Human Phenotype Ontology 
Grandparent Node:
expandAbnormal foot morphology (HP:0001760)help
Grandparent Node:
expandAbnormal lower limb bone morphology (HP:0040069)help
Parent Node:
expandAbnormal foot bone ossification (HP:0010675)help
Parent Node:
expandAbnormal metatarsal morphology (HP:0001832)help
..Starting node
..expandAbnormal metatarsal ossification (HP:0008371)help
Term ID: 8371
Name: Abnormal metatarsal ossification
Synonym: Abnormal maturation of long bone of foot; Abnormal ossification involving metatarsal bones
Definition: Any abnormal process of ossification of the metatarsal bones, which normally are each ossified from two centers: one for the body, and one for the head (metatarsal II,III,IV, and V) and one for the body and one for the base (metatarsal I). The ossification process begins in the center of the body about the ninth week, and extends toward either extremity. The center for the base of the first metatarsal appears about the third year, and the centers for the heads of the other bones between the fifth and eighth years. They join the bodies between the eighteenth and twentieth years.
Comments:
Reference: HP:0008371
Genes and Diseases:
 
       Child Nodes:
........expandNonossified fifth metatarsal (HP:0008087) help

 Sister Nodes: 
..expandAbnormality of metatarsal epiphysis (HP:0010630) help
..expandAbnormality of the fifth metatarsal bone (HP:0008089) help
..expandAbnormality of the first metatarsal bone (HP:0010054) help
..expandAbnormality of the fourth metatarsal bone (HP:0040035) help
..expandAbnormality of the second metatarsal bone (HP:0040034) help
..expandAbnormality of the third metatarsal bone (HP:0010672) help
..expandAplasia/Hypoplasia of metatarsal bones (HP:0001964) help
..expandBroad metatarsal (HP:0001783) help
..expandDistal tapering of metatarsals (HP:0008133) help
..expandDuplication of metatarsal bones (HP:0001449) help
..expandExpanded metatarsals with widened medullary cavities (HP:0008102) help
..expandFlattened metatarsal heads (HP:0005194) help
..expandMetatarsal diaphyseal endosteal sclerosis (HP:0008114) help
..expandMetatarsal osteolysis (HP:0001473) help
..expandMetatarsal periosteal thickening (HP:0008074) help
..expandMetatarsal synostosis (HP:0001440) help
..expandMetatarsus adductus (HP:0001840) help
..expandMetatarsus valgus (HP:0010508) help
..expandOsteoporotic metatarsal (HP:0004699) help
..expandSecond metatarsal posteriorly placed (HP:0008125) help
..expandThin metatarsal cortices (HP:0008078) help
..expandY-shaped metatarsals (HP:0010567) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0008371HP:0008371Abnormal metatarsal ossification0FLNA CL E G H23163754OMIM:304120Otopalatodigital syndrome, type II493
HP:0008371HP:0008087Nonossified fifth metatarsal1FLNA CL E G H23163754OMIM:304120Otopalatodigital syndrome, type II.493


Genes (1) :FLNA

Diseases (1) :OMIM:304120
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.