Human Phenotype Ontology

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Hello! Guest! Please Login or Register! Clinician Mode

Examples Gene: MT-ND1, POLG, Region: M:1-1000 Variant: m.8993T>G, 1:g.10042757T>C rs3888511 MSCV_0000006, ClinVar: RCV000000015, Disease: Leigh syndrome, Phenotype: Retinopathy

Grandparent Node:
Abnormal long bone morphology (HP:0011314)

Grandparent Node:
Abnormality of limb bone morphology (HP:0002813)

Parent Node:
Abnormal metaphysis morphology (HP:0000944)

..Starting node
..Corner fracture of metaphysis (HP:0003908)

Term ID:

3908

Name:

Corner fracture of metaphysis

Synonym:

Bucket handle fracture; Metaphyseal corner fracture

Definition:

Fracture or fragmentation at the lateral portion of the metaphysis of a long bone. The radiographic appearance is that of a small corner of metaphysis separated from the metaphyseal edge by thin linear radiolucency. This feature can be observed in child abuse but fragmented appearance of the metaphysis or facture-like lesions can also be detected in the setting of certain skeletal dysplasias.

Comments:

Reference:

HP:0003908

Genes and Diseases:

Child Nodes:

Sister Nodes:

Abnormal lower-limb metaphysis morphology (HP:0006490)

Abnormal metaphyseal trabeculation (HP:0005089)

Abnormal metaphyseal vascular invasion (HP:0003562)

Abnormal upper limb metaphysis morphology (HP:0009809)

Alternating radiolucent and radiodense metaphyseal lines (HP:0031016)

Dense metaphyseal bands (HP:0100959)

Dumbbell-shaped metaphyses (HP:0002810)

Enlarged metaphyses (HP:0003051)

Metaphyseal cupping (HP:0003021)

Metaphyseal dysplasia (HP:0100255)

Metaphyseal enchondromatosis (HP:0005868)

Metaphyseal irregularity (HP:0003025)

Metaphyseal rarefaction (HP:0004980)

Metaphyseal sclerosis (HP:0004979)

Metaphyseal spurs (HP:0005054)

Metaphyseal striations (HP:0031367)

Metaphyseal widening (HP:0003016)

obsolete Metaphyseal dysostosis (HP:0005899)

Input	HPO ID	HPO term	Distance	Gene	Gene id entrez	HGNC ID	DiseaseId	DiseaseName	Frequency	ClinVar variants
HPO disease - gene - phenotype typical associations:
HPO disease - gene - phenotype less frequent non-typical associations:
HP:0003908	HP:0003908	Corner fracture of metaphysis	0	COL2A1 CL E G H	1280	2200	ORPHA:93315	Spondylometaphyseal dysplasia, 'corner fracture' type	HP:0040281 - Very frequent	284
HP:0003908	HP:0003908	Corner fracture of metaphysis	0	FN1 CL E G H	2335	3778	ORPHA:93315	Spondylometaphyseal dysplasia, 'corner fracture' type	HP:0040281 - Very frequent	9

Genes (2) :COL2A1 FN1

Diseases (1) :ORPHA:93315

Human Phenotype Ontology(HPO) is developed by the Human Phenotype Ontology Consortium. The version used here is December 15 2022 release.

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