:145	Hereditary breast and ovarian cancer syndrome		7642
HP:0008775	HP:0100787	Prostate neoplasm	1	BRCA2 CL E G H	675	1101	OMIM:176807	Prostate cancer		7642
HP:0008775	HP:0100787	Prostate neoplasm	1	BRIP1 CL E G H	83990	20473	ORPHA:145	Hereditary breast and ovarian cancer syndrome		1086
HP:0008775	HP:0000024	Prostatitis	1	BTK CL E G H	695	1133	OMIM:300755	Agammaglobulinemia, X-linked	.	109
HP:0008775	HP:0000024	Prostatitis	1	BTK CL E G H	695	1133	OMIM:307200	Isolated growth hormone deficiency, type III, with agammaglobulinemia	.	109
HP:0008775	HP:0100787	Prostate neoplasm	1	CDH1 CL E G H	999	1748	OMIM:176807	Prostate cancer		1003
HP:0008775	HP:0100787	Prostate neoplasm	1	CDKN2A CL E G H	1029	1787	ORPHA:524	Li-Fraumeni syndrome		289
HP:0008775	HP:0100787	Prostate neoplasm	1	CHEK2 CL E G H	11200	16627	ORPHA:145	Hereditary breast and ovarian cancer syndrome		833
HP:0008775	HP:0100787	Prostate neoplasm	1	CHEK2 CL E G H	11200	16627	ORPHA:524	Li-Fraumeni syndrome		833
HP:0008775	HP:0100787	Prostate neoplasm	1	CHEK2 CL E G H	11200	16627	OMIM:176807	Prostate cancer		833
HP:0008775	HP:0100787	Prostate neoplasm	1	COL14A1 CL E G H	7373	2191	ORPHA:79501	Punctate palmoplantar keratoderma type 1		2
HP:0008775	HP:0000024	Prostatitis	1	CTLA4 CL E G H	1493	2505	ORPHA:900	Granulomatosis with polyangiitis	HP:0040283 - Occasional	10
HP:0008775	HP:0100787	Prostate neoplasm	1	EPHB2 CL E G H	2048	3393	OMIM:603688	Prostate cancer/brain cancer susceptibility		7
HP:0008775	HP:0100787	Prostate neoplasm	1	FOXE1 CL E G H	2304	3806	OMIM:616534	Thyroid cancer, nonmedullary, 4		9
HP:0008775	HP:0100787	Prostate neoplasm	1	GREM1 CL E G H	26585	2001	ORPHA:157794	Hereditary mixed polyposis syndrome		9
HP:0008775	HP:0000024	Prostatitis	1	HGD CL E G H	3081	4892	ORPHA:56	Alkaptonuria	HP:0040282 - Frequent	77
HP:0008775	HP:0000024	Prostatitis	1	HLA-DPA1 CL E G H	3113	4938	ORPHA:900	Granulomatosis with polyangiitis	HP:0040283 - Occasional
HP:0008775	HP:0000024	Prostatitis	1	HLA-DPB1 CL E G H	3115	4940	ORPHA:900	Granulomatosis with polyangiitis	HP:0040283 - Occasional	1
HP:0008775	HP:0100787	Prostate neoplasm	1	KLF6 CL E G H	1316	2235	OMIM:176807	Prostate cancer		18
HP:0008775	HP:0100787	Prostate neoplasm	1	MAD1L1 CL E G H	8379	6762	OMIM:176807	Prostate cancer		5
HP:0008775	HP:0100787	Prostate neoplasm	1	MDM2 CL E G H	4193	6973	ORPHA:524	Li-Fraumeni syndrome		1
HP:0008775	HP:0100787	Prostate neoplasm	1	MRE11 CL E G H	4361	7230	ORPHA:145	Hereditary breast and ovarian cancer syndrome		532
HP:0008775	HP:0100787	Prostate neoplasm	1	MXI1 CL E G H	4601	7534	OMIM:176807	Prostate cancer		4
HP:0008775	HP:0100787	Prostate neoplasm	1	NAB2 CL E G H	4665	7627	ORPHA:2126	Solitary fibrous tumor/hemangiopericytoma
