Human Phenotype Ontology 
Grandparent Node:
Hyperpigmentation of the skin (HP:0000953)help
Grandparent Node:
Hypopigmentation of the skin (HP:0001010)help
Parent Node:
Mixed hypo- and hyperpigmentation of the skin (HP:0009123)help
..Starting node
Patchy hypo- and hyperpigmentation (HP:0007509)help
Term ID: 7509
Name: Patchy hypo- and hyperpigmentation
Synonym: Patchy hypo- and hyper-pigmentation
Reference: HP:0007509
Genes and Diseases:
       Child Nodes:

 Sister Nodes: 
..expandAreas of hypopigmentation and hyperpigmentation that do not follow Blaschko lines (HP:0007402) help
..expandAxillary and groin hyperpigmentation and hypopigmentation (HP:0007471) help
..expandHyperpigmented/hypopigmented macules (HP:0007441) help
..expandIncreased groin pigmentation with raindrop depigmentation (HP:0007450) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
HPO disease - gene - phenotype typical associations:
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0007509HP:0007509Patchy hypo- and hyperpigmentation0LMNA CL E G H40006636ORPHA:79474Atypical Werner syndromeHP:0040281 - Very frequent645
HP:0007509HP:0007509Patchy hypo- and hyperpigmentation0SMS CL E G H661111123ORPHA:3063X-linked intellectual disability, Snyder typeHP:0040283 - Occasional19
HP:0007509HP:0007509Patchy hypo- and hyperpigmentation0UBE2A CL E G H731912472ORPHA:163956X-linked intellectual disability, Nascimento typeHP:0040283 - Occasional7

Genes (3) :LMNA SMS UBE2A

Diseases (3) :ORPHA:79474 ORPHA:3063 ORPHA:163956

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.