Human Phenotype Ontology

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Hello! Guest! Please Login or Register! Clinician Mode

Examples Gene: MT-ND1, POLG, Region: M:1-1000 Variant: m.8993T>G, 1:g.10042757T>C rs3888511 MSCV_0000006, ClinVar: RCV000000015, Disease: Leigh syndrome, Phenotype: Retinopathy

Grandparent Node:
Abnormal bleeding (HP:0001892)

Parent Node:
Prolonged bleeding following procedure (HP:0011890)

..Starting node
..Prolonged bleeding after surgery (HP:0004846)

Term ID:

4846

Name:

Prolonged bleeding after surgery

Synonym:

Excessive bleeding during surgery; Prolonged bleeding after surgery; Protracted bleeding after surgery

Definition:

Bleeding that persists longer than the normal time following a surgical procedure.

Comments:

Reference:

HP:0004846

Genes and Diseases:

Child Nodes:

Sister Nodes:

Post-partum hemorrhage (HP:0011891)

Prolonged bleeding after dental extraction (HP:0006298)

Prolonged bleeding following circumcision (HP:0030137)

Input	HPO ID	HPO term	Distance	Gene	Gene id entrez	HGNC ID	DiseaseId	DiseaseName	Frequency	ClinVar variants
HPO disease - gene - phenotype typical associations:
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0004846	HP:0004846	Prolonged bleeding after surgery	0	F10 CL E G H	2159	3528	ORPHA:328	Congenital factor X deficiency	HP:0040281 - Very frequent	33
HP:0004846	HP:0004846	Prolonged bleeding after surgery	0	F13A1 CL E G H	2162	3531	ORPHA:331	Congenital factor XIII deficiency	HP:0040283 - Occasional	60
HP:0004846	HP:0004846	Prolonged bleeding after surgery	0	F13B CL E G H	2165	3534	ORPHA:331	Congenital factor XIII deficiency	HP:0040283 - Occasional	32
HP:0004846	HP:0004846	Prolonged bleeding after surgery	0	F13B CL E G H	2165	3534	OMIM:613235	Factor XIIIB deficiency	.	32
HP:0004846	HP:0004846	Prolonged bleeding after surgery	0	F5 CL E G H	2153	3542	ORPHA:326	Congenital factor V deficiency	HP:0040283 - Occasional	159
HP:0004846	HP:0004846	Prolonged bleeding after surgery	0	F7 CL E G H	2155	3544	ORPHA:327	Congenital factor VII deficiency	HP:0040282 - Frequent	70
HP:0004846	HP:0004846	Prolonged bleeding after surgery	0	F8 CL E G H	2157	3546	ORPHA:177926	Bleeding disorder in hemophilia A carriers without FVIII deficiency	HP:0040282 - Frequent	303
HP:0004846	HP:0004846	Prolonged bleeding after surgery	0	F8 CL E G H	2157	3546	ORPHA:169805	Moderate hemophilia A	HP:0040283 - Occasional	303
HP:0004846	HP:0004846	Prolonged bleeding after surgery	0	F8 CL E G H	2157	3546	ORPHA:169802	Severe hemophilia A	HP:0040282 - Frequent	303
HP:0004846	HP:0004846	Prolonged bleeding after surgery	0	GP1BA CL E G H	2811	4439	ORPHA:274	Bernard-Soulier syndrome	HP:0040283 - Occasional	23
HP:0004846	HP:0004846	Prolonged bleeding after surgery	0	GP1BA CL E G H	2811	4439	OMIM:231200	BERNARD-SOULIER SYNDROME; BSS		23
HP:0004846	HP:0004846	Prolonged bleeding after surgery	0	GP1BB CL E G H	2812	4440	ORPHA:274	Bernard-Soulier syndrome	HP:0040283 - Occasional	8
HP:0004846	HP:0004846	Prolonged bleeding after surgery	0	GP1BB CL E G H	2812	4440	OMIM:231200	BERNARD-SOULIER SYNDROME; BSS		8
HP:0004846	HP:0004846	Prolonged bleeding after surgery	0	GP9 CL E G H	2815	4444	ORPHA:274	Bernard-Soulier syndrome	HP:0040283 - Occasional	21
HP:0004846	HP:0004846	Prolonged bleeding after surgery	0	GP9 CL E G H	2815	4444	OMIM:231200	BERNARD-SOULIER SYNDROME; BSS		21
HP:0004846	HP:0004846	Prolonged bleeding after surgery	0	ITGA2B CL E G H	3674	6138	ORPHA:849	Glanzmann thrombasthenia	HP:0040282 - Frequent	69
HP:0004846	HP:0004846	Prolonged bleeding after surgery	0	ITGB3 CL E G H	3690	6156	ORPHA:849	Glanzmann thrombasthenia	HP:0040282 - Frequent	80
HP:0004846	HP:0004846	Prolonged bleeding after surgery	0	ITGB3 CL E G H	3690	6156	OMIM:619267	GLANZMANN THROMBASTHENIA 2; GT2		80
HP:0004846	HP:0004846	Prolonged bleeding after surgery	0	LMAN1 CL E G H	3998	6631	ORPHA:35909	Combined deficiency of factor V and factor VIII	HP:0040283 - Occasional	56
HP:0004846	HP:0004846	Prolonged bleeding after surgery	0	MCFD2 CL E G H	90411	18451	ORPHA:35909	Combined deficiency of factor V and factor VIII	HP:0040283 - Occasional	77
HP:0004846	HP:0004846	Prolonged bleeding after surgery	0	P2RY12 CL E G H	64805	18124	OMIM:609821	Bleeding disorder, platelet-type, 8		5
HP:0004846	HP:0004846	Prolonged bleeding after surgery	0	SERPINE1 CL E G H	5054	8583	ORPHA:465	Congenital plasminogen activator inhibitor type 1 deficiency	HP:0040281 - Very frequent	39
HP:0004846	HP:0004846	Prolonged bleeding after surgery	0	VWF CL E G H	7450	12726	OMIM:193400	Von willebrand disease, type 1		533
HP:0004846	HP:0004846	Prolonged bleeding after surgery	0	VWF CL E G H	7450	12726	OMIM:277480	Von willebrand disease, type 3	.	533

Genes (16) :F10 F13A1 F13B F5 F7 F8 GP1BA GP1BB GP9 ITGA2B ITGB3 LMAN1 MCFD2 P2RY12 SERPINE1 VWF

Diseases (17) :ORPHA:328 ORPHA:331 OMIM:613235 ORPHA:326 ORPHA:327 ORPHA:177926 ORPHA:169805 ORPHA:169802 ORPHA:274 OMIM:231200 ORPHA:849 OMIM:619267 ORPHA:35909 OMIM:609821 ORPHA:465 OMIM:193400 OMIM:277480

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.

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