HP:0008775	HP:0100787	Prostate neoplasm	1	NBN CL E G H	4683	7652	ORPHA:145	Hereditary breast and ovarian cancer syndrome		706
HP:0008775	HP:0100787	Prostate neoplasm	1	NTHL1 CL E G H	4913	8028	OMIM:616415	Familial adenomatous polyposis 3		2
HP:0008775	HP:0100787	Prostate neoplasm	1	PALB2 CL E G H	79728	26144	ORPHA:145	Hereditary breast and ovarian cancer syndrome		1349
HP:0008775	HP:0008687	Hypoplasia of the prostate	1	PHF6 CL E G H	84295	18145	OMIM:301900	Borjeson-Forssman-Lehmann syndrome	.	29
HP:0008775	HP:0000024	Prostatitis	1	PRTN3 CL E G H	5657	9495	ORPHA:900	Granulomatosis with polyangiitis	HP:0040283 - Occasional
HP:0008775	HP:0100787	Prostate neoplasm	1	PTEN CL E G H	5728	9588	ORPHA:145	Hereditary breast and ovarian cancer syndrome		948
HP:0008775	HP:0100787	Prostate neoplasm	1	PTEN CL E G H	5728	9588	OMIM:176807	Prostate cancer		948
HP:0008775	HP:0000024	Prostatitis	1	PTPN22 CL E G H	26191	9652	ORPHA:900	Granulomatosis with polyangiitis	HP:0040283 - Occasional	3
HP:0008775	HP:0100787	Prostate neoplasm	1	RAD50 CL E G H	10111	9816	ORPHA:145	Hereditary breast and ovarian cancer syndrome		789
HP:0008775	HP:0100787	Prostate neoplasm	1	RAD51 CL E G H	5888	9817	ORPHA:145	Hereditary breast and ovarian cancer syndrome		9
HP:0008775	HP:0100787	Prostate neoplasm	1	RAD51C CL E G H	5889	9820	ORPHA:145	Hereditary breast and ovarian cancer syndrome		391
HP:0008775	HP:0100787	Prostate neoplasm	1	RAD51D CL E G H	5892	9823	ORPHA:145	Hereditary breast and ovarian cancer syndrome		345
HP:0008775	HP:0100787	Prostate neoplasm	1	RNASEL CL E G H	6041	10050	OMIM:601518	Prostate cancer, hereditary, 1		3
HP:0008775	HP:0100787	Prostate neoplasm	1	RNF43 CL E G H	54894	18505	ORPHA:157798	Serrated polyposis syndrome		5
HP:0008775	HP:0100787	Prostate neoplasm	1	STAT6 CL E G H	6778	11368	ORPHA:2126	Solitary fibrous tumor/hemangiopericytoma		1
HP:0008775	HP:0100787	Prostate neoplasm	1	TP53 CL E G H	7157	11998	ORPHA:145	Hereditary breast and ovarian cancer syndrome		911
HP:0008775	HP:0100787	Prostate neoplasm	1	TP53 CL E G H	7157	11998	OMIM:151623	Li-Fraumeni syndrome	.	911
HP:0008775	HP:0100787	Prostate neoplasm	1	TP53 CL E G H	7157	11998	ORPHA:524	Li-Fraumeni syndrome		911
HP:0008775	HP:0100787	Prostate neoplasm	1	ZFHX3 CL E G H	463	777	OMIM:176807	Prostate cancer		6
HP:0008775	HP:0012125	Prostate cancer	2	AAGAB CL E G H	79719	25662	ORPHA:79501	Punctate palmoplantar keratoderma type 1	HP:0040284 - Very rare	7
HP:0008775	HP:0012125	Prostate cancer	2	APC CL E G H	324	583	ORPHA:79665	Gardner syndrome	HP:0040284 - Very rare	3179
HP:0008775	HP:0012125	Prostate cancer	2	AR CL E G H	367	644	OMIM:176807	Prostate cancer	.	125
