Human Phenotype Ontology 
Grandparent Node:
expandAbnormal vertebral morphology (HP:0003468)help
Parent Node:
expandAbnormal form of the vertebral bodies (HP:0003312)help
..Starting node
..expandIncreased vertebral height (HP:0004570)help
Term ID: 4570
Name: Increased vertebral height
Synonym: Tall vertebral bodies
Definition: Increased top to bottom height of vertebral bodies.
Comments:
Reference: HP:0004570
Genes and Diseases:
 
       Child Nodes:
........expandIncreased anterior vertebral height (HP:0004581) help
........expandTall lumbar vertebral bodies (HP:0008421) help

 Sister Nodes: 
..expandAbnormality of spinal facet joint (HP:0030870) help
..expandAbnormality of the vertebral endplates (HP:0005106) help
..expandAbnormality of the vertebral spinous processes (HP:0008516) help
..expandAnisospondyly (HP:0002879) help
..expandAnterior concavity of thoracic vertebrae (HP:0004611) help
..expandBeaking of vertebral bodies (HP:0004568) help
..expandBiconcave vertebral bodies (HP:0004586) help
..expandBiconvex vertebral bodies (HP:0004625) help
..expandBifid thoracic vertebrae (HP:0008437) help
..expandCuboid-shaped vertebral bodies (HP:0004634) help
..expandDisc-like vertebral bodies (HP:0004591) help
..expandHemivertebrae (HP:0002937) help
..expandHypoplastic vertebral bodies (HP:0008479) help
..expandIrregularity of vertebral bodies (HP:0004582) help
..expandOvoid vertebral bodies (HP:0003300) help
..expandPatchy distortion of vertebrae (HP:0004609) help
..expandPear-shaped vertebrae (HP:0004566) help
..expandPlatyspondyly (HP:0000926) help
..expandSandwich appearance of vertebral bodies (HP:0004618) help
..expandTrapezoidal vertebral body (HP:0005621) help
..expandVertebral arch anomaly (HP:0008438) help
..expandVertebral clefting (HP:0008428) help
..expandVertebral wedging (HP:0008422) help
InputHPO IDHPO termDistanceGeneGene id entrezHGNC IDDiseaseIdDiseaseNameFrequencyOnsetHGMD variantsClinVar variants
 
HPO disease - gene - phenotype typical associations:
 
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0004570HP:0004570Increased vertebral height0CCDC8 CL E G H8398725367ORPHA:26163M syndromeHP:0040281 - Very frequent5
HP:0004570HP:0004570Increased vertebral height0CCDC8 CL E G H8398725367OMIM:614205THREE M SYNDROME 3; 3M35
HP:0004570HP:0004570Increased vertebral height0CUL7 CL E G H982021024OMIM:2737503-M syndrome 1.127
HP:0004570HP:0004570Increased vertebral height0CUL7 CL E G H982021024ORPHA:26163M syndromeHP:0040281 - Very frequent127
HP:0004570HP:0004570Increased vertebral height0FGFR3 CL E G H22613690OMIM:610474Camptodactyly, tall stature, and hearing loss syndrome.145
HP:0004570HP:0004570Increased vertebral height0ITCH CL E G H8373713890OMIM:613385AUTOIMMUNE DISEASE, MULTISYSTEM, WITH FACIAL DYSMORPHISM; ADMFD3
HP:0004570HP:0004570Increased vertebral height0MAN2B1 CL E G H41256826OMIM:248500Alpha-mannosidosis.136
HP:0004570HP:0004570Increased vertebral height0NOTCH2 CL E G H48537882OMIM:102500Hajdu-Cheney syndrome138
HP:0004570HP:0004570Increased vertebral height0OBSL1 CL E G H2336329092ORPHA:26163M syndromeHP:0040281 - Very frequent143
HP:0004570HP:0004570Increased vertebral height0PPP1R15B CL E G H8491914951OMIM:616817Microcephaly, short stature, and impaired glucose metabolism 2HP:0040283 - Occasional2
HP:0004570HP:0004570Increased vertebral height0TRPV4 CL E G H5934118083ORPHA:93304Autosomal dominant brachyolmiaHP:0040281 - Very frequent214
HP:0004570HP:0004581Increased anterior vertebral height1 CL E G H
HP:0004570HP:0008421Tall lumbar vertebral bodies1NOTCH2 CL E G H48537882OMIM:102500Hajdu-Cheney syndrome.138


Genes (9) :CCDC8 CUL7 FGFR3 ITCH MAN2B1 NOTCH2 OBSL1 PPP1R15B TRPV4

Diseases (9) :ORPHA:2616 OMIM:614205 OMIM:273750 OMIM:610474 OMIM:613385 OMIM:248500 OMIM:102500 OMIM:616817 ORPHA:93304
 

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.