Human Phenotype Ontology 
Grandparent Node:
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Abnormality of skin morphology (HP:0011121)help
Parent Node:
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Ectopic calcification (HP:0010766)help
Parent Node:
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Generalized abnormality of skin (HP:0011354)help
..Starting node
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Subcutaneous calcification (HP:0007618)help
Term ID: 7618
Name: Subcutaneous calcification
Synonym: Skin calcification
Definition: Deposition of calcium salts in subcutaneous tissue (i.e., the the lowermost layer of the integument).
Comments:
Reference: HP:0007618
Genes and Diseases:
 
       Child Nodes:

 Sister Nodes: 
..expandAbnormality of subcutaneous fat tissue (HP:0001001) help
..expandCutaneous photosensitivity (HP:0000992) help
..expandDermatological manifestations of systemic disorders (HP:0001005) help
..expandDesquamation of skin soon after birth (HP:0007549) help
..expandEctodermal dysplasia (HP:0000968) help
..expandFlushing (HP:0031284) help
..expandFragile skin (HP:0001030) help
..expandGeneralized papillary lesions (HP:0007482) help
..expandPoor wound healing (HP:0001058) help
..expandPrematurely aged appearance (HP:0007495) help
..expandVascular skin abnormality (HP:0011276) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0007618HP:0007618Subcutaneous calcification0FGF23 CL E G H80743680OMIM:617993TUMORAL CALCINOSIS, HYPERPHOSPHATEMIC, FAMILIAL, 2; HFTC251
HP:0007618HP:0007618Subcutaneous calcification0LMNA CL E G H40006636ORPHA:79474Atypical Werner syndromeHP:0040281 - Very frequent645
HP:0007618HP:0007618Subcutaneous calcification0PSMC3 CL E G H57029549OMIM:619354DEAFNESS, CATARACT, IMPAIRED INTELLECTUAL DEVELOPMENT, AND POLYNEUROPATHY; DCIDP
HP:0007618HP:0007618Subcutaneous calcification0WRN CL E G H748612791OMIM:277700Werner syndrome.310
HP:0007618HP:0007618Subcutaneous calcification0WRN CL E G H748612791ORPHA:902Werner syndromeHP:0040282 - Frequent310


Genes (4) :FGF23 LMNA PSMC3 WRN

Diseases (5) :OMIM:617993 ORPHA:79474 OMIM:619354 OMIM:277700 ORPHA:902
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.