HP:0008775	HP:0012125	Prostate cancer	2	BARD1 CL E G H	580	952	ORPHA:145	Hereditary breast and ovarian cancer syndrome	HP:0040283 - Occasional	790
HP:0008775	HP:0012125	Prostate cancer	2	BMPR1A CL E G H	657	1076	ORPHA:157794	Hereditary mixed polyposis syndrome	HP:0040284 - Very rare	385
HP:0008775	HP:0012125	Prostate cancer	2	BRCA1 CL E G H	672	1100	ORPHA:145	Hereditary breast and ovarian cancer syndrome	HP:0040283 - Occasional	5769
HP:0008775	HP:0012125	Prostate cancer	2	BRCA2 CL E G H	675	1101	ORPHA:145	Hereditary breast and ovarian cancer syndrome	HP:0040283 - Occasional	7642
HP:0008775	HP:0012125	Prostate cancer	2	BRCA2 CL E G H	675	1101	OMIM:176807	Prostate cancer	.	7642
HP:0008775	HP:0012125	Prostate cancer	2	BRIP1 CL E G H	83990	20473	ORPHA:145	Hereditary breast and ovarian cancer syndrome	HP:0040283 - Occasional	1086
HP:0008775	HP:0012125	Prostate cancer	2	CDH1 CL E G H	999	1748	OMIM:176807	Prostate cancer	.	1003
HP:0008775	HP:0012125	Prostate cancer	2	CDKN2A CL E G H	1029	1787	ORPHA:524	Li-Fraumeni syndrome	HP:0040284 - Very rare	289
HP:0008775	HP:0012125	Prostate cancer	2	CHEK2 CL E G H	11200	16627	ORPHA:145	Hereditary breast and ovarian cancer syndrome	HP:0040283 - Occasional	833
HP:0008775	HP:0012125	Prostate cancer	2	CHEK2 CL E G H	11200	16627	ORPHA:524	Li-Fraumeni syndrome	HP:0040284 - Very rare	833
HP:0008775	HP:0012125	Prostate cancer	2	CHEK2 CL E G H	11200	16627	OMIM:176807	Prostate cancer	.	833
HP:0008775	HP:0012125	Prostate cancer	2	COL14A1 CL E G H	7373	2191	ORPHA:79501	Punctate palmoplantar keratoderma type 1	HP:0040284 - Very rare	2
HP:0008775	HP:0012125	Prostate cancer	2	EPHB2 CL E G H	2048	3393	OMIM:603688	Prostate cancer/brain cancer susceptibility	.	7
HP:0008775	HP:0012125	Prostate cancer	2	FOXE1 CL E G H	2304	3806	OMIM:616534	Thyroid cancer, nonmedullary, 4		9
HP:0008775	HP:0012125	Prostate cancer	2	GREM1 CL E G H	26585	2001	ORPHA:157794	Hereditary mixed polyposis syndrome	HP:0040284 - Very rare	9
HP:0008775	HP:0012125	Prostate cancer	2	KLF6 CL E G H	1316	2235	OMIM:176807	Prostate cancer	.	18
HP:0008775	HP:0012125	Prostate cancer	2	MAD1L1 CL E G H	8379	6762	OMIM:176807	Prostate cancer	.	5
HP:0008775	HP:0012125	Prostate cancer	2	MDM2 CL E G H	4193	6973	ORPHA:524	Li-Fraumeni syndrome	HP:0040284 - Very rare	1
HP:0008775	HP:0012125	Prostate cancer	2	MRE11 CL E G H	4361	7230	ORPHA:145	Hereditary breast and ovarian cancer syndrome	HP:0040283 - Occasional	532
HP:0008775	HP:0012125	Prostate cancer	2	MXI1 CL E G H	4601	7534	OMIM:176807	Prostate cancer	.	4
HP:0008775	HP:0012125	Prostate cancer	2	NAB2 CL E G H	4665	7627	ORPHA:2126	Solitary fibrous tumor/hemangiopericytoma	HP:0040284 - Very rare
HP:0008775	HP:0012125	Prostate cancer	2	NBN CL E G H	4683	7652	ORPHA:145	Hereditary breast and ovarian cancer syndrome	HP:0040283 - Occasional	706
HP:0008775	HP:0012125	Prostate cancer	2	NTHL1 CL E G H	4913	8028	OMIM:616415	Familial adenomatous polyposis 3		2
HP:0008775	HP:0012125	Prostate cancer	2	PALB2 CL E G H	79728	26144	ORPHA:145	Hereditary breast and ovarian cancer syndrome	HP:0040283 - Occasional	1349
HP:0008775	HP:0012125	Prostate cancer	2	PTEN CL E G H	5728	9588	ORPHA:145	Hereditary breast and ovarian cancer syndrome	HP:0040283 - Occasional	948
HP:0008775	HP:0012125	Prostate cancer	2	PTEN CL E G H	5728	9588	OMIM:176807	Prostate cancer	.	948
HP:0008775	HP:0012125	Prostate cancer	2	RAD50 CL E G H	10111	9816	ORPHA:145	Hereditary breast and ovarian cancer syndrome	HP:0040283 - Occasional	789
HP:0008775	HP:0012125	Prostate cancer	2	RAD51 CL E G H	5888	9817	ORPHA:145	Hereditary breast and ovarian cancer syndrome	HP:0040283 - Occasional	9
HP:0008775	HP:0012125	Prostate cancer	2	RAD51C CL E G H	5889	9820	ORPHA:145	Hereditary breast and ovarian cancer syndrome	HP:0040283 - Occasional	391
HP:0008775	HP:0012125	Prostate cancer	2	RAD51D CL E G H	5892	9823	ORPHA:145	Hereditary breast and ovarian cancer syndrome	HP:0040283 - Occasional	345
HP:0008775	HP:0012125	Prostate cancer	2	RNASEL CL E G H	6041	10050	OMIM:601518	Prostate cancer, hereditary, 1	.	3
HP:0008775	HP:0012125	Prostate cancer	2	RNF43 CL E G H	54894	18505	ORPHA:157798	Serrated polyposis syndrome	HP:0040284 - Very rare	5
HP:0008775	HP:0012125	Prostate cancer	2	STAT6 CL E G H	6778	11368	ORPHA:2126	Solitary fibrous tumor/hemangiopericytoma	HP:0040284 - Very rare	1
HP:0008775	HP:0012125	Prostate cancer	2	TP53 CL E G H	7157	11998	ORPHA:145	Hereditary breast and ovarian cancer syndrome	HP:0040283 - Occasional	911
HP:0008775	HP:0012125	Prostate cancer	2	TP53 CL E G H	7157	11998	OMIM:151623	Li-Fraumeni syndrome	.	911
HP:0008775	HP:0012125	Prostate cancer	2	TP53 CL E G H	7157	11998	ORPHA:524	Li-Fraumeni syndrome	HP:0040284 - Very rare	911
HP:0008775	HP:0012125	Prostate cancer	2	ZFHX3 CL E G H	463	777	OMIM:176807	Prostate cancer	.	6

Genes (42) :AAGAB APC AR BARD1 BMPR1A BRCA1 BRCA2 BRIP1 BTK CDH1 CDKN2A CHEK2 COL14A1 CTLA4 EPHB2 FOXE1 GREM1 HGD HLA-DPA1 HLA-DPB1 KLF6 MAD1L1 MDM2 MRE11 MXI1 NAB2 NBN NTHL1 PALB2 PHF6 PRTN3 PTEN PTPN22 RAD50 RAD51 RAD51C RAD51D RNASEL RNF43 STAT6 TP53 ZFHX3

Diseases (18) :ORPHA:79501 ORPHA:79665 OMIM:176807 ORPHA:145 ORPHA:157794 OMIM:300755 OMIM:307200 ORPHA:524 ORPHA:900 OMIM:603688 OMIM:616534 ORPHA:56 ORPHA:2126 OMIM:616415 OMIM:301900 OMIM:601518 ORPHA:157798 OMIM:151623

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.

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